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A review of NPL audit Russell Thomas Radiation Dosimetry Group, National Physical Laboratory

Sound in Air - UK Dosimetry Audit Network · • ICRU 24 - Dose delivery to ... “Accurate dosimetry is not that important ... the provision of the complex radiotherapy that is,

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A review of NPL audit

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

A review of NPL audit

or

What are we actually trying to

achieve?

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

Monday, 13 January 2014

3

History

• 4th January 1994

• 1994 commenced IPEM/NPL

Photon MV reference dosimetry audits

• Linking the eight regional audit groups

• Later expanded into kV Photons and

Electrons (1996 & 2003)

• Support for development of Alanine based

services for Gamma Knife, Tomotherapy

Cyber knife, Protons and the National IMRT

audit & NRRA

Basic structure for all reference dosimetry audits:

• Beam quality

• Machine output

• Field instrument calibration

+ specific areas such as ion recombination

+ individual areas of concern

The easy “also checked”

• Temperature

• Pressure

• Laser Alignment

• SSD/Front pointer agreement

• Storage conditions of equipment

• Certification/calibration/ traceability

• Not Paper trails (if it’s written down and you

do it that’s a pass even if it’s not best

practice)

Monday, 13 January 2014

5

Audit is not just about getting two numbers

to agree within a tolerance.

• My Gray = Your Gray, PASSED

on to the next department…..

• My Gray = Your Gray, PASSED

on to the next department…..

• My Gray = Your Gray, PASSED

on to the next department…..

Monday, 13 January 2014

6

It’s about the touchy feely

stuff too….

7

It’s about the touchy feely

stuff too….

8

Auditing – a bit like

cracking a safe really!

Monday, 13 January 2014

9

MV photon audit

set up

Monday, 13 January 2014

11

0.9800

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

0 10 20 30 40 50 60 70

Rati

o N

PL

/Ho

st

Audit number

Beam quality index (TPR)

NPL/Host 0.998 std dev 0.5%

MV photon field

instrument calibration

0.9800

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

1.0200

0 10 20 30 40 50 60 70

Ra

tio

NP

L/H

os

t

Audit number

Field Instrument calibration

NPL/Host

1.001

std dev 0.7%

Monday, 13 January 2014

13

0.9850

0.9900

0.9950

1.0000

1.0050

1.0100

1.0150

1.0200

1.0250

0 10 20 30 40 50 60 70

Ra

tio

NP

L/H

os

t

Audit number

Machine output (cGy/MU)

NPL/Host 1.003 std dev 0.7%

Nisbet/Host 1.003 std dev 1.0%

Thwaites/Host 1.003 std dev 1.5%

Electron 2003 C of P

Depth dose measurements in water

Electron 2003 C of P

measurements in solid water

Electrons 2003

C of P

0.994

0.996

0.998

1

1.002

1.004

1.006

1.008

1.01

1.012

1.014

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Machine output

NPL/Host 1.003 std dev 0.3%

Nisbet/Host 0.994 std dev 1.8%

NPL/Host 1.003 std dev 0.4%

0.996

0.998

1

1.002

1.004

1.006

1.008

1.01

1.012

1.014

0 1 2 3 4 5 6 7 8

Rati

o N

PL

/Ho

st

Audit number

Field instrument

kV set up for HVL

measurements

kV audit results

0.85

0.9

0.95

1

1.05

1.1

1.15

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Beam Quality

NPL/Host

1.018

std dev 4.7%

kV audit results

0.96

0.97

0.98

0.99

1

1.01

1.02

1.03

1.04

1.05

0 1 2 3 4 5 6 7 8

Ra

tio

NP

L/H

os

t

Audit number

Machine output

Machine output

expected

NPL/Host 1.002 std dev 0.8% NPL/Host 1.002 std dev 0.6%

0.96

0.97

0.98

0.99

1

1.01

1.02

1.03

1.04

1.05

0 1 2 3 4 5 6 7 8

Rati

o N

PL

/Ho

st

Audit number

Field Instrument

(1.5%)

A review of NPL audit

or

What are we actually

trying to achieve?

Russell Thomas

Radiation Dosimetry Group,

National Physical Laboratory

NPL is usually about uncertainty to 1 part in

so many million

“NPL's atomic clock revealed to

be the world's most accurate”

"Together with other improvements of the caesium

fountain, these models and numerical calculations

have improved the accuracy of the UK's caesium

fountain clock, NPL-CsF2, by reducing the

uncertainty to 2.3 × 10-16 - the lowest value for any

primary national standard so far."

Monday, 13 January 2014

21

• ICRU 24 - Dose delivery to the primary

target should be within +/- 5% of the

prescribed value (some literature is quoting

that this should be within +/- 2%)

Monday, 13 January 2014

22

• ICRU 24 - Dose delivery to the primary

target should be within +/- 5% of the

prescribed value (some literature is quoting

that this should be within +/- 2%)

• Uncertainty on the NPL calibration of the

Secondary Standard 2611 chamber is

+/-1.5%

Monday, 13 January 2014

23

UK Codes of Practice Monday, 13 January 2014

24

What are WE trying to achieve? Is it :-

• Just not getting caught with our pants down

• Delivering a “legal” dose

• Are we fulfilling a tick box exercise? ie

traceability and audit – done!

Monday, 13 January 2014

25

What are WE trying to achieve? Is it :-

• Just not getting caught with our pants down

• Delivering a “legal” dose

• Are we fulfilling a tick box exercise? ie

traceability and audit – done!

or

• Are we aiming for best practice and treatment

• As tight a consistency of dose delivered to

individuals across a patient population

Monday, 13 January 2014

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A statement made to me by a clinical

oncologist -

“Accurate dosimetry is not that important”

Monday, 13 January 2014

27

A statement made to me by a clinical

oncologist -

“Accurate dosimetry is not that important”

….but if you can’t get your reference

dosimetry right, no complex treatment you

deliver will be “correct”.

Monday, 13 January 2014

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• In my view audit, and indeed reference

dosimetry audit, is a crucial component in

the provision of the complex radiotherapy

that is, and will become, available with

current and future technology.

Monday, 13 January 2014

29

But there are issues:-

• Hidden costs

Monday, 13 January 2014

30

But there are issues:-

• Hidden costs

• Pressure on staff time

• People feel over audited

• Value and benefit

• Regulation

• Lack of senior management understanding

Monday, 13 January 2014

31

Monday, 13 January 2014

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Thank you, questions?