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Sixth Meeting of the Working Group on MDR-TB of the Stop Tb Partnership
20 – 22 September 2007
Tbilisi, Georgia
Lessons learned about the management of
second-line anti-TB drugs
Jaime Bayona, MD, MPH (PERU)
Health Promoters = 10 Patients = 14Health Promoters = 10 Patients = 14
Expanding the Community-Based
MDR-TB Care Model
Year 1996: Carabayllo (Northern Lima)
Expanding the
Community-Based MDR-TB Care Model
Year 2007: 12 Regions
• Piura
• Lambayeque
• La Libertad
• Ancash
• Lima y Callao
• Junín
• Ica
• Arequipa
Health Promoters = 700 Patients > 6,000Health Promoters = 700 Patients > 6,000
Lesson # 1: Political will
Global Fund & NTPNTP√2006
Global FundNTP√2005
Global FundNTP√2004
Gates FoundationNTP√2003
Gates FoundationNTP√2002
Gates FoundationNTP√2001
Private donorsNTP98-00
Private donorsNTP1997
Private donors1996
ITRSTR
Source of fundingGLCYear
Fuente: Estrategia Sanitaria Nacional de Prevención y Control de la Tuberculosis-DGSP/MINSA
NTP Peru’s budget: Years 1991-2006
0
2
4
6
8
10
12
1991 1992 1993 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006
Average budget during 1991- 2005:
3 000,000 USD
Millones $ USD
9 780,000 USD
Change of leadershipHigh turnover of staffHealth Sector Reform
133
813 12
2
36
0
20
40
60
80
100
120
140
Dr PS Dr RA Dr ET Dr RC Dr DZ Dr CB
Months
Adapted from Revista de la Sociedad Peruana de Neumologia Vol 48-N°1 – En-Abr 2004
Lesson # 2:
Uninterrupted access to good quality 2nd line anti-TB drugs
is a constant challenge
Donor(s)
&
local
representative
of donor
Lesson # 3: Managerial support useful at the start, with the plan of transferring
responsibility to NTP
• Selection of the regimen (STR or ITR or empiric)
• Process of purchasing
• Distribution
• Use of the MDR TB meds
Donor(s)&
local
representative
of the donor
Lesson # 4: Promote expanding partnerships while maintaining state leadership
PARTNERS TB CONTROLWHO/PAHOPIH/SESHARVARD
MSLICDC
TASK FORCE
Lesson # 5: The process of ordering the drugs needs to be improved
Donor
&
Principal
Recipient
GLC approval date Request for quote6 m
Request for ordering3 m
Meds delivery
6 m
Lesson # 6: The quality of the medicines purchased outside GLC is unknown and uncertain
• Shortage of meds: CM, PAS, CS
• Short shelf life
• Cold chain (PASER)
• Modification of regimen
• Enrollment process/ordering
• Change in duration of treatment
Lesson # 7: Several constraints need to be resolved
Lesson # 8: It is important to have a warehouse with Good Storage Practices in place
Lesson # 9: Technical assistance should be also uninterrupted
Lesson # 10: Sharing experiences enriches all parties involved
Thank you very much!
¡Muchas gracias!