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How dys expression is regulated?
•Is dys auto-regulated by Dys:Tgo?
N283-GFP,dys/Tm3, twi-gal4, UAS-GFPC1.7-GFP, dys/TM3, twi-gal4, UAS-GFP
•Is dys regulated by esg?esg/cyo, twi-gal4, UAS-GFP; N283esg/cyo, twi-gal4, UAS-GFP; C1.7
•Identify other transcription factors binding sites in dys enhancer.
Identify dys fusion cells enhancer in C1.7 and G1.7
Ongoing……
Summary of dys Function
N
TC GTG
members only (Protein trafficking)
Trachealess (Migration)
CG13196, E-cadherin (cell adhesion)
CG15252 (unknown function)
TgoDys
TgoDys
TgoDys
Identified dys Targets