SCHEDULE-AT-A-GLANCE2018 PNS ANNUAL MEETING

1600- 1630 Coff ee Break The Atrium

1630- 1800 Abstract Presentati ons

1800- 2100 Welcome Reception Maryland Science Center Inner Harbor

SUNDAY, 22 JULY0730- 0830 Poster viewing +breakfast/coff ee

Balti more Ballroom A&B

0730- 0830 Clinical TrialsMaryland ABCD

0830- 0900 Richard Bunge: Biology of NerveErika Holzbauer Maryland ABCD

0900- 1030 6 Oral Abstracts (15 min each)Maryland ABCD

1030- 1100 Coff ee BreakThe Atrium

1100- 1130 Jack Griffin: Regeneration David Parkinson Maryland ABCD

1130- 1230 10 Oral Posters (5 min each)Maryland ABCD

1230- 1300 Lunch and Poster ViewingBalti more A&B

1300- 1400 Poster Session – Stand-by TimesBalti more Ballroom A&B

1400- 1800 INFLAMMATORY NEUROPATHY CONSORTIUM (INC) Maryland Ballroom ABCD

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES (CMTR) Maryland Ballroom EF

DIABETES/ PAIN Watertable Ballroom

1600-1630 Coffee Break The Atrium

1800-1900 Ionis Pharmaceuticals Maryland EF

Maryland Foyer

FRIDAY, 20 JULYTBA Registrati on

Main Lobby

SATURDAY, 21 JULYALL- DAY SATURDAY EDUCATION COURSE

0730-1800 Registrati on Atrium

0900-0945 An Overview of Peripheral Nerve Anatomy and PathologySteve Scherer & PNS Educati on Committ eeMaryland Ballroom CDF

0945-1030 Disease mechanisms in the inherited neuropathies Vincent TimmermanMaryland Ballroom CDF

1030-1100 Coffee Break The Atrium

1100-1200 New anti bodies and mechanisms in immune mediated neuropathy Claudia SommerMaryland Ballroom CDF

1200-1230 How I treat paraproteinaemic neuropathiesMichelle MauermannMaryland Ballroom CDF

1230-1400 Lunch The Atrium

1400-1445 Geneti c therapies in CMT and related disorders, how they work and clinical applicati ons John SvarenMaryland Ballroom CDF

1445-1515 The journey from preclinical to clinical trial -Lessons learnt Davide PareysonMaryland Ballroom CDF

1515-1600 What makes a good outcome measure and how to design one Josh Burns Maryland Ballroom CDF

1800-1900 Sponsor Symposia Maryland ABCD

1900-2000 Junior Reception

MONDAY, 23 JULY0700- 0830 Poster viewing +breakfast/coff ee

Balti more Ballroom A&B

0730- 0830 CSL BehringMaryland Ballroom ABCD

0730- 0830 Sponsor SymposiaMaryland Ballroom EF

0830- 0900 Arthur K Asbury: GBS/CIDP/InflammatoryKevin O’Connor Maryland Ballroom ABCD

0900-1030 6 Oral Abstracts (15 min each)

1030-1100 Coffee BreakThe Atrium

1100-1130 PK Thomas: Inherited NeuropathiesAlessandra Bolino Maryland ABCD

1130-1230 10 Oral Posters (5 min each) Maryland Ballroom ABCD

1230-1300 PNS Annual General Meeting (all welcome)Maryland Ballroom ABCD

1300- 1400 Lunch/Poster Session Baltimore Ballroom A&B

1400- 1800 INFLAMMATORY NEUROPATHY CONSORTIUM (INC) Maryland Ballroom ABCD

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES (CMTR) Maryland Ballroom EF

DIABETES/ PAIN Watertable Ballroom

1600-1630 Coffee BreakThe Atrium

1800- 1900 Alnylam Maryland EF

1800-1900 GrifolsMaryland ABCD

1900-2000 All Member Reception The Atrium

TUESDAY, 24 JULY0730-0830 Poster viewing +breakfast/ coffee

Balti more Ballroom A&B

0730-0830 Clinical TrialsMaryland Ballroom ABCD

0830-0900 Peter J Dyck LecturePeter McNaughtonMaryland ABCD

0900-1030 6 Oral Abstracts (15 min each)

1030-1100 Coffee BreakThe Atrium

Pembroke Lecture: Cell BiologyCraig BlackstoneMaryland ABCD

1130- 1230 10 Oral Posters (5 min each)Maryland ABCD

1230- 1330 Lunch and Poster ViewingBalti more Ballroom A&B

1300- 1400 Poster Session – Stand-by Times

1400- 1600 Late Breaking AbstractsMaryland ABCD

1600- 1630 Coff ee BreakThe Atrium

1630- 1730 Hot Topics/What’s NewMaryland ABCD

1730- 1830 Keynote Speaker + Prizes: Spinal muscular Atrophy from gene to treatment Arthur Burghes Maryland ABCD

1900 PNS Closing Recepti on Camden Yards: Orioles vs. Red Sox Baseball Game

WEDNESDAY, 25 JULYIndividual Meetings

1100-1130

SUNDAY, 22 JULY INFLAMMATORY NEUROPATHY CONSORTIUM (INC)

1400-1430

1430-1500

1500-1600

1600-1630

1630-1700

1700-1730

1730-1800

INC Business Maryland ABCD

POEMS Satoshi Kuwabara Maryland ABCD

Oral Abstracts Maryland ABCD

Coffee Break Maryland Foyer

Debates: The next best clinical trial in CIDP: B-cell or T-cell immunomodulating therapy?Bernd Kieseier and Mazen DimachkieMaryland ABCD

Mechanisms of Ig Mel Berger Maryland ABCD

Oral Abstracts Maryland ABCD

MONDAY, 23 JULY INFLAMMATORY NEUROPATHY CONSORTIUM (INC)

1400-1430

1430-1500

1500-1600

1600-1630

1630-1700

1700-1730

1730-1800

INC Business Maryland ABCD

Paraneoplastic or Sensory Neuropathies JC Antoine Maryland ABCD

Oral Abstracts Maryland ABCD

Coffee Break Maryland Foyer

Debates: Electrodiagnosis of Gullain-Barreˊ syndrome: new insights from analysis of re-vised diagnostic criteria and IGOS Nortina Shahrizalia and Yusuf Rajabally Maryland ABCD

MMN Leonard Van Den Berg Maryland ABCD

Oral Abstracts Maryland ABCD

SUNDAY, 22 JULY MONDAY, 23 JULY

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES

CONSORTIUM (CMTR)

CHARCOT MARIE TOOTH & RELATED NEUROPATHIES

CONSORTIUM (CMTR)

1400-1430 Beyond Mendelian Genomics: the Expanding

Concepts of Heredity in CMT

Stephan Zuchner

Maryland EF

1430-1600 Oral Platform Presentations

Maryland EF

1600-1630 Coffee Break

1630-1700 Structural Variation Causing Inherited

Neuropathies: a paradigm for genomic

organisation, chromatin interactions and

gene dysregulation

Marina Kennerson

Maryland EF

1700-1800 Platform Presentations

Maryland EF

1400-1430 PMP22 antisense oligonucleotides in rodent

models of the Charcot-Marie-Tooth disease

type 1A duplication.

John Svaren

Maryland EF

1430-1600 Oral Platform Presentations

Maryland EF

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Overview on lesson learnt from novel

therapies for hereditary ATTR-neuropathy

Teresa Coelho

Maryland EF

1700-1800 Platform Presentations

Maryland EF

Maryland Foyer

SUNDAY, 22 JULY Diabetes Consortium

MONDAY, 23 JULY

Diabetes Consortium

SUNDAY, 22 LY

1400-1415

1415-1435

1435-1455

1455-1515

1515-1535

Introduction to the Diabetic Neuropathy

Consortium

Christopher Gibbons

Watertable Ballroom

Keystone Target Talks

Obesity Mechanisms as a Targetable

Endpoint in Diabetic Neuropathy

Doug Wright

Watertable Ballroom

Keystone Target Talk- (Lipids and

Neuropathy)

Mark Yorek

Watertable Ballroom

Nox5 as a Therapeutic Target

Stephanie Eid

Watertable Ballroom

Stem Cells as a Potential Treatment in

Dia-betic Neuropathy

Nakamura

Watertable Ballroom

1535-1600 Muscarinic Receptors as a Targetable

End-point in Diabetic Neuropathy

Paul Fernyough

Watertable Ballroom

1600-1630

1630-1700

Coffee Break

Maryland Foyer

Insulin Signaling Pathways as a Potential

Therapeutic Target in DPN

Doug Zochodne

Watertable Ballroom

1700-1730 Oral Platform Presentations

Watertable Ballroom

1730-1800 Oral Poster Presentations

Watertable Ballroom

1400-1430

1430-1500

Moderated Panel Debate Neurophysiology

Endpoint Talks (EMG, QST, Autonomic )

Vera Bril, James Russell, Amanda Peltier

Moderating: Rob Singleton

Watertable Ballroom

Moderated Panel Debate: Structural

Endpoint Talks (CCM, skin biopsy, sural

nerve biopsy)

Rayaz Malik, Michael Polydefkis and Gordon

Smith

Watertable Ballroom

1500-1520 Perspective on endpoints

Eva Feldman and Roy Freeman

Watertable Ballroom

1520-1540 What’s new in DLRPN

Jim Dyck

Watertable Ballroom

1540-1600 What’s new in TIND

Christopher Gibbons

Watertable Ballroom

1600-1630 Coffee Break

Maryland Foyer

1630-1700 Diabetic Peripheral Neuropathy and the

Opioid Crisis

Brian Callaghan

Watertable Ballroom

1700-1730 Oral Platform Presentations

Watertable Ballroom

1730-1800 Oral Poster Presentations

Watertable Ballroom