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DIAGNOSIS AND TREATMENTOF

CHANCROID

Reski Harlianty Harli

Prajogo Kusua

A!"isor#!r$ Fau%an

Su&er"isor#Dr$ !r$ Sis'anto (a)a*+ S&$ KK

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De,nition

A se-ually transitte! a.ute ul.erati"e !isease lo.ali%e! at t)e anogenital area an! o/ten asso.'it) inguinal a!enitis or *u*o$

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E&i!eiology

More re.ent re&orts /ro Sout)east Asia an! A/rsuggest t)at t)e in.i!en.e o/ .)an.roi! ay *e!e.lining in t)e /a.e o/ a ra&i!ly rising in.i!en.egenital )er&es$ T)e &re"alen.e o/ .)an.roi! is )lo'er so.ioe.onoi. grou&s$ Re.ent e&i!ei.s iin!ustriali%e! .ountries )a"e usually *een asso.'it) .oer.ial se- 'ork+ t)e use o/ .ra.k .o.a'it) sy&)ilis an! an in.rease! risk o/ HI0 in/e.tio.ases o/ .)an.roi! 'ere re&orte! to t)e CentersDisease Control an! Pre"ention 3CDC4 in 1556$

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Etiology

Haemophilus ducreyi7a Gra8negati"e+ /a.ultaanaero*i. .o..o*a.illus7is t)e .ausati"e agent$

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Clini.al Mani/estation

Pain/ul+ so/t ul.ers 'it) ragge! un!erine! ar!e"elo& 9:1 'eeks a/ter ino.ulation 3usually &rean! /renulu in en an! "ul"a+ .er"i-+ an! &eriarea in 'oen4$

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C)an.roi!al ul.eration o/ t)e &'it) !is.)arging inguinal *u*o

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Diagnosis

Gra Staining Gra stain suggesti"e o/ Haeo&)ilus !u.reyi 3gra

negati"e+ slen!er ro! or .o..o*a.illus in a ;s.)ool o/ &attern4

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Haeo&)illus !u.reyi .ulture Multiplex Polymerase Chain Reaction3M8PCR4

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Di=erential Diagnosis

Her&es Genitalis Si,lis

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Treatent

Nee!le as&iration o/ >u.tuant *u*oes A%it)roy.in+ 9 g orally in a single !ose

Ce/tria-one 1?5 g intraus.ularly in a single !

Ci&ro>o-a.in?55 g orally t'i.e !aily /or t)ree

Eryt)roy.in+ ?55 g orally /our ties !aily /or !ays

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Prognosis

T)e !isease is sel/8liite! an! systei. s&rea! !oo..ur$ O..asionally+ 'it)out treatent+ genital ul.inguinal a*s.ess )a"e *een re&orte! to &ersist /o

I/ no .lini.al i&ro"eent is e"i!ent 9 'eek a/testart o/ t)era&y+ in.orre.t !iagnosis+ .oin/e.tion 'anot)er STI+ .on.oitant HI0 in/e.tion+ &oor .oor a resistant strain o/ H. ducreyi ust *e .onsi!e

In/e.tions !o not .on/er iunity an! rein/e.tion&ossi*le$ To a"oi! rein/e.tions+ &atients ust *einstru.te! to use .on!os &ro&erly$

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THANK

YOU

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