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Making a Difference RESEARCH THE UNIVERSITY OF GEORGIA

UGA Research 2014

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An overview of the UGA research enterprise

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Page 1: UGA Research 2014

Making a DifferenceRESEARCH

THE UNIVERSITY OF

GEORGIA

Page 2: UGA Research 2014

HHS (including NIH) 43%

NSF 23%

USDA 13%

Energy 9%

Other 12%

BY FEDERAL AGENCY

FY14 Sponsored Research Expenditures

Technology Transfer

UGA Research

130+ Startup companies

1978-2014

Top 5 Among U.S. universities

for license agreements for 7th consecutive year

Source: FY13 AUTM survey data

Products reached the market 1978-2014

525+

Sponsored Research Expenditures

Total

FY12

FY12 FY13 FY14

FY13 FY14

Federal

Licensing Revenues

As the state’s most comprehensive research institution, the University of Georgia is a major driver of economic and workforce development, catalyzing effective public/private partnerships that support industry, create new businesses, generate new jobs, and train the college-educated workforce of tomorrow.

The discoveries made by UGA researchers create unique opportunities to improve lives in Georgia and beyond. UGA is a top partner for industry, ranking among the best U.S. universities for licensing activity. More than 525 diverse products — from pharmaceuticals to peanuts and from poultry vaccines to education tools — are now in the marketplace.

Reported in millions of dollars

FY12 & 13 include federal American Recovery and Reinvestment Act funds.

Reported in millions of dollars

Agronomic Crops 40%

Pharma/Biotech 32%

Turfgrass/Ornamentals 16%

Horticultural Food Crops 7%

Engineering/Other 5%

FY14 Product Categories

TOP FIVE

Federal 84%

Non-profits 9%

State & Local 4%

Industry 3%

BY SPONSOR

TYPE

$157.1

$7.5 $8.3 $6.6

$133.1 $149.1 $142.8$126.2 $120.4

Page 3: UGA Research 2014

HHS (including NIH) 43%

NSF 23%

USDA 13%

Energy 9%

Other 12%

UGA Research: Changing how we understand our world UGA research harnesses intellectual power, curiosity and passion to address the vital challenges facing our world: health and healthy communities, energy and environmental sustainability, and security.

Averting Pandemics

UGAisapartnerwithEmoryUniversityinoneof fivefederalCentersof ExcellenceforInfluenzaResearch and Surveillance funded by the National Institute for Allergy and Infectious Diseases. The goals of the initiative, launched in 2007, are to provide the federal government with information, public health tools,andstrategiestocontrolandlessentheimpactof epidemicinfluenzaandtheincreasingthreatof pandemicinfluenza.Intheeventof apublichealthemergencyinvolvingtheemergenceandspreadof aninfluenzapandemicinhumans,thenetworkof centerswillbeonthefrontlinesof publichealthresponse.

Biomass to Biofuel

UGA has the largest university contribution to the BioEnergy Science Center (BESC), a nationwide consortium of universities, federal labs, and companies that the U.S. Department of Energy has funded at $250 million over 10 years to help make biofuels a cost-effective alternative to fossil fuels. UGA studies include crop genetics, the molecular structure of biomass, and identifying and developing microbes for converting biomass into biofuels.

Organs from Cells

A team of scientists including UGA researchers have grown a fully functional organ from scratch in a livinganimalforthefirsttime.Theadvancecouldonedayaidinthedevelopmentof laboratory-grownreplacementorgans.Theresearcherscreatedathymus,abutterfly-shapedglandandvitalcomponentof the human immune system. Located beneath the breastbone in the upper chest, the thymus is responsible forproducingT-lymphocytes,orT-cells,whichhelporganizeandleadthebody’sfightingforcesagainstthreats like bacteria, viruses, and even cancerous cells.

Vaccines for Elusive Diseases

Researchers at the University of Georgia have discovered that a virus commonly found in dogs may serve asthefoundationforthenextgreatbreakthroughinhumanvaccinedevelopment.Althoughharmlessinhumans,parainfluenzavirus5,orPIV5,isthoughttocontributetoupperrespiratoryinfectionsindogs, and it is a common target for canine vaccines designed to prevent kennel cough. This discovery is the basis for a platform virus that could be used in humans to protect against diseases that have eluded vaccine effortsfordecades,includingmumps,influenza,rabies,HIV,tuberculosis,andmalaria.

Food, Feed, Fiber and Fuel

UGA’s Plant Genome Mapping Laboratory is leading an international team to enhance sorghum production, funded by a $4.98 million grant from U.S. Agency for International Development, as part of the Feed the Future initiative. Grants totaling more than $2 million from the U.S. Departments of Agriculture and Energy have funded researchers in genetics and forestry to conduct fundamental research to better understand the plants that may one day produce the fuel that powers our vehicles and homes.

Agronomic Crops 40%

Pharma/Biotech 32%

Turfgrass/Ornamentals 16%

Horticultural Food Crops 7%

Engineering/Other 5%

Page 4: UGA Research 2014

The University of Georgia is committed to principles of equal opportunity and affirmative action.

Paul D. Coverdell Center for Biomedical & Health Sciences | 500 D.W. Brooks Dr. | Athens, Georgia 30602

research.uga.edu | [email protected] | 706.542.5969

On the Cover: Sugar Sleuths ResearchersattheComplexCarbohydrateResearchCenteraredelvingdeepintothefledglingfieldof glycoscience,whichexploresthestructures and functions of sugar molecules in plants, animals, and humans. Using the CCRC’s vast array of analytical tools, teams of scientists are unlocking the potential of these intricate sugar structures to develop new vaccines, make biofuels a cost-effective alternative to fossil fuels, and create powerful new vaccines, antibiotics, and other therapies for cancer, infectious diseases, and chronic diseases.

Photo: Crystallized glucose, Stefan Eberhard, CCRC

Restasis®

A prescription drug developed at UGA for treating chronic dry-eye disease is marketed in more than 35 countries, earning more than $70 million for University of Georgia research.

Chickens as BioreactorsA UGA researcher produced a portfolio of inventions to genetically engineer chickens as “bioreactors”fortheefficientproductionof proteins. A company based on these technologies, now called Synageva, focuses on new therapeutics for very rare human diseases.

PeanutsGeorgia 06G is among 19 elite peanut cultivars developed at UGA that account for over 90 percent of southeast U.S. market share helping Georgia lead the nation in peanut production.

BlueberriesFourteen patented UGA blueberry cultivars helped Georgia become the No. 1 state in blueberry production, surpassing peaches as the state’s leading fruit crop. UGA blueberry cultivars aregrownonallcontinentsexceptAntarctica.

ClevudineAn antiviral drug developed by College of Pharmacy researchers for the treatment of chronic hepatitis B is commercially sold in South Korea and the Philippines. The viral disease, which affects an estimated 240 million people around the world, can lead to liver cancer.

Poultry VaccinesHatchPak Cocci and Poulvac® Bron GA 08, developed in partnership with Merial and Zoetis, respectively, are recent additions to an arsenal of vaccines developed by UGA’s poultry research program to help protect Georgia’s $28 billion poultry industry.

TurfgrassThe TeamUGA turfgrass breeding program continues to develop superior turfgrass cultivars, including TifGrand Bermudgrass used on three stadiums in the 2014 World Cup.

ENStem-A™

A neural cell line developed by UGA researchers provides a unique research platform to help understand neurological disorders and aid in the discovery of new drugs to treat diseases such as Parkinson’s and Alzheimer’s.

UGA Research: From idea to marketplace More than 525 products originating from UGA research have reached the market through partnerships with industry over the last 35 years. In 2014 alone, industry partners brought 28 new products to market, including a bio-fermentation process to produce commodity chemicals, a new poultry vaccine, several new plant varieties, and educational tools.