The Cochrane Library on Wiley InterScience€¦ · Browse About The Cochrane Collaboration (About) 8 4.9. Browse by Topic 9 5. SEARCH THE COCHRANE LIBRARY 10 5.1 Cochrane Advanced

1. INTRODUCTION 1.1 Access to The C 2. REGISTRATION 2.1 Your Personal N2.2 Next time you vis2.3 To Return to The 3. THE COCHRANE 4. BROWSE THE CO 4.1 Browse the Coch4.2 Browse the Data4.3 Browse the Coch (CENTRAL) 4.4 Browse the Coch (Methodology Re4.5. Browse the Coc4.6. Browse the Hea4.7. Browse the NHS4.8. Browse About T4.9. Browse by Topic 5. SEARCH THE CO 5.1 Cochrane Advan5.2 Saving your Sea5.3 MeSH Search 5.4 Search History 6. EXPORTING CIT 7. NAVIGATING YO 7.1 How to link to pri7.2 Displaying the A7.3 Add and view fee 1. INTRODUCTION

The Cochrane Li

The Cochrane Library on Wiley InterScience www.thecochranelibrary.com

User Guide version 1.2

2

ochrane Library 2

2

avigation Bar 4 it 4 Cochrane Library 4

LIBRARY HOMEPAGE 4

CHRANE LIBRARY 5

rane Database of Systematic Reviews 6 base of Abstracts of Reviews of Effects (DARE) 6 rane Central Register of Controlled Trials 7

rane Database of Methodology Reviews views)

7

hrane Methodology Register (CMR) 7 lth Technology Assessment Database (HTA) 8 Economic Evaluation Database (NHS EED) 8

he Cochrane Collaboration (About) 8 9

CHRANE LIBRARY 10

ced Search 10 rch 12

12 14

ATIONS 18

UR WAY AROUND AN ARTICLE 19

mary material 20 nalysis diagrams and tables 21 dback 23

brary User Guide version 1.2 1

The Cochrane Library is now located at www.thecochranelibrary.com and is part of Wiley InterScience. If you are a Cochrane Library user familiar with the database offered previously via Update Software you will find much of the search and navigation functionality of The Cochrane Library on Wiley InterScience remains familiar. New users should find the interface intuitive easy to navigate. This document will provide a guide to help you to navigate and search The Cochrane Library. Before you begin, it will be useful to ensure that you have registered with Wiley InterScience. This is a simple, one-time process that extends a number of benefits and, most importantly, will allow you save your searches. Note: If Wiley has already supplied you with password details for The Cochrane Library you do not need to register again -- just use the access details provided to log in. 1.1 Access To The Cochrane Library You can access

You are a Visitor You are a Personal Subscriber

You are affiliated with Subscribed Institution

You are affiliated with National provision

Search Abstracts Full text

Access via Pay-Per-View

Notes: You will need to use your Wiley InterScience password for your Saved Searches.

Password access. Access to full text is seamless or password-based according to institution’s licence type. You will need to use your Wiley InterScience password for your Saved Searches.

Access to full text is seamless. You will need to use your Wiley InterScience password for your Saved Searches.

• All visitors to The Cochrane Library can search the databases and access Abstract material. • Subscribers and users affiliated with a subscribed institution or National Provision can search the databases and

access full-text material. • For a full list of National Provisions (countries or regions where everyone has access) see:

http://www3.interscience.wiley.com/cgi-bin/mrwhome/106568753/DoYouAlreadyHaveAccess.html 2. REGISTRATION 1) At the Cochrane homepage www.thecochranelibrary.com click on Log In – which appears in the top

right of your screen. 2) This will take you to the Wiley InterScience Homepage.

T

The Cochrane Library User Guide version 1.2

he Cochrane Library Homepage

2

3) Click on the Register Now link 4) Fill out and submit the online registration form – you choose your e-mail login and password.

Set E-mail login and Password You will be taken to the New User Registration page, where you be asked to enter your e-mail login and select and confirm a password. Personal Profile You will also need to provide some basic information about yourself: your name, country, and area of interest. This information is never shared with any third party. Terms of Use To complete the registration you will also need to read and agree to the Wiley InterScience Terms of Use. You can read the Terms of Use by clicking on the link provided. If you would like to receive email updates about new products and functionality provided by Wiley InterScience, check the box provided.

After submitting your registration you wOnce you have validated this by clickingreturn to the site, you need only enter y From the homepage, you can now acceand alert preferences.

The Cochrane Library User Guide

ill receive a one-time authentication e-mail to the address you provide. the link in the message, your new login will be set. Afterward, when you

our e-mail and password to login.

ss your new My Profile area – where you can edit your login, password,

version 1.2 3

2.1 Your Personal Navigation Bar

Once logged in you’ll see your own navigation bar at the top of the screen. This include drop down links to any titles and articles that you have saved – a quick and easy way of accessing your favourite content

2.2 Next time you visit:

HINT: Next time you log in to Wiley InterScience check the ‘Remember Me’ box. This saves your login and password details in a cookie on your computer system. This means next time you visit The Cochrane Library from the same computer, you needn’t login. Don’t use this option if you are on a shared or public computer.

2.3 To Return To The Cochrane Library

TO RETURN TO THE COCHRANE LIBRARY To return to the Cochrane homepage use the search box on your screen; make sure you check the Publications Titles radio button, type Cochrane into the search box and click ‘Go’.

ClickLibra

The Cochrane ry link.

The Cochrane Library User Guide version 1.2 4

3. THE COCHRANE LIBRARY HOMEPAGE You are now on The Cochrane Library homepage. Here you will find links to Browse and Search functionality, and links to more information about the Collaboration and Product descriptions. The interface is intuitive, but its key components are noted below.

TO SEARCH THE COCHRANE LIBRARY The SEARCH IN THIS TITLE feature will allow you to search one or more of The Cochrane Library databases. All your search links can be found in this box. You can choose to perform a Quick Search, using the search box provided, or you can link to a MeSH (Medical Subject Headings) indexing Search,

HINHoLibDa

HINT: Save Title to My Profile will save the Cochrane Library to your drop down navigation bar and to your My Profile area in Wiley InterScience. This will make it quicker to access The Cochrane Library next time you visit

BROWSE:You can browse the different databases that make up the library by selecting the links here. Mouse over for the full name of the database

ALL CONTENT SEARCHUse this button to search across the entire Wiley InterScience platform of content.

You can link to more information about The Cochrane Library using these links.

an Advanced Search, or go to your Search History, Saved Searches and Search Tips.

T: You can return to the mepage of The Cochrane rary by clicking the Title or tabase Home.


4. BROWSE THE COCHRANE LIBRARY

Cochrane Reviews | DARE | CENTRAL | Methodology Reviews | Methodology Register | HTA | NHS EED | About | Topics You can Browse articles by clicking on the link to the database you wish to browse. 4.1. Browse The Cochrane Database of Systematic Reviews (Cochrane Reviews)– will present alphabetical list of all Systematic Reviews and Protocols. Use the alpha-bar to view articles, alphabetically/numerically by title. Use the scroll bar on the right to scroll down to view all titles beginning with that letter. Click on the chosen link to go to the abstract of that review/protocol.

What is a Systematic Review?A systematic review identifies an intervention for a specific disease or other problem in health care, and determines whether or not this intervention works. To do this authors locate, appraise and synthesise evidence from as many relevant scientific studies as possible. They summarise conclusions about effectiveness, and provide a unique collation of the known evidence on a given topic, so that others can easily review the primary studies for any intervention. Systematic reviews differ from other types of review in that they adhere to a strict design in order to make them more comprehensive, thus minimising the chance of bias, and ensuring their reliability.

A key for the status of the reviews is:

= A full Review, complete with results and discussion, meta-analysis and an odds-ratio diagram for the review.

= A Protocol. The outline of reviews in preparation, including the background, rationale and methods.

= A full Review that also contains commentary/criticism. Readers can submit comments, which are incorporated into the review together with answers and feedback from the review authors.

= A new Protocol or review that has been published in the most recent quarter.

= A Review that has been updated in the most recent quarter. = A Review or Protocol that has been withdrawn – usually due to

lack of activity or update. Reasons for withdrawal are specified in the article.

4.2 Browse Database of Abstracts of Reviews of Effects (DARE) Presents an alphabetical list of all articles that have a structured and/or provisional abstract in the database. Use the alpha-bar to view article titles alphabetically. Use the scroll bar on the right to scroll down to view all articles beginning with that letter. Click on the chosen link to go to the abstract for that article.

What is the Database of Abstracts of Reviews of Effects? DARE includes structured abstracts of systematic reviews from around the world, which have been evaluated by reviewers at the National Health Service Centre for Reviews and Dissemination in the UK. Only reviews that meet minimum quality criteria are included in DARE. These reviews cover topics that have yet to be addressed in Cochrane reviews.


4.3 Browse The Cochrane Central Register of Controlled Trials (CENTRAL) Because CENTRAL is so large (with in excess of 405,000 records) it automatically takes you to a search screen, where your search is limited to CENTRAL results.

What is the Central Register of Controlled Trials? CENTRAL includes details of published articles taken from bibliographic databases, and other published and unpublished sources. CENTRAL records include the title of the article, information on where it was published (bibliographic details) and, in many cases, a summary of the article. They do not contain the full text of the article. Trials are identified from multiple sources, including searches of bibliographic databases, hand searches of many hundreds of journals and conference proceedings, and searches of other trial registers.

4.4 Browse The Cochrane Database of Methodology Reviews (Methodology Reviews) Presents an alphabetical list of all Methodology Reviews and Protocols. Click on the chosen link to go to the abstract of that review/protocol

4.5. Browse the Cochrane Methodology Register (CMR) Presents an alphabetical list of articles on the science of conducting controlled trials and reviews.

What is a Methodology Review? Cochrane Methodology Reviews are full-text systematic reviews of methodological studies. Highly structured and systematic, evidence from methodological research is included or excluded on the basis of explicit quality criteria, thus minimising bias. Each review covers a specific and well-defined area of methodology. Data from studies are often combined statistically to increase the power of the findings of numerous studies, which on their own may be too small to produce reliable results. In such cases, the review may also include graphs presenting the data from each individual study. Protocols provide place-markers for reviews, which are currently being written. They summarise the background and the rationale of the review.

What is the Cochrane Methodology Register (CMR)? The Cochrane Methodology Register is a bibliography of publications which report on methods used in the conduct of controlled trials. It includes journal articles, books and conference proceedings; these articles are taken from the MEDLINE database and from hand searches. The database contains studies of methods used in reviews and more general methodological studies which could be relevant to anyone preparing systematic reviews. CMR records contain the title of the article, information on where it was published (bibliographic details) and, in some cases, a summary of the article. They do not contain the full text of the article.

4.6. Browse the Health Technology Assessment Database (HTA) Presents alphabetical list of all articles that have a record in the database. Use the alpha-bar to view article titles alphabetically. Use the scroll bar on the right to scroll down to view all articles beginning with that letter. Click on the chosen link to go to the record for that article.

4.7. Browse the NHS Economic Evaluation Database (NHS EED) Presents alphabetical list of all articles that have a structured and/or provisional record in the database. Use the alpha-bar to view article titles alphabetically. Use the scroll bar on the right to scroll down to view all articles beginning with that letter. Click on the chosen link to go to the record for that article.


What is the Health Technology Assessment Database? (HTA) Contains information on healthcare technology assessments. The database contains details of ongoing projects and completed publications from health technology assessment organisations. HTA records follow a standard structure. Some records contain the title of the project, with the name of the centre responsible and an indication of where further details can be obtained. Other records contain publication details, with structured abstracts where available. Records do not, in either case, contain the full text of the report.

What is the NHS Economic Evaluation Database? (EED) Contains structured abstracts of articles describing economic evaluations of health care interventions. Articles are identified by searching through key medical journals, bibliographic databases and less widely available literature. Papers included if they provide a comparison of treatments and examine both the costs and outcomes of the alternatives. The database also includes bibliographic details of articles examining relevant topics, and short abstracts of studies originally included in the Department of Health Register of Cost-Effective Studies. Records do not contain the full text of the original article.

4.8 Browse About The Cochrane Collaboration and the Cochrane Collaborative Review Groups (About)

Presents a list of articles that provide more information about the Collaboration, including details on the Steering Group, Fields, Methods Groups, Networks and Centres.


4.9. Browse by Topic. You can also browse through the topic lists of the different Cochrane review groups. To do this select Browse articles by topic.

.

You will be taken to a list of subject fields relating to that given topic area, in which reviews are available. The number in brackets beside the subject field denotes the number of reviews published in The Cochrane Library in that subject field.

Select the topic you are interested in from the drop down list

Select the subject area you are interested in, and you will be provided with a list of links to all the reviews in The Cochrane Library that match that subject area.


5. SEARCH THE COCHRANE LIBRARY The Cochrane Library allows for a number of different search types, designed to allow you to be as broad, or as narrow as your information requirements dictate. You can conduct a quick search of The Cochrane Library using the quick search box. Apply fields by using the drop-down menu. For more complex searching you can use the links to the Advanced search function, MeSH Search and Search History. 5.1 Cochrane Advanced Search

Refine your search by what databases you would like to search. You can choose ‘all’ – the default search - or select one or more titles by clicking the relevant boxes.

You can also limit your search by date range. You can also refine your search by what type of records you

would like to search. Again the default is ‘All’; but if you just want to search new records, updated records, etc you can choose to set these parameters by clicking the relevant radio buttons.

To execute The Cochrane Library Search, users can specify search expressions in the boxes provided, which may be combined by selecting “And,” “Or,” and “Not ” from accompanying pull-down menus on the left. You can limit your search by fields what you want it to search (Full text, Title, Author, Abstract, Keywords, Tables, Publication Type, Source and DOI), by using the pull-down boxes on the right. Within each search expression, common search syntax such as wild character asterisks, Boolean operators, parenthetical brackets, and quotation marks are fully supported.


An example You want to search for information on atypical drugs that have antipsychotic properties used in the treatment of schizophrenia. One means of searching for this information is to enter the following:

Your search terms are connected by ‘AND’

You have selected to search across all records.

You have selected to search across all databases in the library.

You have selected to search across all text in The Cochrane Library for the terms: schizo*, drugs, atypical and antipsychotic. You have also truncated schizo* to search both schizophrenia and schizophrenic.

The results are displayed as follows:

You can toggle between results listed for the different databases in the Cochrane Library here. The number in brackets indicates the number of records that match your search in that database. You can see here that there are 53 records in Systematic Reviews, 17 records in DARE and so on. Click on the link to see the results for that database

Use these links to restrict your search results to Reviews only, or Protocols only.

Use these links to sort your search results by Title, Match%, or Year.

25 results are listed on every page; go to more results using this link

Use these links to save your search (see over) or edit your search.


5.2. SAVING YOUR SEARCH If you want to save your search you can do so by selecting the Save Search button.

Your search will be saved ready for you to run it again when desired. You can also activate your alerting service, which will email you each time a new article is published which meets the parameters of your search.

Once your alert is on, the alert status icon will cAlert. If you want to stop receiving alerting emaialert.

Click Run to run your search again.

5.3. MeSH SEARCH Keywords drawn from the MeSH Thesaurus published by the US Library of Medicine have beemany, but not all, records in The Cochrane Library. The MeSH Thesaurus is organized hierarchically in 'trees', with the lower levels of the trees cospecific terms. The MeSH search allows searching of the databases in The Cochrane Library usterms and tree structures.

To activate a MeSH search click on the MeSH search link in your search box.


Click Activate Alert to set your email alerts for

hange to Stop ls click on stop

n attached to

ntaining more ing the MeSH

12

Step 1: Using the MeSH Thesaurus The Permuted Index is an index of all the words that appear in the MeSH thesaurus. It is used to locate specific MeSH headings:

Click on a MeSH term to display the MeSH tree(s) contadescription ‘Kidney’ will return a screen displaying your M Step 2: Finding your way around MeSH trees

ii. Select your search option

All MeSH headings containbold entry for that word in alp By browsing these headininterested in. Some terms areferences for that term. Creferenced section of the Pe

‘Search this term only’ will search just for the selected term (the one in red)

Once you have selected the term you want to search under, you can choose one of two options.


Open the MeSH search screen by clicking on the MeSH search in your search box Search the Permuted Index by entering one word and clicking on Thesaurus. For instance if I were to search for the term ‘Kidney’ – there are 29 descriptors and 44 cross-references returned for that word.

ining that term. For instance, a click on the MeSH

eSH trees:

i. Select your search term

ing the word ‘Kidney’ are displayed under the habetical order.

gs, locate the specific MeSH term you are re followed by 'see' and the appropriate cross-lick on these terms to jump to the cross-

rmuted Index.

The MeSH tree(s) containing the selected MeSH heading are displayed once a heading has been selected from the Permuted Index. The MeSH trees allow expanding or narrowing the scope of the search, by selection of broader or narrower terms.

To move up to a more general level in a MeSH tree, click on a term that sits higher in the tree. More specific terms are displayed immediately underneath, and just to the right of your selected term, which appears in red.

Urogenital System is the broadest term in this tree. If you wanted to move up a level in the MeSH tree and expand the range of your search significantly, you could select this term

Your search term is highlighted in red. If you wanted to narrow your search down from this term, you could click on one of the narrower terms listed immediately below and slightly to the right.

The explode option will automatically include all narrower terms below the term highlighted in your search as well. This will maximize the number of records retrieved. For some terms you will have more than one tree. You can select whether you want to explode your search to include all trees, or just those selected by checking the box next to them.

13

iii. Choose search restrictions (if any)

5 Sy1 T FS

Once you have selected your search option, decide whether you want to restrict your search by additional qualifiers that can be selected from the drop down box provided, or typed into the search box to the right of the drop down box. iv. Search Hit ‘View Results’ to conduct your search.

v. ResultsResults are presented (see p.11 for more details on search results screen)

.4. Search History earch history provides a history ofour searches for future use in othe2, or you can use the Save Search

he search history function is a goo

or instance if you were seeking infearch The Cochrane Library funct

The Cochrane Library User G

.

your searches in your current session on Cochrane. If you want to save r sessions you can either use the Save Search function described on page Strategy function in search history (see p. 17).

d way of combining different searches to maximize your search efficiency.

ormation on childhood obesity, you could run the following search on the ion:

(obesity OR obese)

uide ver

The second line could relate to the ‘childhood’ part of your search.

This returns a total of 4552 hits across all the databases

sion 1.2 14

T#

Y

(child* OR infant* OR pediatric)

hen, by going to Search History, you can 1, #2 and so on.

our combined search will then come up in

The Cochrane Library User Guide ver

HINT – your search for the word pediatric will also retrieve records containing the variant spelling paediatric.

This returns a total of 52795 hits across all the databases

combine these searches. Firstly, your searches will be numbered,

s

your Search History.

The combined search (#1 AND #2) returns 496 results across all the databases. Your combined search history is now listed and you just need to click on it to run it.

ion 1.2 15

You can run a MeSH search using the descriptor ‘Obesity’.

Search – exploding all trees.

This returns a total of 2617 hits across all the databases.

Next, search for the MeSH term Obesity OR the word Obesity as a normal text word. This ensures that you find relevant records that aren’t attached to the MeSH term.

This returns a total of 4565 hits across all the databases.

#1 OR #4.

Finally, refine your search further by combining lines 2 and 5.

The final result of your search is 504 across all the databases.


You can save this whole record of Search History, which with sophisticated search technique can add up to hundreds of lines of search, by clicking on the button ‘Save Search Strategy’

A pop-up box will appear, prompting you to name and add comments to your search.

Save your Search history by clicking this button

Now, when you return to your saved searches you will see your saved search history. Click run located to the right of your search name to return to that

search strategy.

When you run your Saved Search Strategy, you will be returned to the saved search history.

HINT – you don’t receive email alerts for saved search histories – but you can for individual searches (with the exclusion of your combined searches e.g. #1 AND #2). If you haven’t already saved them, simply run them from your Search History and then click on Save Search on their results page.


6.0. EXPORTING CITATIONS To export citations for your reference databases (e.g. EndNote), select which records you would like citations exported from by clicking on the boxes next to them. If you want to export all on that page, click the ’Select All’ option at the bottom of the page. To export those selected, click the ‘Export Selected Citations’ button.

A pop up box will appear prompting you to select your Export

MULTIPLE RESULTS PAGES The number of citations you export is not restricted. For multiple results pages, check items you want to export, then continue process for all page displays.

Sy

Select your Export Type – choose between Citation only, or abstract and citation.

You will be prompted to either open or save the file:


Type and File Type from the drop down boxes:

elect your File Type, depending on whether our are working on a PC, Mac or Unix/Linux

18

7.0 NAVIGATING YOUR WAY AROUND AN ARTICLE When you open a review in The Cochrane Library it is displayed in frames. Below is an example of a Complete Review from the Cochrane Database of Systematic Reviews.

Header material includes the DOI (Digital Object Identifier), when the article was first published, the date of the most recent substantive amendment, and the correct method of citing the article.

The title will also tell you the status of the article – whether it’s a complete review or a protocol

A Table of Contents for the article appears on the left of your screen. You can link directly to the section of the article that interests you using these links.

The blue reference links will take you directly to that reference in the article’s bibliography.

You can also link to figures and tables associated with the article.

You can choose to export the citation for this article from this TOC.

You can open, print and save PDFs of Reviews using the PDF link at the top of the Table of Contents. This is a good way of determining how many pages a review has before you print – this one has 131!

You can also use the PDF search feature to search the entire document for a particular word or phrase.


7.1 How to link to primary material cited:

This will take you to a page with links to Title and Abstract indices for this citation:

Ensure you are in the References section of your review.

Click on ‘Links’ next to the cited article you would like to link to.

Choose the link to the indexing service you wish to use to link to title, abstract and linking information for the paper.

The Cochrane Library User Guide
version 1.2 20

7.2. Displaying the CDSR Odds-Ratio diagrams and tables An integral feature of The Cochrane Database of Systematic Reviews is the odds-ratio figures provided for each review. These diagrams provide a clear and concise visual representation of the analyses of results for each trial included in a review, each outcome considered and any meta analysis of trials data.

A sThfamovhtt

Use the links to Figures and Tables to display pop-up screens of these features.

creen containing Odds-Ratio diagrams will appear. The ‘Tables’ link will take you to associated tables. e Odds- Ratio diagrams are a very convenient tool – at first they may appear complicated, but as you become iliar with them and what they represent you will find that they are an invaluable means of providing a reliable

erview of the evidence. A very useful training guide on interpreting these diagrams is available at: p://www.york.ac.uk/inst/crd/clibsec3.pdf


To view an interactive version of this diagram, click on the ‘Show Statistical Analysis’ link.

This will display a screen that allows you to manipulate how you want the data to be displayed.


7.3. Add and view feedback Select a Cochrane Review or Methodology Review. Then select the link ‘Add/View Feedback’ in the left hand table of contents for the selected record.

To ad‘Add/Vpop-ulocate

d your own comments or criticisms, select the iew Feedback to this review/protocol’ link in the

p window displaying the feedback. This link is d at the top and bottom of the pop-up window.

Feedback associated with the selected review or protocol will be displayed in the pop-up window that is launched.


CONTACT WILEY INTERSCIENCE North, Central and South America John Wiley & Sons, Inc. Attn: Wiley InterScience Coordinator Subscription Department 111 River Street Hoboken, NJ 07030 USA Toll-free US only: 1.866.465.3817 Outside US: 1 (201) 748.6645 Option 4 Fax: 1 (201) 748.5715 e-mail: [email protected] European Union, Rest Of World: John Wiley & Sons, Ltd. Attn: Wiley InterScience Coordinator Journals Fulfillment 1 Oldlands Way Bognor Regis West Sussex PO22 9SA UK Tel. 44 (0) 1243.843.397 Fax. 44 (0) 1243.843.232 e-mail: [email protected]


Documents

The Cochrane Library on Wiley InterScience€¦ · Browse About The Cochrane Collaboration (About) 8 4.9. Browse by Topic 9 5. SEARCH THE COCHRANE LIBRARY 10 5.1 Cochrane Advanced