Tissue Chapter 4 Link. Tissues Tissue: 4 Primary Tissue Types 1.Epithelial 2.Connective 3.Muscle 4.Nervous

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Tissue Chapter 4 Link Slide 2 Tissues Tissue: 4 Primary Tissue Types 1.Epithelial 2.Connective 3.Muscle 4.Nervous http://www.stegen.k12.mo.us/tchrpges/sghs/ksulkowski/images/2 0_Simple_Columnar_Epithelial_Tissue.jpg Slide 3 Match Tissue Type to Function 1.Epithelial 2.Connective 3.Nervous 4.Muscle A.Supports, protects, binds other tissues together B.Internal communication C.Contracts to cause movement D.Forms boundaries between different environments, protects, secretes, absorbs, filters Slide 4 Epithelial Tissue (Epithelium) Two main types (by location): 1.Covering and lining epithelium 2.Glandular epithelium http://www.bio.davidson.edu/people/kabernd/BerndCV/Lab/EpithelialInfoWeb/g oblet%20cells%20.jpg Forms boundaries b/w different environments Slide 5 Functions of Epithelial Tissue Protection Absorption Filtration Excretion Secretion Sensory reception Slide 6 Characteristics of Epithelial Tissue 1.Cells have polarity 2.Are composed of closely packed cells 3.Supported by a connective tissue reticular lamina (under the basal lamina) 4.Avascular but innervated 5.High rate of regeneration Slide 7 Classification of Epithelia Ask two questions: 1.How many layers? 1 = simple epithelium >1 = stratified epithelium Slide 8 Classification of Epithelia 2.What type of cell? Squamous Cuboidal Columnar Note: if stratified, name according to apical layer of cells! Slide 9 Overview of Epithelial Tissues For each of the following types of epithelia, note: Description Function Location Slide 10 Simple Epithelia Single cell layer (usually very thin) Concerned with: Absorption Secretion Filtration NOT concerned with: protection Simple squamous, simple cuboidal, simple columnar, pseudo stratified columnar Slide 11 Simple Squamous Epithelium Description Function Location Photomicrograph: Simple squamous epithelium forming part of the alveolar (air sac) walls (125x). Note: ENDOTHELIUM AND MESOTHELIUM Slide 12 Description Function Location (b) Simple cuboidal epithelium Photomicrograph: Simple cuboidal epithelium in kidney tubules (430x). Simple Cuboidal Epithelium Slide 13 (c) Simple columnar epithelium Photomicrograph: Simple columnar epithelium of the stomach mucosa (860X). Simple Columnar Epithelium Description Function Location Slide 14 (c) Simple columnar epithelium Pseudostratified Columnar Epithelium Description Function Location Photomicrograph: Pseudostratified ciliated columnar epithelium lining the human trachea (570x). Slide 15 Stratified Epithelium 2+ cell layers Regenerate from below More durable than simple epithelia Major role: Protection Slide 16 Stratified Squamous Epithelium Description Function Location Photomicrograph: Stratified squamous epithelium lining the esophagus (285x). Slide 17 Stratified Cuboidal Epithelium Description Function Location Slide 18 Stratified Columnar Epithelium http://www.sciencephoto.com/image/115414/large/C0051252- Stratified_columnar_epithelium,_urethra-SPL.jpg Description Function Location Slide 19 Transitional Epithelium Description Function Location Photomicrograph: Transitional epithelium lining the urinary bladder, relaxed state (360X); note the bulbous, or rounded, appearance of the cells at the surface; these cells flatten and become elongated when the bladder is filled with urine. Slide 20 Glandular Epithelia Gland: one or more cells that secretes and aqueous fluid Classified by: Site of product release Endocrine Exocrine Relative number of cells forming the gland Unicellular Multicellular Slide 21 Glands Endocrine Ductless glands Secrete hormones that travel through lymph or blood to target organs Examples: Thyroid Gland, Pituitary Gland Covered in Ch. 16 Exocrine Secrete products into ducts Secretions released onto body surfaces (skin) or into body cavities Examples: mucous, sweat, oil, and salivary glands More numerous! Slide 22 Unicellular Exocrine Glands Goblet cell and Mucous cell Mucin -> mucous Slide 23 Multicellular Exocrine Glands Composed of a duct and a secretory unit Classified according to: 1.Duct type Simple Compound 2.Structure of secretory units tubular alveolar tubuloalveolar Slide 24 Figure 4.5 Compound duct structure (duct branches) Simple tubular Example Intestinal glands Simple branched tubular Example Stomach (gastric) glands Compound tubular Example Duodenal glands of small intestine Compound alveolar Example Mammary glands Simple alveolar Example No important example in humans Simple branched alveolar Example Sebaceous (oil) glands Compound tubuloalveolar Example Salivary glands Tubular secretory structure Alveolar secretory structure Surface epitheliumDuctSecretory epithelium Simple duct structure (duct does not branch) Slide 25 Modes of Secretion Merocrine Products are secreted by exocytosis pancreas, sweat and salivary glands Holocrine Products are secreted by rupture of gland cells sebaceous (oil) glands Slide 26 Connective Tissue Most abundant and widely distributed tissue type Four main classes 1)Connective Tissue Proper 2)Cartilage 3)Bone Tissue 4)Blood See Table 4.1 Slide 27 Major Functions of Connective Tissue 1)Binding and Support 2)Protection 3)Insulation 4)Stores reserve fuel 5)Transports Slide 28 Characteristics of Connective Tissue Connective tissues have: Mesenchyme as their common tissue of origin Varying degrees of vascularity Cells separated by nonliving extracellular matrix (ground substance and fibers) 3 Structural Elements Ground substance Fibers Cells Slide 29 Structural Elements of Connective Tissue Ground substance Medium through which solutes diffuse between blood capillaries and cells Components: Interstitial fluid Adhesion proteins ( glue ) Proteoglycans Protein core + large polysaccharides Trap water -> viscosity Slide 30 Structural Elements of Connective Tissue Connective Tissue Fibers Collagen (white fibers) Strongest and most abundant type Provides high tensile strength Elastic (yellow fibers) Networks of long, thin, elastin fibers that allow for stretch/recoil Reticular Short, fine, highly branched collagenous fibers Slide 31 Structural Elements of Connective Tissue Cells (see table 4.1) Mitotically active and secretory cells = blasts Fibroblasts, chondroblasts, osteoblasts, hematopoietic stem cells Mature cells = cytes Chondrocytes, osteocytes Other cell types Fat cells, white blood cells, mast cells, and macrophages Slide 32 Figure 4.7 Macrophage Fibroblast Lymphocyte Fat cell Mast cell Neutrophil Capillary Cell types Extracellular matrix Fibers Collagen fiber Elastic fiber Reticular fiber Ground substance Slide 33 Connective Tissue: Embryonic Mesenchymeembryonic connective tissue Gives rise to all other connective tissues Gel-like ground substance with fibers and star- shaped mesenchymal cells Slide 34 Connective Tissue Proper Types: Loose connective tissue Areolar Adipose Reticular Dense connective tissue Dense regular Dense irregular Elastic Slide 35 Loose Connective: Areolar Description Function Location Photomicrograph: Areolar connective tissue, a soft packaging tissue of the body (300x). CONNECTIVE TISSUE PROPER Slide 36 Loose Connective: Adipose Description Function Location Photomicrograph: Adipose tissue from the subcutaneous layer under the skin (350x). CONNECTIVE TISSUE PROPER Slide 37 Loose Connective: Reticular Description Function Location Photomicrograph: Dark-staining network of reticular connective tissue fibers forming the internal skeleton of the spleen (350x). CONNECTIVE TISSUE PROPER Slide 38 Dense Connective: Dense Regular Description Function Location Photomicrograph: Dense regular connective tissue from a tendon (500x). CONNECTIVE TISSUE PROPER Slide 39 Dense Connective: Dense Irregular Description Function Location Photomicrograph: Dense irregular connective tissue from the dermis of the skin (400x). CONNECTIVE TISSUE PROPER Slide 40 Dense Connective: Elastic Description Function Location Photomicrograph: Elastic connective tissue in the wall of the aorta (250x). CONNECTIVE TISSUE PROPER Slide 41 Connective Tissue: Cartilage Stands up to both compression and tension No nerve fibers, avascular 80% water Chondroblasts produce new matrix Chondrocytes mature cartilage cells Found in small groups in lacunae Slide 42 Hyaline Cartilage Description Function Location Photomicrograph: Hyaline cartilage from the trachea (750x). CARTILAGE Slide 43 Elastic Cartilage Description Function Location Photomicrograph: Elastic cartilage from the human ear pinna; forms the flexible skeleton of the ear (800x). CARTILAGE Slide 44 Fibrocartilage Description Function Location Photomicrograph: Fibrocartilage of an intervertebral disc (125x). Special staining produced the blue color seen. CARTILAGE Slide 45 Connective Tissue: Bone Description Function Location Photomicrograph: Cross- sectional view of bone (125x). Slide 46 Connective Tissue: Blood Description Function Location Photomicrograph: Smear of human blood (1860x); two white blood cells (neutrophil in upper left and lymphocyte in lower right) are seen surrounded by red blood cells. Slide 47 Nervous Tissue Description Function Location Photomicrograph: Neurons (350x) Slide 48 Muscle Tissue Highly cellular, well vascularized Movement Types 1.Skeletal 2.Cardiac 3.Smooth Slide 49 Skeletal Muscle Description Function Location Photomicrograph: Skeletal muscle (approx. 460x). Notice the obvious banding pattern and the fact that these large cells are multinucleate. MUSCLE TISSUE Slide 50 Cardiac Muscle Description Function Location Photomicrograph: Cardiac muscle (500X); notice the striations, branching of cells, and the intercalated discs. MUSCLE TISSUE Slide 51 Smooth Muscle Description Function Location Photomicrograph: Sheet of smooth muscle (200x). MUSCLE TISSUE Slide 52 Epithelial Membranes Cutaneous membrane (skin) Mucous membranes Mucosae Line body cavities open to the exterior (e.g., digestive and respiratory tracts) Serous Membranes Serosaemembranes (mesothelium + areolar tissue) in a closed ventral body cavity Parietal serosae line internal body walls Visceral serosae cover internal organs Slide 53 Figure 4.11b Mucosa of nasal cavity Mucosa of lung bronchi Mucosa of mouth Esophagus lining (b) Mucous membranes line body cavities open to the exterior. Slide 54 Figure 4.11c Parietal pericardium Visceral pericardium (c) Serous membranes line body cavities closed to the exterior. Parietal peritoneum Visceral peritoneum Parietal pleura Visceral pleura Slide 55 Steps in Tissue Repair Inflammation Organization and Restored Blood Supply Regeneration and Fibrosis Slide 56 Figure 4.12, step 1 Scab Blood clot in incised wound Epidermis Vein Inflammatory chemicals Inflammation sets the stage: Severed blood vessels bleed and inflammatory chemicals are released. Local blood vessels become more permeable, allowing white blood cells, fluid, clotting proteins and other plasma proteins to seep into the injured area. Clotting occurs; surface dries and forms a scab. Migrating white blood cell Artery 1 Slide 57 Figure 4.12, step 2 Regenerating epithelium Area of granulation tissue ingrowth Fibroblast Macrophage Organization restores the blood supply: The clot is replaced by granulation tissue, which restores the vascular supply. Fibroblasts produce collagen fibers that bridge the gap. Macrophages phagocytize cell debris. Surface epithelial cells multiply and migrate over the granulation tissue. 2 Slide 58 Figure 4.12, step 3 Regenerated epithelium Fibrosed area Regeneration and fibrosis effect permanent repair: The fibrosed area matures and contracts; the epithelium thickens. A fully regenerated epithelium with an underlying area of scar tissue results. 3 Slide 59 Developmental Aspects Primary germ layers: ectoderm, mesoderm, and endoderm Formed early in embryonic development Specialize to form the four primary tissues Nerve tissue arises from ectoderm Muscle and connective tissues arise from mesoderm Epithelial tissues arise from all three germ layers