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Section 5-2Section 5-2“Mitosis“Mitosis””
Write everything that isWrite everything that is BLACKBLACK
5.2 Mitosis and Cytokinesis
KEY CONCEPT KEY CONCEPT Cells divide during mitosis and Cells divide during mitosis and cytokinesis.cytokinesis.
5.2 Mitosis and Cytokinesis
DNA doublehelix
DNA andhistones
Chromatin SupercoiledDNA
•When the cell grows large enough it needs to When the cell grows large enough it needs to dividedivide
•Cell Division is called Cell Division is called MitosisMitosis
•First the DNA must coil up to make First the DNA must coil up to make ChromosomesChromosomes
5.2 Mitosis and Cytokinesis
DNA strands in the nucleus are called DNA strands in the nucleus are called chromatinchromatin
• One half of a duplicated One half of a duplicated chromosome is a chromosome is a chromatidchromatid
• Sister chromatids are Sister chromatids are held together at the held together at the centromerecentromere
• Telomeres protect DNA Telomeres protect DNA and do not include and do not include genesgenes Condensed, duplicated Condensed, duplicated
chromosomechromosome
chromatidchromatid
telomeretelomere
centromerecentromere
telomere
5.2 Mitosis and Cytokinesis
Parent cell
centriolescentrioles
spindle fibersspindle fibers
centrosomecentrosome
nucleus withnucleus withDNADNA
• Interphase Interphase prepares the cell to prepares the cell to dividedivide
• During During interphase, the interphase, the DNA is DNA is duplicatedduplicated
Mitosis produces 2 genetically Mitosis produces 2 genetically identicalidentical daughter cells daughter cells
5.2 Mitosis and Cytokinesis
• Mitosis divides the cell’s nucleus in 4 phasesMitosis divides the cell’s nucleus in 4 phases
ProphaseProphase: chromosomes : chromosomes condense and spindle fibers condense and spindle fibers formform
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5.2 Mitosis and Cytokinesis
MetaphaseMetaphase: chromosomes : chromosomes line up in the line up in the middlemiddle of the of the cellcell
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5.2 Mitosis and Cytokinesis
AnaphaseAnaphase: sister chromatids : sister chromatids separate to opposite sides of separate to opposite sides of the cellthe cell
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5.2 Mitosis and Cytokinesis
TelophaseTelophase: the new nuclei form : the new nuclei form and chromosomes begin to and chromosomes begin to uncoiluncoil
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5.2 Mitosis and Cytokinesis
• CytokinesisCytokinesis (division of the cytoplams) (division of the cytoplams) differs in animal and plant cellsdiffers in animal and plant cells
–CytokinesisCytokinesis splits the 2 new splits the 2 new cells…cells…
– In animal cells, In animal cells, the membrane the membrane pinches closedpinches closed
– In plant cells, a In plant cells, a cell platecell plate forms forms