University of California irvine sChool of MediCine

poster presentations & lab demonstrationfeatUring Phd and Ms stUdent researCh

sePteMber 28, 20174:00 PM - 5:00 PM

gillesPie hall foyer

Marlene CervantesBiological Chemistry

Advisor: Paolo Sassone-Corsi

Sarah CrossAnatomy and Neurobiology

Advisor: Frances Leslie

Megan CurranAnatomy and Neurobiology

Advisor: Tallie Z. Baram

BMAL1 Interacts with Nucleolar Protein NOP58 to Regulate the Maturation of

Pre-Ribosomal RNA

Modulation Of Kappa Opioid Receptor Activity by Nicotine

and Ethanol in Adolescent and Adult Male Rats

Translating a Novel MRI Signal that Predicts

Epileptogenesis to the Clinic: Signal Time-Course and

Evolution

Avital FischerEpidemiology

Advisor: Hoda Anton-Culver

Gianna FoteBiological Chemistry

Advisor: Kyoko Yokomori

Perception Matters: Stressful Life Events Increase Breast

Cancer Risk

Delineating the Role of MITF Isoforms in Melanogenesis

Analysis of the Interaction of Huntingtin (HTT) with Ubiquitin and APOE to

help Define its Role as an Autophagic Scaffold

Thomas GrossAnatomy and NeurobiologyAdvisor: Massimo Fiandaca

and Mark Mapstone

Amber HabowskiMicrobiology and Molecular Genetics

Advisor: Marian Waterman

Nabila HaqueMicrobiology and Molecular Genetics

Advisor: Yongsheng Shi

Metabolomic Biomarkers of Neurological Disease:

Specific Pitfalls and Emerging Promise

Wnt Signaling Regulation of Splicing in Differentiation

and Disease

A Novel Role for CPSF100 in the 3’ Processing of Enhancer

RNAs

Jessica FlesherBiological Chemistry

Advisor: Anand Ganesan

UCI SCHOOL OF MEDICINE PRESENTERS

2017 UCI School of Medicine Grad Day

David HermanEnvironmental Health Sciences

Advisor: Michael Kleinman

Autumn HolmesMicrobiology and Molecular Genetics

Advisor: Bert Semler

William HuMicrobiology and Molecular Genetics

Advisor: Rozanne Sandri-Goldin

How Does Co-Exposing ApoE-/- Mice with Various Forms

of Concentrated Ambient PM2.5 and Ozone Affect

Normal Electrocardiogram Measurements?

Modulation of a Multi-Functional Host Cell

Protein During Picornavirus Infections

The Structure of the Folded Domain From the Signature Multifunctional

Protein ICP27 From Herpes Simplex Virus-1 Reveals an

Intertwined Dimer

Rebecca JohnsonEnvironmental Health Science

Advisor: Michael Kleinman

Hugo You-Hsien LinPhysiology and Biophysics

Advisor: Ping H. Wang

Naomi LomeliExperimental Pathology

Advisor: Daniela Bota

Changes in Heart Rate Variability in ApoE-/- Mice

After Exposure to Particulate Matter and Semi-Volatile

Organic Compounds in Ambient Air Pollution

Mitochondrial AKT1 Signaling in Ischemia-

Reperfusion Injury in Kidney

N-Acetylcysteine (NAC) Treatment Can Reverse

Cisplatin-Induced Cognitive Damage in Rats

Christie MortalesMicrobiology and Molecular Genetics

Advisor: Michael Demitriou

Maliheh MovassatMicrobiology and Molecular Genetics

Advisor: Klemens Hertel

Karissa Jade Muñoz Physiology and BiophysicsAdvisor: Armando Villalta

N-Glycan Branching Inhibits Pro-Inflammatory B-Cell

Activity by Controlling TLR4 and BCR Signaling

Coupling Between Alternative Polyadenylation

and Alternative Splicing is Limited to Terminal Introns

A Potential Role For Tregs in Suppressing Muscle

Inflammation and Promoting Regeneration

UCI SCHOOL OF MEDICINE PRESENTERS

2017 UCI School of Medicine Grad Day

Shantell NolenEpidemiology

Advisor: Hoda Anton-Culver and Daniela Bota

Andrea M. Reyes-OrtizBiological Chemistry

Advisor: Leslie M. Thompson

Sarah RoyerAnatomy and NeurobiologyAdvisor: Aileen Anderson

The Effects of Sequential Treatments on Hippocampal Volume in Malignant Glioma

Patients

Blood-Brain Barrier and Neurovascular Unit Deficits

in Huntington’s Disease Induced Pluripotent Stem

Cell-Derived Cells

A Novel Role for C1q as an Inhibitory Cue for

Neurogenesis During Aging

Lily WidyastutiBiological Chemistry

Advisor: Mika Zaragoza

Jesse HoltPhysiology and Biophysics

Advisor: Medha Pathak

Nicole ChmielewskiEnvironmental Health Sciences

Advisor: Charles Limoli

Induced Pluripotent Stem Cell Disease Modeling of LMNA-Associated

Cardiomyopathy Reveals Perturbed Embryoid Body

Formation

Piezo1 Transduces Extracellular Matrix Mechanical Cues to

Direct Neural Stem Cell Differentiation

Characterizing the Time Course of Radiation-Induced Memory Impairments and Network Activity in Rats

Ken HayamaMicrobiology and Molecular Genetics

Advisor: Michael Demetriou

Abhinav GroverBiomedical and Translational Science

Advisor: Raymond Wang

Andrew R YaleAnatomy and Neurobiology

Advisor: Lisa Flanagan

Impaired T Cell Immunity in the Elderly Via N-Glycosylation

Engineering Pompe Disease Models Using CRISPR-Cas9

Genome Editing

The N-Glycan Branching Pathway Alters Neural Stem Cell Biophysical Properties and Shifts Fate Potential

Towards Astrogenesis

UCI SCHOOL OF MEDICINE PRESENTERS

2017 UCI School of Medicine Grad Day

The UCI School of Medicine wishes to thank the Student Advisory Council for their contributions to Grad Day.

We also recognize the following institutions for their support:

UCI SCHOOL OF MEDICINE PRESENTERS

Ron LeavittRadiation Oncology

Advisor: Charles Limoli

Characterizing the Functional Cargo of

Human Stem-Cell Derived Microvesicles that Mitigate

the Effects of Cranial Irradiation

George ChenMicrobiology and Molecular Genetics

Advisor: Marian Waterman

Linking Wnt Signaling to Emergent Patterns

of Metabolism in Colon Cancer

Jenna KastenschmidtPhysiology and BiophysicsAdvisor: Armando Villalta

A Potential Role for Group 2 Innate Lymphoid Cells in

Muscular Dystrophy

2017 UCI School of Medicine Grad Day

Albert TaPhysiology and Biophysics

Advisor: Ping Wang

Investigating the Protective Effects of Mitochondrial Akt1 Signaling against

Diabetic Cardiomyopathy