URRIIINNAAAAAARRRR

Embed Size (px)

Citation preview

  • 8/7/2019 URRIIINNAAAAAARRRR

    1/19

    1

  • 8/7/2019 URRIIINNAAAAAARRRR

    2/19

    2

  • 8/7/2019 URRIIINNAAAAAARRRR

    3/19

    1. Regulating blood volume and pressure

    2. Regulating plasma concentrations of sodium,potassium, chloride and other ions

    3. Stabilising blood pH

    4. Conserving nutrients

    5. Detoxifying poisons (with the liver)

    3

  • 8/7/2019 URRIIINNAAAAAARRRR

    4/19

    Kidneys

    Ureters

    Urinary bladder Urethra

    4

  • 8/7/2019 URRIIINNAAAAAARRRR

    5/19

    CT abdomen with contrast MRI coronal abdomen

    5

  • 8/7/2019 URRIIINNAAAAAARRRR

    6/19

    3 layers of connectivetissue:

    Inner layer- Renal capsule

    Middle layer- Adiposecapsule

    Outer layer-Renal fascia

    6

    Renal cortex

    Retroperitoneal space

  • 8/7/2019 URRIIINNAAAAAARRRR

    7/19

    Hilum is located onthe medial surface

    7

    10 cm

    5.5cm

    3cm

  • 8/7/2019 URRIIINNAAAAAARRRR

    8/19

    8

    Renal pyramids

    Renal papilla

    Renal Columns

    Renal Lobe

  • 8/7/2019 URRIIINNAAAAAARRRR

    9/19

    9

  • 8/7/2019 URRIIINNAAAAAARRRR

    10/19

    10

  • 8/7/2019 URRIIINNAAAAAARRRR

    11/19

    11

    1. Proximal convoluted

    tubule

    2. Descending loop of

    Henle

    3. Ascending loop ofHenle

    4. Distal convoluted

    tubule

    5. Collecting duct

  • 8/7/2019 URRIIINNAAAAAARRRR

    12/19

    12

    Blood enters the kidney

    through the renal artery at

    the site of the hilum

    The renal artery divides in

    to ever smaller arteries and

    arterioles

    Afferent arterioles take blood to

    the glomerulus to be filtered

    Once blood is filtered

    efferent arterioles take blood

    away from the glomerulus

    The glomerulus is a

    network of capillaries

    which filters the blood

    Products which are filtered out:

    water, mineral salts, amino acids,

    glucose, hormones, urea, toxins

    Products which do not filter

    and remain in the blood:

    Leukocytes, erythrocytes,

    platelets, plasma proteins

    The filtered substances

    move into the proximal

    convoluted tubule

    The PCT is concerned with

    reabsorption- organic nutrients are

    reabsorbed and water follows

    because there is a concentration

    gradient

    The remaining filtrate moves

    into the descending loop of

    henle. This is lined with thin

    cells so water moves out

    Because water has been

    reabsorbed the concentration

    of the filtrate is not very high

    The walls of the ascending loop

    of henle are lined with thicker

    cells, so water cant pass in or

    out. Instead sodium and

    chloride is pumped out actively

    The filtrate now enters the

    distal convoluted tubule- is it

    now only 20% of what it

    originally was.In the DCT the volume and

    composition of the filtratecan be adjusted but this is

    controlled by hormones

    From the DCT the filtrate now

    passes into the collecting duct.

    A number of other nephrons join

    up to the cleectig duct which

    travels through the medulla to therenal papilla wher the filtrate is

    emptied in the minor calyx

    - minor calyces join up to

    make a major calyx

    2- major calyces join up

    to form the renal pelvisThe renal pelvis joins the

    ureter at the hilum

    The ureter transport the

    filtrate/urine from the kidney

    to the bladder

  • 8/7/2019 URRIIINNAAAAAARRRR

    13/19

    3 processes involved in the formation of urine.

    Simple filtration

    Selective reabsorbtion Hormonal control-

    Parathyroid hormone, calcitonin

    Anti diuretic hormone

    Aldosterone

    Secretion

    13

  • 8/7/2019 URRIIINNAAAAAARRRR

    14/19

    Superiorly Continuous with the renal

    pelvis

    Inferiorly

    Pass through the abdominalcavity, behind theperitoneum, infront of thepsoas muscle, into thepelvic cavity ehere theyenter the posterior wall ofthe bladder

    25-30 cm in length

    14

  • 8/7/2019 URRIIINNAAAAAARRRR

    15/19

    3 layers of tissue

    Outer layer Fibrous tissue

    Middle layer Muscle

    Inner layer

    Epithelium

    15

  • 8/7/2019 URRIIINNAAAAAARRRR

    16/19

    16

  • 8/7/2019 URRIIINNAAAAAARRRR

    17/19

    3 layers

    Outer layer Loose connective tissue

    Middle layer Smooth muscle and

    elastic fibres

    Inner layer Lined with transitional

    epithelium

    17

  • 8/7/2019 URRIIINNAAAAAARRRR

    18/19

    Extends from thebase of the bladderto the outside world.

    Anatomicaldifferences meanthat male and femaleurethras are

    different. Female: 4cmlong

    Male: 14cmlong

    18

  • 8/7/2019 URRIIINNAAAAAARRRR

    19/19

    Muscle layer

    Submucosa layer

    Mucosa

    19