Ringkasan Abstract dan Introduction

IntroductionHydroxyapatite [Ca10(PO4)6(OH)2; HA] has been widely investigated as a bone

substitute, because it has been shown to form a direct bond with adjacent hard tissue [1–6]. Current methods of preparing HA range from an aqueous solution [7–9], solid-state reaction [10], to hydrothermal methods [11]. Coralline HA (CHA), prepared by the hydrothermal conversion of marine coral, has been used extensively in clinical applications in recent years [12]. conversion of the calcium carbonate (aragonite) skeleton of the marine coral Porites into HA, both with and without the use of the mineralizer KH2PO4,

Abstract X-ray diffraction (XRD) analysis, Fourier transform infrared (FTIR) spectroscopy and

scanning electron microscopy (SEM) were employed to characterize the exchange process. The complete conversion was achieved after 10 and 17 days, respectively, with and without the mineralizer. When the mineralizer was present, the exchange process involved only the direct conversion of aragonite into HA. Without the presence of the mineralizer, there were, in addition, intermediary conversions of aragonite into calcite and calcite into b-tricalcium phosphate (b-TCP).