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Title Prof./Dr./Mr./Ms.Dr.

FirstName Amita LastName Gupta Photograph

Designation AssociateProfessor

Department Biochemistry

Address(Campus) UniversityofDelhiSouthcampus,NewDelhi110021

(Residence) C‐1/1478,VasantKunj,NewDelhi110070

PhoneNo(Campus) 91‐11‐24114172

Mobile 91‐9811509609

Fax 91‐11‐24115270

Email amitagupta@south.du.ac.in

Web‐Page

EducationSubject Institution Year DetailsPh.DBiochemistry UniversityofDelhi 2001 Thesistopic:Genetically

engineeredrecombinantantibodyfusionproteinsforthedetectionofHumanimmunodeficiencyvirus(HIV)

M.ScBiochemistry UniversityofDelhiSouthcampus 1995 B.ScBiochemistry UniversityofDelhi 1993 CareerProfileOrganisation/Institution Designation Duration RoleDepartmentofBiochemistry,UniversityofDelhiSouthcampusNewDelhi

Scientist 2000‐2002 Research

DepartmentofBiochemistry,UniversityofDelhiSouthcampusNewDelhi

Lecturer(ad‐hoc) 2002‐2006 TeachingandResearch

DepartmentofMicrobiology,UniversityofDelhiSouthcampusNewDelhi

AssistantProfessor 2006‐2014 TeachingandResearch

DepartmentofBiochemistry,UniversityofDelhiSouthcampusNewDelhi

AssociateProfessor 2014‐Present TeachingandResearch

ResearchInterests/SpecializationResearchinterests‐Infectiousdiseasebiology;understandinghost‐pathogeninteraction;modulationofhostcelldeath;identificationofnoveldrugtargetsfornewdrugdevelopment;pathogenphysiologyanddevelopmentofpersistence,multi‐drugtolerantphenotype,methodsfordetectionofdrug‐resistantMycobacteria,molecularandimmunodiagnosticsforinfectiousdiseases.Specialisation‐RecombinantDNAtechnology,Functionalgenomicsofpathogenicmicroorganisms,ClinicalMicrobiology,Antibody/ProteinEngineering,Recombinantproteinproduction

UniversityFacultyDetailsPageonDUWeb‐site

(PLEASEFILLTHISINANDSUBMITAHARDCOPYANDSOFTCOPYONCDALONGWITHYOURPERIODICINCREMENTCERTIFICATE(PIC))

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TeachingExperience(Subjects/CoursesTaught)2002‐2007 Metabolism,ProteinsandEnzymes,Enzymekinetics,Expressionsystemsandproductionstrategiesfor

recombinantproteins2006‐2009AnimalVirology,Productionofrecombinantproteins,ApplicationsofRecombinantDNAtechnologyin

microbiology,2009‐tilldateMolecularBiology2011‐tilldateImmunologyGuidedM.Scstudentsforpracticals.GuidedM.Scstudentsforone‐yeardissertationwork.ResearchGuidance

1. SupervisionofawardedDoctoralThesis‐One2. SupervisionofDoctoralThesis,underprogress‐Three3. SupervisionofawardedM.Phildissertations‐Two4. SupervisionofM.Phildissertations,underprogress‐None

Honors&Awards1. 2015,Visitor’sawardforinnovationbyHon’blePresidentofIndia.

2. 2010,SeniorInnovativeYoungBiotechnologistAward(IYBA)byDepartmentofBiotechnology,MinistryofScienceand

Technology,Govt.ofIndia

3. 2007,IndianNationalScienceAcademy(INSA)YoungScientistAwardinthefieldofMedicalSciencesfortheyear2006.4. 2006,InnovativeYoungBiotechnologistAward(IYBA)2005byDepartmentofBiotechnology,MinistryofScienceand

Technology,Govt.ofIndia.5. 2005,ShakuntalaAmirChandAward‐2003ofIndianCouncilofMedicalResearch(ICMR),GovernmentofIndia.6. 2005,WIPO(WorldIntellectualPropertyOrganization,Geneva)GoldMedalfor“BestInventionoftheYear2004”for

inventing“On‐siteDetectionofHIV(AIDS).7. 2004,Prof.B.K.BachhawatMemorialYoungScientistlectureawardofTheNationalAcademyofSciences,India.8. 2004,NationalResearchDevelopmentCorporation(NRDC,DSIR,MinistryofScience&Technology,9. GovernmentofIndia)awardforinventing“On‐siteDetectionofHIV(AIDS)”10. 2003,awardedDr.D.L.SrivastavaYoungScientistAwardbySocietyofBiologicalChemists(India).11. 2003,awardedYoungScientistAward(NewBiologySection)byIndianScienceCongressAssociation.12. 2001,awardedOutstandingYoungScientistPrizefortheyear2001byInternationalBusinessCommunications,USA.13. 1995,awardedgoldmedalforsecuringfirstpositioninDelhiUniversityinM.Sc.(Biochemistry).Publications(LASTFIVEYEARS)Books/MonographsYearofPublication

Title Publisher Co‐Author

2005

PhageDisplay:Amolecularfashionshow.Manuscriptinbookentitled"Phages:TheirRoleinBacterialPathogenesisandBiotechnology"

AmericanSocietyofMicrobiology(ASM)

Oppenheim,AV.K.Chaudhary

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InIndexed/PeerReviewedJournalsYearofPublication

Title Journal Co‐Author

1999 AsimplifiedGene‐fragmentPhageDisplaysystemforepitopemapping

BiotechniquesVol27,Pg328‐334

Gupta,S.,Arora,K.,Sampath,A.Singh,S.Chaudhary,V.K

2000 Gag‐derivedproteinsofHIV‐1isolatesfromIndianpatients:cloning,expression,andpurificationofp24ofB‐andC‐subtypes

ProteinExpressionPurificationVol19Pg321‐328

Gupta,S.,Arora,K.,Chaudhary,V.K

2001 Gag‐derivedproteinsofHIV‐1isolatesfromIndianpatients:cloning,expression,andpurificationofp17ofB‐andC‐subtypes

ProteinExpressionPurificationVol21Pg378‐385

Gupta,S.,Arora,K.,Chaudhary,V.K

2001 MappingofHIV‐1Gagepitopesrecognizedbypolyclonalantibodiesusinggene‐fragmentphagedisplaysystem

PrepBiochemBiotechnolVol31Pg185‐200

Gupta,S.,Arora,K.,Sampath,A.,Singh,S.S.,Chaudhary,V.K

2001 Recombinantfusionproteinsforhaemagglutination‐basedrapiddetectionofantibodiestoHIVinwholeblood.

JImmunolMethodsVol256Pg121‐140

Gupta,S.,Chaudhary,V.K

2002 Expression,purificationandcharacterizationofananti‐RBCFab‐p24fusionproteinforhaemagglutinationbasedrapiddetectionofantibodiestoHIVinwholeblood.

ProteinExpressionPurificationVol26Pg162‐170.

Chaudhary,V.K

2003 Whole‐BloodAgglutinationAssayForOn‐SitedetectionofHumanImmunodeficiencyVirusinfection.

J.Clin.Micrbiol.Vol41(7)Pg2814‐2821

Chaudhary,V.K

2003 HighDensityFunctionalDisplayofProteinsonBacteriophageLambda

J.Mol.Biol.,Vol334(2)Pg241‐254

MasanoriOnda,IraPastan,SankarAdhya,andVijayK.Chaudhary

2005 Expressionandpurificationofrecombinant38‐kDaandMtb81antigensofMycobacteriumtuberculosisforapplicationinserodiagnosis

ProteinExpressionPurification40:169‐176

Chaudhary,V.K.,Kulshreshta,A.,Gupta,G.,Verma,N.,Kumari,S.,Sharma,S.K.,AnilK.Tyagi.

2005 Serogroup‐reactiveandtype‐specificdetectionofbluetonguevirusantibodiesusingchickenscFvsininhibitionELISAs.

JVirolMethodsVol129(1)Pg31‐39

FehrsenJ,vanWyngaardtW,MashauC,PotgieterAC,ChaudharyVK,JordaanFA,duPlessisDH

2005 ExpressionandpurificationofrecombinantantigensofMycobacteriumtuberculosisforapplicationinserodiagnosis.

ProteinExpressionPurificationVol44Pg75‐85.

AbhishekKulshreshtha,NitinVerma,S.K.Sharma,AnilK.TyagiandV.K.Chaudhary

2006 HIVDiagnostics:SavingLives,SlowingThePandemic. Proc.IndianNatl.

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Acad.Sci.Vol29Pg1‐15

2006 BifunctionalrecombinantfusionproteinsforrapiddetectionofantibodiestobothHIV‐1andHIV‐2inwholeblood.

BMCBiotechnologyVol6Pg39

V.K.Chaudhary

2009 Killingactivityandrescuefunctionofgenome‐widetoxin‐antitoxinlociofMycobacteriumtuberculosis.

FEMSMicrobiolLett290:45–53.

2009201220122013201320132014201420142015

Directedevolutionofananti‐humanredbloodcellantibody.IntraviralproteininteractionsofChandipuravirusMappinginteractionsofChikungunyavirusnonstructuralproteinsArobustandefficientmethodfortheisolationofDNA‐free,pureandintactRNAfromMycobacteriumtuberculosisANovelHelperPhageEnablingConstructionofGenome‐ScaleORF‐EnrichedPhageDisplayLibrariesElucidatingtheinteractingdomainsofchandipuravirusnucleocapsidproteinAnewmicroarrayplatformforwhole‐genomeexpressionprofilingofMycobacteriumtuberculosisRapidrestrictionenzyme‐freecloningofPCRproducts:ahigh‐throughputmethodapplicableforlibraryconstructionSmallscaleexpression,solubilization,andcharacterizationofChikungunyavirusstructuralproteinsHost‐pathogeninteractomeanalysisofChikungunyavirusenvelopeproteinsE1andE2

mAbs.1(3)268‐280ArchVirol.157(10):1949‐57VirusRes.169(1):231‐6Journalofmicrobiologicalmethods93:198‐202PLoSOne,8(9):e75212AdvVirol,2013:594319J.MicrobiolMethods,97:34‐43PLoSOne,9(10):e111538AsianJournalofPharmaceuticalandClinicalResearch,7(5):268‐271Virusgenes50,200‐209

V.K.Chaudhary,andR.BhatKumarK,RanaJ,SreejithR,GabraniR,SharmaSK,ChaudharyVK,GuptaSSreejithR,RanaJ,DudhaN,KumarK,GabraniR,SharmaSK,VratiS,ChaudharyVK,GuptaSBalajiV,GuptaNN.Shrivastava,P.Grover,A.Singh,K.Mathur,V.Verma,C.Kaur,andV.K.ChaudharyKumar,K.,S.Rajasekharan,S.Gulati,J.Rana,R.Gabrani,C.K.Jain,S.Gupta,V.K.ChaudharyVenkataraman,B.,M.VasudevanV.K.Chaudhary,N.Shrivastava,P.Grover,V.Verma,C.Kaur,andShilpiDasN.Dudha,J.Rana,R.Gabrani,V.K.Chaudhary,S.GuptaDudha,N.,Rana,J.,Rajasekharan,S.,Gabrani,R.,Chaudhary,V.K.,andGupta,S

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201520172018

HostinteractionsofChandipuravirusmatrixproteinCo‐expressionnetworkanalysisoftoxin‐antitoxinlociinMycobacteriumtuberculosisrevealskeymodulatorsofcellularstress.Biotintaggedproteins;ReagentsforefficientELISA‐basedserodiagnosisandphagedisplay‐basedaffinityselection

Actatropica149,27‐31SciRep,7(1),5868.PlosOne13(1)e0191315

Rajasekharan,S.,Kumar,K.,Rana,J.,Chaudhary,V.K.,andGupta,S.Gupta,A.,Venkataraman,B.,Vasudevan,M.,&GopinathBankar,K.V.Verma,C.Kaur,P.Grover,andV.K.Chaudhary

Articles

ConferencePresentationsPresentationatBanarasHinduUniversityatInternationalConferenceonBacteriophagesinRiverGanga(2017)PresentationatUniversityofHyderabadonTAloci(2017)PresentationatBhaskaracharyaCollegeofAppliedSciencesonMicrobialGenomics(2017)PresentationatUniversityofHyderabadunderGIANWorkshoponAntibodyEngineering(2016)PresentationatMicroarrayworkshopatAIIMS,NewDelhi(2013)PresentationatInternationalTBsymposiumatICGEB,NewDelhi(2009)PresentationatGordonResearchConferenceonTuberculosisDrugDevelopmentatOxford,UK(2007)PresentationatOnderspoortVeterinaryInstitute,Pretoria,RepublicofSouthAfrica(2003)Presentationatthe102ndGeneralMeetingofAmericansocietyofMicrobiology(ASM)atSaltLakeCity,USA(2002)PresentationatIBCsInternationalconferenceonAntibodyEngineeringatSanDiego,California,USA(2001)PresentationatIBCsfifthBiomolecularDiversityConferenceheldatWaltham,Massachuesetts,USA(2000)TotalPublicationProfileoptionalBooksOnechapter

InIndexed/PeerReviewedJournalsTwentysevenpublicationsandEightpatents

Articles

ConferencePresentationsTwelve

PublicService/UniversityService/ConsultingActivityMemberofBoardofResearchStudiesofFacultyofInterdisciplinaryandAppliedSciencesMemberofFacultyofInterdisciplinaryandAppliedSciences

ProfessionalSocietiesMembershipsLifememberofSocietyofBiologicalChemists(India).LifememberofIndianScienceCongressAssociationLifememberofAssociationofMicrobiologistsofIndia.

Projects(MajorGrants/Collaborations)• Genome‐widecloning,expressionandpurificationoftoxinandantitoxinproteinsofMycobacteriumtuberculosis

anddevelopmentofreagentsandstudyingthephysiologicalroleoftheseproteinsFundingAgency:DBT.Duration:March2007‐Feb2010Amountsanctioned:80.0lacs

• Antitoxin‐ToxinlociofMycobacteriumtuberculosis:IdentificationandBiochemicalCharacterization.FundingAgency:DBT.Duration:Apr2010‐Mar2013Amountsanctioned:1crore

• AsystemforenhancedproductionofrecombinantproteinsinMycobacteria.FundingAgency:DST.Duration:Jan2011‐Dec2013Amountsanctioned:42.0lacs

• IdentificationandcharacterizationofPromotersofToxinAntitoxinlociinMycobacteriumtuberculosisFundingAgency:CSIR.Duration:Oct2014‐Sept2017Amountsanctioned:35.0lacs

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• UnderstandingtheroleofRv1955‐Rv1956Toxin‐antitoxin(TA)locusofM.tuberculosisinpathogenbiology.FundingAgency:DBT.Duration:Aug2016‐July2019Amountsanctioned:53lacs

• Identificationofmycobacterialproteinsandnovelantigenicepitopeshavingimmunodiagnosticpotentialanddevelopmentofreagentsforpointofcaretestfortuberculosis.FundingAgency:DBT.Duration:Feb2018‐Feb2021Amountsanctioned:55lacs

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