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School District of Springfield Township Springfield Township High School Course Overview Course Name: Biology (Academic) Grade Level: 10 Course Description Biology (Academic) is a laboratory oriented course that studies the nature of life, ecology, cells, genetics and evolution. Emphasis is on the functions at the molecular level. Unit Titles Unit 1: The Science of Biology Unit 2: The Chemistry of Life Unit 3: Ecology Unit 4: Populations Unit 5: Humans in the Biosphere Unit 6: Cell Structure and Function Unit 7: Photosynthesis and Cellular Respiration Unit 8: DNA and Protein Synthesis Unit 9: Cell Division Unit 10: Genetics Unit 11: Evolution Essential Questions 1. How does a scientific theory develop? 2. How do we know if something is alive? 3. How is life a product of the organization and interaction of matter? 4. How do organisms interact with and depend on each other in an ecosystem? 5. How are organisms impacted by the nonliving components of an ecosystem? 6. What factors affect population size? 7. How does the greenhouse effect maintain the biosphere’s temperature range? 8. Why is biodiversity important? 9. How is structure related to function at the various levels of cellular organization? 10. How do organisms maintain a biological balance between their internal and external environments? 11. How do organisms obtain and use energy to carry out their life processes? 12. How do organisms use DNA and RNA to make proteins? 13. What factors affect gene expression? 14. How do biotechnologies impact the fields of medicine, forensics, and agriculture?

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School District of Springfield Township

Springfield Township High School Course Overview

Course Name: Biology (Academic) Grade Level: 10

Course Description Biology (Academic) is a laboratory oriented course that studies the nature of life,

ecology, cells, genetics and evolution. Emphasis is on the functions at the molecular

level.

Unit Titles Unit 1: The Science of Biology

Unit 2: The Chemistry of Life

Unit 3: Ecology

Unit 4: Populations

Unit 5: Humans in the Biosphere

Unit 6: Cell Structure and Function

Unit 7: Photosynthesis and Cellular Respiration

Unit 8: DNA and Protein Synthesis

Unit 9: Cell Division

Unit 10: Genetics

Unit 11: Evolution

Essential Questions

1. How does a scientific theory develop?

2. How do we know if something is alive?

3. How is life a product of the organization and interaction of matter?

4. How do organisms interact with and depend on each other in an ecosystem?

5. How are organisms impacted by the nonliving components of an ecosystem?

6. What factors affect population size?

7. How does the greenhouse effect maintain the biosphere’s temperature range?

8. Why is biodiversity important?

9. How is structure related to function at the various levels of cellular organization?

10. How do organisms maintain a biological balance between their internal and

external environments?

11. How do organisms obtain and use energy to carry out their life processes?

12. How do organisms use DNA and RNA to make proteins?

13. What factors affect gene expression?

14. How do biotechnologies impact the fields of medicine, forensics, and agriculture?

15. How do new cells arise from pre-existing cells?

16. How does biological inheritance affect the genotypes and phenotypes of

offspring?

17. How do natural processes as described by the theory of evolution effect change in

a population over time?

Enduring Understandings

Unit 1: The Science of Biology

Scientific terms

o Hypothesis and prediction

o Inference and observation

o Principle

o Theory

o Law

o Fact and opinion

Common Characteristics of Life

o Composed of one or more units called cells

o Obtain and use matter and energy to carry out life processes

o Reproduce and pass their genetic material on to the next generation

o Maintain homeostasis

o Grow, develop and eventually die

o Detect and respond to stimuli

o Adapt and evolve at the population level

Unit 2: The Chemistry of Life

Chemical structure of water

Polarity of water/hydrogen bonding and related properties

Examples of how the properties of water make life on earth possible

Levels of biochemical organization

Chemical properties of carbon

Structural shapes of carbon molecules

Monomers vs. polymers

Monomer that forms carbohydrates, proteins and nucleic acids

Dehydration synthesis (condensation) and hydrolysis reactions

Basic structure of the four major classes of biological macromolecules

Importance and use of each macromolecule for biological functions

Enzymes as proteins

Enzyme and substrate specificity/interactions

Effect of enzymes on activation energy and reaction rates

Reusable nature of enzymes

Examples of enzyme controlled reactions in living things

Enzyme activity as a function of specific conditions

Effects of environmental factors (pH, temperature, concentration) on enzyme

function

Unit 3: Ecology

The levels of ecological organization

o Organism

o Population

o Community

o Ecosystem

o Biome

o Biosphere

Abiotic components of an ecosystem

Biotic components of an ecosystem

Characteristics of abiotic and biotic components of earth’s aquatic and terrestrial

ecosystems

The ultimate energy source is the sun.

o Other initial sources of energy (Chemical and heat)

Photosynthesis and cellular respiration

Structure and components of a food chain or food web

Implications of the 10% rule/law (energy pyramids)

Habitat and niche (fundamental and realized)

Symbiotic interactions within an ecosystem

Biogeochemical cycles

o Water, carbon, oxygen, nitrogen

Examples of natural disturbances affecting ecosystems

o Ecological succession

o Natural disasters

Unit 4: Population

Carrying capacity

Limiting factors

o Density dependent

o Density independent

Effects of limiting factors on population dynamics

o Biotic potential

o Environmental resistance

o Increase/decreased/stabilized population growth

o Extinction

o Increased/decreased/stabilized biodiversity

Unit 5: Humans in the Biosphere

Examples of human disturbances affecting ecosystems

o Human overpopulation

o Climate changes

o Introduction of non-native species

o Pollution

o Fires

Effects of human and natural disturbance on ecosystems

o Loss of biodiversity

o Loss of habitat

o Increased rate of extinction

o Disruption of natural biological cycles

Unit 6: Cell Structure and Function

Similarities and differences in structure between prokaryotic and eukaryotic cells

Common features/functions of cells structures in both prokaryotic and eukaryotic

cells

Levels of biological organization from organelle to multicellular organism

o Organelle

o Cell

o Tissue

o Organ

o Organ system

Chemical structure of the plasma membrane (phospholipid bilayer)

Fluid mosaic model

Functions of the plasma membrane

Passive transport mechanisms (diffusion, osmosis, facilitated diffusion)

Active transport mechanisms (pumps, endocytosis, exocytosis)

Examples of Mechanisms

o Thermoregulation

o Water regulation

o Oxygen regulation

o Chemical regulations

pH/Buffer, Hormone, Electrolyte

Unit 7: Photosynthesis and Cellular Respiration

Double membrane structure of mitochondria and chloroplasts

Roles of mitochondria and chloroplasts in energy transformations

Catabolic vs. anabolic chemical reactions as related to metabolism

Overall (summary) chemical equations for photosynthesis and cellular respiration

Basic energy transformations during photosynthesis and cellular respiration

Relationship between photosynthesis and cellular respiration

Molecular structure of ATP

ATP-ADP cycle

Importance of ATP as the energy currency (fuel) for cell transport

Unit 8: DNA & Protein Synthesis

Structure of DNA

o Components of a nucleotide

o Base-pair rule (Chargaff’s Rule)

Semi-conservative/DNA replication process

Structure of eukaryotic chromosomes

Similarities and differences between DNA and RNA

Types of RNA

Transcription uses DNA to make RNA

Translation uses RNA to make a protein

Role of ribosomes, endoplasmic reticulum and Golgi apparatus in assembling,

transporting, packaging, and modifying different proteins

Different types of gene mutations

Possible effect of mutation (change in the DNA sequence) on gene expression

Environmental influences on gene expression

Tools of genetic engineering (gel electrophoresis, PCR, restriction enzymes,

Bacterial and viral plasmids, recombinant DNA, gene splicing, selective breeding,

cloning, DNA sequencing)

Applications of genetic engineering

DNA fingerprinting

Genetically modified organisms in medicine and agriculture

Gene therapy

Stem cell therapy

Human Genome Project

Unit 9: Cell Division

Cell cycle in a non-reproductive, eukaryotic cell

o Interphase (G1, S, G2)

o Nuclear division (mitosis)

o Cytokinesis (plant vs. animal cells)

Phases of mitosis; prophase, metaphase, anaphase, telophase

Phases of meiosis in diploid, gern-line stem cells

Importance of mitosis and meiosis

Outcomes of mitosis and meiosis

Importance of chromosome composition and number in controlling gene

expression

Unit 10: Genetics

Common patterns of inheritance

Tools for predicting patterns of inheritance

o Punnett square

o Pedigree

o Mathematics of probability

Relationship between genotype and phenotype

Unit 11: Evolution

Principles of inheritance as they relate to evolution

Fundamental principles of natural selection

Factors that contribute to speciation

o Isolating mechanisms

o Genetic drift

o Founder effect

o Migration

Examples of variation in populations

Evidence of Evolution

o Fossil

o Anatomical

o Physiological

o Embryological

o Biochemical

o Universal genetic code

Key Skills/Processes

Unit 1: The Science of Biology

Explain the goal of science

o Form a hypothesis

o Describe how scientists test hypothesis

o Explain how a scientific theory develops

o Describe characteristics of living things

o How can life be studied at different levels?

o What measurement systems do most scientists use?

o How are light microscopes and electron microscopes similar? How are

they different?

o Describe two common laboratory techniques

o Explain why it is important to work safely in biology

Explain homeostasis

Unit 2: The Chemistry of Life

Describe the unique properties of water

Explain how the unique properties of water make life on earth possible

Describe the structure of a carbon atom

Explain how carbon atoms bond to form biological macromolecules

Describe how biological macromolecules form from monomers

Compare the structure and function of carbohydrates, lipids, proteins, and

nucleic acid in organisms

Explain how enzymes act as catalysts to regulate biochemical reactions

Explain how environmental factors affect the function and reaction rate of

enzymes

Interpret graphs to analyze enzyme catalyzed reactions

Unit 3: Ecology

Describe and differentiate between the levels of ecological organization

Describe characteristic biotic and abiotic components of terrestrial and

aquatic ecosystems

Describe how energy flows through an ecosystem

Describe biotic interactions within an ecosystem

Describe the niche of an organism

Describe how matter recycles in an ecosystem

Describe how ecosystems change in response to natural and human

disturbances

Unit 4: Populations

Describe the effects of limiting factors on population dynamics and

potential species extinction

Unit 5: Humans in the Biosphere

Identify the characteristics of sustainable development

Describe how human activities affect land, air and water resources

Define biodiversity and explain its value

Identify current threats to biodiversity

Describe the goal of conservation biology

Describe two types of global change of concern to biologists

Unit 6: Cell Structure and Function

Describe the common characteristics exhibited by all living things-both

prokaryotic and eukaryotic

Compare cellular structures and their functions in prokaryotic and

eukaryotic cells

Describe and interpret relationships between structure and function at the

organelle, cell, tissue, organ, organ system, and multicellular organism

level of organization

Describe how the structure of the plasma membrane allows it to function

as a regulatory structure and/or protective barrier for a cell

Compare and contrast active vs. passive transport mechanisms

Describe how membrane-bound cellular organelles facilitate intracellular

transport of materials

Explain mechanisms organism use to maintain homeostasis

Unit 7: Photosynthesis and Cellular Respiration

Describe the structure of mitochondria and chloroplasts in eukaryotic cells

Describe the fundamental roles of plastids (e.g., chloroplasts) and

mitochondria in energy transformations

Compare the basic transformations of energy during photosynthesis and

cellular respiration

Describe the structure of ATP

Describe the role of ATP in biochemical reactions

Unit 8: DNA and Protein Synthesis

Describe how DNA replication results in the transmission and/or

conservation of the genetic information

Explain the structural relationships between DNA, genes and

chromosomes

Explain the unified process of protein synthesis

Describe the role of the nucleus, ribosomes, ER, and Golgi apparatus in

the production and processing of proteins

Describe how genetic mutations alter DNA sequence and may or may not

affect the expression of a gene

Describe tools used in genetic engineering

Describe applications of genetic engineering

Explain how genetic engineering has impacted the fields of medicine,

forensics, and agriculture

Unit 9: Cell Division

Describe the events that occur during the cell cycle

Compare and contrast the processes and outcomes of mitotic and meiotic

nuclear divisions

Describe processes that can alter composition or number of chromosomes

(chromosomal mutations)

Unit 10 - Genetics

Explain the functional relationships between DNA, genes, alleles, and

chromosomes and their role in inheritance

Describe and/or predict observed patterns of inheritance

Unit 11 - Evolution

Explain how natural selection can impact allele frequencies of a

population

Describe the factors that can contribute to the development of a new

species

Explain now genetic mutations may result in genotypic and phenotypic

variations within a population

Interpret evidence supporting the theory of evolution

Use scientific terms properly in written and oral form

Key Vocabulary

Unit 1 – The Science of Biology science, observation, data, inference, hypothesis, spontaneous generation, controlled

experiment, manipulated (independent) variable, responding (dependent) variable,

theory, biology, catabolism, anabolism, metabolism, homeostasis, metric system,

compound light microscope, electron microscope, cell culture, cell fractionation,

inference, thermoregulation, stimuli

Unit 2 – The Chemistry of Life

matter, Atom, nucleus, electron, neutron, proton, element, isotope, ion, compound, ionic

bond, covalent bond, molecule, vander Waals forces, cohesion, surface tensions

transpiration, solution, solute, solvent, suspensions, pH scale, acid, base, buffer,

monomer, polymer, polymerization, carbohydrates, monosaccharides, polysaccharides,

dehydration synthesis, hydrolysis, lipids, nucleic acids, nucleotides, ribonucleic acid,

deoxyribonucleic acid, protein, amino acids, chemical reaction, reactants, products,

activation energy, catalyst, enzymes, substrates, active site, digestion, amylase,

peristalsis, villi

Unit 3 – Ecology ecology, biosphere, species populations, communities, ecosystem, biome, autotrophs,

producers, photosynthesis, chemosynthesis, herbivores, carnivores, omnivores,

detrivore, decomposers, food chain, food web, trophic level, ecological pyramid,

biomass, biogeochemical cycles, water cycle, nitrogen cycle, phosphorous cycle, carbon

cycle, evaporation, transpiration, nutrients, nitrogen fixation, denitrification, primary

productivity, limiting nutrient, algal bloom, weather, climate, greenhouse effect, polar

zones, temperate zones, tropical zone, biotic factors, abiotic factors, niche, resource,

competitive exclusion principle, predation, symbiosis, mutualism, commensalism,

parasitism, ecological succession, primary succession, pioneer species, secondary

succession, biome, tolerance, taiga, permafrost, plankton, phytoplankton, zooplankton,

wetland, estuaries, detritus, salt marshes, mangrove swamps, photic zone, aphotic zone,

zonation, coastal ocean, kelp forests, coral reefs, benthos

Unit 4 – Populations

population density, immigration, emigration, exponential growth, logistic growth,

carrying capacity, limiting factor, density-dependent limiting factor, predator-prey

relationship, density-independent limiting factors, demography, demographic transition,

age-structure diagram

Unit 5 – Humans in the Biosphere

agriculture, monoculture, green revolution, renewable resources, nonrenewable

resource, sustainable development, soil erosion, desertification, deforestation,

aquaculture, smog, pollutant, acid rain, biodiversity, genetic diversity, extinction,

endangered species, habitat fragmentation, biological magnification, nonnative species,

conservation, ozone layer, global warming, extinction

Unit 6 – Cell Structure and Function

cell theory, nucleus, eukaryotes, prokaryotes, organelles, cytoplasm, nuclear envelope,

chromatin, chromosomes, nucleolus, ribosomes, endoplasmic reticulum, golgi

apparatus, lysosomes, vacuoles, mitochondria, chloroplasts, cytoskeleton, centrioles,

cell membrane, cell wall, lipid bilayer, plasma membrane, selectively permeable,

vesicles, concentration gradient, diffusion, equilibrium, osmosis, isotonic, hypertonic,

hypotonic, facilitated diffusion, active transport, endocytosis, phagocytosis, pinocytosis,

exocytosis, pumps, cell specialization, tissue, organ, organ system, nephron, alveoli,

neuron, action potential, synapse, neurotransmitter

Unit 7 – Photosynthesis and Cellular Respiration

autotroph, heterotroph, adenosine triphosphate, ATP, photosynthesis, pigments,

chlorophyll, thylakoids, photosystems, stroma, NADP+, light-dependent reactions,

ATP synthase, Calvin Cycle, calorie, glycolysis, cellular respiration, NAD+,

fermentation, anaerobic, aerobic, Krebs, cycle, electron transport chain

Unit 8 – DNA and Protein Synthesis

adenine, amino acids, anticodon, Chargaff’s Rule, chromosomes, codon, complimentary

strand, cytosine, deletion, deoxyribonucleic acid (DNA), deoxyribose, DNA replication,

double helix, endoplasmic reticulum, enzymes, frameshift mutation, gene mutation

genes, guanine, hydrogen bond, insertion, missense, nonsense, nucleotide, nucleus,

parent strand, phenotype, phosphate group, point mutation, polypeptides, proteins,

ribonucleic acid (RNA) ribosomes, semi-conservative model, thymine, transcription,

translation, triplet, uracil, biotechnology, cloning, DNA fingerprinting, DNA

sequencing, electrophoresis, gene splicing, gene therapy, genetic engineering,

genetically modified organisms, plasmids, polymerase chain reaction (PCR),

recombinant DNA, restriction enzymes, selective breeding, stem cell, transgenic

organism

Unit 9 – Cell Division

cell division, mitosis, cytokinesis, chromatids, centromeres, interphase, cell cycle,

prophase, centrioles, spindle, metaphase, anaphase, telophase, cleavage furrow, cyclin,

cancer, homologous, diploid, haploid, meiosis, somatic cells, germ-line cells, zygote,

daughter cells, chromatin, chromatid, histone, centromere, spindle (fiber)

Unit 10 – Genetics

genetics, fertilization, true-breeding, trait, hybrid, gene allele, segregation, gamete,

probability punett square, homozygous, heterozygous, phenotype, genotype, gene map,

independent assortment, incomplete dominance, codominance, multiple alleles,

polygenic traits, karyotype, sex chromosomes, autosomes, pedigree, sex-linked,

nondisjunction, test cross

Unit 11 - Evolution

evolution, fossil, natural selection, artificial selection, struggle for existence, fitness,

adaptation, survival of the fittest, homologous structures, vestigial organs, convergent

evolution, allele frequency, speciation, geographic isolation, speciation, genetic drift,

founder effect, migration

Core Resources:

Miller/Levine – Prentice Hall Biology text book, 2008, Pearson Education, Inc.

Miller/Levine – Prentice Hall Biology Reading and Study Workbook, 2008

Miller/Levine – Prentice Hall Biology Laboratory Manual, 2008

Pennsylvania Keystone Standards Guiding Course

Unit 1 – The Science of Biology

3.1.1.10.A1. Explain the characteristics of life common to all organisms

3.1.B.A9. Distinguish between the scientific terms: hypothesis, inference, law, theory,

principle, fact and observation

Unit 2 – The Chemistry of Life

3.1.B.A8, 3.1.B.A5, 4.2.5.C. Describe the unique properties of water and how these

properties support life on Earth (e.g., freezing point, high specific heat, cohesion)

3.1.B.A7, 3.2.C.A2. Explain how carbon is uniquely suited to form biological

macromolecules

3.1.B.A7, 3.1.B.A8, 3.1.B.A2, 3.1.C.A2, 3.1.C.A7. Describe how biological

macromolecules form from monomers

3.1.B.A7, 3.1.B.A2, 3.1.C.A2, 3.1.C.A7. Compare the structure and function of

carbohydrates, lipids, proteins, and nucleic acids in organisms

3.1.B.A2, 3.1.B.A7. Describe the role of an enzyme as a catalyst in regulating a specific

biochemical reaction

3.1.B.A2, 3.1.B.A7. Explain how factors such as pH, temperature, and concentration

levels can affect enzyme function

Unit 3 – Ecology

4.1.4.A, 4.1.10.A, 4.4.6.A, 4.5.3.D, 4.1.7.A, 4.1.7.C. Describe the levels of ecological

organization (i.e., organism, population, community, ecosystem, biome and biosphere)

4.1.7.A, 4.1.4.B, 4.1.4.C, 4.4.3.C, 4.1.3.A, 4.2.10.A, 4.4.5.C. Describe characteristic

biotic and abiotic components of aquatic and terrestrial ecosystems

4.1.4.C, 4.1.10.C, 4.1.3,C, 4.1.5.A, 4.1.7.C, 4.1.12.C, 4.1.5.C. Describe how energy

flows through an ecosystem (e.g., food, chains, food webs, energy pyramids)

4.1.7.A, 4.1.10.A, 4.5.3.D, 4.5.6.D Describe biotic interactions in an ecosystem (e.g.,

competition, predation, symbiosis)

4.1.4B, 4.2.7.A, 4.5.4.C, 4.3.4.D, 4.1.7.B, 4.3.12.A, 4.5.8.C, 3.1.B.A2, 4.2.5.A, 4.4.3.C.

Describe how matter recycles through an ecosystem(i.e., water cycle, carbon cycle,

oxygen cycle, and nitrogen cycle

Unit 4 – Populations

4.1.4.A, 4.2.10.C, 4.2.10.A, 4.4.6.B, 4.1.10.A, 4.5.3.D, 4.2.7.A, 4.4.3.C, 4.1.12.A,

4.5.5.D, 4.2.8.A, 4.4.5.C, 4.1.7.E, 4.5.6.D, 4.2.10.B, 4.5.7.B, 4.1.10.E, 4.5.10.D, 4.4.6.A,

4.5.7.C, 4.1.4.E. Describe the effects of limiting factors on population dynamics and

potential species extinction

Unit 5 – Humans in the Biosphere

4.4.10A, 4.1.7.E, 4.2.10.B, 4.3.10.B, 4.1.10.B, 4.1.10.E, 4.2.12.B, 4.5.10.B, 4.1.12.A,

4.5.10.D, 4.2.10.C, 4.5.12.B, 4.1.4.A, 4.2.8.A, 4.2.12.C, 4.5.4.C, 4.1.as.C, 4.2.10.A,

4.3.12.A, 4.5.7.C, 4.1.4.E, 4.2.12.A. Describe how ecosystems change in response to

natural and human disturbances (e.g., climate changes, introduction of nonnative species,

pollution, fires)

Unit 6 – Cell Structure and Function

3.1.B.A1, 3.1.B.C2, 4.1.3.A, 4.1.4.A. Describe the characteristics of life shared by all

prokaryotic and eukaryotic organisms

3.1.B.A5, 3.1.B.C2. Compare cellular structures and their functions in prokaryotic and

eukaryotic cells

3.1.B.A5, 3.1.B.A6, 3.1.B.A1. Describe and interpret relationships between structure and

function of various levels of biological organization (i.e., organelles, cells, tissues,

organs, organ systems, and multicellular organisms)

3.1.B.A5, 3.1.B.A2, 3.1.B.A4, 3.1.B.A7, 3.2.C.A1, 3.2.P.B6. Describe how the structure

of the plasma membrane allows it to function as a regulatory structure and/or protective

barrier for a cell

3.1.B.A5, 3.1.B.A2, 3.1.B.A7, 3.2.C.A1, 3.2.P.B6. Compare the mechanisms that

transport materials across the plasma membrane (i.e., passive transport-diffusion,

osmosis, facilitated diffusion; and active transport-pumps, endocytosis, exocytosis)

3.1.B.A5, 3.1.B.A2. Describe how membrane0bound cellular organelles (e.g.,

endoplasmic reticulum, Golgi apparatus) facilitate the transport of materials within a cell

3.1.B.A8, 3.1.B.A5, 4.5.4.D, 4.2.4.C. Explain how organisms maintain homeostasis

(e.g., thermoregulation, water regulation, oxygen regulation)

3.1.12.A1. Relate changes in the environment to various organisms’ ability to

compensate using homeostatic mechanisms

3.1.B.A5, 3.1.B.B3, 3.1.B.B5, 3.1.C.B3. Describe the role of ribosomes, endoplasmic

reticulum, Golgi apparatus and the nucleus in the production of specific types of proteins

Unit 7 – Photosynthesis and Cellular Respiration

3.1.B.A2, 3.1.B.A5, 3.1.C.A1. Describe the fundamental roles of plastids (e.g.,

chloroplasts) and mitochondria in energy transformations

3.1.B.A2, 3.1.B.A5, 3.1.C.A1, 4.1.10.C. Compare the basic transformation of energy

during photosynthesis and cellular respiration

3.1.B.A2, 3.1.C.A1, 3.1.C.A2. Describe the role of ATP in biochemical reactions

Unit 8 – DNA and Protein Synthesis

3.1.B.B1, 3.1.B.B3, 3.1.B.B5, 3.1.B.C2, 3.1.C.C2. Describe how the process of DNA

replication results in the transmission and/or conservation of genetic information

3.1.B.B1, 3.1.B.B3, 3.1.B.B5, 3.1.C.B3, 3.1.C.C2. Describe how the processes of

transcription and translation are similar in all organisms

3.1.B.B1, 3.1.B.B3, 3.1.B.C2, 3.1.C.B3, 3.1.C.C2. Describe how genetic mutations alter

the DNA sequence and may or may not affect phenotype (e.g., silent, nonsense, frame-

shift)

3.1.B.B4, 4.4.7.A, 4.4.10.A, 4.4.12.A, 4.4.7.B, 4.4.10.B, 4.4.12.B. Explain how genetic

engineering has impacted the fields of medicine, forensics, and agriculture (e.g., selective

breeding, gene splicing, cloning, genetically modified organisms, gene therapy)

Unit 9 – Cell Division

3.1.B.A4, 3.1.B.A5, 3.1.B.B2, 3.1.B.B3, 3.1.B.B5, 3.1.B.C2, 3.1.C.C2. Describe the

events that occur during the cell cycle; interphase, nuclear division (i.e., mitosis, or

meiosis), cytokinesis

3.1.B.A4, 3.1.B.A5, 3.1.B.B2, 3.1.B.B3, 3.1.B.B5, 3.1.B.C2, 3.1.C.C2. Compare the

processes and outcomes of mitotic and meiotic nuclear divisions

Unit 10 – Genetics

3.1.B.V1, 3.1.B.B5, 3.1.B.B2, 3.1.B.B3, 3.1.C.C2. Explain the functional relationships

between DNA, genes, alleles and chromosomes and their roles in inheritance.

3.1.BB5. Describe and/or predict observed patterns of inheritance (i.e., dominant,

recessive, co-dominance, incomplete dominance, sex-linked, polygenic, and multiple

alleles)

3.1.B.B1, 3.1.B.B2, 3.1.B.B3, 3.1.C.C2. Describe processes that can alter composition or

number of chromosomes (i.e., crossing-over, non-disjunction, duplication, translocation,

deletion, insertion and inversion)

Unit 11 – Evolution

3.1.B.C1. Explain how natural selection can impact allele frequencies of a population

3.1.B.C1, 3.1.B.C2. Describe the factors that can contribute to the development of a new

species (e.g., isolating mechanisms, genetic drift, founder effect, migration)

3.1.B.C2, 3.1.B.B1. Explain how genetic mutations may result in genotypic and

phenotypic variations within a population

3.1.B.C3, 3.1.B.C1, 3.1.B.B3. Interpret evidence supporting the theory of evolution (i.e.,

fossil, anatomical, physiological, embryological, biochemical and universal genetic code)

Prepared June 2011-NS

Approved-chr