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Serratiopeptidase is an enzyme having anti-inflammatory, anti-oedemic and fibrinolytic activity and it also acts rapidly

on localized inflammation. Serratiopeptidase has been widely used in the treatment of acute pain.

Functioning of Serratiopeptidase

The drug works by improving aggravated circulation in the inflammatory focus by breaking down abnormal exudates

and protein by promoting the absorption of the decomposed products through the blood and lymphatic vessels.

Serratiopeptidase tablets also help the elimination of sputum, pus and haematoma. This they do by breaking down

the liquefying mucus secretions and fibrin clots. Another major useful action being increased concentration of

antibiotics in the focus of infection.

Serratiopeptidase Popular Names

This drug is referred by several names like Serralysin, serratia peptidase, serratiapeptase, serratio peptidase, or

serrapeptidase

Serratiopeptidase Tablets Use

Serratiapeptase is used in the treatment of Chronic inflammation, the cause of which lies on a number of ailments like

as follows:

  Headaches, muscle and joint pain

  Serious diseases like cancer and heart disease

  Back pain

  Superficial thrombophlebitis

  Postoperative & traumatic swelling

  Acute or chronic ear, nose or throat disorder

It is to be noted that while most pain medicines only relieve the inflammation, serratiopeptidase tablets actually help

in breaking down the protein deposits (fibrin) which continues to cause pain and discomfort, even when the body is

healed from an injury or other irritation.

Dosage of Serratiopeptidase

5-10 mg thrice a day after meals

Side Effects of Serratiapeptase

The drug has certain side effects, that can affect individuals in different ways. The following are some of the side

effects, that are often associated with the drug:

  Anorexia

  Gastric Discomfort

  Nausea 

Discontinue use of hypersensitive symptoms such as eruptions appear. The drug should be used with caution by

pregnant and lactating women.

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Nimesulide is a popular NSAID and available in various forms including tablets, suppositories, water-soluble powders,

and topical gels.

It is an analgesic and antipyretic in action, apart from its anti inflammatory action. Unlike, other NSAIDs, the chemical

structure of nimesulide does not contain a carboxylic group but a sulfonanilide moiety as the acidic group. It is

absorbed rapidly and completely after oral administration.

Brand Name: Ainex, Aulin, Donulide, Edrigyl, Eskaflam, Heugan, Lusemin

Working 

It acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release

and reduces superoxide anion formation

Dosage 

Adults: 100 mg twice daily

Children: 5mg/kg of body weight in 2 or 3 divided doses.

Contra- Indications: Hypersensitivity, active peptic ulcer disease, hepatic impairment

Side Effects The drug has certain side effects, that can affect individuals in different ways. The following are some of the side

effects, that are often associated with the drug:

  Diarrhoea

  Vomiting

  Skin rash

  Pruritis

  Dizziness

  Headache

Women should use the drug with caution during lactation and it is contraindicated during pregnancy.

COMMON TABLETS:-

Amlodipine Besylate 

- Ambroxol 

- Aciclovir 

- Atorvastatin 

- Atenolol 

- Azithromycin 

- Allopurinol

- Bisacodyl 

- Cyproheptadine 

- Cefuroxime Axetil 

- Cefixime - Cetrizine Hydrochloride 

- Ciprofloxacin 

- Cephalexin

- Cetrizine Hydrochloride 

- Chloroquine 

- Diclofenac 

- Domperidone 

- Enalapril Maleate 

- Erythromycin Estolate 

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- Ethamsylate 

- Fexofenadine 

- Fluconazole -Gliclazide 

- Glipizide 

- Glibenclamide 

- Gatifloxacin 

- Hyosine Butyl Bromide - Isosorbide Mononitrate 

- Ketoconazole 

- Losartan Potassium 

- Lovastatin 

- Levofloxacin 

- Lisinopril (Anhydrous)

- Loratidine 

- Levocetrizine 

- Levamisole Hydrochloride 

- Mecobalamin 

- Metformin Hydrochloride 

- Metformin Hydrochloride 

- Metocloperamide - Norethindrone Acetate 

- Nimesulide 

- Ofloxacin 

- Piroxicam 

- Pantoprazole 

- Paracetamol 

- Prazosin 

- Piroxicam 

- Roxithromycin 

- Ramipril 

- Roxithromycin 

- Sildenafil Citrate 

- Secnidazole - Serratiopeptiadase 

- Tadalafil 

- Tinidazole 

Side Effects 

The drug has certain side effects, that can affect individuals in different ways. The following are some of the side

effects, that are often associated with the drug:

  Diarrhoea

  Vomiting

  Skin rash

  Pruritis  Dizziness

  Headache

Women should use the drug with caution during lactation and it is contraindicated during pregnancy. 

ANTI HISTAMINES

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20 Dec 2010 Antihistamines are commonly used tables for treating allergic  symptoms like rash, hives, hay fever,

runny nose, watery eyes, itching, and sneezing etc. These are allergies or the common cold problems faced by many

and most anti histamine drugs  can be purchased over the counter . These tablets can also used to treat motion

sickness, anxiety, or as a sleep aid (for insomnia).

How to Use Anti Histamines?

The tablets are needed to be taken with milk or food if there is   stomach  upset

problem. It is also recommended to take the capsule as a whole instead of

chewing or crushing the tablet because crushing will destroy the long action and

may increase side effects. For chewable antihistamine tablets, chew thoroughly

and swallow. For liquid syrup, shake it well before taking.

Side Effects of Anti Histamine Tablets

Certain side effects are common while consuming such tablets like as drowsiness,

headache, dizziness, loss of appetite, stomach upset, irritability, vision changes,

dry mouth and nose. As the body adjusts to the medication, these effects subside.

For other problems like breathing difficulties, pounding or irregular heartbeat,

difficulty urinating, ringing in the ears, consult your doctor.

Precautions using Anti Histamines

Before consuming anti histamine tablets, give an idea to your doctor about your medical history, especially if you had

faced problems earlier like glaucoma (narrow angle), enlarged prostate, stomach ulcers, heart disease, seizures, lung

problems, high blood pressure, overactive thyroid. While taking the medicine, change from a seated or lying position

to avoid dizziness. Be careful in doing activities requiring alertness. For instance, you should never drive after taking

an anti histamine tablet. Limit alcohol intake to avoid drowsiness. Elderly persons should be very careful while

consuming antihistamines as they are more sensitive to the effects of the drug. Do not give long-acting antihistamines

to a child younger than 6 years of age without doctor approval. This drug should not be used during pregnancy.

Consult your doctor before breast-feeding.

Antihistamines Interactions with Other Drugs

Your doctor should have knowledge of all the other medications you may use (both prescription and nonprescription),

like sleeping pills, tranquilizers, sedatives, muscle relaxants, depression medication, narcotic pain relievers, seizure

medications, other medications for hay fever, colds or allergies. Because this medication may affect allergy testing,

you have to stop using this medication for few days before the tests are performed. Though this medicine can be

purchased without a doctor's prescription, it is better to take the doctor or pharmacist approval.

Symptoms of Overdose in children

  Abnormal eye movements

  Dry mouth

  Flushed face

  Change in amount of urine

  Fever

  Bizarre behavior

  Agitation

  Restlessness

  Confusion

  Irritability

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  Abnormal tongue movement etc.

Missed Dose

If you miss a dose, take as soon as you remembered and if it is almost at the same time for the next dose, then it is

better to skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

SCIATICA DRUGS

Cloxil Capsules & Injections

ampicillin and cloxacillin 250mg, 500mg capsules &

250mg, 500mg & ds (1gm) i. M. & i. V. Injection

Send Enquiry

Fortral-Plus

Muscle Relaxant & Analgesic Ointment 25gms.

Description: 

Slightly translucent, off white coloured water soluble ointment (gel) with characteristic odour.

Composition: 

Diclofenac Diethylammonium 1.16% w/w

Mephenesin Sulphate I.P. 5.0 % w/w

Methyl Nicotinate B.P. 1.0 % w/w

Chlorpheniramine Maleate I.P. 0.2 % w/w

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Turpentine Oil B.P. 3.0 % w/w

Menthol I.P. 2.0 % w/w

Methyl Salicylate I.P. 5.0% w/w

Ointment Base q.s.

Send Enquiry

Amcil-A Injection

100M,g/250mg/500mg Injection (I.M. & I.V. use) 

AMCIL-A (Amikacin injection 100mg/2mL; 250mg/2mL; 500mg/2mL)

Description

AMCIL-A (Amikacin) is a semisynthetic aminoglycoside antibiotic derived from kanamycin. Amikacin occurs as a

white, crystalline powder and is sparingly soluble in water. The injection consists of the sulphate salt. The molecular

formula is C22H47N5O21S2 .

AMCIL-A Injection is a sterile clear, colourless solution, free from specks, lint, or other visible evidence of

contamination. Each 2 mL vial contains amikacin sulphate equivalent to amikacin activity 100/250/500 mg (1/2.5/5 x

100,000 I.U.). The vial also contains Sodium Citrate I.P. and Sodium Metabisulfite I.P and suitable preservatives.

Send Enquiry

Amcil-T Injections

AMCIL-T INJECTION is a third generation cephalosporin antibiotic. It has a very broad spectrum of bactericidal

activity. AMCIL-T INJECTION contains Sterile Cefotaxime Sodium I.P. equivalent to 250 mg / 500 mg / 1 gm of

anhydrous Cefotaxime in each vial. It is provided in a combi-pack along with Sterile Water for Injection I.P.

Send Enquiry

Ampicillin Injection

100mg/250mg/500mg/1gm 

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Send Enquiry

Fortral-Kt Tablet

FORTRAL-KT (Ketorolac), a pyrrolizine carboxylic acid derivative structurally related to indomethacin. It is a non-

narcotic, non-steroidal anti-inflammatory drug used principally for its pronounced analgesic activity . It is used

intramuscularly, intravenously, or orally as the salt in the short-term management of moderate to severe pain in :-

(1) Post operative pains after Major surgery, abdominal surgery, gynaecological surgery, orthopaedic surgery etc.

(2) Acute musculoskeletal painful conditions like acute strain and sprain, dislocation, fracture and soft tissue injury.

(3) Dental pain including pain after oral surgery.

(4) Cancer pain , sciatica, chronic pain states, and as an adjuvant in renal colic and biliary colic.

Send Enquiry

Metabolin / Depot Injection (Nandrolone)

METABOLIN & METABOLIN DEPOT are anabolic steroids having higher anabolic and lower androgenic activity.

Their effects are similar to testosterone. METABOLIN contains Nandrolone Phenylpropionate 25 mg per 1 ml.

ampoule and METABOLIN DEPOT contains Nandrolone Decanoate 25 mg per 1 ml. ampoule.

USES : METABOLIN & METABOLIN DEPOT tend to increase retention of nitrogen, calcium, sodium, potassium, chloride

and phosphate leading to an increase in skeletal weight, water retention and increased growth of bone. A nourishing

diet should be accompanied with METABOLIN & METABOLIN DEPOT therapy for increased body protein and body

weight.

INDICATIONS : 

METABOLIN & METABOLIN DEPOT are indicated in Osteoporosis, Chronic debilitating diseases to correct

defective protein metabolism, after surgery, burns , major illness, in Suboptimal growth in children, to counteract

glucocorticoid, in Hypoplastic, Haemolytic or malignancy associated anaemia.

LIGAMENT TEAR OF THUMB

Gamekeeper's Thumb

What is the ulnar collateral ligament?

By Jonathan Cluett, M.D., About.com Guide

Updated December 06, 2009

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 About.com Health's Disease and Condition content is reviewed by the Medical Review Board  

See More About: 

  thumb sprains 

  finger injuries 

  trigger finger 

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The ulnar collateral ligament is a band of tough, fibrous tissue that connects the bones at the base of 

the thumb. This ligament prevents the thumb from pointing too far away from the hand.

How is the ulnar collateral ligament injured? 

Two common descriptive terms for injuries to the ulnar collateral ligament are:

  "skier's thumb" and

  "gamekeeper's thumb"

These eponyms are often used interchangeably, although they describe slightly different injury

patterns.

The skier's thumb injury was described as an acute injury to the ulnar collateral ligament. When a

skier falls with his or her hand caught in a ski pole, the thumb can be pulled away from the hand.

Because of the shape of the ski pole, the thumb tends to get caught and significant stresses are

placed on the ulnar collateral ligament. If the ulnar collateral ligament is pulled far enough, it will tear.

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While there are many ways to injure the ulnar collateral ligament, a skier's thumb is the proper

eponym for an acute injury to the ligament.

The other injury is called a gamekeeper's thumb; this refers to a more chronic pattern of injury 

that leads to loosening of the ulnar ligament over time. The name comes from the European

gamekeepers who would kill their game by grasping the head of the animal between their thumb and

index finger to break its neck. Over time, the ulnar collateral ligament is stretched and would

eventually cause problems. Again, gamekeeper's thumb is the proper eponym to describe chronic

injuries to the ulnar collateral ligament.

An ulnar collateral ligament injury most often occurs as a result of sports injuries. Athletes who are

skiers and soccer players often sustain this injury. An ulnar collateral ligament injury can also occur as

the result of a fall or other trauma.

What are common symptoms of an ulnar collateral ligament injury? 

Patients who sustain an acute tear of the ulnar collateral ligament typically complain of pain and

swelling directly over the torn ligament at the base of the thumb. Patients will often have a difficult

time grasping objects or holding objects firmly in their grip. Because this injury is commonly seen in

athletes, they will often complain of difficulty holding a tennis racket or throwing a baseball. Patients

may also complain of instability or catching their thumb in pockets of their pants.

What is the treatment for an ulnar collateral ligament injury? 

The treatment depends on several factors, including the extent of the injury, how long ago the injury

occurred, the age of the patient, and the physical demands of the patient. If the tear is partial, and

the thumb is not too loose, the patient is usually placed in a cast or a modified wrist splint (called a

thumb spica) for 4 to 6 weeks.

If the tear is complete or if the patient has significant instability due to the tear of the ulnar collateral

ligament, then surgery may be considered. Surgery is usually most effective when performed withinthe first few weeks following injury. If possible, the surgeon will repair the torn ends of the ligament

back together. If the ligament is torn from the bone, then the torn end will be sutured down to the

bone itself.

If the injury to the ulnar collateral ligament is older, then it is likely that a direct repair will not be

possible. In this case, either another structure will be transferred to reconstruct the ulnar collateral

ligament or one of the muscles at the base of the thumb will be advanced to compensate for the torn

ligament.

What is the recovery after ulnar collateral ligament repair? 

Following surgery, patients will be placed in a cast for four to six weeks to protect the repairedligament. At that point, gentle motion of the finger will begin. Most patients are able to play sports 3

to 4 months after surgery.

Sources:

Morgan WJ, Slowman LS. "Acute hand and wrist injuries in athletes: evaluation and management." J Am Acad Orthop Surg. 2001 Nov-Dec;9(6):389-400.

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Other Hand Conditions

  Trigger Finger 

  Carpal Tunnel Syndrome 

  Ganglion Cyst 

Treatment Help

  Find A Doctor 

  Ice an Injury 

Related Articles

  Ligament Injuries of the Knee 

  MCL Tear - Medial Collateral ligament Injury 

  Medial and Lateral Collateral Ligament Injuries 

  Knee Sprain 

  Knee Pain Symptoms - Instability - Giving Out 

Sprained Thumb 

Scenario:Rounding a corner on the South Mountain race loop, your tires begin to dig into the soft

shoulder. For a second, you think you're going to pull it out. But then the bike flips sideways,

and you're flying off the trail. As you catch yourself, your thumb hangs up in the soft dirt and

bends down towards your wrist.

Description:

A sprain is a stretching of ligaments -- the tissues that hold two bones together. In the thumb, you

have these ligaments on the inner and outer sides of each joint, and on the underside of each

 joint. When an accident bends the joint in a direction it's not supposed to go (most commonly,

bending backwards), it injures the ligament. Ligament injuries come in three degrees of 

seriousness: 1st degree = stretching, 2nd degree = partial tear, and 3rd degree = completerupture.

If the spraining force bends the thumb straight back (in the direction of the thumbnail), the sprain

usually won't be serious. But it forces the thumb laterally downward (force on the side of the

thumb that faces the index finger, pulling it down towards the wrist), it can rupture the ulnar

collateral ligament, making the thumb unstable.

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Concerns:

A rupture of the ulnar collateral ligament (located on the side of the thumb right where it meets

the skin fold coming over from the index finger) is serious. Of course, the same forces that sprain

a thumb can also cause dislocation, tendon rupture, fracture, or volar plate injury. So you should

assess careful for the signs of serious injury. Only if the injury seems trivial should you self-

diagnose a sprain.

See the doctor for an injured finger if:

there's significant swelling or deformity

there's pain when the thumb is resting (after the first hour)

you can't move the joint fully

there's severe pain with motion of the thumb

there's numbness or weakness

there's weakness at the base of the thumb with pinching motion

the thumb can be bent outward at either knuckle

Immediate care:Rest, Ice, Compress, and Elevate. Immediately elevate the injured part and apply an ice bag. If 

the distant knuckle is injured, splint it. If the pain is at the first knuckle, you'll probably need to

see the doctor for adequate splinting. (And maybe an x-ray.)

To assess the ulnar collateral ligament (UCL), have the

injured thumb straight and out away from the hand. Put

your index finger pad on the side of the thumb that faces

the hand, right at the end. Put the tip of your good thumb

right up against the other side of the thumb

metacarpophalangeal joint (first knuckle or MCPJ).

 Location of tenderness and swelling in ulnar collateral ligament 

injury. 

While bracing the MCPJ of the injured thumb with your

thumbtip, pull down with your index finger. If the thumb

can be bent downward more than about a half-inch, the

UCL is probably ruptured. See the doc.

Stress test for ruptured ulnar collateral ligament: pulling downward 

on the side of the thumb while bracing the MCPJ with the thumbtip. 

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Ongoing care:

For the first 48 hours, repeat ice and elevation 1/4 of the time (for example, 30 minutes of ice

every two hours). Continue splinting for a few days. As the pain subsides, return to activities.

Often you can protect the injured finger by "buddy taping," taping it to an adjacent bigger

stronger finger. It will take about three weeks for the sprain to heal. As you resume sports,

remember the rule: "If it hurts, don't do it." If the finger becomes increasingly swollen, orremains weak or painful in routine use, go to the doctor.

Finger rehab:

After the first few days of splinting, start range of motion exercises.

Range of motion: Warm the finger for 10 minutes (heating pad or sink of warm water). Gently

bend the finger until it begins to feel uncomfortable, then hold the stretch for 30 seconds. Rest

for a minute, then do it again. Repeat 10 times. Now straighten the finger and hold for 30

seconds, rest a minute, and repeat 10 times. If the finger has increased discomfort after the

exercises, ice the wrist for 20 minutes after the exercises. Do the exercises twice a day.

Watch for:If the injured area doesn't improve promptly, see the doctor.