SEMESTER VIII PHARMACOGNOSY-VI (2280005) Multiple Choice

Ms. H. S. Popaniya, Assistant Professor, Page 1 Faculty of Pharmacy, Dr. Subhash Technical Campus, Junagadh

SEMESTER VIII

PHARMACOGNOSY-VI

(2280005)

Multiple Choice Questions

PHARMACOGNOSY-VI (2280005)

Faculty of Pharmacy, Dr. Subhash Technical Campus, Junagadh Page 2

1. What is Aim of Pharmacovigilance?

A. To improve patient care & safety in relation to medicines & all medical & para-medical

interventions

B. To improve public health & safety in relation to the use of medicines

C. To contribute to the assessment of benefit, harm, effectiveness and risk of medicines

D. All of Above

Ans: A

2. Some unwanted reactions in pharmacovigilence study due to herbs can be

A. Usually not detectable by pharmacodynamics and often predictable

B. Detectable either by pharmacodynamics or pharmacovigilance

C. No Hypersensitivity, no allergic and no idiosyncratic reactions

D. No any Mid-term and long-term toxic effects including liver, renal, cardiac and neurotoxicity also

Ans: C

3. Which Classifications of Adverse drug reaction are incorrect?

A. Type A-Augmented

B. Type B-Idiobratic

C. Type C-Cumulative

D. Type D-Delayed Onset

Ans: B

4. The general techniques of medicinal plant extraction are

A. Infusion

B. Digestion

C. Counter-current extraction

D. All of above

Ans: D

5. Which is not include in Extraction techniques For aromatic plants

A. Headspace trapping

B. Microdistillation

C. Phytonic extraction

D. Hydrodistillation techniques

Ans: D

6. Which method is best suitable for use in case of the thermolabile drugs

A. Decoction

B. Maceration

C. Digestion

D. Hot Continuous extraction

Ans: B



7. Which criteria are not match to the percolation method

A. Continuous flow of solvent through the bed

B. In this process, the crude drug is boiled in a specified volume of water

C. The solid ingredients are moistened with an appropriate amount of the specified menstruum

D. The mixture is allowed to macerate in the closed V shaped percolator for 24 h

Ans: B

8. Ultrasound with frequencies ranging from

A. -30 kHz to 3000 kHz

B. 20 kHz to 2000 kHz

C. 1-0 kHz to 1000 kHz

D. 40 kHz to 4000 kHz

Ans: B

9. Chromatography can not be classified according to mechanism of separation as

A. Absorption chromatography

B. Partition chromatography

C. Ion exchange chromatography

D. All of abobe

Ans: D

10. Modern (Non-traditional) Methods of Extraction are

A. Solid phase micro-extraction (SPME)

B. Supercritical fluid extraction (SFE)

C. Simultaneous distillation extraction (SDE)

D. All of Above

Ans: D

11. Which chemical is not used in estimation of sennoside?

A. HCl

B. KOH

C. NaCl

D. Ether

Ans: C

12. Which is biological source of Dioscoria ?

A. Dioscorea Deltoidea

B. Dioscorea Tokora

C. Above A and B

D. Dioscorea is obtained from Discoreac officinalis

Ans: A



13. Rutin is used in

A. antioxidant

B. Oedema

C. Anti-inflammatory

D. All of Above

Ans: D

14. Which method is not used for Estimation of caffeine?

A. HPLC

B. Mass Spectroscopy

C. HPTLC

D. Potentiometry

Ans: A

15. Which colour is obtained in Dragendroff reagent with alkaloid?

A. Orange red ppt

B. Cream colour ppt

C. Yellow ppt

D. Purple colour

Ans: A

16. Which method is not used for evaluation of volatile oil containing drugs?

A. Noller test

B. Salkowski test

C. Antimony trichloride

D. All of Above

Ans: D

17. Which Precaution taken against contamination and mixing of herbal drugs in manufacturing?

A. Not required exhaust system

B. Using appropriate pressure differential in the process area

C. Expert technical staff are not required

D. all of above

Ans: B

18. The manufacturing plant should have adequate space for

A. Manufacturing process area

B. Quality control section area

C. Finished good store

D. All of Above

Ans: D



19. Which drug is not used in memory enhancer?

A. Galo

B. Brahmi

C. Ginseng

D. Ephedra

Ans: A

20. Which drug is used in hepatoprotective drug?

A. Garcenia

B. Amla

C. Vinca

D. Lobelia

Ans: B

21. Which qualitative methods used for alkaloids?

A. Mayer’s test

B. Wagner’s test

C. Dragendroff’s test

D. All of above

Ans: D

22. What are the charecteristics of volatile oil

A. Strong odour and smell

B. Do not leave permanent grease spot

C. Solid form

D. a and b

Ans: D

23. Alkaloid react with HNO3 and brucine give

A. Red colour

B. Yellow colour

C. Orange colour

D. Pink colour

Ans: B

24. Antimony trichloride test is used for

A. Tannin

B. Alkaloid

C. Glycoside

D. All of above

Ans: D



25. Which method are used for Qualitative analysis?

A. HPLC

B. HPTLC

C. Colum chromatography

D. all of above

Ans: D

26. Which method are used for preparation of herbal extract?

A. Sublimation

B. Digestion

C. HPLC

D. a and b

Ans: D

27. What is the disadvantage of ultrasonic extraction

A. formation of free radicle

B. low cost

C. less time

D. all of above

Ans: A

28. which parameter are affect to super critical fluid extraction method

A. pressure

B. density

C. temperature

D. a and c

Ans: D

29. Estimation of Embelica officinalis by

A. vitali morine test

B. Total phenolic content

C. TLC

D. all of above

Ans: B

30. which constituent are preseant in Allium sativum

A. Allin

B. allyl propyl amine

C. diallyl tri sulphate

D. all of above

Ans: A



31. what is biological source of Garcenia

A. Garcina alba

B. Garcinia cambogia

C. Garcinia officinalis

D. all of above

Ans: B

32. which parts are involved in preparation of Alium sativum?

A. bulb of garlic

B. dried peel of cloves of garlic

C. powder of leaves of garlic

D. all of above

Ans: B

33. which parameter are used for evaluation of herbal drugs?

A. Viscosity

B. melting point

C. Solubility

D. all of above

Ans: D

34. Gas Chromatography depend on

A. Adsorption

B. Absorption

C. differential migration

D. all of above

Ans: C

35. what is the principal of HPTLC?

A. adsorption

B. partition

C. absorption

D. a and b

Ans: D

36. Which drug is used for reduce production of fat?

A. Amla

B. Garcenia

C. Aswagandha

D. all of above

Ans:B

37. what is family of Garcenia?

A. Guttiferae

B. apoyneceae



C. Rubiaceae

D. leguminoseae

Ans: A

38. what is basic requirement of hot contineous extraction method?

A. thimble

B. condenser

C. filter paper

D. all of above

Ans: D

39. Microwave assisted extraction method are

A. energy vector

B. electromagnetic energy

C. a and b

D. preparation of antibodied

Ans: C

40. which method is used for evaluation of alkaloid?

A. wagner's method

B. balget test

C. legal test

D. killer killiani test

Ans: A

41. Evaluation of drugs include

A. Microscopy

B. Macroscopy

C. Chemical reaction

D. All

Ans: D

42. Microbial toxins includes

A. Mycotoxins

B. Endotoxins

C. Both a and b

D. None

Ans: C

43. Full form of ADI is

A. Acceptable diet intake

B. Acceptable daily intake

C. Acceptable daily interaction

D. Acceptable diet interaction

Ans: B



44. MDI means

A. Mean daily interaction

B. Mean daily intake

C. Mean diet intake

D. Mean diet interaction

Ans: B

45. Components of GMP includes

A. Training staff

B. Quality control of finished product

C. Quality control of raw material

D. All

Ans: D

46. GMP part I includes

A. General requirements

B. Warehousing area

C. Personnel

D. All

Ans: D

47. Quarantine includes

A. Storage of finished good

B. Storage of final products

C. Storage of raw materials

D. Destination of raw material

Ans: A

48. Part II of GMP includes

A. SOP’s

B. Distribution

C. Medical services

D. None

Ans: A

49. There should be…………sq. feet area for quality control selection

A. 160

B. 150

C. 190

D. 200

Ans: B

50. Machinery required for manufacturing of medicines comes under

A. Part-1



B. Part-2

C. Both

D. None

Ans: B

51. Qualitative test for glycosides includes

A. Raymond’s Test

B. Kiddes Reagents Test

C. Tollen’s Test

D. All of above

Ans: D

52. Borntrager’s Test is used for detection of

A. Antrhaquinone glycosides

B. Cardiac glycosides

C. Saponin glycosides

D. Flavone Glycosides

Ans: A

53. Tannins produce deep red color with

A. Potassium ferricyanide + ammonia

B. Ferric chloride + ammonia

C. Potassium ferricyanide + Ferric Chloride

D. Vanillin HCl reagent

Ans: A

54. Karl Fischer method is used for determination of

A. Boiling Point

B. Moisture content

C. Ash Value

D. Optical rotation

Ans: B

55. Biological source of menthol ……………

A. Mentha piperita

B. Mentha Aquatica

C. Mentha spicata

D. All of above

Ans: D

56. Artemisin drug is used against

A. Plasmodium falciparum

B. Plasmodium vivex

C. A & B



D. None

Ans: A

57. Artemisin is isolate from the plant

A. Artemisia annua

B. Artemisia aquatica

C. Artemisia indica

D. All of above

Ans: A

58. Sennosides are

A. Hydroxyantracene glycosides

B. Phenol glycoside

C. Aldehyde glycoside

D. Cyanophoric glycoside

Ans: A

59. Diosgenin can be isolate by

A. Alcoholic Extraction method

B. Acid Hydrolysis Method

C. Fermentation cum acid hydrolysis

D. All of above

Ans: D

60. Rutin is isolated from

A. Ginko biloba

B. Ginko picrata

C. Ginko lanata

D. All of above

Ans: A

61. Atropine is obtained from

A. Atropa belladonna

B. Datura stramonium

C. Hyocyamus niger

D. All of above

Ans: D

62. Vitali-Morin reaction is used for identification of

A. Quinine

B. Atropine

C. Morphine

D. Ephedrine

Ans: B



63. Atropine can be analysed by

A. GC/MC Analysis

B. HPLC Analysis

C. HPTLC Analysis

D. A & B

Ans: D

64. Family of Rauwolfia……

A. Apocyanaceae

B. Papaveraceae

C. Gentaceae

D. Solanaceae

Ans: A

65. Sarpgandha is also known as

A. Indian snakeroot

B. Wintercherry

C. Wild cherry

D. None

Ans: A

66. ……………..is methylxanthin class drug.

A. Caffeine

B. Ephedrine

C. Morphine

D. Quinine

Ans: A

67. Caffeine can identify by

A. Murexide test

B. Vitali Morin test

C. Meconic acid test

D. All of above

Ans: A

68. Caffeine isobtained form

A. Coffea arabica

B. Coffea liberica

C. Thea sinensis

D. All of above

Ans: D

69. Analysis of caffeine can be done by

A. HPLC

B UV/Vis Spectrophotometry



C. FTIR Spectrophotometry

D. All of above

Ans: D

70. Podophyllotoxin is obtained

A. Podophyllum hexandrum

B. Podophyllum emodi

C. Podophyllum pellatum

D. All of above

Ans: D

71. Steptomycin can be identified by

A. Maltol Formation

B. Phenol reagent

C. A & B

D. None

Ans: C

72. DOP full form is

A. Dioctyl -Phthalate

B. Diocto-Phylline

C. Dioctane phthalate

D. None

Ans: A

73. Which natural product is used as Hypnotic Agents?

A. Zizyphus jujuba

B Valeriana officinalis

C. A & B

D. None

Ans: C

74. Tannin produce………………..color with ferric choride

A. Dark Blue color

B. Red color

C. Yellow color

D. Orange color

Ans: A

75. Refractive index value of Castor oil…..

A. 1.475-1.479

B. 1.464-1.468

C. 1.45-1.459

D. 1.51-1.52

Ans: A



76. Melting point of Aloe………0C

A. 168-178 0C

B. 172-176 0C

C. 180-185 0C

D. 179-180 0C

Ans: A

77. Which qualitative test is used for proteins…….?

A. Ninhydrin

B. Biuret

C. Froth Test

D. A & B

Ans: D

78. Which Drug is used as tranquiliser?

A. Hypercium perforatum

B. Humulus luppulus

C. Scutellaria laterifolia

D. All of above

Ans: D

79. Which drug is not used as anticancer agent

A. Paclitaxel

B. Topotecan

C. Aaptamine

D. Amla

Ans: D

80. Which dietary source is used as anticancer agnet?

A. Apricots

B. Tomato

C. Berries

D. All

Ans: D

81. Properties of extraction solvent includes

A. Inert

B. Non toxic

C. Not easily inflammable

D. All

Ans: D

82. Estimation of citral can be done by

A. Gas Liquid Chromatography

B. HPLC



C.HPTLC

D. FTIR

Ans: A

83. Citral can be obtained by

A. Fractional Distillation

B. Maceration

C. Microwave assisted method

D. None

Ans: A

84. Libermann-Buchard test is used for identification of

A. Diosgenin

B. Quinine

C. Mophine

D. Artemisin

Ans: A

85. Morphine analysis can be done by

A. GC-MS

B. HPLC

C. Ion exchange chromatography

D. All

Ans: D

86. When Morphine sprinkled on nitric acid gives

A. Orange red color

B. Greenish Blue color

C. Dark Violet color

D. Deep red color

Ans: A

87. Bryostatin is used as

A. Antidiabetic agent

B. Anticancer agent

C. Tranquiliser

D. Hepatoprotective agent

Ans: B

88. Andrographis paniculata is used as

A. Hepatoprotective agent

B. Antiasthmatic agent

C. Immunomodulator

D. A & C

Ans: D



89. Which categories of drug are used as Anti-asthmatic agent?

A. Bronchodilator

B. Anti-inflammatory agent

C. A & B

D. None

Ans: C

90. Phyllanthus niruri is used as

A. Lythotryptic agent

B. Hypolipidemic agent

C. Immunomodulator agent

D. All

Ans: A

91. Identification of penicillin can be done by

A. HPLC

B. HPTLC

C. TLC

D. GC

Ans: C

92. Physical evaluation for standardization of herb includes

A. Moisture content

B. Extractive value

C. Ash Value

D. All

Ans: D

93. Biologicall evaluation for standardization of herb includes

A. Microbial contamination

B. Mycotoxin

C. Toxicological studies

D. A & C

Ans: D

94. Garcinia standardized plant extract is prepared by

A. Maceration

B. Percolation

C. Soxhlet apparatus

D. All

Ans: A

95. Which fruit is also known as Malabar tamarind

A. Amla



B. Winter cherry

C. Garcinia

D. Garlic

Ans: C

96. Turmeric is obtained from

A. Curcuma longa

B. Curcuma amada

C. Curcuma aromatica

D. All

Ans: D

97. Turmeric Plant extract is prepared by

A. Maceration

B. Percolation

C. Soxhlet apparatus

D. All

Ans: C

98. Ashawgandha is used in treatment of

A. Tuberculosis

B. Insomnia

C. Leukoderma

D. All

Ans: D

99. Ashawgandha plant extract is prepared by

A. Maceration

B. Percolation

C. Ultrasound assisted method

D. Digestion

Ans: C

100. What is QMS

A. Quality Management System

B. Quality Management Standard

C. Quantity margin system

D. None

Ans: A

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SEMESTER VIII PHARMACOGNOSY-VI (2280005) Multiple Choice