Sources: Numerator=ICAP routine data as of December 2009; Denominator=WHO/UNAIDS/UNICEF, Towards Universal Access: Scaling Up Priority HIV/AIDS Interventions in the Health Sector, September 2010: http://www.who.int/hiv/pub/2010progressreport/report/en/index.html.

PROPORTION OF ART PATIENTS IN 8 AFRICAN COUNTRIES RECEIVING ART THROUGH DECEMBER

2009 AT TRACK 1.0 HIV CARE AND TREATMENT CLINICS, DECEMBER 2009

Overall (n=2,306,489)

Mozambique (n=170,198)

Rwanda (n=76,726)

Ethiopia (n=176,632)

Nigeria (n=302,973)

Tanzania (n=199,413)

South Africa (n=971,556)

Kenya-Track 1.0

(n=336,980)

Cote d'Ivoire (n=72,011)

0%

5%

10%

15%

20%

25%

30%

35%

9%

31%

24%

17%

10% 9%

5%4% 3%

Perc

ent o

f all

patie

nts

rece

ivin

g AR

T

Number of patients receiving Art as of December 20098 countries below: 2.3 millionICAP-supported programs: 215,000

ICAP coverage: 9%

PROPORTION OF PATIENTS WITH CD4 COUNT AT BASELINE, 6, AND 12 MONTHS AFTER ART INITIATION

AT TRACK 1.0 HIV CARE AND TREATMENT CLINICS, SEPTEMBER 2011(SUBSET OF ART PATIENTS*)

Source: ICAP routine data as of September 2011Notes: *Data only included for patients who were followed for 12 months.

Overall

n=243,497

Rwanda n=17,122

Côte d'Ivoire n=3,828

South Africa n=30,379

Ethiopia n=45,746

Nigeria

n=40,842

Kenya

n=16,111

Mozambique

n=67,060

Tanzania

n=22,409

0%

50%

100%

81%

97% 96% 94% 92%87%

79%

66%63%

45%

80%

60%

51% 50% 52%49%

25%

32%

44%

77%

51%

39%

48% 48%45%

34%36%

Baseline 6-month 12-month

P e r c e n t o f p a ti e n t s

TRENDS IN MEDIAN CD4 AT ART INITIATION AND 6 MONTH FOLLOW-UP: TRACK 1.0 HIV CARE AND

TREATMENT CLINICS

Jan-05 Jul-05 Jan-06 Jul-06 Jan-07 Jul-07 Jan-08 Jul-08 Jan-09 Jul-09 Jan-10 Jul-10 Jan-110

50

100

150

200

250

300

350

400

Median CD4 count at ART initiation Median CD4 count 6 months after ART initiation

Month/year of ART initiation

Med

ian

CD4

coun

t (ce

lls/u

L)

173 cells/uL 323 cohorts

318 cells/uL 323 cohorts

123 cells/uL 10 cohorts

290 cells/uL 10 cohorts

Sources: ICAP routine data as of September 2011

Sources: ICAP routine data as of September 2011

TRENDS IN MEDIAN CD4 AT ART INITIATION AND 12 MONTH FOLLOW-UP: TRACK 1.0 HIV CARE AND

TREATMENT CLINICS

Jan-05 Jul-05 Jan-06 Jul-06 Jan-07 Jul-07 Jan-08 Jul-08 Jan-09 Jul-09 Jan-10 Jul-100

50

100

150

200

250

300

350

400

Median CD4 count at ART initiation Median CD4 count at 12 month follow-up

Month/Year of ART initiation

Med

ian

CD4

coun

t (ce

lls/u

L)

130 cells/uL(7 cohorts)

166 cells/uL(287 cohorts)

342 cells/uL(287 cohorts)

300 cells/uL(7 cohorts)

MEDIAN CD4 COUNT AT BASELINE*, 6, AND 12 MONTHS AFTER ART INITIATION AT TRACK 1.0 HIV CARE AND TREATMENT CLINICS, SEPTEMBER 2011

(SUBSET OF ART PATIENTS**)

Source: ICAP routine data as of September 2011Notes: Average of median CD4 counts at baseline and 6 and 12 months follow up are presented.* Baseline data is average of matched 6 and 12 month cohort data at baseline.** Data only included for patients who were followed for 12 months..

Overall

n=243,497

Rwanda

n=17,122

Mozambique

n=67,060

Nigeria

n=40,842

Côte d'Ivoire

n=3,828

South Africa

n=30,379

Ethiopia n=44,45746

Kenya

n=16,111

Tanzania

n=22,409

0

50

100

150

200

250

300

350

400

450

150

237

173 169

131 129 128 128115

266

360

333

274

288

262247

257

185

297

395

356 347

244

300

273

299

208

Baseline 6-month 12-month

C D 4 C e ll C o u n t ( c e ll s / u l)

CHANGE IN MEDIAN CD4 COUNT AFTER 6 AND 12 MONTHS OF ART AT TRACK 1.0 HIV CARE AND

TREATMENT CLINICS, SEPTEMBER 2011 (SUBSET OF ART PATIENTS*)

Source: ICAP routine data as of September 2011Notes: Change in average of median CD4 counts at baseline and 6 and12 months follow up are presented.*Data only included for patients who were followed for 12 months.

Overall Mozambique South Africa Kenya Rwanda Ethiopia Nigeria Cote d'Ivoire Tanzania0

20

40

60

80

100

120

140

160

180

200

116

160

132 130123 119

105 104

71

147

183

171 171

158

145

178

113

93

6-month 12-month

Cha

nge

in m

edia

n C

D4

coun

t (ce

lls/µ

L)

MEDIAN CD4 COUNTS AT ENROLLMENT INTO HIV CARE ARE INCREASING AT TRACK 1.0 HIV CARE AND

TREATMENT CLINICS WITH PATIENT-LEVEL DATA, JUNE 2011 (n = 147 CLINICS)

Jan-05 Jul-05 Jan-06 Jul-06 Jan-07 Jul-07 Jan-08 Jul-08 Jan-09 Jul-09 Jan-10 Jul-10 Jan-110

100

200

300

400

500

Rwanda (40 clinics) Tanzania (41 clinics)Mozambique (28 clinics) Kenya (38 clinics)

Month/year of enrollment into HIV care

Med

ian

CD4

coun

t at e

nrol

lmen

t int

o HI

V ca

re

(cel

ls/u

L)

4 country average at Jan 05: 192 (1,682 pts)

4 country average at Jan 11: 297 (5,721 pts)

MEDIAN CD4 COUNTS AT ART INITIATION ARE INCREASING AT TRACK 1.0 HIV CARE AND

TREATMENT CLINICS WITH PATIENT-LEVEL DATA, JUNE 2011 (n = 147 CLINICS)

Jan-05

Jul-05

Jan-06

Jul-06

Jan-07

Jul-07

Jan-08

Jul-08

Jan-09

Jul-09

Jan-10

Jul-10

Jan-11

0

50

100

150

200

250

300

350

Rwanda (40 clinics) Tanzania (41 clinics)Mozambique (28 clinics) Kenya (38 clinics)

Month/Year of ART initiation

Med

ian

CD4

coun

t at A

RT in

itiat

ion

(cel

ls/u

L)

4 country average at Jan 05: 114 (842 pts)

4 country average at Jan 11: 213 (3,748 pts)