HOTEL INFORMATIONWe are pleased to provide the following information on hotels in the vicinity of Memorial Sloan Kettering Cancer Center:Affinia Gardens Hotel215 East 64th Street (between 2nd and 3rd Avenue)(212) 355-1230 (within US)(800) 637-8483 (reservations)www.affinia.comMarriott Courtyard Midtown East866 Third Avenue (between 52nd and 53rd Street)(212)-644-1300 (within US)(800)-637-8483 (reservations)www.marriot.comAdditional hotel options can also be found at the following link: http://www.mskcc.org/accommodationsInformation regarding group hotel rates and optional cultural activities will be distributed to course registrants.

Educational ObjectivesParticipants will learn the current classifications and diagnostic criteria for tumors and tumor-like lesions of the selected subspecialty areas, including both common and unusual entities. The appropriate use of ancillary diagnostic techniques will be highlighted. Complete differential diagnoses will be discussed, and a practical, problem-oriented approach to the pathologic evaluation of specimens will be emphasized. Participants will learn about the clinical features of the various tumor entities along with pathologic and molecular prognostic factors and predictors of therapeutic responsiveness.

Goals of the CourseThe purpose of this course is to review in depth selected topics in the pathology of neoplastic diseases, with an emphasis on clinical features, diagnostic criteria including the use of novel diagnostic modalities when applicable, prognostic factors, and assessment of therapy-related factors.

Course DesignThis course consists of didactic lectures with question and discussion periods as well as case presentations and interactive slide seminars. The lectures are organized along the lines of the specific subspecialties to be covered this year, with 1-2 days devoted to each of three areas (Genitourinary Pathology, Gastrointestinal Pathology, and Thoracic Pathology).

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Frozen Section (Tues. 5/5)

$_________

Thoracic pathology (Wed. 5/6)

$_________

Genitourinary pathology (Thurs. 5/7)

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Registration NotesA reduced rate of $750 ($650 before 3/15/15) is offered to pathologists-in-training; the registration must be accompanied by a letter from the residency or fellowship program director certifying the applicant's status. Optional slide seminars are offered for an additional fee of $50 each. Seating is limited.

Registration fees include attendance at the course, handout materials, and meals. Written notice of cancellation must be received no later than April 1, 2015. Refunds are subject to a $65 administrative charge and will be processed after the conference. For more information, please contact the CME office at 646-227-2025, Fax: 212-557-0773, Address: 633 Third Avenue, 12th FL, New York, NY 10017 or via e-mail brodheap@mskcc.org.

Please visit: www.mskcc.org/surgicalpathologycourse to register or for more information.

The Pathology ofNeoplasticDiseases

Brochure_Surgical_Path_2015_final.indd 1Brochure_Surgical_Path_2015_final.indd 1 2/9/2015 9:57:39 AM2/9/2015 9:57:39 AM

Monday, May 4, 2015

8:00-8:10 Opening remarks David S. Klimstra, M.D.

8:10-8:55 Diagnosis of ductal carcinoma of the pancreasDavid S. Klimstra, M.D.

8:55-9:40 Cystic Neoplasms of the PancreasOlca Basturk, M.D.

9:40-10:10 Break

10:10-10:55 Pancreatic cytopathologyCarlie Sigel, M.D.

10:55-11:40 Gastroesophageal Carcinomas and Their Precursor Lesions - The Barrett’s Anxiety Laura Tang, M.D., Ph.D.

11:40-12:10 HER2 testing in gastric and gastroesophageal adenocarcinomasEfsevia Vakiani, M.D., Ph.D.

12:10-1:30 Lunch

1:30-2:15 Serrated lesions of the large bowel Christine Iacobuzio-Donahue, M.D., Ph.D.

2:15-3:00 An update on Lynch syndrome screening and other MSI-related issues Jinru Shia, M.D.

3:00-3:30 Break

3:30-4:15 Molecular for Millennials: A Case-Based Approach to GI Malignancies Jaclyn Hechtman, M.D

4:30-6:00 Slide Seminar: Gastrointestinal pathologyDavid S. Klimstra, M.D.

Tuesday, May 5, 2015

8:00-8:45 Neuroendocrine neoplasms: general concepts and pancreatic NETs David S. Klimstra, M.D.

8:45-9:30 Conundrums and Caveats in Neuroendocrine Neoplasms of the GI TractLaura H. Tang, M.D., Ph.D.

9:30-10:00 Break

10:00-10:45 Diagnostic approach to hepatocellular neoplasms Efsevia Vakiani, M.D., Ph.D.

10:45-11:30 Neoplasms of the Gallbladder and Biliary TractOlca Basturk, M.D.

11:30-12:15 Issues in TNM staging of CRC Jinru Shia, M.D.

12:15-1:30 Lunch

1:30-2:15 The new WHO Classification of Lung Cancer William D. Travis, M.D.

2:15-3:00 Molecular Aspects of Lung Cancer Maria E. Arcila, M.D.

3:00-3:30 Break

3:30-4:15 Immunohistochemistry in Lung Cancer Diagnosis and Predictive Marker Testing Natasha Rekhtman, M.D., Ph.D.

4:30-6:00 Slide Seminar:Frozen SectionVictor E. Reuter, M.D.

Wednesday, May 6, 2015

10:30-11:15 The Role of Small Biopsies and Cytology in Lung Cancer Diagnosis Andre L. Moreira, M.D., Ph.D.

11:15-11:45 Lung Neuroendocrine Tumors Natasha Rekhtman, M.D., Ph.D.

11:45-12:15 Unusual Lung Tumors William D. Travis, M.D.

12:15-1:30 Lunch

1:30-2:15 Mediastinal Tumors Andre L. Moreira, M.D., Ph.D.

2:15-3:00 Pleural Malignant MesotheliomaLucian Chirieac, M.D.

3:00-3:30 Break

3:30-4:15 Sarcomatous and Soft Tissue Pleural Tumors Lucian Chirieac, M.D.

4:30-6:00 Slide Seminar:Thoracic pathologyAndre L. Moreira, M.D., Ph.D., Natasha Rekhtman, M.D., Ph.D., William D. Travis, M.D.

Thursday, May 7, 2015

8:00-8:45 New insights into the classification of neoplasms of the kidneyYingbei Chen, M.D., Ph.D.

8:45-9:30 The use of immunohistochemistry and other ancillary studies in the diagnosis of tumors of the kidney and testisHikmat Al-Ahmadie, M.D.

9:30-10:00 Break

10:00-10:45 Classification of tumors of the urothelial tract in the age of personalized medicineHikmat Al-Ahmadie, M.D.

10:45-11:30 Benign mimics of urothelial neoplasiaVictor E. Reuter, M.D.

11:30-12:15 New insights into the classification of neoplasms of the testisSatish K. Tickoo, M.D.

12:15-1:30 Lunch

1:30-2:15 Intraoperative consultations in genitourinary pathologyAnuradha Gopalan, M.B.B.S.

2:15-3:00 The use of immunohistochemistry and other ancillary studies in the diagnosis of tumors of the bladder and prostateYingbei Chen, M.D., Ph.D.

3:00-3:30 Break

3:30-4:15 The evolution of Gleason grade; where are we now and where are we headed?Peter Humphrey, M.D., Ph.D.

4:30-6:00 Slide Seminar: Genitourinary pathologyPeter A. Humphrey, M.D., Ph.D.

Friday, May 8, 2015

8:00-8:45 Prostate pathology: mimics, precursors and high risk lesionsSamson Fine , M.D.

8:45-9:45 Interactive slide session: challenging GU cases that should wake you up this morningSamson Fine, M.D.

9:45-10 15 Break

10:15-10:45 Pathologic evaluation of prostate needle biopsies in the era of active surveillanceAnuradha Gopalan, M.B.B.S.

10:45-11:30 Pathology informatics and digital pathology; enhancing the quality of careS. Joseph Sirintrapun, M.D.

11:30-12:00 Pathologic evaluation of renal tumors with oncocytic featuresSatish K. Tickoo, M.D.

12:00-12:30 Evaluation of the surface urothelium in the absence of invasive disease; flat urothelial lesions with atypiaVictor E. Reuter, M.D.

Course Faculty

Summary:This four and one half day course will provide an up-to-date review of the pathology of selected subspecialty areas of neoplastic disease, including Genitourinary, Gastrointestinal and Thoracic pathology. Appropriate use of advanced diagnostic techniques such as immunohistochemistry and molecular pathology will be incorporated into the lectures, including the assessment of therapeutic biomarkers. Case presentations will also be integrated into some sessions. Finally, there will be optional more intimate, interactive slide seminar sessions on selected topics in Genitourinary, Gastrointestinal and Thoracic pathology (registration is limited, additional fees apply). The Department of Pathology at Memorial Sloan Kettering Cancer Center has produced a course on the Surgical Pathology of Neoplastic Diseases for over 30 years. With the 33rd edition, we continue to expand the scope of the course to reflect the increasing contributions of cytopathology, immunopathology, and molecular pathology. The course faculty will include the attending pathology staff from Memorial Sloan Kettering Cancer Center along with selected visiting lecturers. Course participants will receive a complete syllabus with references, along with digitized glass slides of cases for review. The course will be held on the campus of Memorial Sloan Kettering Cancer Center on the Upper East Side of Manhattan, a vibrant and safe neighborhood within easy access of the widely varied cultural attractions of New York City. A full breakfast and lunch will be provided daily.

Audience:This course is directed toward practicing pathologists, both in academic and private practice situations, as well as residents and fellows in pathology, who wish to broaden their understanding of neoplastic diseases.

Accreditation StatementMemorial Sloan Kettering Cancer Center is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

CME CreditMemorial Sloan Kettering Cancer Center designates this educational activity for a maximum of 27.25 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity. An additional 4 credits is available for participation in optional slide seminars. Self assessment module (SAM) questions will be prepared to enable participants to earn up to 20 SAM credits.

Location:Memorial Sloan Kettering Cancer CenterRockefeller Research Laboratories Auditorium 430 East 67th Street Between First and York Avenues New York, NY 10065

Phone:646-227-2025Fax:212-557-0773E-mail:brodheap@mskcc.org

COURSE DIRECTORS

David S. Klimstra, M.D.Chairman, Pathology DepartmentAttending Pathologist

Meera R. Hameed, M.B.B.S.Acting Chief, Surgical Pathology ServiceAttending Pathologist

COURSE SECRETARY

Sarah Cook

MSKCC COURSE FACULTY

Hikmat Al-Ahmadie, M.D.Assistant Attending Pathologist

Maria E. Arcila, M.D.Assistant Attending Pathologist

Olca Basturk, M.D.Assistant Attending Pathologist

Yingbei Chen, M.D., Ph.D.Assistant Attending Pathologist

Samson W. Fine, M.D.Assistant Attending Pathologist

Anuradha Gopalan, M.B.B.S.Assistant Attending Pathologist

Jaclyn Hechtman, M.D.Assistant Attending Pathologist

Christine Iacobuzio-Donahue, M.D., Ph.DAttending PathologistAssociate Director, Rubenstein Center for Pancreatic Cancer Research

David S. Klimstra, M.D.Chairman, Pathology DepartmentAttending Pathologist

Andre L. Moreira, M.D., Ph.D.Associate Attending Pathologist

Natasha Rekhtman, M.D., Ph.D.Assistant Attending Pathologist

Victor E. Reuter, M.D.Vice Chairman, Pathology DepartmentAttending PathologistDirector of Genitourinary Pathology Team

Jinru Shia, M.D.Attending PathologistDirector of GI Pathology Team

ASSOCIATE COURSE DIRECTORS

Victor E. Reuter, M.D.Vice Chairman, Pathology DepartmentAttending PathologistDirector of Genitourinary Pathology Team

Jinru Shia, M.D.Attending PathologistDirector of GI Pathology Team

William D. Travis, M.D.Attending PathologistDirector of Thorcic Pathology Team

Carlie Sigel, M.D.Assistant Attending Pathologist

S. Joseph Sirintrapun, M.D.Assistant Attending Pathologist

Laura H. Tang, M.D., Ph.D.Associate Attending Pathologist

Satish Tickoo, M.D.Attending Pathologist

William D. Travis, M.D.Attending PathologistDirector of Thorcic Pathology Team

Efsevia Vakiani, M.D., Ph.D.Assistant Attending Pathologist

GUEST FACULTY

Lucian Chirieac, M.D.Department of PathologyBrigham and Women’s HospitalBoston, MA

Peter A Humphrey MD, PhDDirector, Genitourinary PathologyDepartment of PathologyYale School of MedicineNew Haven, CT

All sessions will be held in the Auditorium of the Rockefeller Research Laboratories, located at 430 East 67th Street between York and First Avenues on the Upper East Side of Manhattan.THE PATHOLOGY OF NEOPLASTIC DISEASES COURSE SCHEDULE May 4 - May 8, 2015

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