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Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

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Page 1: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Urines and Smears

Alan ChengUNC Medicine Upper Level Conference

7/15/09

Page 2: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Epithelial cell

Transitional cellAbove, clue cell. Below, normal.

http://www.medicine.uiowa.edu/cme/clia/modules.asp?testID=20

Page 3: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Normal RBC’s

Crenated RBC’s from elevatedSG or PH.

Normal RBC’s

Dysmorphic RBC’s (mickey mouse)http://www.medicine.uiowa.edu/cme/clia/modules.asp?testID=20http://www.agora.crosemont.qc.ca/urinesediments/Imdoceng/d13d001.htm

Page 4: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Mixed bacteria

trichomonad

B – yeast, C - RBC

http://www.medicine.uiowa.edu/cme/clia/modules.asp?testID=20

Page 5: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

http://www.med.illinois.edu/internalMed/residency/edmod/mod1/casts.htm; http://www.agora.crosemont.qc.ca/urinesediments/Imdoceng/d19d002.htm

Hyaline casts

WBC cast

RBC cast

Granular cast vs WBC cast

Page 6: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

RBC casts

WBC cast

http://www.meddean.luc.edu/lumen/MedEd/MEDICINE/PULMONAR/Renal/Atlas/urineatlas_f.htm

Page 7: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

http://meded.ucsd.edu/isp/1994/im-quiz/urine.htm

Uric acid crystals

Calcium oxalate

Triple phosphate or Struvite

Cysteine stones

Calcium oxalate

Page 8: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

sperm

http://meded.ucsd.edu/isp/1994/im-quiz/urine.htm

cotton

Page 9: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Triple phosphate

Uric acid

http://www.meddean.luc.edu/lumen/MedEd/MEDICINE/PULMONAR/Renal/Atlas/urineatlas_f.htm

Page 10: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

A = renal tubular cellB = WBC

A = renal tubular cellB = oval fat body

oval fat body

http://meded.ucsd.edu/isp/1994/im-quiz/urine.htmhttp://www.meddean.luc.edu/lumen/MedEd/MEDICINE/PULMONAR/Renal/Atlas/urineatlas_f.htm

Page 11: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Now on to heme…

Page 12: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Normal smear

Plasma cell

lymphocyte

Page 13: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

neutrophilMonocyte

Basophil Neutrophil and eosinophil

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 14: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

reticulocyte

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 15: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Acanthocyte (spur cell)-Liver disease-Asplenia

Echinocyte (burr cell)-(Liver or) Renal disease

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 16: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Howell Jolly bodiesBasophilic Stippling

Nucleated RBCPappenheimer bodies

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 17: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Malaria

Auer Rods, AML M3

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 18: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Heinz body

Rouleaux (stack of coins)http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 19: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

elliptocyte

spherocyte

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 20: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

schistocyte

Teardrop cell

Sickle cellshttp://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 21: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

Target cell – increase in membrane:volume ratio-Asplenia- Thalassemia- Hemoglobinopathies- Liver disease- Iron deficiency

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 22: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

normal

macrocytosis

Microcytic, hypochromic

http://www.healthsystem.virginia.edu/internet/hematology/hessidb/normal-hematopoietic-cells.cfm

Page 23: Urines and Smears Alan Cheng UNC Medicine Upper Level Conference 7/15/09

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