151,700 -575,400

1,080,000+as of 10/14/2020

30,000,000 -50,000,000

5,000,000

2,000,000

25,000,000

3,000,000

5,000,000 -8,000,000

5,000,000 -15,000,000

100,000 -150,000

3,798,000 -4,798,000

500,000

500,000,000

50,000,000

2,500,000

1,000,000

32,000,000+so far

THE DEADLIEST PANDEMICSIN HISTORY

AntoninePlague 165 - 180

Plagueof Justinian

483 - 565

JapaneseSmallpoxEpidemic

735 - 737**

BubonicPlague /

Black Death1347 - 1351

1348 - 1665*

1519 - 1520**

The GreatPlagues

MexicoSmallpoxEpidemic

Cocoliztli 1545 - 1547

Yellow Fever 1800 - 1802

Cholera 1817 - 1975***

EuropeSmallpoxEpidemic

1870 - 1875**

WorldwideSmallpoxEpidemic

1877 - 1977**

Spanish Flu 1918 - 1919

RussiaTyphus

Epidemic1918 - 1922

Hong KongFlu

1968 - 1970

HIV/AIDS 1981 - Present

Swine Flu 2009 - 2010

COVID-19 2019 - Present

200

300

400

500

600

700

800

900

1000

1100

1200

1300

1400

1500

1600

1700

1800

1900

2000

A Timeline of theDeadliest Pandemicsin History

Smallpox

Cholera

**Smallpox is most often associated with the 16th century, when it decimated the native population of Mexico. However, it resulted in the most casualties during the last 100 years of its existence. Between 1877 and 1977, smallpox was responsible for the deaths of an estimated 500,000,000 people.

***Like smallpox and the Bubonic Plague, cholera also struck in waves. There were seven major pandemics between 1817 and 1975.

Japanese Smallpox Epidemic

Mexico Smallpox Epidemic

Chile Smallpox Epidemic

Massachusetts Smallpox Epidemic

Boston Smallpox Epidemic

St. Lawrence Valley Smallpox Epidemic

Iceland Smallpox Epidemic

1721 Boston Smallpox Outbreak

New France Smallpox Epidemic

North Carolina Smallpox Epidemic

Charleston Smallpox Epidemic

Pittsburgh Area Smallpox Outbreak

North American Smallpox Epidemic

Pueblo Indians Smallpox Epidemic

First New South Wales Smallpox Epidemic

Second New South Wales Smallpox Epidemic

Plains Indians Smallpox Epidemic

Great Plains Smallpox Epidemic

South Africa Smallpox Epidemic

Victoria Smallpox Epidemic

British Columbia Smallpox Epidemic

Europe Smallpox Epidemic

Worldwide Smallpox Epidemic

First Pandemic

Second Pandemic

Third Pandemic

Fourth Pandemic

Fifth Pandemic

Sixth Pandemic

Seventh Pandemic

1817 - 1824

1829 - 1837

1846 - 1860

1863 - 1875

1881 - 1896

1899 - 1923

1961 - 1975

735 - 737

1519 - 1520

1561 - 1562

1633 - 1634

1677 - 1678

1702 - 1703

1707 - 1709

1721 - 1722

1733

1738 - 1739

1760

1763

1775 - 1782

1788

1789 - 1790

1828 - 1829

1831 - 1834

1837 - 1838

1840

1857

1862 - 1863

1870 - 1875

1877 - 1977

2,000,000

5,000,000 - 8,000,000

Unknown

1,000

1,000

1,300

18,000+

844

Unknown

7,700 - 11,700

730 - 940

Unknown

11,000+

Unknown

Unknown

19,000

Unknown

17,000+

Unknown

Unknown

32,000

500,000

500,000,000

1,000,000 - 2,000,000

100,000

1,000,000+

600,000+

298,600

800,000+

Unknown

Global Pandemics by Death Toll

Worldwide Smallpox Epidemic

Spanish Flu

Plague of Justinian

HIV/AIDS

Bubonic Plague/Black Death

Cocoliztli

Mexico Smallpox Epidemic

Antonine Plague

Cholera

The Great Plagues

Russia Typhus Epidemic

Japanese Smallpox Epidemic

COVID-19

Hong Kong Flu

Europe Smallpox Epidemic

Swine Flu

Yellow Fever

1877 - 1977**

1918 - 1919

483 - 565

1981 - Present

1347 - 1351

1545 - 1547

1519 - 1520**

165 - 180

1817 - 1975***

1348 - 1665*

1918 - 1922

735 - 737**

2019 - Present

1968 - 1970

1870 - 1875**

2009 - 2010

1800 - 1802

500,000,000

50,000,000

30,000,000 - 50,000,000

32,000,000+ so far

25,000,000

5,000,000 - 15,000,000

5,000,000 - 8,000,000

5,000,000

3,798,000 - 4,798,000

3,000,000

2,500,000

2,000,000

1,080,000+ as of 10/14/2020

1,000,000

500,000

151,700 - 575,400

100,000 - 150,000

Resources:www.history.com/news/pandemics-end-plague-cholera-black-death-smallpox www.businessinsider.com/pandemics-that-changed-the-course-of-human-history-coronavirus-flu-aids-plague#smallpox-15th-17th-centuries-3www.news.bbc.co.uk/2/hi/health/4381924.stmwww.en.wikipedia.org/wiki/List_of_epidemicswww.en.wikipedia.org/wiki/Template:COVID-19_pandemic_data

Quarantine was invented during the Black Plague. Sailors would not leave their

ships for 40 days to avoid spreading the illness; the

word comes from the Italian word for 40,

“quaranta.”

*The Great Plagues consisted of around 40 resurgences of the

bubonic plague, primarily in London.

The bacteria Yersinia pestis was

responsible for:

The Plague of Justinian

The Bubonic Plague

The Great Plagues