for 6RANTSNIH GUIDE US. DEPARTMENT O f HEALTH. EDUCATION, AND YVELFARE

Vol. 6 , No. 10, May 18, 1977

IN T H I S ISSUE:

SENIOR INTERNATIONAL FELLOWSHIPS FOGARTY INTERNATIONAL CENTER

Announcement of fellowships offered by Fogarty International Center. Receipt date for applications: December 1.

PERSONNEL VACANCY

Nominations and applications invited for position of Associate Direc,tor for Extramural Research and Training, NIH.

CORRECTION - N C I CONSTRUCTION PROGRAM

No more than 50% Federal financial participation effective for applications submitted f o r February 1, 1978, receipt date rather than October 1, 1977.

COMPENSATION OF INJURED RESEARCH SUBJECTS

Copies of publication available. c

I HAW YOU WVED?

I f your present address d i f f e r s from that shown on the address label , please send your new &ss to: Gnmts and Contract Guide Distr ibut ion Center, Division of Research Grants. NIH, Room 219, Westwood Building, Bethsda , Umjtand 20014. and attach your adohas Lcbel to your l e t t e r . h m p t notice of yourchange of address w i l l prevent your n h e from beingremoved from our mailing l i s t .

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The GUIDE is published a t irreguzar intervals to provide policy and adrtinistrative information to indiv iduab and ozyanizations who need t o be kept informed of requiremenb and changes i n grants and contracts a c t i v i t i e s ah in i s t e red by the National Ins t i tu tes of HeaZth.

Supplements, printed on y e 2 l m paper, C L T ~ pubtished by the respective awarding m i t s concerning new projects , so l ic i ta t ions of sources, and llequest s for proposa ls.

NATIONAL HEART, LUNG, AND BLOOD I N S T I T U T E

MEDICAL SCHOOL PULMONARY FACULTY TRAINING AWARD

Announcement of new competition for these awards. Letter of intent due June 15. 1977.

PULMONARY ACADEMIC AWARD

Announcement of national competition. Letter of intent due June 15, 1977.

SPECIAL DENTAL RESEARCH AWARD

Revision of announcement contained on page 15, Vol. 5, No. 20, of the NIH Guide f o r Grants and Contracts.

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N I H G u i d e f o r G r a n t s a n d C o n t r a c t s V o l . 6 , N o . 10, May 18, 1977

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P a g e One

SENIOR INTERNATIONAL FELLOWSHIPS

FOGARTY INTERNATIONAL CENTER A N N O U N C E M E N T

The Senior International Fellowship Program provides opportunities to U.S. schools of medicine, osteopathy, dentistry, and public health to nominate outstanding faculty members at mid-career, who have demonstrated productive scholarship and recognized stature in their profession, to go abroad to study and share their expertise [PHS Act, Section 307(b)(2)1. It is intended that this award be a career-enhancing educational experience with mutual benefits to all involved. It is the aim of these fellowships to:

1. increase the interchange of ideas of mutual interest between U . S . scholars in academic medicine and those of other nations of the world;

2. permit the exchange of the latest advances in a particular area of medicine, both basic and clinical;

3 . permit participation abroad in on-going research in the medical sciences or in science areas related to medicine; and

4 . improve the academic, research and/or clinical biomedical potential of the U.S. medical institution.

E l i g i b i l i t y Requirements To be eligible for a Senior International Fellow-ship, the nominee must :

1. be a U.S. citizen, or have permanent resident status;

2. hold a full-time appointment on the staff of the nominating institution;

3 . have at least five years' experience beyond the doctorate or have professional medical degree in research, teaching, or other relevant professional work;

4 . possess the linguistic abilities necessary for learning and for profitable discussion with colleagues in the country proposed for the fellowship.

Program Requirements The applicant is expected to pursue during the fellowship period at the host institution a specific, well-designed project of mutual interest related to his or her on-going work as well as to that which will be continued upon return. The type of project would be depend­ent upon the professional discipline of the applicant, such as, basic laboratory o r clinical research, data collection and analysis, or operational research.

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The intrinsic technical merit of the project is one of several important factors to be considered in evaluating the totality of the application as to its fulfillment of the basic purpose of the program. The following factors will be given weight in review of the application:

e qualifications of the applicant e potentiality for career enhancement e opportunity for close, interpersonal technical interchange 0 benefit to the U.S. nominating institution 0 benefit to the foreign host institution e technical merit and significance of the project.

Applications cannot be considered as fulfilling the purpose of the program where there is not a sufficient period of time for in-depth interaction by the applicant with the host institution or where the benefit is primarily for oily one of the parties. Thus applications having any of the 'following as the major feature cannot be accepted:

visits to multiple institutions and/or for brief periods attendance at conferences attendance in formal training courses full-time clinical, technical, o r teaching service completely independent study.

Nominations The nomination of an individual for this fellowship will be made by the sponsoring U.S. institution. The letter of nomination must be from the President, Dean, or other appropriate official of the nominating institution, and shall specify the expected benefits to the institution of the applicant's proposed program. Additional information as considered pertinent may be submitted by the institution in support of the nomination. A letter of invitation from an appropriate individual at the host institution abroad attesting to the willingness of the institution to sponsor the appli­cant and outlining any benefits which may accrue will be a necessary part of the application. In addition, letters of recommendation from colleagues or others who are acquainted with the individual's scientific competence will be solicited by the applicant. The nominee will be judged on these evidences of academic competence and on ability to pursue the proposed program.

Documents t o be submitted The applicant must submit a research fellowship application and a signed HEW-596 form (Protection of Human Subjects Certi­_ _ ­fication). In addition, the applicant must arrange for the submission of supporting documents on his or her behalf (reference reports, letter of invitation from host institution, etc.).

Application Materia2 Individuals are encouraged to review the eligibility criteria before requesting application kits from their Dean's office. Application kits will be sent to the office of Deans of schools of medicine, osteopathy, dentistry, and public health upon request. Application kits will not be sent by NIH directly to applicants. Deans' offices should request application materials from the Scholars and Fellowships Program Branch, Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20014.

NIH Guide f o r Grants and Contracts Vol . 6 , No, 10, May 18, 1977 Page Three

t4 Receipt Date f o r AppZications Completed applications must be mailed to the Division of Research Grants, National Institutes of Health, Bethesda, Maryland 20014, by December 1 of each year. Applications received after that date will be returned to the applicant unless it is specifically requested by the applicant to be held for the next year's review.

Selection of Awardee8 Nominations will be reviewed for scientific merit by an NIH review committee. Individuals selected will represent a broad spectrum of interests but will be representative of current needs and concerns. An applicant will be notified by the Fogarty International Center of the final action on his application by an award notice or by a letter. Results will be announced in May.

Stipends will be determined at the rate of $18,000 for a 12-month period, prorated for shorter periods.

AZZowances Fellows will be reimbursed for the cost of round-trip economy travel fare from the nominating institution to the foreign host institution when U.S. flag carriers are used for (1) departure from or entry into the United States and (2) any other portion of the trip where U.S. carriers are available. When U.S. carriers are unavailable for any portion of the trip,the NIH awarding unit should be notified. No allowance will be provided for dependents, unrelated travel, or shipment of household effects.

An unaccompanied baggage allowance for personal effects, not to exceed 100 pounds, to be shipped air freight may be authorized.

W Upon justified request from the nominating institution, the Fogarty Inter-national Center will provide funds not to exceed $2,000 per 12-month period to help defray such expenses as fees, research supplies, and equipment to the foreign host institution.

SuppZementation Supplementation is the provision of funds to a fellow in addition to the stipend amount provided by the NIH award. Institutions are expected to follow their normal policies and guidelines governing supplementa­tion. No supplementation may be provided from Federal funds.

The conditions for receiving the additional stipend amount must be designed to avoid imposition of service or teaching requirements which would detract from or prolong the fellowship.

Concurrent Benefits Stipends under the Senior International Fellowship Program may not be received concurrently with any other Federal educational award (fellowship, traineeship, etc.), except that fellows may accept concurrent educational remuneration from the Veterans Administration (e.g. G . I . Bill) and loans from Federal funds.

Tenure Applicants may request support for a period three to twelve months in length.

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Activation Date An awardee may a c t i v a t e h i s o r h e r f e l l o w s h i p a t any t i m e du r ing t h e 12-month p e r i o d fo l lowing t h e d a t e of t h e award n o t i c e . The a c t i v a t i o n d a t e cannot b e r e t r o a c t i v e t o a d a t e p r i o r t o t h e d a t e of t h e Not ice o f Research Fe l lowship Award.

Conditions o f Auard Upon t e r m i n a t i o n of t h e f e l l o w s h i p t h e f e l low w i l l submit a comple te and d e f i n i t i v e r e p o r t of t h e f e l lowsh ip ass ignment i n c l u d i n g accomplishments , recommendations, and e v a l u a t i o n o f t h e suppor t ed a c t i v i t y . I f p o s s i b l e , a r e p o r t by t h e h o s t i n s t i t u t i o n and t h e nominat ing U.S. i n s t i t u ­t i o n w i l l b e o b t a i n e d . Fel lows are n o t e n t i t l e d t o v a c a t i o n s a s such , a l though they are e n t i t l e d t o t h e normal h o l i d a y p e r i o d s of t h e h o s t i n s t i t u t i o n .

Financial Arrangements Fel lowship t r a v e l funds , s t i p e n d s , and reimburse­ments t o h o s t i n s t i t u t i o n s are d i spensed d i r e c t l y by t h e sponsor ing i n s t i t u t i o n i n keeping w i t h N I H p o l i c y . Funds f o r t h i s purpose a r e provided through P u b l i c Hea l th S e r v i c e Fe l lowship Awards made t o t h e sponsor ing i n s t i t u t i o n f o r t h e i n d i v i d u a l f e l l o w s .

For Additional Information Contact:

S c h o l a r s and Fe l lowships Program Branch Fogar ty I n t e r n a t i o n a l Cen te r N a t i o n a l I n s t i t u t e s of Heal th Bethesda , Maryland 20014

N I H Guide f o r Grants and C o n t r a c t s V o l . 6, No. 10, May 18, 1977

PERSONNEL VACANCY

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A N N O U N C E M E N T

The National Institutes of Health invites nominations and applications for the position of Associate Director for Extramural Research and Training, NIH, who will serve as the principal advisor to the Director, NIH, on all matters relating to the substance, quality, and effectiveness of the NIH Extramural Programs. Candidates should have knowledge of the NIH programs and policies, an understanding of problems confronting institutions, and an appreciation of the major issues confronting biomedicine, the NIH, and the public.

Applicants should possess the Ph.D., M.D., or other professional degree, or equivalent, and have demonstrated achievement and stature in a biomedical, behavioral, or social science discipline. Demonstrated administrative and interpersonal skills are also required for interacting with Federal and non-Federal organizations.

Position is in a top U.S. Civil Service grade level or in the PHS Commissioned Corps. Letters of application o r nominations with curriculum vitae should be sent to the Chairman of the Search Committee:

Thomas E. Malone, Ph.D. National Institutes of Health Public Health Service Room 107, Building 1 Bethesda, Maryland 20014

Applications must be received by June 3, 1977, to be considered.

AN EQUAL OPPORTUNITY EMPLOYER

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CORRECTION - NCI CONSTRUCTION PROGRAM

Requests f o r no more than 50% F e d e r a l c o n s t r u c t i o n g r a n t s w i l l b e e f f e c t i v e February 1, 1978, r e c e i p t d a t e r a t h e r 1977, as s t a t e d on page 1 7 of Vo l . 6 , N I H Guide for Grants and Contracts.

COMPENSATION OF INJURED

RESEARCH SUBJECTS

f i n a n c i a l p a r t i c i p a t i o n i n N C I f o r a p p l i c a t i o n s submi t t ed f o r t h e t h a n t h e r e c e i p t d a t e of October 1, No. 9 , d a t e d A p r i l 26, 1977, of t h e

AVAILABILITY OF REPORT

A r e p o r t , i n c l u d i n g recommendations, from t h e HEW S e c r e t a r y ' s Task Force on t h e Compensation of I n j u r e d Research S u b j e c t s was p u b l i s h e d i n January 197 7 .

A d d i t i o n a l c o p i e s of t h i s p u b l i c a t i o n (HEW P u b l i c a t i o n Number OS-77-003) may b e o b t a i n e d from:

N a t i o n a l I n s t i t u t e s of Hea l th Room 1-B-58, Bu i ld ing 31 9000 R o c k v i l l e P i k e Bethesda, Maryland 20014

N I H Guide for Grants and C o n t r a c t s V o l . 6 , No. 10, May 18, 1 9 7 7 Page Seven

W MEDICAL SCHOOL PULMONARY

FACULTY TRAINING AWARD A N N O U N C E M E N T

1. Objective Under a u t h o r i t y of t h e N a t i o n a l Heart, Blood Vessel, Lung, and Blood A c t of 1972 (P.L. 92-423, Sec. 413a) as extended by t h e Hea l th Research and Heal th S e r v i c e s Amendments of 1976 (P.L. 94-2781, t h e D i v i s i o n o f Lung Diseases of t h e N a t i o n a l Heart, Lung, and Blood I n s t i t u t e announces a new compe t i t i on f o r N a t i o n a l Pulmonary F a c u l t y T r a i n i n g Awards. The o b j e c t i v e of t h e s e awards is t o s t r e n g t h e n e d u c a t i o n and r e s e a r c h i n pulmonary medicine a t s c h o o l s of medicine and o s t e o p a t h y i n t h e United S t a t e s which do n o t have f u l l y developed programs addres sed t o r e s p i r a t o r y d i s e a s e s . To accomplish t h i s g o a l t h e program:

e prov ides s u p p o r t f o r a t r a i n i n g environment a t medical c e n t e r s w i t h s t r o n g pulmonary e d u c a t i o n and r e s e a r c h programs,

e prov ides an o p p o r t u n i t y f o r j u n i o r f a c u l t y members from s c h o o l s w i sh ing t o s t r e n g t h e n t h e i r pulmonary academic programs t o o b t a i n e x t e n s i v e pulmonary t r a i n i n g a t medical c e n t e r s where t h e t r a i n i n g environment i s suppor t ed through t h i s program,

e prov ides l i m i t e d s a l a r y s u p p o r t t o j u n i o r f a c u l t y who have completed t h e t r a i n i n g program and who r e t u r n t o t h e i r s c h o o l s t o s t r e n g t h e n t h e r e s e a r c h and t r a i n i n g c a p a b i l i t y o f t h o s e s c h o o l s i n pulmonary medicine.

S i x t r a i n i n g s i tes have been e s t a b l i s h e d a t medical s c h o o l s w i t h s t r o n g , wel l -developed pulmonary r e s e a r c h and t r a i n i n g programs, adequa te numbers of h i g h l y t r a i n e d f a c u l t y i n c l i n i c a l and b a s i c departments concerned w i t h p r o b l e m s of pulmonary disease, and i n t e r e s t and c a p a b i l i t y t o p rov ide t r a i n i n g t o young p h y s i c i a n s and b a s i c s c i e n t i s t s who wish t o become pulmonary academicians. The c u r r e n t c e n t e r s are:

Johns Hopkins U n i v e r s i t y U n i v e r s i t y of C a l i f o r n i a , Los Angeles U n i v e r s i t y of C a l i f o r n i a , San Diego U n i v e r s i t y of C a l i f o r n i a , San F r a n c i s c o U n i v e r s i t y o f Oklahoma U n i v e r s i t y o f Texas

2 . Criteria for El ig ib i l i t y Domestic s c h o o l s of medicine o r o s t e o p a t h y t h a t (1) have f e w o r no f a c u l t y members engaged i n f u l l - t i m e t e a c h i n g , r e s e a r c h , and c l i n i c a l care i n pulmonary d i s e a s e and r e s p i r a t o r y d i s o r d e r s , ( 2 ) have l i t t l e o r no c a p a c i t y f o r t r a i n i n g young f a c u l t y members even when s u c c e s s f u l in r e c r u i t i n g them, a n d ( 3 ) w i l l p rov ide a f a c u l t y p o s i t i o n f o r any j u n i o r f a c u l t y member t r a i n e d under t h e Pulmonary F a c u l t y T r a i n i n g

W Award a t t h e end of t h e t r a i n i n g p e r i o d are e l i g i b l e t o app ly .

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The j u n i o r f a c u l t y member nominated f o r t r a i n i n g by t h e a p p l y i n g s c h o o l -m u s t be a p h y s i c i a n o r s c i e n t i s t w i t h a d o c t o r a l deg ree i n a h e a l t h -r e l a t e d f i e l d who (1) is a c i t i z e n of t h e United S t a t e s , a c i t i z e n n a t i o n a l o r admi t t ed f o r permanent r e s i d e n c e a t t h e t i m e of a p p l i c a t i o n ; ( 2 ) w i shes t o r e c e i v e e x t e n s i v e s p e c i a l i z e d t r a i n i n g i n pulmonary d i s e a s e o r r e s p i ­r a t o r y d i s o r d e r s , o r i n b a s i c mechanisms invo lved i n t h e s e ; (3) is committed t o r e t u r n , upon complet ion of t h i s t r a i n i n g , t o a f a c u l t y p o s i t i o n i n t h e s p o n s o r i n g s c h o o l ; and ( 4 ) h a s t h e background and p o t e n t i a l t o p r o f i t from t h e s p e c i a l i z e d t r a i n i n g .

The a p p l i c a n t i n s t i t u t i o n , t o g e t h e r w i t h t h e nominated f a c u l t y member, must p rov ide a t r a i n i n g p l a n which w i l l e n a b l e t h e f a c u l t y member t o r e t u r n t o t h e nominat ing s c h o o l w i t h a b r e a d t h of t r a i n i n g s u i t a b l e t o h i s o r h e r f u t u r e r o l e on t h e f a c u l t y . The j u n i o r f a c u l t y member a t t h e a p p l i c a n t i n s t i t u t i o n must a g r e e t h e d e s i g n a t e d t r a i n i n g c e n t e r s . member, who must t h e n r e t u r n t o s u p p o r t f o r two a d d i t i o n a l y e a r s p rov ide t i m e f o r t h e t r a i n e e t o

t o spend t h r e e y e a r s a t one o r more o f Fol lowing t h e t r a i n i n g , t h e f a c u l t y

t h e s p o n s o r i n g i n s t i t u t i o n , w i l l r e c e i v e from t h e D i v i s i o n o f Lung Diseases t o

i n i t i a t e a r e s p i r a t o r y d i s e a s e program a t t h e s p o n s o r i n g i n s t i t u t i o n . The s p o n s o r i n g i n s t i t u t i o n , f o r i ts p a r t , m u s t a g r e e t o p r o v i d e a f a c u l t y p o s i t i o n f o r t h e t r a i n e e f o r a minimum of t h r e e y e a r s a f t e r t h e t e r m i n a t i o n of t h e award.

App l i can t s may r e q u e s t up t o $25,000 f o r t h e j u n i o r f a c u l t y member's sa lary, a p p r o p r i a t e f r i n g e b e n e f i t s , and r o u n d - t r i p economy a i r fa re t o t h e T r a i n i n g Cen te r . No i n d i r e c t c o s t s are p e r m i t t e d u n t i l t h e f o u r t h y e a r of t h e award and t h e n a t a l l o w a b l e ra tes up t o b u t n o t t o exceed 8% of allow- llnr

a b l e d i r e c t c o s t s .

3. When and How to A p p l y A complete d e s c r i p t i o n of t h e program and g u i d e l i n e s f o r a p p l i c a t i o n s may be o b t a i n e d from:

John B . Mathis , Ph.D. D i v i s i o n of Lung Diseases N a t i o n a l Heart, Lung, and Blood I n s t i t u t e Room 6A-05 5333 Westbard Avenue Bethesda, Maryland 20016

Telephone: (301) 496-7668

An i n s t i t u t i o n i n t e r e s t e d i n s u b m i t t i n g a n a p p l i c a t i o n must forward a l e t t e r of i n t e n t t o t h e Na t iona l Heart , Lung, and Blood I n s t i t u t e by June 1 5 , 1977. Th i s l e t t e r w i l l n o t b e cons ide red a commitment t o a p p l y , b u t w i l l b e used t o estimate t h e number of p r o p o s a l s t o b e s u b m i t t e d .

A p p l i c a t i o n s f o r Pulmonary F a c u l t y T r a i n i n g Awards must be r e c e i v e d by t h e Na t iona l I n s t i t u t e s of Hea l th p r i o r t o August 1, 1977, f o r review by t h e Na t iona l Heart, Lung, and Blood Advisory Council i n February 1978. The r eques t ed beg inn ing d a t e f o r funding shou ld be J u l y 1, 1978.

I n s t r u c t i o n s f o r a p p l y i n g and a p p l i c a t i o n forms ( N I H 398) may be o b t a i n e d from t h e a d m i n i s t r a t i v e o f f i c e of t h e a p p l i c a n t i n s t i t u t i o n . I f n o t o t h e r - .e+

N I H Guide f o r Grants and C o n t r a c t s Vo l . 6, No. 10, May 18, 1977 Page Nine

w i s e a v a i l a b l e , form N I H 398 shou ld be r eques t ed from t h e O f f i c e of Gran t s I n q u i r i e s , D i v i s i o n o f Research G r a n t s , N I H , Bethesda, Maryland 20014.

4 . Review of Applications A p p l i c a t i o n s w i l l be reviewed i n i t i a l l y f o r t e c h n i c a l merit i n terms of t h e c r i t e r i a d e t a i l e d i n t h e program announce­ment and a p p l i c a t i o n g u i d e l i n e s . The review w i l l i n c l u d e an i n i t i a l assess­ment of t h e w r i t t e n p r o p o s a l and may i n v o l v e a n i n t e r v i e w w i t h t h e p r o s p e c t i v e t r a i n e e i n Bethesda, Maryland. The i n i t i a l review group w i l l recommend a p p l i c a n t s f o r c o n s i d e r a t i o n t o t h e N a t i o n a l Heart, Lung, and Blood Advisory Counci l .

5 . Coordination Procedures The program announcement and a p p l i c a t i o n g u i d e l i n e s d e s c r i b e t h e t r a i n i n g c a p a b i l i t i e s of each o f t h e s i x d e s i g n a t e d c e n t e r s . A p p l i c a t i o n s f o r Pulmonary Facu l ty T r a i n i n g Awards shou ld l i s t t h e j u n i o r f a c u l t y member's p r e f e r r e d t r a i n i n g s i t e and two a l t e r n a t e sites. The D i v i s i o n of Lung Diseases w i l l forward c o p i e s of approved a p p l i c a t i o n s t o t h e t r a i n i n g c e n t e r s . Upon n o t i f i c a t i o n by t h e t r a i n i n g c e n t e r s of a c c e p t a b l e a p p l i c a n t s , t h e D i v i s i o n of Lung Diseases w i l l f a c i l i t a t e t h e matching of j u n i o r f a c u l t y t r a i n e e s w i t h a v a i l a b l e p o s i t i o n s i n t h e p r e f e r r e d t r a i n i n g c e n t e r s .

W

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PULMONARY ACADEMIC AWARD A N N O U N C E M E N T

1. Objectives Under authority of the National Heart, Blood Vessel, Lung, and Blood Act of 1972 (P.L. 92-423, Sec. 413a) as extended by the Health Research and Health Services Amendments of 1976 (P.L. 94-2781, the Division of Lung Diseases, National Heart, Lung, and Blood Institute announces a national competition for Pulmonary Academic Awards, which have the purpose of stimulating development of a pulmonary curriculum in those schools which do not have one and strengthening and improving the pulmonary curriculum in those schools that do. Awards provide support to individual faculty members for their educational development, and for development and implementa­tion of an improved pulmonary curriculum. In making these awards, the Division of Lung Digeases is encouraging the development of superior pulmonary curricula that will attract outstanding students to pulmonary research and medical practice, and is stimulating the development of ongoing mechanisms at grantee institutions for continued improvement of pulmonary education. This latter goal is to be accomplished through the development of improved educational skills in faculty members with a responsibility for undergraduate and graduate education in pulmonary medicine.

2 . Criteria for the Award Competitive review for a pulmonary academic award will include assessment of both the sponsoring institution and the proposed awardee. The specific sponsoring institution must present plans to develop or improve the pulmonary educational program. The prospective awardee must agree to commit a minimum of 50% of his ( o r her) effort to developing, improving, and implementing a pulmonary curriculum and specify a program for developing those personal educational skills essential to improving the pulmonary curriculum.

3. Provisions of the Award Each school of medicine or osteopathy in the United States or its possessions and territories is eligible for a pulmonary academic award. However, awards will be limited to one for each eligible medical school, for a project period up to five years. Subject to availability of necessary funds, and consonant with the objectives of the Pulmonary Academic Award, the Division of Lung Diseases will provide funds on an annual basis for:

e

e

support for the awardee, who will devote a minimum of 50% effort to developing and implementing the pulmonary curriculum;

consultant fees for a limited number of experts in the areas of pulmonary diseases and medical education;

equipment necessary to develop the pulmonary curriculum;

supplies necessary to achieve the program's objectives;

travel to enable the awardee to develop his o r her educational skills and to meet with other awardees to exchange ideas, methods, and program evaluations;

Page Twelve

a s t i p e n d s , i n accordance w i t h N I H p o l i c i e s , f o r a l i m i t e d number of s t u d e n t s t o augment t h e i r pulmonary l e a r n i n g e x p e r i e n c e s d u r i n g an e l e c t i v e q u a r t e r i n t h e academic y e a r ; and

0 i n d i r e c t c o s t s , a c t u a l up t o , b u t n o t t o exceed , 8% of a l l o w a b l e d i r e c t c o s t s .

4 . When and How to A p p l y I n d i v i d u a l s i n t e r e s t e d i n app ly ing f o r a Pulmonary Academic Award shou ld o b t a i n a copy of t h e program announcement from:

John B. Math is , Ph.D. D i v i s i o n of Lung Diseases N a t i o n a l Heart, Lung, and Blood I n s t i t u t e Room 6A-05 5333 Westbard Avenue Bethesda , Maryland 20016

Telephone: (301) 496-7668

P r o s p e c t i v e a p p l i c a n t s must p r e s e n t a l e t t e r of i n t e n t , coun te r s igned by t h e Chairman of t h e i r r e s p e c t i v e academic depa r tmen t s , t o the N a t i o n a l Heart, Lung, and Blood I n s t i t u t e by June 15, 1977. This let ter w i l l n o t b e cons ide red a commitment t o apply b u t w i l l b e used t o estimate t h e number of p r o p o s a l s t o b e submi t t ed .

A p p l i c a t i o n f o r a Pulmonary Academic Award must b e r e c e i v e d by t h e N a t i o n a l I n s t i t u t e s of Hea l th p r i o r t o August 1, 1977, f o r review by t h e N a t i o n a l Heart, Lung, and Blood Advisory Counci l i n February 1978. The r e q u e s t e d beg inn ing d a t e f o r funding shou ld b e June 1, 1978.

I n s t r u c t i o n s f o r a p p l y i n g and a p p l i c a t i o n forms (NIH 398) may b e ob ta ined from t h e a d m i n i s t r a t i v e o f f i c e of t h e a p p l i c a n t i n s t i t u t i o n . I f n o t o t h e r -w i s e a v a i l a b l e , form NIH 398 shou ld be r eques t ed from t h e O f f i c e of Gran t s I n q u i r i e s , D i v i s i o n of Research G r a n t s , N I H , Be thesda , Maryland 20014.

5 . Review of Applications A p p l i c a t i o n s f o r Pulmonary Academic Awards w i l l b e a p p r a i s e d i n terms of t h e c r i t e r i a o u t l i n e d f o r t h e sponsor ing i n s t i t u t i o n and t h e awardee d e s c r i b e d i n t h e program announcement and a p p l i c a t i o n guide- l i n e s . The review w i l l i n c l u d e an i n i t i a l assessment of t h e w r i t t e n proposa l and may r e q u i r e an i n t e r v i e w w i t h t h e p r o s p e c t i v e awardee i n Bethesda, Maryland. The i n i t i a l review group w i l l recommend a p p l i c a n t s f o r c o n s i d e r a t i o n by t h e N a t i o n a l H e a r t , Lung, and Blood Advisory Counci l .

N I H Guide f o r G r a n t s and C o n t r a c t s V o l . 6, No. 10, May 18, 1977 Page T h i rt e e n

SPECIAL DENTAL RESEARCH AWARD A N N O U N C E M E N T

This announcement is a r e v i s i o n o f , and t h u s s u p e r s e d e s , t h e announcement con ta ined on page 15, Vol. 5 , No. 20, N I H Guide for Grants and Contracts.

The Nat iona l I n s t i t u t e of D e n t a l Research (NIDR) makes S p e c i a l Den ta l Research Awards (SDRA) t o p r o v i d e funds f o r young s c i e n t i s t s t o conduct independent i n v e s t i g a t i o n s d u r i n g t h e e a r l y s t a g e s o f t h e i r careers. Recen t ly t r a i n e d s c i e n t i s t s are encouraged t o s e e k g r a n t funds through t h i s award and make t h e i r c o n t r i b u t i o n s i n t h e expanding f i e l d of o r a l h e a l t h r e s e a r c h .

EZigibiZitx I n v e s t i g a t o r s w i t h no more than f o u r y e a r s of r e s e a r c h e x p e r i e n c e beyond complet ion of r e s e a r c h t r a i n i n g may app ly f o r an SDRA g r a n t . Persons who meet t h i s requirement may a p p l y even i f they ho ld a Research Career Development Award o r a N a t i o n a l Research S e r v i c e Award

. (NRSA) f o r I n d i v i d u a l P o s t d o c t o r a l Fe l lowsh ips , are t r a i n i n g under a n NRSA I n s t i t u t i o n a l G r a n t , o r are suppor t ed under t h e Minor i ty Biomedical Sc ience o r t h e Biomedical Research Support Programs. However, p r i n c i p a l i n v e s t i g a t o r s on r e g u l a r N I H r e s e a r c h g r a n t s are n o t e l i g i b l e f o r t h e s e S p e c i a l Den ta l Research Awards, n o r can t h e g r a n t s s u p p o r t t h e s i s r e s e a r c h .

Provisions A p p l i c a n t s may r e q u e s t a maximum of $25,000 d i r e c t c o s t s p e r y e a r , f o r each o f t h r e e y e a r s . O f t h e s e funds , as much as $15,000 may be r eques t ed t o pay no more than 50% of t h e p r i n c i p a l i n v e s t i g a t o r ' s s a l a r y (commensurate w i t h p e r c e n t of e f f o r t ) . Up t o $10,000 can b e budgeted f o r such items as s u p p l i e s , t e c h n i c a l s u p p o r t , t r a v e l , and p u b l i c a t i o n s . A l l o t h e r r e g u l a t i o n s and p o l i c i e s governing NIH-supported r e s e a r c h p r o j e c t g r a n t s , i n c l u d i n g c o s t - s h a r i n g r equ i r emen t s , app ly t o t h e s e g r a n t s .

AppZication Procedures A p p l i c a n t s shou ld use t h e r e g u l a r r e s e a r c h g r a n t a p p l i c a t i o n (NIH 398) and w r i t e "Spec ia l Den ta l Research Award" on t h e top of the face page. Applications are a v a i l a b l e a t i n s t i t u t i o n a l c e n t r a l a p p l i c a t i o n c o n t r o l o f f i c e s ( s e e Vol. 2 , No. 8, October 26 , 1973) . The d e a d l i n e s f o r submission of a p p l i c a t i o n s are J u l y 1, November 1, and March 1. A p p l i c a t i o n s w i l l b e c o m p e t i t i v e l y reviewed by D i v i s i o n of Research Grants s t u d y s e c t i o n s and t h e N a t i o n a l Advisory Dental Research Council .

When t h e SDRA g r a n t p e r i o d t e r m i n a t e s , t h e i n v e s t i g a t o r may a p p l y f o r a renewal of t h e g r a n t f o r a n a d d i t i o n a l p e r i o d , b u t t h e g r a n t w i l l no l o n g e r b e cons ide red a s p e c i a l award. I n s t e a d , renewal a p p l i c a t i o n s w i l l be cons ide red as competing c o n t i n u a t i o n s of r e g u l a r r e s e a r c h g r a n t s w i th -o u t t h e f i n a n c i a l r e s t r i c t i o n s of t h e s p e c i a l g r a n t .

Areas of Interest S p e c i a l Den ta l Research Awards s u p p o r t m e r i t o r i o u s b a s i c o r c l i n i c a l r e s e a r c h p r o j e c t s d i r e c t e d toward t h e improvement o f o r a l and d e n t a l h e a l t h . The I n s t i t u t e encourages i n v e s t i g a t i o n s on P e r i o d o n t a l Disease,- Denta l Caries, and Oral S o f t T i s s u e Diseases, i n c l u d i n g

Page Fourteen

he rpes s implex , aphthous u l c e r s , o r a l tumors , and o t h e r l e s i o n s . For example, t h e r e c e n t f i n d i n g s t h a t s p e c i f i c b a c t e r i a may c a u s e c e r t a i n forms of p e r i o d o n t a l d i s e a s e need conf i rma t ion i n o t h e r p o p u l a t i o n groups ; and comprehensive immunology s t u d i e s shou ld b e done on both an ima l s and humans to e l u c i d a t e t h e h o s t r e sponse p a t t e r n t o each of t h e suspec ted pathogens. S ince d e n t a l caries r e q u i r e s b a c t e r i a l f e r m e n t a t i o n of food-s t u f f s on a s u s c e p t i b l e t o o t h , caries r e s e a r c h focuses on combating t h e b a c t e r i a , modifying t h e d i e t , and i n c r e a s i n g t h e r e s i s t a n c e of t h e t o o t h . E s p e c i a l l y i n o r d e r are p r o j e c t s on a n t i c a r i e s v a c c i n e development and on t h e e f f i c a c y of a n t i m i c r o b i a l a g e n t s . There is a l s o a need f o r p r o p o s a l s r e l a t e d t o O r a l - f a c i a l Growth and Development, Malocc lus ion , C r a n i o f a c i a l Anomalies, and Acquired Dis f igurement . Such p r o j e c t s may b e b a s i c i n n a t u r e , employing l a b o r a t o r y approaches , o r may c o n s i s t of a p p l i e d r e s e a r c h i n v o l v i n g an imals o r humans. I n t h e f i e l d of O r o f a c i a l P a i n , t h e r e i s a need f o r s t u d i e s of s enso ry r e sponses , f e a r and a n x i e t y , and p a i n f u l c o n d i t i o n s such a s t r i g e m i n a l n e u r a l g i a . P r o j e c t s on t h e S o c i a l and Behaviora l a s p e c t s of o r a l d i s e a s e s are a l s o i n v i t e d . Two o t h e r impor t an t areas of i n q u i r y are t h e f u n c t i o n of S p e c i f i c C o n s t i t u e n t s of S a l i v a r y S e c r e t i o n s and t h e r e l a t i o n s h i p of N u t r i t i o n t o o r a l h e a l t h and d i s e a s e . O f immediate importance t o t h e N I D R i s t h e improvement of Denta l F i l l i n g M a t e r i a l s , Adhesive S e a l a n t s , M a x i l l o f a c i a l P r o s t h e t i c Materials, and t h e development of e f f e c t i v e Tooth Implan t s .

I n q u i r i e s r e g a r d i n g t h i s program may b e addres sed t o D r . Anthony A. R izzo , Extramural Programs, N a t i o n a l I n s t i t u t e of Denta l Research , N I H , Room 519, Westwood Bu i ld ing , Bethesda , Maryland 20014; t e l ephone : ( 301) 496-7784.

41.5. GOVERNMENT PRINTING OFFICE. 197- 241-639/5 1-3

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