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The Center for Nanoscience and Nanotechnology Scientific Report 20013–2014 The Center for Nanoscience & Nanotechnology SCIENTIFIC REPORT 2013–2014

The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

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Page 1: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

The Center for Nanoscience and N

anotechnology Scientific Report 20013–2014

The Center for Nanoscience

& NanotechnologySCIENTIFIC REPORT 2013–2014

Page 2: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky
Page 3: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

Center forNanoscience and Nanotechnology

SCIENTIFIC REPORT2 0 1 3 - 2 0 1 4

Page 4: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

2 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Acknowledgements

We are grateful for the support of numerous individuals and organizations:

The Chaoul Center for Nanoscale Materials and Systems

The Marian Gertner Institute for Medical Nanosystems

Vinci Technologies (Mr. Renaud Presberg)

Mr. Robert Goldberg

James Russell DeLeon - The Center for Nanostructuring

The Jack H. Skirball National Center for Biomedical Nanoscience

Nanotechnology Research Fund in Cooperation with Clal Biotechnical Industries

The Ilona Rich Institute for Nanoscale Bioscience and Biotechnologyv

The Dr. Teodoro Jack and Dorothea Krauthamer Laboratory for Scanning Electron Microscopy

A.V.B.A. Students Laboratory for Electron Beam Lithography

Infrastructure Equipment for Nanotechnology Research - Wolfson Family Charitable Trust ,UK

The Raymond and Beverly Sackler Chair in Clusters and Nanoparticles

The Edouard Seroussi Chair for Protein Nanobiotechnology

The Herman and Kurt Lion Chair in Nanosciences and Nanotechnologies

The Bernard L. Schwartz Chair and Program in Nano-scale Information Technology

Support for Nanotechnology Research donated by The Gilman Foundation

Walanpatrias Stiftung

Pa'amei Tikva Nanotechnology Research Fund (Israel 2004) LTD

Shlomo Eliahu

Scholarships

The Buchman Heyman Foundation

The Herb and Sharon Glaser Foundation

The Cohen Family Doctoral Fellowship for the study of Nanoscience

Mr Ezekiel Solomon

Since 2007 the center is generously supported by Israel Nanotechnology National Initiative (INNI) program, founded by TELEM (2007-2016)

Page 5: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

3 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Contents

Acknowledgements 2

Overview 5

Center Staff and Services 5

Researchers

Dr. Tamir Tuller 9

Dr. Sharly Fleischer 10

Dr. Yael Roichman 11

Prof. Diana Golodnitsky 12

Prof. Emanuel Peled 13

Prof. Eran Rabani 14

Prof. Haim Diamant 15

Prof. Oded Hod 16

Prof. Ori Cheshnovsky 17

Prof. Yoram Cohen 18

Dr. Roey Amir 19

Dr. Alon Bahabad 20

Dr. Yossi Lereah 21

Prof. Jacob Scheuer 22

Prof. Amir Boag 23

Prof. Gil Rosenman 24

Prof. Yosi Shacham 25

Prof. Abdussalam Azem 26

Dr. Avigdor Eldar 27

Dr. David Sprinzak 28

Dr. Iftach Nachman 29

Dr. Tal Dvir 30

Dr. Vered Padler-Karavani 31

Prof. Alexander Kotlyar 32

Prof. Itai Benhar 33

Prof. Judith Rishpon 35

Prof. Rimona Margalit 36

Dr. Oswaldo Dieguez 37

Prof. Ilan Goldfarb 38

Prof. Noam Eliaz 39

Prof. Shachar Richter 40

Page 6: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

4 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Natan T. Shaked 41

Prof. Slava Krylov 42

Dr. Yair Shokef 43

Dr. Noam Shomron 44

Dr. Inna Slutsky 45

Dr. Roy Beck 46

Prof. Eli Eisenberg 47

Prof. Yoram Dagan 48

Prof. David J. Bergman 49

Prof. Yael Hanein 50

Publications 53

Collaborative Projects 67

Cooperation with the Industry 70

Staff 71

Page 7: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

Their expertise, energy and dedication are the primary origin for the success of the Center. Our second resource is a state of the art facility boasting some of the most advanced micro and nano instrumentation in Israel. Since 2003 the Center was able to continue to expand its core facilities. These facilities are managed with the mission to provide TAU researchers with the best resources possible. We are also committed to make these resources and the knowhow developed at the Center open and accessible to Israeli Industry.

The Center is also active in organizing various social and scientific activities including our annual workshop, monthly seminars, monthly nano beer events, student exchange program and more.

List of External Users

Active Implants, ADT, Applied Materials, AudioPixels, CartiHeal, Cellera, Cima Nanotech, City Studios, Civan Technologies, EL-OP, IAI, IMH, Kadoor Microelectronics, Maradin, Mellanox Technologies, MEMS&Optomechanics Design, Microtech Medical Technologies, Mizur Technologies, Noam Urim Enterprises, Orbotech, Pebbles, Physical Logic, PicoTech, Raicol Crystals, Shiba Hospital, SOREQ NRC, StoreDot, Suron, Tortech Nano Fibers – Plasan, UTILIGHT, and VISIC. In addition our facility gives services to users from other academic institutes: Bar Ilan University, Ben Gurion University, Technion, Hebrew University, Weizmann Institute, Ariel College, University of Antwerpen and IIT-Genova.

Our industrial services include small scale processing and characterization and large scale R&D projects.

More details: http://nano.tau.ac.il/mncf/

Tel Aviv University Center for nanoscience and nanotechnology was established in 2000 as the first Israeli center of its kind. We have expanded and developed markedly since then. With 70 affiliated research groups, a proffesional staff of eight researchers and scientists, and a state of the art central facility, the Center is well positioned to support the outstanding research performed at Tel Aviv University. Over the years we have also strengthened our ties with the Israeli industry. The Center provides extensive industrial services to a growing number of companies: From small startups to large industries. As a center of excellence we also maintain close links with leading international institutes. We maintain our ongoing cooperation with Northwestern University. Last year we have partnered with Ludwig-Maximilians-Universität München for a student exchange program. Recently, we joined forces with Tsinghua University to build a new joint research center – XIN (new in Chinese). After 13 years of constant growth, the Center has positioned itself as an important assest to Tel Aviv University researchers and the Israeli Industry.

This report provides a brief overview of current activities at the Center. We hope you will find the information useful in identifying new partnerships, resources and ideas. Full information about the Center is constantly updated and is available on our web site at www.nano.tau.ac.il.

Center Staff and Services

Tel Aviv University Center for Nanoscience and Nanotechnology prides itself with two extraordinary resources. Foremost is our 8 strong team of scientists and engineers complemented with a dedicated administrative and fiscal support personnel.

Overview

Tel Aviv University Center forNanoscience & NanotechnologyPowering Innovation

Page 8: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

6 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

“It's true that the original idea was mine, but what you see today is the work of probably tens of thousands of the world's best engineers, all concentrating on improving the product, reducing the cost, things of that sort” – Jack Kilby

Jack Kilby (recipient of the 2000 Nobel prize in physics) is credited with the invention of the first integrated circuit while working at Texas Instruments in 1958. He was also the inventor of the handheld calculator and the thermal printer.

The MNCF team: Gidon Jacob (Equipment Engineer), Valery Garber (Project Manager), Youry Borisenkov (Process Engineer), Inna Veksler (Fiscal Specialist), Dr. David Schreiber (Senior Process Engineer), Dr. Nava Ariel-Sternberg (General Manager), Dr. Artium Khatchtouriants (AFM Specialist), Dr. Yigal Lilach (SEM and particle lithography Specialist) and Alex Epstein (Equipment Engineer).

Full information about our facilitys is available at: http://nano.tau.ac.il/mncf/

Page 9: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS(sorted by cademic unit)

Page 10: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky
Page 11: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

9 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Tamir Tuller

AFFILIATION: Bio-medical Engineering

TEL: (972)-3-6405836

EMAIL: [email protected]

WEB: www.cs.tau.ac.il/~tamirtul/

Research TitleUnderstand, model, and engineer gene expression

Selected Publications:1. Ben-Yehezkel T, Zur H, Marx T, Shapiro E, Tuller T.(2013). Mapping

the translation initiation landscape of an S. cerevisiae gene using fluorescent proteins. Genomics. 102(4):419-29.

2. Dana A, Tuller T. (2012). Determinants of translation elongation speed and ribosomal profiling biases in mouse embryonic stem cells.

3. PLoS Comput Biol. 8(11):e10027554. Tuller T, Veksler-Lublinsky I, Gazit N, Kupiec M, Ruppin E, Ziv-Ukelson

M. (2011). Composite effects of gene determinants on the translation speed and density of ribosomes.Genome Biol. 3;12(11):R110

5. Tuller T, Carmi A, Vestsigian K, Navon S, Dorfan Y, Zaborske J, Pan T, Dahan O, Furman I, Pilpel Y. (2010). An evolutionarily conserved mechanism for controlling the efficiency of protein translation. Cell. 141(2):344-54.

6. Tuller T, Waldman YY, Kupiec M, Ruppin E. (2010). Translation efficiency is determined by both codon bias and folding energy.Proc Natl Acad Sci U S A. 107(8):3645-50.

Research DescriptionThe general aim of our lab is to understand, model, and engineer gene expression. To this end, we employ a multidisciplinary approach via integrating tools from disciplines such as computer science, biochemistry, engineering, statistics, synthetic biology, and molecular evolution.Few more specific aims includes: Computational Modeling of Gene Expression - We develop computational predictive models to mathematically analyze and simulate the different stages of gene expression, focusing on gene translation. The models are based on biophysical and stochastic aspects of this process.Engineering of Gene Expression - We devise supervised and unsupervised approaches for engineering gene expression for various biotechnological objectives.Deciphering the Gene Expression Code - We perform large scale analyses of genomic data to discern the way various aspects of gene expression are encoded in the transcript.

Page 12: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

10 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Sharly Fleischer

AFFILIATION: Chemistry

TEL: (972)-3-6408254

EMAIL: [email protected]

WEB: https://sites.google.com/site/terahertzandultrafastlab/

Research TitleUltrafast Terahertz and optical coherent control of molecules

Selected Publications:1. Sharly Fleischer, Robert. W. Field, and Keith A. Nelson, Commensurate

two quantum coherences induced by time delayed THz fields, Phys. Rev. Lett. 109, 123603 (2012).

2. Sharly Fleischer, Yan Zhou, Robert W. Field, and Keith A. Nelson, Molecular orientation and alignment by intense single-cycle THz pulses, Phys. Rev. Lett. 107, 163603 (2011).

3. Sharly Fleischer, Yuri Khodorkovsky, Ilya Sh. Averbukh, and Yehiam Prior Controlling the Sense of Molecular Rotation.New J. Phys. 11, 105039 (2009).

4. Sharly Fleischer, Ilya Sh. Averbukh, and Yehiam Prior, Selective Alignment of Molecular Spin Isomers. Phys. Rev. Lett. 99, 093002 (2007).

5. Sharly Fleischer, Ilya Sh. Averbukh, and Yehiam Prior, Isotope-selective laser molecular alignment, Phys. Rev. A. 74, 041403 (2006).

Research DescriptionJust as light is affected by matter it interacts with in traditional spectroscopy, the state of the matter can be altered by light andcoherently driven to yield a desired goal - a field known as 'coherent control'. Interested in both these mutually complementing processes, we use

intense femtosecond light fields in the terahertz (THz fields, 1012 Hz) and in the visible/near-IR (optical fields, 1015 Hz) to coherently control and spectroscopically study the dynamics of molecules upon photochemical reactions. We develop new control schemes based on combined excitations by THz and optical fields acting as two distinct molecular handles, and utilize them for inducing unique angular distributions in molecular ensembles and study them using advanced ultrafast spectroscopic methods. With the help of intense light fields, we wish to control and study molecules with increasing size and complexity, with the goal of applying these methods to big molecules and nanostructures of chemical and biological interest.

Page 13: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

11 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Yael Roichman

AFFILIATION: Chemistry

TEL: (972)-3-6405848

EMAIL: [email protected]

WEB: lorentz.tau.ac.il/~yael/

Research TitleExperimental studies of soft matter with holographic optical tweezers

Selected Publications:1. Independent and simultaneous three-dimensional optical trapping

and imaging. Maya Yevnin, Dror Kasimov, Yael Gluckman, Yuval Ebenstein, and Yael Roichman, Biomedical Optics Express, in press (2013).

2. Myosin II does it all: Assembly, Remodeling, and Disassembly of actin networks are governed by myosin II activaty, Yaron ideses, Adar Sonn-Segev, Yael Roichman, and Anne bernheim-Groswasser, Soft matter, in press DOI10.1039/C3SM50309G (2013).

3. Accurate holographic imaging of colloidal particle pairs by Rayleigh-Sommerfeld reconstruction, David Kapfenberger, Adar Sonn-Segev, and Yael Roichman, Optics Express, 21 , pp.12228-12237, (2013).

4. Hydrodynamic Pair Attractions between Driven Colloidal Particles, Yulia Sokolov, Derek Frydel, David G. Grier, Haim Diamant, and Yael Roichman, Phys. Rev. Lett., 107, 158302, (2011).

5. Holographic assembly of quasicrystalline photonic heterostructures, Y. Roichman and D. G. Grier, Optics Express 13, 5434-5439 (2005). (cond-mat/0506283)

Research DescriptionIn our group we are interested in understanding the principles governing the behavior of system out of thermal equilibrium. Toward this goal we use a combination of optical imaging and optical manipulation to probe and image soft materials and complex fluids. We believe that by studying many model systems far from thermal equilibrium, in detail, we will be able to see emergent universalities. In the past few years we have studied two different systems driven out of equilibrium in a different way: optically driven colloidal suspensions, and in-vitro cytoskeleton networks containing molecular motors. Technically, the experimental work in the group is based on video microscopy, particle tracking and image velocimetry to study the dynamics and kinetics of particles in our model systems, and microrheology to characterize their mechanical properties. In addition, we develop optical imaging techniques with improved resolution and speed, and combine various 3D imaging techniques with optical trapping and manipulation.

Page 14: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

12 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Diana Golodnitsky

AFFILIATION: Chemistry

TEL: 972-3-6407820

EMAIL: [email protected]

WEB: http://www2.tau.ac.il/nano/researcher.asp?id=dbjhegflh?

Research TitleNano Materials and thin films for electrochemical energy Storage and conversion

Selected Publications:1. K. Goldshtein , D. Golodnitsky, Y. Lareah, L. Burstein, E. Peled Study

of Polymer Electrolytes with Grafted Au-gFe203 Nanoparticles, International Journal of Hydrogen Energy,2013, in press

2. R. Blanga, D. Golodnitsky, G. Ardel, K. Freedman, A. Gladkich, Yu. Rosenberg, M. Nathan, and E. Peled. Quasi-solid polymer-in-ceramic membrane for Li-ion batteries, ElectrochimicaActa, 114 (2013) 325-333

3. R. Hadar, D. Golodnitsky, H. Mazor, T. Ripenbein, G. Ardel, Z. Barkay, A. Gladkich,E. Peled. Development and Characterization of Composite YSZ-PEI Electrophoretically Deposited Membrane for Li-Ion Battery, J Phys. Chem. B, 117 (2013) (6), 1577–1584

4. H. Mazor, D. Golodnitsky, L. Burstein, A. Gladkich, E. Peled, Electrophoretic deposition of lithium iron phosphate cathode for thin-film 3D-microbatteries, Journal of Power Sources198, (2012) Pages 264-272

5. K. Goldshtein, D. Golodnitsky E. Peled, L. Adler-Abramovich, E. Gazit, S. Khatun, P. Stallworth, S. Greenbaum. Effect of peptide nanotube filler on structural and ion-transport properties of solid polymer electrolytes Solid State Ionics 220 (2012) 39–46

Research DescriptionGiven that lithium-ion and lithium air batteries are the preferred choice for EVs and plug-in applications for the next 10–15 years, the focus is on improving their safety and performance. New, higher-capacity

materials are required in order to address the need for greater energy density, longer cycle life and safer high-power operation. Silicon offers the highest gravimetric and volumetric capacity as an anode material (e.g. Li22Si5: nearly 4,200mAh/g, 9,800mAh/mL). The lithium-rich silicon compounds have high melting points.Their higher

working potentials (vs. Li) eliminate the possibility of metallic-lithium deposition due to overcharge. Silicon is the second-most abundant element in the earth’s crust, and it is environmentally benign. Unfortunately, Si-based electrodes typically suffer from large volume changes (up to 420%) during insertion and extraction of lithium. This is followed by cracking and pulverization of silicon, which in turn, leads to the loss of electrical contact, unstable SEI and eventual capacity fading.We develop the methods of attachment of silicon nanoparticles to carbon nanotubes (multi-wall carbon nanotubes (MWCNT)) with the purpose of creating silicon anodes supported by a strong, rigid and high-electrically-conducting matrix. We study the process of formation of the protective SEI layer on the anode nanoparticles and test small laboratory-prototype cells with advanced anodes. Our second project is aimed at understanding ion transport and the development of solid polymer electrolytes (PE) with high ionic conductivity for thin-film batteries, capacitors, electrochromic, electronic and biomedical devices. This is by now an old theme, and there has been much research carried out over the years. Until recently, the ionic conductivity has been thought to be closely connected to the segmental relaxation of the host polymer.Maximizing the ionic conductivity of PEs was achieved by maximizing the amorphicity of the polymer and lowe ring its glass transition temperature. However, the problem of obtaining polymer electrolytes with sufficiently high conductivity (0.1S/cm) persists and is still relevant from both scientific and technological points of view. Our current work exploits novel ideas of structuring under magnetic and strong electric fields of ionically-conducting polymers modified by, or grafted with magnetic nanoparticles. On the basis of the data accumulated so far, we claim that success in the development of highly-conductive polymer electrolytes depends on finding a correct way to form new ordered (rather than disordered) structures with diffusion of the mobile ions decoupled from relaxation of the host polymer.

Page 15: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

13 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Emanuel Peled

AFFILIATION: Chemistry

TEL: 972-3-6408438

EMAIL: [email protected]

WEB: nano.tau.ac.il/peled

Research TitleNano materials and thin films for electrochemical energy storage and conversion

Selected Publications:1. H. Mazor, D. Golodnitsky, L. Burstein, A. Gladkich, E. Peled,

Electrophoretic deposition of lithium iron phosphate cathode for thin-film 3D-microbatteries, Journal of Power Sources 198, (2012) 264-272.

2. K. Goldshtein, D. Golodnitsky E. Peled, L. Adler-Abramovich, E. Gazit, S. Khatun, P. Stallworth, S. Greenbaum. Effect of peptide nanotube filler on structural and ion-transport properties of solid polymer electrolytes Solid State Ionics 220 (2012) 39–46

3. R. Hadar, D. Golodnitsky, H. Mazor, T. Ripenbein, G. Ardel, Z. Barkay, A. Gladkich,

4. E. Peled. Development and Characterization of Composite YSZ-PEI Electrophoretically Deposited Membrane for Li-Ion Battery, J Phys. Chem. B, 117 (2013) (6), 1577–1584

5. E. Peled, D. Golodnitsky, R. Hadar, H. Mazor, M. Goor and L Burstein, Challenges and Obstacles in the Development of Sodium-Air Batteries, Journal of Power Sources 244 (2013) 771-776

6. M. Alon, A. Blum and E. Peled; Feasibility Study of Hydrogen/Iron Redox Flow Cell for Grid-Storage Applications, JPS, in press (2013)

Research DescriptionThe sodium/air redox couple has the potential to deliver a pronounced step-change in the specific energy of batteries. This is particularly important for electric-vehicle (EV) applications. The main problem of using an alkali-metal anode is the formation of metal dendrites on battery charge. Our research addresses the molten-sodium/air battery. Operating the battery at above the melting point of sodium (97.8oC), in addition to eliminating dendrite formation, could accelerate sluggish cathode reactions and lower cell impedance. Our study was focused on understanding the key parameters that affect the performance of the electrodes and their impact on the operation of the molten-Na/air cell in glymes, PYR14TFSI ionic liquid (IL) and polyethylene oxide-based electrolytes. We have found that the

faradaic efficiency for cycling of molten sodium at 105oC, was lower than 30% in glymes and up to 95% in both ILs and PEO electrolytes containing certain Na-SEI precursors. The electrochemical-stability window (ESW) of IL-based and PEO-based electrolytes varies from 4 to 5.5V. The OCV of the Na/air cell is about 2.2V, and thus fits within the ESW. The performance of the Na/O2 battery with carbon electrodes and with cobalt-nickel oxide ORR catalyst was evaluated. The ionic conductivity of IL-based electrolytes is much higher than that of PEG-based electrolytes.Since the most of oil produced is used for automobile and light trucks, the transition to electric vehicles (EVs) should be a societal goal of a paramount importance. Fuel cells and battery-powered vehicles aimed at a mass-market application must compete with vehicles powered by the internal-combustion engine with respect to cost, driving range, comfort, safety and performance as well as reliability. PEM fuel cells were able to achieve a 500 km driving range for full EVs. High fuel cell cost, and hydrogen filling stations are the obstacles that must be overcome in order to enable commercialization of the fuel cells powered EVs. The most expensive components of the PEM fuel cells are the platinum based cathode and anode catalysts. They contribute more than 40% to the total FC materials cost. In order to meet the cost goal, it is essential to reduce platinum loading by a factor of 5 to 10. We report here on our success in the development of very active oxygen reduction reaction (ORR). By using a core-shell nano-structure concept, we were able, at the same time, to reduce the amount of platinum and to increase the activity of the ORR catalysts.

Page 16: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

14 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Eran Rabani

AFFILIATION: Chemistry

TEL: (972)-3-6407599

EMAIL: [email protected]

WEB: www.tau.ac.il/~rabani

Research TitleTheory and Computationas

Selected Publications:1. M. Grunwald, K. Lutker, A.P. Alivisatos, E. Rabani, P.L. Geissler,

Metastability in Pressure-Induced Structural Transformations of CdSe/ZnS Core/Shell Nanocrystals, Nano Lett. 13, 1367−1372 (2013).

2. P. K. Jain, D. Ghosh, R. Baer, E. Rabani, and A. P. Alivisatos, Near-Field Manipulation of Spectroscopic Selection Rules on the Nanoscale, Proc. Natl. Acad. Sci. USA 109, 8016-8019 (2012).

3. D. Mocatta, G. Cohen, J. Schattner, O. Millo, E. Rabani and U. Banin, Heavily Doped Semiconductor Nanocrystal Quantum Dots, Science 332, 77-81(2011).

4. T. E. Markland, J. A. Morrone, B. J. Berne, K. Miyazaki, E. Rabani and D. R. Reichman, Quantum Fluctuations Can Promote or Inhibit Glass

Formation, Nature Physics 7, 134-137 (2011).5. R. Baer and E. Rabani, Can Impact Excitation

Explain Efficient Carrier Multiplication in Carbon Nanotube Photodiodes?, Nano Lett. 10, 3277-3282 (2010).

Research DescriptionMy work combines theoretical and computational approaches and can be classified to the study of structural and electronic properties and to transport:1) Structural and electronic properties of nanocrystals quantum dotsand how these materials assemble to form ordered arrays with emerging collective behavior. Examples including the development of the first theory for heavily doped semiconductor nanocrystals, the first dynamical model describing how nanoparticles self-assemble and how hetero-structures form at the nanoscale, predicting the formation of multiexciton in nanostructures for solar energy conversion, uncovering the mechanism of pressure induced phase transformation in nanocrystals (physical review letters 2006, nanoletters 2013), and the development of computational tools to simulate nanostructure, including the use of GPUs.2) Transport through molecular junctions. Examples include the study of the Aharonov-Bohm effect and the use of magnetic gating at the nanoscale (JACS communication 2005, physical review letters 2006, accounts of chemical research 2006),the development of real-time path integration approaches to describe the dynamics in strongly correlated open systems and the first numerically exact solution of the Holstein model (physical review letters 2008), and the most recent approach which combines projection techniques with diagrammatic expansions to uncover the behavior of nonequilibrium strongly correlated systems (physical review B). Our recent application of this approach to the Anderson impurity model provides the most accurate and spans the largest range of parameters, even near the nonequilibrium Kondo effect.

Page 17: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

15 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Haim Diamant

AFFILIATION: Chemistry

TEL: (972)-3-6406967

EMAIL: [email protected]

WEB: http://www.tau.ac.il/~hdiamant

Research TitleTheory of complex fluids

Selected Publications:1. Diamant, H., Witten, T. A. (2011). Compression induced folding of a

sheet: An integrable system. Phys Rev Lett 107, 164302.2. Sokolov, Y., Frydel, D., Grier, D. G., Diamant, H., Roichman, Y. (2011).

Hydrodynamic pair attractions between driven colloidal particles. Phys Rev Lett 107, 158302.

3. Diamant, H. (2009). Hydrodynamic interaction in confined geometries. J Phys Soc Jpn 78, 041002.

4. Diamant, H., Agam O. (2010). Localized Rayleigh instability in evaporation fronts. Phys Rev Lett 104, 047801.

5. Oppenheimer N., Diamant H. (2009). Correlated diffusion of membrane proteins and their effect on membrane viscosity. Biophys J 96, 3041-3049.

Research DescriptionOur research group attempts to understand the structure and dynamic response of soft materials and complex fluids using analytical models. Recent projects include instabilities in fluid-supported thin sheets, dynamics of membrane inclusions, correlations in confined suspensions, and the osmotic swelling of vesicles.

Page 18: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

16 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Oded Hod

AFFILIATION: Chemistry

TEL: (972)-3-6405850

EMAIL: [email protected]

WEB: http://www.tau.ac.il/~odedhod/

Research TitleComputational nanomaterials science

Selected Publications:1. I. Leven, D. Krepel, O. Shemesh, and O. Hod, Robust Superlubricity

in Graphene/h-BN Heterojunctions, J. Phys. Chem. Lett. 4, 115-120 (2013).

2. O. Hod, The Registry Index: A Quantitative Measure of Materials Interfacial Commensurability, ChemPhysChem 14, 2376-2391 (2013).

3. A. Blumberg, U. Keshet, I. Zaltsman, and O. Hod, Interlayer Registry to Determine the Sliding Potential of Layered Metal Dichalcogenides: The Case of 2H-MoS2, J. Phys. Chem. Lett. 3, 1936-1940 (2012)

4. J. Garel, I. Leven, C. Zhi, K.S. Nagapriya, R. Popovitz-Biro, D. Golberg, Y. Bando, O. Hod, and Ernesto Joselevich, Ultrahigh Torsional Stiffness and Strength of Boron Nitride Nanotubes, Nano Lett. 12, 6347-6352 (2012).

5. O. Hod, Graphite and Hexagonal Boron-Nitride have the Same Interlayer Distance. Why?, J. Chem. Theory Comput. 8, 1360-1369 (2012).

Research DescriptionNanoscience and nanotechnology open a unique opportunity for the application of highly accurate theories to realistic material science problems. The research in my group focuses on the theoretical study of the mechanical, electronic, magnetic,and transport properties of systems at the nanoscale. Using first-principles computational methods, we aim to characterize both ground

state and dynamical properties of such systems. A combination of codes developed within our group along with commercial computational chemistry packages, operating on a highly parallelizable high-performance computer cluster, allows us to address the properties and functionality of a variety of systems ranging from carefully tailored molecular structures up to bulk systems. On top of basic science questions, the design of technologically applicable nanoscale material properties for future applications in fields such as nano-electronics, nano-spintronics, accurate and sensitive chemical sensing, and nano-mechanical devices, is being pursued.

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RESEARCHERS

17 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Ori Cheshnovsky

AFFILIATION: Chemistry

TEL: (972)-3-6408325)

EMAIL: [email protected]

WEB: http://www2.tau.ac.il/Person/exact/chemistry/researcher.asp?id=abhjlefek

Research TitleMicroscopy and spectroscopy of nano-structures

Selected Publications:1. T. Juffmann, A. Milic, M. Mullneritsch, P. Asenbaum, A. Tsukernik,

J. Tuxen, M. Mayor, O. Cheshnovsky. M. Arndt. (2012). Rea l time single molecule imaging of quantum interference.. Nature Nanotechnology, 7 296-299

2. D. Marchak, D. Glozman, Y. Vinshtein, S. Jarby, Y. Lareah, O. Cheshnovsky and Y. Selzer. (2012) Large anisotropic conductance and band gap fluctuations in nearly round-shape bismuth nanoparticles, Nano Letters,12 pp. 1087-1091.

3. Z. Ioffe,, T. Shamai, A. Ophir, G. Noy, I. Yutsis, K. Kfir, O. Cheshnovsky, Y. Selzer.(2008). Detection of heating in current carrying molecular junctions by Raman scattering,Nature Nanotechnology 3, 727

4. Z. R. Abrams, Z. Ioffe, A. Tsukernik, O. Cheshnovsky, Y. Hanein.(2007) A complete scheme for creating predefined networks of individual carbon nanotubes. Nano Letters 7, 2666-2671 .

5. E. Flaxer, O. Sneh and O. Cheshnovsky. (1993) Molecular light emission induced by inelastic electron tunneling. Science 262, 2012-2014

Research DescriptionRaman Microscopy of nanometric systems: One branch in this research program focuses on developing new methodologies for label-free (Raman) super-resolution microscopy. One methodology aims to merge the enhanced Raman sensitivity of SRS with far field SR approaches. The second methodology is directed towards material science and relies on the temperature dependence of Raman spectroscopy.The other branch in our program aims to further extend our research in Raman spectroscopy characterization of conducting NWs, molecular and other nanometric junctions by introducing ultrafast monitoring of heating and chemical changes.Search of direct band gap Si/Ge nanowires: In 2012 Zunger and coworkers introduced a design for Si/Ge based nanowires (NWs), characterized by mono and bi atomic Ge and Si alternating shells around a Ge core, with remarkable enhancement of absorption at the band edge. Challenged by the importance of Si/Ge-based direct optical gap materials and inspired by the theoretical predictions, we will synthesize and measure the absorption of precisely designed core/multishell Si/Ge NWs. The experimental examination of the concept of these theoretically designed materials will provide an important test case for the property-oriented-design of materials. My group is involved in two other research projects within multi-researcher projects: • Nano materials for optical excitations in cells

(Led by Prof. Yael Hanein TAU). Here we check the ability of nanoparticle CNT interfaces to stimulate neurons.

• Quantum interference of high mass nanoparticles by nanometric gratings(Led by prof. Markus Arndt, Vienna University)

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18 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Yoram Cohen

AFFILIATION: Chemistry

TEL: (972)-3-6407232

EMAIL: [email protected]

WEB: http://www.tau.ac.il/chemistry/cohen/~ycoheng/

Research TitleMRI and constrat agents for imaging of the central nervous systems

Selected Publications:1. Y. Cohen, S. Yariv-Shoushan (2013) Magnetic Nanoparticles-Based

Diagnostics and Theranostics, Curr. Opin. Biotechnology, 32, 672-681.2. I. Zugelboim, A. Weissberg, Y. Cohen, (2013) Target-Specific Ligands

and Gadolinium-Based Complexes for Imaging of Dopamine Receptors: Synthesis, Binding Affinity and Relaxivity, J. Org. Chem., 78, 7001-7012.

3. N. Shemesh, D, Barazany, O. Sadan, L. Bar, N. Sochen, Y. Zur, Y. Barhum,D. Offen, Y. Assaf, Y. Cohen, (2012)Mapping Apparent Eccentricity and Residual Orientation in the Gray Matter Using Angular Double-PFG MRI.Magn. Reson. Med., 68, 794-806.

4. N. Shemesh, C.-F. Westin, Y. Cohen, (21012) Magnetic Resonance Imaging by Synergistic Diffusion Diffraction., Phys. Rev. Letters, 108, 058103 (1-5).

5. N. Shemesh, Y. Cohen, (2011) Probing Microscopic Architecture of Opaque Heterogeneous Systems Using Double-PFG NMR, J. Am. Chem. Soc. 133, 6028-6035.

Research DescriptionMethods for non-invasive imaging of the central nervous systems (CNS) are of prime importance. Such methods should, in principle, increase our ability to early diagnosis different diseases and provide a useful mean for treatment evaluation. Indeed in the last decade magnetic resonance imaging (MRI) became the method of choice for imaging of the CNS. However despite the many advantages of MRI, the method does have two main limitations i.e. relatively low sensitivity and only limited specificity. The mean to partially alleviate these limitations is to develop new, more specific imaging MR methods, and to design target specific contrast agents.In my group we focus on the development of new MRI methods and the design of new CAs for MRI imaging. Our contrast agents are based on paramagnetic complexes and on functional iron-oxide magnetic nanoparticles. We developed magnetic nanoparticles covered by alginates that allow determining changes in extra-cellular calcium levels using conventional MRI. We are preparing CAs for imaging of other biologically important metals. More recently we are involved in the preparation of spiperone-based target specific CAs based on gadolinium complexes and on magnetic nanoparticles (MNps) for non-invasive imaging of the dopamine receptors.

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19 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Roey Amir

AFFILIATION: Chemistry

TEL: (972)-3-640-8435

EMAIL: [email protected]

WEB: http://www.chemistry.tau.ac.il/roeyamir/

Research TitlePEG-dendrimer hybrids

Selected Publications:1. Albertazzi, Lorenzo; Mickler, Frauke M.; Pavan, Giovanni M.; Salomone,

Fabrizio; Bardi, Giuseppe; Panniello, Mariangela; Amir, Elizabeth; Kang, Taegon; Killops, Kato L.; Brauchle, Christoph; Amir, Roey J.; Hawker, Craig J. Enhanced Bioactivity of Internal

2. Amir, Roey J.; Albertazzi, Lorenzo; Williams, Jenny; Kang, Taegon; Khan, Anzar; Hawker, Craig J. Multi-functional Trackable Dendritic Scaffolds and Delivery Agents. Angewandte Chemie, International Edition(2011), 50 (15), 3425-3429.

3. Amir, Roey, J.; Zhong, Sheng; Pochan, Darrin, J.; Hawker, Craig, J. Enzymatically Triggered Self-Assembly of Block Copolymers. Jouranl of the American Chemical Society (2009), 131 (39), 13949-13951.

Research DescriptionDendrimers are very attractive scaffolds for the delivery of therapeutics and/or diagnostic probes, with the two major approaches of loading being: encapsulation and functionalization of the chain ends. While both approaches seem to be promising they suffer from drawbacks due to the limited amount of cargo molecules and control over the stability of the loaded carriers. Therefore, we are looking into the development of novel strategies that provides internal reactive groups that are orthogonal to the moieties at the chain ends using a combination click chemistries. These new hybrid dendritic–linear delivery systems offer significant advantages in terms of loading capacity, stability and biocompatibility.

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20 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Alon Bahabad

AFFILIATION: Electrical Engineering

TEL: (972)-3-6409423

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~alonb/

Research TitleOptical Physics

Selected Publications:1. Alon Bahabad, Margaret M. Murnane and Henry C. Kapteyn,

Manipulating nonlinear optical processes with accelerating light beams, Physical Review A, 84, 033819 (2011).

2. Alon Bahabad, Margaret M. Murnane and Henry C. Kapteyn, Quasi phase matching of momentum and energy for nonlinear optical processes, Nature Photonics, 4, 571-575 (2010).

3. Alon Bahabad, Noa Voloch, Ady Arie, Ariel Bruner and David Eger, Unveiling quasi-periodicity through nonlinear wave mixing in periodic media, Physical Review Letters, 98, Issue 20, 205501 (2007).

4. Alon Bahabad and Ady Arie, Generation of optical vortex beams by nonlinear wave mixing, Optics Express, 15, 17619-17624 (2007).

5. Ron Lifshitz, Ady Arie and Alon Bahabad, Photonic quasicrystals for general purposes nonlinear optical frequency conversion, Physical Review Letters, 95, Issue 13, 133901 (2005).

Research DescriptionWe are interested in theoretical and experimental research in various areas of physical optics. One of our major areas of research is the generation of coherent light sources at very high photon energies (soft X-rays). For this we employ the extreme nonlinear optical process of high-harmonic-generation (HHG). HHG is driven with an intense ultra-short light pulse which ionizes a gaseous medium. The liberated electron is then oscillating in the laser field, gaining kinetic energy. There is a small chance that the electron will encounter the ion from which it was liberated and would recombine with it. The excessive kinetic energy that was gained by the electron is released in the form of a high energy photon. During such a process hundreds of the photons of the laser field can be converted to a single high energy photon. We are interested in mediating this process by employing Plasmon-assisted field enhancement.When the laser light interacts with a metallic nanostructure, electron oscillations on the metal surface can lead to a significant field enhancement. This can be utilized to assist with the process of HHG. In addition, the geometry of the metallic nanostructure can be used to control the beam shape and polarization state of the generated high harmonic radiation.

Page 23: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

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21 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Yossi Lereah

AFFILIATION: Electrical Engineering

TEL: 972-3-6407776

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~lereah/

Research TitleApplication of TEM in quantum mechanics

Selected Publications:1. Noa Voloch-Bloch, Yossi Lereah, Yigal Lilach, Avraham Gover and Ady

Arie, Generation of electron Airy beams, Nature, 494 331-335, 20132. A. Be'er, R. Kofman, F. Phillipp and Y. Lereah, Spontaneous

crystallographic instabilities of Pb nanoparticles in a SiO matrix, Physical Review B76 075410 (2007)

3. Y. Lereah, R. Kofman, J.M. Penisson, G. Deutscher,P. Cheyssac,T. Ben David and A. Bourret, Time Resolved Electron Microscopy Studies of the Structure of Nanoparticles and Their Melting ,Philosophical Magazine (invited paper), 81, 1801 (2001)

4. Y. Lereah, Pattern Formation and Interface Propagation in the Crystallization of Amorphous Alloys, Current Topics in Crystal Growth 7, 59 (2004)Invited paper

5. Y. Lereah, E. Grunbaum and G. Deutscher, Formation of Dense Branching Morphology in the Crystallization of Al:Ge Amorphous Thin Films, Physical Review A 44 8316 (1991)

Research DescriptionRecent progress in fabrication artificial structures at nano meter scale enables to transform the establish knowledge from light optics into electron beams. The transmission electron microscope contains the required optical element. However commercial systems are constructed for microscopy. Accordingly, it is required to modify the operation of the microscope by various methods e.g. using free lens control.

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22 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Jacob Scheuer

AFFILIATION: Electrical Engineering

TEL: (972)-3-6407559

EMAIL: [email protected]

WEB: www.eng.tau.ac.il/~kobys/

Research TitleNano Photonics

Selected Publications:1. J. Scheuer and A. Yariv, Giant Fiber Lasers (GFL): A New Paradigm for

Secure Key Distribution, Phys. Rev. Lett. 97, 140502 (2006).2. J. Scheuer, W. M. J. Green, G. DeRose and A. Yariv, Lasing from a

circular Bragg nanocavity with an ultra-small modal volume, Appl. Phys. Lett. 86, 251101 (2005).

3. Y. Yifat, Z. Iluz, M. Eitan, I. Friedler, Y. Hanein, A. Boag, and J. Scheuer, Quantifying the radiation efficiency of nano antennas, Appl. Phys. Lett. 100, 111113 (2012).

4. J. Scheuer, Ultra-high enhancement of the field concentration in Split Ring Resonators by azimuthally polarized excitation, Opt. Express 19, 25454 (2011).

5. J. Scheuer and A. Yariv, Sagnac Effect in Coupled-Resonator Slow-Light Waveguide Structures, Phys. Rev. Lett. 96, 053901 (2006).

Research DescriptionNano-Photonics deals with the interaction of light and matter in the nano-scale. This research field is of fundamental importance as well as a main route for novel technologies and applications such as sensing, solar energy harvesting, telecommunication and optical computing. Specifically we are focused on the development of nano-antennas for optical frequencies with application to solar energy harvesting, controlled self-assembly and beam shaping; Nano semiconductor lasers for sensing and telecommunications, secure communications using fiber lasers and polymer optics.

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23 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Amir Boag

AFFILIATION: Electrical Engineering

TEL: (972)-3-6408246

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~boag/

Research TitleRectifying nano-antennas

Selected Publications:1. Z. Iluz and A. Boag, Dual-Vivaldi wide band nano-antenna with

high radiation efficiency over the infrared frequency band, Optics Letters, vol. 36, no 15, pp. 2773-2775, (2011).

2. Y. Yifat, Z. Iluz, M. Eitan, I. Friedler, Y. Hanein, A. Boag, and J. Scheuer, Quantifying the radiation efficiency of nano antennas, Applied Physics Letters, vol. 100, 111113, (2012).

3. E. Strassburg, A. Boag, Y. Rosenwaks, Reconstruction of Electrostatic Force Microscopy Images,Review of Scientific Instruments, vol.76, 083705 (5 pages), 28 (2005).

4. A. Boag and B. Z. Steinberg, Narrow Band Micro-Cavity Waveguides in Photonic Crystals, Journal of the Optical Society of America A, vol. 18, no. 11, pp. 2799-2805, (2001).

5. G. Y. Slepyan and A. Boag, Quantum non-reciprocity of nanoscale antenna arrays in timed Dicke states,Physical Review Letters, vol. 111, 023602, (2013).

Research DescriptionThe dramatic increase in worldwide demand for electrical power makes it clear that the development of clean, renewable alternative energy sources is essential, where solar power harvesting is the leading direction. The basic properties of conventional photovoltaic solar cells are determined by the materials' chemistry and corresponding electronic properties. As a result, such solar cells possess inherent and fundamental limitations in terms of optical bandwidth, efficiency and cost. On the other hand, power harvesting utilizing RF approaches has demonstrated high efficiency (exceeding 85%) in the radio-frequency spectral range as well as low fabrication costs. The objective of this research is to develop new detection and power conversion schemes for optical frequencies based on metallic rectifying nano-antennas (rectennas). A nano-rectenna includes two fundamental elements: an antenna and a rectifier. The antenna absorbs the EM power and converts it into electric AC current. The rectifier converts the AC current to DC.We have demonstrated the ability to design, optimize and fabricate ultra-wideband nano antenna arrays and nano-rectifiers. We have measured the spectral properties of the scattered field from these antennas and shown very good agreement with numerical simulations. We have also demonstrated preliminary success in integrating the nano-antennas and the rectifiers. In the framework of this research, we will exploit these abilities to develop a new concept for solar-power harvesting, which can revolutionize the field by providing an inexpensive and efficient approach for direct EM to DC power conversion.

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24 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Gil Rosenman

AFFILIATION: Electrical Engineering

TEL: 972-50-6481638

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~gilr

Research TitleBioinspired nanomaterials: Physics and Applications

Selected Publications:1. A.Handelman, S. Lavrov, A. Kudryavtsev, A. Khatchatouriants, Y.

Rosenberg, E. Mishina, G. Rosenman,Nonlinear Optical Bioinspired Peptide Nanostructures, Advanced Optical Mater. 2013, 1, 875–884

2. N. Amdursky, G. Shalev, A. Handelman, S. Litsyn, A. Natan, Y. Roizin, Y. Rosenwaks, D.Szwarcman and G. Rosenman, Bioorganic Nanodots for Non-Volatile Memory Devices, Appl.Phys.Lett-Materials, 2013,1, 062104-062107

3. B. Bank-Srour, P. Becker, L. Krasovitsky, A. Gladkikh, Y.Rosenberg, Z. Barkay, G. Rosenman, Physical Vapor Deposition of Peptide Nanostructures, Polymer Journal (2013) 45, 494–503

4. N. Amdursky, P. Beker, G. Rosenman,Physics of Peptide Nanostructures and Their Nanotechnology Applications, in thebookPeptide Materials: From Nanostructures to Applications, First Edition. Edited by C. Alemán, A. Bianco and M. Venanzi, John Wiley &

5. A. Handelman, P. Beker, N. Amdursky, G.Rosenman, Physics and Engineering of Peptide Supramolecular Nanostructures, Perspective Review, Phys. Chem. Chem. Phys., 14, 6391–6408, 2012

Research DescriptionThe emerging ‘‘bottom-up’’ nanotechnology reveals a new field of bioinspired nanomaterials composed of chemically synthesized

biomolecules. They are formed from elementary constituents in supramolecular structures by the use of a developed nature self-assembly mechanism. The focus of this work is on intrinsic fundamental physical properties of bioinspired peptide nanostructures and their small building units linked by weak noncovalent bonds. The observed exceptional optical properties indicate a phenomenon of quantum confinement in these supramolecular structures, which originates from nanoscale size of their elementary building blocks. The dimensionality of the confinement gives insight into intrinsic packing of peptide supramolecular nanomaterials. QC regions, revealed in bioinspired nanostructures, were found by us in amyloid fibrils formed from insulin protein. We study ferroelectric and related properties at the nanoscale based on original crystalline asymmetry of the nanoscale building blocks, packing these structures. Among these phenomena we observed nonlinear optical effect of second harmonic generation and piezoelectric effect. In this context, we also revealed a classic solid state physics phenomenon such as reconstructive phase transition observed in bioorganic peptide nanotubes. This irreversible phase transformation leads to drastic reshaping of their quantum structure from quantum dots to quantum wells, which is followed by variation of their space group symmetry from asymmetric to symmetric. We show that the supramolecular origin of these bioinspired nanomaterials provides them a unique chance to be disassembled into elementary building block peptide nanodots of ~2 nm size possessing unique electronic, optical and ferroelectric properties. These multifunctional nanounits could lead to a new future step in nanotechnology and nanoscale advanced devices in the fields of nanophotonics, nanobiomedicine, nanobiopiezotronics, etc.

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25 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Yosi Shacham

AFFILIATION: Electrical Engineering

TEL: (972)-3-640-8064

EMAIL: [email protected]

WEB: eng.tau.ac.il/~yosish

Research TitleInterconnect and interfacing technologiess

Selected Publications:1. Carmit Porat-Ophira,Anton Belkin, Sefi Vernick, Vladimir

Dergachev,Genrietta Freynd, Mikhail Katsnelson and Yosi Shacham-Diamand, Electrochemical Biochip Characterization of the Effect of Formaldehyde on the Activity of Alkaline Phosphatase, ECS Electrochemistry letters, volium 2, issue 12, 68-610, 2013.

2. Nofar Mintz Hemed, Alexandra Inberg, Yosi Shacham-Diamand, On the stability of silicon field effect capacitors with phosphate buffered saline electrolytic gate and self assembled monolayer gate insulator, Electrochimica Acta, 111, 2011.

3. Hadar Ben-Yoav,Alva Biran, Marek Sternheim, Shimshon Belkin, Amihay Freeman, Yosi Shacham-Diamand, Functional modeling of electrochemical whole-cell biosensors , Sensors and Actuators B: Chemical, Volume 181, (2013), Pages 479–485

4. Jenny Shklovsky, Leeya Engel, Yelena Sverdlov, Yosi Shacham-Diamand, Slava Krylov, Nano-imprinting lithography of P (VDF–TrFE–CFE) for flexible freestanding MEMS devices, Microelectronic Engineering (2012).

5. Tetsuya Osaka, Hitoshi Aramaki, Masahiro Yoshino, Kazuyoshi Ueno, Itsuaki Matsuda, and Yosi Shacham-Diamand., Fabrication of Electroless CoWP/NiB Diffusion Barrier Layer on SiO2 for ULSI Devices , JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 156.

Research DescriptionTheory and practice of interconnect and interfacing technology for various applications:- Electrochemical methods; electroless plating- ULSI interconnect technology - MEMS metalization; especially polymer MEMS- Nano-bio interfacing; whole call interfacing

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26 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Abdussalam Azem

AFFILIATION: Life Sciences

TEL: (972)-3-6409007

EMAIL: [email protected]

WEB: http://www.tau.ac.il/lifesci/departments/biochem/members/azem/azem.html

Research Titlemolecular chaperones lab

Selected Publications:1. Iosefson, O., Sharon, S., Goloubinoff, P., Azem, A. Reactivation of

protein aggregates by mortalin and Tid1-the human mitochondrial Hsp70 chaperone system. Cell Stress & Chaperones. 17, 57-66 (2012).

2. Parnas, A., Nisemblat, S., Weiss, C., Levy-Rimler, G., Pri-Or, A., Zor, T., Lund, P., Bross, P., Azem, A. (2012) Identification of Elements that Dictate the Specificity of Mitochondrial Hsp60 for its Co-chaperonin. Plos ONE. 7(12):e50318.

3. Priya, S., Sharma, SK., Sood, V., Mattoo, RU., Finka, A., Azem, A., De Los Rios and Goloubinoff, P. (2013) GroEL and CCT are catalytic unfoldases mediating out-of-cage. Proc. Natl. Acad. Sci. USA.110, 7199-204.

4. Vitlin Gruber, A., Nisemblat, S., Zizelski, G., Parnas, P., Dzikowski, R., Azem, A. and Weiss, W. (2013) P. falciparum cpn20 is a bona fide co-chaperonin that can replace GroES in E. coli. Plos ONE. 8, e53909.

5. Azoulay, I., Kucherenko, N., Nachliel, E., Gutman, M., Azem, A. and Tsfadia, Y. (2013). Tracking the interplay between bound peptide and the Lid domain of DnaK, using Molecular Dynamics. Int. J. Mol. Sci. 14, 12675-12695.

Research DescriptionOur laboratory studies proteins involved in mitochondrial protein import and chaperonin mediated protein folding.Specific projects include 1) Using a structure-function approach to explore the interaction between proteins of the mitochondrial protein import apparatus 2) Analyzing mhsp70 (Mortalin) in vitro to understand how mutations in this protein can cause Parkinson’s disease 3) To investigate chaperonins from the degenerate chloroplast of the malaria parasite and screen for inhibitors 4) Deciphering the structure of organellar chaperonins. 5) Elucidating the pathway of Rubisco folding using chaperonins from A. thaliana.

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27 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Avigdor Eldar

AFFILIATION: Life Sciences

TEL: (972)-3-6407492

EMAIL: [email protected]

WEB: http://www6.tau.ac.il/eldar

Research TitleElucidating bacterial communication systems

Selected Publications:1. Avigdor Eldar, (Social conflict drives the evolutionary divergence of

quorum sensing), Proceedings of the National Academy of Science, 108 (33): 13635-13640 (2011).

2. Partial penetrance facilitates developmental evolution in bacteria. Avigdor Eldar,Vasant K. Chary, Panos Xenopoulos, Michelle E. Fontes,Oliver C. Losón, Jonathan Dworkin, Patrick J. Piggot PJ, Michael B. Elowitz. Nature, 460(7254):510-4 (2009).

3. Self-Enhanced Ligand Degradation Underlies Robustness of Morphogen Gradients Avigdor Eldar, Dalia Rosin, Ben-Zion Shilo and Naama Barkai.Developmental Cell, Vol 5, 635-646 (2003)

4. Robustness of the BMP morphogen gradient in Drosophila embryonic patterning Avigdor Eldar, Ruslan Dorfman, Daniel Weiss, Hilary Ashe, Ben-Zion Shilo and Naama Barkai, Nature 419, 304-308 (2002).

5. Functional Roles for Noise in Genetic Circuits. Avigdor Eldar and Michael Elowitz, Nature, 467(7312):167-173 (2010).

Research DescriptionOur main interest is in understanding the design principles of cooperative behavior in bacteria. More specifically, we focus on how bacterial communication (also known as quorum sensing) is involved in the regulation of cooperation. Our aim is to elucidate the impact of social structure, spatial form and phenotypic hetrogeneity on the development of cooperation and its evolution. We therefore combine tools from microbiology, genetics, molecular biology, microscopy and quantitative modeling to study the phenomenon of cooperation in simple and complex structures. Our main model organisms are the gram-positive soil bacteria B. subtilis and the gram-negative pathogen P. aeruginosa. These two organisms are major model systems of quorum-sensing and biofilm development, allowing us to use their superb genetic tools and vast knowledge base as a starting point for our investigation.

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28 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. David Sprinzak

AFFILIATION: Life Sciences

TEL: (972)-3-6405218

EMAIL: [email protected]

WEB: http://www.tau.ac.il/~davidsp/

Research TitleBiophysics of intercellular signaling

Selected Publications:1. D. Sprinzak, A. Lakhanpal, L. LeBon, L. A. Santat, M. E. Fontes, G. A.

Anderson, J. Garcia-Ojalvo, M. B. Elowitz. Cis interactions between Notch and Delta generate mutually exclusive signaling states, Nature. 6;465(729), (2010).

2. D. Sprinzak and M. Elowitz, Reconstruction of genetic circuits, Nature 438(7067), 443-8 (2005).

3. D. Sprinzak, A. Lakhanpal, L. LeBon, J. Garcia-Ojalvo, M. B. Elowitz.Mutual inactivation of Notch receptors and ligands facilitates developmental patterning, PLoS Comput. Biol. 7(6), (2011).

4. A. Yaron, D. Sprinzak. The cis side of juxtacrine signaling: a new role in the development of the nervous system, Cell press. (2012).

5. O. Shaya, D. Sprinzak, From Notch signaling to fine-grained patterning: Modeling meets experiments. Curr. Opin. Genet. Dev. (2011).

Research DescriptionOur main research goal is to understanding how cells coordinate their differentiation in space and time during embryonic development to form complex patterns of differentiation. To perform these patterning processes cells use extracellular signaling to communicate with their neighbors as well as intracellular genetic circuitry to interpret signaling and make cell fate decisions. We are focusing on developmental patterning processes in which neighboring cells adopt different fates (such as differentiation of neural precursors into neurons and glia). In metazoans, the canonical signaling pathway that coordinates such processes is the Notch signaling pathway. Notch signaling pathway is used for transferring information between neighboring cell: Delta ligands in one cell can interact and activate Notch receptors in a neighboring cell. Notch signaling misregulation often leads to disease states such as cancer and developmental disorders.While we know a lot about the molecular mechanisms of the Notch signaling pathway, we have very little understanding of how the Notch and Delta find each other across the boundary between cells, whether Notch and Delta are evenly distributed or localized in subdomains at the membrane, and how the properties of boundary between the cells affect signaling. To address these questions we develop tools that allow us to measure the dynamic distribution of Notch receptors and Delta ligands on the plasma membrane, to characterize and control the properties of the boundary between cells, and to quantitatively measure the interaction between Notch and Delta across cellular boundaries.

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29 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Iftach Nachman

AFFILIATION: Life Sciences

TEL: (972)-3-6405900

EMAIL: [email protected]

WEB: www.tau.ac.il/~iftachn

Research TitleCell decisions during reprogramming and differentiation

Selected Publications:1. E. Yurkovsky, I. Nachman Event timing at the single cell level. Brief

Funct Genomics 12(2):90-8 doi: 10.1093/bfgp/els057 (2013).2. G. Aidelberg, Y. Goldshmidt, I. NachmanA Microfluidic Device for

Studying Multiple Distinct Strains. J. Vis. Exp., e4257 10.3791/4257, DOI : 10.3791/4257 (2012).

3. Zd. Smith, I. Nachman, A. regev, A. Meissner. dynamic single- cell imaging of direct reprogramming reveals an early specifying event. Nature Biotechnol. 2010 May; 28 (5): 521-6 (2010).

4. I. Nachman, A. regev (2009). BrNI: Integrated modular analysis of transcriptional regulatory programs. BMC Bioinformatics, 10: 155.

5. I. Nachman, A. regev, S. ramanathan. dissecting Timing Variability in yeast Meiosis. Cell 131 (3), 544-556 (2007).

Research DescriptionThe ability of cells to switch their physiological state upon a change in signals is essential to survival of unicellular organisms, development of multicellular ones, disease and response to treatment processes. Such switching decisions are typically studied at the level of cell populations, focusing on the average behavior and often masking extensive variation between individual cells. When such variation occurs in decision processes it can have significant biological implications. For example, it can lead genetically identical cells in the same environment to assume different fates.Our goal is to understand how cells within a population reach developmental decisions at the phenotypic and mechanistic level. How do cells decide to change their state? Why do similar cells respond differently to the same signal? What properties of the cell affect its decision? What determines these properties and their spread in the cell population? What determines which cell states are stable? Our lab will study these fundamental questions in two model systems using methods from live cell fluorescent imaging, statistical and computational analysis.

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30 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Tal Dvir

AFFILIATION: Life Sciences

TEL: (972)-3-6406514

EMAIL: [email protected]

WEB: dvirlab.tau.ac.il

Research TitleTissue Engineering and Regenerative Medicine

Selected Publications:1. Shevach M., Maoz BM., Feiner R., Shapira A.,and Dvir T. Nanoengineering

gold particle composite fibers for cardiac tissue engineering. Journal of Materials Chemistry B. 2013

2. Fleischer S, Feiner R, Shapira S, Ji J, Sui X, Wagner H.D, Dvir T. Spring-like fibers for cardiac tissue engineering. Biomaterials. (2013).

3. Tian B., Liu J., Dvir T. (co-first), Lihua J., Tsui J., Qing Q., Langer R., Kohane D.S., Lieber C.M. Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nature Materials 10.1038/nmat3404 (2012).

4. Dvir T, Timko B.P, Brigham M., Naik Shreesh R., Karajanagi Sandeep S., Parker K.K., Langer R., Kohane D.S. Nanowired 3D cardiac patches. Nature Nanotechnology. 6(11):720-5, (2011).

5. Dvir T. Timko B.P., Kohane D.S. and Langer R. Nanotechnological strategies for engineering complex tissues. Nature Nanotechnology. 6(1):13-22, (2011).

Research DescriptionOur lab develops smart bio and nano technologies for engineering complex tissues. Our work focuses on engineering cardiac patches for treating patients after heart attack, and on development of cyborg tissues integrating micro and nanoelectronics with living organs for controlling their performances.

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31 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Vered Padler-Karavani

AFFILIATION: Life Sciences

TEL: (972)-3-640-9016

EMAIL: [email protected]

WEB: http://nano.tau.ac.il/fta/karavani.html

Research TitleGlycan immune recognition and response in health and in disease

Selected Publications:1. Padler-Karavani V. Aiming at the Sweet Side of Cancer: Aberrant

glycosylation as possible target for personalized-medicine. Cancer Lett. 2013 Oct 16. pii: S0304-3835(13)00732-5. doi: 10.1016/j.canlet.2013.10.005. [Epub ahead of print]. (2013)

2. Kikkeri R, Padler-Karavani V, Diaz S, Verhagen A, Yu H, Hongzhi C, Langereis MA, Groot RdG, Chen X, Varki A. Quantum Dot Nanometal Surface Energy Transfer Based Biosensing Of Sialic Acid Compositions And Linkages In Biological Samples. Anal Chem 85 (2013).

3. Scobie L, Padler-Karavani V, Le Bas-Bernardet S, Crossan C, Blaha J, Matouskova M, Hector R, Cozzi E, Charreau B, Blancho G, Bourdais L, Tallachini M-C, Ribes JM, Kracikova J, Broz L, Hejnar J, Vesely P, Takeuchi Y, Varki A and Soulillou J-P (2013) Lon

4. Padler-Karavani V, Song X, Yu H, Hurtado-Ziola N, Huang S, Muthana S, Chokhawala HA, Cheng J, Verhagen A, Langereis MA, Kleene R, Schachner M, Groot RdG, Lasanajak Y, Schwab R, Chen X, Smith DF, Cummings RD and Varki A. (2012). Cross-Comparison of Protei

5. Padler-Karavani V, Hurtado-Ziola N, Pu M, Yu H, Huang S, Muthana S, Chokhawala H, Cao H, Secrest P, Friedmann-Morvinski D, Singer O, Ghaderi D, Verma IM, Liu Y-T, Messer K, Chen X, Varki A and Schwab R. Human Xeno-Autoantibodies Against a Non-Human (2011).

Research DescriptionOur lab is studying the mechanisms that govern glycan immune recognition and responses in animal models and in humans, both in vitro and in vivo. We combine glycobiology, immunology, biotechnology and cancer research, and use cutting edge technologies within these disciplines, including glycan microarray and glyco-nanotechnology.Current interests include:-Immunological mechanisms of unique anti-carbohydrate antibodies.-Anti-carbohydrate antibodies in mucosal secretions and sera.-Novel diagnostics and therapeutics to chronic inflammation mediated diseases.-Bio-nanotechnology tools based on glycan recognition.

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32 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Alexander Kotlyar

AFFILIATION: Life Sciences

TEL: (972)-3-6407138

EMAIL: [email protected]

WEB: http://www.sashakot.com/

Research TitleApplication of novel DNA-based nanostructures in molecular electronics

Selected Publications:1. Kotlyar A.B.,Borovok N., Molotsky T. , Fadeev L., and Gozin M. (2005).

In Vitro synthesis of uniform Poly(dG)-Poly(dC) by Klenow exo– fragment of Polymerase I. Nucl. Acid Res. 33,525-535.

2. Kotlyar A. B., Borovok N., Molotsky T., Cohen H., Shapir E., and Porath D. (2005). Long, Monomolecular Guanine-Based Nanowires. Adv. Materials 17, 1901-1905.

3. Lubitz I., Zikich D., and Kotlyar A. (2010) Specific High-Affinity Binding of Thiazole Orange to Triplex and G-Quadruplex DNA. Biochemistry 49, 3567-3574.

4. Halamish S.,Eidelshtein G., andKotlyar A. (2013) Plasmon-Coupled Nanostructures Comprising Finite Number of Gold Particles. Plasmonics8, 745-748.

5. Lubitz I., and Kotlyar A. (2011) Self-assembled G4-DNA-silver nanoparticle structures.Bioconjug. Chem.22, 482-487.

Research DescriptionThe main goal of this work is to develop new conductive molecular nanowires based on G4-DNA and complexes of the DNA with photoactive interacaltors and nanoparticles for molecular-optoelectronic devices. We have recently synthesized nanowires composed of single self-folded poly(G) strands of thousands of bases. These G4-wires comprise a large number of stacked guanine tetrads providing better conditions for π overlap compared to base-pairs of the canonical double stranded DNA. A high content of guanines, which have the lowest ionization potential among DNA bases, also makes charge migration through the DNA highly probable. We have shown by electrostatic force microscopy that the quadruplex DNA, in contrast to the double stranded one, exhibit strong signal. These data indicate that the conductivity of G4-DNA is potentially better than that of double stranded DNA, making G4-wires

a valid alternative to dsDNA to develop DNA-based nano-electronics. We have also investigated the interaction of G4-wires with various organic molecules and have demonstrated that incubation of long (hundreds of nanometers) G4-DNA wires with porphyrins and Thiazole orange results in the formation of very stable high affinity intercalative complexes between the DNA and the dyes [5,6]. Binding of Thiazole orange to the wires leads to a tremendous (more than 1000 times) increase in fluorescence of the dye. We have shown that that the mechanism the above dyes binding includes their intercalation between each pair of successive G-tetrad planes in the G4-DNA. The π-stacking between the G-tetrads and the dyes within the G4-DNA-dye complexes might promote conductivity of the wire. In addition the intercalators are pho-electroactive and are capable of abstracting an electron at electrical potentials much lower than the ground state. When complexed with G4-DNA the intercalated molecules will carry the current through the polymer at relatively low applied electrical potentials only in the presence of light. This property is essential for the development molecular electro-optical devices.To achieve the above goals, we collaborate closely with European and Israeli groups specialized in: surface chemistry, nanoelectronics nanooptics, scanning probe microscopy, and electrical transport measurements.

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33 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Itai Benhar

AFFILIATION: Life Sciences

TEL: (972)-3-6407511

EMAIL: [email protected]

WEB: http://www.tau.ac.il/lifesci/departments/biotech/members/benhar/benhar.html

Research TitleTargeted anti fungal nanomedicines

Selected Publications:1. Artzy-Schnirman A, Blat D, Talmon Y, Fishler R, Gertman D, Oren R,

Wolchinsky R, Waks T, Benhar I, Eshhar Z, Sivan U, Reiter Y. (2011) Electrically controlled molecular recognition harnessed to activate a cellular response. Nano Lett. 11(11):4997-5001.

2. Vaks L, Benhar I. (2011) In vivo characteristics of targeted drug-carrying filamentous bacteriophage nanomedicines. J. Nanobiotech 9:58.

3. Saggy I, Wine Y, Shefet-Carasso L, Nahary L, Georgiou G, Benhar I (2012) Antibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining. Protein Engineering, Design & Selection 25(10):539-49

Research DescriptionFor several years we have been developing targeted drug-carrying nanomedicines where the core of the technology are genetically and

chemically engineered virus particles. We developed such guided missiles to treat devastating diseases such as life-threatening infection by drug-resistant bacteria and for potential cancer therapy. Currently we are focusing our efforts to develop such remedies to treat pathogenic fungi that cause life-threatening lung infections in cystic fibrosis and transplantation patients. Usually considered as vicious pathogens, viruses can also be helpful for humans. In particular, viruses that attack bacteria, named bacteriophages can be used for killing bacteria that are resistant to antibiotics and other cells that are bearers of disease. For several years now we have been developing new techniques to genetically modify such viruses to fight specific bacteria or to carry drugs to specific locations in the body in order to treat various diseases, such as cancer and fungal infection.Bacteriophages (phages) are viruses that thrive in bacteria and in many cases kill the host bacteria once finished multiplying themselves. This ability layed ground the classical phage therapy where phages that kill disease-causing bacteria are isolated from natural habitats. Our application, however, is

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34 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

totally different, as we do not rely on the natural ability of the virus to kill its host. Rather, we use is as a long and thin nanoparticles that can be genetically and chemically tailored to fulfill its purpose. Filamentous phages comprise a family of bacterial viruses that have only about 10 genes and grow in well-characterized hosts, the Gram-negative bacteria. Structurally, the filamentous phage is a particle of nanometer dimensions comprising a sheath of several thousand coat proteins in a helical array that during phage maturation, self-assemble around a single-stranded circular DNA molecule at the core. A few minor proteins cap the particle at each end. We group presented a novel technology related to the field of targeted drug delivery in the form of targeted drug-carrying phage nanoparticles. Their approach is based on genetically-modified and chemically manipulated phages. The genetic manipulation endows the phages with the ability to display a host-specificity- conferring ligand (target-specific peptide, recombinant antibody or other target-specifying entity) on their surface. The bacteriophages are chemically conjugated through labile linkages that are subject to controlled cleavage to a drug. The targeted drug carrying phage nanoparticles have a large drug-carrying capacity in excess of ten thousand drug molecules/target site. Previously we are evaluated this approach toward the elimination of pathogenic bacteria and for

cancer therapy. Our current study is focused on developing such phages to treat recalcitrant fungal infections. The antibodies in this case are specific for binding the pathogenic fungus – Aspergillus fumigatus (AF) that causes life-threatening lung infections in immune-compromized patients. We applied antibody phage display to isolate a panel of anti AF antibodies. We have shown that we can form stable complexes between phages that to the anti AF antibodies. In this study, the drug Amphotericin B is to be linked to the phages by means of chemical conjugation through a genetically engineered labile linker subject to controlled release by digested as a result of proteolytic activity of the fungal protease Alp1. We are currently working of drug conjugation of the drug to the phages. During the next year and half we plan to complete the complicated task of conjugating the drug to the phages and to test how efficient is our drug delivery system in killing the fungus in culture and in a mouse lung infection model.

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35 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Judith Rishpon

AFFILIATION: Life Sciences

TEL: (972)-3-6409366

EMAIL: [email protected]

WEB: http://www.tau.ac.il/lifesci/departments/biotech/members/rishpon/rishpon.html

Research TitleBioelectrochemistry and Biosensors

Selected Publications:1. Bareket, L., Rephaeli, A., Berkovitch, G., Nudelman, A. & Rishpon .J.

Carbon nanotubes based electrochemical biosensor for detection of formaldehyde released from a cancer cell line treated with formaldehyde-releasing anticancer prodrugs. Bioelec (2011).

2. Adler-Abramovich, L., Badihi-Mossberg, M., Gazit, E. & Rishpon, J. (2010). Characterization of Peptide-Nanostructure-Modified Electrodes and Their Application for Ultrasensitive Environmental Monitoring Small 6, 825-831.

3. Vernick, S.; Freeman, A.; Rishpon, J.; et al.(2011). Electro-hemical Biosensing for Direct Biopsy Slices Screening for Colorectal Cancer Detection. JOURNAL OF THE ELECTRO-CHEMICAL SOCIETY 1581 P1-P4.

4. Rishpon, Judith; Popovtzer, Rachela; Shacham-Diamand, Yosi; et al. (2012). Electrochemical methods of detecting colon cancer cells and use of same for diagnosing and monitoring treatment of the diseasePatent Number: US 08268577. Patent Assignee: Ramot a

5. Rishpon, J.; Popovtzer, R.; Shacham-Diamand, Y.; et al. (2013) Electrochemical methods of detecting cancer with 4-aminophenyl phosphate. Patent Number: US 08530179.

Research DescriptionOur research is centered on the fundamentals of biological interactions at solid-liquid interfaces with emphasis on electrochemical biosensors. Sensors for medical diagnostics, environmental pollution, food safety, veterinary were developed.Modification of nanoparticles, such as, carbon nanotubes, gold nanotubes, or peptide nanoparticles significantly increases the sensitivity of the sensors and enables measurements of extremely low concentrations.

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36 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Rimona Margalit

AFFILIATION: Life Sciences

TEL: (972)-3-6409822

EMAIL: [email protected]

WEB: none

Research TitleTheranostics of cancer, infections and inflammation by targeted drug carriers

Selected Publications:1. RivkinI, Cohen K, Koffler J, Melikhov D, Peer D, Margalit R. (2010)

Paclitaxel-clusters coated with hyaluronan as selective tumor-targetednanovectors. Biomaterials, 31, 7106-7114

2. MargalitR. (2012) Biomaterial-Based Particulate Drug Carriers. In Handbook of Harnessing Biomaterials in Nanomedicine. Peer D. Ed. Pan Stanford Publishing Pte. Ltd. Singapore. Chapter 1, pp. 1-16

3. Glucksam-Galnoy Y, Tsaffrir Z, Margalit R (2012) Hyaluronan-modified and regular multilamellar liposomes provide sub-cellular targeting to macrophages, without eliciting a pro-inflammatory response. J Cont. Rel. 160, 388–393

4. MargalitR, Yerushalmi N, Peer D,Rivkin I (2012) Formulations of water insoluble or poorly water soluble drugs in lipidated glycosaminoglycan particles and their use for diagnostic and therapy. US patents 8,178,129,

5. MargalitR, Yerushalmi N, Peer D,Rivkin I (2013) Formulations of water insoluble or poorly water soluble drugs in lipidated glycosaminoglycan particles and their use for diagnostic and therapy. US patents 8,501,237

Research DescriptionOur group applies three in house invented and developed lipid-based particulate drug carriers for theranostics of major pathology classes. Three projects are currently running in the lab. Each project includes three stages: (i) Formulation studies – making the drug-carrier systems and characterizing them by structural and physicochemical studies (ii) In vitro studies in cultures of the relevant target and control cell lines, pursuing safety and retention of therapeutic activity of the carrier-encapsulated drug and (iii) In vivo studies in appropriate animal models, pursuing safety and efficacy. Current projects are: (1) Inhalational treatment of respiratory damage by aerosols of hyaluronan-liposomes encapsulating anti-inflammatory and anti-oxidant drugs, a single drug or both in the same liposome. We are currently in the in vivo stage, evaluating safety and efficacy in a mouse model of acute lung inflammation. (2) Theranostics ofheart inflammation (post myocardial infarction) by macrophage-targeted liposomes encapsulating iron nanoparticles, iron complexes, or steroids. We are currently in the in vitro and in vivo stages, in collaboration with Prof. J. Leor from the Faculty of Medicine, TAU. (3) Cancer theranostics, directed at both the cancer cells and the tumor-associated macrophages, by hyaluronan- liposomes encapsulatingiron complexes. We are currently in the in vitro and in vivo stages, in collaboration with Prof. J. Leor from the Faculty of Medicine, TAU.

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37 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Oswaldo Dieguez

AFFILIATION: Materials Science and Engineering

TEL: (972)-3-6409438

EMAIL: [email protected]

WEB: http://departments.icmab.es/leem/dieguez/

Research TitleComputational materials modelling using quantum mechanics

Selected Publications:1. Domain walls in a perovskite oxide with two primary structural

order parameters: first-principles study of BiFeO3; Oswaldo Diéguez, Pablo Aguado-Puente, Javier Junquera, and Jorge Iniguez: PHYSICAL REVIEW B 87, 024102 (2013).

2. First-Principles Investigation of Morphotropic Transitions andPhase-Change Functional Responses in BiFeO3-BiCoO3 Multiferroic SolidSolutions; Diéguez, and Iniguez: PHYSICAL REVIEW LETTERS 107, 057601 (2011).

3. First-principles predictions of low-energy phases of multiferroic BiFeO3; Diéguez, Gonzalez-Vazquez, Wojdel, and Iniguez: PHYSICAL REVIEW B 83, 094105 (2011).

4. First-principles characterization of the structure and electronicstructure of alpha-S and Rh-S chalcogenides; Diéguez, and Marzari: PHYSICAL REVIEW B 80, 214115 (2009).

5. The SIESTA method; developments and applicability; Artacho, Anglada, Diéguez, Gale, Garcia, Junquera, Martin, Ordejon, Pruneda, Sanchez-Portal, and Soler: JOURNAL OF PHYSICS-CONDENSED MATTER 20, 064208 (2008)

Research DescriptionAll matter is made of atoms. By building on this basic assumption and using computers to solve the equations that describe the interaction between atoms, I model the behavior of materials. My main lines of research are:(1) Design and study of multifunctional oxides (with emphasis on ferroelectric and multiferroic materials) (2) Application of computational methods to the study of materials in general, and to the study of materials for energy in particular(3) Development of computational methods for materials science

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38 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Ilan Goldfarb

AFFILIATION: Materials Science and Engineering

TEL: 972-3-6407079

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~ilang

Research TitleEpitaxial nano-structures

Selected Publications:1. I. Goldfarb, D. A. A. Ohlberg, J. P. Strachan, M. D. Pickett, J. J. Yang,

G. Medeiros-Ribeiro, R. S. Williams, Band offsets in transition-metal oxide heterostructures, J. Phys. D - Appl. Phys. 46, 295303 (2013).

2. J.K. Tripathi, G. Markovich, I. Goldfarb, Self-Ordered Magnetic α-FeSi2 Nano-Stripes on Si(111), Appl. Phys. Lett. 102, 251604 (2013).

3. G. Cohen-Taguri, O. Sinkevich, M. Levinshtein, A. Ruzin, and I. Goldfarb, Atomic structure and electrical properties of In(Te) nano-contacts on CdZnTe(110) by scanning probe microscopy, Adv. Funct. Mater. 20(2) 215-223 (2010).

4. I. Goldfarb, Step-mediated size-selection and ordering of heteroepitaxial nanocrystals, Nanotechnology 18, 335304 (2007).

5. I. Goldfarb, Effect of strain on the appearance of subcritical nuclei of Ge nanohuts on Si(001), Phys. Rev. Lett. 95, 025501-4 (2005).

Research DescriptionSelf-assembled nano-structures are interesting from the structural-morphological stand point, as well as due to their unusual physical properties.In my laboratory we explore the self-assembled formation and mesoscopic ordering mechanisms of epitaxial nano-island arrays on surfaces, primarily with the aid of time-resolved scanning tunneling microscope (STM), and the way these growth mechanisms affect the resulting physical properties.For example, we have recently found that some metal-silicon compounds which are non-magnetic in their bulk form can exhibit interesting magnetic properties when grown as self-ordered nano-islands, and that these properties can be further tuned by controlling the size and geometry of the nano-island arrays.

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39 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Noam Eliaz

AFFILIATION: Materials Science and Engineering

TEL: (972) 3-6407384

EMAIL: [email protected]

WEB: http://www.eng.tau.ac.il/~neliaz/

Research TitleFrom corrosion in Space to degradation in vivo and functionality of implants

Selected Publications:1. Lakstein, D., Kopelovitch, W., Barkay, Z., Bahaa, M., Hendel, D., and

Eliaz, N. (2009) Enhanced osseointegration of grit-blasted, NaOH-treated and electrochemically hydroxyapatite-coated Ti-6Al-4V implants in rabbits. Acta Biomaterialia 5, 2258-2269.

2. Naor-Pomerantz, A. Eliaz, N., and E. Gileadi. (2011) Electrodeposition of rhenium-tin nanowires. Electrochimica Acta 56, 6361-6370.

3. Hakshur, K. Benhar, I., Bar-Ziv, Y., Halperin, N., Segal, D., and Eliaz, N. (2011) The effect of hyaluronan injections into human knees on the number of bone and cartilage wear particles captured by bio-ferrography. Acta Biomaterialia 7, 848-857.

4. Mandler, D., Eliaz, N., and Metoki, N. (2013) Preparation of organic self-assembled monolayers either chemisorbed or electrochemically prepared on titanium alloy. US provisional patent application 61/827,903, filed May 28.

5. Eliaz, N. (2012) Degradation of Implant Materials, Springer, NY. DOI 10.1007/978-1-4614-3942-4_10.

Research DescriptionIn line with the demands of modern society, the Biomaterials and Corrosion Laboratory at Tel Aviv University is developing and studying advanced materials for a variety of applications, including biomedical, space, and harsh environments. Among the lab's internationally renowned achievements are:1) The development of novel electrochemically-depositedhydroxyapatite and other calcium phosphate coatings for orthopedic and dental implants. While our current generation of coatings is on its way to commercial use by a manufacturer of dental implants, we are working on the next generations which will incorporate biological matter and drugs to reduce infections, increase the osseointegration, and improve mechanical properties. We are also applying self-assembled monolayers on the titanium substrate in order to increase the adhesion strength.2) Electroplating and electroless plating of rhenium-based alloys. These projects are conducted in collaboration with Prof. EliezerGileadi from the TAU School of Chemistry, and are intended mainly for aerospace, aircraft, and catalysis applications. Funded by the US AFOSR and Israel's DoD. Recently, during a sabbatical leave at Northwestern University (as a scholar of TAU-NU International Institute for Nanotechnology and an Eshbach scholar of the McCormick School of Engineering and Applied Science), Prof. Eliaz studied with Prof. David Seidman et al. the structure of such deposits on the atomic scale, by means of atom probe tomography (APT) and aberration corrected transmission electron microscopy.The magnetic isolation of biological matter for diseases diagnosis (such as cancer and osteoarthritis), determination of the efficacy of drug treatment, and monitoring the wear of artificial joints (either in the design stage or during service in vivo). The lab is the only one outside the US to have this capability (by means of Bio-Ferrography).

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40 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Shachar Richter

AFFILIATION: Materials Science and Engineering

TEL: 972-3-6405711

EMAIL: [email protected]

WEB: http://www.tau.ac.il/~richter1/

Research TitleMolecular and bioelectronics; novel bio-nanocomposites

Selected Publications:1. Mentovich, E ; Richter, S Post-complementary metal-oxide-

semiconductor vertical and molecular transistors: A platform for molecular electronics. Appl. Phys. Lett. 033108) 99 (2012).

2. Carmeli, I. ; Itskovsky , M. A.; Kaufmann , Y.; Shaked, Y.; Richter, S. ; Maniv , T.; Cohen, H. Far-field e-beam detection of hybrid cavity-plasmonic modes in gold micro-holes. Phys. Rev. B ( 2012) 85, 041405 (2012).

3. Carmeli, I, Lewin, A,Flekser E,Zhang, Q,Shen, J, Gozin, MRichter, S, andDagan, YTuning the critical temperature of cuprate superconductor films using self-assembled organic layers.Angew. Chem. Int. Ed.51, 1 – 5 (2012).

4. Mentovich. E,Livanov,K, Prusty D.,Sowwan, M,Richter, SDNA-Nanoparticle Assemblies Go Organic: Macroscopic Polymeric Materials with Nano-sized Features . J. Nanobiotech. 10, (2012).

5. Mentovich, E. ; Belgorodsky, B ; Gozin, M ; Richter, S ; Cohen, H. Doped molecules in miniuterized electrical junctions. J.Amer.Chem. Soc,134, 8468 (2012).

Research DescriptionIn our group we adopt a bottom-up approach to develop and explore various properties of nano-materials, self-assembled monolayers and thin films. For this task we start from the molecular level and by means of molecular synthesis we form the desires basic structures. Examples of these include doped-proteins, chiral nanostructures, and plasmonic materials.These compounds can be formed in a self-assembly fashion, thin films, or as a stand-alone materials.Examples of such structures include the self-assembled monolayers of doped proteins, White-emitting coating for white LEDs and biodegradable plastic and hydrogel made from renewable materials. In order to explore the properties of these materials we have developed new types of nano-devices.These include nano-vertical transistors and circuits, solar-cells and light emitting materials. For this task we develop novel nano-lithography techniques using various techniques. Our group includes students, postdocs and engineers coming from various backgrounds including chemistry, physics, biology and engineering.

Page 43: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

41 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Natan T. Shaked

AFFILIATION: Mechanical Engineering

TEL: (972)-3-6407100

EMAIL: [email protected]

WEB: www.eng.tau.ac.il/~omni

Research TitleOptical microscopy, nanoscopy and interferometry

Selected Publications:1. Girshovitz P. and Shaked, N. T. (2014). Doubling the field of view in

off-axis low-coherence interferometric imaging. Nature – Light: Science and Applications (Nature LSA), In Press.

2. Turko, N. A., Peled, A., andShaked, N. T. (2013). Wide-field interferometric phase microscopy with molecular specificity using plasmonic nanoparticles. Journal of Biomedical Optics 18, 111414:1-8.

3. Girshovitz, P., andShaked, N. T. (2013). Compact and portable low-coherence interferometer with off-axis geometry for quantitative phase microscopy and nanoscopy. Optics Express 21, 5701-5714.

4. Shaked, N. T. (2012). Quantitative phase microscopy of biological samples using a portable interferometer. Optics Letters 37, 2016-2019.

5. Shock, I., Barbul, A., Girshovitz, P., Nevo, U., Korenstein, R., and Shaked, N. T.(2012). Optical phase measurements in red blood cells using low-coherence spectroscopy. Journal of Biomedical Optics 17, 101509:1-5.

Research DescriptionWe develop novel optical microscopy and nanoscopy techniques, with empasis on optical interferometric and spectroscopic microscopy, nanoscopy, and nano-sensing systems, which enable accurate and quantitative measurements and visualization of live biological cell structure, organization, and dynamics, without the need to use fluorescent dyes to enhance contrast. With a wise design of the interferometric imaging setups, we have shown that it is possible to track optical thickness changes of less than 0.2 nm in ambient conditions. Based on these new techniques, we have defined new quantitative parameters for predicting the life-cycle stages of the live cell without any external labeling. In addition, we have shown that we can diagnose cancer based on the rigidity profiles of cancer cells measured in a nonintrusive, noncontact way by recording the nanoscale cell thickness fluctuations using interferometry. We also develop unique compact and portable interferometric setups that can turn a regular microscope into a powerful optical thickness profiler, providing high-accuracy, nondestructive, and noncontact measurements of micro- and nano-structures, even during dynamic lithography. In addition, we develop novel plasmonic nanoparticles for adding molecular specificity and spatial nanoscopy and nano-sensing to interferometric imaging (see figure).

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RESEARCHERS

42 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Slava Krylov

AFFILIATION: Mechanical Engineering

TEL: (972)-3-6405930

EMAIL: [email protected]

WEB: www.eng.tau.ac.il/~vadis

Research TitleDesign and modeling of micro and nano systems

Selected Publications:1. L. Engel, J. Shklovsky, D. Schrieber, S. Krylov and Y.Shaham-Diamand,

freestanding Smooth Micron-Scale Polydimethylsiloxane (PDMS) Membranes by Thermal Imprinting, J. Micromech. Microeng. 22, pap. 045003, 2012.

2. L. Medina, R. Gilat, S. Krylov, Symmetry Breaking in an Initially Curved Micro Beam Loaded by a Distributed Electrostatic Force, International Journal of Solids and Structures, 49(13) 1864-1876, DOI: 10.1016/j.ijsolstr.2012.03.040, 2012.

3. J. Shklovsky, L. Engel, Y. Sverdlov, Y. Shacham-Diamand, S. Krylov, Nano-Imprinting Lithography of P(VDF-TrFE-CFE) for Flexible Freestanding MEMS Devices, Microelectronic Engineering, 100, 41-46, DOI: 10.1016/j.mee.2012.07.112, 2012

4. Y. Linzon, B. Ilic, S. Lulinsky, S. Krylov, efficient Parametric Excitation of Silicon-on-Insulator Microcantilever Beams by Fringing Electrostatic Fields, Journal of Applied Physics, 113, pap. 163508, DOI: 10.1063/1.4802680, 2013.

5. Y. Gerson, I. Sokolov, T. Nachmias, B. R. Ilic, S. Lulinsky, S. Krylov, Pull-in Experiments on Electrostatically Actuated Microfabricated Meso Scale Beams, Sensors and Actuators A, 199, 227-235, DOI: 10.1016/j.sna.2013.05.013, 2013.

Research DescriptionMicro- and nano-electromechanical systems (MEMS/NEMS) • Micro and Nano Electro mechanical systems engineering,

o New concepts in inertial sensors (accelerometers and gyros) through implementation of advanced dynamic phenomena; i.e. nonlinear parametric resonances and parametric amplification, bistability and multistability ,

o New functional materials for polymeric (passive and electro active) MEMS/NEMS,

o Tilting actuators, compliant motion amplifiers, large displacement bistable electrostatic and electro thermal actuators and force/acceleration sensors based on stability monitoring or incorporating

suspended carbon nanotubes (CNT’s),• Dynamics and stability of microstructures, • Micro/nano sensors and actuators,

o Carbon nano-tube based sensors and actuators,

o Resonant gas/biochemical and mass sensors,• Modeling and characterization of MEMS and

NEMS,o Modeling capabilities allowing for mechanical,

electrical and electromechanical simulation of complex polymeric structures including non-linear transport and structural mechanics and integration with the ambient, like swelling and mass transport of ions inside the electroactive gel structure,

o MEMS/NEMS based characterization.

Page 45: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

43 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Yair Shokef

AFFILIATION: Mechanical Engineering

TEL: (972)-3-640-8393

EMAIL: [email protected]

WEB: shokef.tau.ac.il

Research TitleNon-Equilibrium Statistical Mechanics of Soft Mater

Selected Publications:1. Y. Shokef, Y. Han, A. Souslov, A.G. Yodh, and T.C. Lubensky, Buckled

colloidal monolayers connect geometric frustration in soft and hard matter, Soft Matter 9, 6565 (2013)

2. E. Teomy and Y. Shokef, Jamming transition of kinetically-constrained models in rectangular systems, Physical Review E 86, 051133 (2012)

3. Y. Shokef and S.A. Safran, Scaling laws for the response of nonlinear elastic media with implications for cell mechanics, Physical Review Letters 108, 178103 (2012)

4. I. Sochnikov, Y. Shokef, A. Shaulov, and Y. Yeshurun, Single-loop like energy oscillations and staircase vortex occupation in superconducting double networks, Physical Review B 84, 024513 (2011)

5. E. Ben-Isaac, Y.K. Park, G. Popescu, F.L.H. Brown, N.S. Gov, and Y. Shokef, Effective temperature of red blood cell membrane fluctuations, Physical Review Letters 106, 238103 (2011)

Research DescriptionCurrent research in the group covers two main directions in the non-equilibrium statistical mechanics of soft matter systems: 1) Stuck Matter: Geometric frustration, jamming, and slow dynamics in granular matter, colloids, foam and glass-forming liquids, and 2) Live Matter: Nonlinear elasticity and active fluctuations in biological systems.

Page 46: The Center for Nanoscience & Nanotechnology · Prof. Diana Golodnitsky 12 Prof. Emanuel Peled 13 Prof. Eran Rabani 14 Prof. Haim Diamant 15 Prof. Oded Hod 16 Prof. Ori Cheshnovsky

RESEARCHERS

44 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Noam Shomron

AFFILIATION: Medicine

TEL: 972-6-6406594

EMAIL: [email protected]

WEB: www.tau.ac.il/~nshomron

Research TitleGenomics of human diseases

Selected Publications:1. Isakov O, Perrone M, Shomron N. Exome sequencing analysis: a guide

to disease variant detection. Methods Mol Biol. 2013;1038:137-58.2. Gilam A, Edry L, Mamluk-Morag E, Bar-Ilan D, Avivi C, Golan D,

Laitman Y, Barshack I, Friedman E, Shomron N. Involvement of IGF-1R regulation by miR-515-5p modifies breast cancer risk among BRCA1 carriers. Breast Cancer Res Treat. 2013 Apr;138(3):753-60.

3. Mor E, Kano S, Colantuoni C, Sawa A, Navon R, Shomron N. MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients. Neurobiol Dis. 2013 Jul;55:1-10.

4. Shomron N. Genetics research: jumping into the deep end of the pool. Genet Res (Camb). 2013 Feb;95(1):1-3.

5. Isakov O, Ronen R, Kovarsky J, Gabay A, Gan I, Modai S, Shomron N. Novel insight into the non-coding repertoire through deep sequencing analysis. NucleicAcids Res. 2012 Jun;40(11):e86.

Research DescriptionThe Shomron research team focuses on the analysis of genomics aimed at understanding human disease. Combining high-throughput methods and bioinformatics, our team’s research explores gene regulators, such as microRNAs, in order to reach a global, systems perspective on the mechanistic roles small RNA play during disease development.Among our projects Identification of a microRNAs that are in the intersection of several oncogenes; Revealing the influence of microRNAs on pharmacogenomics and personalized medicine; Exposing pathogens in human tissues based on deep sequencing of small RNA molecules followed by subtraction and assembly of the genomes.Overall the Shomron team pursues research that aims to deepen our understanding on the development of diseases in order to generate a significant impact through translating ideas into clinical reality.

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RESEARCHERS

45 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Inna Slutsky

AFFILIATION: Medicine

TEL: (972)-3-6406021

EMAIL: [email protected]

WEB: http://www.slutskylab.com/

Research TitleElucidating the mechanisms underlying synaptic dysfunction in Alzheimr's disease

Selected Publications:1. Dolev, I., Fogel, H., Milshtein, H., Berdichevsky, Y., Lipstein, N., Brose,

N., Gazit, N., Slutsky, I. (2013). Spike bursts increase amyloid-beta 40/42 ratio by inducing a presenilin-1 conformational change. Nature Neuroscience, 16: 587-595.

2. Laviv, T., Vertkin, I., Berdichevsky, Y., Riven, I., Fogel, H., Bettler, B., Slesinger, P. A., and Slutsky, I. (2011). Compartmentalization of the GABAB receptor signaling complexes is required for presynaptic inhibition in hippocampal synapses. J Neurosci. 31(35): 12523-12532.

3. Laviv, T., Riven, I., Dolev, I., Vertkin, I., Balana, B., Slesinger, P.A., Slutsky, I. (2010). Basal GABA regulates GABABR conformation and release probability at hippocampal synapses. Neuron, 67: 253-267.

4. Slutsky, I., Abumaria, N., Wu, L.J., Huang, C., Li, B., Zhao, X., Govindarajan, A., Zhao, M.G., Zhuo, M., Tonegawa, S., Liu, G. (2010). Increasing Synaptic Density and Enhancing Memory by Brain Magnesium. Neuron, 65: 165-177.

Research DescriptionAlzheimer’s Disease (AD) presents a paradigmatic instance of disintegrating neuronal circuits. Strong genetic evidence suggests that changes in the concentration and conformation of amyloid-β peptides (Aβ), the proteolytic products of the amyloid precursor protein, induce a variety of synaptic dysfunctions, thought to cause cognitive decline in

AD. However, experience-dependent mechanisms that initiate synaptic dysfunctions in sporadic, the most frequent form of AD, remain unknown. To address this problem, several key questions should be resolved: How do experience and patterns of neuronal activity regulate Aβ molecular composition and synaptic function? What are the primary synaptic changes that initiate hippocampal dysfunction in AD? What are the signaling complexes transducing Aβ changes to synaptic modifications? To target these questions, we developed an integrative approach combining 2photonFLIM-FRET, imaging of synaptic vesicle recycling, electrophysiology, biochemistry and molecular biology. I will present our data on reciprocal relationships between molecular composition of Aβ and synaptic dynamics in the hippocampus. Moreover, I will show our most recent data on identification of the presynaptic receptor that transduce an increase in the extracellular Aβ concentration into synaptic hyperactivity. Based on our work, we hypothesized that reduction in probability and transfer of spike burst at synapses may represent the key feature initiating dysfunction of hippocampal circuits in Alzheimer's disease.

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RESEARCHERS

46 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Dr. Roy Beck

AFFILIATION: Physics

TEL: (972)-3-6408477

EMAIL: [email protected]

WEB: https://www6.tau.ac.il/beck/

Research TitleExperimental biophysiocs

Selected Publications:1. Almagor, L. Avinery, R., Hirsh,J. and Beck, R. (2013). Structural flexibility

of CaV 1.2 and CaV 2.2 proximal linker fragments in solution, Biophysical Journal 104, 2392-2400, DOI: 10.1016/j.bpj.2013.04.034

2. Kornriech, M., Avinery, R.and Beck, R. (2013).Modern X-Ray Scattering Studies of Complex Biological Systems, Current Opinion in Biotechnology 24, 716-723, DOI: 10.1016/j.copbio.2013.01.005

3. Beck, R., Deek, J. and Safinya, C.R. (2012). Structures and interactions in 'bottlebrush' Neurofilaments: the role of charged disordered proteins in forming hydrogel networks, Biochemical Society Transactions 40 (5), 1027-1031, PMID: 22988859

4. Safinya, C. R.; Deek, J.; Beck, R.; Jones, J. B.; Leal, C.; Ewert, K. K.; Li, Y. (2013) Liquid crystal assemblies in biologically inspired systems. Invited article under review at Liquid Crystals.

5. Beck, R. Deek, J., Jones,J.B. and Safinya,J.B. (2010) Gel Expanded to Gel Condensed Transition in Neurofilament Networks revealed by Direct Force Measurements, Nature Materials 9, 40-46 ,PMID:19915555

Research DescriptionIn many significant biological functions the four basic building blocks (proteins, lipids, sugars and nucleic acids) aggregate to form supramolecular structures and assemblies. The forces and interactions responsible for these assemblies are composed of a set of interactions with energy scales from the order of thermal fluctuation (few KT) to specific covalent bonds on the order of 100's KT. Moreover, relevant length scales in biological systems span over many orders of magnitude, from the single amino acid through polypeptide chains, protein complexes, organelles and up cells and organs. These different length scales present an enormous challenge both experimentally and theoretically.Therefore, in order to properly study biological systems and the interactions within them, it is important to have complementary techniques covering different length-scales and energies, with proximity to their natural environment. In our laboratory we purify the subunit building-blocks using various biochemical and molecular procedures and reassemble them in various conditions to study their supramolecular forces, dynamics and steady-state structures as appear in healthy and diseased states.We use small and wide angle x-ray scattering (WAXS & SAXS) technique to cover length scales from 0.1-100 nm. These techniques are suitable to measure weak scattering from biological system in their natural environment. Detailed analysis and advanced computational techniques are regularly used to convert the reciprocal space to real-space structures and enable studies on the nature of the interactions within the biological assemblies. SAXS, in particular, provides a ready means of determining inter-filament spacing and interactions.Recent advances in solid-state type x-ray detectors and the high flux microfocous x-ray sources allow investigation of dynamic structural events and highly penetrated measurments. Conveniently, these approaches do not require staining or other modifications, and thus do not perturb our system, allowing more ready access to the supramolecular forces underlying self-assembly and simplifying data analysis.

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47 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Eli Eisenberg

AFFILIATION: Physics

TEL: (972)-3-6407723

EMAIL: [email protected]

WEB: www.tau.ac.il/~elieis

Research TitleBioinformatics, RNA editing, Statistical Mechanics

Selected Publications:1. Z. Rotman and E. Eisenberg, Direct Measurements of the Dynamical

Correlation Length Indicate its Divergence at an Athermal Glass Transition, Phys. Rev. Lett., 105, 225503 (2010).

2. Z. Rotman and E. Eisenberg, Finite-temperature liquid-quasicrystal transition in a lattice model, Phys. Rev. E83, 011123 (2011).

3. S. Alon, F. Vigneault, S. Eminaga, D.C. Christodoulou, J.G. Seidman, G.M. Church and E. Eisenberg, Barcoding bias in high-throughput multiplex sequencing of miRNA

4. Genome Research, 21 1506-1511 (2011).5. S. Alon, E. Mor, F. Vigneault, G. Church, F. Locatelli, F. Galeano, A.

Gallo, N. Shomron and E. Eisenberg, Systematic identification of edited microRNAs in the human brain, Genome Research, 22, 1533-1540 (2012)

6. L. Bazak, A. Haviv, M. Barak, J. Jacob-Hirsch, P. Deng, R. Zhang, F.J. Isaacs, G. Rechavi, J.B. Li, E. Eisenberg and E.Y. Levanon, A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes, Genome Research, In press.

Research DescriptionStatistical Mechanics out of Equilibrium: We study simple lattice models in order to elucidate super-cooled fluids, glass transition and crystallization. Recently, we are also interested in understanding the low-T behavior of the phasonic degrees of freedom in quasicrystals.Bioinformatics: We develop novel methods to analyse deep-sequencing RNA data. In particular, this is applied to characterization of RNA editing, and to elucidating circadian gene expression.

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48 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Yoram Dagan

AFFILIATION: Physics

TEL: (972)-3-6405554

EMAIL: [email protected]

WEB: http://physics.tau.ac.il/dagan/index.html

Research TitleStrongly correlated electronic systems

Selected Publications:1. M Ben Shalom, M Sachs, D Rakhmilevitch, A Palevski, Y Dagan, Tuning

Spin-Orbit Coupling and Superconductivity at the SrTiO3/LaAlO3 Interface: A Magnetotransport Study, Physical review letters 104, 126802, 2010

2. M Ben Shalom, CW Tai, Y Lereah, M Sachs, E Levy, D Rakhmilevitch, A Palevski, Y Dagan, Anisotropic magnetotransport at the SrTiO3/LaAlO3 interface, Phys. Rev. B, 80, 140403 (2009)

3. M Ben Shalom, A Ron, A Palevski, Y Dagan, Shubnikov–De Haas Oscillations in SrTiO3/LaAlO3 Interface, Phys. Rev. Lett. 105, 206401, (2010)

4. Y Dagan, R.L. Greene, Hole Superconductivity in electron-doped superconductors Pr 2-xCe_{x}CuO4, Phys. Rev. B. 76, 024506 (2007)

5. E Lahoud, E Maniv, M Shaviv Petrushevsky, M Naamneh, A Ribak, S Wiedmann, L Petaccia, Z Salman, KB Chashka, Y Dagan, A Kanigel, Evolution of the Fermi surface of a doped topological insulator with carrier concentration, Phys. Rev. B, 88, 195107, (2013)

Research DescriptionMaterials in which electrons are strongly interacting with each other exhibit variety of exotic properties such as: high temperature superconductivity, colossal magnetoresistance, ferroelectricity, magneto-electric effects in multiferroic materials. Examples for such materials are: oxide interfaces, cuprates, manganites, nickelates, organic superconductors, dilute magnetic semiconductors, ferroelectrics and many more. Generally speaking, small stimulus results in a large change in one or more physical property. In our laboratory we study the electronic structure and the nature of the phase transitions of such materials by tuning control parameters such as gate voltage, chemical doping, epitaxial strain, external magnetic field etc. One of the advantages of our group is the ability to make materials and study their physical properties in one place. Our laboratory is equipped with a pulsed laser deposition facility controlled by a high pressure RHEED (reflection high energy electron diffraction), advanced and automated low temperature measurements system equipped with He refrigerator and a 14 Tesla magnet. We perform a variety of experiments such as: Magnetotransport, thermal-transport, tunneling and point contact spectroscopy, magnetometry and more. We lean on the fabrication, characterization and electron-microscopy facilities at the Tel Aviv center for nanoscience and nanotechnologies.

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49 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. David J. Bergman

AFFILIATION: Physics

TEL: 972-3-640-8543

EMAIL: [email protected]

WEB: http://www2.tau.ac.il/Person/exact/physics/researcher.asp?id=abddjgchk

Research TitleNano-Plasmonics

Selected Publications:1. Bergman, D. J. ,Perfect Imaging of a Point Charge in the Quasi-Static

Regime, in Physical Review A. (2014).2. D. J. Bergman and Y. M. Strelniker, Exact asymptotics for the strong-

field macroscopic magnetotransport of a composite medium, Phys. Rev. B 82(17), 174422 (2010).

3. R. Magier and D. J. Bergman, Critical point in the strong-field magnetotransport of a three-dimensional binary disordered composite medium, Phys. Rev. B 77, 144406 (6 pp.) (2008).

4. D. J. Bergman and J. S. Ishay, Do Bees and Hornets Use Acoustic Resonance in Order to Monitor and Coordinate Comb Construction? Bulletin of Mathematical Biology 69(5), 1777-1790 (2007).

5. D. J. Bergman and M. I. Stockman, Surface plasmon amplification by stimulated emission of radiation: Quantum generation of coherent surface plasmons in Nanosystems, Phys. Rev. Letters 90, 027402 (4 pp.)(2003).

Research DescriptionI work on the theoretical study of physical properties of composite media.

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50 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Prof. Yael Hanein

AFFILIATION: Electrical Engineering

TEL: (972)-3-6407698

EMAIL: [email protected]

WEB: nano.tau.ac.il/hanein

Research TitleNano Neuro Engineering

Selected Publications:1. Vini Gautam, David Rand, Yael Hanein and K.S. Narayan, A polymer

optoelectronic interface provides visual cues to a blind retina, Advanced Materials, 2013.

2. Moshe David-Pur, Mark Shein, Lilach Bareket, Giora Beit-Ya’akov, Nizan Herzog, Yael Hanein, All-carbon-nanotube flexible neuronal electrodes, Biomed Microdevices, (2013).

3. Mark Shein-Idelson, Eshel Ben-Jacob, and Yael Hanein, Engineered neuronal circuits: A new platform for studying the role of modular topology, Frontiers in Neuroengineering, Vol. 4, 10, (2011).

4. Yuval Yifat, Zeev Iluz, Michal Eitan, Inbal Friedler, Yael Hanein, Amir Boag, and Jacob Scheuer, Quantifying the radiation efficiency of nano antennas, Applied Physics Letters, Vol. 100, pp. 111-113 (2012).

5. Nitzan Herzog, Mark Shein, Yael Hanein, Optical validation of in-vitro extra-cellular neuronal recordings, Journal of Neural Engineering, Vol. 8, pp. 056008, (2011).

Research DescriptionElectronic devices for retinal and brain implant are currently being developed by several research teams. The feasibility to create such devices rests in the ability to produce proper interfacing between the chip and the biological system. Extensive research, conducted over the last several years, demonstrated that Nanotechnology can help making better bio-materials for effective interfacing between nerve cells and electronic chips. Our research activity is concerned with the development of electronic nano devices, in particular, devices designed to interface with brain cells and to record their activity. Using carbon nanotubes (CNT), and CNT-quantum dot (QD) systems we have been able to produce highly effective neuro micro-electrodes suited for high efficacy recording and stimulation.These devices have far reaching applications in the realm of understanding brain disorders, the effect of drugs on the brain and the possibility to build implantable electronic brain chips.

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PUBLICATIONS

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53 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

1. M. Kwiat, R. Elnathan, A. Pevzner, A. Peretz, B. Barak, H. Peretz, T. Ducobni, D. Stein, L. Mittelman, U. Ashery, F. Patolsky, Highly Ordered Large-Scale Neuronal Networks Of Individual Cells – Toward Single Cell To 3D Nanowire Intracellular Interfaces, Acs Appl. Mater. Interfaces, 4 (7), 3542–3549 (2012).

2. D. Azulai, U. Givan, N. Shpaisman, T. Levi Belenkova, H. Gilon, F. Patolsky, And G. Markovich, On-Surface Formation Of Metal Nanowire Transparent Top Electrodes On Cdse Nanowire Array-Based Photoconductive Devices, Acs Appl. Mater. Interfaces, 4 (6), 3157–3162 (2012).

3. Elinav E, Peer D., Harnessing Nanomedicine For Mucosal Theranostics-A Silver Bullet At Last, Acs Nano, 7, 2883-2890. (2013).

4. A. Ben-Simon, H. Eshet, And E. Rabani, On The Phase Behavior Of Binary Mixtures Of Nanoparticles, Acs Nano, 7, 978-986 (2013).

5. O. Hazut, A. Arunava, I. Amit, T. Subramani, S. Zaidiner, Y. Rosenwaks And R. Yerushalmi, Ori Hazut, Arunava Agarwala, Iddo Amit, Thangavel Subramani, Seva Zaidiner, Yossi Rosenwaks, And Roie Yerushalmi, Acs Nano, 6, 10311 (2012).

6. F. Miao, W. Yi, I. Goldfarb, J.J. Yang, M.-X. Zhang, M. D. Pickett, J.P. Strachan, G. Medeiros-Ribeiro, R.S. Williams, Continuous Electrical Tuning Of The Chemical Composition Of Taox-Based Memristors, Acs Nano, 6, 2312-2318 (2012).

7. Joshua B. Edel, Alexei A. Kornyshev, And Michael Urbakh, Self-Assembly Of Nanoparticle Arrays For Use As Mirrors, Sensors, And Antennas, Acs Nanp, 7, 10.1021/Nn405712R (2013).

8. Elinor Josef, Karnit Barat, Iris Barsht, Meital Zilberman And Havazelet Bianco-Peled, ., "Composite Hydrogels As A Vehicle For Drugs With A Wide Range Of Hydrophobicities",, Acta Biomaterialia, Na, Na (2013).

9. Vorup-Jensen T, Peer D., Nanotoxicity And The Importance Of Being Earnest., Adv Drug Deliv Rev., 64, 1661-1662 (2012).

10. Pascal Thébault , Stefan Niedermayer , Stefan Landis , Nicolas Chaix , Patrick Guenoun, Jean Daillant , Xingkun Man,* David Andelman , And Henri Orland, Tailoring Nanostructures Using Copolymer Nanoimprint Lithography, Advanced Materials, 24, 1952-1955 (2012).

11. Hila Toporik , Itai Carmeli , Irina Volotsenko , Michel Molotskii , Yossi Rosenwaks ,Chanoch Carmeli , And Nathan Nelson, Large Photovoltages Generated By Plant Photosystem In Crystals, Advanced Materials, 24, 2988 (2012).

12. Ido M. Herzog, Keith D. Green, Yifat Berkov-Zrihen, Mark Feldman, Roee R. Vidavski, Anat Eldar-Boock, Ronit Satchi-Fainaro, Avigdor Eldar, Sylvie Garneau-Tsodikova, Micha Fridman, 6"-Thioether Tobramycin Analogues: Towards Selective Targeting Of Bacterial Membranes, Angew Chem Int Ed Engl, 51(23), 5652-5656 (2012).

13. Kim, S., Gottfried, A., Lin, R.R., Dertinger, T., Kim, A.S., Chung, S., Colyer, R.A., Weinhold, E., Weiss, S., Ebenstein, Y., Enzymatically Incorporated Genomic Tags For Optical Mapping Of Dna Binding Proteins, Angewandte Chemie, 51, 3578-3581 (2012).

14. Itai Carmeli, Avraham Lewin, Erez Flekser, Itay Diamant, Qiang Zhang, Prof. Jingshan Shen, Dr. Michael Gozin, Dr. Shachar Richter,Prof. Yoram Dagan, Tuning The Critical Temperature Of Cuprate Superconductor Films With Self-Assembled Organic Layers, Angewandte Chemie International Edion, 51, 7162 (2012).

15. Assaf Ben-Moshe, Alexander O. Govorov, Gil Markovich, Enantioselective Synthesis Of Intrinsically Chiral Mercury Sulfide Nanocrystals, Angewandte Chemie International Edition, 52, 1275-1279 (2012).

16. A. Agarwala, T. Subramani, A. Goldbourt, D. Danovich, R. Yerushalmi, Facile Monolayer Formation On Sio2 Surfaces Via Organoboron Functionalities, Angrewandte Chemie International Edition, 52, 7415-7418 (2013).

17. Halpern E., Elias G., Kreitinin V. A., Shtrikman H. And Rosenwaks Y, Direct Measurement Of Surface States Density And Energy Distribution In Individual Inas Nanowires, Apl, None, None (2013).

18. Mentovich, E. ; Richter, S., Post-Complementary Metal-Oxide-Semiconductor Vertical And Molecular Transistors: A Platform For Molecular Electronics., Appl. Phys. Lett, 99, 33108 (2012).

Publications

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PUBLICATIONS

19. I. Goldfarb, F. Miao, J.J. Yang, W. Yi, J.P. Strachan, M.-X. Zhang, M. D. Pickett, G. Medeiros-Ribeiro, R.S. Williams, Electronic Structure And Transport Measurements Of Amorphous Transition-Metal Oxides: Observation Of Fermi Glass Behavior, Applied Physics A, 107, 41285 (2012).

20. Yuval Berg, Sharone Golrding, Shaul Pearl And Ady Arie, Q-Switching An All Fiber Laser Using Acousto-Optic Null Coupler, Applied Physics B, 111, 425-428 (2013).

21. Roy Shiloh And Ady Arie, Poling Pattern For Efficient Frequency Doubling Of Gaussian Beams, Applied Physics B, 109, 573-579 (2012).

22. Y. Yifat, Z. Iluz, M.Eitan, I.Friedler, Y. Hanein, A. Boag, And J. Scheuer, Quantifying The Radiation Efficiency Of Nano Antennas, Applied Physics Letters, 100, 111113 (2012).

23. G. Cohen-Taguri, A. Ruzin, I. Goldfarb, Self-Assembled Formation And Transformation Of In/Cdznte(110) Nano-Rings Into Camel-Humps, Applied Physics Letters, 100, 213116 (2012).

24. A. Ruzin, O. Sinkevich, G. Cohen-Taguri, I. Goldfarb, Anomalous Behavior Of Epitaxial Indium Nano-Contacts On Cadmium-Zinc-Telluride, Applied Physics Letters, 101, 132108 (2012).

25. J.K. Tripathi, G. Markovich, I. Goldfarb, Self-Ordered Magnetic Α-Fesi2 Nano-Stripes On Si(111), Applied Physics Letters, 102, 251604 (2013).

26. E. Halpern, G. Elias, A. V. Kretinin, H. Shtrikman, Y. Rosenwaks, Direct Measurement Of Surface States Density And Energy

Distribution In Individual Inas Nanowires, Applied Physics Letters, 100, 262105-1 (2012).

27. Li Zhang, Robert Hammond, Merav Dolev, Min Liu, Alexander Palevski, And Aharon Kapitulnik, High Quality Ultrathin Bi2Se3 Films On Caf2 And Caf2/Si By Molecular Beam Epitaxy With A Radio Frequency Cracker Cell, Applied Physics Letters, 101, 55226497 (2012).

28. Alex Henning, Gino Günzburger, Res Jöhr, Yossi Rosenwaks, Biljana Bozic-Weber, Catherine E. Housecroft, Edwin C. Constable, Ernst Meyer And Thilo Glatzel, Kelvin Probe Force Microscopy Of Nanocrystalline Tio2 Photoelectrodes, Beilstein Journal Of Nanotechnology, 428, 418 (2013).

29. Bosmat Refaeli, Amir Goldbourt, Protein Expression And Isotopic Enrichment Based On Induction Of The Entner–Doudoroff Pathway In Escherichia Coli, Biochemical And Biophysical Research Communications, 427, 154-158 (2012).

30. R. Beck, J. Deek, C.R. Safinya, Structures And Interactions In 'Bottlebrush' Neurofilaments: The Role Of Charged Disordered Proteins In Forming Hydrogel Networks, Biochemical Society Transactions, 40, 1027-1031 (2012).

31. Natalia Borovok, Elad Gillon, Alexander Kotlyar, Synthesis And Assembly Of Conjugates Bearing Specific Numbers Of Dna Strands Per Gold Nanoparticle, Bioconjugate Chemistry, 23, 916-922 (2012).

32. Lorenzo Albertazzi, Frauke M. Mickler, Giovanni M. Pavan,

Fabrizio Salomone, Giuseppe Bardi, Mariangela Panniello, Elizabeth Amir, Taegon Kang, Kato L. Killops, Christoph Bräuchle, Roey J. Amir And Craig J. Hawker, Enhanced Bioactivity Of Internally Functionalized Cationic

33. Dendrimers With Peg Cores, Biomacromolecules, 13, 4089−4097 (2012).

34. Cohen, S., Coué, G., Beno, D., Korenstein, R., Engbersen, J.F.J., Bioreducible Poly(Amidoamine)S As Carriers For Intracellular Protein Delivery To Intestinal Cells, Biomaterials, 33 (2), Pp. 614-623 (2012).

35. Sharon Fleischer, Ron Feiner, Assaf Shapira, Jing Ji, Xiaomeng Sui, H. Daniel Wagner, Tal Dvir, Spring-Like Fibers For Cardiac Tissue Engineering, Biomaterials, 34, 8599-606 (2013).

36. Miller K, Clementi C, Polyak D, Eldar-Boock A, Benayoun L, Barshack I, Shaked Y, Pasut G And Satchi-Fainaro R, Anti-Angiogenic Activity Of Polyethyleneglycol-Based Paclitaxel And Alendronate For The Treatment Of Breast Cancer Bone Metastases, Biomaterials, 34(15), 3795–3806 (2013).

37. Moshe David-Pur, Mark Shein, Lilach Bareket, Giora Beit-Ya’Akov, Nizan Herzog, Yael Hanein, All-Carbon-Nanotube Flexible Neuronal Electrodes,, Biomed Microdevices, 0, 23974529 (2013).

38. L. Almagor, R. Avineri, J. Hirsh, R. Beck, Structural Flexibility Of Cav 1.2 And Cav 2.2 Proximal Linker Fragments In Solution, Biophysical Journal, 104, 2392-2400 (2013).

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PUBLICATIONS

39. Almagor, L., Avinery, R., Hirsch, J. A., And R. Beck, Structural Flexibility Of Cav1.2 And Cav2.2 I- Ii Proximal Linker Fragments In Solution., Biophysical Journalstructural Flexibility Of Cav1.2 And Cav2.2 I- Ii Proximal Linker Fragments In Solution., 104, 2392 - 2400 (2013).

40. Landesman-Milo D, Goldsmith M, Arie Sl, Witenberg B, Brown E, Leibovitch S, Azriel S, Tabak S, Morad V, Peer D., Hyaluronan Grafted Lipid-Based Nanoparticles As Rnai Carriers For Cancer Cells., Cancer Lett., 334, 221-227. (2013).

41. Emmanuel R., Weinstein S., Landesman-Milo D. And Peer D, Eif3C: A Potential Therapeutic Target For Cancer., Cancer Letters, 336, 158-166 (2013).

42. Rosenblum D. And Peer D, Omics-Based Nanomedicine: The Future Of Personalized Oncology., Cancer Letters, Na, Na (2013).

43. Hilla Fogel, Samuel Frere, Oshik Segev, Shashank Bharill, Ilana Shapira, Neta Gazit, Tiernan O'Malley, Edden Slomowitz, Yevgeny Berdichevsky, Dominic M. Walsh, Ehud Y. Isacoff, Joel A. Hirsch, Inna Slutsky, App Homodimers Transduce Amyloid-Β Mediated Increase In Release Probability At Excitatory Synapses., Cell, Tba, Tba (2013).

44. Assaf Grunwald, Irit Gottfried, Adrienne D. Cox, Yoel Kloog And Uri Ashery, Rasosomes Originate From The Golgi To Dispense Ras Signals, Cell Death And Disease, 4, E496 (2013).

45. Ayal Lavi, Anton Sheinin, Ronit Shapira, Daniel Zelmanoff And Uri Ashery, Doc2B And Munc13-1

Differentially Regulate Neuronal Network Activity, Cerebral Cortex, Na, Doi: 10.1093/Cercor/Bht081 (2013).

46. Y. Michaeli#, T. Shahal#, D. Torchinsky, A. Grunwald, R. Hoch, And Y. Ebenstein, Optical Detection Of Epigenetic Marks: Sensitive Quantification And Direct Imaging Of Individual Hydroxymethylcytosine Bases, Chem. Commun., 49, 8599 - 8601 (2013).

47. Assaf Ben Moshe, Ben M. Maoz, Alexander O. Govorov, Gil Markovich, Chirality And Chiroptical Effects In Inorganic Nanocrystal Systems With Plasmon And Exciton Resonances, Chemical Society Reviews, 42, 7028-7041 (2013).

48. Oded Hod, The Registry Index: A Quantitative Measure Of Materials Interfacial Commensurability, Chemphyschem, 14, 2376-2391 (2013).

49. E. Bormashenko, A. Musina, G. Whymana, Z. Barkay, A. Starostinc, V. Valtsiferc, V. Strelnikovc, Revisiting The Surface Tension Of Liquid Marbles: Measurement Of The Effective Surface Tension Of Liquid Marbles With The Pendant Marble Method, Colloids And Surfaces A: Physicochem. Eng. Aspects, 425, 15-23 (2013).

50. R. Verker, E. Grossman And N. Eliaz, Effect Of The Poss-Polyimide Nanostructure On Its Mechanical And Electrical Properties, Composites Science And Technology, 72, 1408-1415 (2012).

51. M. Levy-Sakin, Y. Ebenstein, Beyond Sequencing: Optical Mapping Of Dna In The Age

Of Nanotechnology And Nanoscopy, Current Opinion In Biotechnology, 24, 41283 (2013).

52. M. Kornriech, R. Avineri, R.Beck, Modern X-Ray Scattering Studies Of Complex Biological Systems, Current Opinion In Biotechnology, 24, 716-723 (2013).

53. Amir Goldbourt, Biomolecular Magic-Angle Spinning Solid-State Nmr: Recent Methods And Applications, Current Opinion In Biotechnology, 24, 705-715 (2013).

54. Sharon Fleischer, Tal Dvir, Tissue Engineering On The Nanoscale: Lessons From The Heart, Current Opinion In Biotechnology, 4, 664-71 (2012).

55. Eldar-Boock A, Polyak D, Scomparin A, Satchi-Fainaro R, Nano-Sized Polymers And Liposomes Designed To Deliver Combination Therapy For Cancer, Current Opinion In Biotechnology, 24, 682–689 (2013).

56. Landesman-Milo D., And Peer D, Toxicity Profiling Of Several Common Rnai-Based Nanomedicines: A Comparative Study., Drug Delivery And Translational Research, Na, Na (2013).

57. Ben-Shushan D, Markovsky E, Gibori H, Tiram G, Scomparin A, Satchi-Fainaro R, Overcoming Obstacles In Microrna Delivery Towards Improved Cancer Therapy, Drug Delivery And Translational Research, In Press, In Press (2013).

58. R. Blanga, D. Golodnitsky, G. Ardel, K. Freedman, A. Gladkich, Yu. Rosenberg, M. Nathan, And E. Peled., Quasi-Solid Polymer-

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PUBLICATIONS

In-Ceramic Membrane For Li-Ion Batteries, Electrochimica Acta, 114, 325-333 (2013).

59. M. Cohen Sagiv, N. Eliaz And E. Gileadi, Incorporation Of Iridium Into Electrodeposited Rhenium-Nickel Alloys, Electrochimica Acta, 88, 240-250 (2013).

60. Gil Shalev, Yossi Rosenwaks, Ilan Levy, The Interplay Between Ph Sensitivity And Label-Free Protein Detection In

61. Immunologically Modified Nano-Scaled Field-Effect Transistor, Elsevier, 31, 510 (2012).

62. O. Shaya, I. Amit, H. Einati, L. Burstein, Y. Shacham-Diamand, Y. Rosenwaks, Molecular Gating Of Transistors By Amine-Terminated Layers, Elsevier, 258, 4069 (2012).

63. Robert Baier, Jascha Lehmann, Sebastian Lehmann, Thorsten Rissom, Christian Alexander Kaufmann, Alex Schwarzmann, Yossi Rosenwaks, Martha Ch.Lux-Steiner, Sascha Sadewasser, Electronic Propertiesofgrainboundariesincu(In,Ga)Se2 Thin Films

64. With Variousga-Contents, Elsevier, 103, 86 (2012).

65. Lilach Bareket And Yael Hanein, Carbon Nanotube Based Micro Electrode Arrays For Neuronal

66. Interfacing: Progress And Prospects, Frontiers In Neural Circuits, 122, 6 (2013).

67. Tuval Ben-Yehezkela, Hadas Zur, Tzipy Marx, Ehud Shapiro, Tamir Tuller, Mapping The Translation Initiation Landscape Of An S. Cerevisiae Gene Using Fluorescent Proteins., Genomics, 13, S0888-7543 (2013).

68. Margalit R., Biomaterial-Based Particulate Drug Carriers, Handbook Of Harnessing Biomaterials In Nanomedicine.

Peer D. Ed. Pan Stanford Publishing Pte. Ltd. Singapore., 1, 41290 (2012).

69. I Sent All The Rest Of The Information Via E-Mail, I Sent All The Rest Of The Information Via E-Mail, I Sent All The Rest Of The Information Via E-Mail, I Sent All The Rest Of The Information Via E-Mail, I Sent All The Rest Of The Information Via E-Mail (I Sent All The Rest Of The Information Via E-Mail).

70. N. Parkansky, A. Vegerhof, E. Faktorovich-Simon, B. Alterkop, O. Berkh, R.L. Boxman, Electrode Material Effect On Submerged Arc Breakdown Of Methylene Blue In Aqueous Solutions, Ijpest, 6, 40913 (2012).

71. Z. Barkay, Dynamic Wettability Study At Nanoscale, Imaging And Microscopy, 15, 51-53 (2013).

72. Peer D., A Daunting Task: Manipulating Leukocyte Function With Rnai., Immunol Rev., 253, 185-197. (2013).

73. Liron Korkidi, Kobi Barkan, And Ron Lifshitz, Analysis Of Dislocations In Quasicrystals Composed Of Self-Assembled Nanoparticles, In Aperiodic Crystals, Eds. Siegbert Schmid, Ray L. Withers, And Ron Lifshitz, Book, 117-124 (2013).

74. Lilach Bareket-Keren And Yael Hanein, Novel Interfaces For Light Directed Neuronal Stimulation:

75. Advances And Challenges, International Journal Of Nanomedicine, 0, 0 (2013).

76. Mizrahy S., Landesman-Milo D., And Peer D., Carbohydrates As Backbones For Glyconanomedicine.Sweet

Fairytale, Israel Journal Of Chemistry, 53, 41288 (2013).

77. Tzahi Cohen Karni, Tal Dvir, Advanced Technologies For Engineering Tissue Mimetic, Israel Journal Of Chemistry, 0, 0 (2013).

78. Evo-Yassaf I, Yaffe Y, Asher M, Ravid O, Eizenberg S, Henis Yi, Nahmias Y, Hirschberg K, Sklan Eh., Ole For Tbc1D20 And Rab1 In Hepatitis C Virus Replication Via Interaction With Lipid Droplet-Bound Nonstructural Protein 5A., J Virol., 86, 6491-502 (2012).

79. Herzog, G., Joerger, A.C., Shmueli, M., Fersht, A.R., Gazit, E. And Segal, D., Evaluating Drosophila P53 As A Model System For Studying Cancer Mutations., J Biol Chem, 287(53, 44330-7 (2012).

80. Shaltiel-Karyo, R., Frenkel-Pinter, M., Matia, N., Patrick, C., Rockenstein, E., Masliah, E., Segal, D., And Gazit, E., A Bbb Disrupter Is Also A Potent Α-Synuclein Aggregation Inhibitor: A Novel Dual Mechanism Of Mannitol For The Treatment Of Parkinson'S Disease., J Biol Chem, 288(24), 17579-88 (2013).

81. Yifat Glucksam-Galnoy Y, Tsaffrir Z, Margalit R, Hyaluronan-Modified And Regular Multilamellar Liposomes Provide Sub-Cellular Targeting To Macrophages, Without Eliciting A Pro-Inflammatory Response, J Cont. Rel, 160, 388–393 (2012).

82. Shlomai A, Rechtman Mm, Burdelova Eo, Zilberberg A, Hoffman S, Solar I,

83. Fishman S, Halpern Z, Sklan Eh., The Metabolic Regulator Pgc-1Α Links Hepatitis C Virus Infection To Hepatic Insulin Resistance., J Hepatol., 57, 867-73 (2012).

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PUBLICATIONS

84. R. Hadar, D. Golodnitsky*, H. Mazor, T. Ripenbein, G. Ardel, Z. Barkay, A. Gladkich,

85. E. Peled. Development And Characterization Of Composite Ysz-Pei Electrophoretically Deposited Membrane For Li-Ion Battery, Development And Characterization Of Composite Ysz-Pei Electrophoretically Deposited Membrane For Li-Ion Battery, J Phys. Chem. B, 117, 1577–1584 (2013).

86. Michael Margaliot, Tamir Tuller, Ribosome Flow Model With Positive Feedback., J R Soc Interface., 10, 20130267 (2013).

87. Guy Aidelberg, Yifat Goldshmidt, Iftach Nachman, A Microfluidic Device For Studying Multiple Distinct Strains, J Vis Exp., 69, Doi:Pii: 4257. 10.3791/4257 (2012).

88. M. Kwiat, R. Elnathan, M. Kwak, J. Willem De Vries, A. Pevzner, Y. Engel, L. Burstein, A. Khatchtourints, A. Lichtenstein, E. Flaxer, A. Herrmann, F. Patolsky, Non-Covalent Monolayer-Piercing Anchoring Of Lipophilic Nucleic Acids: Preparation, Characterization, And Sensing Applications, J. Am. Chem. Soc., 134 (1), 280–292 (2012).

89. A. Segal And A. Gerber, Core Contribution To Magnetotransport Of Ferromagnetic Dots In Vortex State, J. Appl. Phys., 111, 73902 (2012).

90. Alon Hever, Jonathan Bernstein, And Oded Hod, Structural Stability And Electronic Properties Of Sp3 Type Silicon Nanotubes, J. Chem. Phys., 137, 214702 (2012).

91. Tal J. Levy And E. Rabani, Steady State Conductance In A Double Quantum Dot Array: The Nonequilibrium Equation-Of-Motion Green Function Approach, J. Chem. Phys., 138, 164125 (2013).

92. R. Baer And E. Rabani, Biexciton Generation Rates In Cdse Nanorods Are Length Independent, J. Chem. Phys., 138, 51102 (2013).

93. B. Li, T.J. Levy, D.W.H. Swenson, E. Rabani, And W.H. Miller, A Cartesian Quasi-Classical Model To Nonequilibrium Quantum Transport: The Anderson Impurity Model, J. Chem. Phys., 138, 104110 (2013).

94. Mordechai Kornbluth, Tamar Seideman, Abraham Nitzan, Light-Induced Electronic Non-Equilibrium In Plasmonic Particles, J. Chem. Phys., 138, 174707 (2013).

95. Oded Hod, Graphite And Hexagonal Boron-Nitride Have The Same Interlayer Distance. Why?, J. Chem. Theory Comput., 8, 1360-1369 (2012).

96. D. Neuhauser, E. Rabani, And R. Baer, Expeditious Stochastic Approach For Mp2 Energies In Large Electronic Systems, J. Chem. Theory Comput., 9, 24-27 (2013).

97. Goñi-De-Cerio F., Mariani V., Cohen D., Et Al.,, Biocompatibility Study Of Two Di-Block Co-Polymeric Nps For Biomedical Applications By In Vitro Toxicity Testing., J. Nanoparticle Res, 15, 2036 (2013).

98. Scherzer-Attali, R., Convertino, M., Pellarin, R., Gazit , E., Segal, D., And Caflisch, A. ., Methylations Of Tryptophan Modified

Naphtoquinone Affect Its Inhibitory Potential Towards Abeta Aggregation, J. Phys Chem B, 117, 1780-9. (2013).

99. N. Shpaisman, U. Givan., M. Kwiat, A. Pevzner, R. Elnathan, F. Patolsky, Controlled Synthesis Of Ferromagnetic Semiconducting Silicon Nanotubes, J. Phys. Chem. C, 116 (14), 8000–8007 (2012).

100. D. Krepel And O. Hod, Lithium Mediated Benzene Adsorption On Graphene And Graphene Nanoribbons, J. Phys. Chem. C, 117, 19477-19488 (2013).

101. Y. Amit, H. Eshet, A. Faust, A. Patllola, E. Rabani, U. Banin And A. Frenkel, Unraveling The Impurity Location And Binding In Heavily Doped Semiconductor Nanocrystals; The Case Of Cu In Inas Nanocrystals, J. Phys. Chem. C, 117, 13688–13696 (2013).

102. Debora Marchak, Denis Glozman, Yuri Vinshtein, Sigal Jarby, Yossi Lereah, Ori Cheshnovsky, Yoram Selzer, Molecular Control Of Structural Dynamics And Conductance Switching In Bismuth Nanoparticles, J. Phys. Chem. C, 117, 22218-22223 (2013).

103. D. Krepel And O. Hod, Lithium Mediated Benzene Adsorption On Graphene And Graphene Nanoribbons, J. Phys. Chem. C., 117, 19477-19488 (2013).

104. Alon Hever, Jonathan Bernstein, And Oded Hod, Fluorination Effects On The Structural Stability And Electronic Properties Of Sp3 Type Silicon Nanotubes, J. Phys. Chem. C., 117, 14684-14691 (2013).

105. L. Kalikhman-Razvozov, R. Yusupov, And O. Hod, Effects Of Partial Hydrogenation On

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PUBLICATIONS

The Structure And Electronic Properties Of Boron Nitride Nanotubes, J. Phys. Chem. C., N/A, N/A (2013).

106. Vadai Michal, Nachman Nirit, Ben-Zion Matan, Pauly Fabian, Cuevas Juan Carlos., Selzer Yoram, Plasmon Induced Conductance Enhancement In Single Molecule Junctions, J. Phys. Chem. Lett, 4, 2811-2816 (2013).

107. I. Leven, D. Krepel, O. Shemesh, And O. Hod, Robust Superlubricity In Graphene/H-Bn Heterojunctions, J. Phys. Chem. Lett., 4, 115-120 (2013).

108. Adi Blumberg, Uri Keshet, Inbal Zaltsman, And Oded Hod, Interlayer Registry To Determine The Sliding Potential Of Layered Metal Dichalcogenides: The Case Of 2H-Mos2, J. Phys. Chem. Lett., 3, 1936-1940 (2012).

109. D. Neuhauser, E. Rabani, And R. Baer, Expeditious Calculation Of Random-Phase Approximation Energies For Thousands Of Electrons In 3 Dimensions, J. Phys. Chem. Lett., 4, 1172–1176 (2013).

110. G. Zohar, R. Baer, And E. Rabani, Multiexciton Generation In Iv-Vi Nanocrystals: The Role Of Carrier Effective Mass, Band Mixing, And Phonon Emission, J. Phys. Chem. Lett., 4, 317-322 (2013).

111. T.J. Levy And E. Rabani, Symmetry Breaking And Restoration Using The Equation-Of-Motion Technique For Nonequilibrium Quantum Impurity Models, J. Phys.: Condens. Matter., 25, 115302 (2013).

112. Michael Galperin, Abraham Nitzan, Cooperative Effects In Inelastic Tunneling, J. Phys.Chem. B,, 317, 4449-4453 (2013).

113. Stern O, Valdau O, Hung Y, Yaffe Y, Harris E, Hoffmann S, Willbold D, Sklan Eh., An N-Terminal Amphipathic Helix In The Dengue Virus Nonstructural Protein 4A Mediates Oligomerization And Is Essential For Replication, J. Virol., 87, 4080-5 (2012).

114. Agostino Migliore, Abraham Nitzan, Irreversibility And Hysteresis In Redox Molecular Conduction Junctions, J.Am.Chem.Soc, 135, 9420-32 (2013).

115. Naama Karton-Lifshin, Lorenzo Albertazzi, Michael Bendikov Phil S. Baran And Doron Shabat, “Donor-Two-Acceptor” Dye Design: A Distinct Gateway To Nir Fluorescence, Jacs, On Line Now, No Volume Number Yet, Asap (2012).

116. Mikhailovsky Y.O, Mettus D.E,Kazakov, A. P., Prudnikov, V. N.,Kalinin, Yu. E., Sitnikov, A. S., Gerber, A, Bartov, D., Granovsky, A. B., Anomalous Hall Effect In (Co41Fe39B20) (X) (Al-O)(100-X) Nanocomposites, Jetp Letters, 97, 473-477 (2013).

117. A. Segal, M. Karpovski, And A. Gerber, Sixteen-State Magnetic Memory Based On The Extraordinary Hall Effect, Jmmm, 324, 1557 (2012).

118. Y. W. Windsor, A. Gerber, I. Ya. Korenblit, And M. Karpovski, Time Dependence Of Magnetization Reversal When Beginning With Pre-Existing Nucleation Sites, Journal Of Applied Physics, 113, 223902 (2013).

119. Moshe Giladi, Reuven Hiller, Joel Hirsch, Daniel Khananshvili, Population Shift Underlies Ca2+-Induced Regulatory Transitions In The Sodium-Calcium Exchanger

(Ncx), Journal Of Biological Chemistry, 288, 23141-23149 (2013).

120. Benny Cohen, Maoz Panker, Eyal Zuckerman, Maytal Foox And Meital Zilberman, "Effect Of Bioactive Fillers On The Structure And Bonding Strength Of Novel Gelatin-Alginate Bioadhesives",, Journal Of Biomaterials Applications., Na, Na (2013).

121. Amir Kraitzer, David Alperstein And Meital Zilberman, Release Mechanisms Of Antiproliferative Drugs From Highly Porous Bioresorbable Structures, Journal Of Biomedical Materials Research – Part A, 101, 1302-1310 (2013).

122. Tiram G, Scomparin A, Ofek P And Satchi-Fainaro R, Interfering Cancer With Polymeric Sirna Nanocarriers, Journal Of Biomedical Nanotechnology, 10, 50-66 (2014).

123. Shock, I., Barbul, A., Girshovitz, P., Nevo, U., Korenstein, R., Shaked, N.T., Optical Phase Nanoscopy In Red Blood Cells Using Low-Coherence Spectroscopy., Journal Of Biomedical Optics, 17, Pp.101509 (2012).

124. Nir A. Turko, Anna Peled, Natan T. Shaked, Wide-Field Interferometric Phase Microscopy With Molecular Specificity Using Plasmonic Nanoparticles, Journal Of Biomedical Optics, 18, 111414 (2013).

125. Ela Markovsky, Hemda Baabur-Cohen, Anat Eldar-Boock, Liora Omer, Galia Tiram, Shiran Ferber, Paula Ofek, Dina Polyak, Anna Scomparin, Ronit Satchi-Fainaro, Administration, Distribution, Metabolism And Elimination Of Polymer Therapeutics, Journal Of

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Controlled Release, 161, 446–460 (2012).

126. Dvash R., Khatchatouriants A, Solmesky Lj, Wibroe Pp., Weil M., Moghimi Sm., And Peer D, Structural Profiling And Biological Performance Of Phospholipid-Hyaluronan Functionalized Single-Walled Carbon Nanotubes., Journal Of Controlled Released., 295-305., 170 (2013).

127. Nurit P Azouz, Takahide Matsui, Mitsunori Fukuda, Ronit Sagi-Eisenberg, Decoding The Regulation Of Mast Cell Exocytosis By Networks Of Rab Gtpases, Journal Of Immunology, 189, 2169-2180 (2012).

128. Evgeny Nimerovsky, Amir Goldbourt, Insights Into The Spin Dynamics Of A Large Anisotropy Spin Subjected To Long-Pulse Irradiation Under A Modified Redor Experiment, Journal Of Magnetic Resonance, 225, 130-141 (2012).

129. Uzi Eliav, Amir Goldbourt, The Combined Effect Of Quadrupolar And Dipolar Interactions On The Excitation And Evolution Of Triple Quantum Coherences In 7Li Solid State Magic Angle Spinning Nmr, Journal Of Magnetic Resonance, 230, 227-235 (2013).

130. Peer D, Giannechi N. And Luo D., Nanoparticles In Biology, Journal Of Materials Chemistry B, Na, Na (2013).

131. Michal Shevach, Ben Maoz, Ron Feiner, Tal Dvir, Nanoengineering Gold Particle Composite Fibers For Cardiac Tissue Engineering, Journal Of Materials Chemistry B, 0, 0 (2013).

132. Marchak Debora, Glozman Denis, Vinshtein Yuri, Jarby Sigal,

Lereah Yossi, Cheshnovsky Ori, Selzer Yoram, Molecular Control Of Structural Dynamics And Conductance Switching In Bismuth Nanoparticles, Journal Of Physical Chemistry C, 117, 22218–22223 (2013).

133. Yoram Selzer, Uri Peskin, Transient Dynamics In Molecular Junctions: Picosecond Resolution From Dc Measurements By A Laser Pulse Pair Sequence Excitation, Journal Of Physical Chemistry C, 117, 22369–22376 (2013).

134. Muriel E. Layani, Assaf Ben Moshe, Maxim Varenik, Oren Regev, Hui Zhang, Alexander O. Govorov, Gil Markovich, Chiroptical Activity In Silver Cholate Nanostructures Induced By The Formation Of Nanoparticle Assemblies, Journal Of Physical Chemistry C, 117, 22240-22244 (2013).

135. I. Goldfarb, D. A. A. Ohlberg, J. P. Strachan, M. D. Pickett, J. J. Yang, G. Medeiros-Ribeiro, R. S. Williams, Band Offsets In Transition-Metal Oxide Heterostructures, Journal Of Physics D - Applied Physics, 46, 295303 (2013).

136. E. Granot, B. Filanovsky, I. Presman, I. Kuras, F. Patolsky, Hydrazine/Air Direct-Liquid Fuel Cell Based On Nanostructured Copper Anodes, Journal Of Power Sources, V 204, 116–121 (2012).

137. E. Peled, D. Golodnitsky, R. Hadar, H. Mazor, M. Goor And L Burstein, Challenges And Obstacles In The Development Of Sodium-Air Batteries, Journal Of Power Sources, 244, 771-776 (2013).

138. Gennady Eidelshtein, S Halamish, I Lubitz, M Anzola, C Giannini, A Kotlyar, Synthesis And Properties Of Conjugates Between Silver

Nanoparticles And Dna-Pna Hybrids, Journal Of Self-Assembly And Molecular Electronics, 1, 69-84 (2013).

139. Gil Porat And Ady Arie, Efficient, Broadband And Robust Frequency Conversion By Fully Nonlinear Adiabatic Three Wave Mixing, Journal Of The Optical Society Of America B, 30, 1342-1351 (2013).

140. Asia Shapira, Irit Juwiler And Ady Arie, Tunable Nonlinear Beam Shaping By A Non-Collinear Interaction, Lasers And Photonics Reviews, 7, L25-L29 (2013).

141. Ofer Isakov, Marie Perrone, Noam Shomron, Exome Sequencing Analysis: A Guide To Disease Variant Detection., Methods Mol Biol., 1038, 137-158 (2013).

142. Z. Barkay, Quantitative Wettability Study At Nanometer Scale Based On Wet-Stem In Esem, Microsc. Microanal., 18, 1134-1135 (2012).

143. Wang X., Peer D., And Petersen B, New Challenges And Opportunities. Molecular And Cellular Therapies, Molecular And Cellular Therapies, Na, Na (2013).

144. Gil Markovich, Magneto-Transport And Magnetization Dynamics In Magnetic Nanoparticle Assemblies, Mrs Bulletin, 38, 939-944 (2013).

145. I. Leven, I. Azuri, L. Kronik, And O. Hod, Inter-Layer Potential For Hexagonal Boron Nitride, N/A, N/A, N/A (2013).

146. A. Pevzner, Y. Engel, R. Elnathan, A. Tsukernik, Z. Barkay, And F. Patolsky, Confinement-Guided Shaping Of Semiconductor Nanowires And Nanoribbons: 'Writing With Nanowires, Nano Lett, 12 (1), 7–12 (2012).

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147. R. Elnathan, M. Kwiat, A. Pevzner, Y. Engel, L. Burstein, A. Khatchtourints, A. Lichtenstein, R. Kantaev, F. Patolsky, Biorecognition Layer Engineering: Overcoming Screening Limitations Of Nanowire-Based Fet Devices, Nano Lett., 12 (10), 5245–5254 (2012).

148. V. Krivitsky, L. Hsiung, A. Lichtenstein, B. Brudnik, R. Kantaev, R. Elnathan, A. Pevzner, A. Khatchtourints, F. Patolsky, Si Nanowires Forest-Based On-Chip Biomolecular Filtering, Separation And Preconcentration Devices: Nanowires Do It All, Nano Lett., 12 (9), 4748–4756 (2012).

149. M. Ben-Ishai, F. Patolsky, From Crystalline Germanium–Silicon Axial Heterostructures To Silicon Nanowire–Nanotubes, Nano Lett., 12 (3), 1121–1128 (2012).

150. J. Garel, I. Leven, C. Zhi, K.S. Nagapriya, R. Popovitz-Biro, D. Golberg, Y. Bando, O. Hod, And Ernesto Joselevich, Ultrahigh Torsional Stiffness And Strength Of Boron Nitride Nanotubes, Nano Lett., 12, 6347-6352 (2012).

151. B. Filanovsky, E. Granot, R. Dirawi, I. Presman, I. Kuras And F. Patolsky, Nanotextured Metal Copper Substrates As Powerful And Long-Lasting Fuel Cell Anodes, Nano Letters, 11(4), 1727-1732. (2011).

152. Debora Marchak, Denis Glozman , Yuri Vinshtein, Sigal, Jarby, Yossi Lareah, Ori Cheshnovsky And Yoram Selzer,, Large Anisotropic Conductance And Band Gap Fluctuations In Nearly Round-Shape Bismuth Nanoparticles, Nano Letters, 12, 1087-1091 (2012).

153. Iddo Amit, Uri Givan, Justin G. Connell, Dennis F. Paul, John S. Hammond, Lincoln J. Lauhon And Yossi Rosenwaks, Spatially Resolved Correlation Of Active And Total Doping Concentrations In Vls Grown Nanowires, Nano Letters, 13, 2598 (2013).

154. Shapira Eyal, Holtzman Amir, Marchak Debora, Selzer Yoram. 2012, 12, 808., Very High Thermopower Of Bi Nanowires With Embedded Point Contacts, Nano Letters, 12, 808-812 (2012).

155. Arielly Rani., Ofarim Ayelet, Selzer Yoram. Nano Lett. 2012, 12, 2968, Accurate Determination Of Plasmonic Fields In Molecular Junctions By Current Rectification At Optical Frequencies, Nano Letters, 11, 2968-2972 (2012).

156. Marchak Debora, Glozman Denis, Vinshtein Yuri, Cheshnovsky Ori, Selzer Yoram, Large Anisotropic Conductance And Band Gap Fluctuations In Nearly-Round Shape Bi Nanoparticles, Nano Letters, 12, 1087.-1091 (2012).

157. Daniel Azulai, Elad Cohen, Gil Markovich, Seed Concentration Control Of Metal Nanowire Diameter, Nano Letters, 12, 5552-5558 (2012).

158. Ben M. Maoz, Yulia Chaikin, Alexander B. Tesler, Omri Bar Elli, Zhiyuan Fan, Alexander O. Govorov, Gil Markovich, Amplification Of Chiroptical Activity Of Chiral Biomolecules By Surface Plasmons, Nano Letters, 13, 1203-1209 (2013).

159. M. Grünwald, K. Lutker, A.P. Alivisatos, E. Rabani, P.L. Geissler, Metastability In Pressure-Induced Structural Transformations Of Cdse/Zns Core/Shell

Nanocrystals, Nanolett., 13, 1367−1372 (2013).

160. Sanjini U. Nanayakkara, Gilad Cohen, Chun-Sheng Jiang, Manuel J. Romero, Klara Maturova, Mowafak Al-Jassim, Jao Van De Lagemaat, Yossi Rosenwaks, Joseph M. Luther, Built-In Potential And Charge Distribution Within Single Heterostructured Nanorods Measured By Scanning Kelvin Probe Microscopy, Nano letters, 13, 1278 (2013).

161. Howard Ka. And Peer D., Providing The Full Picture: A Mandate For Standardizing Nanoparticle-Based Drug Delivery., Nanomedicine (Lond.), 8(7), 1-3. (2013).

162. J.K. Tripathi, M. Garbrecht, W.D. Kaplan, G. Markovich, I. Goldfarb, Effect Of Fe Coverage On The Structure, Morphology, And Magnetic Properties Of Self-Ordered Α-Fesi2 Nanoislands, Nanotechnology, 23, 495603 (2012).

163. G Cohen, E Halpern, S U Nanayakkara, J M Luther, C Held, R Bennewitz, A Boag, Y Rosenwaks, Reconstruction Of Surface Potential From Kelvin Probe Force Microscopy Images, Nanotechnology, 24, 295702 (2013).

164. Holtzman Amir, Shapira Eyal, Selzer Yoram, Bismuth Nanowires With Very Low Thermal Conductivity As Revealed By The 3w Method, Nanotechnology, 23, 495711-495715 (2012).

165. Noa Voloch-Bloch, Yossi Lereah, Yigal Lilach, Avraham Gover And Ady Arie, Generation Of Electron Airy Beams, Nature, 494, 331-335 (2013).

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166. Michaeli, Y., Ebenstein, Y, Channeling Dna For Optical Mapping, Nature Biotechnology, 30, 762–763 (2012).

167. Thomas Juffmann, Adriana Milic, Michael Mullneritsch, Peter Asenbaum, Alexander Tsukernik, Jens Tuxen, Marcel Mayor, Ori Cheshnovsky, Markus Arndt,, Real Time Single Molecule Imaging Of Quantum Interference, Nature Nanotechnology, 7, 296-299 (2012).

168. Michael Urbakh, Towards Macroscale Superlubricity, Nature Nanotechnology, 8, Doi:10.1038/Nnano.2013.244 (2013).

169. Thomas Juffmann, Adriana Milic, Michael Muellneritsch, Peter Asenbaum, Alexander Tsukernik, Jens Tuexen, Marcel Mayor, Ori Cheshnovsky, Markus Arndt,, Real-Time Single-Molecule Imaging Of Quantum Interference, Nature Nanotechnology, 7, 296-299 (2012).

170. Dolev, I., Fogel, H., Milshtein, H., Berdichevsky, Y., Lipstein, N., Brose, N., Gazit, N., Slutsky, I., Spike Bursts Increase Amyloid-Beta 40/42 Ratio By Inducing A Presenilin-1 Conformational Change., Nature Neuroscience, 16, 587-595 (2013).

171. Redy O, Kisin-Finfer E, Shiran Ferber, Satchi-Fainaro R*, And Shabat D, Synthesis And Use Of Qcy7-Derived Modular Probes For Detection And Imaging Of Biologically Relevant Analytes, Nature Protocols, In Press, In Press (2013).

172. Tzofit Kehat, Kerem Goren And Moshe Portnoy, Effects Of Dendritic Interface On Enantioselective Catalysis By

Polymer-Bound Prolines, New J. Chem., 36, 394-401 (2012).

173. G. Cohen, E. Y. Wilner, And E. Rabani, Memory Methods For Nonequilibrium Quantum Impurity Models: Generalized Projected Dynamics For Non-System Observables, New J. Physics, 15, 73018 (2013).

174. Gil Shalev, Guy Landman, Iddo Amit, Yossi Rosenwaks And Ilan Levi, Specific And Label-Free Femtomolar Biomarker Detection With An Electrostatically Formed Nanowire Biosensor, Npg Asia Materials, 5, E41 (2013).

175. S. Levy, V. Lyubin, M. Klebanov, J. Scheuer, And A. Zadok, Stimulated Brillouin Scattering Amplification In Centimeter-Long Directly Written Chalcogenide Waveguides, Optics Communications, 37, 5112 (2012).

176. Asia Shapira, Ana Libster, Yigal Lilach And Ady Arie, Functional Facets For Nonlinear Crystals, Optics Communications, 300, 244-248 (2013).

177. Ben Z. Steinberg, Parametric Plasmonics And Second Harmonic Generation In Particle Chains, Optics Express, 19, 25843-25853 (2011).

178. J. Scheuer And O. Weiss, The Serpentine Optical Waveguide: Engineering The Dispersion Relations And The Stopped Light Points, Optics Express, 19, 11517 (2011).

179. Jacob Scheuer, Ultra-High Enhancement Of The Field Concentration In Split Ring Resonators By Azimuthally Polarized Excitation, Optics Express, 19, 25454 (2011).

180. E. Megidish, A. Halevy, H. S. Eisenberg, A. Ganany-Padowicz, N. Habshoosh And A. Arie, Compact 2D Nonlinear Photonic Crystal Source Of Beamlike Path Entangled Photons, Optics Express, 21, 6689-6696 (2013).

181. Idith Varon, Gil Porat And Ady Arie, Controlling The Disorder Properties Of Quadratic Nonlinear Photonic Crystals, Optics Letters, 36, 3978-3980 (2011).

182. Gil Porat, Ido Dolev, O. Barlev And Ady Arie, Airy Beam Laser, Optics Letters, 36, 4119-4121 (2011).

183. Asia Shapira, Roy Shiloh, Irit Juwiler And Ady Arie, Two-Dimensional Nonlinear Beam Shaping, Optics Letters, 37, 2136-2138 (2012).

184. Roy Shiloh And Ady Arie, Spectral And Temporal Holograms With Nonlinear Optics, Optics Letters, 37, 3591-3593 (2012).

185. Y. Yifat, Z. Iluz, D. Bar-Lev, M. Eitan, Y. Hanein, A Boag, And J. Scheuer, High Load-Sensitivity In Wideband Infrared Dual-Vivaldi Nanoantennas, Optics Letters, 38, 205 (2013).

186. Jeny Karabline, Moshe Portnoy, Solid-Phase Synthesis And Acidolytic Degradation Of Sterically Congested Oligoether Dendrons, Organic & Biomolecular Chemistry, 10, 4788-4794 (2012).

187. Ferdinand Rissner, Amir Natan, David A. Egger, Oliver T. Hofmann, Leeor Kronik And Egbert Zojer, Dimensionality Effects In The Electronic Structure Of Organic Semiconductors Consisting Of Polar Repeat Units, Organic Electronics, 13, 3165-3176 (2012).

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188. Horev-Azaria L., Baldi G., Beno D., Et Al., Predictive Toxicology Of Cobalt Ferrite Nanoparticles: Comparative In-Vitro Study Of Different Cellular Models Using Methods Of Knowledge Discovery From Data, Particle And Fibre Toxicology, 10, 32 (2013).

189. Marinescu M., Urbakh M. And Kornyshev A.A., Voltage-Dependent Capacitance Of Metallic Nanoparticles At A Liquid/Liquid Interface,, Phys. Chem. Chem. Phys, 14, 1371 – 1380 (2012).

190. L. Galperin And A. Nitzan, Molecular Optoelectronics: The Interaction Of Molecular Conduction Junctions With Light, Phys. Chem. Chem. Phys., 14, 9421 - 9438 (2012).

191. Marinescu, M. Urbakh, A. A. Kornyshev, Voltage-Dependent Capacitance Of Metallic Nanoparticles At A Liquid/Liquid Interface, Phys. Chem. Chem. Phys., 14, 1371 – 1380 (2012).

192. A. A. Kornyshev, M. Marinescu, J. Paget, M. Urbakh, Reflection Of Light By Metal Nanoparticles At Electrodes, Phys. Chem. Chem. Phys., 14, 1850-1859 (2012).

193. Kornyshev A.A., Marinescu M., Paget J., And Urbakh M., Reflection Of Light By Metal Nanoparticles At Electrodes, Phys. Chem. Chem. Phys., 14, 1850-1859 (2012).

194. I. Frankel, Gt.Yossifon &T. Miloh, Dipolophoresis Of Dielectric Spheroids Under Asymmetric Fields, Phys. Of Fluids, 24, 12004 (2012).

195. A.Boymelgreen &T. Miloh, Alternating Current Induced Charge Electrophoresis Of Leaky

Dielectric Janus Particles, Phys. Of Fluids, 24, 82003 (2012).

196. K. Oren, M. Galperin And A. Nitzan, Raman Scattering From Molecular Conduction Junctions: The Charge Transfer Mechanism, Phys. Rev., B, 85, 115435 (2012).

197. D. Rai, O. Hod And A. Nitzan, Magnetic Fields Effects On The Electronic Conduction Properties Of Molecular Ring Structures, Phys. Rev., B 85, 155440 (2012).

198. R. Novitski, B. Z. Steinberg, And J. Scheuer, Losses In Rotating Degenerate Cavities And A Coupled-Resonator Optical-Waveguide Rotation Sensor, Phys. Rev. A, 85, 23813 (2012).

199. Roman Novitski, Ben Z. Steinberg, And Jacob Scheuer, Losses In Rotating Degenerate Cavities And A Coupled-Resonator Optical-Waveguide Rotation Sensor, Phys. Rev. A., 85, 023813,1-6 (2012).

200. D. J. Bergman And Y. M. Strelniker, Strong-Field Magneto-Transport In A Two-Constituent Columnar Composite Medium Where The Constituents Have Comparable Resistivity Tensors, Phys. Rev. B, 86, 024414 (14 Pp.) (2012).

201. O. Hod, Interlayer Commensurability And Superlubricity In Rigid Layered Materials, Phys. Rev. B, 86, 75444 (2012).

202. D. Rai, O. Hod, And A. Nitzan, Magnetic Fields Effects On The Electronic Conduction Properties Of Molecular Ring Structures, Phys. Rev. B, 85, 155440 (2012).

203. E. Flekser, M. Ben Shalom, M. Kim, C. Bell, Y. Hikita, H. Y. Hwang And Y. Dagan, Magnetotransport Effects In Polar Versus Non-Polar

Srtio3 Based Heterostructures, Phys. Rev. B, 86, 121104 (2012).

204. M. Petrushevsky, E. Lahoud, A. Ron, E. Maniv, I. Diamant, I. Neder, S. Wiedmann, V.K. Guduru, F. Chiappini, U. Zeitler, J.C. Maan, K. Chashka, A. Kanigel And Y. Dagan, Probing The Surface States In Bi2Se3 By Shubnikov-De Haas Effect, Phys. Rev. B, 86, 45131 (2012).

205. K. Jin, P. Bach, X. H. Zhang, U. Grupel, E. Zohar, I. Diamant, Y. Dagan, S. Smadici, P. Abbamonte, and R. L. Greene, Anomalous enhancement of the superconducting transition temperature of electron-doped La2-xCexCuO4 and Pr2-xCexCuO4 cuprate heterostructures, Phys. Rev. B, 83, 60511 (2011).

206. Yarden Mazor And Ben Z. Steinberg, Longitudinal Chirality, Enhanced Non-Reciprocity, And Nano-Scale Planar One-Way Plasmonic Guiding,, Phys. Rev. B, 86, 045120,1-5 (2012).

207. Oded Hod, Interlayer Commensurability And Superlubricity In Rigid Layered Materials, Phys. Rev. B, 86, 75444 (2012).

208. Dhurba Rai, Oded Hod, And Abraham Nitzan, Magnetic Fields Effects On The Electronic Conduction Properties Of Molecular Ring Structures, Phys. Rev. B, 85, 155440 (2012).

209. E. Y. Wilner, H. Wang, G. Cohen, M. Thoss, And E. Rabani, Bistability In A Quantum System With Electron-Phonon Interactions Under Finite Bias, Phys. Rev. B, 88, 45137 (2013).

210. G. Cohen, E. Gull, D. R. Reichman, A. J. Millis, And E. Rabani,

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Numerically Exact Long Time Magnetization Dynamics At The Nonequilibrium Kondo Crossover Of The Anderson Impurity Model, Phys. Rev. B, 87, 195108 (2013).

211. Ze'Ev Lindenfeld And Ron Lifshitz, Damping Of Mechanical Vibrations By Free Electrons In Metallic Nanoresonators, Phys. Rev. B, 87, 85448 (2013).

212. Carmeli, I.; Itskovsky , M. A.; Kaufmann , Y.; Shaked , Y.; Richter, S. ; Maniv, T.; Cohen, H., Far-Field E-Beam Detection Of Hybrid Cavity-Plasmonic Modes In Gold Micro-Holes., Phys. Rev. B (Rapid Commun)., 85, 41405 (2012).

213. Eyal Kenig, M.C. Cross, L.G. Villanueva, R.B. Karabalin, M.H. Matheny, Ron Lifshitz, And M.L. Roukes, Optimal Operating Points Of Oscillators Using Nonlinear Resonators, Phys. Rev. E, 86, 56207 (2012).

214. E. Kosheleva, B. Leahy, H. Diamant, B. Lin, S. A. Rice, Long-Range Hydrodynamic Correlations In Quasi-One-Dimensional Circular And Straight Geometries, Phys. Rev. E, 86, 41402 (2012).

215. D. Ben-Yaakov, D. Andelman, H. Diamant, Interaction Between Heterogeneously Charged Surfaces: Surface Patches And Charge Modulation, Phys. Rev. E, 87, 22402 (2013).

216. H. Diamant, T. A. Witten, Shape And Symmetry Of A Fluid-Supported Elastic Sheet, Phys. Rev. E, 88, 12401 (2013).

217. N. Oppenheimer, H. Diamant, T. A. Witten, Anomalously Fast Kinetics Of Lipid Monolayer Buckling, Phys. Rev. E, 88, 22405 (2013).

218. Xingkun Man, David Andelman, Henri Orland, Block Copolymer Films With Free Interfaces: Ordering By Nano-Patterned Substrates, Phys. Rev. E (Rapid Communication), 86, 010801.1-5 (2012).

219. Naomi Oppenheimer, Haim Diamant, In-Plane Dynamics Of Membranes With Immobile Inclusions, Phys. Rev. Lett., 107, 258102 (2011).

220. Eyal Kenig, M.C. Cross, L.G. Villanueva, R.B. Karabalin, M.H. Matheny, Ron Lifshitz, And M.L. Roukes, Passive Phase Noise Cancellation Scheme, Phys. Rev. Lett., 108, 264102 (2012).

221. R. Baer, D. Neuhauser, And E. Rabani,, Self-Averaging Stochastic Kohn-Sham Density Functional Theory, Phys. Rev. Lett., 111, 106402 (2013).

222. Eyal Kenig, M.C. Cross, Ron Lifshitz, R.B. Karabalin, L.G. Villanueva, M.H. Matheny, And M.L. Roukes, Passive Phase Noise Cancellation Scheme, Phys. Rev. Lett., 108, 264102 (2012).

223. L.G. Villanueva, E. Kenig, R.B. Karabalin, M.H. Matheny, Ron Lifshitz, M.C. Cross, And M.L. Roukes, Surpassing Fundamental Limits Of Oscillators Using Nonlinear Resonators, Phys. Rev. Lett., 110, 177208 (2013).

224. Jiarui Yang, Ze Liu, Francois Grey, Zhiping Xu, Xide Li, Yilun Liu, Michael Urbakh, Yao Cheng, And Quanshui Zheng, Observation Of High-Speed Microscale Superlubricity In Graphite, Phys. Rev. Lett., 110, 255504 (2013).

225. Barel I., Urbakh M., Jansen L. And Schirmeisen A.,, Unexpected Temperature And Velocity Dependencies Of Atomic-Scale

Stick-Slip Friction, Phys.Rev. B., 84, 115417 (2011).

226. A. E. Filippov, V. L. Popov, M. And Urbakh, Mechanism Of Wear And Ripple Formation Induced By The Mechanical Action Of An Atomic Force Microscope Tip, Phys.Rev. Lett., 106, 25502 (2011).

227. Capozza R., Rubinstein S. M., Barel I., Urbakh M., Fineberg J.,, Stabilizing Stick-Slip Friction, Phys.Rev. Lett., 107, 24301 (2011).

228. Evgeny Nimerovsky, Amir Goldbourt, Distance Measurements Between Boron And Carbon At Natural Abundance Using Magic-Angle Spinning Reapdor Nmr And A Universal Curve, Physical Chemistry Chemical Physics, 14, 13437-13443 (2012).

229. A. Handelman, P. Beker, N. Amdursky, G.Rosenman, Physics And Engineering Of Peptide Supramolecular Nanostructures, Perspective Review, Physical Chemistry Chemical Physics, 14, 6391–6408 (2012).

230. E. Levy, I. Sternfeld, M. Eshkol, M. Karpovski, B. Dwir, A. Rudra, E. Kapon, Y. Oreg, And A. Palevski, Experimental Evidence For Luttinger Liquid Behavior In Sufficiently Long Gaas V-Groove Quantum Wires, Physical Review, 85, 15857009 (2012).

231. Y. Bekenstein, K. Vinokurov, T.J. Levy, E. Rabani, U. Banin, And O. Millo, Periodic Negative Differential Conductance In A Single Metallic Nano-Cage, Physical Review B, 86, 85431 (2012).

232. Daniel Szwarcman, Axel Lubk, Martin Linck, Karin Vogel, Yossi Lereah, Hannes Lichte, Gil Markovich, Ferroelectric Effects

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In Individual Batio3 Nanocrystals Investigated By Electron Holography, Physical Review B, 85, 134112 (2012).

233. Eyal Levy, Itay Sternfeld, Moshe Eshkol, Michael Karpovski, Benjamin Dwir, Alok Rudra, Eli Kapon, Yuval Oreg, And Alexander Palevski, Experimental Evidence For Luttinger Liquid Behavior In Sufficiently Long Gaas V-Groove Quantum Wires, Physical Review B, 85, 45315 (2012).

234. Nicholas P. Breznay, Hanno Volker, Alexander Palevski, Riccardo Mazzarello, Aharon Kapitulnik, And Matthias Wuttig, Weak Antilocalization And Disorder-Enhanced Electron Interactions In Annealed Films Of The Phase-Change Compound Gesb2Te4, Physical Review B, 86, 205302 (2012).

235. Y. W. Windsor, A. Gerber And M. Karpovski, Dynamics Of Successive Minor Hysteresis Loops, Physical Review B, 85, 64409 (2012).

236. E Lahoud, E Maniv, M Petrushevsky, M Naamneh, A Ribak, S Wiedmann, Z. Salman, Y. Dagan And A. Kanigel, Evolution Of The Fermi Surface Of A Doped Topological Insulator With Carrier Concentration, Physical Review B, Accepted, 0 (2013).

237. D Rakhmilevitch, I Neder, Mb Shalom, A Tsukernik, M Karpovski, Y Dagan, A. Palevski, Anomalous Response To Gate Voltage Application In Mesoscopic Laalo3/Srtio3 Devices, Physical Review B, 87, 125409 (2013).

238. E Flekser, Mb Shalom, M Kim, C Bell, Y Hikita, Hy Hwang, Dgan Y, Magnetotransport Effects In Polar

Versus Non-Polar Srtio_ {3} Based Heterostructures, Physical Review B, 86, 121104 (2012).

239. M Petrushevsky, E Lahoud, A Ron, E Maniv, I Diamant, I Neder, S Wiedmann, Vk Guduru, F Chiappini, U Zeitler, Jc Maan, K Chashka, A Kanigel, Y Dagan, Probing The Surface States In Bi2 Se3 Using The Shubnikov–De Haas Effect, Physical Review B, 86, 45131 (2012).

240. Yarden Mazor, Ben Z. Steinberg, Longitudinal Chirality, Enhanced Non-Reciprocity, And

241. Nano-Scale Planar One-Way Plasmonic Guiding, Physical Review B, 86, 15785786 (2012).

242. Yakir Hadad, Ben Z. Steinberg, One Way Optical Waveguides For Matched Non-Reciprocal

243. Nanoantennas With Dynamic Beam Scanning Functionality, Physical Review B, 21(S1), A77-A83 (2013).

244. Yakir Hadad, Yarden Mazor, And Ben Z. Steinberg, Green’S Function Theory For One-Way Particle Chains, Physical Review B, 87, 12137021 (2013).

245. Yakir Hadad, Ben Z. Steinberg, Quasistatic Resonance Of A Chemical Potential Interruption In A Graphene Layer And Its Polarizability: The Mixed-Polarity Semilocalized Plasmon, Physical Review B, 88, 26859574 (2013).

246. Nicholas P. Breznay, Hanno Volker, Alexander Palevski, Riccardo Mazzarello, Aharon Kapitulnik, And Matthias Wuttig, Weak Antilocalization And Disorder-Enhanced Electron Interactions In Annealed Films Of The Phase-Change Compound Gesb2Te4, Physical Review B, 86, 74291061 (2012).

247. D. Rakhmilevitch, I. Neder, M. Ben Shalom, A. Tsukernik, M. Karpovski, Y. Dagan, And A. Palevski, Anomalous Response To Gate Voltage Application In Mesoscopic Laalo3/Srtio3 Devices, Physical Review B, 87, 45110742 (2013).

248. Qi I. Yang, Merav Dolev, Li Zhang, Jinfeng Zhao, Alexander D. Fried, Elizabeth Schemm, Min Liu, Alexander Palevski, Ann F. Marshall, Subhash H. Risbud, And Aharon Kapitulnik, Emerging Weak Localization Effects On A Topological Insulator–Insulating Ferromagnet (Bi2Se3-Eus) Interface, Physical Review B, 88, 081407(R)/1-4 (2013).

249. Nimrod Bachar, Shachar Lerer, Shay Hacohen-Gourgy, Boaz Almog, Guy Deutscher, Kondo-Like Behavior Near The Metal-To-Insulator Transition Of Nanoscale Granular Aluminum, Physical Review B, 87, 214512-1 214512-4 (2013).

250. Eial Teomy And Yair Shokef, Jamming Transition Of Kinetically-Constrained Models In Rectangular Systems, Physical Review E, 86, 51133 (2012).

251. Nimrod Bachar,Shachar Lerer, Shay Hacohen Gourgy, Boaz Almog, Guy Deutscher, Kondo-Like Behavior Near The Metal-To-Insulator Transition Of Nano-Scale Granular Aluminum, Physical Review Letters, Na, 5 (2012).

252. Yair Shokef & Samuel A Safran, Scaling Laws For The Response Of Nonlinear Elastic Media With Implications For Cell Mechanics, Physical Review Letters, 108, 178103 (2012).

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PUBLICATIONS

253. Ido Dolev, Ido Kaminer, Asia Shapira, Mordechai Segev And Ady Arie, Experimental Observation Of Self-Accelerating Beams In Quadratic Nonlinear Media, Physical Review Letters, 108, 113903 (2012).

254. Noa Voloch-Bloch, Keren Shemer, Asia Shapira, Roy Shiloh, Irit Juwiler And Ady Arie, Twisting Light By Nonlinear Photonic Crystals, Physical Review Letters, 108, 233902 (2012).

255. S. Yogev, R. Matsubara, M. Nakamura, U. Zschieschang, H. Klauk, Y. Rosenwaks, Fermi Level Pinning By Gap States In Organic Semiconductors, Physical Review Letters, 110, 036803-1 (2013).

256. Z Salman, O Ofer, M Radovic, H Hao, M Ben Shalom, Kh Chow, Y Dagan, Md Hossain, Cdp Levy, Wa Macfarlane, Gm Morris, L Patthey, Mr Pearson, H Saadaoui, T Schmitt, D Wang, Rf Kiefl, Nature Of Weak Magnetism In Srtio_ {3}/Laalo_ {3} Multilayers, Physical Review Letters, 109, 257207 (2013).

257. Ido Dolev, Itai Epstein And Ady Arie “Surface Plasmons Holographic Beam Shaping, Surface Plasmons Holographic Beam Shaping, Physical Review Letters, 109, 203903 (2012).

258. Qi I. Yang, Merav Dolev, Li Zhang, Jinfeng Zhao, Alexander D. Fried, Elizabeth Schemm, Min Liu, Alexander Palevski, Ann F. Marshall, Subhash H. Risbud, And Aharon Kapitulnik, Emerging Weak Localization Effects On A Topological Insulator–Insulating Ferromagnet (Bi2Se3-Eus) Interface, Physiical Review B, 88, 081407(R)/1-5 (2013).

259. N.Parkansky, E. Faktorovich Simon, B. Alterkop, R L. Boxman, O. Berkh,, Decomposition Of Dissolved Methylene Blue In Water Using A Submerged Arc Between Titanium Electrodes, Plasma Chem Plasma Process, 33, 907-919 (2013).

260. N.Parkansky, A.Vegerhof, B.Alterkop, O.Berkh , Rl. Boxman, Submerged Arc Breakdown Of Methylene Blue In Aqueous Solutions, Plasma Chem Plasma Process., 32, 933-947 (2012).

261. N. Parkansky, A. Vegerhof, B. Alterkop, O. Berkh, R.L. Boxman, Submerged Arc Breakdown Of Methylene Blue In Aqueous Solutions" Plasma Chemistry And Plasma Processing, Plasma Chemistry And Plasma Processing, 32, 933-947 (2012).

262. Shay Halamish, Gennady Eidelshtein, Alexander Kotlyar, Plasmon-Coupled Nanostructures Comprising Finite Number Of Gold Particles, Plasmonics, 8, 745-748 (2013).

263. Halamish S, Eidelshtein G, Kotlyar A., Plasmon-Coupled Nanostructures Comprising Finite Number Of Gold Particles., Plasmonics, 8, 1557-1963 (2012).

264. Alexandra Dana, Tamir Tuller, Determinants Of Translation Elongation Speed And Ribosomal Profiling Biases In Mouse Embryonic Stem Cells., Plos Comput Biol., 8, E1002755 (2012).

265. Hadas Zur, Tamir Tuller, New Universal Rules Of Eukaryotic Translation Initiation Fidelity., Plos Comput Biol., 9, E1003136. (2013).

266. Alexandra Dana, Tamir Tuller, Determinants Of Translation Elongation Speed And

Ribosomal Profiling Biases In Mouse Embryonic Stem Cells., Plos Comput Biol., 8, E1002755 (2012).

267. Ronit Satchi-Fainaro, Shiran Ferber, Ehud Segal, Lili Ma, Niharika Dixit, Ambreen Ijaz, Lynn Hlatky, Amir Abdollahi, Nava Almog, Prospective Identification Of Glioblastoma Cells Generating Dormant Tumors, Plos One, 7(9), E44395 (2012).

268. Zaritsky A, Natan S, Ben-Jacob E, Tsarfaty I., Emergence Of Hgf/Sf-Induced Coordinated Cellular Motility., Plos One, 7, E44671 (2012).

269. Dahan L., Huang L., Kedmi R., Behlke Ma, And Peer D, Snp Detection In Mrna In Living Cells Using Allele Specific Fret Probes., Plos One, 8(9), E72389 (2013).

270. Shmueli, M.D., Schnaider, L., Rosenblum, D., Herzog, G., Gazit, E., And Segal, D., Structural Insights Into The Folding Defects Of Oncogenic Pvhl Lead To Correction Of Its Function In Vitro, Plos One, 8, E66333 (2013).

271. Avital Parnas, Shahar Nisemblat, Celeste Weiss, Galit Levy-Rimler, Amir Pri-Or, Tsafrir Zor, Peter Lund, Peter Bross, Abdussalam Azem, Identification Of Elements That Dictate The Specificity Of Mitochondrial Hsp60 For Its Co-Chaperonin, Plos One, 7, E50318 (2012).

272. Stein Gy, Yosef N, Reichman H, Horev J, Laser-Azogui A, Berens A, Resau J, Ruppin E, Sharan R, Tsarfaty I., Met Kinetic Signature Derived From The Response To Hgf/Sf In A Cellular Model Predicts Breast Cancer Patient Survival., Plosone, 7, 1 (2012).

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PUBLICATIONS

273. Tsarfaty I, Ben-Jacob E., Secrets Of Tubule Engineering By Epithelial Cells., Pnas, 109, 6790-1 (2012).

274. Polyak D, Eldar-Boock A, Baabur-Cohen H And Satchi-Fainaro R, Polymer Conjugates For Focal And Targeted Delivery Of Drugs, Polymers For Advanced Technologies, 24, 777–790 (2013).

275. K. Jain, D. Ghosh, R. Baer, E. Rabani, And A. P. Alivisatos, Near-Field Manipulation Of Spectroscopic Selection Rules On The Nanoscale, Proceedings Of The National Academy Of Science Usa, 109, 8016–8019 (2012).

276. Shock, I., Barbul, A., Girshovitz, P., Nevo, U., Korenstein, R., Shaked, N.T., Optical Phase Measurements In Red Blood Cells Using Low-Coherence Spectroscopy, Progress In Biomedical Optics And Imaging - Proceedings Of Spie, 8230, Art. No. 82300D (2012).

277. Roni Pozner, Gideon Segev, Rona Sarfaty, Abraham Kribus And Yossi Rosenwaks, Vertical Junction Cells For Concentrating Photovoltaics, Progress In Photovoltaics: Research And Applications, 20, 197-208 (2012).

278. Nachmias D, Sklan Eh, Ehrlich M, Bacharach E., Human Immunodeficiency Virus Type 1 Envelope Proteins Traffic Toward Virion Assembly Sites Via A Tbc1D20/Rab1-Regulated Pathway., Retrovirology, 9, 7 (2012).

279. Vanossi A., Manini N., Urbakh M., Zaperri S. And Tosatti E., Modeling Friction: From Nanoscale To Mesoscale, Rev. Mod. Phys., 85, 529-551 (2013).

280. Shelly Mahlab, Tamir Tuller, Michal Linial, Conservation Of

The Relative Trna Composition In Healthy And Cancerous Tissues, Rna, 18, 640-52 (2012).

281. Capozza R., Barel I. And Urbakh M., Probing And Tuning Frictional Aging At The Nanoscale, Sci. Rep., 3, 1896 (2013).

282. Primoz Peterlin, Vesna Arrigler, Emir Haleva, Haim Diamant, Law Of Corresponding States For Osmotic Swelling Of Vesicles, Soft Matter, 8, 2185-2193 (2012).

283. Yair Shokef, Yilong Han, Anton Souslov, Arjun G. Yodh, And Tom C. Lubensky, Buckled Colloidal Monolayers Connect Geometric Frustration In Soft And Hard Matter, Soft Matter, 9, 6565 (2013).

284. F. Brau, P. Damman, H. Diamant, T. A. Witten, Wrinkle To Fold Transition: Influence Of The Substrate Response, Soft Matter, 9, 8177-8186 (2013).

285. J. Baier, J. Lehmann, S. Lehmann, T. Rissom, C. A. Kaufmann, A. Schwarzmann, Y. Rosenwaks, M. Ch. Lux-Steiner, And S. Sadewasser, Electronic Properties Of Grain Boundaries In Cu(In,Ga)Se2 Thin Films With Various Ga-Contents, Solar Energy Materials & Solar Cells, 103, 86-92 (2012).

286. Gideon Segev, Y. Rosenwaks, And A. Kribus, Efficiency Of Photon Enhanced Thermionic Emission Solar Converters, Solar Energy Materials & Solar Cells, 107, 125–130 (2012).

287. K. Goldshtein, D. Golodnitsky E. Peled, L. Adler-Abramovich, E. Gazit, S. Khatun, P. Stallworth, S. Greenbaum, Effect Of Peptide Nanotube filler On Structural And Ion-Transport Properties Of Solid Polymer Electrolytes, Solid State Ionics, 220, 39–46 (2012).

288. K. Goldshtein, D. Golodnitsky E. Peled, L. Adler-Abramovich, E. Gazit, S. Khatun, P. Stallworth, S. Greenbaum, Effect Of Peptide Nanotube filler On Structural And Ion-Transport Properties Of Solid Polymer Electrolytes, Solid State Ionics, 6, 39-46 (2012).

289. Liat Benayoun, Svetlana Gingis-Velitski, Tali Voloshin, Ehud Segal, Rotem Segev, Michal Munster, Rotem Bril, Ronit Satchi-Fainaro, Stefan J. Scherer, Yuval Shaked, Tumor-Initiating Cells Of Various Tumor Types Exhibit Differential Angiogenic Properties And React Differently To Antiangiogenic Drugs, Stem Cells, 30(9), 1831-41 (2012).

290. Guy Deutscher, Point Contact Spectroscopy In Strongly Correlated Systems, Strongly Correlated Systems: Experimental Methods, 1, 41305 (2013).

291. Dana Bar-On, Steve Wolter, Sebastian Van De Linde, Mike Heilemann, German Nudelman, Esther Nachliel, Menachem Gutman, Markus Sauer And Uri Ashery., Super-Resolution Imaging Reveals The Internal Architecture Of Nano-Sized Syntaxin Clusters, The Journal Of Biological Chemistry, 287(32), 27158-67 (2012).

292. Ben M. Maoz, Rob Van Der Weegen, Zhiyuan Fan, Alexander O. Govorov, George A. Ellestad, Nina Berova, E. W. Meijer, Gil Markovich, Plasmonic Chiroptical Response Of Silver Nanoparticles Interacting With Chiral Supra-Molecular Assemblies, The Journal Of The American Chemical Society, 134, 17807–17813 (2012).

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67 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

• David Andelman, Nano Imprint Lithography using Copolymers with Henri Orland, Jean Daillant, Patrick Guenoun, CE-Saclay, CEA, France, Funding: BSF

• David Andelman, Nano Imprint Lithography using Copolymers with Henri Orland, Jean Daillant, Patrick Guenoun, CE-Saclay, CEA, France, Funding: BSF

• Jacob Scheuer, assembly of nano-particles using light with Tamar Seidman, Northwestern University, USA

• Prof. Meital Zilberman, Composite alginate hydrogels with controlled release of hydrophobic drugs with Prof. Havazelet Bianco-Peled, Technion, Israel

• Prof. Meital Zilberman, Release Mechanisms of Antiproliferative Drugs from Highly Porous Bioresorbable Structures with Prof. Yoel Kloog, Tel-Aviv Unversity, Israel, Funding: ISF

• Alexander Gerber, Development of magnetoelectronic devices for printed electronics with Prof. Gil Markovich, Tel-Aviv Unversity, Israel, Funding: KAMIN program

• Ella Sklan, dengue virus non-structural protein 4A with Dieter Willbold, Forschungszentrum Juelich GmbH, Germany

• Daniel, Segal, Structural studies of teh Drosophila p53 homolog with Prof. Alan Fersht, University of Cambridge, UK, Funding: ISF

• Eran Rabani, Metastability in Pressure-Induced Structural Transformations of CdSe/ZnS Core/Shell Nanocrystals with Prof. Paul Alivisatos, and Prof. Phill Geissler, Berkeley, USA

• Eran Rabani, How to Dope Semiconductor Nanocrystals with Prof. Uri Banin and Prof. Anatoly

Frenkel, Hebrew University, Yeshiva University, Israel, USA,

• Eran Rabani, The Electronic Structure of CdSe/CdS Core/Shell Seeded Nanorods: Type-I or Quasi-Type-II? with Dr. Michael Grunwald, Vienna, Austria, Funding: EU project

• Eran Rabani, Self-Averaging Stochastic Kohn-Sham Density Functional Theory with Prof. Roi Baer and Prof. Daniel Neuhauser, Hebrew University, UCLA, Israel, USA, Funding: ISF

• Eran Rabani, Unraveling the Impurity Location and Binding in Heavily Doped Semiconductor Nanocrystals; The Case of Cu in InAs Nanocrystals with Prof. Anatoly Frenkel and Prof. Uri Banin, Hebrew University, Yeshiva University, Israel, USA, Funding: TAU Nanocenter

• Eran Rabani, Bistability in A Quantum System With Electron-Phonon Interactions Under Finite Bias with Prof. Michael Thoss and Prof. Haobin Wang, Erlangen/New Mexico State University, USA, Germany, Funding: EU project

• Eran Rabani, Biexciton Generation Rates in CdSe Nanorods Are Length Independent with Prof. Roi Baer, Hebrew University, Israel, Funding: ISF

• Eran Rabani, Numerically Exact Long Time Magnetization Dynamics at the Nonequilibrium Kondo Crossover of the Anderson Impurity Model with Prof. Andrew Millis, Prof. David Reichman, Prof. Emanuel Gull, Columbia/Michagan, USA, Funding: BSF

• Eran Rabani, A Cartesian Quasi-classical Model to Nonequilibrium Quantum Transport: The Anderson

Impurity Model with Prof. Bill Miller, Berkeley, USA

• Eran Rabani, Expeditious Stochastic Approach for MP2 Energies in Large Electronic Systems with Prof. Daniel Neuhauser, Prof. roi Baer, Hebrew University, UCLA, Israel, USA, Funding: ISF

• Eran Rabani, Multiexciton Generation in IV-VI Nanocrystals: The Role of Carrier Effective Mass, Band Mixing, and Phonon Emission with Prof. Roi Baer, Hebrew University, Israel, Funding: ISF

• David Sprinzak, dSTORM of membrane proteins with Markus Sauer, Wuerzburg University, Germany, Funding: ISF

• Dan Peer, Therapeutic gene silencing in blood cancer using targeted nanoparticles with Judy Lieberman, Timothy Springer, Harvard University, USA, Funding: NIH

• Dan Peer, Harnessing nanomedicines as microbicides with Derek Dyxehoorn, University of Miami, USA, Funding: NIH

• Dan Peer, Harnessing immuno-nanomedicines for theranostics systems with Alan Packard, Harvard University, USA, Funding: Helmsely Trust for IBD

• Ori Cheshnovsky, Molecular interference with Prof. Markus Arndt, Vienna University, Austria, Funding: EU project

• David Sprinzak, Micropatterning devices for studying intercellular signaling with Christopher Chen, UPenn, USA, Funding: ISF

• Rafi Korenstein, Exploring the interaction of hybrid quantum dots with cells with Prof. Yoon-Sik Lee, National University Seoul, Korea, Funding: Ministry of Science and Technology

Collaborative Projects

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68 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

COLLABORATIVE PROJEC TS

• Rafi Korenstein, Exploring the interaction of hybrid quantum dots with cells with Prof. Yoon-Sik Lee, National University Seoul, Korea, Funding: Ministry of Science and Technology

• Rafi Korenstein, Predictive toxicology of engineered nanoparticles with Prof. Emilio Benfenati, Mario Negri, Milano, Italy, Funding: EU project

• Rafi Korenstein, Predictive toxicology of engineered nanoparticles with Prof, Gerhard Gompper, Forschungszentrum Jülich , Germany, Funding: EU project

• Yossi Rosenwaks, Dopants in Nanowires with David Seidman and L.J. Lauhon, Northwestern University, USA, Funding: BSF

• Yossi Rosenwaks, Dopants in Nanowires with Roie Yerushalmi, Hebrew University, Israel, Funding: BSF

• Yossi Rosenwaks, Organic Transistors with H. Klauke, Max Planck Stutgart, Germany

• Yossi Rosenwaks, InAs Nanowires with Hadas Shtrikman, Weizmann Institute, Israel, Funding: MOS

• Yossi Rosenwaks, InP Nanowires with Dan Ritter, Technion, Israel, Funding: MOS

• Ilan Goldfarb, Magnetic Properties of Self-Organized Nanostructure Arrays: The Effects of Size, Proximity, and Mesoscopic Ordering with Amit Kohn, Ben-Gurion University, Israel, Funding: ISF

• Yael Hanein, Nano-materials for optical activation of cells with Uri Banin, Hebrew University, Israel, Funding: MOST

• Yael Hanein, Astrocytic regulation of neuronal activity with Hugues Berry, Université de Lyon LIRIS

UMR5205, France, Funding: MOST (Israel-France)

• Yael Hanein, Nanorectenna with Koby Scheuer, Amir Boag, Tel-Aviv Unversity, Israel, Funding: Israel Strategic Alternative Energy Foundation

• Yoram Dagan, Spin-orbit interaction in oxide interfaces with Harold Y Hwang, Stanford, USA, Funding: BSF

• Yoram Dagan, Low dimensional electronic systems with MIsha Reznikov, Amit Kanigel, Technion, Israel, Funding: MOST

• Diana Golodnitsky, Modeling the effect of adsorbed polyelectrolytes on the potential at charged particles for electrophoretic deposition with Amir Natan, Tel-Aviv Unversity, Israel, Funding: ICORE

• Diana Golodnitsky, Towards a novel sodium-air battery for EV application with Prof. Steve G. Greenbaum, Hunter college, NY, USA, Funding: BSF

• Diana Golodnitsky, Petroleum Alternatives for Transportation- Israel National Research Center for Electrochemical Propulsion with Prof. Doron Aurbach, Bar-Ilan University, Israel, Funding: ISF

• Itai Benhar, Bactreia-based nanoprticles with Avi Schroeder, Technion, Israel

• Itai Benhar, targeted anti fungal nanomedicines with Nir Osherov, Tel-Aviv Unversity, Israel

• Moshe Portnoy, Synthesis and study of organocatalysts tethered to dendronized polymer support with Prof. Scott J. Miller, Yale University, USA, Funding: BSF

• Moshe Portnoy, Dendritic platforms with NIR turn-on fluorescent core with Prof. Doron

Shabat, Tel-Aviv Unversity, Israel, Funding: INNI

• Inna Slutsky, Alzheimer's disease mechanisms with Dominic Walsh-Harvard, Ehud Isacoff-UC Berkeley, Harvard, Berkeley, USA, Funding: ERC

• Ronit Satchi-Fainaro, Oligonucleotide Delivery to Cancer with Rainer Haag, Frei University of Berlin, Germany, Funding: GIF

• Ronit Satchi-Fainaro, Theranostic probes with Doron Shabat, Tel-Aviv Unversity, Israel, Funding: INNI

• Ronit Satchi-Fainaro, Circulating endothelial cells with Yuval Shaked, Technion, Israel, Funding: ISF

• Ronit Satchi-Fainaro, Targeted nanomedicines to integrin-expressing cancers with Maria Jesus Vicent, CIPF, Spain, Funding: ISF

• Abraham Nitzan, Surface electronic processes with Ron Naaman, David Cahen, Leeor Kronik (WIS), Haim Sukenik (BIU), Weizmann Institute, Bar-Ilan University, Israel, Funding: ISF

• Ronit Satchi-Fainaro, Targeted nanomedicines to integrin-expressing cancers with Ruth Lupu, Mayo Clinic, USA, Funding: BSF

• Abraham Nitzan, Molecular plasmonics with Tamar Seideman, Northwestern University, USA, Funding: BSF

• Abraham Nitzan, Molecular electroinics for photovoltaic cells with Mark Ratner, Northwestern University, USA, Funding: BSF

• Yoram Selzer, Time resolved conductance measurement of molecular junctions with Prof. Volkhard May, Humboldt University in Berlin, Germany, Funding: GIF

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69 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

COLLABORATIVE PROJEC TS

• Ben Z. Steinberg, Prof with Prof. Nader Engheta, University of Pennsylvania, USA, Funding: N/A

• Amir Goldbourt, Oxide surface chemistry with Roie Yerushalmi, Hebrew University, Israel, Funding: N/A

• Amir Natan, All Oxide photovoltaics with Arie Zaban, Sven Ruhle, Bar-Ilan University, Israel, Funding: MOITAL

• Amir Natan, INREP with Emanuel Peled, Diana Golodnitsky, Tel-Aviv Unversity, Israel, Funding: ISF

• Alexander Palevski, Topological Insulators with Professor Kapitulnik, Stanford University, USA, Funding: BSF

• Alexander Palevski, Quantum nanowires with Hadas Shtrickman and Moty Heiblum, Weizmann Institute, Israel, Funding: ISF

• Ron Lifshitz, Nanomechanics (NEMS) with Michael Cross, Michael Roukes, Keith Schwab, Caltech, USA, Funding: BSF

• Haim Diamant, Response of actin networks with Yael Roichman, Tel-Aviv University, Israel, Funding: ISF

• Haim Diamant, Orientational alignment of colloids with Thomas A. Witten, University of Chicago, USA

• Haim Diamant, Patterns in fluid-supported thin sheets with Thomas A. Witten, University of Chicago, USA, Funding: BSF

• Haim Diamant, Dynamics of confined colloids with Stuart A. Rice, Binhua Lin, University of Chicago, USA, Funding: ISF

• Haim Diamant, Heterogeneously charged surfaces in solution with David Andelman, Tel-Aviv University, Israel

• Uri Ashery,Nanometric organization of SNARE proteins

using super resolution microscopy with Prof. Markus Sauer, Wuerzburg University, Germany, Funding: GIF

• Ady Arie, Engineering Nonlinear Plasmonics with Yosi Lareah, Tel-Aviv Unversity, Israel, Funding: ISF

• Noam Eliaz, Electroless and electroplating of rhenium-based alloys with Prof. Eliezer Gileadi, Tel-Aviv University

• , Tel-Aviv Unversity, Israel, Funding: AFOSR + MAFAT

• Noam Eliaz, Electroless plating of rhenium-based alloys with Dr. Alexandra Inberg, Tel-Aviv University, Israel, Funding: AFOAR + MAFAT

• Noam Eliaz, Preparation and characterization of alkylphosphonic acid self-assembled monolayers on titanium alloy by chemisorption and electrochemical deposition with Prof. Dani Mandler, Hebrew University, Israel, Funding: HUJI

• Noam Eliaz, The use of Atom Probe Tomography (APT) to study the chemistry and structure of rhenium-based coatings on atomic scale with Prof. David Seidman, Northwestern University, USA, Funding: AFOSR + MAFAT

• Michael Urbakh, Probing and Manipulating Biomolecules: From Single Molecules to an Ensemble with Hermann E. Gaub, Matthias Rief, Matthias Weiss, Yoav I. Henis, Joseph Klafter, Rony Granek, Amir Aharoni, Tel-Aviv Unversity, Ben-Gurion University, Ludwig-Maximilians-Universität München, Technische Universität München, Israel, Germany, Funding: DIP

• Judith Rishpon, ELECTROCHEMICAL APTAMER AND IMMUNO BIOSENSORS FOR FAST AND SENSITIVE MONITORING

OF PATHOGENS IN WATER with Abid Nasser, Beate Strehlitz, Bar-Ilan University, Israel, Germany, Funding: BMBF

• Gil Markovich, Printable magneto-electronic devices with Alexander Gerber, Tel-Aviv Unversity, Israel, Funding: Kamin, OCS

• Chanoch Carmeli, Electron transfer in proteins with David Cahen, Weizmann Institute, Israel, Funding: Wolfson Fund

• Chanoch Carmeli, Spin in photosystem with Ron Naaman, Weizmann Institute, Israel, Funding: Wolfson Fund

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70 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

COOPERATION WITH THE INDUSTRY

• PI: Prof. Dan Peer, Topic: Developing targeted nanoparticles toward sarcoma, Quark Pharmaceuticals, Rehovot , Israel

• PI: Prof. Dan Peer, Topic: Developing targeted nanoparticles for delivery of therapeutic proteins into the brain, Shire Lexington, USA

• PI: Prof. Dan Peer, Topic: Development of the Gagomer platform technology, Quiet Therapeutics, Ness Ziona, Israel

• PI: Prof. Dan Peer, Topic: Development of specialized fusion protein for targeted therapy of cancer and inflammation, Roche Basal, Switzerland

• PI: Prof. Yossi Rosenwaks, Topic: Electrostatic Nanowires, Tower-Jazz, Migdal-Haemek, Israel

• PI: Prof. Yossi Rosenwaks, Topic: Poly-Si Nanowires, Micron Kiryat Gat, Israel

• PI: Prof. Ilan Goldfarb, Topic: Electronic Structure and Properties of Thin Transition-Metal Oxide Films for Memristor Technology, R. Stanley Williams Hewlett-Packard Laboratories, 1501 Page Mill Rd, Palo Alto, CA 94304 USA

• PI: Prof. Yael Hanein, Topic: Brain technology, Alpha Omega Nazareth, Israel

• PI: Prof. Yael Hanein, Topic: Artificial Retina, Nano retina Herzelia

Cooperation with the Industry

• PI: Andrey Godkin, Topic: EFN, Tower Jazz, Migdal Haemek, Israel

• PI: Prof. Diana Golodnitsky, Topic: Advanced Energy and Power Technologies for Automotive Electrification, Tadiran batteries, Israel

• PI: Ady Arie, Topic: Frequency conversion and beam shaping of high energy beam by transverse quasi-phase-matching, Ramot Tel Aviv, Israel

• PI: Judith Rishpon, Topic: Early warning bio-electrochemical sensors for detection of acute contamination in drinking water, Mekorot, Israel

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71 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

Managing Staff

Prof. Yael Hanein Director

Dr. Nava Ariel-Sternberg Managing Director

Dr. Inbal Halevi FTA manager

Ms. Ronit Timor Administrative Assistant

Ms. Noa Shafir Secretary

Scientific Committee

Prof. Ori Cheshnovsky School of Chemistry (Chairperson)

Prof. Rimona Margalit Faculty of Life Sciences

Prof. Yossi Rosenwaks School of Electrical Engineering

Prof. Yoram Dagan School of Physics & Astronomy

Prof. Yael Hanein School of Electrical Engineering (Director)

Prof. Fernando Patolsky School of Chemistry

Prof. Dan Peer Faculty of Life Sciences

Prof. Jacob Scheuer School of Electrical Engineering

Dr. Inna Slutsky Faculty of Medicine

Core Members

Prof. Shachar Richter Department of Materials Science and Engineering

Prof. Yael Hanein School of Electrical Engineering

Prof. Fernando Patolsky School of Chemistry

Prof. Koby Scheuer Electrical Engineering

Prof. Dan Peer Faculty of Life Sciences

Dr. Roy Beck-Barkai School of School of Physics & Astronomy

Center Researchers and Technical Staff (MNCF)

Dr. Nava Ariel-Sternberg Managing Director

Dr. Yigal Lilach Electron & Ion Beam Lithography & Microscopy manager

Dr. Artium Khatchatouriants Bio-AFM laboratory manager

Mr. Valery Gerber Process engineer & Business development

Dr. David Schriber Process engineer

Dr. Alex Gurevitch Process engineer

Staff

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72 THE CENTER FOR NANOSCIENCE AND NANOTECHNOLOGY AT TEL AVIV UNIVERSITY

STAFF

Dr. Alex Pevzner Process engineer

Mr. Alex Epstein Equipment engineer

Mr. Gidon Jacob Equipment engineer

Mrs. Inna Veksler Fiscal administrator

Student positions (MNCF)

Mr. Youry Borisenkov MNCF process engineer

Mr. Yoni Kantarovski HRSEM operator

Ms. Edit Beilis FTIR operator and Glove box evaporator (student position)

Ms. Michal Eithan RAITH and JEOL 6400 operator

Ms. Shoshy Mizrachy Zeta Potential operator (student position)

Mr. Daniel Azulay TEM operator

Mr. Itai Epstein Thin film deposition training