Setting Up a Research Setting Up a Research Review BoardReview Board

Ralph E. PaganoRalph E. Pagano

Research DirectorResearch Director

Hoosic Valley High SchoolHoosic Valley High School

Why Are Research Review Why Are Research Review Boards Necessary?Boards Necessary?

Federal LawFederal Law– If an insitution uses Federal $ it is required.If an insitution uses Federal $ it is required.

CompetitionsCompetitions– Most competitions such as Intel and Science Most competitions such as Intel and Science

& Engineering Fair require projects to be & Engineering Fair require projects to be review board approved.review board approved.

SafeguardSafeguard

Purpose of Review Purpose of Review CommitteesCommittees

NOT to advise!NOT to advise! Must review proposal as written as to risks Must review proposal as written as to risks

posed to subjects involved in research or posed to subjects involved in research or to the researcher.to the researcher.

Primary focus is on whether or not safety Primary focus is on whether or not safety and risk factors have been dealt with and risk factors have been dealt with appropriately. appropriately.

Types of Review CommitteesTypes of Review Committees

INSTITUTIONAL REVIEW BOARDS (IRB)INSTITUTIONAL REVIEW BOARDS (IRB)– Reviews research involving human subjects.Reviews research involving human subjects.

INSTITUTIONAL ANIMAL CARE AND USE INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC)COMMITTEE (IACUC)– Reviews research involving vertebrate subjects other Reviews research involving vertebrate subjects other

than humans.than humans. SCIENTIFIC REVIEW COMMITTEE (SRC)SCIENTIFIC REVIEW COMMITTEE (SRC)

– Reviews all research not covered by the above two Reviews all research not covered by the above two including research that puts researcher alone at risk. including research that puts researcher alone at risk.

Local vs. Regional Review Local vs. Regional Review CommitteesCommittees

RegionalRegional– EstablishedEstablished

– ““Professional”Professional”

LocalLocal– Easier accessEasier access

– Less travel & Less travel & coordinationcoordination

– Ownership within Ownership within districtdistrict

Role of Various Parties Role of Various Parties InvolvedInvolved

Research TeacherResearch Teacher– Be familiar with student’s research and methods.Be familiar with student’s research and methods.

– Be familiar with all pertinent regulations regarding that research.Be familiar with all pertinent regulations regarding that research.

MentorMentor– Oversee student’s research proposal.Oversee student’s research proposal.

– Be knowledgeable of all pertinent regulations regarding that Be knowledgeable of all pertinent regulations regarding that research.research.

Student ResearcherStudent Researcher– Write a detailed research proposal taking into account all safety Write a detailed research proposal taking into account all safety

procedures and regulations governing that research.procedures and regulations governing that research.

Committee Make-UpCommittee Make-Up

AdministratorAdministrator Science TeacherScience Teacher One or more Biomedical Professionals (Nurse, One or more Biomedical Professionals (Nurse,

Doctor, Psychologist, Veterinarian)Doctor, Psychologist, Veterinarian) One or more Community MembersOne or more Community Members

Running a Committee Running a Committee MeetingMeeting

Appoint chairperson (signature required)Appoint chairperson (signature required) Research Teacher can act as secretary to Research Teacher can act as secretary to

keep noteskeep notes Members sign off on final approvalMembers sign off on final approval

FormsForms

Human SubjectsHuman Subjects– ApprovalApproval– Informed ConsentInformed Consent

Vertebrates Other Than HumansVertebrates Other Than Humans– ApprovalApproval– Risks to SubjectsRisks to Subjects

Scientific ReviewScientific Review– ApprovalApproval– Risks and SafetyRisks and Safety

Any Questions?Any Questions?