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UK-INDIA EDUCATION & RESEARCH INITIATIVE
1. Title of the Project: Effect of cation substitution on the structure and biocompatibility of ionomer glasses
and glass ceramics (Website: www.iitk.ac.in/UKIERI_biomaterials/)
2. UKIERI Award letter number & date: DST/UKIERI/SA/P-23/09, dated 01/01/2009
3. Names, affiliations and e-mail addresses of the Principal Investigators from Partnering Institutions:
Indian PI: U.K. PI:
Dr. Bikramjit Basu Department of Materials Science & Engineering IIT-Kanpur, India E-mail: [email protected]
Dr. Artemis Stamboulis School of Materials & Metallurgical Engineering University of Birmingham,UK E-mail: [email protected]
6. Executive Summary: This research project was initiated at Indian side in January 2009 with the overall objective to combine the
cutting edge technologies of fabrication and testing of materials science with the knowledge of biological
sciences in order to develop ionomer glass-ceramic based implant materials for the purpose of the
enhancement of public health. The collaboration between Dr. Bikramjit Basu as Indian principal investigator
and Dr. Artemis Stomboulis as UK principal investigator as well as among their co-investigators is a true
demonstration of synergistic flow and utilization of scientific concepts, technological ideas and expertise in
the emerging area of biomaterials. With ten exchange visits of researchers as well as PIs, the DST-UKIERI
sponsored project has been successful in accomplishing the following major research outcome:
(a) demonstration and feasibility of novel spark plasma sintering in developing glass ionomers with a
good combination of mechanical properties,
(b) in vitro cytocompatibility evaluation to show good compatibility with L929 fibroblast cells,
(c) in vivo biocompatibility assessment in rabbit model to demonstrate neobone formation as well as
osseointegration property,
(d) EXAFS evaluation of fine scale compositional analysis of bone/implant interface.
In addition to meeting the stated objectives of the projects, some initiative on polymer based glass-ionomer
cement (GIC) was taken up and preliminary results on processing and characterization of GIC are also
summarized in this report. Apart from research outcome, Indian PI and Co-PIs visited a number of
institutions in UK, apart from partnering institutions, and delivered seminars to disseminate the outcome of
this project as well as to explore the possibility of future research collaboration in the field of biomaterials.
The summary of activities are available on the website (http://www.iitk.ac.in/UKIERI_biomaterials).
Photo taken during the presentation by Prof. Basu (top) and the kick-off meeting (bottom) of the UKIERI project at University of Warwick, UK in May, 2009
Photo taken during the review meeting at University of Birmingham on 5th February, 2010
Photo taken during the review meeting at University of Kent, UK on 8th February, 2010
