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A Human mutant Gln 355 (Blue) Chlamydomonas Gln 34
B
Helix α1 Helix α1
β-sheet β-sheet
3.4 Å
3.6 Å
Human mutant Asn 412 (Blue) Chlamydomonas Asn 96
2.8 Å3.0 Å
Arg 433 Arg 117
Helix α1Helix α1
β-sheet β-sheet
C Human mutant His 464 (Blue) Chlamydomonas His 147
3.0 Å2.9 Å
Arg 453Arg 136
β-sheet β-sheet
D Human mutant Asn 354 (Blue) Chlamydomonas Asn 33
Helix α1
β-sheet
Tyr 115
Trp 138
3.1 Å
3.1 Å
Helix α1
β-sheetTyr 431
Trp 455
3.0 Å
3.0 Å
Supplementary Figure 3
