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The iGEM Jamboree at MIT
iGEM 20045 teams
iGEM 200513 teams
Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley Davidson Harvard UCSF
Princeton Oklahoma ETH Zurich MIT Caltech Toronto Cambridge Texas Penn State Berkeley Davidson Harvard UCSF
iGEM 200513 teams
iGEM 200632 teams
Putting the “i” in iGEM
200754 teams
200884 teams
2009112 teams
Chemistry
Mathematics Computer Science
How is synthetic biology well-suited for interdisciplinary research?
Environment Energy Medicine Technology
Creativity Flexibility
If you have a common interest, you can find a synthetic biology way to approach it!
Adaptability
Synthetic Biology Project Exampleshttp://2010.igem.org/Main_Page
highGEM
Greenfield Central High School, Greenfield, INRebecca Schinii [email protected]
Ethics/ Human Practice
Construct Version
Synthetic biology uses molecular methods to construct DNA-based devices to perform novel functions. Synthetic biologists design, model, and construct biological parts, devices and systems by engineering and modifying existing biological systems. For instance, synthetic biologists can produce microbes that make useful chemicals. Synthetic biology gives scientists the tools to build biological devices from smaller biological units in much the same way as an engineer constructs a building from smaller construction materials. Synthetic biology has the potential to develop technologies that could lead the way in the 21st century.
Create Version
Synthetic biology uses molecular methods to create modified living organisms that have never existed before. These DNA-based devices perform new functions not found in nature. Synthetic biologists redesign and modify existing, natural biological systems. For instance, synthetic biologists can create new versions of microbes that make chemicals not naturally found in microbes. In many ways, synthetic biology allows scientists to redesign biological processes and create organisms not found in nature. Synthetic biology has the potential to develop technologies that could lead the way in the 21st century.
Ethics and Word Choice
Ethics and Word Choice
Energy
2008 Project by Harvard iGEM Team
http://2008.igem.org/Team:Harvard
Shewanella oneidensis MR-1
Four 2009 iGEM Projects
http://2009.igem.org/Team:HKU-HKBU
http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller
http://2009.igem.org/Team:HKU-HKBU/Assembly#Step_6._Using_the_Speed_Controller
Environment
Edinburgh iGEM 2006
Awards: Best Real World Application, Best Poster
Poison Water
• Arsenic poisoning affects 100 million people
• Serious in Bangladesh
• Wells tap sedimentary layer with Arsenic• 1 in 4 wells contaminated
• Testing methods expensive, require instruments and expertise
Range of Outputs
If no arsenic is present: Urease raises the pH to 9-10
If 5 ppb arsenic is present: Repressor shuts down Urease, pH remains neutral, pH 7
If 20 ppb arsenic is present: LacZ produced, pH 4.5
Technology
http://parts.mit.edu/igem07/index.php/Peking
Toggle Switch
Toggle Switch
A B Output
0 0 1
0 1 0
1 0 0
1 1 0
NOR Logic Gate
Toggle Switch
Explore the 2010 iGEM Wiki
Google search iGEM 2010 (first hit)
http://2010.igem.org/Main_Page
Go explore!!