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RNA and Protein RNA and Protein SynthesisSynthesis
12-3
GenesGenes
GenesGenes are coded DNA instruction are coded DNA instruction that control the production of that control the production of proteins within the cellproteins within the cell
the first step in decoding the the first step in decoding the message of DNA is copy part of the message of DNA is copy part of the nucleotide sequence from DNA to nucleotide sequence from DNA to RNARNA
Structure of RNAStructure of RNA
Almost the same as DNA – they are Almost the same as DNA – they are long chains of nucleotides – sugar, long chains of nucleotides – sugar, phosphate and nitrogen basephosphate and nitrogen base
3 main differences3 main differences– Different sugar Different sugar
DNA = deoxyrobose, RNA = riboseDNA = deoxyrobose, RNA = ribose
– DNA is a double helix, RNA is a single DNA is a double helix, RNA is a single strandstrand
– RNA has Uracil (U) instead of Thymine (T)RNA has Uracil (U) instead of Thymine (T)
Types of RNATypes of RNA
mRNAmRNA – (messenger) RNA molecule – (messenger) RNA molecule that carries copies of instructions from that carries copies of instructions from a gene to the ribosomea gene to the ribosome
tRNAtRNA – (transfer) type of RNA molecule – (transfer) type of RNA molecule that transfers each amino acid to the that transfers each amino acid to the ribosome ribosome
rRNArRNA – (ribosomal) type of RNA that – (ribosomal) type of RNA that helps make up ribosomes helps make up ribosomes
DNA vs RNADNA vs RNA
Protein SynthesisProtein Synthesis
Two main stepsTwo main steps
Transcription Transcription – Takes place in the nucleusTakes place in the nucleus
TranslationTranslation– Takes place at the ribosomesTakes place at the ribosomes
TranscriptionTranscription
TranscriptionTranscription is the copying of the is the copying of the information from DNA to mRNAinformation from DNA to mRNA
RNA polymeraseRNA polymerase is an enzyme that binds is an enzyme that binds to DNA and separates the DNA strands. to DNA and separates the DNA strands. Then it uses one strand of DNA as a Then it uses one strand of DNA as a template to make nucleotides of RNAtemplate to make nucleotides of RNA
The enzyme will only bind to a part of The enzyme will only bind to a part of the DNA know as a the DNA know as a promoterpromoter
TranscriptionTranscription
The Genetic CodeThe Genetic Code
Proteins get made by joining Proteins get made by joining together amino acids into long chains together amino acids into long chains called polypeptidescalled polypeptides
The language that RNA uses to The language that RNA uses to determine the amino acid sequence determine the amino acid sequence is called the genetic codeis called the genetic code
Every 3 nitrogen bases is called a Every 3 nitrogen bases is called a codoncodon or a “word” or a “word”
Each codon is a code for a different Each codon is a code for a different amino acidamino acid
TranslationTranslation
TranslationTranslation is when the cell uses the is when the cell uses the information on the RNA to produce information on the RNA to produce proteinsproteins
mRNA leaves the nucleus and mRNA leaves the nucleus and attaches to a ribosomeattaches to a ribosome
tRNA will bring amino acids to the tRNA will bring amino acids to the ribosomeribosome
AnticodonAnticodons on the tRNA will attach to s on the tRNA will attach to the codon of mRNA linking the amino the codon of mRNA linking the amino acids together in the correct orderacids together in the correct order
protein synthesis video