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POSTER PRESENTATION Open Access The early role of CMR in the assessment of cardiomyopathy Matthew Barrett 1,2* , Deirdre F Waterhouse 2,1 From 15th Annual SCMR Scientific Sessions Orlando, FL, USA. 2-5 February 2012 Summary We performed a one year study to assess the impact of CMR imaging on the management of patients with sus- pected or confirmed cardiomyopathy. Background Investigation and risk stratification of suspected or con- firmed cardiomyopathy traditionally involves correlation between electrocardiographic, echocardiographic and angiographic findings in an appropriate clinical setting. Cardiac Magnetic Resonance (CMR) is the new gold standard in assessment of cardiac structure, function and perfusion, provided in a single study. Aetiology and prognostic factors may be investigated concurrently. Methods This was a single centre, 12-month experience of patients referred for assessment of presumptive cardio- myopathy. Images were provided by a 1.5T GE Scanner and were reported by a Level 3 Reporter. Results 224 patients (145 male, 79 female) underwent CMR assessment of cardiomyopathy. 177 (79%) were outpati- ent referrals. The primary indications for CMR included 49 (21.9%) - Arrhythmia 42 (18.8%) - Abnormal echocardiogram with no cause found 35 (15.6%) - Cardiac symptoms with normal coronaries 32 (14.3%) - Screening for family history of CM/SCD 23 (10.3%) - Abnormal ECG/holter/stress test 18 (8%) - Follow-up of previously diagnosed CM 17 (7.6%) - Systemic illness 7 (3.1%) - ICD insertion CMR provided sufficient information to confirm or outrule cardiomyopathy in 68.2% of cases. A new diag- nosis of cardiomyopathy was made in 25.4%. CMR also had an important role in ongoing assessment of patients with established diagnosis of cardiomyopathy, with 22.2% having their previous diagnosis outruled and 27.8% being recommended for device implantation as a direct result of CMR findings. Overall in cardiomyopathy assessment, CMR had an impact on management in 50% of patients, with a thera- peutic consequence on 36.2%, including medication changes, angiography and device insertion. Conclusions Patients at all stages of the clinical spectrum of cardio- myopathy, from initial presentation to institution of therapy and long-term follow up may benefit from CMR. CMR should be implemented early in the diagnostis of suspected cardiomyopathy. Our data demonstrates the significant impact CMR consistently has on confirming diagnosis, guiding therapy and providing accurate prog- nosis in this patient group. Funding None. Author details 1 SVUH, Dublin, Ireland. 2 CMR Department, Blackrock Clinic, Dublin, Ireland. 1 SVUH, Dublin, Ireland Full list of author information is available at the end of the article Table 1 Baseline Characteristics Gender Male - 145 Female - 79 Referral Source OPD - 177 Inpatient - 47 BMI Mean - 26.7 kg/m2 StDev - 4.4 kg/m2 Age Mean - 63.4 years StDev - 16.7 years Barrett and Waterhouse Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):P146 http://www.jcmr-online.com/content/14/S1/P146 © 2012 Barrett and Waterhouse; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The early role of CMR in the assessment of cardiomyopathy

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POSTER PRESENTATION Open Access

The early role of CMR in the assessment ofcardiomyopathyMatthew Barrett1,2*, Deirdre F Waterhouse2,1

From 15th Annual SCMR Scientific SessionsOrlando, FL, USA. 2-5 February 2012

SummaryWe performed a one year study to assess the impact ofCMR imaging on the management of patients with sus-pected or confirmed cardiomyopathy.

BackgroundInvestigation and risk stratification of suspected or con-firmed cardiomyopathy traditionally involves correlationbetween electrocardiographic, echocardiographic andangiographic findings in an appropriate clinical setting.Cardiac Magnetic Resonance (CMR) is the new goldstandard in assessment of cardiac structure, functionand perfusion, provided in a single study. Aetiology andprognostic factors may be investigated concurrently.

MethodsThis was a single centre, 12-month experience ofpatients referred for assessment of presumptive cardio-myopathy. Images were provided by a 1.5T GE Scannerand were reported by a Level 3 Reporter.

Results224 patients (145 male, 79 female) underwent CMRassessment of cardiomyopathy. 177 (79%) were outpati-ent referrals.The primary indications for CMR included49 (21.9%) - Arrhythmia42 (18.8%) - Abnormal echocardiogram with no cause

found35 (15.6%) - Cardiac symptoms with normal

coronaries32 (14.3%) - Screening for family history of CM/SCD23 (10.3%) - Abnormal ECG/holter/stress test18 (8%) - Follow-up of previously diagnosed CM17 (7.6%) - Systemic illness

7 (3.1%) - ICD insertionCMR provided sufficient information to confirm or

outrule cardiomyopathy in 68.2% of cases. A new diag-nosis of cardiomyopathy was made in 25.4%. CMR alsohad an important role in ongoing assessment of patientswith established diagnosis of cardiomyopathy, with22.2% having their previous diagnosis outruled and27.8% being recommended for device implantation as adirect result of CMR findings.Overall in cardiomyopathy assessment, CMR had an

impact on management in 50% of patients, with a thera-peutic consequence on 36.2%, including medicationchanges, angiography and device insertion.

ConclusionsPatients at all stages of the clinical spectrum of cardio-myopathy, from initial presentation to institution oftherapy and long-term follow up may benefit fromCMR.CMR should be implemented early in the diagnostis of

suspected cardiomyopathy. Our data demonstrates thesignificant impact CMR consistently has on confirmingdiagnosis, guiding therapy and providing accurate prog-nosis in this patient group.

FundingNone.

Author details1SVUH, Dublin, Ireland. 2CMR Department, Blackrock Clinic, Dublin, Ireland.

1SVUH, Dublin, IrelandFull list of author information is available at the end of the article

Table 1 Baseline Characteristics

Gender Male - 145 Female - 79

Referral Source OPD - 177 Inpatient - 47

BMI Mean - 26.7 kg/m2 StDev - 4.4 kg/m2

Age Mean - 63.4 years StDev - 16.7 years

Barrett and Waterhouse Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):P146http://www.jcmr-online.com/content/14/S1/P146

© 2012 Barrett and Waterhouse; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the CreativeCommons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, andreproduction in any medium, provided the original work is properly cited.

Published: 1 February 2012

doi:10.1186/1532-429X-14-S1-P146Cite this article as: Barrett and Waterhouse: The early role of CMR in theassessment of cardiomyopathy. Journal of Cardiovascular MagneticResonance 2012 14(Suppl 1):P146.

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Barrett and Waterhouse Journal of Cardiovascular Magnetic Resonance 2012, 14(Suppl 1):P146http://www.jcmr-online.com/content/14/S1/P146

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