THE 1ST « HEALTH-ENTERTAINMENT » PREVENTION COACHING SYSTEM DEDICATED TO PREDIABETIC INDIVIDUALS

REGINALD ALLOUCHE, MD

PREDIABETES & TYPE 2 DIABETES: ALARMING WORLD PERSPECTIVE

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T2 DIABETES (ADULTS): u 415 million people

u 44.5% of them live in China, the Middle East and the USA

REGIONAL TRENDS ARE EVEN WORSE…Ø Just over a decade ago, T2D was very rare in China vs. 1 out of 2 Adults being

prediabetics nowadays

Ø Middle East has the highest T2 diabetes worldwide prevalence (T2 Diabetics will double - 59.7M - by 2030)

REGION T2DIABETES PREDIABETES

CHINA 114M 493MMIDDLEEAST 26M 116MUSA 29M 87M

TOTAL 169M 696M

8.8%of worldwidepopulation

PREDIABETES & TYPE 2 DIABETES: US SITUATION

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T2 DIABETES IS ONE OF THE MAJOR MEDICAL DANGER FACED BY THE US u T2 DIABETES IS THE LEADING CAUSE OF BLINDNESS, KIDNEY FAILURE, NON-TRAUMATIC

AMPUTATION OF FEET AND LEGS, IMPOWER, etc.u A PERSON WITH T2 DIABETES HAS A SHORTER LIFE EXPECTANCY AND ABOUT TWICE THE RISK

OF DYING FROM CANCER OR NEURO-DEGENERATIVE DISEASE.u T2 DIABETES IS THE SEVENTH LEADING CAUSE OF DEATHS.

* CDC National Diabetes Statistics Report - 2014

*

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87 Million people with prediabetes1 out of 3 US adults has prediabetes15-30% will develop T2 diabetes within 5 year

29,1 Million T2 Diabetics (Diagnosed + Undiagnosed)

US$ 245B FINANCIAL COST OF DIABETES*$176 billion direct medical costs$69 billion indirect costs: healthcare services, disability, work loss.

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PREDIABETESà T2DIABETESANIGHTMAREFORTHECOUNTRY

Year Percentage Number (M)

2012 6.96 21.47

2013 7.18 22.30

2014 7.02 21.95

Number & Percentage of US Population with Diagnosed T2 Diabetes

Prediabetes (1 out of 3 Adults Have Prediabetes)2012 2015

79 M 87 M

TOTAL 29.1 M

Diagnosed 21 M

Undiagnosed 8.1M

Diabetes Financial Cost

2015 $245 Billion

Total medical costs and lost work and wages for people withdiagnosed T2 diabetes

PREVENTING DIABETES IS THE ONLY SOLUTION!

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GOOD NEWS: T2 DIABETES IS REVERSIBLE & PREVENTABLE AT THE STATE OF PREDIABETES

u PREDIABETES LASTS 5 TO 15 YEARS BEFORE T2 DIABETES

u PREDIABETES IS A WARNING SIGN THAT A PATIENT IS HEADING TOWARD DANGER, BUT HAS NOT YET REACHED THE TIPPING POINT.

DIAGNOSTIC NORMAL PREDIABETES T2 DIABETES

FASTING GLYCEMIA

0,7 to 1,04 g/l 1,05 to 1,26 g/l > 1,26 g/l

A major clinical study led by the CDC proved that a 5-7% weight losspaired with Increased physical activity could prevent or delay theprogression to Type 2 Diabetes by 58%.

This led to the National Diabetes Prevention Program (NDPP).

PREVENTION IS NOW A US GOVERNMENT PRIORITY

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THE NATIONAL DIABETES PREVENTION PROGRAM IN THE USA(US. Dept of Health and Human Services, State of Massachussets, NIH, CDC)

After an audit led by the CDC mostly on companies/program application compliance with the CDC guidance,

only few digital players entered the market recently…

1) THERE IS NOT ENOUGH PHYSICIANS FOR FORPREVENTION ACTION

2) SMARTPHONES ARE PERFECT TERMINALS TOPROVIDE ADVICES AND FOLLOW-UP

3) NETWORK INFRASTRUCTURE IS PAID BY END-USERS!

PARADIGMSHIFT!

+

7

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Prediabaid: REVERSING PREDIABETES

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THE VERY 1ST “HEALTH-ENTERTAINMENT” PREVENTION COACHING METHOD DEDICATED

TO INDIVIDUALS WITH PREDIABETES

+ =

“PREDIABAID COMBINES A CUTTING-EDGE DISEASE PREVENTION COACHING ARTIFICIAL INTELLIGENCE PROGRAM WITH HOLLYWOOD-STYLE ENTERTAINMENT EDUCATIONAL VIDEOS.” Dr. Reginald Allouche - Founder

Science Entertainment

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Prediabaid: REVERSING PREDIABETES

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s Based on (i) Science / Medicine (CDC recognition and state of Florida endorsement in 2016) and (ii) more than 30y+ of experiences

s Addresses Prediabetes directly & effectively (CUT THE RISK TO BECOME T2 DIABETIC BY 57%) using the only integrated Diabetes Prevention Program in a convenient APP form.

s Increased users’ compliance and satisfaction: Unique method Integrating cutting edge devices and entertainment« Having a physical tool besides the smartphone makes it more a part of life’s prediabetic and the videos get smarter and more personalized; it keeps the process fun » Dr. Reginald Allouche

s A 1 billion company potential, in 5 years, with only 4% of the US Prediabetics (~340k people)

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PREDIABAIDISCOMPLYINGWITHCDCRECOMMENDATIONS

Fighting against Type2Diabetesis now aNationalCausefortheUS

THE SOLUTION

M E L S A O P I T C H D E C K C O N F I D E N T I A L

PREDIABAID IS A UNIQUE METHOD TRANSCRIBED INTO A MOBILE APP THAT PROVIDES THE GUIDANCE TO A PREDIABETIC PATIENT EQUIVALENT

TO DAILY CONSULTATIONS WITH A PHYSICIAN AND/OR A DIETITIAN

How PREDIABAID works ?

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APPROVED BY

1

PREDIABAID INTERFACE

DAILY INTERACTIONS

WITH USERS

DAILY ADVICES (RECIPES)

CLINICAL INFO TRACKING

CLINICAL INFO TRACKING

How PREDIABAID works ?

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THREE BLUETOOTH CONNECTED DEVICES “FEED” THE APP ON A WEEKLY OR DAILY BASIS: GLUCOMETER, WEIGHT SCALE WITH IMPEDANCE METER

& TRACKING MONITOR

TIFFANY HOFSTETTER“THE DIET COACH”

CHRISTOPHER MACK“THE LIFESTYLE COACH”

ALICIA MARTINEAU“REGINALD’S

RIGHT-HAND WOMAN”

THE DAILY FEEDBACK OF THE PREDIABAID APP IS DONE THROUGH CUSTOMIZED AND EDUCATIONNAL VIDEOS PLAYED BY TV SERIES ACTORS

2

3

How PREDIABAID works ?

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CONNECTED DEVICES

PERFORMANCE TRACKING

HOLLYWOOD-STYLE CUSTOMIZED VIDEOSUSER EXPERIENCE

USER COMPLIANCE

1 2

3

PREDIABAID METHODSCIENCE

DAILY MOBILE CONSUMPTION

2016:SUCCESSFULLFOCUSandTESTSGROUPSINLA

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MOBILE

ConnectedDevices

APP.

CRM FILES

RULES

REFERENTIAL

ARTIFICIAL INTELLIGENCE

SERVER

Architecture : A versatile Cloud-Base operating system

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BACK OFFICE

• HELP CENTER• SUPPORT• FORUM• CHAT• SOCIAL

CLIENT DATA FLOW

CONTROL SERVER

• PRIVACY • CONNECTIONS• DB MANAGT• ADMIN

BLOG

Website

DESKTOP

VIDEOSSERVER

PREDIABAID TEAM

M E L S A O P I T C H D E C K C O N F I D E N T I A L

PREDIABAID MANAGEMENT TEAM

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Dr. REGINALD ALLOUCHE, FOUNDER, CEO & Chief Medical OfficerFrench MD, the first “Diabetologist” of his kind. He is also an engineer, a research scientist, a serial successful entrepreneur and the author of 5 best-selling books in Europe and in the US.

REGINALD WITH PRESIDENTOBAMA AT THE WHITE HOUSE

FABIEN COUSIN, PARTNER, Chief Technology OfficerFabien is an engineer and held executive positions both in§ the public sector, as head of research in the area of therapeutic

assistance to diabetics at INSERM and as head of IT and healthcare networks with assistance Publique-Hôpitaux de Paris,

§ private groups as VP of IT with Expand Multimedia and Ceprodi-Kot.

He is also an entrepreneur and founder of several companies, including Mastersecurity, specialized in IT sucurity

u Just arrived : PHILIPPE MAROZEAU, PARTNER, Director of sales

u MELSAO IS GOVERNED BY ITS CHIEF EXECUTIVE OFFICER WITH THE ASSISTANCE OF AN ADVISORY BOARD COMPOSED OF FIVE MEMBERS.

² MR. REGINALD ALLOUCHEformer CTO at GlaxoSmithKline, COO at Assistance Publique Hopitaux de Paris, founder of Kot a French leading company in the dietetic industry

² MR. PASCAL ANSARTpartner of the strategy business unit of PWC

² MR. PHILIPPE DELMASformer vice-president of Airbus

² MR. CHRISTIAN BRABANTCEO ECOSYSTEMES

² MR. ROBERT CALLENSCEO IMMOCHAN RUSSIA

Governance – Advisory board

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