Ralstonia solanacearum UW551 in planta and in rich …mbio.asm.org/content/suppl/2012/07/11/mBio.00114-12.DCSupplement… · Supplemental Table1A: Expression patterns of Ralstonia

Supplemental Table1A: Expression patterns of Ralstonia solanacearum UW551 in planta and in rich mediumSequence ID AE-value 28 IP AE-value 28 CPG Fold change Change P-value UW551 locus tag Ortholog? Rs Core gene? Gene name Gene description638718745 12.58182987 10.79722245 3.8 up 0.00182 RRSL_04596 o c Hypothetical Protein638718746 12.48300487 9.021372449 12.153 up 0.000276 RRSL_04597 o c Nitrate/nitrite sensor protein narX( EC:2.7.3.- )638718752 11.69940487 8.945472449 7.441 up 0.00729 RRSL_04603 o c Respiratory nitrate reductase alpha chain( EC:1.7.99.4 )638718755 11.57525487 9.104922449 6.113 up 0.0019 RRSL_04606 o c Nitrite extrusion protein638718757 12.16172987 8.951022449 10.213 up 0.000437 RRSL_04608 o c Anaerobic ribonucleoside-triphosphate reductase( EC:1.17.4.2 )638718758 10.35785487 7.755947449 6.697 up 0.00186 RRSL_04609 o c Pyruvate formate-lyase activating enzyme( EC:1.97.1.4 )638718810 10.25670487 9.196847449 2.299 up 0.0328 RRSL_04662 o c Cardiolipin synthetase( EC:2.7.8.- )638718907 8.342379869 7.430197449 2.076 up 0.0157 RRSL_04765 o c Cytochrome O ubiquinol oxidase subunit III( EC:1.10.3.- )638718908 8.994404869 8.024622449 2.16 up 0.00283 RRSL_04767 o c Cytochrome c oxidase polypeptide I( EC:1.9.3.1 )638718909 9.060454869 7.782322449 2.675 up 0.00826 RRSL_04768 o c Hypothetical Protein( EC:1.9.3.1 )638718935 10.25605487 8.470897449 3.802 up 0.0417 RRSL_04390 o c rbsC RbsC638718945 12.72305487 10.79569745 4.196 up 0.000838 RRSL_04400 o c Carboxypeptidase S1( EC:3.4.16.6 )638718951 11.08910487 10.18369745 2.066 up 0.00622 RRSL_04407 o c hypothetical protein638718990 12.33040487 11.08462245 2.616 up 0.0135 RRSL_04448 o c hypothetical protein638719068 9.703854869 8.359647449 2.8 up 0.014 RRSL_04529 o c hypothetical protein638719087 14.85327987 11.73617245 9.571 up 0.00000682 RRSL_04548 o c hypothetical protein638719109 9.826229869 8.323847449 3.125 up 0.00164 RRSL_04571 o c Alkyl hydroperoxide reductase C22( EC:1.6.4.- )638719157 10.40872987 9.326647449 2.335 up 0.0101 RRSL_04307 o c HlyD family secretion protein638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719173 9.372379869 8.167697449 2.542 up 0.0482 RRSL_04324 o c Transposase638719205 11.29360487 9.647947449 3.451 up 0.0103 RRSL_04358 o c Enoyl-[acyl-carrier protein] reductase (NADH)( EC:1.3.1.9 )638719230 13.78610487 10.73302245 9.156 up 0.000259 RRSL_04386 o c Hypothetical Protein638719277 12.27905487 10.96217245 2.748 up 0.000902 RRSL_04096 o c Molybdopterin-guanine dinucleotide biosynthesis protein B638719308 8.723454869 7.469522449 2.631 up 0.0195 RRSL_04128 o c Hypothetical Protein638719309 12.80550487 10.94884745 3.995 up 0.000526 RRSL_04129 o c Transporter638719332 8.423679869 7.545147449 2.028 up 0.00697 RRSL_04156 o c Apolipoprotein N-acyltransferase( EC:2.3.1.- )638719344 11.10445487 9.495572449 3.364 up 0.000139 RRSL_04169 o c Outer membrane porin protein 32 precursor638719349 10.56530487 9.237322449 2.769 up 0.0318 RRSL_04174 o c Hypothetical Protein638719352 11.89860487 8.641497449 10.547 up 0.00243 RRSL_04177 o c Flavohemoprotein / Dihydropteridine reductase / Nitric oxide dioxygenase( EC:1.14.12.17,EC:1.6.99.7 )638719354 10.96897987 9.512222449 3.028 up 0.00291 RRSL_04180 o c Probable transmembrane transporter, MFS family638719367 9.513629869 8.328497449 2.508 up 0.0454 RRSL_04193 o c Probable transmembrane methyl-accepting chemotaxis protein638719489 9.944654869 8.887222449 2.296 up 0.041 RRSL_03869 o c UDP-2,3-diacylglucosamine hydrolase( EC:3.6.1.- )638719585 12.59870487 11.31852245 2.679 up 0.0136 RRSL_03966 o c Transcriptional regulator, MarR family638719588 9.305429869 8.031247449 2.668 up 0.0303 RRSL_03970 o c Probable transmembrane methyl-accepting chemotaxis protein638719594 12.04082987 8.264172449 15.119 up 0.000385 RRSL_03976 o c Alcohol dehydrogenase( EC:1.1.1.1 )638719622 13.23822987 11.41102245 3.914 up 0.00159 RRSL_04004 o c serine protease638719624 10.82227987 9.361722449 3.036 up 0.00519 RRSL_04006 o c hypothetical protein638719715 11.51040487 8.888522449 6.79 up 0.000398 RRSL_03499 o c Flavodoxin638719885 8.496129869 7.540322449 2.139 up 0.0159 RRSL_03584 o c Chloride channel protein638719886 11.95850487 9.565997449 5.792 up 0.000905 RRSL_03585 o c Transcriptional regulator, MarR family638719892 11.72660487 10.42774745 2.714 up 0.00416 RRSL_03590 o c Permease638719894 13.68142987 12.52762245 2.454 up 0.0032 RRSL_03592 o c Oxidoreductase( EC:1.1.1.- )638719932 9.308429869 8.212397449 2.358 up 0.00239 RRSL_03632 o c Formate hydrogenlyase subunit 6638719935 10.01670487 8.255147449 3.74 up 0.00246 RRSL_03635 o c Formate dehydrogenase (cytochrome b) major subunit( EC:1.2.2.1 )638719936 10.18202987 8.319272449 4.012 up 0.00191 RRSL_03636 o c Formate dehydrogenase (cytochrome b) iron-sulfur subunit( EC:1.2.2.1 )638719937 9.368654869 8.026547449 2.796 up 0.0139 RRSL_03637 o c Hypothetical Protein638719946 9.553529869 7.707197449 3.966 up 0.021 RRSL_03646 o c Hypothetical Protein638719996 12.15715487 10.49009745 3.503 up 0.00108 RRSL_02682 o c Pectate lyase( EC:4.2.2.2 )638720030 10.76117987 9.866747449 2.05 up 0.00314 RRSL_02642 o c marC MarC

638720215 12.97550487 8.178022449 30.678 up 0.000229 RRSL_03378 o c Sucrose-6-phosphate hydrolase( EC:3.2.1.26 )638720216 12.66805487 8.134222449 25.554 up 0.0002 RRSL_03379 o c PTS system, sucrose-specific IIBC component( EC:2.7.1.69 )638720381 9.871304869 8.949847449 2.089 up 0.0124 RRSL_02962 o c 4-aminobutyrate aminotransferase( EC:2.6.1.19 )638720435 9.042279869 7.434747449 3.361 up 0.0079 RRSL_03197 o c Imidazolonepropionase( EC:3.5.2.7 )638720437 12.17532987 9.712147449 6.083 up 0.00339 RRSL_03199 o c Histidine ammonia-lyase( EC:4.3.1.3 )638720438 11.80462987 10.06604745 3.681 up 0.00422 RRSL_03200 o c Urocanate hydratase( EC:4.2.1.49 )638720475 10.41017987 8.863222449 3.223 up 0.000908 RRSL_03241 o c Hypothetical Protein638720589 8.847129869 7.469697449 2.866 up 0.0121 RRSL_02903 o c hypothetical protein638720591 11.43380487 9.113522449 5.509 up 0.00747 RRSL_02905 o c hypothetical protein638720592 9.527504869 8.516822449 2.222 up 0.0106 RRSL_02906 o c hypothetical protein638720610 13.10247987 11.99869745 2.37 up 0.0109 RRSL_02785 o c Integral membrane protein638720613 12.63112987 10.47119745 4.93 up 0.035 RRSL_02788 o c fucose/mannose-binding lectin638720619 12.28130487 7.999922449 21.452 up 0.00114 RRSL_02794 o c Coproporphyrinogen oxidase, anaerobic( EC:1.- )638720629 10.32337987 8.986522449 2.786 up 0.04 RRSL_02805 o c Transcriptional regulator, GntR family638720630 10.30752987 7.825647449 6.162 up 0.0499 RRSL_02806 o c C4-dicarboxylate transport protein638720634 9.895854869 8.844272449 2.286 up 0.000623 RRSL_02810 o c Hypothetical Protein638720636 11.14322987 8.881672449 5.289 up 0.00287 RRSL_02812 o c Hypothetical Protein638720697 11.98345487 9.241272449 7.381 up 0.0249 RRSL_02730 o c Hypothetical Protein638720699 9.005979869 8.056222449 2.13 up 0.00713 RRSL_02732 o c Hypothetical Protein638720739 12.13475487 9.953447449 5.003 up 0.0021 RRSL_02771 o c Iron(III)-binding protein638720740 11.37547987 8.939272449 5.97 up 0.000593 RRSL_02772 o c sfuB SfuB638720741 11.51202987 9.520447449 4.387 up 0.00113 RRSL_02773 o c sfuC SfuC638720897 10.96590487 7.526897449 11.964 up 0.0239 RRSL_02385 o c Transcriptional regulators, LysR family638720907 12.90612987 11.80629745 2.364 up 0.0226 RRSL_02395 o c Hypothetical Protein638720960 9.968804869 8.813572449 2.457 up 0.00633 RRSL_02178 o c pstA PstA638720961 10.05705487 9.058822449 2.203 up 0.0182 RRSL_02179 o c pstC PstC638720978 11.70025487 9.919822449 3.789 up 0.00151 RRSL_02197 o c Hypothetical Protein638720979 10.67065487 8.339447449 5.551 up 0.000401 RRSL_02198 o c DnaK suppressor protein638720980 11.63472987 9.666047449 4.318 up 0.00131 RRSL_02199 o c Hypothetical Protein638720981 14.01155487 11.53029745 6.16 up 0.000699 RRSL_02200 o c Hypothetical Protein638720982 9.439729869 8.276972449 2.469 up 0.0187 RRSL_02201 o c Alcohol dehydrogenase( EC:1.1.1.1 )638720983 11.42525487 7.950997449 12.26 up 0.00111 RRSL_02202 o c Hypothetical Protein638720984 11.79600487 10.19579745 3.344 up 0.000913 RRSL_02203 o c Hypothetical membrane spanning protein638721035 10.35375487 8.817697449 3.199 up 0.00567 RRSL_03106 o c pglA PglA( EC:3.2.1.15 )638721047 12.74542987 7.948597449 30.665 up 0.000344 RRSL_02442 o c popB PopB638721049 9.912754869 7.837897449 4.647 up 0.0124 RRSL_00024 o c hrcC HrcC638721050 11.73442987 7.951822449 15.182 up 0.000568 RRSL_10003 o c hrpB HrpB638721051 12.91732987 10.77619745 4.866 up 0.000325 RRSL_00525 o c hrcT HrcT638721052 10.33767987 8.408872449 4.2 up 0.0025 RRSL_00524 o c hrpD HrpD638721053 11.40110487 8.504022449 8.217 up 0.00122 RRSL_00523 o c hrcN HrcN638721054 8.930604869 7.575097449 2.822 up 0.0274 RRSL_00522 o c hrpF HrpF638721055 9.656229869 7.456147449 5.069 up 0.0076 RRSL_00520 o c hrpH HrpH638721056 10.20620487 7.943347449 5.294 up 0.0109 RRSL_00519 o c hrcJ HrcJ638721057 11.59410487 7.707722449 16.314 up 0.000205 RRSL_00518 o c hrpK HrpK638721058 8.761629869 7.500222449 2.644 up 0.00392 RRSL_00517 o c hrcU HrcU638721059 9.157654869 7.989747449 2.478 up 0.0277 RRSL_00516 o c hrcV HrcV638721061 14.12450487 10.14932245 17.35 up 0.0000784 RRSL_00514 o c hrcQ HrcQ638721062 12.09645487 8.741497449 11.287 up 0.000166 RRSL_00513 o c hrcR HrcR638721063 10.61270487 8.428172449 5.014 up 0.00165 RRSL_00512 o c hrcS HrcS638721064 11.66750487 9.004772449 6.985 up 0.00123 RRSL_00511 o c hrpV HrpV638721065 12.46887987 9.918672449 6.461 up 0.00153 RRSL_00510 o c hrpW HrpW638721066 13.18190487 9.945972449 10.393 up 0.00018 RRSL_00509 o c hrpX HrpX638721067 16.50682987 10.72299745 60.78 up 0.00000202 RRSL_00508 o c hrpY HrpY638721068 13.29675487 9.501472449 15.316 up 0.000126 RRSL_00507 o c hrpZ HrpZ638721069 10.99880487 6.995247449 17.694 up 0.000118 RRSL_00506 o c hpaB HpaB638721070 14.00817987 9.661522449 22.445 up 0.0000508 RRSL_00505 o c hrpG HrpG638721071 9.838679869 8.205672449 3.421 up 0.00181 RRSL_00504 o c prhJ PrhJ

638721180 10.80692987 9.374872449 2.976 up 0.0119 RRSL_02160 o c Myo-inositol uptake ATP-binding protein638721181 12.07842987 10.57612245 3.125 up 0.00343 RRSL_02161 o c Myo-inositol transport system permease protein638721397 13.61280487 8.909472449 28.74 up 0.000614 RRSL_01886 o c Outer membrane protein638721432 10.01532987 9.138422449 2.025 up 0.0105 RRSL_01921 o c Probable transmembrane methyl-accepting chemotaxis protein638721448 11.18517987 7.916297449 10.633 up 0.0345 RRSL_01938 o c Ferredoxin--NAD(P)(+) reductase( EC:1.18.1.- )638721542 12.07925487 10.93117245 2.444 up 0.00313 RRSL_01690 o c Hypothetical Protein638721675 13.65872987 12.51197245 2.442 up 0.0297 RRSL_01193 o c Hypothetical Protein638721688 12.00450487 8.670197449 11.127 up 0.000129 RRSL_01625 o c Hypothetical Protein638721732 14.19810487 12.88852245 2.734 up 0.00262 RRSL_01671 o c Hypothetical Protein638721750 11.01600487 10.15287245 2.006 up 0.0427 RRSL_01547 o c Probable molybdenum-pterin binding protein638721753 8.879429869 7.905022449 2.167 up 0.0398 RRSL_01550 o c cysT CysT638721763 13.34297987 9.210147449 19.353 up 0.000104 RRSL_01562 o c Leucine-rich repeat family protein638721765 13.29780487 11.81907245 3.074 up 0.00232 RRSL_01564 o c Isocitrate lyase( EC:4.1.3.1 )638721785 15.49682987 12.58712245 8.29 up 0.000696 RRSL_01586 o c Hypothetical Protein638721865 11.42575487 9.334247449 4.701 up 0.00119 RRSL_01397 o c Iron-Sulfur 4Fe-4S Ferredoxin638721866 13.10700487 9.609297449 12.461 up 0.00109 RRSL_01398 o c cytochrome c oxidase, diheme subunit, membrane-bound( EC:1.9.3.1 )638721867 10.61850487 7.358497449 10.568 up 0.00059 RRSL_01399 o c Hypothetical Protein638721868 11.19480487 8.757497449 5.975 up 0.0079 RRSL_01400 o c cytochrome c oxidase, monoheme subunit, membrane-bound( EC:1.9.3.1 )638721869 12.49605487 10.38152245 4.777 up 0.00042 RRSL_01401 o c Cytochrome c oxidase polypeptide I( EC:1.9.3.1 )638721870 12.22750487 9.744897449 6.165 up 0.000256 RRSL_01402 o c fixS FixS638721871 8.493129869 7.558472449 2.108 up 0.039 RRSL_01403 o c Nitrogen fixation protein fixI (E1-E2 type cation ATPase fixI)( EC:3.6.3.- )638721968 8.959179869 8.040072449 2.086 up 0.0176 RRSL_01118 o c Hypothetical Protein638721969 10.69945487 8.836097449 4.014 up 0.00386 RRSL_01119 o c Nitrite reductase [NAD(P)H] large subunit( EC:1.7.1.4 )638722085 10.30180487 8.475497449 3.912 up 0.0017 RRSL_01283 o c Hypothetical Protein638722104 9.342354869 8.053072449 2.696 up 0.000843 RRSL_01030 o c Glucarate dehydratase( EC:4.2.1.40 )638722105 10.49302987 8.834747449 3.482 up 0.00577 RRSL_01031 o c Glucarate/galactarate transporter638722175 11.50275487 10.12022245 2.876 up 0.00272 RRSL_01504 o c Tryptophan 2,3-dioxygenase( EC:1.13.11.11 )638722176 10.48130487 9.363847449 2.393 up 0.00157 RRSL_01505 o c L-kynurenine hydrolase( EC:3.7.1.3 )638722179 10.63292987 9.459647449 2.487 up 0.0281 RRSL_01508 o c Hypothetical Protein638722193 11.62560487 10.49414745 2.416 up 0.0118 RRSL_01522 o c Hypothetical Protein638722209 9.351554869 8.099772449 2.627 up 0.00374 RRSL_01292 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638722220 9.181304869 8.256522449 2.094 up 0.0032 RRSL_01304 o c Hypothetical Protein638722221 11.95992987 10.45489745 3.131 up 0.00323 RRSL_01305 o c ABC transporter substrate-binding protein638722222 12.48262987 11.06817245 2.94 up 0.0414 RRSL_01306 o c ABC transporter permease protein638722227 15.88800487 14.89267245 2.199 up 0.00195 RRSL_01312 o c Hypothetical Protein638722228 16.00410487 14.75259745 2.626 up 0.000124 RRSL_01313 o c Hypothetical Protein638722264 10.71772987 8.537822449 4.998 up 0.00259 RRSL_01478 o c Transporter638722335 11.01695487 9.772847449 2.613 up 0.00491 RRSL_00811 o c Kup system potassium uptake protein638722382 10.62645487 9.515222449 2.383 up 0.0107 RRSL_00974 o c Hypothetical Protein638722416 9.421804869 8.273097449 2.445 up 0.0176 RRSL_00688 o c probable transmembrane methyl-accepting chemotaxis protein638722417 9.552404869 8.637297449 2.08 up 0.0117 RRSL_00689 o c Mg(2+) transport ATPase protein C638722418 11.48920487 9.754372449 3.671 up 0.000116 RRSL_00690 o c Nucleoside-diphosphate-sugar epimerases638722419 8.664829869 7.633372449 2.255 up 0.00378 RRSL_00691 o c CoxI protein638722421 10.43005487 8.573322449 3.995 up 0.0057 RRSL_00694 o c ATP-dependent protease subunit638722424 9.058204869 7.937297449 2.399 up 0.0079 RRSL_00697 o c Carbon monoxide oxygenase (cytochrome b-561) large subunit( EC:1.2.2.4 )638722425 12.18870487 10.26194745 4.194 up 0.000318 RRSL_00698 o c Carbon monoxide oxygenase (cytochrome b-561) iron-sulfur subunit( EC:1.2.2.4 )638722426 15.21355487 13.90782245 2.727 up 0.0134 RRSL_00699 o c Hypothetical Protein638722459 12.61185487 9.080922449 12.751 up 0.0111 RRSL_00910 o c Glucarate dehydratase( EC:4.2.1.40 )638722460 10.47345487 9.497297449 2.17 up 0.0103 RRSL_00909 o c Transcriptional regulator, GntR family638722562 9.126904869 8.189997449 2.111 up 0.0274 RRSL_00668 o c dppB DppB638722574 10.91205487 9.893397449 2.235 up 0.00889 RRSL_00680 o c Probable transmembrane methyl-accepting chemotaxis protein638722662 10.07655487 9.077422449 2.205 up 0.0041 RRSL_00531 o c Leucine-rich repeat family protein638722663 10.51120487 8.690222449 3.897 up 0.000952 RRSL_00532 o c cd00116, LRR_RI, Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily.638722665 9.165729869 7.761147449 2.92 up 0.00203 RRSL_00534 o c Pyruvate dehydrogenase E1 component beta subunit( EC:1.2.4.1 )638722666 9.174554869 7.794497449 2.871 up 0.00168 RRSL_00535 o c Pyruvate dehydrogenase E1 component alpha subunit( EC:1.2.4.1 )638722692 10.32605487 9.180722449 2.44 up 0.0104 RRSL_00754 o c Probable chemotaxis response regulator protein (cheY2)638722710 8.455729869 7.517097449 2.114 up 0.0147 RRSL_00650 o c Probable chemotaxis phosphatase (cheZ1)

638722711 8.895229869 7.979672449 2.08 up 0.0139 RRSL_00651 o c Probable chemotaxis response regulator protein (cheY1)638722727 12.02495487 11.02942245 2.199 up 0.0111 RRSL_00801 o c livG LivG638722728 10.25165487 9.223022449 2.25 up 0.00261 RRSL_00802 o c livF LivF638722729 13.59040487 11.83519745 3.724 up 0.000122 RRSL_00803 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638722730 12.05892987 10.65084745 2.927 up 0.00156 RRSL_00804 o c livH LivH638722731 11.84330487 10.75407245 2.347 up 0.0121 RRSL_00806 o c livM LivM638722737 12.49955487 10.62642245 4.041 up 0.0131 RRSL_00596 o c hypothetical protein638722738 14.23417987 12.64677245 3.315 up 0.000998 RRSL_00597 o c VirK protein638722830 14.92657987 13.95222245 2.167 up 0.0097 RRSL_00348 o c Ferredoxin--NADP reductase( EC:1.18.1.2 )638722869 13.25345487 11.80494745 3.01 up 0.00406 RRSL_00617 o c alpha-ketoglutarate permease, kgtP2638723117 11.67075487 10.38669745 2.686 up 0.0117 RRSL_00089 o c Hypothetical Protein638723144 10.74945487 9.749472449 2.206 up 0.0211 RRSL_00036 o c Transcriptional regulator, GntR family638718743 9.741204869 7.877497449 4.014 up 0.0129 RRSL_04594 o Asparagine synthetase (glutamine-hydrolyzing)( EC:6.3.5.4 )638718747 10.08815487 7.991047449 4.72 up 0.0194 RRSL_04598 o Molybdopterin-guanine dinucleotide biosynthesis protein B638718748 12.65982987 8.325172449 22.259 up 0.000701 RRSL_04599 o Respiratory nitrate reductase gamma chain( EC:1.7.99.4 )638718749 10.43342987 7.688372449 7.396 up 0.00621 RRSL_04600 o Respiratory nitrate reductase delta chain( EC:1.7.99.4 )638718756 9.564879869 7.714447449 3.978 up 0.00715 RRSL_04607 o Nitrite extrusion protein638718759 9.707329869 7.090247449 6.768 up 0.00272 RRSL_04610 o Hypothetical Protein638718760 9.519204869 7.469147449 4.568 up 0.00298 RRSL_04611 o Hypothetical Protein638718761 9.939629869 7.360522449 6.592 up 0.000743 RRSL_04612 o sterol binding protein638718762 10.16307987 7.641372449 6.335 up 0.00312 RRSL_04613 o Putative protease yhbV precursor( EC:3.4.- )638718763 10.99412987 8.311822449 7.081 up 0.000998 RRSL_04614 o Putative protease yhbU precursor( EC:3.4.- )638718768 9.929579869 8.846897449 2.336 up 0.0328 RRSL_04619 o Hypothetical protein638718770 10.99605487 9.444497449 3.233 up 0.0113 RRSL_04621 o Hypothetical Protein638718781 10.41977987 9.495522449 2.093 up 0.0125 RRSL_04632 o Hypothetical Protein638718804 8.941029869 7.951472449 2.19 up 0.0115 RRSL_04655 o Hypothetical Protein638718814 12.68337987 10.89194745 3.818 up 0.000323 RRSL_04666 o Cyanide-insensitive cytochrome bd-type quinol oxidase subunit I( EC:1.10.3.- )638718815 10.55277987 8.236097449 5.495 up 0.00347 RRSL_04667 o Cyanide-insensitive cytochrome bd-type quinol oxidase subunit II( EC:1.10.3.- )638718818 10.60845487 9.529347449 2.33 up 0.00995 RRSL_04670 o Hypothetical Protein638718853 13.36745487 12.33159745 2.261 up 0.00536 RRSL_04709 o Hypothetical cytosolic protein638718855 9.211204869 7.697822449 3.149 up 0.0233 RRSL_04711 o Methylamine utilization protein mauG precursor638718871 9.565729869 8.269272449 2.709 up 0.0133 RRSL_04728 o Hypothetical Protein638718877 11.47462987 9.602472449 4.038 up 0.00728 RRSL_04734 o Hypothetical Protein638718918 13.38712987 8.818622449 26.176 up 0.000627 RRSL_04777 o Nodulation protein NOLX638718926 15.99235487 13.71969745 5.33 up 0.000184 RRSL_04787 o Hypothetical Protein638718931 11.10257987 10.19102245 2.075 up 0.0135 RRSL_04792 o Hypothetical Protein638718976 15.34282987 14.23854745 2.371 up 0.00331 RRSL_04432 o hypothetical protein638719012 9.789054869 7.462172449 5.534 up 0.0236 RRSL_04471 o probable transmembrane protein638719086 11.80112987 8.987322449 7.757 up 0.00176 RRSL_04547 o probable conserved hypothetical protein638719278 13.27562987 11.42504745 3.978 up 0.0006 RRSL_04097 o Avirulence D protein638719279 11.17832987 9.812097449 2.844 up 0.000649 RRSL_04098 o Phosphoglycolate phosphatase( EC:3.1.3.18 )638719311 11.38370487 9.281572449 4.736 up 0.0323 RRSL_04130 o Hypothetical Protein638719369 11.53922987 10.29842245 2.607 up 0.00351 RRSL_04195 o Hypothetical membrane spanning protein638719530 8.885929869 7.955447449 2.102 up 0.0125 RRSL_03910 o Nodulation protein N638719562 16.09665487 14.67082245 2.963 up 0.000151 RRSL_03943 o hypothetical protein638719564 13.81215487 11.86157245 4.264 up 0.0000625 RRSL_03945 o hypothetical protein638719567 11.43390487 7.589747449 15.843 up 0.000177 RRSL_03948 o Oxidoreductase ucpA( EC:1.- )638719568 10.32847987 7.327872449 8.829 up 0.00138 RRSL_03949 o Isopenicillin N epimerase( EC:5.- )638719569 9.847604869 8.148247449 3.582 up 0.0199 RRSL_03950 o NADPH-dependent glutamate synthase beta chain and related oxidoreductases638719570 10.38200487 7.771172449 6.738 up 0.00424 RRSL_03951 o Tryptophan 2,3-dioxygenase( EC:1.13.11.11 )638719600 10.84797987 9.644797449 2.54 up 0.00564 RRSL_03982 o Pyruvate-flavodoxin oxidoreductase( EC:1.- )638719742 9.962404869 8.855197449 2.376 up 0.0112 RRSL_03527 o Hypothetical Protein638719861 9.823029869 8.627297449 2.526 up 0.000825 RRSL_03559 o Hypothetical Protein638719884 9.525454869 8.071022449 3.023 up 0.00232 RRSL_03583 o Hypothetical Protein638719934 11.56065487 9.929397449 3.417 up 0.000709 RRSL_03634 o Hypothetical Protein638719938 9.762904869 8.412897449 2.812 up 0.0168 RRSL_03638 o Formate dehydrogenase, cytochrome B556 subunit( EC:1.2.2.1 )638719939 9.884554869 8.775147449 2.38 up 0.0131 RRSL_03639 o Hypothetical Protein

638720148 9.107029869 8.176222449 2.103 up 0.0072 RRSL_03669 o Probable transmembrane methyl-accepting chemotaxis protein638720185 13.12607987 10.21032245 8.324 up 0.000411 RRSL_03707 o Vanillate O-demethylase oxygenase subunit( EC:1.14.13.82,EC:1.2.3.12 )638720186 9.977054869 8.525897449 3.016 up 0.0091 RRSL_03708 o Vanillate O-demethylase oxidoreductase subunit( EC:1.2.3.12 )638720188 12.53782987 10.32602245 5.11 up 0.000934 RRSL_03710 o Hypothetical Protein638720192 8.733779869 7.529372449 2.542 up 0.0476 RRSL_03714 o transkriptions-aktivator-protein638720204 11.68210487 10.12699745 3.241 up 0.0212 RRSL_03366 o Omega-amino acid--pyruvate aminotransferase( EC:2.6.1.18 )638720209 12.59875487 9.295922449 10.886 up 0.000107 RRSL_03371 o Hypothetical Protein638720210 11.31007987 8.596097449 7.238 up 0.000182 RRSL_03372 o Ferrichrome-iron receptor638720211 12.24600487 9.349672449 8.213 up 0.000909 RRSL_03374 o Fructokinase( EC:2.7.1.4 )638720212 12.01470487 8.387497449 13.631 up 0.000526 RRSL_03375 o Hypothetical Protein

638720213 10.74825487 7.620372449 9.643 up 0.0051 RRSL_03376 oPhosphoenolpyruvate-protein phosphotransferase / Phosphocarrier protein HPr / PTS system, glucose-specific IIA subunit( EC:2.7.1.69,EC:2.7.3.9 )

638720214 11.42665487 7.907322449 12.649 up 0.00416 RRSL_03377 o Maltoporin638720217 11.99102987 9.975822449 4.459 up 0.0137 RRSL_03380 o Transcriptional regulator, LacI family638720272 9.052029869 7.035097449 4.464 up 0.00895 RRSL_03438 o Hypothetical Protein638720291 11.46415487 10.16454745 2.715 up 0.00195 RRSL_03035 o HdeD protein638720319 12.28012987 9.667897449 6.745 up 0.0000823 RRSL_03065 o Hypothetical Protein638720321 12.04587987 11.13689745 2.071 up 0.0333 RRSL_03067 o Hypothetical Protein638720322 9.878454869 8.338922449 3.207 up 0.0209 RRSL_03068 o Hypothetical Protein638720477 9.982329869 8.615472449 2.845 up 0.00958 RRSL_03243 o Hypothetical Protein638720507 9.410679869 7.884747449 3.176 up 0.00435 RRSL_02246 o 3-hydroxyisobutyrate dehydrogenase( EC:1.1.1.31 )

638720508 10.27995487 8.600297449 3.534 up 0.006 RRSL_02247 omalonate-semialdehyde dehydrogenase [acylating] / methylmalonate-semialdehyde dehydrogenase (acylating)( EC:1.2.1.18,EC:1.2.1.27 )

638720514 10.44582987 9.220997449 2.578 up 0.0397 RRSL_02253 o Transmembrane transport protein. Major facilitator superfamily.638720524 9.526104869 8.326697449 2.533 up 0.0262 RRSL_02264 o Leucine-rich repeat family protein638720528 11.49990487 9.627297449 4.039 up 0.0051 RRSL_02268 o 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase( EC:2.1.1.14 )638720611 11.99992987 11.11144745 2.042 up 0.0214 RRSL_02786 o Hypothetical Protein638720663 10.35537987 9.329647449 2.246 up 0.00943 RRSL_02843 o conserved hypothetical protein638720800 10.99532987 8.506322449 6.193 up 0.0000872 RRSL_02094 o Hypothetical Protein638720803 12.82935487 11.67562245 2.454 up 0.0204 RRSL_02098 o Flagellar transcriptional activator (flhD)638720804 13.74110487 12.05632245 3.546 up 0.000812 RRSL_02099 o Flagellar transcriptional activator (flhC)638720805 10.08890487 8.444447449 3.448 up 0.00138 RRSL_02100 o Probable chemotaxis motA protein638720806 10.58807987 8.921397449 3.502 up 0.00567 RRSL_02101 o Probable chemotaxis motB protein638720807 9.861604869 8.497972449 2.838 up 0.0131 RRSL_02102 o Probable chemotaxis response regulator protein (cheY)638720808 9.172929869 8.165447449 2.217 up 0.0159 RRSL_02103 o Probable chemotaxis sensor histidine kinase (cheA)638720809 9.113554869 7.998497449 2.389 up 0.00408 RRSL_02104 o Probable chemotaxis coupling protein (cheW)638720814 11.46890487 8.848422449 6.784 up 0.00432 RRSL_02295 o Hypothetical Protein638720815 10.21372987 7.645697449 6.541 up 0.00111 RRSL_02296 o Hypothetical Protein638720816 9.364004869 8.136397449 2.583 up 0.0216 RRSL_02297 o Hypothetical Protein638720819 11.02957987 8.963872449 4.618 up 0.0163 RRSL_02300 o Hypothetical Protein638720830 9.701379869 8.372772449 2.77 up 0.0103 RRSL_02311 o fliH FliH638720831 9.319179869 8.072822449 2.617 up 0.0127 RRSL_02312 o fliG FliG638720833 9.292604869 8.133797449 2.463 up 0.0057 RRSL_02314 o fliE FliE638720834 10.22735487 8.533822449 3.568 up 0.0114 RRSL_02315 o Hypothetical protein638720837 10.91635487 7.886997449 9.007 up 0.00387 RRSL_02318 o fliT FliT638720838 8.940854869 7.295522449 3.451 up 0.0198 RRSL_02319 o fliS FliS638720839 9.757354869 8.369847449 2.886 up 0.00865 RRSL_02320 o fliD FliD638720840 14.89740487 12.38984745 6.273 up 0.00301 RRSL_02321 o fliC FliC638720843 10.15172987 8.805772449 2.804 up 0.00886 RRSL_02324 o fliL FliL638720846 9.658304869 8.469947449 2.514 up 0.0418 RRSL_02327 o fliO FliO638720847 8.643804869 7.564497449 2.331 up 0.0294 RRSL_02328 o fliP FliP638720848 9.821779869 8.393447449 2.969 up 0.00948 RRSL_02329 o fliQ FliQ638720851 8.663629869 7.778622449 2.037 up 0.0243 RRSL_02334 o flgL FlgL638720853 10.82965487 9.670072449 2.464 up 0.0228 RRSL_02336 o flgJ FlgJ638720854 9.482704869 8.381422449 2.366 up 0.0237 RRSL_02337 o flgI FlgI638720856 11.28602987 10.36147245 2.093 up 0.0314 RRSL_02339 o flgG FlgG638720859 11.83580487 10.95057245 2.037 up 0.0118 RRSL_02342 o flgD FlgD

638720860 10.34385487 9.012797449 2.775 up 0.0117 RRSL_02343 o flgC FlgC638720877 10.73872987 9.180472449 3.248 up 0.00186 RRSL_02362 o Cytochrome c oxidase polypeptide I( EC:1.9.3.1 )638720985 12.07647987 10.81177245 2.65 up 0.0115 RRSL_02204 o Hypothetical Protein638720986 14.33472987 12.75302245 3.302 up 0.000833 RRSL_02205 o Hypothetical Protein638720996 11.36565487 10.42949745 2.11 up 0.0123 RRSL_02215 o Hypothetical Protein638721008 10.68055487 9.645247449 2.261 up 0.011 RRSL_02228 o Hypothetical Protein638721026 10.45877987 8.759997449 3.581 up 0.00964 RRSL_03117 o 2-amino-3-ketobutyrate coenzyme A ligase( EC:2.3.1.29 )638721028 9.488879869 7.275397449 5.116 up 0.000928 RRSL_03114 o glnA GlnA( EC:6.3.1.2 )638721029 8.953579869 7.791972449 2.467 up 0.0115 RRSL_03113 o Hypothetical Protein638721036 10.57862987 8.596922449 4.357 up 0.00145 RRSL_03105 o conserved hypothetical protein638721046 14.84807987 8.220272449 109.099 up 0.00000569 RRSL_02443 o popA PopA638721048 13.16620487 9.069147449 18.879 up 0.0000854 RRSL_02441 o popC PopC638721060 10.28105487 7.939622449 5.591 up 0.00167 RRSL_00515 o hpaP HpaP638721073 9.829654869 8.127297449 3.59 up 0.00917 RRSL_00502 o Hypothetical Protein638721173 11.29727987 10.30317245 2.197 up 0.0234 RRSL_02153 o Hypothetical protein638721183 10.12292987 8.773422449 2.811 up 0.0244 RRSL_02163 o IolD PROTEIN638721184 11.00942987 9.667347449 2.796 up 0.00894 RRSL_02164 o IolE protein638721185 11.76535487 10.71072245 2.291 up 0.0181 RRSL_02165 o IolB protein638721190 12.86385487 11.35049745 3.149 up 0.000869 RRSL_02516 o hypothetical protein638721193 12.08942987 10.13414745 4.278 up 0.00011 RRSL_02518 o hypothetical protein638721205 14.37772987 13.16734745 2.552 up 0.00224 RRSL_02532 o Catalase( EC:1.11.1.6 )638721220 12.59557987 11.45489745 2.432 up 0.0265 RRSL_02549 o hypothetical protein638721252 15.16715487 14.27419745 2.048 up 0.0234 RRSL_02458 o Transmembrane LysE-type efflux permease638721567 15.83605487 12.65932245 9.975 up 0.000361 RRSL_01716 o Hypothetical Protein638721575 9.628904869 8.110172449 3.161 up 0.0429 RRSL_01724 o Alcohol dehydrogenase( EC:1.1.1.1 )638721603 12.10997987 10.09547245 4.457 up 0.00566 RRSL_01802 o Atrazine chlorohydrolase( EC:3.8.1.8 )638721604 11.06295487 10.14922245 2.078 up 0.0353 RRSL_01803 o Carboxypeptidase S( EC:3.4.17.4 )638721619 8.382104869 7.519997449 2.005 up 0.00513 RRSL_01819 o Probable transmembrane methyl-accepting chemotaxis protein638721748 10.32625487 8.689122449 3.431 up 0.0429 RRSL_01545 o Alkanesulfonates transport system permease protein638721754 11.20632987 8.747672449 6.064 up 0.0413 RRSL_01551 o cysW CysW638721756 9.139879869 7.569697449 3.275 up 0.00758 RRSL_01554 o Hypothetical Protein638721757 9.593229869 8.287197449 2.727 up 0.0315 RRSL_01555 o Hypothetical Protein638721917 14.62100487 13.58737245 2.258 up 0.00118 RRSL_01378 o Hypothetical Protein638721967 9.237529869 8.037747449 2.534 up 0.00391 RRSL_01117 o Assimilatory nitrate reductase small subunit( EC:1.7.1.2 )638721970 10.64185487 8.993572449 3.458 up 0.00326 RRSL_01120 o Transporter638721971 8.797404869 7.527547449 2.66 up 0.0184 RRSL_01121 o Probable aerotaxis receptor (aer1)638721973 10.35267987 9.138172449 2.56 up 0.0462 RRSL_01123 o Hypothetical Protein638721985 8.276954869 7.388647449 2.042 up 0.00994 RRSL_01136 o Hypothetical Protein638722049 8.288654869 7.285647449 2.211 up 0.04 RRSL_01074 o ybtP YbtP638722088 10.78735487 8.947797449 3.948 up 0.000952 RRSL_01013 o Hypothetical Protein638722089 9.276204869 8.175372449 2.366 up 0.0185 RRSL_01014 o conserved hypothetical protein638722091 10.05105487 8.937497449 2.387 up 0.018 RRSL_01016 o Hypothetical Protein638722092 10.29185487 8.431172449 4.006 up 0.0019 RRSL_01017 o Invasion protein IAGB638722093 9.465379869 8.397847449 2.312 up 0.00394 RRSL_01018 o Probable transmembrane methyl-accepting chemotaxis protein638722096 12.15740487 10.34537245 3.873 up 0.00258 RRSL_01021 o Hypothetical Protein638722097 10.09632987 7.730097449 5.688 up 0.0011 RRSL_01022 o Hypothetical Protein638722101 9.952729869 8.321322449 3.417 up 0.0181 RRSL_01027 o Gluconolactonase( EC:3.1.1.17 )638722107 11.39450487 8.270847449 9.615 up 0.00141 RRSL_01033 o 5-dehydro-4-deoxyglucarate dehydratase( EC:4.2.1.41 )638722108 11.29712987 9.276872449 4.475 up 0.00208 RRSL_01034 o Spermidine synthase( EC:2.5.1.16 )638722309 10.79042987 9.385497449 2.921 up 0.00518 RRSL_00926 o Hypothetical Protein638722330 14.24722987 9.682847449 26.101 up 0.0000814 RRSL_00947 o Hypothetical Protein638722342 12.14747987 10.76714745 2.871 up 0.0303 RRSL_00819 o Amino acid permease638722405 13.62327987 12.33362245 2.696 up 0.00182 RRSL_00783 o Hypothetical Protein638722406 13.44472987 12.02197245 2.957 up 0.0032 RRSL_00784 o Hypothetical Protein638722407 15.64172987 13.70844745 4.213 up 0.0000154 RRSL_00785 o Hypothetical Protein638722408 12.89540487 11.68709745 2.549 up 0.00376 RRSL_00786 o Hypothetical Protein638722410 12.82137987 11.47062245 2.813 up 0.0276 RRSL_00682 o Hypothetical Protein

638722432 9.668429869 8.663647449 2.213 up 0.0388 RRSL_00705 o Hypothetical Protein638722433 10.33752987 9.328022449 2.22 up 0.00949 RRSL_00706 o Hypothetical Protein638722456 10.70470487 9.409697449 2.707 up 0.00901 RRSL_00906 o Outer membrane porin protein 32 precursor638722457 9.490279869 8.404697449 2.341 up 0.0126 RRSL_00907 o Alpha-glucosidase( EC:3.2.1.20 )638722458 9.742254869 7.860622449 4.065 up 0.00785 RRSL_00908 o Hexuronate transporter638722484 10.69012987 8.978472449 3.613 up 0.000187 RRSL_01439 o Ankyrin repeat protein638722576 9.072554869 7.446897449 3.404 up 0.000877 RRSL_00571 o Hypothetical Protein638722579 13.19315487 11.59057245 3.35 up 0.0004 RRSL_00575 o Hypothetical Protein638722580 11.88927987 10.26297245 3.405 up 0.00151 RRSL_00576 o Hypothetical Protein638722582 11.10117987 9.215772449 4.075 up 0.00749 RRSL_00578 o RNA polymerase sigma-f factor for flagellar operon (fliA)638722585 10.58875487 8.511047449 4.656 up 0.0159 RRSL_00581 o Transmembrane flagellar biosynthesis protein (flhA)638722587 11.55077987 10.60732245 2.121 up 0.00592 RRSL_00583 o Transcriptional regulator, TetR family638722589 10.40120487 7.863297449 6.406 up 0.014 RRSL_00585 o 3-dehydroquinate dehydratase( EC:4.2.1.10 )638722672 9.415404869 8.100722449 2.744 up 0.0494 RRSL_00542 o Hypothetical Protein638722690 10.72672987 7.469747449 10.546 up 0.0000841 RRSL_00752 o Hypothetical Protein638722696 12.41475487 7.699372449 28.981 up 0.000601 RRSL_00759 o Nitric-oxide reductase subunit B( EC:1.7.99.7 )638722697 12.55740487 7.330597449 41.312 up 0.00157 RRSL_00760 o Hypothetical protein638722698 9.551779869 7.781072449 3.764 up 0.00509 RRSL_00634 o Hypothetical Protein638722757 13.94360487 12.87459745 2.314 up 0.0167 RRSL_00423 o Hypothetical Protein638722760 8.564429869 7.503222449 2.302 up 0.00471 RRSL_00426 o Conserved Hypothetical Protein638722778 11.08035487 10.20647245 2.021 up 0.0495 RRSL_00370 o Transcriptional regulator, ArsR family638722779 12.91975487 11.61552245 2.724 up 0.00625 RRSL_00371 o Cytochrome d ubiquinol oxidase subunit I( EC:1.10.3.- )638722943 10.86555487 9.731847449 2.42 up 0.0116 RRSL_00336 o Transporter638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638722968 11.15240487 10.18899745 2.151 up 0.00471 RRSL_00240 o Transposase638723089 9.719829869 8.473797449 2.616 up 0.00332 RRSL_00107 o Hypothetical Protein638723122 12.88257987 10.77232245 4.763 up 0.00515 RRSL_00064 o Chitinase( EC:3.2.1.14 )638718740 11.32497987 9.823597449 3.123 up 0.0117 RRSL_04591 Hypothetical Protein638718750 10.40445487 7.879347449 6.35 up 0.011 RRSL_04601 Respiratory nitrate reductase beta chain( EC:1.7.99.4 )638718751 13.23800487 9.399322449 15.783 up 0.00156 RRSL_04602 Hypothetical Protein638718754 8.704054869 7.425172449 2.676 up 0.0429 RRSL_04605 Hypothetical Protein638718769 12.97350487 11.87807245 2.357 up 0.00303 RRSL_04620 Hypothetical Protein638718793 10.75587987 9.777147449 2.174 up 0.0113 RRSL_04644 Hypothetical Protein638718794 13.32990487 12.38344745 2.126 up 0.00956 RRSL_04645 Catalase( EC:1.11.1.6 )638718808 9.696729869 7.873997449 3.902 up 0.0433 RRSL_04661 Hypothetical Protein638718809 9.946454869 8.299147449 3.455 up 0.00217 RRSL_04660 Hypothetical Protein638718868 12.35062987 10.88017245 3.057 up 0.047 RRSL_04724 Hypothetical Protein638718906 9.240304869 8.071972449 2.479 up 0.027 RRSL_04764 Hypothetical Protein638719232 9.579479869 8.666347449 2.077 up 0.00768 RRSL_04046 Hypothetical Protein638719237 12.03042987 11.00589745 2.244 up 0.0298 RRSL_04052 Hypothetical Protein638719353 12.15822987 9.609972449 6.452 up 0.00443 RRSL_04178 Hypothetical protein638719377 12.16782987 11.18614745 2.178 up 0.0147 RRSL_RNA038 ( tRNA )638719453 12.70672987 11.72249745 2.182 up 0.0048 RRSL_03828 Hypothetical Protein638719539 9.628679869 7.071247449 6.494 up 0.000805 RRSL_03920 Hypothetical Protein638719541 10.06927987 8.948422449 2.399 up 0.0071 RRSL_03922 Hypothetical Protein638719542 13.25992987 10.58272245 7.056 up 0.000358 RRSL_03923 Hypothetical Protein638719565 9.581504869 8.015247449 3.266 up 0.022 RRSL_03946 Pyridoxal-dependent aminotransferases638719566 11.25707987 8.808172449 6.023 up 0.00272 RRSL_03947 Pyridoxal-dependent aminotransferases638719571 12.02612987 8.096872449 16.806 up 0.0012 RRSL_03952 hypothetical protein638719573 10.03782987 8.412272449 3.404 up 0.0136 RRSL_03954 hypothetical protein638719746 10.98010487 9.149122449 3.924 up 0.0294 RRSL_03531 Hypothetical Protein

638719862 7.924229869 6.752497449 2.485 up 0.00158 RRSL_03560 Hypothetical Protein638719887 10.43677987 8.379997449 4.589 up 0.0269 RRSL_03586 Hypothetical Protein638720190 8.435954869 7.574497449 2.004 up 0.00634 RRSL_03712 Hypothetical Protein638720250 11.36557987 9.907122449 3.031 up 0.00686 RRSL_03415 Hypothetical Protein638720333 14.56972987 13.69874745 2.017 up 0.0194 RRSL_03080 Hypothetical Protein638720383 10.35167987 9.174672449 2.494 up 0.00963 RRSL_02964 Hypothetical Protein638720384 9.738629869 8.435422449 2.722 up 0.00869 RRSL_02965 Hypothetical Protein638720385 11.61875487 10.22169745 2.905 up 0.00186 RRSL_02966 Phospholipase C( EC:3.1.4.3 )638720478 15.09760487 14.00942245 2.345 up 0.00293 RRSL_03244 Hypothetical Protein638720548 10.36037987 8.160697449 5.067 up 0.0007 RRSL_02858 hypothetical protein638720549 9.565879869 7.252972449 5.481 up 0.00175 RRSL_02859 Acyl-CoA dehydrogenase, short-chain specific( EC:1.3.99.2 )638720550 12.25197987 9.689072449 6.518 up 0.00000598 RRSL_02860 hypothetical protein638720551 9.993404869 8.235797449 3.73 up 0.00325 RRSL_02861 hypothetical protein638720552 10.43372987 8.283822449 4.895 up 0.000258 RRSL_02862 hypothetical protein638720553 11.36065487 9.085747449 5.339 up 0.000965 RRSL_02863 Polyketide synthase638720554 11.48080487 9.836547449 3.448 up 0.000619 RRSL_02864 Thioesterase( EC:3.1.2.- )638720609 10.56167987 9.121272449 2.994 up 0.00454 RRSL_02925 hypothetical protein638720614 11.88337987 9.423097449 6.071 up 0.0146 RRSL_02789 aidA AidA638720615 10.13620487 8.961122449 2.491 up 0.0172 RRSL_02790 Hypothetical protein638720662 8.685129869 7.475222449 2.551 up 0.00254 RRSL_02842 livH LivH638720756 13.89525487 11.77204745 4.806 up 0.00432 RRSL_02046 Hypothetical Protein638720757 16.03335487 12.77229745 10.576 up 0.00179 RRSL_02047 Hypothetical Protein638720758 9.456829869 8.091597449 2.842 up 0.0325 RRSL_02048 Hypothetical Protein638720767 15.13760487 13.41769745 3.634 up 0.000652 RRSL_02057 Uncharacterized protein conserved in bacteria638720768 13.38502987 11.62424745 3.738 up 0.000626 RRSL_02058 Hypothetical Protein638720772 13.51955487 12.08752245 2.976 up 0.0262 RRSL_02063 Hypothetical Protein638720813 8.986154869 7.102997449 4.069 up 0.0183 RRSL_02294 Hypothetical Protein638720873 10.49782987 9.219272449 2.676 up 0.0445 RRSL_02356 Hypothetical Protein638721172 11.67085487 10.16077245 3.142 up 0.00261 RRSL_02152 Hypothetical protein638721179 13.36932987 10.82652245 6.428 up 0.000672 RRSL_02159 Hypothetical protein638721186 11.50217987 10.01162245 3.099 up 0.00336 RRSL_02166 Hypothetical protein638721585 12.72900487 9.885872449 7.916 up 0.000397 RRSL_01783 Hypothetical Protein638721608 9.345504869 8.466822449 2.028 up 0.0158 RRSL_01808 Hypothetical Protein638721730 13.46417987 12.17462245 2.696 up 0.00551 RRSL_01669 Hypothetical Protein638721764 10.06427987 8.263872449 3.842 up 0.03 RRSL_01563 Atypical orf638721965 11.82535487 10.74814745 2.327 up 0.00283 RRSL_01114 Hypothetical Protein638722044 11.58255487 9.858772449 3.643 up 0.00415 RRSL_01069 hypothetical protein638722045 14.35917987 11.97682245 5.751 up 0.000409 RRSL_01070 Hypothetical Protein638722055 9.758504869 8.652547449 2.374 up 0.0292 RRSL_01251 Hypothetical Protein638722094 13.44032987 9.574422449 16.084 up 0.00003 RRSL_01019 Hypothetical Protein638722095 13.05900487 8.797347449 21.161 up 0.0000995 RRSL_01020 Atypical ORF638722119 11.26687987 9.167847449 4.726 up 0.000845 RRSL_01204 Hypothetical Protein638722120 9.743054869 8.821372449 2.089 up 0.0112 RRSL_01205 Site-specific recombinases638722122 11.83302987 10.96914745 2.007 up 0.00468 RRSL_01207 Predicted transcriptional regulators638722265 9.994204869 8.814747449 2.498 up 0.0171 RRSL_01480 Multidrug resistance protein B638722314 10.07917987 8.727122449 2.816 up 0.0254 RRSL_00931 Hypothetical Protein638722361 11.61980487 9.881872449 3.679 up 0.0124 RRSL_00837 Transcriptional regulator638722404 9.901779869 8.304072449 3.338 up 0.000599 RRSL_00782 Hypothetical protein638722409 12.01437987 10.24114745 3.77 up 0.0176 RRSL_00681 Hypothetical protein638722423 12.02735487 9.288597449 7.363 up 0.00158 RRSL_00696 Hypothetical Protein638722438 10.51517987 9.420997449 2.355 up 0.0411 RRSL_00714 Catechol 1,2-dioxygenase( EC:1.13.11.1 )638722511 13.01600487 11.75544745 2.643 up 0.0469 RRSL_00997 Hypothetical protein638722625 9.737979869 8.164172449 3.284 up 0.0017 RRSL_00472 Hypothetical protein638722638 10.84790487 9.455897449 2.895 up 0.0111 RRSL_00485 Hypothetical Protein638722667 10.18972987 8.837197449 2.817 up 0.00359 RRSL_00537 Glutathione S-transferase( EC:2.5.1.18 )638722695 9.782379869 7.179747449 6.7 up 0.00552 RRSL_00758 Hypothetical protein638722741 11.18610487 9.510797449 3.523 up 0.00906 RRSL_00600 hypothetical protein

638722772 8.658954869 7.496072449 2.47 up 0.0322 RRSL_00439Benzoate 1,2-dioxygenase alpha subunit / Toluate 1,2-dioxygenase alpha subunit( EC:1.14.12.-,EC:1.14.12.10 )

638722883 9.138379869 7.341772449 3.832 up 0.00928 RRSL_00271 Hypothetical Protein638722884 9.933229869 8.450122449 3.083 up 0.0000887 RRSL_00272 Succinate-semialdehyde dehydrogenase (NADP+)( EC:1.2.1.16 )638722885 9.647679869 8.608547449 2.267 up 0.0292 RRSL_00273 Tartrate dehydrogenase( EC:1.1.1.93 )638722886 9.238254869 8.068072449 2.482 up 0.00661 RRSL_00274 Transporter638722887 11.83807987 9.280222449 6.495 up 0.00271 RRSL_00275 dppC DppC638722888 10.43370487 8.607447449 3.912 up 0.00651 RRSL_00276 dppB DppB638722889 9.921279869 8.013472449 4.139 up 0.00152 RRSL_00277 Dipeptide-binding protein638722890 8.993304869 7.886272449 2.376 up 0.00178 RRSL_00278 Oxidoreductase( EC:1.- )638722891 10.68522987 8.590872449 4.711 up 0.0026 RRSL_00279 Probable 2-haloacid halidohydrolase IVa638722892 9.902204869 7.698072449 5.083 up 0.0342 RRSL_00281 Aldehyde dehydrogenase( EC:1.2.1.3 )638722893 9.683104869 8.108122449 3.286 up 0.0327 RRSL_00282 Aldehyde dehydrogenase( EC:1.2.1.3 )638722896 10.80232987 9.287247449 3.153 up 0.00208 RRSL_00286 Probable aminotransferase Y4UB( EC:2.6.1.- )638722899 8.534254869 7.657222449 2.026 up 0.0265 RRSL_00290 Possible Glycine/D-amino acid oxidase (deaminating).638722949 10.42832987 8.836247449 3.325 up 0.0276 RRSL_00220 Hypothetical protein638722966 9.736104869 8.790597449 2.124 up 0.0294 RRSL_00237 Shikimate kinase( EC:2.7.1.71 )638723005 15.19222987 13.93169745 2.643 up 0.000229 RRSL_00169 Hypothetical Protein638723017 9.232129869 7.809822449 2.956 up 0.0114 RRSL_00256 Hypothetical Protein638723036 8.829104869 7.663022449 2.475 up 0.0468 RRSL_00198 probable sodium/solute symporter638723039 12.37265487 11.18464745 2.513 up 0.0419 RRSL_00201 Phage protein638723121 9.914454869 8.295697449 3.388 up 0.0483 RRSL_00063 Hypothetical Protein638723153 14.99622987 13.86374745 2.418 up 0.000353 RRSL_00009 Hypothetical Protein638718914 10.80987987 12.29484745 2.537 down 0.0266 RRSL_04773 o c Phosphogluconate dehydratase( EC:4.2.1.12 )638718915 10.67502987 12.93297245 4.335 down 0.00918 RRSL_04774 o c Glucose-6-phosphate 1-dehydrogenase( EC:1.1.1.49 )638718916 8.585129869 10.67559745 3.86 down 0.00896 RRSL_04775 o c 6-phosphogluconolactonase( EC:3.1.1.31 )638718917 8.546904869 10.20624745 2.863 down 0.00635 RRSL_04776 o c Glucokinase( EC:2.7.1.2 )638718940 12.41350487 13.79474745 2.361 down 0.0127 RRSL_04395 o c Aromatic-amino-acid aminotransferase( EC:2.6.1.1,EC:2.6.1.57 )638718941 11.25872987 12.43367245 2.046 down 0.0113 RRSL_04396 o c phaZ PhaZ638718944 11.13922987 12.36872245 2.125 down 0.00155 RRSL_04399 o c Oxygen-insensitive NAD(P)H nitroreductase( EC:1.- )638718956 11.55540487 12.82319745 2.182 down 0.00168 RRSL_04412 o c hypothetical cytosolic protein638718957 10.77740487 12.87929745 3.891 down 0.00129 RRSL_04413 o c htpG HtpG638718970 11.14327987 12.31049745 2.035 down 0.0222 RRSL_04426 o c Topoisomerase IV subunit B638718992 9.068804869 10.52529745 2.487 down 0.00793 RRSL_04450 o c hypothetical cytosolic protein638718993 11.23717987 12.82187245 2.718 down 0.00303 RRSL_04451 o c hypothetical protein638719000 9.457379869 10.91162245 2.483 down 0.0211 RRSL_04458 o c Molybdopterin biosynthesis mog protein638719009 11.52100487 12.75419745 2.13 down 0.0488 RRSL_04467 o c rimM RimM638719016 9.944329869 12.94717245 7.265 down 0.0019 RRSL_04475 o c D-amino acid dehydrogenase small subunit( EC:1.4.99.1 )638719017 8.962454869 10.20159745 2.139 down 0.00189 RRSL_04476 o c Acyl-CoA dehydrogenase( EC:1.3.99.3 )638719018 11.43057987 12.71942245 2.214 down 0.0055 RRSL_04477 o c Electron transfer flavoprotein beta-subunit638719060 11.06735487 12.53452245 2.506 down 0.0139 RRSL_04521 o c Oligopeptidase A( EC:3.4.24.70 )

638719061 10.70285487 12.13522245 2.446 down 0.0112 RRSL_04522 o cMethylenetetrahydrofolate dehydrogenase (NADP+) / Methenyltetrahydrofolate cyclohydrolase( EC:1.5.1.5,EC:3.5.4.9 )

638719064 13.77405487 15.15827245 2.366 down 0.00552 RRSL_04525 o c Pyruvate dehydrogenase E1 component( EC:1.2.4.1 )638719065 10.98147987 13.01949745 3.722 down 0.00971 RRSL_04526 o c Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex( EC:2.3.1.12 )638719066 12.53235487 14.22217245 2.924 down 0.00243 RRSL_04527 o c hypothetical protein638719067 10.50430487 12.51254745 3.646 down 0.014 RRSL_04528 o c Dihydrolipoamide dehydrogenase( EC:1.8.1.4 )638719088 9.751804869 11.90002245 4.018 down 0.000942 RRSL_04550 o c TRANSCRIPTION ACCESSORY PROTEIN (S1 RNA binding domain)638719094 11.07132987 12.79207245 2.987 down 0.0209 RRSL_04555 o c Poly(3-hydroxyalkanoate) polymerase( EC:2.3.1.- )638719095 12.41437987 14.07897245 2.873 down 0.0146 RRSL_04556 o c phbA PhbA( EC:2.3.1.9 )638719096 12.96895487 14.26379745 2.223 down 0.0123 RRSL_04557 o c Acetoacetyl-CoA reductase( EC:1.1.1.36 )638719097 12.69745487 13.90322245 2.09 down 0.00965 RRSL_04558 o c Conserved hypothetical protein638719104 9.691004869 10.98914745 2.229 down 0.0146 RRSL_04565 o c Phosphoserine phosphatase( EC:3.1.3.3 )638719116 9.196179869 10.35027245 2.017 down 0.00148 RRSL_04579 o c transmembrane protein transport/efflux protein638719123 13.10012987 14.41399745 2.253 down 0.0146 RRSL_04585 o c ATP-dependent Clp protease proteolytic subunit( EC:3.4.21.92 )638719129 11.64990487 12.90607245 2.165 down 0.0119 RRSL_04589 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638719145 11.52562987 13.31454745 3.132 down 0.0121 RRSL_04295 o c Glucosamine--fructose-6-phosphate aminotransferase (isomerizing)( EC:2.6.1.16 )

638719147 9.564654869 10.88214745 2.259 down 0.00508 RRSL_04297 o c tRNA s2C32 biosynthesis protein TtcA638719176 11.06800487 12.48204745 2.415 down 0.0057 RRSL_04327 o c N-acetyl-gamma-glutamyl-phosphate reductase( EC:1.2.1.38 )638719197 11.72060487 13.18572245 2.502 down 0.000284 RRSL_04350 o c Amino-acid ABC transporter binding protein ybeJ precursor638719206 11.20870487 13.16514745 3.517 down 0.0016 RRSL_04359 o c thiC ThiC638719207 9.161379869 10.54442245 2.364 down 0.00254 RRSL_04360 o c Glycine oxidase( EC:1.4.3.19 )638719208 8.035104869 9.420422449 2.367 down 0.00134 RRSL_04362 o c thiG ThiG638719221 10.74835487 11.96579745 2.107 down 0.00191 RRSL_04376 o c Soluble lytic murein transglycosylase( EC:3.2.1.- )638719224 10.52650487 11.77162245 2.148 down 0.0075 RRSL_04380 o c conserved hypothetical protein638719225 8.777979869 10.06664745 2.214 down 0.00585 RRSL_04381 o c tRNA nucleotidyltransferase( EC:2.7.7.25 )638719250 11.46272987 12.83449745 2.345 down 0.00553 RRSL_04068 o c Glutathione-dependent formaldehyde dehydrogenase( EC:1.2.1.1 )638719251 9.032054869 10.52737245 2.555 down 0.0223 RRSL_04069 o c S-formylglutathione hydrolase( EC:3.1.1.1,EC:3.1.2.12 )638719258 10.25465487 11.80089745 2.647 down 0.00432 RRSL_04077 o c Hypothetical Protein638719285 11.55427987 13.45492245 3.384 down 0.00541 RRSL_04104 o c Fructose-bisphosphate aldolase( EC:4.1.2.13 )638719286 10.88097987 12.37274745 2.549 down 0.0108 RRSL_04105 o c Hypothetical Protein( EC:2.7.1.40 )638719287 10.48917987 12.36717245 3.331 down 0.0097 RRSL_04106 o c Phosphoglycerate kinase( EC:2.7.2.3 )638719291 11.12480487 12.59727245 2.515 down 0.00317 RRSL_04110 o c Branched-chain amino acid aminotransferase( EC:2.6.1.42 )638719293 10.26355487 11.66469745 2.394 down 0.0172 RRSL_04112 o c ADP-heptose--LPS heptosyltransferase II( EC:2.- )638719325 9.458954869 10.73462245 2.194 down 0.0102 RRSL_04148 o c NADPH-dependent glutamate synthase beta chain and related oxidoreductases638719326 11.47210487 12.72172245 2.155 down 0.00405 RRSL_04149 o c probable signal peptide638719335 10.79925487 12.14612245 2.305 down 0.0157 RRSL_04159 o c Glycyl-tRNA synthetase beta chain( EC:6.1.1.14 )638719359 9.971704869 11.46209745 2.546 down 0.00825 RRSL_04185 o c Hypothetical Protein638719360 11.75390487 13.44674745 2.93 down 0.000554 RRSL_04186 o c Putative integral membrane protein638719379 9.102954869 10.34854745 2.149 down 0.0034 RRSL_04205 o c Queuosine biosynthesis protein QueC638719381 13.67807987 14.98699745 2.245 down 0.027 RRSL_04207 o c Peptidoglycan-associated lipoprotein638719382 11.98305487 13.37844745 2.384 down 0.00138 RRSL_04208 o c TolB protein638719383 10.26582987 11.78469745 2.597 down 0.017 RRSL_04209 o c TolA protein638719384 10.86440487 12.15009745 2.209 down 0.0323 RRSL_04210 o c TolR protein638719387 13.20125487 14.51492245 2.253 down 0.0115 RRSL_04213 o c Serine hydroxymethyltransferase( EC:2.1.2.1 )638719402 9.778704869 11.32189745 2.641 down 0.0119 RRSL_04229 o c GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone-4-phosphate synthase( EC:3.5.4.25,EC:4.1.2.- )638719404 12.17932987 13.39362245 2.103 down 0.0116 RRSL_04231 o c N utilization substance protein B638719414 9.316654869 10.50837245 2.07 down 0.00123 RRSL_04240 o c tRNA (m(7)G46) methyltransferase( EC:2.1.1.33 )638719420 11.58545487 12.95509745 2.342 down 0.0088 RRSL_04246 o c Protein-L-isoaspartate O-methyltransferase( EC:2.1.1.77 )638719421 8.499854869 10.53324745 3.71 down 0.00218 RRSL_04247 o c Hypothetical Protein638719422 10.16030487 11.40429745 2.146 down 0.000942 RRSL_04248 o c Type I secretion outer membrane protein638719423 9.587779869 11.22877245 2.827 down 0.000379 RRSL_04249 o c Hypothetical Protein638719450 10.43702987 11.99447245 2.667 down 0.0148 RRSL_03825 o c Acetyl-coenzyme A synthetase( EC:6.2.1.1 )638719457 9.062829869 10.45884745 2.385 down 0.00649 RRSL_03832 o c Endonuclease( EC:3.1.- )638719458 10.11037987 11.55672245 2.47 down 0.0175 RRSL_03833 o c 16S rRNA m(5)C 967 methyltransferase( EC:2.1.1.- )638719459 11.03602987 12.50054745 2.501 down 0.00986 RRSL_03834 o c Phosphoribosylglycinamide formyltransferase( EC:2.1.2.2 )638719462 9.414829869 10.85479745 2.459 down 0.0127 RRSL_03837 o c Riboflavin kinase / FMN adenylyltransferase( EC:2.7.1.26,EC:2.7.7.2 )638719463 10.50642987 12.07412245 2.687 down 0.0127 RRSL_03838 o c Isoleucyl-tRNA synthetase( EC:6.1.1.5 )638719470 10.99070487 13.14732245 4.041 down 0.00431 RRSL_03846 o c Cold shock protein638719498 10.86927987 12.30354745 2.449 down 0.0157 RRSL_03878 o c Phosphatidylserine decarboxylase( EC:4.1.1.65 )638719499 10.31550487 11.48422245 2.037 down 0.0276 RRSL_03879 o c CDP-diacylglycerol--serine O-phosphatidyltransferase( EC:2.7.8.8 )638719500 11.10107987 12.40264745 2.234 down 0.0476 RRSL_03880 o c 2-isopropylmalate synthase( EC:4.1.3.12 )638719507 9.802829869 11.91797245 3.927 down 0.00816 RRSL_03888 o c Triosephosphate isomerase( EC:5.3.1.1 )638719508 9.890604869 11.75129745 3.292 down 0.0232 RRSL_03889 o c Protein translocase subunit secG638719512 11.56640487 12.92544745 2.325 down 0.0275 RRSL_03892 o c NADH-quinone oxidoreductase chain C( EC:1.6.5.3,EC:1.6.99.5 )638719516 9.178704869 11.14962245 3.553 down 0.0236 RRSL_03896 o c NADH-quinone oxidoreductase chain G( EC:1.6.5.3 )638719521 12.48050487 13.66024745 2.053 down 0.0278 RRSL_03901 o c NADH-quinone oxidoreductase chain L( EC:1.6.5.3 )638719523 11.40737987 12.70909745 2.234 down 0.0283 RRSL_03903 o c NADH-quinone oxidoreductase chain N( EC:1.6.5.3 )638719606 8.458179869 9.802297449 2.301 down 0.0166 RRSL_03988 o c gspF GspF638719608 8.923804869 10.33342245 2.408 down 0.0184 RRSL_03990 o c gspE GspE638719612 8.762854869 9.913647449 2.012 down 0.0259 RRSL_03994 o c gspL GspL638719615 8.728054869 10.18407245 2.486 down 0.0129 RRSL_03997 o c gspI GspI638719620 10.44320487 13.25349745 6.358 down 0.0012 RRSL_04002 o c 4-hydroxyphenylpyruvate dioxygenase( EC:1.13.11.27 )638719628 7.899004869 9.459597449 2.673 down 0.00593 RRSL_04011 o c hypothetical protein

638719662 10.27335487 11.52714745 2.161 down 0.0172 RRSL_03445 o c yicC YicC638719665 9.303479869 10.81577245 2.585 down 0.00979 RRSL_03447 o c Ribonuclease PH( EC:2.7.7.56 )638719672 10.44807987 11.92522245 2.523 down 0.012 RRSL_03453 o c Permease638719673 9.040579869 10.47969745 2.457 down 0.00026 RRSL_03454 o c Permease638719675 7.506679869 8.740922449 2.132 down 0.00469 RRSL_03456 o c Regulator of kinase autophosphorylation inhibitor638719676 8.316204869 9.595147449 2.199 down 0.0122 RRSL_03457 o c kipI KipI638719710 11.62122987 14.23819745 5.56 down 0.00039 RRSL_03494 o c Trp repressor binding protein638719711 9.582054869 13.00774745 9.74 down 0.000203 RRSL_03495 o c Pirin638719712 8.869779869 10.06909745 2.081 down 0.00864 RRSL_03496 o c Transcriptional regulators, LysR family638719722 10.50415487 11.77667245 2.189 down 0.0231 RRSL_03505 o c GatB/Yqey domain protein638719729 9.030954869 10.50902245 2.525 down 0.0178 RRSL_03512 o c Exodeoxyribonuclease VII small subunit( EC:3.1.11.6 )638719808 10.63930487 12.21289745 2.698 down 0.0183 RRSL_03771 o c Hypothetical membrane spanning protein638719814 8.685254869 9.895547449 2.097 down 0.000933 RRSL_03777 o c hypothetical protein638719819 10.99962987 12.42702245 2.438 down 0.00482 RRSL_03782 o c hypothetical protein638719825 10.64107987 12.03389745 2.38 down 0.00688 RRSL_03790 o c Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase( EC:5.3.1.16 )638719827 12.29352987 14.57179745 4.397 down 0.0093 RRSL_03792 o c hypothetical protein638719832 10.25082987 11.49329745 2.144 down 0.0339 RRSL_03797 o c hypothetical protein638719834 12.36567987 13.52669745 2.026 down 0.00793 RRSL_03799 o c Aspartyl-tRNA synthetase( EC:6.1.1.12 )

638719841 11.09345487 12.58892245 2.555 down 0.0386 RRSL_03806 o cenoyl-coa hydratase / 3,2-trans-enoyl-coa isomerase / 3-hydroxyacyl-coa dehydrogenase( EC:1.1.1.35,EC:4.2.1.17,EC:5.3.3.8 )

638719846 12.45117987 14.72697245 4.389 down 0.00887 RRSL_03812 o c gdhA GdhA( EC:1.4.1.3 )638719847 15.02422987 16.17269745 2.009 down 0.0024 RRSL_03813 o c Glutamate/aspartate-binding protein638719848 10.89555487 12.63847245 3.034 down 0.00611 RRSL_03814 o c gltJ GltJ638719849 11.56102987 13.16064745 2.747 down 0.00103 RRSL_03815 o c gltK GltK638719850 11.78282987 13.15479745 2.346 down 0.0022 RRSL_03816 o c gltL GltL638719876 13.97685487 15.16014745 2.058 down 0.0166 RRSL_03575 o c livH LivH638719877 13.21027987 14.55934745 2.309 down 0.00585 RRSL_03576 o c livM LivM638719878 11.87527987 13.39312245 2.595 down 0.0131 RRSL_03577 o c livG LivG638719879 10.94755487 12.22954745 2.204 down 0.0483 RRSL_03578 o c livF LivF638719903 11.45667987 12.71904745 2.174 down 0.00422 RRSL_03601 o c Cytosol aminopeptidase( EC:3.4.11.1 )638719940 12.54402987 14.18754745 2.832 down 0.0146 RRSL_03640 o c Superoxide dismutase (Cu-Zn)( EC:1.15.1.1 )638719941 10.47512987 11.64884745 2.044 down 0.00125 RRSL_03641 o c NAD-dependent formate dehydrogenase delta subunit (fdsD)( EC:1.2.1.2 )638719944 10.31447987 11.54139745 2.121 down 0.0147 RRSL_03645 o c Argininosuccinate lyase( EC:4.3.2.1 )638719950 11.74335487 13.34784745 2.756 down 0.00942 RRSL_00716 o c Protein translocase subunit secD638719952 13.57817987 15.85002245 4.377 down 0.00104 RRSL_00718 o c Hypothetical exported protein638719953 11.88950487 14.41149745 5.206 down 0.00248 RRSL_00719 o c Hypothetical Protein638719954 8.490379869 11.81114745 9.057 down 0.000246 RRSL_00720 o c Cytochrome b561638719958 8.895279869 10.60254745 2.959 down 0.00218 RRSL_00725 o c Phosphohydrolase (MutT/nudix family protein)638719963 9.044804869 10.47554745 2.443 down 0.00632 RRSL_00729 o c Ferrichrome-iron receptor638719974 10.18542987 11.49134745 2.241 down 0.0133 RRSL_02706 o c Gamma-glutamyl phosphate reductase( EC:1.2.1.41 )638719975 9.276979869 10.48027245 2.087 down 0.0195 RRSL_02705 o c DNA polymerase III, delta subunit( EC:2.7.7.7 )638719978 10.88725487 12.13017245 2.145 down 0.0192 RRSL_02702 o c dapB DapB( EC:1.3.1.26 )638719983 12.79297987 13.96897245 2.048 down 0.0164 RRSL_02697 o c Glyceraldehyde 3-phosphate dehydrogenase( EC:1.2.1.12 )638719984 11.96457987 13.30432245 2.294 down 0.0107 RRSL_02696 o c Transketolase( EC:2.2.1.1 )638719990 11.22822987 12.92452245 2.937 down 0.00729 RRSL_02689 o c NADP-dependent malic enzyme( EC:1.1.1.40 )638719998 9.640204869 10.79857245 2.023 down 0.00902 RRSL_02680 o c Shikimate 5-dehydrogenase( EC:1.1.1.25 )638720007 11.51335487 13.14664745 2.812 down 0.0192 RRSL_02671 o c Biotin carboxyl carrier protein of acetyl-CoA carboxylase( EC:6.4.1.2 )638720008 10.57707987 12.27594745 2.942 down 0.0111 RRSL_02670 o c Biotin carboxylase( EC:6.3.4.14,EC:6.4.1.2 )638720009 10.76100487 12.08167245 2.264 down 0.0156 RRSL_02669 o c Ribosomal protein L11 methyltransferase( EC:2.1.1.- )638720011 12.95217987 14.60847245 2.857 down 0.00292 RRSL_02667 o c Thioredoxin peroxidase638720012 12.52455487 13.88877245 2.333 down 0.000689 RRSL_02666 o c Adenosine kinase( EC:2.7.1.20 )638720013 11.33710487 13.18812245 3.27 down 0.011 RRSL_02665 o c Outer membrane lipoprotein638720021 10.08040487 11.28509745 2.089 down 0.00645 RRSL_02654 o c Hypothetical Protein638720033 11.62102987 12.81334745 2.071 down 0.00157 RRSL_02639 o c Prolyl-tRNA synthetase( EC:6.1.1.15 )638720046 11.86347987 13.19292245 2.277 down 0.000622 RRSL_03274 o c Zinc protease( EC:3.4.99.- )638720047 10.92125487 12.96612245 3.74 down 0.000124 RRSL_03275 o c Zinc protease( EC:3.4.99.- )638720048 10.02490487 11.35292245 2.275 down 0.00516 RRSL_03276 o c ftsY FtsY

638720049 11.14225487 12.56167245 2.424 down 0.00015 RRSL_03278 o c Hypothetical Protein( EC:5.2.1.2 )638720058 12.07950487 13.23667245 2.021 down 0.00877 RRSL_03287 o c RNA polymerase sigma-32 factor638720069 11.74975487 13.09457245 2.302 down 0.0356 RRSL_03298 o c Cytochrome c oxidase polypeptide I( EC:1.9.3.1 )638720070 13.44272987 14.60394745 2.027 down 0.0034 RRSL_03299 o c Cytochrome c oxidase polypeptide II( EC:1.9.3.1 )638720086 10.18137987 11.44022245 2.169 down 0.0233 RRSL_03315 o c PTS system, IIA component( EC:2.7.1.69 )638720125 10.71312987 12.24572245 2.622 down 0.0475 RRSL_03354 o c Seryl-tRNA synthetase( EC:6.1.1.11 )638720132 12.94605487 15.36424745 4.845 down 0.000257 RRSL_03652 o c Glycine cleavage system H protein638720133 10.64670487 14.10169745 9.94 down 0.000105 RRSL_03653 o c gcvP GcvP( EC:1.4.4.2 )638720141 13.11302987 14.99959745 3.351 down 0.00088 RRSL_03661 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638720142 9.470779869 11.63819745 4.071 down 0.0013 RRSL_03662 o c Proline dehydrogenase / Delta-1-pyrroline-5-carboxylate dehydrogenase( EC:1.5.1.12,EC:1.5.99.8 )638720144 9.959304869 11.25322245 2.222 down 0.00156 RRSL_03665 o c Uroporphyrinogen decarboxylase( EC:4.1.1.37 )638720158 11.65522987 13.18697245 2.62 down 0.02 RRSL_03679 o c ATP synthase epsilon chain( EC:3.6.3.14 )638720159 13.49265487 14.69844745 2.09 down 0.0177 RRSL_03680 o c ATP synthase beta chain( EC:3.6.3.14 )638720161 13.18565487 14.93897245 3.055 down 0.00906 RRSL_03682 o c ATP synthase alpha chain( EC:3.6.3.14 )638720171 10.85382987 12.31484745 2.495 down 0.000208 RRSL_03692 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638720295 11.18285487 14.51259745 9.113 down 0.0000781 RRSL_03040 o c Porin638720296 11.79480487 15.09677245 8.94 down 0.000593 RRSL_03041 o c D-xylose-binding protein638720297 9.986579869 13.51424745 10.453 down 0.000177 RRSL_03042 o c xylG XylG638720298 10.81895487 13.76069745 6.964 down 0.0000134 RRSL_03043 o c xylH XylH638720341 12.55885487 14.17849745 2.785 down 0.006 RRSL_03090 o c rpoN RpoN638720360 11.69257987 13.31729745 2.795 down 0.00164 RRSL_02940 o c Drug efflux lipoprotein (FUSA/NODT family)638720361 11.16437987 12.85504745 2.926 down 0.00263 RRSL_02941 o c Acriflavin resistance protein (acrB)638720362 9.077179869 11.30019745 4.231 down 0.00351 RRSL_02942 o c Probable acriflavin resistance lipoprotein A precursor638720366 9.208804869 11.83614745 5.6 down 0.00167 RRSL_02946 o c conserved hypothetical protein638720392 10.58477987 11.92314745 2.292 down 0.00976 RRSL_02973 o c Hypothetical exported protein638720394 8.103429869 9.625897449 2.604 down 0.021 RRSL_02975 o c prrA PrrA638720409 9.222404869 10.46769745 2.148 down 0.0158 RRSL_02991 o c Precorrin-3B C17-methyltransferase / Precorrin-6X reductase( EC:1.3.1.54,EC:2.1.1.131 )638720419 10.69907987 11.88552245 2.063 down 0.0106 RRSL_03001 o c hupN HupN638720427 12.81702987 14.69199745 3.324 down 0.000651 RRSL_03189 o c dnaK DnaK638720430 11.15247987 13.07364745 3.433 down 0.00172 RRSL_03192 o c probable heat shock protein 24 (HSP-70 cofactor)638720442 10.62650487 11.80114745 2.046 down 0.0146 RRSL_03205 o c Hypothetical Protein638720457 11.45485487 12.92854745 2.517 down 0.00125 RRSL_03222 o c Murein hydrolase exporter638720458 9.791479869 10.96084745 2.038 down 0.00254 RRSL_03223 o c Murein hydrolase export regulator638720577 10.04200487 11.42237245 2.359 down 0.000935 RRSL_02891 o c hypothetical protein638720595 10.46450487 13.06979745 5.515 down 0.00149 RRSL_02910 o c transmembrane protein638720597 9.322204869 11.58599745 4.353 down 0.0153 RRSL_02912 o c Sensor protein rstB( EC:2.7.3.- )638720608 9.494529869 11.33357245 3.243 down 0.000228 RRSL_02924 o c Glycerol kinase( EC:2.7.1.30 )638720674 8.830654869 10.59822245 3.086 down 0.0108 RRSL_02853 o c Fumarate hydratase class II( EC:4.2.1.2 )638720680 10.46447987 12.45379745 3.599 down 0.0000796 RRSL_02713 o c Coenzyme F390 Synthetase / Phenylacetate-coenzyme A ligase( EC:6.2.1.30 )638720685 9.835979869 11.49519745 2.862 down 0.00292 RRSL_02718 o c Hypothetical Protein( EC:4.1.3.27 )638720687 7.598629869 9.203322449 2.756 down 0.00328 RRSL_02720 o c Hypothetical Protein638720689 10.48422987 11.69712245 2.101 down 0.00296 RRSL_02722 o c Indole-3-glycerol phosphate synthase( EC:4.1.1.48 )638720690 9.063129869 10.75694745 2.932 down 0.000582 RRSL_02723 o c Putative adenylate cyclase family638720701 12.15435487 13.37897245 2.118 down 0.00241 RRSL_02734 o c GTP-binding protein, probable translation factor638720709 10.68322987 12.15502245 2.514 down 0.00316 RRSL_02742 o c Hypothetical Protein638720715 11.71270487 13.00332245 2.217 down 0.0139 RRSL_02748 o c Hypothetical Protein638720721 9.354504869 10.55204745 2.078 down 0.00147 RRSL_02754 o c FecR protein638720728 9.913779869 12.01389745 3.886 down 0.00825 RRSL_02760 o c Stringent starvation protein A638720734 11.54502987 12.69964745 2.017 down 0.0072 RRSL_02766 o c Protease Do( EC:3.4.21.- )638720743 10.66905487 11.92579745 2.166 down 0.0172 RRSL_02775 o c tatB TatB638720746 11.37565487 12.73857245 2.331 down 0.00181 RRSL_02778 o c Phosphoribosyl-ATP pyrophosphatase( EC:3.6.1.31 )638720761 14.33612987 15.77049745 2.449 down 0.00518 RRSL_02051 o c 60 kDa chaperonin GROEL638720882 10.59175487 12.08694745 2.555 down 0.00479 RRSL_02369 o c Glutaminyl-tRNA synthetase( EC:6.1.1.18 )638720887 10.45112987 11.94579745 2.554 down 0.0262 RRSL_02374 o c Alanyl-tRNA synthetase( EC:6.1.1.7 )638720891 10.58872987 12.41117245 3.205 down 0.000685 RRSL_02379 o c purine nucleoside permease638720892 9.331879869 11.41597245 3.843 down 0.00036 RRSL_02380 o c purine nucleoside permease638720955 8.647204869 10.32539745 2.9 down 0.00719 RRSL_02173 o c Polyphosphate kinase( EC:2.7.4.1 )

638720967 11.19140487 12.41524745 2.117 down 0.0329 RRSL_02184 o c Hypothetical RNA binding protein638720968 10.90265487 12.45424745 2.657 down 0.0133 RRSL_02186 o c Hypothetical Protein638720969 10.49567987 12.19504745 2.943 down 0.0269 RRSL_02187 o c Transcription elongation factor greA (transcription cleavage factor)638720970 11.40777987 12.78567245 2.355 down 0.0386 RRSL_02188 o c Carbamoyl-phosphate synthase large chain( EC:6.3.5.5 )638720971 12.08207987 13.48042245 2.389 down 0.00343 RRSL_02189 o c Transporter, LysE family638721129 9.274654869 10.91364745 2.823 down 0.00111 RRSL_02108 o c Transcriptional regulators, LysR family638721130 10.49742987 11.73987245 2.144 down 0.000259 RRSL_02109 o c glutarate--CoA ligase( EC:6.2.1.6 )638721131 12.81510487 14.39019745 2.7 down 0.00156 RRSL_02110 o c ABC transporter substrate-binding protein638721132 9.974079869 11.50872245 2.626 down 0.00133 RRSL_02111 o c ABC transporter ATP-binding protein638721133 11.24732987 12.59027245 2.299 down 0.00284 RRSL_02113 o c ABC transporter permease protein638721142 12.86435487 14.16769745 2.237 down 0.0101 RRSL_02122 o c SecY stabilizing membrane protein638721154 9.746579869 11.29479745 2.65 down 0.0233 RRSL_02134 o c Protease activity modulator HflK638721157 8.542954869 9.916597449 2.348 down 0.00272 RRSL_02137 o c Histidyl-tRNA synthetase( EC:6.1.1.21 )638721165 10.77895487 11.92639745 2.007 down 0.000258 RRSL_02144 o c Ribose 5-phosphate isomerase( EC:5.3.1.6 )638721241 10.95712987 12.61274745 2.855 down 0.0283 RRSL_02572 o c 3-hydroxybutyryl-CoA dehydrogenase( EC:1.1.1.157 )638721270 9.689579869 11.16334745 2.517 down 0.000105 RRSL_02477 o c ABC type dipeptide transporter638721272 11.91075487 13.18967245 2.199 down 0.0289 RRSL_02480 o c Aconitate hydratase( EC:4.2.1.3 )638721274 13.22552987 14.59854745 2.347 down 0.0109 RRSL_02482 o c Hypothetical Protein638721282 12.26660487 13.85997245 2.735 down 0.0174 RRSL_02490 o c Succinate dehydrogenase flavoprotein subunit( EC:1.3.99.1 )638721283 12.35200487 13.96237245 2.767 down 0.0209 RRSL_02491 o c Succinate dehydrogenase iron-sulfur protein( EC:1.3.5.1,EC:1.3.99.1 )638721284 10.79260487 12.59177245 3.154 down 0.00545 RRSL_02492 o c Hypothetical Protein638721289 11.93160487 13.19837245 2.181 down 0.0159 RRSL_02497 o c Aspartate-semialdehyde dehydrogenase( EC:1.2.1.11 )638721290 11.47810487 12.97949745 2.566 down 0.0177 RRSL_02498 o c Fimbriae V protein638721299 11.31762987 12.46869745 2.013 down 0.0188 RRSL_02509 o c purF PurF( EC:2.4.2.14 )638721378 10.47047987 11.87962245 2.407 down 0.0365 RRSL_01865 o c Cytochrome c4638721386 9.737479869 11.38857245 2.846 down 0.000263 RRSL_01873 o c Diaminopimelate decarboxylase( EC:4.1.1.20 )638721402 8.579504869 10.11237245 2.622 down 0.0147 RRSL_01891 o c toluene tolerance protein TTG2A638721406 10.37415487 11.96494745 2.73 down 0.00587 RRSL_01895 o c toluene tolerance protein TTG2D638721407 10.63307987 12.22507245 2.732 down 0.00552 RRSL_01896 o c toluene tolerance protein TTG2E638721413 9.298729869 10.73444745 2.452 down 0.0133 RRSL_01902 o c Histidinol dehydrogenase( EC:1.1.1.23 )638721416 12.59545487 13.81537245 2.111 down 0.00242 RRSL_01905 o c Aspartokinase( EC:2.7.2.4 )638721442 12.12750487 13.66454745 2.63 down 0.0133 RRSL_01932 o c Transmembrane hypothetical protein638721444 10.05862987 11.38444745 2.272 down 0.00422 RRSL_01934 o c Hypothetical Protein638721468 9.570179869 10.83382245 2.176 down 0.0141 RRSL_01959 o c lolD LolD638721478 8.827654869 10.38172245 2.661 down 0.00392 RRSL_02582 o c Trp repressor binding protein638721485 10.47250487 11.70947245 2.136 down 0.0373 RRSL_02590 o c Chorismate synthase( EC:4.2.3.5 )638721528 13.64810487 14.79564745 2.008 down 0.00301 RRSL_01676 o c Fumarate hydratase( EC:4.2.1.2 )638721635 8.481879869 9.797922449 2.256 down 0.00838 RRSL_01150 o c Holo-[acyl-carrier protein] synthase( EC:2.7.8.7 )638721636 9.697054869 10.90474745 2.093 down 0.0494 RRSL_01151 o c pdxJ PdxJ638721650 11.85615487 13.42184745 2.683 down 0.0228 RRSL_01167 o c Malonyl-CoA-[acyl-carrier-protein] transacylase( EC:2.3.1.39 )638721651 11.91322987 13.13722245 2.117 down 0.0372 RRSL_01168 o c 3-oxoacyl-[acyl-carrier-protein] synthase III( EC:2.3.1.41 )638721652 12.04485487 13.29864745 2.161 down 0.0121 RRSL_01169 o c plsX PlsX638721655 11.12770487 12.49239745 2.334 down 0.0002 RRSL_01172 o c Septum formation protein Maf638721656 8.672029869 10.04952245 2.355 down 0.000181 RRSL_01173 o c Methyltransferase( EC:2.1.1.- )638721669 8.146129869 9.501697449 2.319 down 0.0026 RRSL_01187 o c Hypothetical protein638721671 10.46817987 11.95207245 2.535 down 0.00432 RRSL_01189 o c Bacterial Peptide Chain Release Factor 2 (RF-2)638721673 8.192954869 9.931422449 3.024 down 0.00723 RRSL_01191 o c Sepiapterin reductase( EC:1.1.1.153 )638721721 10.51905487 11.72497245 2.091 down 0.00423 RRSL_01660 o c Arginyl-tRNA synthetase( EC:6.1.1.19 )638721724 11.02372987 12.23752245 2.102 down 0.0078 RRSL_01663 o c Oxidoreductase( EC:1.1.1.- )638721776 11.50742987 12.76969745 2.174 down 0.0057 RRSL_01575 o c Alanine racemase( EC:5.1.1.1 )638721777 9.324379869 10.57819745 2.161 down 0.00416 RRSL_01576 o c DNA repair protein RadA638721826 11.64617987 13.27247245 2.798 down 0.0133 RRSL_02010 o c signal peptide638721854 11.09627987 12.92357245 3.216 down 0.00102 RRSL_02038 o c ATP-dependent protease hslV( EC:3.4.25.- )638721855 9.573229869 11.68249745 3.911 down 0.000663 RRSL_02039 o c heat shock protein chaperone; cpX superfamily638721874 12.00777987 13.56099745 2.66 down 0.00687 RRSL_01406 o c Dihydrolipoamide dehydrogenase( EC:1.8.1.4 )

638721875 12.89337987 14.58157245 2.921 down 0.00103 RRSL_01407 o cDihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex( EC:2.3.1.61 )

638721876 11.32645487 13.10019745 3.099 down 0.00878 RRSL_01408 o c 2-oxoglutarate dehydrogenase E1 component( EC:1.2.4.2 )638721889 12.69325487 13.99959745 2.241 down 0.0315 RRSL_01421 o c Glutamine synthetase( EC:6.3.1.2 )638721929 9.219079869 10.64377245 2.433 down 0.00339 RRSL_01964 o c Dipeptide-binding protein638721935 12.34715487 14.21922245 3.318 down 0.00155 RRSL_01970 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638721936 9.424554869 11.89859745 5.036 down 0.000125 RRSL_01972 o c PTS system, fructose-specific IIBC component( EC:2.7.1.69 )638721937 9.683554869 11.85284745 4.077 down 0.00291 RRSL_01973 o c 1-phosphofructokinase( EC:2.7.1.56 )

638721938 8.333504869 10.70827245 4.701 down 0.000932 RRSL_01974 o cPhosphoenolpyruvate-protein phosphotransferase / Phosphocarrier protein HPr / PTS system, glucose-specific IIA subunit( EC:2.7.1.69,EC:2.7.3.9 )

638721940 9.904904869 11.74222245 3.239 down 0.000412 RRSL_01976 o c anaerobic dehydrogenase638721941 9.237704869 10.49459745 2.166 down 0.0014 RRSL_01977 o c hypothetical protein638721942 10.92040487 12.31244745 2.378 down 0.000184 RRSL_01978 o c Long-chain-fatty-acid--CoA ligase( EC:6.2.1.3 )638721954 10.36735487 11.60699745 2.14 down 0.0107 RRSL_01990 o c UDP-N-acetylmuramoylalanine--D-glutamate ligase( EC:6.3.2.9 )638721994 10.18207987 11.42424745 2.144 down 0.00207 RRSL_01322 o c Protein Translation Elongation Factor Ts (EF-Ts)638722005 10.49520487 11.96607245 2.512 down 0.00771 RRSL_01334 o c dapC DapC( EC:2.6.1.17 )638722013 8.086304869 9.802222449 2.977 down 0.00113 RRSL_01344 o c Hypothetical Protein638722014 7.439329869 8.673297449 2.132 down 0.00785 RRSL_01345 o c D-aminopeptidase( EC:3.4.11.19 )638722015 9.487079869 11.19354745 2.958 down 0.000353 RRSL_01346 o c D-aminopeptidase( EC:3.4.11.19 )638722016 9.686779869 10.96519745 2.198 down 0.014 RRSL_01347 o c dppC DppC638722018 10.33300487 12.23364745 3.384 down 0.00213 RRSL_01349 o c Dipeptide-binding protein638722019 8.123204869 9.990222449 3.306 down 0.00203 RRSL_01350 o c dppF DppF638722020 8.406679869 10.19519745 3.131 down 0.000772 RRSL_01351 o c L-asparaginase( EC:3.5.1.1 )638722021 9.261679869 10.67472245 2.413 down 0.023 RRSL_01352 o c Transcriptional regulator, RpiR family638722057 8.158104869 9.454672449 2.226 down 0.00023 RRSL_01254 o c Xanthine dehydrogenase large subunit( EC:1.1.1.204 )638722059 8.761979869 9.922922449 2.026 down 0.0158 RRSL_01256 o c Adenosine deaminase( EC:3.5.4.4 )638722078 12.07347987 13.30494745 2.128 down 0.0407 RRSL_01276 o c NADP-dependent malic enzyme( EC:1.1.1.40 )638722080 9.862654869 11.81149745 3.499 down 0.00853 RRSL_01279 o c aminopeptidase N (alpha-aminoacyl peptide hydrolase) metalloprotease; pepN( EC:3.4.11.2 )638722081 11.89535487 13.11294745 2.108 down 0.0135 RRSL_01280 o c Fructose-1,6-bisphosphatase( EC:3.1.3.11 )638722130 13.13145487 14.45267245 2.265 down 0.00999 RRSL_01215 o c Argininosuccinate synthase argG( EC:6.3.4.5 )638722133 12.07000487 13.73554745 2.875 down 0.0268 RRSL_01218 o c Hypothetical Protein638722149 11.37502987 12.66949745 2.223 down 0.00612 RRSL_01235 o c Phosphoribosylformylglycinamidine cyclo-ligase( EC:6.3.3.1 )638722151 9.030479869 10.28492245 2.162 down 0.0011 RRSL_01237 o c DnaA-related protein638722153 9.757679869 10.94029745 2.057 down 0.033 RRSL_01239 o c poly(a) polymerase / tRNA nucleotidyltransferase( EC:2.7.7.19,EC:2.7.7.25 )638722167 9.325304869 10.96359745 2.821 down 0.0149 RRSL_01496 o c Hypothetical Protein638722237 14.07342987 15.46949745 2.385 down 0.0014 RRSL_01451 o c Superoxide dismutase( EC:1.15.1.1 )638722261 8.914304869 10.38469745 2.511 down 0.000861 RRSL_01475 o c Hypothetical Protein638722273 13.19780487 14.43674745 2.139 down 0.0497 RRSL_01488 o c Isocitrate dehydrogenase (NADP)( EC:1.1.1.42 )638722299 10.27825487 11.60109745 2.267 down 0.0136 RRSL_01110 o c amiC AmiC( EC:3.5.1.28 )638722320 8.124404869 9.780297449 2.856 down 0.000908 RRSL_00937 o c mexC MexC638722379 11.96882987 13.14397245 2.046 down 0.0056 RRSL_00971 o c Inorganic pyrophosphatase( EC:3.6.1.1 )638722383 11.48045487 13.82627245 4.607 down 0.00111 RRSL_00975 o c hydrogenase cytochrome B-type subunit homolog

638722385 7.784129869 8.982147449 2.079 down 0.0201 RRSL_00978 o cUROPORPHYRINOGEN-III SYNTHASE / Uroporphyrin-III C-methyltransferase( EC:2.1.1.107,EC:4.2.1.75 )

638722386 9.915429869 11.69602245 3.114 down 0.0019 RRSL_00977 o c Phosphoenolpyruvate carboxylase( EC:4.1.1.31 )638722454 8.585504869 9.992647449 2.404 down 0.00512 RRSL_00903 o c Maleylpyruvate isomerase( EC:5.2.1.2,EC:5.2.1.4 )

638722508 10.80472987 12.27872245 2.518 down 0.00225 RRSL_00994 o cphosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase( EC:2.1.2.3,EC:3.5.4.10 )

638722520 10.18170487 11.53744745 2.319 down 0.0163 RRSL_01007 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638722521 8.799779869 10.04969745 2.155 down 0.00482 RRSL_01008 o c 4-hydroxythreonine-4-phosphate dehydrogenase( EC:1.1.1.262 )638722528 9.075329869 10.35609745 2.202 down 0.0121 RRSL_00868 o c ATP-dependent DNA helicase recQ( EC:3.6.1.- )638722535 8.777979869 10.19622245 2.422 down 0.000551 RRSL_00875 o c Hypothetical Protein638722536 12.54515487 13.81737245 2.189 down 0.0479 RRSL_00876 o c DNA-directed RNA polymerase beta chain( EC:2.7.7.6 )638722552 9.781529869 11.05542245 2.191 down 0.0265 RRSL_00658 o c DNA polymerase III, epsilon chain( EC:2.7.7.7 )638722558 11.67365487 13.53807245 3.3 down 0.00652 RRSL_00664 o c Hypothetical protein638722657 13.38947987 14.80632245 2.42 down 0.0168 RRSL_00862 o c DNA-binding protein HU638722761 9.737454869 11.23642245 2.562 down 0.0161 RRSL_00427 o c Hypothetical Protein638722814 7.731504869 9.861647449 3.968 down 0.0024 RRSL_00412 o c conserved hypothetical protein638722815 9.771004869 11.85797245 3.851 down 0.00558 RRSL_00413 o c Hypothetical membrane spanning protein

638722816 11.55672987 13.62839745 3.81 down 0.000257 RRSL_00414 o c lipoprotein LemA638722868 12.42565487 13.86254745 2.454 down 0.00688 RRSL_00616 o c UTP--glucose-1-phosphate uridylyltransferase( EC:2.7.7.9 )638722931 8.663329869 10.24397245 2.711 down 0.0448 RRSL_00303 o c DNA polymerase III subunit gamma/tau( EC:2.7.7.7 )638722948 10.78360487 11.95492245 2.041 down 0.0363 RRSL_00341 o c oxidoreductase, L-aspartate oxidase, nadB2( EC:1.4.3.16 )638722955 9.891179869 11.38109745 2.545 down 0.026 RRSL_00226 o c Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase( EC:2.3.1.129 )638722981 10.89857987 12.19229745 2.222 down 0.0055 RRSL_00266 o c ATP-dependent protease subunit638722982 9.610779869 11.46027245 3.266 down 0.00624 RRSL_00267 o c Glutamate N-acetyltransferase / Amino-acid acetyltransferase( EC:2.3.1.1,EC:2.3.1.35 )638722983 11.45060487 12.69937245 2.154 down 0.0329 RRSL_00268 o c Protein translocase subunit secA638722991 9.006929869 10.28639745 2.2 down 0.00123 RRSL_00182 o c Hypothetical Protein638723021 12.36487987 13.54512245 2.054 down 0.03 RRSL_00208 o c Integration host factor beta-subunit638723027 9.670629869 10.87542245 2.089 down 0.00917 RRSL_00214 o c COME operon protein 1638723030 8.762229869 9.950972449 2.066 down 0.0305 RRSL_00216 o c Acetylspermidine deacetylase( EC:3.5.1.48 )638723047 10.19402987 12.79727245 5.508 down 0.000222 RRSL_00149 o c Glycerol-3-phosphate regulon repressor638723048 9.620654869 12.61027245 7.199 down 0.000961 RRSL_00150 o c Glycerol-3-phosphate dehydrogenase( EC:1.1.99.5 )638723049 9.566329869 11.84727245 4.405 down 0.000244 RRSL_00152 o c Glycerol transport ATP-binding protein638723059 10.78765487 12.10069745 2.252 down 0.0104 RRSL_00147 o c Glutamyl-tRNA synthetase( EC:6.1.1.17 )638723066 11.55060487 12.92032245 2.342 down 0.0129 RRSL_00139 o c Low-affinity inorganic phosphate transporter638723067 12.71355487 14.06717245 2.316 down 0.00182 RRSL_00140 o c Putative pit accessory protein638723098 10.73370487 12.00544745 2.188 down 0.00573 RRSL_00076 o c Undecaprenyl-phosphate alpha-4-amino-L-arabinosyltransferase( EC:2.7.8.- )638723110 12.68385487 13.91364745 2.125 down 0.0154 RRSL_00103 o c Hypothetical Protein638723111 11.24212987 12.67229745 2.442 down 0.00633 RRSL_00083 o c TolQ protein638723112 8.190279869 9.933897449 3.035 down 0.00248 RRSL_00084 o c TolR protein638718797 8.683679869 10.00902245 2.271 down 0.0112 RRSL_04649 o Fic family protein638718825 8.724754869 10.25892245 2.625 down 0.000628 RRSL_04678 o Acriflavin resistance periplasmic protein

638718839 8.993529869 10.18517245 2.07 down 0.00995 RRSL_04693 oType I protein secretion ATP-binding protein / Type I protein secretion transmembrane subunit / Type I secretion processing peptidase

638718889 9.469879869 11.75157245 4.407 down 0.000695 RRSL_04747 o Hypothetical Protein638718890 9.278554869 12.19189745 6.828 down 0.000265 RRSL_04748 o Hypothetical Protein638718891 10.32960487 11.82349745 2.553 down 0.00586 RRSL_04749 o Hypothetical Protein638718892 9.749029869 11.50692245 3.065 down 0.00307 RRSL_04750 o Alpha,alpha-trehalose-phosphate synthase (UDP-forming)( EC:2.4.1.15 )638718893 7.555004869 9.698247449 4.004 down 0.000188 RRSL_04751 o Trehalose-phosphatase( EC:3.1.3.12 )638718898 9.167729869 10.35849745 2.069 down 0.0139 RRSL_04756 o Hypothetical Protein638718924 10.58732987 11.84109745 2.161 down 0.035 RRSL_04785 o Thiamin-phosphate pyrophosphorylase( EC:2.5.1.3 )638718928 10.26862987 11.48534745 2.106 down 0.0133 RRSL_04789 o Hypothetical Protein638718929 7.837354869 9.424972449 2.724 down 0.0124 RRSL_04790 o Hypothetical Protein638718930 10.61190487 11.76454745 2.015 down 0.00789 RRSL_04791 o Hypothetical protein638718983 9.102729869 10.31029745 2.093 down 0.00631 RRSL_04440 o hypothetical protein638719259 9.544104869 11.18639745 2.829 down 0.0209 RRSL_04078 o Hypothetical Protein638719574 8.273429869 9.519072449 2.149 down 0.00816 RRSL_03955 o hypothetical protein638719750 8.601729869 9.780972449 2.052 down 0.0057 RRSL_03535 o Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638719909 10.76085487 12.67994745 3.428 down 0.00148 RRSL_03607 o Hypothetical exported protein638720134 9.801104869 12.70224745 6.771 down 0.0000897 RRSL_03654 o L-serine dehydratase( EC:4.3.1.17 )638720165 11.06160487 12.62942245 2.687 down 0.00508 RRSL_03686 o ATP synthase A chain( EC:3.6.3.14 )638720225 10.01767987 11.74707245 3.005 down 0.00908 RRSL_03389 o Hypothetical Protein638720237 11.47420487 12.92712245 2.481 down 0.00827 RRSL_03401 o Putative integral membrane protein638720238 11.80425487 13.58652245 3.117 down 0.0173 RRSL_03402 o Sulfate transporter638720281 9.939929869 11.59112245 2.847 down 0.00634 RRSL_03025 o Ferric siderophore receptor precursor638720282 8.787729869 11.65392245 6.609 down 0.000917 RRSL_03026 o Cysteine synthase( EC:4.2.99.8 )638720283 7.795904869 11.20697245 9.642 down 0.000183 RRSL_03027 o Ornithine cyclodeaminase( EC:4.3.1.12 )638720284 7.148929869 9.863047449 5.948 down 0.000086 RRSL_03028 o Hypothetical IucC protein( EC:6.- )638720285 8.672729869 10.88362245 4.196 down 0.00124 RRSL_03029 o Transmembrane efflux protein638720286 8.238554869 11.22774745 7.197 down 0.00008 RRSL_03030 o Hypothetical IucA protein( EC:6.- )638720287 8.973304869 11.96809745 7.225 down 0.000386 RRSL_03031 o Hypothetical IucC protein( EC:6.- )638720288 7.543454869 10.31177245 6.175 down 0.000242 RRSL_03032 o 4-hydroxy-2-oxovalerate aldolase( EC:4.1.2.- )638720289 8.329254869 10.24432245 3.418 down 0.00301 RRSL_03033 o ssd Ssd638720290 8.161079869 9.666072449 2.572 down 0.000703 RRSL_03034 o Purine/pyrimidine phosphoribosyl transferase( EC:2.4.2.- )638720294 9.397754869 12.50417245 7.806 down 0.000341 RRSL_03038 o Cyanate lyase( EC:4.2.1.104,EC:4.3.99.1 )

638720299 8.316454869 12.14394745 12.868 down 0.0000126 RRSL_03044 o Hypothetical Protein638720300 10.18407987 11.96107245 3.106 down 0.000944 RRSL_03045 o Transcriptional regulatory protein638720317 8.286129869 9.630247449 2.301 down 0.00108 RRSL_03062 o Hypothetical Protein638720328 9.439354869 10.59024745 2.012 down 0.00303 RRSL_03075 o putative phosphohydrolases, Icc family638720329 10.17427987 11.60682245 2.446 down 0.0395 RRSL_03076 o oxidoreductase cytochrome C oxidase polypeptide.638720335 10.59430487 12.45649745 3.295 down 0.00198 RRSL_03083 o Ribonuclease BN( EC:3.1.- )638720336 7.214679869 9.123372449 3.403 down 0.00271 RRSL_03084 o Hypothetical Protein638720337 13.00730487 14.89912245 3.363 down 0.00107 RRSL_03085 o Hypothetical Protein638720338 12.06995487 14.46944745 4.782 down 0.00116 RRSL_03086 o Two-component response regulator638720339 12.87190487 14.31404745 2.463 down 0.0146 RRSL_03087 o probable sigma-54 interacting protein638720342 10.67170487 12.43924745 3.086 down 0.00889 RRSL_03091 o Hypothetical Protein638720344 9.428579869 10.97139745 2.641 down 0.00207 RRSL_03093 o Hypothetical Protein638720345 9.296879869 11.20534745 3.402 down 0.00293 RRSL_03094 o Hypothetical Protein638720350 10.66587987 12.17979745 2.588 down 0.0497 RRSL_02928 o Ribonuclease P protein component( EC:3.1.26.5 )638720351 11.59565487 12.84679745 2.157 down 0.0179 RRSL_02929 o Hypothetical cytosolic protein638720352 12.43855487 13.78807245 2.309 down 0.0112 RRSL_02930 o 60 kDa inner membrane protein YIDC638720416 7.547079869 8.807297449 2.171 down 0.00802 RRSL_02998 o Protoporphyrin-IX magnesium chelatase subunit D638720418 9.264429869 10.55172245 2.212 down 0.00738 RRSL_03000 o Ferredoxin, 2Fe-2s638720535 7.946204869 9.217222449 2.187 down 0.00342 RRSL_02275 o Hypothetical protein638720537 12.28467987 13.43349745 2.009 down 0.00875 RRSL_02277 o Transcriptional regulator, AraC family638720538 9.218754869 10.48284745 2.177 down 0.0143 RRSL_02278 o Acyl-CoA dehydrogenase, short-chain specific( EC:1.3.99.2 )638720539 11.42925487 13.68509745 4.329 down 0.000124 RRSL_02279 o Integral membrane protein638720540 12.32447987 14.45687245 3.974 down 0.000358 RRSL_02280 o Transcriptional regulator638720541 12.13490487 16.22592245 15.447 down 0.000201 RRSL_02281 o Fumarylacetoacetase( EC:3.7.1.2 )638720542 11.94170487 16.07867245 15.947 down 0.000117 RRSL_02282 o Homogentisate 1,2-dioxygenase( EC:1.13.11.5 )638720545 10.66130487 11.84634745 2.061 down 0.0303 RRSL_02287 o 4-hydroxyphenylacetate 1-monooxygenase( EC:1.14.13.18 )638720546 9.346029869 11.82077245 5.038 down 0.00485 RRSL_02288 o Beta-lactamase, type II( EC:3.5.2.6 )638720607 11.14622987 12.38899745 2.145 down 0.0128 RRSL_02923 o hypothetical protein638720657 10.65230487 12.06237245 2.408 down 0.0151 RRSL_02836 o Usf protein638720658 7.963054869 9.334497449 2.345 down 0.0133 RRSL_02837 o transmembrane hypothetical protein638720763 8.510779869 9.745747449 2.133 down 0.0343 RRSL_02053 o dnaK DnaK638720866 10.29782987 11.62797245 2.279 down 0.000915 RRSL_02349 o Outer membrane porin protein 32 precursor638721006 10.39927987 12.41982245 3.677 down 0.00643 RRSL_02226 o Hypothetical Protein638721011 11.41607987 13.52359745 3.906 down 0.00132 RRSL_02231 o Cytochrome P-450638721080 8.059729869 9.925272449 3.303 down 0.00141 RRSL_03134 o nac Nac638721081 8.138829869 10.10267245 3.536 down 0.000079 RRSL_03135 o Hypothetical Protein638721096 8.952779869 10.70037245 3.043 down 0.0214 RRSL_03152 o kdpE KdpE638721097 10.90085487 13.43969745 5.267 down 0.00571 RRSL_03153 o Tricarboxylate-binding protein638721108 9.760404869 12.27919745 5.194 down 0.000179 RRSL_03167 o NAD-dependent oxidoreductase638721110 10.73675487 12.02424745 2.212 down 0.0317 RRSL_03169 o probable lipoprotein638721124 8.343229869 9.675347449 2.282 down 0.000866 RRSL_03184 o putative hemagglutinin-related transmembrane protein638721213 9.754254869 11.21219745 2.49 down 0.0117 RRSL_02541 o Transcriptional regulator, LysR family638721245 6.923954869 8.528322449 2.756 down 0.00177 RRSL_02451 o Urease beta subunit( EC:3.5.1.5 )638721246 10.41017987 11.80384745 2.381 down 0.0022 RRSL_02452 o Urease alpha subunit( EC:3.5.1.5 )638721247 8.460604869 9.733097449 2.189 down 0.0119 RRSL_02453 o ureE UreE638721248 7.273054869 8.680222449 2.404 down 0.00233 RRSL_02454 o ureF UreF638721249 8.959829869 10.27952245 2.262 down 0.00189 RRSL_02455 o ureG UreG638721271 11.86595487 13.02407245 2.022 down 0.0143 RRSL_02479 o Hypothetical Protein638721324 10.71665487 11.86397245 2.007 down 0.0303 RRSL_01752 o Hypothetical Protein638721326 10.56407987 11.98692245 2.43 down 0.00592 RRSL_01754 o probable transmembrane638721387 9.627179869 11.54412245 3.422 down 0.000866 RRSL_01874 o Hypothetical protein638721492 9.933954869 11.12997245 2.076 down 0.0119 RRSL_02597 o 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase( EC:3.7.1.- )638721545 8.348004869 9.855322449 2.576 down 0.00179 RRSL_01693 o probable glycogen synthase, glgA( EC:2.4.1.21 )638721558 10.38475487 12.00487245 2.786 down 0.00149 RRSL_01707 o Hypothetical Protein638721568 11.39290487 12.54989745 2.021 down 0.00581 RRSL_01717 o Periplasmic glucans biosynthesis protein mdoG precursor638721587 10.55005487 12.18342245 2.812 down 0.0179 RRSL_01785 o Hypothetical protein638721615 10.55637987 12.05384745 2.559 down 0.00918 RRSL_01815 o Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)( EC:3.6.1.17 )

638721626 8.184879869 9.954647449 3.091 down 0.00314 RRSL_01826 o Hypothetical Protein638721627 10.60862987 12.33282245 2.994 down 0.00491 RRSL_01827 o Mechanosensitive ion channel638721791 10.82872987 11.98929745 2.026 down 0.00538 RRSL_01594 o Exo-poly-alpha-D-galacturonosidase precursor( EC:3.2.1.82 )638721890 8.776479869 9.990047449 2.102 down 0.0366 RRSL_01422 o sulfide dehydrogenase precursor638721914 10.16257987 11.42244745 2.17 down 0.00163 RRSL_01375 o Putative lipoprotein638722067 9.771129869 11.00977245 2.139 down 0.00155 RRSL_01265 o Dehydrogenase protein DltE638722185 10.00910487 11.18702245 2.05 down 0.00709 RRSL_01514 o Beta-hexosaminidase( EC:3.2.1.52 )638722235 7.948929869 9.360597449 2.411 down 0.00264 RRSL_01320 o Signal peptidase I( EC:3.4.21.89 )638722304 12.15570487 14.36044745 4.178 down 0.000289 RRSL_00920 o Molybdopterin-guanine dinucleotide biosynthesis protein A638722305 9.031079869 12.65357245 11.164 down 0.000357 RRSL_00921 o Hypothetical Protein638722339 8.899779869 10.14627245 2.15 down 0.00581 RRSL_00815 o Formate dehydrogenase alpha subunit homolog638722340 10.12730487 11.39999745 2.19 down 0.0205 RRSL_00816 o Oxalate/formate antiporter638722600 8.463004869 9.750197449 2.212 down 0.00285 RRSL_00444 o Transporter, drug/metabolite exporter family638722607 7.819179869 9.336197449 2.594 down 0.00236 RRSL_00452 o Hypothetical Protein638722683 9.451254869 11.00832245 2.667 down 0.0213 RRSL_00745 o Hypothetical Protein638722855 10.06832987 11.21869745 2.012 down 0.000962 RRSL_00558 o Hypothetical Protein638722856 7.967979869 9.278847449 2.248 down 0.00708 RRSL_00559 o Rrf2 family protein638722857 7.977879869 9.425772449 2.472 down 0.00592 RRSL_00560 o putative nucleoside-diphosphate-sugar epimerases638722858 8.595254869 9.756247449 2.026 down 0.0145 RRSL_00562 o Hypothetical Protein638722859 11.41660487 12.91199745 2.555 down 0.00182 RRSL_00563 o Transcriptional regulatory protein638722867 10.12120487 11.33539745 2.103 down 0.0185 RRSL_00615 o Hypothetical Protein638722971 13.11837987 14.76327245 2.834 down 0.0434 RRSL_00246 o Hypothetical Protein638723050 10.97637987 13.17762245 4.168 down 0.00432 RRSL_00153 o Glycerol transport system permease protein638723051 11.29917987 13.19879745 3.382 down 0.0144 RRSL_00154 o Hypothetical Protein638723052 8.832879869 11.14757245 4.509 down 0.00133 RRSL_00155 o Glycerol ABC transporter-associated membrane protein638723053 10.79210487 13.07349745 4.406 down 0.000088 RRSL_00156 o Glycerol-binding protein638723077 11.03337987 12.25319745 2.111 down 0.0113 RRSL_00114 o PhnA protein638723088 11.25050487 13.45282245 4.171 down 0.0000967 RRSL_00106 o Ferredoxin638718798 8.897029869 10.86472245 3.545 down 0.00355 RRSL_04650 Hypothetical Protein638718846 10.68995487 12.15789745 2.507 down 0.018 RRSL_04700 Hypothetical Protein638718847 10.51360487 12.15632245 2.83 down 0.0125 RRSL_04701 Hypothetical Protein638718982 8.719754869 10.23229745 2.586 down 0.00568 RRSL_04437 hypothetical protein638719244 11.35645487 13.56969745 4.203 down 0.00012 RRSL_04062 Hypothetical Protein638719252 9.881754869 11.35787245 2.521 down 0.0107 RRSL_04070 Hypothetical Protein638719261 8.670229869 10.15107245 2.53 down 0.000848 RRSL_04080 Hypothetical protein638719576 9.959529869 11.70632245 3.042 down 0.000627 RRSL_03957 hypothetical protein638719759 8.412379869 9.585322449 2.043 down 0.000133 RRSL_03544 Hypothetical Protein638719852 8.978129869 10.17124745 2.072 down 0.0136 RRSL_03818 Tartrate dehydrogenase( EC:1.1.1.93 )638720178 8.677879869 10.19604745 2.596 down 0.013 RRSL_03699 Hypothetical Protein638720426 11.80062987 13.27104745 2.511 down 0.000398 RRSL_03188 dnaJ DnaJ638720573 10.29085487 11.58302245 2.219 down 0.021 RRSL_02888 hypothetical protein638720578 9.525729869 10.81084745 2.209 down 0.00237 RRSL_02892 hypothetical protein638720747 11.35650487 12.61554745 2.169 down 0.00322 RRSL_02779 Hypothetical Protein638720928 11.27222987 12.50442245 2.129 down 0.0191 RRSL_02417 DNA-binding protein HU638720930 8.170029869 9.799222449 2.804 down 0.00196 RRSL_02419 Hypothetical Protein638720931 8.115254869 9.580247449 2.502 down 0.0146 RRSL_02420 Conserved hypothetical protein638721007 9.036154869 10.90294745 3.306 down 0.00015 RRSL_02227 D-alanine aminotransferase( EC:2.6.1.21 )638721207 10.31465487 11.66242245 2.307 down 0.0231 RRSL_02535 hypothetical protein638721218 7.220204869 8.753872449 2.624 down 0.00242 RRSL_02545 hypothetical protein638721343 10.91750487 12.08832245 2.04 down 0.0119 RRSL_01774 Collagen alpha 2(I) chain precursor638721412 9.768904869 10.95669745 2.064 down 0.00631 RRSL_01901 ATP phosphoribosyltransferase( EC:2.4.2.17 )638721430 10.39785487 11.58754745 2.067 down 0.0401 RRSL_01919 Hypothetical Protein638721507 8.448904869 9.747772449 2.23 down 0.0323 RRSL_02611 Putative resolvase638721672 8.351179869 10.48639745 3.982 down 0.00335 RRSL_01190 Hypothetical Protein638721719 10.09662987 11.65834745 2.675 down 0.0139 RRSL_01658 Hypothetical Protein638721734 10.54967987 11.89217245 2.298 down 0.00995 RRSL_01673 Hypothetical Protein638721904 8.723254869 10.40707245 2.912 down 0.0158 RRSL_01364 Molybdopterin biosynthesis MoeB protein

638721905 10.42880487 12.25092245 3.205 down 0.0326 RRSL_01365 MEC+638721906 9.072229869 10.93522245 3.297 down 0.0173 RRSL_01366 ThiS family protein638721908 8.297329869 10.00839745 2.967 down 0.011 RRSL_01368 2,3-dihydroxybenzoate-AMP ligase( EC:2.7.7.58 )638721911 9.707654869 11.08287245 2.351 down 0.0285 RRSL_01371 Unsaturated glucuronyl hydrolase( EC:3.2.1.- )638721912 9.384304869 11.49429745 3.913 down 0.00822 RRSL_01372 Hypothetical Protein638721913 9.208804869 11.12264745 3.415 down 0.00533 RRSL_01373 Possible TonB-dependent receptor638721962 8.978479869 10.68424745 2.956 down 0.0156 RRSL_01998 hypothetical protein638722011 9.714979869 11.02457245 2.246 down 0.000257 RRSL_01342 Membrane-fusion protein (Cell envelope biogenesis, outer membrane)638722123 9.519279869 10.71999745 2.083 down 0.0159 RRSL_01208 Hypothetical Protein638722160 10.57245487 12.14074745 2.688 down 0.00267 RRSL_01246 dnaJ DnaJ638722161 9.951879869 11.92017245 3.547 down 0.000866 RRSL_01247 Chaperone protein dnaJ638722324 10.25480487 11.51892245 2.177 down 0.0265 RRSL_00941 Hypothetical Protein638722356 10.14847987 11.37417245 2.119 down 0.00267 RRSL_00833 Hypothetical Protein638722471 13.75250487 15.24494745 2.55 down 0.0135 RRSL_RNA018 ( tRNA )638722679 10.22850487 11.57469745 2.304 down 0.0226 RRSL_00549 pilZ PilZ638722682 9.422904869 12.26262245 6.489 down 0.00612 RRSL_00744 Porin638722907 9.763354869 11.07382245 2.248 down 0.0427 RRSL_00314 Tryptophan synthase beta chain( EC:4.2.1.20 )638722933 9.548604869 10.87837245 2.278 down 0.0467 RRSL_00305 Hypothetical protein

638723041 11.14552987 12.91462245 3.089 down 0.00339 RRSL_00204Dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex( EC:2.3.1.61 )

638723100 6.895454869 8.268747449 2.348 down 0.00259 RRSL_00078 UDP-4-amino-4-deoxy-L-arabinose N-formyltransferase( EC:2.1.2.- )638718831 8.779604869 9.394122449 1.387 down 0.0259 RRSL_04684 o c 3,4-dihydroxy-2-butanone-4-phosphate synthase( EC:4.1.2.- )638718832 11.75902987 11.38099745 1.433 up 0.0703 RRSL_04685 o c Gluconate permease638718834 8.317229869 8.851122449 1.312 down 0.0294 RRSL_04688 o c D-aminoacylase( EC:3.5.1.81 )638718836 13.01012987 11.82207245 2.513 up 0.0748 RRSL_04690 o c D-serine dehydratase( EC:4.2.1.14 )638718854 10.12615487 10.28004745 1.008 down 0.953 RRSL_04710 o c Acid phosphatase( EC:3.1.3.2 )638718875 9.975129869 10.46954745 1.276 down 0.224 RRSL_04732 o c Glutaminase( EC:3.5.1.2 )638718883 8.338054869 8.501472449 1.015 down 0.96 RRSL_04740 o c Transmembrane multidrug-efflux system lipoprotein638718884 7.569404869 8.349922449 1.557 down 0.00878 RRSL_04741 o c Probable transmembrane multidrug efflux system protein638718897 10.81090487 11.83359745 1.841 down 0.0117 RRSL_04755 o c UDP-glucose 4-epimerase( EC:5.1.3.2 )638718910 10.33672987 9.567297449 1.88 up 0.00918 RRSL_04769 o c Alternative cytochrome C oxidase polypeptide II( EC:1.9.3.1 )638718933 13.92807987 13.73867245 1.257 up 0.0458 RRSL_04388 o c D-ribose-binding protein638718934 8.762229869 8.647597449 1.194 up 0.347 RRSL_04389 o c Transporter638718936 10.41327987 9.561422449 1.991 up 0.0519 RRSL_04391 o c Transcriptional regulator, LacI family638718938 10.96180487 10.30204745 1.742 up 0.0354 RRSL_04393 o c Site-specific recombinase638718939 9.794454869 10.26679745 1.257 down 0.0612 RRSL_04394 o c Excinuclease ABC subunit B638718942 9.347929869 9.545897449 1.039 down 0.695 RRSL_04397 o c Transcriptional regulator, TetR family638718946 9.377829869 8.652147449 1.824 up 0.0963 RRSL_04402 o c Transporter, drug/metabolite exporter family638718947 13.12412987 14.08474745 1.764 down 0.0169 RRSL_04403 o c hypothetical protein638718948 14.61077987 14.97907245 1.17 down 0.246 RRSL_04404 o c Cytochrome c-554(548)638718949 11.24582987 10.82064745 1.481 up 0.000382 RRSL_04405 o c ATP-dependent protease subunit638718950 10.42515487 10.31437245 1.191 up 0.107 RRSL_04406 o c hypothetical protein638718952 8.501779869 8.985172449 1.267 down 0.108 RRSL_04408 o c Spermidine synthase( EC:2.5.1.16 )638718953 12.02535487 11.81869745 1.273 up 0.485 RRSL_04409 o c Integral membrane protein638718958 10.23200487 10.42887245 1.038 down 0.533 RRSL_04414 o c Transcriptional regulatory protein638718961 13.89532987 13.86049745 1.13 up 0.463 RRSL_04417 o c Glutathione S-transferase( EC:2.5.1.18 )638718962 9.114254869 10.00197245 1.677 down 0.0159 RRSL_04418 o c hypothetical protein638718963 9.481404869 10.39589745 1.708 down 0.0139 RRSL_04419 o c hypothetical protein638718965 11.41292987 10.98254745 1.486 up 0.156 RRSL_04421 o c L-lactate permease638718966 10.07842987 10.05632245 1.12 up 0.536 RRSL_04422 o c Transporter638718967 8.904904869 9.385947449 1.265 down 0.126 RRSL_04423 o c Transporter638718968 10.21897987 11.35507245 1.992 down 0.00604 RRSL_04424 o c Topoisomerase IV subunit A638718969 11.42260487 11.80509745 1.181 down 0.0146 RRSL_04425 o c Soluble lytic murein transglycosylase( EC:3.2.1.- )638718972 9.433529869 9.920497449 1.27 down 0.114 RRSL_04428 o c uup Uup638718973 11.75190487 11.29189745 1.517 up 0.0066 RRSL_04429 o c hypothetical protein638718974 11.09452987 10.56092245 1.596 up 0.0115 RRSL_04430 o c Glutamate/aspartate-binding protein638718975 11.05227987 11.14399745 1.035 up 0.887 RRSL_04431 o c hypothetical protein

638718991 13.05232987 12.28862245 1.873 up 0.191 RRSL_04449 o c ATP-dependent RNA helicase638718994 10.63147987 11.38247245 1.525 down 0.076 RRSL_04452 o c Integral membrane protein638718995 12.37480487 12.85804745 1.267 down 0.154 RRSL_04454 o c Threonine dehydratase( EC:4.2.1.16 )638718996 10.32942987 11.33647245 1.821 down 0.0158 RRSL_04453 o c Thymidylate synthase( EC:2.1.1.45 )638718997 7.852529869 8.859947449 1.822 down 0.00864 RRSL_04455 o c Dihydrofolate reductase( EC:1.5.1.3 )638718998 12.61782987 13.22847245 1.384 down 0.0434 RRSL_04456 o c PmbA protein638718999 12.82345487 12.45309745 1.426 up 0.185 RRSL_04457 o c hypothetical protein638719001 12.04347987 11.02212245 2.239 up 0.0601 RRSL_04460 o c Oligoribonuclease( EC:3.1.- )638719002 11.48512987 12.40767245 1.718 down 0.00109 RRSL_04459 o c potential CaaX prenyl protease 1( EC:3.4.24.- )638719003 10.64300487 11.50447245 1.646 down 0.0422 RRSL_04461 o c GTPase( EC:3.6.1.- )638719004 7.347579869 8.396797449 1.875 down 0.0406 RRSL_04462 o c hypothetical protein638719005 10.46020487 11.08639745 1.399 down 0.019 RRSL_04463 o c CbiB protein638719006 10.98742987 11.52249745 1.313 down 0.0983 RRSL_04464 o c Conserved hypothetical protein638719007 15.44072987 16.00357245 1.338 down 0.0362 RRSL_04465 o c LSU ribosomal protein L19P638719008 12.99772987 14.07059745 1.906 down 0.0305 RRSL_04466 o c hypothetical protein( EC:2.1.1.31 )638719010 9.846829869 9.703497449 1.218 up 0.382 RRSL_04468 o c L-sorbosone dehydrogenase (FAD)( EC:1.2.99.- )638719011 9.118254869 9.117497449 1.103 up 0.68 RRSL_04470 o c hypothetical protein638719013 12.51980487 13.33387245 1.593 down 0.0281 RRSL_04472 o c hypothetical protein638719014 8.225829869 9.096397449 1.657 down 0.00592 RRSL_04473 o c Transporter638719015 10.97260487 11.86834745 1.686 down 0.0382 RRSL_04474 o c Leucine-responsive regulatory protein638719019 9.836254869 9.099097449 1.838 up 0.0427 RRSL_04478 o c hypothetical signal protein638719020 8.725279869 8.385272449 1.396 up 0.344 RRSL_04479 o c probable transmembrane ABC transporter protein638719021 8.574029869 7.768347449 1.928 up 0.0566 RRSL_04480 o c ABC transporter ATP-binding protein638719050 13.58865487 12.95082245 1.716 up 0.0746 RRSL_04511 o c LacX protein638719051 10.43355487 10.96129745 1.306 down 0.255 RRSL_04512 o c hypothetical protein638719052 9.607479869 9.652797449 1.069 up 0.775 RRSL_04513 o c DNA polymerase IV( EC:2.7.7.7 )638719053 9.866904869 10.86354745 1.808 down 0.0249 RRSL_04514 o c Amino acid permease638719054 9.009229869 9.675947449 1.438 down 0.0488 RRSL_04515 o c hypothetical protein638719055 12.90220487 13.36062245 1.245 down 0.527 RRSL_04516 o c hypothetical protein638719056 8.833254869 9.534822449 1.474 down 0.179 RRSL_04517 o c 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase( EC:4.1.2.-,EC:4.1.2.20 )638719057 10.80220487 11.74464745 1.742 down 0.0157 RRSL_04518 o c Transcriptional regulator, MarR family638719058 11.33347987 11.52182245 1.032 down 0.767 RRSL_04519 o c Exodeoxyribonuclease III( EC:3.1.11.2 )638719059 9.207479869 9.513772449 1.12 down 0.327 RRSL_04520 o c Cytosine deaminase( EC:3.5.4.1 )638719062 11.05647987 11.88787245 1.612 down 0.0195 RRSL_04523 o c transcriptional regulator/response regulator LuxR family638719063 9.927004869 9.746697449 1.25 up 0.0793 RRSL_04524 o c Sensor protein fixL( EC:2.7.3.- )638719069 16.73817987 16.86319745 1.011 up 0.833 RRSL_04530 o c granule-associated protein638719070 9.200154869 9.031747449 1.239 up 0.203 RRSL_04531 o c Deacetylase638719072 9.059054869 9.798047449 1.512 down 0.0173 RRSL_04533 o c hypothetical protein638719073 12.60762987 13.31609745 1.481 down 0.0143 RRSL_04534 o c D-alanyl-D-alanine-endopeptidase( EC:3.4.99.- )638719074 11.46252987 9.131122449 5.552 up 0.0582 RRSL_04535 o c Transcriptional regulator, IclR family638719075 11.38422987 11.72094745 1.144 down 0.451 RRSL_04536 o c Cysteine-rich domain of 2-hydroxy-acid oxidase GlcF homolog638719076 10.13952987 10.14729745 1.097 up 0.663 RRSL_04537 o c iron-sulfur cluster-binding protein638719077 8.977704869 9.711072449 1.506 down 0.2 RRSL_04538 o c hypothetical protein638719078 12.41205487 13.00947245 1.371 down 0.0706 RRSL_04539 o c hypothetical protein638719079 12.04867987 12.08624745 1.074 up 0.701 RRSL_04541 o c Arginine-tRNA-protein transferase( EC:2.3.2.8 )638719080 10.68705487 11.12999745 1.232 down 0.417 RRSL_04542 o c Leucyl/phenylalanyl-tRNA--protein transferase( EC:2.3.2.-,EC:2.3.2.6 )638719081 9.842679869 10.76127245 1.713 down 0.152 RRSL_04543 o c Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase)( EC:3.6.1.- )638719083 10.17747987 11.17749745 1.812 down 0.0106 RRSL_04544 o c Dihydroorotate dehydrogenase( EC:1.3.3.1 )638719084 10.14635487 11.22634745 1.916 down 0.0571 RRSL_04545 o c hypothetical protein638719085 10.53567987 10.54117245 1.099 up 0.195 RRSL_04546 o c Kup system potassium uptake protein638719089 8.557629869 9.222222449 1.436 down 0.0635 RRSL_04549 o c ATP-dependent helicase, DinG family638719090 14.26727987 14.63022245 1.165 down 0.204 RRSL_04552 o c transmembrane protein638719091 13.64087987 13.79897245 1.011 down 0.902 RRSL_04551 o c Ribosomal large subunit pseudouridine synthase D( EC:4.2.1.70 )638719092 9.638679869 10.35774745 1.492 down 0.135 RRSL_04553 o c hypothetical cytosolic protein638719093 10.87245487 11.14497245 1.094 down 0.557 RRSL_04554 o c hypothetical protein638719098 10.15075487 10.89984745 1.523 down 0.00791 RRSL_04559 o c tRNA-dihydrouridine synthase638719099 11.11585487 11.81637245 1.473 down 0.0468 RRSL_04560 o c Fe-S OXIDOREDUCTASE( EC:1.8.- )

638719100 10.95450487 10.91579745 1.133 up 0.455 RRSL_04561 o c 3-ketoacyl-CoA thiolase( EC:2.3.1.16,EC:2.3.1.9 )638719101 7.921554869 8.228347449 1.121 down 0.597 RRSL_04562 o c hypothetical protein638719102 10.85660487 11.46079745 1.377 down 0.0618 RRSL_04563 o c Cystathionine beta-lyase( EC:4.4.1.8 )638719105 8.541454869 9.543997449 1.816 down 0.00593 RRSL_04566 o c Acetylornithine deacetylase( EC:3.5.1.16 )638719106 10.07210487 10.37837245 1.12 down 0.576 RRSL_04568 o c Transcription-repair coupling factor638719107 9.875504869 10.77257245 1.688 down 0.0214 RRSL_04569 o c 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase( EC:4.6.1.12 )638719108 10.83967987 9.997947449 1.977 up 0.0863 RRSL_04570 o c AhpD protein638719110 9.435229869 10.10684745 1.443 down 0.00653 RRSL_04573 o c Osmolarity sensor protein envZ( EC:2.7.3.- )638719111 11.67630487 12.70329745 1.847 down 0.00801 RRSL_04574 o c RisA638719113 11.84115487 11.39999745 1.497 up 0.0537 RRSL_04576 o c hypothetical cytosolic protein638719114 11.65487987 11.14284745 1.573 up 0.0129 RRSL_04577 o c GLUCOSE-6-PHOSPHATE DEHYDROGENASE (coenzyme F420)( EC:1.1.99.- )638719115 9.939179869 10.61394745 1.447 down 0.104 RRSL_04578 o c Phytoene synthase( EC:2.5.1.32 )638719117 7.733279869 8.432722449 1.471 down 0.00386 RRSL_04580 o c transmembrane protein drug efflux protein638719120 7.246179869 7.399047449 1.007 down 0.974 RRSL_04582 o c hypothetical protein

638719121 8.868479869 9.268122449 1.195 down 0.201 RRSL_04583 o ctRNA (5-aminomethyl-2-thiouridylate) methyltransferase / tRNA (5-carboxymethylaminomethyl-2-thiouridylate) oxidase TrmC( EC:2.1.1.- )

638719122 14.98750487 15.77439745 1.563 down 0.00903 RRSL_04584 o c Trigger factor, ppiase( EC:5.2.1.8 )638719124 14.63032987 14.37437245 1.317 up 0.0319 RRSL_04586 o c clpX ClpX638719125 14.03235487 14.43529745 1.198 down 0.318 RRSL_04587 o c ATP-dependent protease LA( EC:3.4.21.53 )638719126 9.565829869 9.522722449 1.136 up 0.567 RRSL_04588 o c DNA-binding protein HU638719136 8.313704869 8.598172449 1.104 down 0.378 RRSL_04283 o c Adenylylsulfate kinase( EC:2.7.1.25 )638719140 13.20327987 13.72292245 1.299 down 0.27 RRSL_04288 o c Endoglucanase precursor( EC:3.2.1.4 )

638719146 13.10550487 14.14999745 1.869 down 0.0034 RRSL_04296 o cGlucosamine-1-phosphate acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase( EC:2.3.1.-,EC:2.7.7.23 )

638719154 7.253079869 7.558472449 1.12 down 0.299 RRSL_04304 o c oprM OprM638719155 8.635004869 8.370747449 1.324 up 0.118 RRSL_04305 o c ABC-type multidrug transport system, permease component638719156 7.758929869 7.474947449 1.343 up 0.199 RRSL_04306 o c ABC transporter ATP-binding protein638719158 7.694029869 8.345172449 1.423 down 0.0289 RRSL_04308 o c Transcriptional regulator, TetR family638719159 8.216479869 8.104747449 1.192 up 0.302 RRSL_04309 o c piperideine-6-carboxylate dehydrogenase( EC:1.2.1.- )638719160 8.091429869 8.466897449 1.175 down 0.107 RRSL_04310 o c Transcriptional regulatory protein638719161 10.30562987 10.47969745 1.022 down 0.933 RRSL_04311 o c Ornithine aminotransferase( EC:2.6.1.13 )638719162 9.335854869 9.533897449 1.039 down 0.887 RRSL_04312 o c Arginase( EC:3.5.3.1 )638719163 12.28452987 12.73717245 1.24 down 0.0507 RRSL_04313 o c Dihydroneopterin aldolase( EC:4.1.2.25 )638719164 10.92557987 10.76792245 1.23 up 0.571 RRSL_04314 o c Hypothetical cytosolic protein638719165 10.45102987 10.08339745 1.423 up 0.392 RRSL_04317 o c AmpG protein638719166 10.43895487 9.029897449 2.929 up 0.0774 RRSL_04316 o c Zinc metalloprotease( EC:3.4.24.- )638719167 10.74417987 9.904697449 1.974 up 0.167 RRSL_04318 o c Transporter, drug/metabolite exporter family638719168 8.022254869 7.432872449 1.659 up 0.148 RRSL_04319 o c Hypothetical Protein638719169 7.862329869 7.949047449 1.038 up 0.866 RRSL_04320 o c Transcriptional regulator, MarR family638719171 10.49660487 9.477622449 2.235 up 0.11 RRSL_04322 o c Hypothetical Protein638719172 10.80497987 12.00374745 2.08 down 0.0632 RRSL_04323 o c Integral membrane protein638719177 11.23277987 11.94362245 1.483 down 0.00366 RRSL_04328 o c Hypothetical Transmembrane Protein638719178 13.72090487 13.45837245 1.323 up 0.167 RRSL_04329 o c Orotate phosphoribosyltransferase( EC:2.4.2.10 )638719179 11.98285487 12.10897245 1.01 up 0.958 RRSL_04331 o c Hypothetical protein638719180 10.68865487 11.48247245 1.571 down 0.00889 RRSL_04332 o c Diaminopimelate epimerase( EC:5.1.1.7 )638719181 10.29195487 11.00427245 1.485 down 0.0104 RRSL_04333 o c Lipid A biosynthesis lauroyl acyltransferase( EC:2.3.1.- )638719183 13.73490487 13.84889745 1.019 up 0.829 RRSL_04335 o c S-adenosylmethionine synthetase( EC:2.5.1.6 )638719186 8.662029869 8.148772449 1.574 up 0.0269 RRSL_04339 o c PAP2 family protein638719187 10.35747987 9.224172449 2.419 up 0.0915 RRSL_04340 o c Transporter638719188 9.433479869 9.637722449 1.044 down 0.794 RRSL_04341 o c Glutathione S-transferase( EC:2.5.1.18 )638719195 9.399279869 8.911072449 1.547 up 0.0981 RRSL_04348 o c Polyethylene glycol dehydrogenase( EC:1.1.99.20 )638719198 8.444554869 8.941922449 1.279 down 0.0742 RRSL_04351 o c Acyl-CoA dehydrogenase( EC:1.3.99.3 )638719199 9.931454869 11.03024745 1.941 down 0.00691 RRSL_04352 o c Acetyltransferase( EC:2.3.1.- )638719204 9.817379869 10.51389745 1.468 down 0.0751 RRSL_04357 o c Hypothetical Protein638719209 9.431479869 8.744247449 1.776 up 0.0146 RRSL_04365 o c PhnB protein638719212 9.249054869 9.793897449 1.322 down 0.0186 RRSL_04368 o c Hypothetical Protein638719213 9.926479869 10.62689745 1.472 down 0.0031 RRSL_04369 o c Alkaline phosphatase( EC:3.1.3.1 )

638719214 9.351479869 9.847047449 1.277 down 0.0254 RRSL_04370 o c Alkaline phosphatase( EC:3.1.3.1 )638719215 13.64707987 13.85174745 1.044 down 0.586 RRSL_04371 o c Adenosylhomocysteinase( EC:3.3.1.1 )638719216 13.32590487 13.31559745 1.111 up 0.444 RRSL_04372 o c Integral membrane protein638719217 9.494654869 10.15332245 1.43 down 0.0652 RRSL_04373 o c Methylenetetrahydrofolate reductase( EC:1.5.1.20 )638719218 7.396704869 8.015022449 1.391 down 0.0561 RRSL_04374 o c Hypothetical Protein638719220 9.875679869 9.541672449 1.39 up 0.0718 RRSL_04377 o c 5-formyltetrahydrofolate cyclo-ligase( EC:6.3.3.2 )638719222 9.048829869 8.271022449 1.891 up 0.0898 RRSL_04378 o c NADH-ubiquinone oxidoreductase( EC:1.6.5.3,EC:1.6.99.3 )638719226 9.355154869 9.170347449 1.253 up 0.0906 RRSL_04382 o c Glutamate/aspartate-binding protein638719227 8.793954869 9.099222449 1.12 down 0.61 RRSL_04383 o c Hypothetical cytosolic protein638719228 7.553879869 8.123122449 1.344 down 0.113 RRSL_04384 o c COG0161 adenosylmethionine 8-amino-7-oxonoanoate aminotransferase( EC:2.6.1.- )638719229 8.071254869 8.128047449 1.06 up 0.829 RRSL_04385 o c Transcriptional regulator, RpiR family638719249 8.746154869 8.844247449 1.03 up 0.878 RRSL_04067 o c Probable transmembrane methyl-accepting chemotaxis protein638719254 10.22737987 10.38592245 1.011 down 0.907 RRSL_04073 o c Paraquat-inducible protein A638719255 9.875729869 10.09394745 1.054 down 0.549 RRSL_04074 o c Paraquat-inducible protein B638719256 8.624379869 9.347947449 1.496 down 0.0271 RRSL_04075 o c Hypothetical Protein638719257 9.907379869 10.57314745 1.438 down 0.138 RRSL_04076 o c Transcriptional regulator, GntR family / AMINOTRANSFERASE CLASS-I( EC:2.6.1.- )638719262 10.04617987 9.934422449 1.192 up 0.481 RRSL_04081 o c Hypothetical Protein638719263 11.44717987 12.10944745 1.434 down 0.00432 RRSL_04082 o c Hypothetical Protein638719264 9.390954869 8.886372449 1.565 up 0.25 RRSL_04083 o c Hypothetical Protein638719265 10.63370487 9.983897449 1.73 up 0.0269 RRSL_04084 o c sensory transduction protein638719266 11.17345487 10.96452245 1.275 up 0.125 RRSL_04085 o c Hypothetical Protein638719267 9.526829869 10.23612245 1.482 down 0.131 RRSL_04086 o c Transcriptional regulator, MarR family638719269 8.341554869 9.190422449 1.632 down 0.0488 RRSL_04087 o c Glutamyl-tRNA(Gln) amidotransferase subunit A( EC:6.3.5.- )638719270 8.517779869 8.527247449 1.095 up 0.425 RRSL_04089 o c Sensor protein( EC:2.7.3.- )638719273 8.941854869 8.613472449 1.385 up 0.0298 RRSL_04092 o c Hypothetical Protein638719274 14.18570487 13.85424745 1.388 up 0.0022 RRSL_04093 o c Hypothetical Protein638719276 9.240979869 9.252572449 1.094 up 0.332 RRSL_04095 o c D-alanyl-meso-diaminopimelate endopeptidase( EC:3.4.- )638719280 9.306379869 9.522197449 1.052 down 0.841 RRSL_04099 o c Hypothetical Protein638719281 9.759379869 10.71697245 1.76 down 0.0641 RRSL_04100 o c SUA5 protein638719282 10.00335487 11.18607245 2.057 down 0.053 RRSL_04101 o c Phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit( EC:4.1.1.21 )638719283 10.61590487 11.75069745 1.99 down 0.0262 RRSL_04102 o c Phosphoribosylaminoimidazole carboxylase carboxyltransferase subunit( EC:4.1.1.21 )638719284 10.70622987 11.84467245 1.995 down 0.0318 RRSL_04103 o c Hypothetical Protein638719288 9.975429869 9.525247449 1.507 up 0.148 RRSL_04107 o c rarD RarD638719289 8.796779869 8.833797449 1.075 up 0.803 RRSL_04108 o c Hypothetical Protein638719290 10.93572987 11.20072245 1.089 down 0.464 RRSL_04109 o c Hypothetical Protein638719292 13.05970487 13.81329745 1.528 down 0.00408 RRSL_04111 o c Hypothetical protein638719294 10.66780487 11.78552245 1.967 down 0.0209 RRSL_04113 o c Hypothetical Protein638719295 9.378254869 10.27712245 1.69 down 0.0287 RRSL_04114 o c Alpha/beta hydrolase638719296 9.089629869 10.03159745 1.741 down 0.0413 RRSL_04115 o c Hypothetical Protein638719297 7.748104869 8.283197449 1.313 down 0.119 RRSL_04116 o c Zinc metalloprotease( EC:3.4.24.- )638719298 11.34872987 11.87082245 1.301 down 0.0884 RRSL_04117 o c Molybdenum cofactor biosynthesis protein C638719299 13.21222987 13.34454745 1.006 up 0.978 RRSL_04118 o c Hypothetical Protein638719300 16.09025487 16.29052245 1.041 down 0.749 RRSL_04119 o c pilA PilA638719301 11.35387987 11.40962245 1.061 up 0.732 RRSL_04120 o c plpA PlpA638719302 12.25212987 11.95302245 1.357 up 0.0276 RRSL_04121 o c Integral membrane protein638719303 13.42010487 14.13557245 1.488 down 0.174 RRSL_04122 o c Succinyl-CoA synthetase alpha chain( EC:6.2.1.5 )638719304 13.62210487 14.17742245 1.332 down 0.152 RRSL_04123 o c Succinyl-CoA synthetase beta chain( EC:6.2.1.5 )638719305 12.40935487 12.58812245 1.026 down 0.814 RRSL_04124 o c Hypothetical Protein638719306 11.54430487 12.75364745 2.096 down 0.0517 RRSL_04126 o c RecA protein638719307 8.727629869 8.715697449 1.112 up 0.325 RRSL_04127 o c Sensor protein qseC( EC:2.7.3.- )638719312 9.009379869 9.643172449 1.406 down 0.0264 RRSL_04131 o c 2-Octaprenyl-6-metoxyphenol hydroxylase and related FAD-dependent oxidoreductases638719313 9.151129869 8.737997449 1.468 up 0.18 RRSL_04133 o c Transcriptional regulatory protein638719314 8.744929869 9.266622449 1.301 down 0.0541 RRSL_04135 o c Transcriptional regulators, LysR family638719315 8.694704869 8.300397449 1.449 up 0.111 RRSL_04136 o c Pirin638719316 8.950004869 9.210072449 1.085 down 0.774 RRSL_04137 o c Serine protease( EC:3.4.21.- )638719317 11.42590487 11.67774745 1.079 down 0.833 RRSL_04138 o c ATP-dependent RNA helicase RhlE638719318 8.763979869 8.453047449 1.368 up 0.151 RRSL_04139 o c Transcriptional regulator, TetR family

638719319 9.189229869 8.504422449 1.773 up 0.0952 RRSL_04140 o c Acyl-CoA dehydrogenase( EC:1.3.99.- )638719320 8.437104869 8.330822449 1.187 up 0.251 RRSL_04141 o c 3-oxoacyl-[acyl-carrier protein] reductase( EC:1.1.1.100 )638719327 12.03407987 12.33347245 1.115 down 0.184 RRSL_04150 o c COG0621, tRNA 2-methylthioadenosine synthase638719328 12.20222987 12.65769745 1.242 down 0.0564 RRSL_04151 o c PhoH-like protein638719329 12.36860487 12.94874745 1.355 down 0.128 RRSL_04152 o c Hypothetical Metal-Binding Protein638719331 13.07302987 12.22077245 1.991 up 0.000932 RRSL_04155 o c corC CorC638719333 12.39357987 13.31494745 1.716 down 0.00337 RRSL_04157 o c Glycyl-tRNA synthetase alpha chain( EC:6.1.1.14 )638719336 9.898604869 10.99179745 1.933 down 0.0278 RRSL_04160 o c Phosphatase family protein638719337 11.40182987 11.34287245 1.149 up 0.152 RRSL_04161 o c N-acylhomoserine lactone synthase( EC:2.3.1.- )638719340 10.21185487 10.02162245 1.258 up 0.409 RRSL_04164 o c Sensory transduction protein kinase( EC:2.7.3.- )638719341 9.438754869 9.823947449 1.183 down 0.163 RRSL_04165 o c Two-component response regulator638719345 9.894754869 9.660497449 1.297 up 0.356 RRSL_04170 o c ABC transporter substrate-binding protein638719346 8.008479869 7.856397449 1.225 up 0.0617 RRSL_04171 o c Transcriptional regulatory protein638719348 7.504004869 7.455047449 1.141 up 0.435 RRSL_04173 o c Type I restriction-modification system restriction subunit( EC:3.1.21.3 )638719350 9.773454869 8.834522449 2.114 up 0.0821 RRSL_04175 o c Type I restriction-modification system methylation subunit638719351 10.68700487 9.964047449 1.82 up 0.0088 RRSL_04176 o c AAU3 protein precursor638719356 9.821229869 10.01444745 1.036 down 0.854 RRSL_04182 o c Shikimate kinase( EC:2.7.1.71 )638719357 10.87022987 10.86547245 1.106 up 0.749 RRSL_04183 o c Hypothetical Protein638719358 8.037129869 9.083322449 1.871 down 0.00986 RRSL_04184 o c Two component system histidine kinase( EC:2.7.3.- )638719361 10.79152987 11.45582245 1.436 down 0.0105 RRSL_04187 o c hydrolase-related protein638719362 8.118704869 8.821347449 1.475 down 0.0401 RRSL_04188 o c Oxidoreductase( EC:1.- )638719363 9.039554869 9.675072449 1.408 down 0.0397 RRSL_04189 o c Hypothetical Protein638719364 9.160954869 9.870572449 1.482 down 0.0822 RRSL_04190 o c Hypothetical Protein638719365 11.28952987 11.18499745 1.186 up 0.562 RRSL_04191 o c Periplasmic amino acid binding proteins638719366 7.686954869 8.461572449 1.55 down 0.00123 RRSL_04192 o c Transcriptional regulator, IclR family638719374 8.943154869 8.960097449 1.09 up 0.482 RRSL_04201 o c Hypothetical Protein638719375 11.55845487 10.46109745 2.36 up 0.068 RRSL_04202 o c Endonuclease( EC:3.1.30.- )638719376 10.98562987 10.94377245 1.135 up 0.387 RRSL_04203 o c Phospho-2-dehydro-3-deoxyheptonate aldolase( EC:4.1.2.15 )638719378 11.14590487 11.33199745 1.031 down 0.846 RRSL_04204 o c putative transport system permease protein638719380 12.71492987 13.83372245 1.968 down 0.0197 RRSL_04206 o c Tol system periplasmic component YbgF638719385 12.32632987 13.37194745 1.871 down 0.0322 RRSL_04211 o c TolQ protein638719386 11.34162987 11.67972245 1.145 down 0.0734 RRSL_04212 o c Short chain acyl-CoA thioesterase YbgC638719388 10.78222987 11.82034745 1.861 down 0.00306 RRSL_04215 o c Putative regulatory protein638719389 12.17552987 12.32222245 1.003 down 0.988 RRSL_04216 o c putative type-4 fimbrial biogenesis PilV-related transmembrane protein638719390 11.74672987 12.04042245 1.111 down 0.191 RRSL_04217 o c Type IV fimbrial biogenesis protein638719391 11.27172987 11.96024745 1.46 down 0.0123 RRSL_04218 o c Probably transmembrane protein638719392 10.92225487 11.49779745 1.35 down 0.0732 RRSL_04219 o c PILI ASSEMBLY PROTEIN, PILY1-related protein638719393 10.47620487 10.95862245 1.266 down 0.0342 RRSL_04220 o c probable type-4 fimbrial pilin-related transmembrane protein638719394 11.39457987 11.77962245 1.183 down 0.0541 RRSL_04221 o c putative type 4 fimbrial pilin related transmembrane protein638719395 7.357154869 7.713797449 1.16 down 0.363 RRSL_04222 o c Probable transmembrane protein638719396 8.554679869 7.954247449 1.672 up 0.214 RRSL_04223 o c Probably transmembrane protein638719397 8.574179869 8.045347449 1.591 up 0.289 RRSL_04223_5 o c type 4 fimbrial biogenesis pilx-related protein638719398 7.266979869 7.532472449 1.089 down 0.738 RRSL_04224 o c TYPE 4 FIMBRIAL BIOGENESIS, PilY1-related protein638719399 7.548504869 7.597322449 1.066 up 0.741 RRSL_04225 o c putative type-4 frimbrial pilin-related signal peptide protein638719400 8.833254869 8.451972449 1.436 up 0.35 RRSL_04226 o c putative type 4 fimbrial pilin related transmembrane protein

638719401 11.93982987 12.32139745 1.18 down 0.248 RRSL_04227 o cDiaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase( EC:1.1.1.193,EC:3.5.4.26 )

638719403 12.74487987 13.67397245 1.725 down 0.0132 RRSL_04230 o c 6,7-dimethyl-8-ribityllumazine synthase( EC:2.5.1.9 )638719406 11.56520487 12.23087245 1.437 down 0.27 RRSL_04233 o c Protein P7638719407 10.85337987 11.05542245 1.042 down 0.69 RRSL_04234 o c 3-polyprenyl-4-hydroxybenzoate decarboxylase( EC:4.1.1.- )638719409 7.818254869 8.369197449 1.327 down 0.0216 RRSL_04236 o c Hypothetical Protein638719410 11.80420487 12.08497245 1.101 down 0.244 RRSL_04237 o c Hypothetical Protein638719411 11.72782987 11.53774745 1.258 up 0.00594 RRSL_04238 o c Hypothetical Protein638719415 8.395904869 9.001422449 1.379 down 0.0204 RRSL_04241 o c NADPH dehydrogenase( EC:1.6.99.1 )638719416 13.79652987 13.89384745 1.031 up 0.85 RRSL_04242 o c Bacitracin resistance protein (Putative undecaprenol kinase)( EC:2.7.1.66 )638719417 8.639404869 9.197147449 1.334 down 0.108 RRSL_04243 o c Hypothetical Protein638719419 10.73430487 11.04214745 1.122 down 0.522 RRSL_04245 o c Transcriptional regulator, TetR family

638719424 9.400179869 9.507672449 1.023 up 0.851 RRSL_04250 o c 3-deoxy-D-manno-octulosonic-acid transferase( EC:2.- )638719425 9.148654869 10.27424745 1.977 down 0.033 RRSL_04251 o c Lipopolysaccharide heptosyltransferase-1( EC:2.- )638719426 11.76112987 12.72809745 1.771 down 0.0289 RRSL_04252 o c Hypothetical Protein638719427 12.46735487 13.03414745 1.342 down 0.0133 RRSL_04253 o c Hypothetical Protein638719428 10.93100487 11.78207245 1.635 down 0.0492 RRSL_04254 o c Putative undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase( EC:2.4.1.- )638719429 11.71487987 12.57587245 1.646 down 0.0149 RRSL_04255 o c Glycosyltransferase( EC:2.4.1.- )638719430 11.09362987 11.83637245 1.516 down 0.0582 RRSL_04256 o c dTDP-rhamnosyl transferase rfbF( EC:2.- )638719431 12.30865487 12.72192245 1.207 down 0.343 RRSL_04257 o c Oligosaccharide translocase (flippase)638719432 12.21725487 12.71134745 1.276 down 0.269 RRSL_04258 o c dTDP-4-dehydrorhamnose 3,5-epimerase( EC:5.1.3.13 )638719433 12.35500487 13.12104745 1.541 down 0.0988 RRSL_04259 o c Glucose-1-phosphate thymidylyltransferase( EC:2.7.7.24 )638719435 13.28865487 14.06359745 1.551 down 0.113 RRSL_04261 o c dTDP-glucose 4,6-dehydratase( EC:4.2.1.46 )638719436 10.70565487 10.85834745 1.007 down 0.931 RRSL_04262 o c Bis(5'-nucleosyl)-tetraphosphatase, symmetrical( EC:3.6.1.41 )638719437 11.56115487 11.97734745 1.209 down 0.108 RRSL_04263 o c 1-acyl-sn-glycerol-3-phosphate acyltransferase( EC:2.3.1.51 )638719438 10.70150487 11.52742245 1.606 down 0.0863 RRSL_04264 o c Aspartate carbamoyltransferase non-catalytic chain( EC:2.1.3.2 )638719439 10.89747987 11.49279745 1.369 down 0.0646 RRSL_04265 o c Aspartate carbamoyltransferase( EC:2.1.3.2 )638719440 12.36812987 12.63227245 1.088 down 0.543 RRSL_04266 o c pyrR PyrR( EC:2.4.2.9 )638719441 12.86365487 13.17024745 1.121 down 0.562 RRSL_04267 o c Transcriptional regulator, algH638719442 10.68920487 11.55877245 1.656 down 0.00422 RRSL_04269 o c Ribosomal small subunit pseudouridine synthase A( EC:4.2.1.70 )

638719444 10.78682987 11.52507245 1.512 down 0.0807 RRSL_04270 o cTranscription regulator composite two component regulatory protein (sensor histidine kinase and response regulator hybrid)

638719445 12.89515487 13.82442245 1.726 down 0.0142 RRSL_04271 o c pilJ PilJ638719446 11.63070487 12.27559745 1.417 down 0.229 RRSL_04272 o c pilI PilI638719447 12.87055487 13.65844745 1.565 down 0.0486 RRSL_04273 o c pilH PilH638719448 13.56602987 13.95002245 1.182 down 0.302 RRSL_04274 o c pilG PilG638719449 13.54452987 13.91742245 1.173 down 0.0972 RRSL_04275 o c Rubredoxin638719451 7.632029869 8.098572449 1.252 down 0.0293 RRSL_03826 o c Solute: Na+ symporter permease638719456 9.000004869 9.801797449 1.58 down 0.00317 RRSL_03831 o c Mechanosensitive ion channel638719460 12.15762987 12.03962245 1.197 up 0.0325 RRSL_03835 o c Hypothetical Protein638719461 9.577104869 10.32502245 1.522 down 0.0353 RRSL_03836 o c composite two-component regulatory protein (sensor kinase and response regulator hybrid)638719464 10.75942987 11.67929745 1.714 down 0.0353 RRSL_03839 o c Lipoprotein signal peptidase( EC:3.4.23.36 )

638719465 12.50860487 12.36682245 1.217 up 0.61 RRSL_03840 o cphosphopantothenate--cysteine ligase / phosphopantothenoylcysteine decarboxylase( EC:4.1.1.36,EC:6.3.2.5 )

638719466 10.44340487 10.97842245 1.313 down 0.00147 RRSL_03842 o c Luciferase-like monooxygenase( EC:1.14.- )638719467 10.51605487 11.54677245 1.851 down 0.027 RRSL_03843 o c Deoxyuridine 5'-triphosphate nucleotidohydrolase( EC:3.6.1.23 )638719468 12.56850487 12.78119745 1.05 down 0.832 RRSL_03844 o c Hypothetical Protein638719469 13.93060487 13.68629745 1.306 up 0.113 RRSL_03845 o c ATP-dependent Clp protease adaptor protein ClpS638719471 9.824779869 9.507897449 1.374 up 0.511 RRSL_03847 o c Hypothetical Protein638719472 10.15027987 9.459597449 1.78 up 0.187 RRSL_03849 o c Hypothetical Protein638719479 8.002904869 8.014547449 1.094 up 0.603 RRSL_03857 o c Transcriptional regulator, LysR family638719480 8.887679869 9.222122449 1.142 down 0.113 RRSL_03858 o c tungstate-binding protein precursor638719481 9.781004869 10.44407245 1.435 down 0.135 RRSL_03859 o c Hypothetical transcriptional regulatory protein638719483 8.292179869 8.294672449 1.101 up 0.51 RRSL_03861 o c Oxidoreductase( EC:1.1.1.- )638719484 10.45707987 10.58049745 1.012 up 0.932 RRSL_03862 o c Globin Family Protein638719485 9.955479869 10.58112245 1.398 down 0.0646 RRSL_03863 o c Hypothetical protein638719487 9.848904869 10.50557245 1.428 down 0.202 RRSL_03866 o c Lysine decarboxylase family638719488 8.347829869 7.943947449 1.459 up 0.184 RRSL_03868 o c Lipopolysaccharide N-acetylglucosaminyltransferase638719490 7.557129869 7.570347449 1.093 up 0.544 RRSL_03870 o c Lipase( EC:3.1.1.3 )638719491 11.33402987 11.29697245 1.131 up 0.247 RRSL_03871 o c Hypothetical Protein638719492 11.38217987 12.10874745 1.499 down 0.0324 RRSL_03872 o c Hypothetical Protein638719493 10.37085487 11.18929745 1.598 down 0.039 RRSL_03873 o c Hypothetical Protein638719494 11.45157987 12.23237245 1.557 down 0.0351 RRSL_03874 o c Specialized sigma subunits of RNA polymerase638719495 12.40810487 13.05187245 1.416 down 0.252 RRSL_03875 o c Acetolactate synthase large subunit( EC:2.2.1.6 )638719496 12.28692987 13.05647245 1.545 down 0.111 RRSL_03876 o c Acetolactate synthase small subunit( EC:2.2.1.6 )638719497 13.03535487 13.68369745 1.42 down 0.153 RRSL_03877 o c Ketol-acid reductoisomerase / 2-dehydropantoate 2-reductase( EC:1.1.1.169,EC:1.1.1.86 )638719501 9.908279869 10.64282245 1.508 down 0.0511 RRSL_03881 o c Hypothetical Protein638719502 9.765854869 10.49932245 1.507 down 0.045 RRSL_03882 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638719503 15.95920487 16.18082245 1.056 down 0.505 RRSL_03884 o c SSU ribosomal protein S15P

638719504 14.25257987 14.82619745 1.349 down 0.243 RRSL_03885 o c Polyribonucleotide nucleotidyltransferase( EC:2.7.7.8 )638719505 10.59662987 11.40672245 1.589 down 0.0574 RRSL_03886 o c Hypothetical protein638719506 10.39002987 10.84417245 1.241 down 0.263 RRSL_03887 o c Hypothetical Protein638719510 14.38940487 14.80309745 1.207 down 0.143 RRSL_03890 o c NADH-quinone oxidoreductase chain A( EC:1.6.5.3 )638719511 13.37535487 14.17457245 1.577 down 0.0879 RRSL_03891 o c NADH-quinone oxidoreductase chain B( EC:1.6.5.3 )638719513 12.06660487 13.22269745 2.02 down 0.0592 RRSL_03893 o c Hypothetical Protein( EC:1.6.99.3 )638719514 13.66637987 14.51834745 1.636 down 0.0196 RRSL_03894 o c NADH-quinone oxidoreductase chain E( EC:1.6.5.3 )638719515 11.99155487 13.20504745 2.102 down 0.0539 RRSL_03895 o c NADH-quinone oxidoreductase chain F( EC:1.6.5.3,EC:1.6.99.5 )638719517 14.09372987 14.75422245 1.432 down 0.0777 RRSL_03897 o c NADH-quinone oxidoreductase chain H( EC:1.6.5.3 )638719518 12.71285487 13.46919745 1.531 down 0.0909 RRSL_03898 o c NADH-quinone oxidoreductase chain I( EC:1.6.5.3,EC:1.6.99.3 )638719519 12.32252987 13.32127245 1.811 down 0.0139 RRSL_03899 o c NADH-quinone oxidoreductase chain J( EC:1.6.5.3 )638719520 14.02727987 14.41459745 1.185 down 0.304 RRSL_03900 o c NADH-quinone oxidoreductase chain K( EC:1.6.5.3 )638719522 13.56972987 14.22224745 1.424 down 0.0603 RRSL_03902 o c NADH-quinone oxidoreductase chain M( EC:1.6.5.3 )638719524 11.62940487 12.75852245 1.982 down 0.0239 RRSL_03904 o c Hypothetical protein638719525 10.93787987 11.43732245 1.281 down 0.0137 RRSL_03905 o c Phosphohydrolase (MutT/nudix family protein)638719527 8.744729869 8.666447449 1.164 up 0.43 RRSL_03907 o c Acyl-CoA dehydrogenase( EC:1.3.99.- )638719528 8.443529869 8.361347449 1.167 up 0.293 RRSL_03908 o c Acyl-CoA dehydrogenase, short-chain specific( EC:1.3.99.2 )638719532 9.780704869 8.913872449 2.011 up 0.067 RRSL_03912 o c amide-urea transport system permease protein638719534 8.406254869 8.779672449 1.174 down 0.135 RRSL_03914 o c amide-urea transport atp-binding protein638719535 8.903104869 9.042047449 1.001 up 0.989 RRSL_03915 o c amide-urea transport atp-binding protein638719577 11.49790487 12.04919745 1.328 down 0.0259 RRSL_03958 o c hypothetical protein638719578 7.558329869 7.339972449 1.283 up 0.183 RRSL_03959 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638719579 11.87932987 11.69852245 1.25 up 0.166 RRSL_03960 o c hypothetical protein638719580 10.15820487 11.36327245 2.089 down 0.0727 RRSL_03961 o c hypothetical protein638719581 11.84477987 11.40512245 1.496 up 0.0783 RRSL_03962 o c Transcriptional regulatory protein638719582 8.595379869 8.451672449 1.218 up 0.702 RRSL_03963 o c Bacitracin transport permease protein bcrC homolog638719589 11.32172987 11.65159745 1.139 down 0.645 RRSL_03971 o c hypothetical protein638719590 10.29950487 9.661947449 1.716 up 0.0924 RRSL_03972 o c Permease638719591 6.397779869 7.232072449 1.616 down 0.0275 RRSL_03973 o c Phosphinothricin N-acetyltransferase( EC:2.3.1.- )638719592 10.55417987 10.17667245 1.433 up 0.286 RRSL_03974 o c hypothetical protein638719593 9.290704869 8.363322449 2.098 up 0.0601 RRSL_03975 o c D-lactate dehydrogenase( EC:1.1.1.28 )638719595 8.617104869 8.411197449 1.272 up 0.118 RRSL_03977 o c Acetoin catabolism regulatory protein638719596 10.40477987 10.32047245 1.169 up 0.37 RRSL_03978 o c Aldehyde dehydrogenase( EC:1.2.1.3 )638719597 9.889029869 9.516447449 1.428 up 0.042 RRSL_03979 o c Ethanolamine ammonia-lyase heavy chain( EC:4.3.1.7 )638719598 7.447954869 7.994797449 1.324 down 0.0958 RRSL_03980 o c Ethanolamine ammonia-lyase light chain( EC:4.3.1.7 )638719599 9.613379869 9.962897449 1.154 down 0.255 RRSL_03981 o c Exodeoxyribonuclease I( EC:3.1.11.1 )638719602 8.052729869 8.625622449 1.348 down 0.172 RRSL_03984 o c Transcriptional regulator, GntR family / AMINOTRANSFERASE CLASS-I( EC:2.6.1.- )638719609 11.74705487 12.69419745 1.747 down 0.0146 RRSL_03991 o c gspD GspD638719610 9.761404869 9.948572449 1.032 down 0.816 RRSL_03992 o c gspN GspN638719611 11.46187987 11.87057245 1.203 down 0.434 RRSL_03993 o c gspM GspM638719613 11.90825487 11.85499745 1.144 up 0.211 RRSL_03995 o c gspK GspK638719614 10.44080487 11.15492245 1.487 down 0.0404 RRSL_03996 o c gspJ GspJ638719616 12.88107987 13.64392245 1.538 down 0.0299 RRSL_03998 o c gspH GspH638719618 10.26217987 10.58652245 1.134 down 0.329 RRSL_04000 o c gspC GspC638719621 10.18732987 10.45432245 1.09 down 0.611 RRSL_04003 o c Transcriptional regulator, AsnC family638719623 9.553179869 9.144572449 1.464 up 0.0671 RRSL_04005 o c hypothetical protein638719625 10.99035487 10.49367245 1.556 up 0.168 RRSL_04007 o c Acetyltransferase( EC:2.3.1.- )638719626 9.709079869 9.694722449 1.114 up 0.381 RRSL_04008 o c kefC KefC638719651 10.72285487 10.85219745 1.008 up 0.98 RRSL_04034 o c Acetyl-CoA acetyltransferase( EC:2.3.1.9 )638719652 8.668229869 9.306122449 1.41 down 0.392 RRSL_04035 o c Short chain dehydrogenase638719653 7.749004869 7.961022449 1.049 down 0.854 RRSL_04037 o c Acyl-CoA dehydrogenase, short-chain specific( EC:1.3.99.2 )638719654 9.042404869 9.336747449 1.111 down 0.63 RRSL_04038 o c 2-hydroxychromene-2-carboxylate isomerase( EC:5.3.99.- )638719655 8.512954869 9.363472449 1.634 down 0.0609 RRSL_04040 o c hypothetical protein638719656 9.268754869 9.643022449 1.174 down 0.511 RRSL_04041 o c Methylcrotonyl-CoA carboxylase carboxyl transferase subunit( EC:6.4.1.4 )638719657 8.913904869 9.594697449 1.453 down 0.0375 RRSL_04042 o c Acylamino-acid-releasing enzyme( EC:3.4.19.1 )

638719659 11.94585487 11.86064745 1.17 up 0.363 RRSL_03441 o cGTP pyrophosphokinase / Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase( EC:2.7.6.5,EC:3.1.7.2 )

638719660 12.98725487 13.76817245 1.557 down 0.0486 RRSL_03442 o c DNA-directed RNA polymerase omega chain( EC:2.7.7.6 )638719661 10.71175487 11.64819745 1.734 down 0.0303 RRSL_03443 o c Guanylate kinase( EC:2.7.4.8 )638719663 13.13645487 13.20842245 1.049 up 0.586 RRSL_03444 o c Cell cycle protein kinase CDC5/MSD2( EC:2.7.1.- )638719664 10.38315487 10.82622245 1.232 down 0.272 RRSL_03446 o c Protein phosphatase 2C( EC:3.1.3.16 )638719666 9.561379869 10.59149745 1.851 down 0.00634 RRSL_03448 o c Xanthosine triphosphate pyrophosphatase( EC:3.6.1.- )638719667 10.38060487 10.46524745 1.04 up 0.801 RRSL_03449 o c Coproporphyrinogen oxidase, anaerobic( EC:1.- )638719670 7.738554869 8.450347449 1.484 down 0.0195 RRSL_03451 o c Pyrrolidone-carboxylate peptidase( EC:3.4.19.3 )638719671 8.875129869 9.595797449 1.493 down 0.0691 RRSL_03452 o c C4-dicarboxylate-binding protein638719674 9.408179869 10.30447245 1.687 down 0.0676 RRSL_03455 o c Lactam utilization protein LAMB638719677 8.059754869 7.593572449 1.524 up 0.155 RRSL_03459 o c Transmembrane drug transport protein, MFS family638719678 9.716554869 10.18249745 1.252 down 0.105 RRSL_03460 o c Nucleoside transport ATP-binding protein638719679 8.728479869 8.988047449 1.085 down 0.362 RRSL_03461 o c Nucleoside transport system permease protein638719680 9.072204869 9.649122449 1.352 down 0.0919 RRSL_03462 o c Nucleoside transport system permease protein638719681 12.48097987 13.06674745 1.36 down 0.00303 RRSL_03463 o c Nucleoside-binding protein638719686 10.27962987 10.76099745 1.265 down 0.0165 RRSL_03469 o c Hypothetical Protein638719687 11.02810487 12.07212245 1.869 down 0.0429 RRSL_03470 o c Quinone oxidoreductase( EC:1.6.5.5 )638719688 10.54720487 11.65979745 1.96 down 0.00206 RRSL_03471 o c Methylglyoxal synthase( EC:4.2.3.3 )638719690 9.747679869 9.685447449 1.151 up 0.708 RRSL_03473 o c Transporter, drug/metabolite exporter family638719691 9.085154869 9.646997449 1.338 down 0.0303 RRSL_03474 o c Uracil phosphoribosyltransferase( EC:2.4.2.9 )638719692 9.346354869 10.42824745 1.918 down 0.0031 RRSL_03475 o c ATPase638719693 11.86675487 12.31894745 1.24 down 0.152 RRSL_03476 o c Hypothetical cytosolic protein638719694 11.29010487 11.79439745 1.285 down 0.273 RRSL_03477 o c Phosphoribosylamine--glycine ligase( EC:6.3.4.13 )638719695 9.805904869 10.68529745 1.667 down 0.038 RRSL_03478 o c Coproporphyrinogen III oxidase( EC:1.3.3.3 )638719696 10.78085487 11.72389745 1.742 down 0.00985 RRSL_03479 o c COG 1057, nicotinic acid mononucleotide adenylyltransferase638719697 15.06062987 15.02104745 1.133 up 0.236 RRSL_03480 o c iojap protein family638719698 10.94640487 11.49389745 1.324 down 0.0113 RRSL_03481 o c Hypothetical cytosolic protein638719699 9.191004869 9.250672449 1.058 up 0.747 RRSL_03482 o c Septum formation protein Maf638719700 11.64100487 11.63894745 1.104 up 0.194 RRSL_03483 o c Ribonuclease G( EC:3.1.4.- )638719701 8.614829869 8.233497449 1.436 up 0.0482 RRSL_03484 o c Hypothetical Protein638719702 10.11722987 9.702847449 1.47 up 0.0577 RRSL_03485 o c Hypothetical protein638719703 10.46170487 10.79744745 1.143 down 0.261 RRSL_03486 o c ABC-TYPE MULTIDRUG TRANSPORT SYSTEM. ATPase and permease components.638719704 10.26597987 10.81639745 1.327 down 0.0861 RRSL_03487 o c Hypothetical Protein638719705 8.773579869 9.450072449 1.448 down 0.0289 RRSL_03488 o c alpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase( EC:2.4.1.- )638719706 10.42332987 10.78757245 1.166 down 0.288 RRSL_03489 o c Hypothetical Protein638719707 10.45037987 10.70207245 1.079 down 0.536 RRSL_03490 o c Hypothetical Protein638719708 9.714529869 10.30097245 1.361 down 0.0586 RRSL_03491 o c DNA polymerase III alpha subunit( EC:2.7.7.7 )638719709 12.70682987 13.03729745 1.139 down 0.569 RRSL_03492 o c Rhodanese-related sulfurtransferases638719713 10.64872987 11.22307245 1.349 down 0.00657 RRSL_03497 o c tRNA synthetases class I, catalytic domain638719714 10.72257987 11.95357245 2.127 down 0.06 RRSL_03498 o c ATP-dependent RNA helicase638719716 10.51205487 10.71002245 1.039 down 0.757 RRSL_03500 o c Transcriptional regulator, TetR family638719717 9.924879869 9.920822449 1.106 up 0.731 RRSL_03501 o c Metal-dependent hydrolase( EC:3.- )638719721 10.40457987 11.13229745 1.501 down 0.00767 RRSL_03504 o c DNA primase( EC:2.7.7.- )638719723 11.16812987 9.776072449 2.895 up 0.103 RRSL_03506 o c NAD(FAD)-utilizing dehydrogenases638719724 8.952504869 9.829222449 1.664 down 0.00592 RRSL_03507 o c O-sialoglycoprotein endopeptidase( EC:3.4.24.57 )638719725 12.11167987 12.87662245 1.54 down 0.0056 RRSL_03509 o c Hypothetical cytosolic protein638719727 10.84370487 11.65904745 1.595 down 0.00365 RRSL_03510 o c 1-deoxy-D-xylulose 5-phosphate synthase( EC:2.2.1.7,EC:4.1.3.37 )

638719728 9.684104869 10.74069745 1.885 down 0.0215 RRSL_03511 o cDimethylallyltransferase / Geranyltranstransferase / Geranylgeranyl pyrophosphate synthetase( EC:2.5.1.1,EC:2.5.1.10,EC:2.5.1.29 )

638719730 11.99010487 12.42792245 1.227 down 0.0863 RRSL_03513 o c AlcE638719731 9.368604869 9.922797449 1.33 down 0.0139 RRSL_03514 o c Transporter, drug/metabolite exporter family638719732 10.25242987 11.11529745 1.648 down 0.00552 RRSL_03515 o c Thiosulfate sulfurtransferase( EC:2.8.1.1 )638719733 11.16645487 10.89894745 1.327 up 0.377 RRSL_03516 o c Histidine-rich protein Ke4638719734 11.29485487 12.12777245 1.614 down 0.0116 RRSL_03518 o c NADH dehydrogenase( EC:1.6.99.3 )638719735 9.866379869 10.95577245 1.928 down 0.0207 RRSL_03520 o c DNA polymerase I( EC:2.7.7.7 )638719736 12.87682987 13.25817245 1.18 down 0.383 RRSL_03519 o c 3-isopropylmalate dehydrogenase( EC:1.1.1.85 )638719737 13.67915487 14.04104745 1.164 down 0.145 RRSL_03521 o c Hypothetical Protein638719738 10.42100487 11.37234745 1.752 down 0.00343 RRSL_03522 o c Homoserine kinase( EC:2.7.1.39 )

638719739 12.13890487 12.37799745 1.069 down 0.485 RRSL_03523 o c Hypothetical Protein638719740 11.13970487 12.03032245 1.68 down 0.0793 RRSL_03524 o c Valyl-tRNA synthetase( EC:6.1.1.9 )638719741 10.31627987 11.08724745 1.546 down 0.108 RRSL_03526 o c UTP--glucose-1-phosphate uridylyltransferase( EC:2.7.7.9 )638719743 13.32657987 13.52944745 1.043 down 0.854 RRSL_03528 o c Bacterial Protein Translation Initiation Factor 1 (IF-1)638719745 13.12520487 12.37559745 1.854 up 0.0137 RRSL_03530 o c Hypothetical Protein638719747 11.89802987 12.79029745 1.682 down 0.034 RRSL_03532 o c Hypothetical Protein638719749 9.005079869 7.672972449 2.777 up 0.191 RRSL_03534 o c Transcriptional regulators, LysR family638719751 8.721329869 9.476222449 1.529 down 0.0199 RRSL_03536 o c livF LivF638719752 8.522929869 8.936147449 1.207 down 0.489 RRSL_03537 o c livG LivG638719753 10.02865487 9.573222449 1.512 up 0.387 RRSL_03538 o c livM LivM638719754 9.427004869 9.626947449 1.041 down 0.904 RRSL_03539 o c livH LivH638719755 7.987204869 8.521897449 1.313 down 0.194 RRSL_03540 o c 4-carboxymuconolactone decarboxylase( EC:4.1.1.44 )638719756 8.794354869 9.221072449 1.218 down 0.138 RRSL_03541 o c 3-oxoadipate enol-lactonase( EC:3.1.1.24 )638719757 7.102479869 7.918097449 1.595 down 0.168 RRSL_03542 o c 3-carboxy-cis,cis-muconate cycloisomerase( EC:5.5.1.2 )638719758 8.222154869 9.345297449 1.974 down 0.00463 RRSL_03543 o c 3-ketoacyl-CoA thiolase( EC:2.3.1.16,EC:2.3.1.9 )638719760 9.376454869 10.45099745 1.909 down 0.00886 RRSL_03545 o c 3-oxoadipate CoA-transferase subunit B( EC:2.8.3.6 )638719761 8.590779869 9.455747449 1.65 down 0.039 RRSL_03546 o c 3-oxoadipate CoA-transferase subunit A( EC:2.8.3.6 )638719762 10.23332987 9.869897449 1.419 up 0.375 RRSL_03547 o c Transcriptional regulator, IclR family638719763 10.97947987 11.46419745 1.268 down 0.0399 RRSL_03548 o c Hypothetical Protein638719764 10.23377987 10.66299745 1.22 down 0.32 RRSL_03550 o c Hypothetical Protein638719765 9.937554869 9.529597449 1.463 up 0.242 RRSL_03551 o c glnP GlnP638719766 8.932929869 8.619472449 1.37 up 0.416 RRSL_03552 o c Glutamine transport system permease protein glnP638719767 8.349754869 8.268322449 1.167 up 0.461 RRSL_03553 o c glnQ GlnQ638719769 13.59295487 14.04829745 1.242 down 0.249 RRSL_03728 o c 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase( EC:2.7.1.148 )638719770 10.31947987 11.30822245 1.798 down 0.0749 RRSL_03729 o c lolB LolB638719771 11.71095487 12.50872245 1.575 down 0.0388 RRSL_03730 o c Tetratricopeptide repeat family protein638719772 9.323154869 9.832922449 1.29 down 0.104 RRSL_03731 o c Formamidopyrimidine-DNA glycosylase( EC:3.2.2.23 )638719774 8.861554869 9.242547449 1.18 down 0.123 RRSL_03733 o c A/G-specific adenine DNA glycosylase( EC:3.2.2.- )638719775 11.01005487 11.62469745 1.387 down 0.0516 RRSL_03734 o c ATP-dependent protease La( EC:3.4.21.53 )638719776 12.03787987 12.51357245 1.26 down 0.0541 RRSL_03735 o c ATP-binding protein (contains P-loop)638719777 14.97377987 15.63497245 1.433 down 0.0897 RRSL_03736 o c hypothetical protein638719778 10.15397987 10.53227245 1.178 down 0.39 RRSL_03737 o c hpr(ser) kinase / phosphatase( EC:2.7.1.-,EC:3.1.3.- )638719779 13.04275487 13.18012245 1.003 up 0.98 RRSL_03738 o c Nitrogen regulatory IIA protein( EC:2.7.1.69 )638719780 16.77735487 16.21184745 1.632 up 0.000205 RRSL_03739 o c Ribosome-associated factor Y638719781 12.32810487 11.85444745 1.531 up 0.0205 RRSL_03740 o c rpoN RpoN638719782 10.89120487 11.44189745 1.327 down 0.0162 RRSL_03741 o c ABC transporter ATP-binding protein638719783 11.87915487 12.61569745 1.51 down 0.0119 RRSL_03742 o c Protein yhbN precursor638719784 11.41800487 11.44867245 1.079 up 0.297 RRSL_03743 o c hypothetical protein638719785 11.61142987 12.31732245 1.478 down 0.00616 RRSL_03744 o c 3-deoxy-manno-octulosonate-8-phosphatase( EC:3.1.3.45 )638719786 9.876704869 9.630347449 1.308 up 0.0735 RRSL_03745 o c transmembrane glutathione-regulated potassium-efflux system protein K+/H+ antiporter638719787 10.88067987 10.34962245 1.594 up 0.00985 RRSL_03747 o c protease I( EC:3.4.- )638719788 11.33742987 11.74789745 1.204 down 0.0113 RRSL_03748 o c Adenine phosphoribosyltransferase( EC:2.4.2.7 )638719789 11.03167987 11.47579745 1.233 down 0.099 RRSL_03750 o c hypothetical protein638719790 10.14277987 11.07454745 1.729 down 0.000272 RRSL_03752 o c Excinuclease ABC subunit A (DNA repair ATP-binding protein)638719791 10.02462987 10.48102245 1.243 down 0.029 RRSL_03752_1 o c transmembrane multidrug-efflux transporter MFS-family638719792 12.76135487 13.46199745 1.473 down 0.105 RRSL_03753 o c Single-strand DNA binding protein638719796 9.007729869 9.709547449 1.474 down 0.0283 RRSL_03758 o c hypothetical protein638719797 9.946354869 10.79714745 1.634 down 0.00576 RRSL_03759 o c 3-oxoacyl-[acyl-carrier-protein] synthase( EC:2.3.1.41 )638719798 8.354604869 8.974872449 1.393 down 0.0195 RRSL_03760 o c hypothetical protein638719800 9.657054869 9.130122449 1.589 up 0.202 RRSL_03762 o c hypothetical protein638719801 7.932954869 7.751722449 1.25 up 0.398 RRSL_03763 o c Dolichol-phosphate mannosyltransferase( EC:2.4.1.83 )638719802 9.448479869 9.099522449 1.405 up 0.0748 RRSL_03764 o c AMP-(fatty)acid ligases638719803 9.279504869 9.670222449 1.188 down 0.232 RRSL_03765 o c hypothetical protein638719805 11.44142987 11.82307245 1.18 down 0.293 RRSL_03767 o c Acyl carrier protein638719806 11.59295487 12.17184745 1.353 down 0.0308 RRSL_03768 o c 3-oxoacyl-[acyl-carrier protein] reductase( EC:1.1.1.100 )638719809 10.66665487 10.69387245 1.082 up 0.762 RRSL_03772 o c Esterase( EC:3.1.1.- )638719810 11.04785487 10.83567245 1.277 up 0.413 RRSL_03773 o c hypothetical protein

638719811 11.62345487 11.75287245 1.008 up 0.87 RRSL_03774 o c Gluconokinase( EC:2.7.1.12 )638719812 10.22670487 9.897172449 1.386 up 0.0786 RRSL_03775 o c Long-chain-fatty-acid--CoA ligase( EC:6.2.1.3 )638719815 8.194754869 8.053897449 1.216 up 0.611 RRSL_03778 o c Bacteriocin processing peptidase638719816 9.476904869 8.740172449 1.838 up 0.244 RRSL_03779 o c hypothetical protein638719817 9.650954869 9.510097449 1.216 up 0.281 RRSL_03780 o c Acetate kinase( EC:2.7.2.1 )638719818 11.10617987 11.54424745 1.228 down 0.447 RRSL_03781 o c Queuosine biosynthesis protein QueF638719821 10.62465487 10.54824745 1.163 up 0.555 RRSL_03785 o c Spore maturation protein A / Spore maturation protein B638719822 10.48280487 10.73892245 1.082 down 0.715 RRSL_03786 o c hypothetical protein638719823 10.00672987 11.02194745 1.832 down 0.0263 RRSL_03787 o c Anaerobic glycerol-3-phosphate dehydrogenase subunit C638719824 13.25495487 14.15814745 1.695 down 0.0598 RRSL_03789 o c ABC transporter ATP-binding protein638719826 11.28602987 12.27912245 1.804 down 0.0295 RRSL_03791 o c Ubiquinone/menaquinone biosynthesis methyltransferase ubiE( EC:2.1.1.- )638719828 9.776579869 10.09087245 1.127 down 0.291 RRSL_03793 o c hypothetical protein638719831 10.93050487 11.11617245 1.03 down 0.875 RRSL_03796 o c Sodium/pantothenate symporter638719833 12.08395487 12.66279745 1.353 down 0.00122 RRSL_03798 o c transmembrane protein638719835 12.93182987 13.67757245 1.519 down 0.0163 RRSL_03800 o c dATP pyrophosphohydrolase( EC:3.6.1.- )638719836 11.12172987 12.24372245 1.972 down 0.00481 RRSL_03801 o c dioxygenase( EC:1.13.11.- )638719837 10.52480487 10.99744745 1.257 down 0.0981 RRSL_03802 o c Cardiolipin synthetase( EC:2.7.8.- )638719838 9.466904869 9.941097449 1.259 down 0.25 RRSL_03803 o c Acetyl-CoA:acetoacetyl-CoA transferase alpha subunit( EC:2.8.3.- )638719839 11.94970487 12.69049745 1.514 down 0.105 RRSL_03804 o c Transcriptional regulator, TetR family638719840 12.72165487 13.56634745 1.627 down 0.0556 RRSL_03805 o c Acyl-CoA dehydrogenase( EC:1.3.99.3 )638719842 12.84870487 13.71982245 1.657 down 0.0702 RRSL_03807 o c 3-ketoacyl-CoA thiolase( EC:2.3.1.16 )638719843 10.72465487 11.93789745 2.101 down 0.0692 RRSL_03808 o c dbi-related protein 1638719844 10.08187987 10.12699745 1.069 up 0.719 RRSL_03809 o c Multidrug resistance ABC transporter ATP-binding and permease protein638719845 10.09042987 10.80124745 1.483 down 0.037 RRSL_03811 o c hypothetical protein638719851 11.51505487 11.89889745 1.182 down 0.0319 RRSL_03817 o c Glutamine amidotransferases class-II638719853 8.467654869 9.131922449 1.436 down 0.136 RRSL_03819 o c Glycerate dehydrogenase / Hydroxypyruvate reductase( EC:1.1.1.29,EC:1.1.1.81 )638719854 9.693779869 10.57924745 1.674 down 0.0376 RRSL_03820 o c Dihydroorotase( EC:3.5.2.3 )638719855 9.969329869 10.37922245 1.204 down 0.193 RRSL_03821 o c hypothetical protein638719856 10.62065487 11.14037245 1.299 down 0.117 RRSL_03823 o c OsmC-like protein638719860 9.302554869 9.682222449 1.179 down 0.369 RRSL_03558 o c AMP nucleosidase( EC:3.2.2.4 )638719867 14.51832987 14.64444745 1.01 up 0.911 RRSL_03565 o c Acyl-CoA desaturase( EC:1.14.19.1 )638719868 10.99132987 11.42442245 1.223 down 0.187 RRSL_03566 o c Quinolinate synthetase A( EC:4.1.99.- )638719869 9.610579869 10.38469745 1.55 down 0.093 RRSL_03567 o c Nicotinate-nucleotide pyrophosphorylase (carboxylating)( EC:2.4.2.19 )638719870 9.591879869 10.46244745 1.657 down 0.0445 RRSL_03568 o c L-aspartate oxidase( EC:1.4.3.16 )638719871 16.42025487 16.86477245 1.233 down 0.00395 RRSL_03569 o c LSU ribosomal protein L33P638719872 15.32295487 15.94712245 1.397 down 0.0155 RRSL_03570 o c LSU ribosomal protein L28P638719874 10.23750487 11.05779745 1.6 down 0.141 RRSL_03573 o c 4-hydroxy-3-methylbut-2-enyl diphosphate reductase( EC:1.17.1.2 )638719875 14.26290487 15.28559745 1.841 down 0.0269 RRSL_03574 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638719880 9.454929869 10.13719745 1.454 down 0.0515 RRSL_03579 o c Acetyltransferase( EC:2.3.1.- )638719881 12.01005487 12.87527245 1.651 down 0.00864 RRSL_03580 o c Acetylornithine aminotransferase( EC:2.6.1.11 )638719882 12.34525487 13.11709745 1.547 down 0.00316 RRSL_03582 o c Oxidoreductase638719883 9.582804869 10.59492245 1.828 down 0.0392 RRSL_03581 o c Nucleoside-diphosphate-sugar epimerases638719889 8.398029869 8.672472449 1.096 down 0.614 RRSL_03587 o c 2-hydroxy-3-oxopropionate reductase( EC:1.1.1.60 )638719891 12.34005487 12.27677245 1.152 up 0.0796 RRSL_03589 o c Cys regulon transcriptional activator638719893 11.67065487 10.81919745 1.99 up 0.0333 RRSL_03591 o c Sulfite reductase (Ferredoxin)( EC:1.8.7.1 )638719895 13.28250487 12.89377245 1.444 up 0.0166 RRSL_03593 o c Phosphoadenosine phosphosulfate reductase( EC:1.8.4.8 )638719896 11.84695487 11.84477245 1.104 up 0.689 RRSL_03594 o c Sulfate adenylyltransferase subunit 2( EC:2.7.7.4 )638719897 10.96427987 11.07272245 1.023 up 0.922 RRSL_03595 o c Sulfate adenylyltransferase subunit 1( EC:2.7.7.4 )638719898 10.98375487 10.87704745 1.187 up 0.429 RRSL_03596 o c Hypothetical Protein638719899 10.07892987 9.468822449 1.683 up 0.0229 RRSL_03597 o c 5-carboxymethyl-2-hydroxymuconate delta-isomerase( EC:5.3.3.10 )638719900 9.430779869 9.767872449 1.145 down 0.441 RRSL_03598 o c Hypothetical Protein638719901 10.50010487 10.77524745 1.096 down 0.278 RRSL_03599 o c Hypothetical membrane spanning protein638719902 13.09065487 13.35017245 1.085 down 0.551 RRSL_03600 o c Hypothetical membrane spanning protein638719904 13.35207987 14.17657245 1.605 down 0.000956 RRSL_03602 o c DNA polymerase III, chi subunit( EC:2.7.7.7 )638719905 9.842954869 10.72062245 1.665 down 0.0083 RRSL_03603 o c Hypothetical Protein638719906 10.80450487 11.75627245 1.753 down 0.00293 RRSL_03604 o c Dihydroxy-acid dehydratase( EC:4.2.1.9 )638719907 8.612529869 8.741922449 1.008 up 0.966 RRSL_03605 o c Transcriptional regulators, LysR family

638719908 11.66817987 12.30207245 1.406 down 0.0353 RRSL_03606 o c Prolipoprotein diacylglyceryl transferase( EC:2.4.99.- )638719910 11.83457987 11.85582245 1.087 up 0.575 RRSL_03608 o c Hypothetical protein638719911 13.37777987 14.08067245 1.475 down 0.0105 RRSL_03609 o c Hypothetical Protein638719912 10.56700487 10.83332245 1.09 down 0.687 RRSL_03610 o c Vitamin B12 receptor638719913 9.704904869 9.484022449 1.285 up 0.183 RRSL_03611 o c fecD FecD638719914 9.575704869 9.281872449 1.352 up 0.435 RRSL_03612 o c Hypothetical Protein638719915 12.39632987 12.26729745 1.206 up 0.507 RRSL_03613 o c Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase( EC:2.4.2.21 )638719916 9.483554869 9.750572449 1.09 down 0.41 RRSL_03614 o c Cobalamin [5'-phosphate] synthase( EC:2.- )638719917 9.647554869 9.546322449 1.183 up 0.319 RRSL_03615 o c Alpha-ribazole-5'-phosphate phosphatase( EC:3.1.3.- )638719918 7.901629869 8.475922449 1.349 down 0.208 RRSL_03617 o c CobC protein638719919 8.935604869 9.121497449 1.031 down 0.788 RRSL_03618 o c Hypothetical Protein638719920 10.06747987 10.65199745 1.359 down 0.0154 RRSL_03619 o c cobinamide kinase / cobinamide phosphate guanylyltransferase( EC:2.7.1.-,EC:2.7.7.- )638719921 10.06237987 10.51144745 1.237 down 0.109 RRSL_03620 o c Cobyric acid synthase( EC:3.- )638719922 9.300904869 9.369822449 1.051 up 0.584 RRSL_03621 o c Hypothetical Protein638719923 11.67077987 12.18544745 1.295 down 0.0214 RRSL_03622 o c Pantoate--beta-alanine ligase( EC:6.3.2.1 )638719924 12.06145487 12.98757245 1.722 down 0.0261 RRSL_03623 o c Segregation and condensation protein ScpA638719925 8.666529869 8.919647449 1.08 down 0.441 RRSL_03624 o c Outer membrane protein638719926 10.36450487 10.13459745 1.293 up 0.178 RRSL_03625 o c Hypothetical Outer Membrane Protein638719927 13.24565487 13.00754745 1.301 up 0.0034 RRSL_03626 o c Hypothetical Protein638719928 11.36195487 12.20239745 1.623 down 0.0778 RRSL_03627 o c Methionyl-tRNA synthetase / Protein secretion chaperonin CsaA( EC:6.1.1.10 )638719930 12.65575487 12.17717245 1.537 up 0.306 RRSL_03629 o c Iron-sulfur cluster assembly/repair protein ApbC638719931 9.268354869 8.682722449 1.655 up 0.147 RRSL_03631 o c Hypothetical Protein638719933 7.016204869 7.346497449 1.139 down 0.163 RRSL_03633 o c Hypothetical Protein638719942 11.48850487 12.15412245 1.437 down 0.00108 RRSL_03642 o c Deoxycytidine triphosphate deaminase( EC:3.5.4.13 )638719943 10.67565487 11.59339745 1.712 down 0.0523 RRSL_03643 o c Biodegradative arginine decarboxylase( EC:4.1.1.19 )638719945 10.32297987 9.745422449 1.646 up 0.0101 RRSL_03647 o c RNA polymerase sigma factor sigk638719951 12.36867987 13.51074745 2 down 0.0107 RRSL_00717 o c Protein translocase subunit secF638719955 12.74172987 13.79362245 1.879 down 0.00661 RRSL_00722 o c Adenylosuccinate lyase( EC:4.3.2.2 )638719956 9.714379869 10.56709745 1.636 down 0.0014 RRSL_00723 o c Ferredoxin-dependent glutamate synthase( EC:1.4.7.1 )638719957 10.06060487 10.79394745 1.506 down 0.00302 RRSL_00724 o c tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase( EC:2.1.1.61 )638719959 8.600579869 9.361147449 1.535 down 0.024 RRSL_00726 o c Transcriptional regulator, MarR family638719960 8.772729869 7.711897449 2.301 up 0.141 RRSL_00727 o c Transmembrane multidrug resistance transport protein. HLYD family638719961 10.90932987 9.658922449 2.624 up 0.0517 RRSL_00727_1 o c Multidrug resistance protein, MFS family638719962 10.15992987 10.13079745 1.125 up 0.803 RRSL_00728 o c Hypothetical protein638719964 10.68145487 11.25042245 1.344 down 0.211 RRSL_00730 o c NAD(P) transhydrogenase alpha subunit( EC:1.6.1.2 )638719965 12.56715487 12.94582245 1.178 down 0.473 RRSL_00731 o c Aspartate 1-decarboxylase( EC:4.1.1.11 )638719966 11.82760487 12.39419745 1.342 down 0.221 RRSL_00732 o c NAD(P) transhydrogenase alpha subunit( EC:1.6.1.2 )638719967 10.89765487 11.25379745 1.16 down 0.485 RRSL_00733 o c pntB PntB( EC:1.6.1.1 )638719968 12.33612987 12.99262245 1.428 down 0.076 RRSL_00734 o c Two-component response regulator638719969 13.11242987 13.50507245 1.189 down 0.171 RRSL_00736 o c phcB PhcB638719970 11.01285487 11.54049745 1.306 down 0.0148 RRSL_00737 o c phcS PhcS638719971 10.25950487 11.17792245 1.713 down 0.102 RRSL_00738 o c phcR PhcR638719972 11.29260487 12.39232245 1.942 down 0.00917 RRSL_02708 o c Methyltransferase( EC:2.1.1.- )638719973 11.21427987 11.80992245 1.369 down 0.0267 RRSL_02707 o c Hypothetical membrane spanning protein638719976 9.794504869 10.82732245 1.854 down 0.0224 RRSL_02704 o c Rare lipoprotein B precursor (rlpB)638719977 10.95222987 12.05664745 1.948 down 0.0654 RRSL_02703 o c Leucyl-tRNA synthetase( EC:6.1.1.4 )638719979 12.32840487 13.12337245 1.572 down 0.0186 RRSL_02701 o c Hypothetical Protein638719980 12.76077987 13.37537245 1.387 down 0.0852 RRSL_02700 o c fur Fur638719981 13.30140487 13.33337245 1.079 up 0.738 RRSL_02699 o c phcA PhcA638719986 11.17475487 11.49967245 1.135 down 0.307 RRSL_02694 o c surface protein638719987 9.258504869 10.31209745 1.881 down 0.093 RRSL_02693 o c Hypothetical Protein638719988 12.57247987 13.37569745 1.581 down 0.0254 RRSL_02692 o c Hypothetical Protein638719989 13.56822987 14.25632245 1.46 down 0.0167 RRSL_02691 o c Guanyl-specific ribonuclease( EC:3.1.27.3 )638719991 10.07705487 10.68524745 1.381 down 0.178 RRSL_02688 o c Thiamine-monophosphate kinase( EC:2.7.4.16 )638719992 8.038329869 8.867972449 1.61 down 0.0505 RRSL_02686 o c Putative competence-damage protein638719994 11.41127987 12.49119745 1.916 down 0.00614 RRSL_02684 o c Orotidine 5'-phosphate decarboxylase( EC:4.1.1.23 )638719995 10.51197987 10.46327245 1.141 up 0.342 RRSL_02683 o c corA CorA

638719997 9.869529869 9.985197449 1.018 up 0.892 RRSL_02681 o c Monofunctional biosynthetic peptidoglycan transglycosylase( EC:2.4.2.- )638719999 11.94597987 12.88557245 1.738 down 0.00635 RRSL_02679 o c Transporter638720000 8.843079869 9.844122449 1.814 down 0.0207 RRSL_02678 o c Exoribonuclease II( EC:3.1.13.1 )638720001 8.914529869 9.317097449 1.198 down 0.255 RRSL_02677 o c Chorismate--pyruvate lyase( EC:4.- )638720002 10.10027987 11.23107245 1.984 down 0.00693 RRSL_02676 o c Hypothetical protein638720003 13.19075487 13.50142245 1.124 down 0.486 RRSL_02674 o c UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase( EC:6.3.2.- )638720004 9.338004869 10.09767245 1.534 down 0.0209 RRSL_02675 o c Hypothetical Protein638720005 10.16405487 10.98644745 1.602 down 0.0106 RRSL_02673 o c Transmembrane thioredoxin-related protein638720006 12.38122987 12.71687245 1.143 down 0.194 RRSL_02672 o c 3-dehydroquinate dehydratase( EC:4.2.1.10 )638720010 9.818379869 10.88967245 1.904 down 0.00555 RRSL_02668 o c Hypothetical Protein638720015 8.375954869 8.233572449 1.217 up 0.254 RRSL_02661 o c putative hemmaglutinin-related transmembrane protein.638720016 8.762529869 8.370322449 1.447 up 0.181 RRSL_02660 o c Hypothetical Protein638720017 10.63832987 9.400397449 2.602 up 0.0695 RRSL_02659 o c Hypothetical Protein638720019 10.24727987 10.93594745 1.461 down 0.162 RRSL_02657 o c hypothetical protein638720020 11.55052987 10.48989745 2.301 up 0.173 RRSL_02656 o c Transporter, drug/metabolite exporter family638720022 12.95085487 13.61144745 1.432 down 0.0538 RRSL_02653 o c Ribonucleoside-diphosphate reductase beta chain( EC:1.17.4.1 )638720023 11.61392987 12.84307245 2.124 down 0.0657 RRSL_02651 o c Ribonucleoside-diphosphate reductase alpha chain( EC:1.17.4.1 )638720024 8.318904869 8.988247449 1.441 down 0.0299 RRSL_02650 o c anhydro-N-acetylmuramyl-tripeptide amidase638720025 9.373754869 10.41984745 1.871 down 0.0057 RRSL_02649 o c pehR PehR638720026 8.094129869 8.315497449 1.056 down 0.68 RRSL_02648 o c Sensor protein pilS( EC:2.7.3.- )638720027 10.18072987 10.18684745 1.098 up 0.636 RRSL_02646 o c Hypothetical Protein638720028 12.07705487 12.91399745 1.619 down 0.0308 RRSL_02645 o c signal recognition particle, subunit ffh/srp54638720029 11.57437987 12.07342245 1.281 down 0.0898 RRSL_02643 o c Hypoxanthine-guanine phosphoribosyltransferase( EC:2.4.2.8 )638720031 9.013229869 9.731597449 1.491 down 0.00805 RRSL_02641 o c Prolyl 4-hydroxylase alpha subunit( EC:1.14.11.2 )638720032 10.42122987 11.46414745 1.867 down 0.00892 RRSL_02640 o c Soluble lytic murein transglycosylase( EC:3.2.1.- )638720034 9.658054869 10.08259745 1.216 down 0.124 RRSL_02638 o c Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)( EC:3.6.1.17 )638720035 11.90632987 11.88629745 1.118 up 0.177 RRSL_02637 o c Lipoprotein638720036 10.44125487 11.30807245 1.653 down 0.0235 RRSL_02636 o c Glutamate 5-kinase( EC:2.7.2.11 )638720037 11.40652987 12.21694745 1.589 down 0.0592 RRSL_02635 o c GTP-binding protein CgtA (probably involved in DNA repair)638720038 15.19452987 16.09497245 1.692 down 0.00824 RRSL_02634 o c LSU ribosomal protein L27P638720039 16.12670487 16.59417245 1.253 down 0.0151 RRSL_02633 o c LSU ribosomal protein L21P638720040 14.44452987 15.34524745 1.692 down 0.0132 RRSL_03267 o c LSU ribosomal protein L25P638720041 11.13332987 11.96744745 1.615 down 0.0117 RRSL_03268 o c Peptidyl-tRNA hydrolase( EC:3.1.1.29 )638720042 8.559679869 9.264022449 1.476 down 0.021 RRSL_03269 o c Hypothetical Protein638720043 12.15177987 12.85279745 1.473 down 0.00516 RRSL_03270 o c Ferredoxin638720044 11.60165487 12.30022245 1.471 down 0.0297 RRSL_03272 o c Phosphopantetheine adenylyltransferase( EC:2.7.7.3 )638720045 8.390254869 9.272597449 1.67 down 0.00241 RRSL_03273 o c Methyltransferase( EC:2.1.1.- )638720051 9.989129869 9.626222449 1.418 up 0.378 RRSL_03280 o c nitrate transporter, nasF638720052 8.776879869 8.056147449 1.818 up 0.0435 RRSL_03281 o c nrtB NrtB638720053 9.694854869 9.522647449 1.243 up 0.595 RRSL_03282 o c nrtC NrtC638720054 9.404754869 10.39932245 1.806 down 0.00563 RRSL_03283 o c Anthranilate phosphoribosyltransferase trpD3( EC:2.4.2.18 )638720055 9.630929869 10.40604745 1.551 down 0.0671 RRSL_03284 o c Pirin638720057 8.373954869 7.630172449 1.847 up 0.0535 RRSL_03285 o c Sensory box/GGDEF family protein638720059 13.77520487 14.03067245 1.082 down 0.765 RRSL_03288 o c Hypothetical Protein638720060 10.78607987 11.30957245 1.302 down 0.0971 RRSL_03289 o c Protoheme IX farnesyltransferase638720061 10.10420487 10.48859745 1.183 down 0.179 RRSL_03290 o c Heme O monooxygenase (ferredoxin)( EC:1.14.15.- )638720062 11.32115487 11.62037245 1.115 down 0.288 RRSL_03291 o c Hypothetical Protein638720063 10.94052987 10.76949745 1.242 up 0.275 RRSL_03292 o c Cytochrome c oxidase assembly protein Surf1638720064 11.41607987 11.61247245 1.038 down 0.559 RRSL_03293 o c Hypothetical Protein638720065 14.02720487 14.25042245 1.058 down 0.51 RRSL_03294 o c Cytochrome c oxidase polypeptide III( EC:1.9.3.1 )638720066 12.81292987 13.38279745 1.345 down 0.103 RRSL_03295 o c Hypothetical Protein638720067 13.18360487 13.65682245 1.258 down 0.224 RRSL_03296 o c ctaG CtaG638720071 13.21105487 14.02177245 1.589 down 0.0487 RRSL_03300 o c Hypothetical Protein638720072 10.20600487 10.68849745 1.266 down 0.00877 RRSL_03302 o c bioC BioC638720073 7.628254869 7.701097449 1.048 up 0.666 RRSL_03301 o c Amidophosphoribosyltransferase family protein638720074 9.140554869 10.04232245 1.693 down 0.00267 RRSL_03303 o c 23S rRNA methyltransferase( EC:2.1.1.- )638720075 8.377279869 9.316997449 1.738 down 0.0026 RRSL_03304 o c Glycerol-3-phosphate dehydrogenase (NAD(P)+)( EC:1.1.1.94 )

638720077 12.24222987 13.22559745 1.792 down 0.00586 RRSL_03306 o c Glutaredoxin638720078 12.40275487 13.17682245 1.55 down 0.00323 RRSL_03307 o c Rhodanese-related sulfurtransferases638720079 12.76197987 13.76882245 1.821 down 0.00595 RRSL_03308 o c Phosphoglycerate mutase( EC:5.4.2.1 )638720080 13.03907987 14.08939745 1.877 down 0.0234 RRSL_03309 o c Carboxy-terminal processing protease precursor( EC:3.4.21.102 )638720081 8.798754869 9.789447449 1.801 down 0.00156 RRSL_03310 o c Molybdopterin biosynthesis MoeB protein638720082 13.88100487 14.44762245 1.342 down 0.153 RRSL_03311 o c Bacterioferritin638720083 11.85730487 11.69212245 1.237 up 0.159 RRSL_03312 o c Hypothetical Protein638720084 10.74335487 11.96882245 2.119 down 0.0564 RRSL_03313 o c Phosphoenolpyruvate-protein phosphotransferase( EC:2.7.3.9 )638720085 12.85337987 13.68139745 1.609 down 0.00758 RRSL_03314 o c Phosphocarrier protein HPr638720087 12.58160487 13.07267245 1.274 down 0.087 RRSL_03316 o c Glutathione synthetase( EC:6.3.2.3 )638720088 11.73562987 12.78227245 1.872 down 0.0572 RRSL_03317 o c Glutamate--cysteine ligase( EC:6.3.2.2 )638720092 13.18910487 13.43429745 1.074 down 0.567 RRSL_03322 o c Hypothetical protein638720093 11.32330487 10.77532245 1.612 up 0.061 RRSL_03323 o c Hypothetical Protein638720094 8.827179869 8.408347449 1.474 up 0.139 RRSL_03324 o c ATPase related to magnesium chelatase subunit ChlI638720095 15.11157987 15.32194745 1.048 down 0.41 RRSL_03325 o c Polyphenol oxidase A1 precursor( EC:1.10.3.1 )638720096 12.58580487 13.25707245 1.443 down 0.0823 RRSL_03326 o c Hypothetical Protein638720097 8.777454869 9.413647449 1.408 down 0.0505 RRSL_03327 o c Hypothetical Protein638720098 11.49452987 11.73979745 1.074 down 0.541 RRSL_03328 o c ATPase associated with chromosome architecture/replication638720099 11.08150487 11.68704745 1.379 down 0.051 RRSL_03329 o c Hypothetical Protein638720101 8.480679869 8.917972449 1.227 down 0.346 RRSL_03331 o c dctD DctD638720102 7.990354869 8.186572449 1.038 down 0.724 RRSL_03332 o c C4-dicarboxylate transport sensor protein dctB( EC:2.7.3.- )638720103 10.87957987 11.21222245 1.141 down 0.345 RRSL_03333 o c C4-dicarboxylate transport protein638720104 12.11030487 12.94557245 1.617 down 0.0419 RRSL_03334 o c Ferredoxin 2Fe-2S638720105 12.67690487 13.64792245 1.776 down 0.00287 RRSL_03335 o c D-alanyl-D-alanine carboxypeptidase( EC:3.4.16.4 )638720106 10.59462987 11.64789745 1.881 down 0.0123 RRSL_03336 o c Hypothetical transcriptional regulatory protein638720107 8.276479869 8.502697449 1.06 down 0.66 RRSL_03337 o c Transcriptional regulators, LysR family638720108 13.47987987 12.93652245 1.607 up 0.112 RRSL_03338 o c Hypothetical Protein638720109 10.87470487 11.84584745 1.777 down 0.0706 RRSL_03339 o c Lipoate-protein ligase B( EC:6.- )638720110 11.88395487 12.40029745 1.296 down 0.306 RRSL_03340 o c Lipoic acid synthetase( EC:2.8.- )638720126 8.544179869 9.282222449 1.511 down 0.127 RRSL_03355 o c ATPase, AAA family638720139 11.24280487 11.99312245 1.524 down 0.0228 RRSL_03659 o c Hypothetical protein638720143 8.514054869 8.750297449 1.067 down 0.669 RRSL_03663 o c Primosomal protein N638720145 9.775479869 9.549997449 1.289 up 0.104 RRSL_03666 o c Hypothetical Protein638720146 11.49067987 11.39032245 1.182 up 0.101 RRSL_03667 o c Hypothetical protein638720147 9.888129869 9.243222449 1.725 up 0.0391 RRSL_03668 o c Hypothetical Protein638720152 9.306004869 9.015797449 1.349 up 0.445 RRSL_03673 o c Phosphate-binding protein638720153 10.24337987 9.687747449 1.621 up 0.0839 RRSL_03674 o c Hypothetical Protein638720154 8.444954869 9.352872449 1.7 down 0.0273 RRSL_03675 o c Hypothetical Protein638720155 10.01520487 10.90007245 1.673 down 0.0263 RRSL_03676 o c CoA binding protein638720156 10.30280487 11.00907245 1.478 down 0.00829 RRSL_03677 o c Hypothetical Protein638720157 7.940479869 8.768597449 1.609 down 0.0319 RRSL_03678 o c Hypothetical Protein638720160 13.32820487 14.43799745 1.956 down 0.0616 RRSL_03681 o c ATP synthase gamma chain( EC:3.6.3.14 )638720162 14.96942987 15.45654745 1.27 down 0.106 RRSL_03683 o c ATP synthase delta chain( EC:3.6.3.14 )638720163 14.78060487 15.41694745 1.408 down 0.118 RRSL_03684 o c ATP synthase B chain( EC:3.6.3.14 )638720166 12.37075487 13.48107245 1.956 down 0.0193 RRSL_03687 o c Hypothetical Protein638720167 10.00572987 10.78964745 1.56 down 0.0242 RRSL_03688 o c parB ParB638720168 10.73235487 11.57162245 1.621 down 0.00893 RRSL_03689 o c parA ParA638720169 9.578104869 10.70834745 1.984 down 0.00245 RRSL_03690 o c Methyltransferase gidB( EC:2.1.- )638720170 11.00932987 12.07244745 1.893 down 0.00413 RRSL_03691 o c Putative tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase subunit GidA638720173 9.878379869 10.09279745 1.051 down 0.792 RRSL_03694 o c Transcriptional regulators, LysR family638720174 9.622279869 9.364022449 1.319 up 0.158 RRSL_03695 o c Hypothetical protein638720175 8.162204869 8.330572449 1.018 down 0.899 RRSL_03697 o c Transcriptional regulators, LysR family638720189 9.124204869 8.143847449 2.176 up 0.0692 RRSL_03711 o c Salicylaldehyde dehydrogenase( EC:1.2.1.65 )638720206 11.61097987 11.30577245 1.363 up 0.0427 RRSL_03367 o c Acetoacetate decarboxylase( EC:4.1.1.4 )638720230 7.111579869 7.148797449 1.075 up 0.751 RRSL_03394 o c Sigma-54-dependent transcriptional activator638720231 8.976529869 9.921122449 1.744 down 0.00667 RRSL_03395 o c Methylisocitrate lyase( EC:4.1.3.30 )638720233 10.35610487 11.34652245 1.8 down 0.0134 RRSL_03397 o c Aconitate hydratase( EC:4.2.1.3 )

638720245 7.766054869 8.117197449 1.156 down 0.609 RRSL_03410 o c Molybdate-binding protein638720261 11.93377987 11.33557245 1.67 up 0.00345 RRSL_03427 o c Alpha-ketoglutarate permease (kgtP1)638720332 11.11465487 11.77554745 1.433 down 0.18 RRSL_03081 o c Bacterial Peptide Chain Release Factor 3 (RF-3)638720364 8.904404869 9.521147449 1.389 down 0.056 RRSL_02944 o c Hypothetical Protein638720365 7.555354869 7.160622449 1.45 up 0.164 RRSL_02945 o c Glutathione reductase( EC:1.6.4.2 )638720367 12.78062987 12.97554745 1.037 down 0.738 RRSL_02947 o c D-3-phosphoglycerate dehydrogenase( EC:1.1.1.95 )638720368 12.48457987 13.50729745 1.841 down 0.0535 RRSL_02948 o c Phosphoenolpyruvate carboxykinase (GTP)( EC:4.1.1.32 )638720369 11.83672987 11.28897245 1.612 up 0.0229 RRSL_02949 o c phoB PhoB638720370 11.21120487 11.12304745 1.172 up 0.338 RRSL_02950 o c Hypothetical Protein638720371 9.953854869 9.722472449 1.295 up 0.0305 RRSL_02951 o c Hydroxypyruvate isomerase( EC:5.3.1.22 )638720373 8.342854869 8.474572449 1.006 up 0.978 RRSL_02953 o c Two-component sensor histidine kinase( EC:2.7.3.- )638720374 10.36670487 10.16624745 1.267 up 0.669 RRSL_02954 o c Carbon starvation protein A638720375 9.725379869 9.966672449 1.071 down 0.879 RRSL_02955 o c Hypothetical Protein638720376 10.51035487 10.48024745 1.126 up 0.393 RRSL_02956 o c Tetratricopeptide repeat family protein638720377 14.57022987 15.28669745 1.489 down 0.036 RRSL_02957 o c granule-associated protein638720378 9.091904869 9.548197449 1.243 down 0.0978 RRSL_02958 o c Methyltransferase( EC:2.1.1.- )638720379 11.30062987 11.16447245 1.212 up 0.218 RRSL_02960 o c Homoserine O-acetyltransferase( EC:2.3.1.31 )638720380 8.806179869 9.049047449 1.072 down 0.625 RRSL_02961 o c oxidoreductase; succinate-semialdehyde dehydrogenase gabD1( EC:1.2.1.16 )638720382 7.904254869 8.256622449 1.157 down 0.347 RRSL_02963 o c Transcriptional regulator, GntR family / AMINOTRANSFERASE CLASS-I( EC:2.6.1.- )638720386 9.615229869 10.32249745 1.479 down 0.106 RRSL_02967 o c Hypothetical Protein638720387 8.316579869 9.250447449 1.731 down 0.0136 RRSL_02968 o c Phosphoglycolate phosphatase( EC:3.1.3.18 )638720388 11.10587987 11.98922245 1.672 down 0.038 RRSL_02970 o c Acetylglutamate kinase( EC:2.7.2.8 )638720389 12.46275487 12.37047245 1.176 up 0.174 RRSL_02969 o c sigma factor638720390 8.952729869 9.034347449 1.042 up 0.86 RRSL_02971 o c Hypothetical Protein638720391 7.893379869 8.779722449 1.675 down 0.019 RRSL_02972 o c Hypothetical Protein638720393 8.460129869 9.164622449 1.477 down 0.0262 RRSL_02974 o c Sensory transduction protein kinase( EC:2.7.3.- )638720406 9.780479869 10.55034745 1.545 down 0.0265 RRSL_02988 o c Cobyrinic acid a,c-diamide synthase( EC:3.- )638720407 10.44457987 11.19062245 1.52 down 0.0142 RRSL_02989 o c Cob(I)alamin adenosyltransferase( EC:2.5.1.17 )638720410 8.431079869 9.542622449 1.958 down 0.00887 RRSL_02992 o c CbiG protein638720411 8.979579869 10.01934745 1.863 down 0.0113 RRSL_02993 o c Precorrin-4 C11-methyltransferase( EC:2.1.1.133 )638720412 8.913804869 9.490022449 1.351 down 0.0788 RRSL_02994 o c Precorrin-2 C20-methyltransferase( EC:2.1.1.130 )638720413 11.51755487 11.80982245 1.11 down 0.512 RRSL_02995 o c CbiD protein638720417 10.32665487 11.32757245 1.814 down 0.0093 RRSL_02999 o c CobN protein638720424 11.30305487 12.37842245 1.91 down 0.0209 RRSL_03007 o c Lipopolysaccharide heptosyltransferase-1( EC:2.- )638720428 8.620554869 9.565072449 1.744 down 0.00978 RRSL_03190 o c Regulator of nucleoside diphosphate kinase638720432 13.46792987 13.13457245 1.389 up 0.135 RRSL_03194 o c probable transmembrane638720433 10.16365487 10.52089745 1.161 down 0.101 RRSL_03195 o c Heat shock protein 15638720434 9.790129869 10.77944745 1.799 down 0.0026 RRSL_03196 o c Ferrochelatase( EC:4.99.1.1 )638720436 9.154579869 8.549172449 1.678 up 0.0564 RRSL_03198 o c Formiminoglutamase( EC:3.5.3.8 )638720439 11.31875487 8.433872449 8.148 up 0.106 RRSL_03201 o c Histidine utilization repressor638720440 10.85000487 10.42264745 1.483 up 0.3 RRSL_03203 o c hrcA HrcA638720441 8.279254869 9.090272449 1.59 down 0.000945 RRSL_03204 o c recN RecN638720443 9.873754869 10.69869745 1.605 down 0.0275 RRSL_03206 o c Extracellular subtilisin-like protease precursor( EC:3.4.21.- )638720444 11.34210487 12.47897245 1.993 down 0.0167 RRSL_03207 o c Extracellular subtilisin-like protease precursor( EC:3.4.21.- )638720445 10.93987987 10.35749745 1.651 up 0.223 RRSL_03208 o c Hypothetical Protein638720446 8.431629869 8.712997449 1.101 down 0.523 RRSL_03210 o c Glutamate-ammonia-ligase adenylyltransferase( EC:2.7.7.42 )638720447 9.041829869 8.887022449 1.228 up 0.174 RRSL_03209 o c Hypothetical protein638720449 10.78712987 11.53302245 1.52 down 0.0728 RRSL_03212 o c TldD protein638720450 10.61755487 11.39722245 1.556 down 0.0228 RRSL_03213 o c Phospho-2-dehydro-3-deoxyheptonate aldolase( EC:2.5.1.54,EC:4.1.2.15 )638720451 9.258054869 9.914497449 1.428 down 0.00332 RRSL_03215 o c Hypothetical Protein638720452 11.48370487 11.48584745 1.101 up 0.379 RRSL_03216 o c Mechanosensitive ion channel638720453 11.22820487 10.32582245 2.062 up 0.202 RRSL_03218 o c Cobalamin adenosyltransferase family protein638720454 10.75387987 10.94667245 1.036 down 0.702 RRSL_03217 o c (S)-2-hydroxy-acid oxidase chain D( EC:1.1.3.15 )638720455 9.892279869 9.730722449 1.233 up 0.215 RRSL_03219 o c (S)-2-hydroxy-acid oxidase chain D( EC:1.1.3.15 )638720456 7.315229869 7.780872449 1.251 down 0.124 RRSL_03221 o c glycolate oxidase (Fe-S subunit) GlcF( EC:1.1.3.15 )638720459 8.607029869 8.803572449 1.038 down 0.826 RRSL_03224 o c Hypothetical Protein638720460 9.741604869 9.542847449 1.266 up 0.488 RRSL_03225 o c Hypothetical Protein

638720461 8.515754869 9.266722449 1.525 down 0.0982 RRSL_03226 o c Transcriptional regulator, DeoR family638720462 11.82325487 11.43827245 1.44 up 0.0562 RRSL_03227 o c Glutathione peroxidase( EC:1.11.1.9 )638720463 10.20160487 10.93917245 1.511 down 0.0163 RRSL_03228 o c PILI ASSEMBLY PROTEIN PILY1-related638720469 10.93680487 11.35169745 1.208 down 0.343 RRSL_03234 o c pilU PilU638720470 11.02257987 11.85199745 1.61 down 0.0333 RRSL_03235 o c PilT638720471 9.432779869 10.47687245 1.869 down 0.0573 RRSL_03236 o c Hypothetical cytosolic protein638720472 8.610029869 9.243272449 1.405 down 0.19 RRSL_03237 o c Pyrroline-5-carboxylate reductase( EC:1.5.1.2 )638720473 9.292929869 10.26422245 1.777 down 0.0246 RRSL_03239 o c 4-hydroxybenzoate polyprenyltransferase

638720474 15.99515487 16.58334745 1.362 down 0.0141 RRSL_03240 o cNon-specific DNA-binding protein Dps / Iron-binding ferritin-like antioxidant protein / Ferroxidase( EC:1.16.3.1 )

638720493 10.47350487 9.303097449 2.483 up 0.0749 RRSL_03260 o c Hypothetical Protein638720494 7.384979869 8.287947449 1.694 down 0.0107 RRSL_03262 o c ATP-dependent DNA helicase recG( EC:3.6.1.- )638720495 9.085479869 10.04699745 1.765 down 0.00953 RRSL_03263 o c S-adenosylmethionine:tRNA ribosyltransferase-isomerase( EC:5.- )638720496 10.87225487 11.63572245 1.538 down 0.00775 RRSL_03264 o c Queuine tRNA-ribosyltransferase( EC:2.4.2.29 )638720532 8.234629869 8.758897449 1.303 down 0.329 RRSL_02272 o c Indole-3-glycerol phosphate synthase( EC:4.1.1.48 )638720533 7.876904869 8.264897449 1.186 down 0.447 RRSL_02273 o c Anthranilate phosphoribosyltransferase( EC:2.4.2.18 )638720576 10.65942987 11.78934745 1.983 down 0.0522 RRSL_02890 o c Cytochrome c555638720585 10.81800487 9.272122449 3.221 up 0.108 RRSL_02899 o c hypothetical protein638720586 7.712929869 7.486597449 1.29 up 0.304 RRSL_02900 o c Two-component response regulator638720587 9.987504869 10.54334745 1.332 down 0.0195 RRSL_02901 o c czcD CzcD638720590 7.999104869 7.669572449 1.386 up 0.0535 RRSL_02904 o c hypothetical protein638720593 9.941029869 9.097497449 1.979 up 0.179 RRSL_02907 o c Multidrug resistance protein B638720594 7.910179869 8.187497449 1.098 down 0.619 RRSL_02908 o c Mechanosensitive ion channel638720599 10.09395487 10.68352245 1.364 down 0.0119 RRSL_02913 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638720600 10.15715487 9.996747449 1.232 up 0.474 RRSL_02915 o c hypothetical protein638720601 11.36870487 11.11182245 1.318 up 0.217 RRSL_02917 o c hypothetical protein638720603 7.814304869 8.366622449 1.329 down 0.0048 RRSL_02919 o c conserved hypothetical protein638720606 8.814454869 8.752222449 1.151 up 0.416 RRSL_02922 o c hypothetical protein638720616 9.536954869 9.163372449 1.429 up 0.035 RRSL_02791 o c solR SolR638720625 8.801629869 8.701022449 1.182 up 0.431 RRSL_02800 o c Transcriptional regulators, LysR family638720628 8.287004869 9.368372449 1.918 down 0.00343 RRSL_02803 o c Xaa-Pro dipeptidase( EC:3.4.13.9 )638720631 10.58945487 10.82419745 1.066 down 0.684 RRSL_02807 o c Allantoicase( EC:3.5.3.4 )638720633 9.119254869 9.006497449 1.192 up 0.184 RRSL_02809 o c Succinyl-diaminopimelate desuccinylase( EC:3.5.1.18 )638720635 9.728279869 9.845422449 1.017 up 0.854 RRSL_02811 o c Arsenate reductase family protein638720637 9.056129869 9.413847449 1.161 down 0.236 RRSL_02813 o c Hypothetical Protein638720638 10.65252987 11.12034745 1.253 down 0.147 RRSL_02814 o c Hypothetical Protein638720639 9.255754869 9.998972449 1.517 down 0.2 RRSL_02815 o c Rare lipoprotein A638720640 8.722704869 9.350622449 1.4 down 0.0857 RRSL_02816 o c corrin/porphyrin methyltransferase( EC:2.1.1.- )638720641 13.89487987 14.03789745 1 down 0.991 RRSL_02817 o c Hypothetical Protein638720642 9.846354869 10.78587245 1.738 down 0.00324 RRSL_02819 o c Hypothetical Protein638720643 10.14900487 10.38544745 1.067 down 0.791 RRSL_02820 o c soxF SoxF( EC:1.8.5.- )638720644 11.06595487 10.07529745 2.192 up 0.0889 RRSL_02821 o c Cysteine/acetylserine efflux protein638720645 10.05892987 11.09002245 1.852 down 0.00355 RRSL_02822 o c Cytochrome c551638720646 13.18510487 13.29282245 1.023 up 0.709 RRSL_02823 o c Hypothetical transmembrane protein638720647 11.48210487 11.70914745 1.06 down 0.351 RRSL_02824 o c Hypothetical Protein638720648 9.460429869 10.34959745 1.678 down 0.00254 RRSL_02825 o c Hypothetical Protein638720649 9.789854869 10.36949745 1.354 down 0.0259 RRSL_02826 o c Hypothetical Protein638720650 9.673279869 10.12459745 1.239 down 0.00385 RRSL_02827 o c Hypothetical Protein638720651 8.904379869 9.542572449 1.41 down 0.0519 RRSL_02828 o c tlpA TlpA638720659 8.443004869 9.159422449 1.489 down 0.0104 RRSL_02838 o c Spermidine synthase( EC:2.5.1.16 )638720669 7.273504869 7.605147449 1.14 down 0.344 RRSL_02848_5 o c pilV PilV638720670 8.227804869 7.703847449 1.586 up 0.116 RRSL_02849 o c pilW PilW638720673 8.095154869 9.078647449 1.792 down 0.0111 RRSL_02852 o c pilE PilE638720678 11.19087987 11.80189745 1.384 down 0.0282 RRSL_02710 o c Enoyl-CoA hydratase( EC:4.2.1.17 )638720679 12.15265487 12.25527245 1.027 up 0.876 RRSL_02711 o c Enoyl-CoA hydratase( EC:4.2.1.17 )638720681 14.33222987 14.58194745 1.077 down 0.823 RRSL_02714 o c membrane-bound lytic murein transglycosylase a( EC:3.2.1.- )638720683 10.66585487 11.72299745 1.886 down 0.0144 RRSL_02716 o c Ribulose-phosphate 3-epimerase( EC:5.1.3.1 )

638720684 9.797229869 10.50957245 1.485 down 0.0398 RRSL_02717 o c Phosphoglycolate phosphatase gph( EC:3.1.3.18 )

638720686 12.74795487 13.41519745 1.439 down 0.0077 RRSL_02719 o cAnthranilate synthase component II / Para-aminobenzoate synthase glutamine amidotransferase component II( EC:4.1.3.-,EC:4.1.3.27 )

638720688 12.65892987 13.52119745 1.647 down 0.0046 RRSL_02721 o c Anthranilate phosphoribosyltransferase( EC:2.4.2.18 )638720691 10.22260487 11.28417245 1.891 down 0.0141 RRSL_02724 o c Uracil-DNA glycosylase( EC:3.2.2.- )638720692 9.301004869 9.537822449 1.068 down 0.79 RRSL_02725 o c Integral membrane protein638720693 9.547279869 10.16207245 1.388 down 0.0219 RRSL_02726 o c Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain638720694 11.11675487 10.47189745 1.724 up 0.0148 RRSL_02727 o c Alcohol dehydrogenase( EC:1.1.1.1 )638720695 11.10022987 11.60369745 1.285 down 0.121 RRSL_02728 o c Thiol:disulfide interchange protein DsbC638720696 10.78857987 11.29442245 1.287 down 0.0125 RRSL_02729 o c Putative monooxygenase VisC638720698 8.871929869 8.452447449 1.475 up 0.108 RRSL_02731 o c Hypothetical Protein638720700 10.92095487 10.23044745 1.78 up 0.0242 RRSL_02733 o c Hypothetical Protein638720702 10.75730487 10.94052245 1.029 down 0.91 RRSL_02735 o c Hypothetical Protein638720703 11.51962987 11.79092245 1.093 down 0.417 RRSL_02736 o c Glutamyl-tRNA reductase( EC:1.2.1.- )638720704 11.36765487 11.62814745 1.085 down 0.521 RRSL_02737 o c Bacterial Peptide Chain Release Factor 1 (RF-1)638720705 10.97570487 11.79689745 1.601 down 0.129 RRSL_02738 o c Hypothetical Protein638720706 9.862854869 10.30207245 1.229 down 0.0981 RRSL_02739 o c Peptide release factor-glutamine N5-methyltransferase( EC:2.1.1.- )638720707 10.94860487 11.96237245 1.83 down 0.0159 RRSL_02740 o c 3-polyprenyl-4-hydroxybenzoate decarboxylase ubiX( EC:4.1.1.- )638720710 11.17890487 12.00469745 1.606 down 0.00445 RRSL_02743 o c signal peptide, periplasmic glucans biosynthesis protein mdoG638720711 9.435954869 10.19237245 1.531 down 0.0236 RRSL_02744 o c Periplasmic glucan glucosyltransferase( EC:2.4.1.- )638720713 11.75792987 10.91892245 1.973 up 0.0107 RRSL_02746 o c Hypothetical Protein638720714 9.689479869 10.38969745 1.472 down 0.155 RRSL_02747 o c Hypothetical cytosolic protein638720716 10.63722987 11.69629745 1.888 down 0.00893 RRSL_02749 o c cyoD CyoD638720717 11.05927987 12.16889745 1.956 down 0.0139 RRSL_02750 o c Cytochrome O ubiquinol oxidase subunit III( EC:1.10.3.- )638720718 13.11032987 13.85304745 1.516 down 0.0333 RRSL_02751 o c Cytochrome O ubiquinol oxidase subunit I( EC:1.10.3.- )638720719 13.25445487 13.52962245 1.096 down 0.557 RRSL_02752 o c Cytochrome O ubiquinol oxidase subunit II( EC:1.10.3.- )638720720 9.764279869 10.18942245 1.217 down 0.229 RRSL_02753 o c Hypothetical Protein638720722 9.587779869 9.561572449 1.123 up 0.76 RRSL_02755 o c Ferrichrome-iron receptor638720723 8.421129869 8.691197449 1.093 down 0.433 RRSL_02756 o c Gamma-glutamyltranspeptidase( EC:2.3.2.2 )638720724 9.662829869 9.831222449 1.018 down 0.916 RRSL_02757 o c outer membrane heme receptor638720725 10.97262987 10.86229745 1.19 up 0.213 RRSL_02758 o c Sensor protein luxN( EC:2.7.3.- )638720727 13.74135487 14.48767245 1.52 down 0.0408 RRSL_02759 o c Stringent starvation protein B638720729 12.00615487 12.78377245 1.553 down 0.231 RRSL_02761 o c Cytochrome c1638720730 14.85262987 14.73407245 1.197 up 0.00758 RRSL_02762 o c Cytochrome b( EC:1.10.2.2 )638720731 13.85700487 13.97454745 1.016 up 0.919 RRSL_02763 o c petA PetA( EC:1.10.2.2 )638720732 12.61487987 13.13389745 1.298 down 0.274 RRSL_02764 o c Large-conductance mechanosensitive channel638720733 11.02765487 11.97632245 1.749 down 0.0821 RRSL_02765 o c NIF3-related protein638720735 16.86800487 17.09357245 1.059 down 0.192 RRSL_02767 o c Outer membrane porin protein 32 precursor638720736 10.37275487 10.11062245 1.323 up 0.111 RRSL_02769 o c Iron(III)-binding protein638720737 8.676179869 9.155097449 1.263 down 0.223 RRSL_02768 o c Transcriptional regulatory protein638720738 8.772204869 9.403647449 1.404 down 0.0128 RRSL_02770 o c Two component system histidine kinase( EC:2.7.3.- )638720742 9.753504869 9.953972449 1.041 down 0.827 RRSL_02774 o c tatC TatC638720744 12.27397987 13.23562245 1.765 down 0.038 RRSL_02776 o c tatA TatA638720745 14.39345487 14.57824745 1.03 down 0.903 RRSL_02777 o c Hypothetical Protein638720748 12.65125487 13.54032245 1.678 down 0.00753 RRSL_02780 o c Imidazole glycerol phosphate synthase subunit hisF( EC:4.1.3.- )638720749 14.69705487 15.38812245 1.463 down 0.00183 RRSL_02781 o c Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase( EC:5.3.1.16 )638720751 10.76530487 11.49742245 1.505 down 0.0386 RRSL_02783 o c Imidazoleglycerol-phosphate dehydratase( EC:4.2.1.19 )638720759 8.617379869 9.703172449 1.923 down 0.0431 RRSL_02049 o c Zinc metalloprotease( EC:3.4.24.- )638720760 11.31507987 11.76012245 1.234 down 0.241 RRSL_02050 o c Hypothetical protein638720762 15.22287987 16.27902245 1.884 down 0.00513 RRSL_02052 o c 10 kDa chaperonin GROES638720880 9.568504869 9.417572449 1.224 up 0.602 RRSL_02366 o c Hypothetical Protein638720881 12.92207987 13.00742245 1.039 up 0.768 RRSL_02367 o c Hypothetical cytosolic protein638720883 10.50010487 9.712022449 1.904 up 0.244 RRSL_02370 o c tctA TctA638720884 11.05310487 11.44162245 1.186 down 0.523 RRSL_02371 o c Hypothetical Protein638720885 11.53215487 11.56847245 1.075 up 0.749 RRSL_02372 o c Hypothetical membrane spanning protein638720886 8.734854869 9.518297449 1.56 down 0.000907 RRSL_02373 o c CAIB/BAIF family protein638720893 7.940029869 8.328872449 1.186 down 0.471 RRSL_02381 o c Ferrichrome receptor fcuA precursor

638720894 7.885054869 8.115472449 1.063 down 0.729 RRSL_02382 o c Hypothetical Protein638720895 8.697779869 8.406672449 1.349 up 0.0982 RRSL_02383 o c stomatin like protein638720896 9.447254869 8.613872449 1.965 up 0.00201 RRSL_02384 o c nfeD NfeD638720898 9.396904869 8.963997449 1.489 up 0.0387 RRSL_02386 o c Transporter, MFS superfamily638720899 8.336404869 8.856222449 1.299 down 0.106 RRSL_02387 o c Class II Aldolase and Adducin proteins638720900 10.93277987 11.74317245 1.589 down 0.00495 RRSL_02388 o c low-specificity threonine aldolase( EC:4.1.2.5 )638720901 8.425404869 9.145922449 1.493 down 0.0695 RRSL_02389 o c Phosphohydrolase (MutT/nudix family protein)638720902 7.622604869 8.274497449 1.424 down 0.2 RRSL_02390 o c Hypothetical Protein638720903 10.73545487 11.69242245 1.759 down 0.0476 RRSL_02391 o c Cytochrome c638720905 9.806154869 10.58289745 1.552 down 0.129 RRSL_02393 o c Transmembrane threonine efflux protein638720909 12.31790487 13.26602245 1.748 down 0.0394 RRSL_02397 o c Glutathione S-transferase( EC:2.5.1.18 )638720910 12.84720487 13.17537245 1.137 down 0.506 RRSL_02398 o c Hypothetical Protein638720952 8.801029869 9.508622449 1.48 down 0.0708 RRSL_02170 o c Phosphohistidine phosphatase sixA( EC:3.1.3.- )638720953 8.581929869 8.385872449 1.263 up 0.0717 RRSL_02171 o c Hypothetical Protein638720954 11.38600487 12.26817245 1.67 down 0.11 RRSL_02172 o c Exopolyphosphatase( EC:3.6.1.11 )638720956 9.253779869 9.449022449 1.037 down 0.819 RRSL_02174 o c Phosphate regulon sensor protein phoR( EC:2.7.3.- )638720957 10.82557987 10.59829745 1.291 up 0.244 RRSL_02175 o c phoB PhoB638720958 9.929804869 10.08714745 1.01 down 0.97 RRSL_02176 o c phoU PhoU638720959 9.734004869 9.634522449 1.181 up 0.571 RRSL_02177 o c pstB PstB( EC:3.6.3.27 )638720962 10.93045487 10.41477245 1.577 up 0.354 RRSL_02180 o c Phosphate-binding protein638720963 10.97452987 11.96264745 1.798 down 0.0374 RRSL_02181 o c Phosphoglucosamine mutase( EC:5.4.2.10 )638720964 12.06790487 11.88322245 1.253 up 0.168 RRSL_02182 o c Dihydropteroate synthase( EC:2.5.1.15 )638720965 12.25997987 12.94767245 1.46 down 0.188 RRSL_02183 o c Cell division protein ftsH( EC:3.4.24.- )638720966 11.69340487 12.47199745 1.554 down 0.0344 RRSL_02185 o c 23S rRNA Um2552 2'-O-methyltransferase( EC:2.1.1.- )638720972 12.63470487 13.76694745 1.986 down 0.0209 RRSL_02190 o c Carbamoyl-phosphate synthase small chain( EC:6.3.5.5 )638720973 9.459929869 9.194097449 1.326 up 0.0609 RRSL_02191 o c Propionate--CoA ligase( EC:6.2.1.17 )638720975 11.50872987 11.96177245 1.24 down 0.148 RRSL_02194 o c Hydroxyacylglutathione hydrolase( EC:3.1.2.6 )638720976 11.06302987 11.71222245 1.421 down 0.0034 RRSL_02193 o c Methyltransferase( EC:2.1.1.- )638720977 11.55762987 11.27142245 1.345 up 0.0179 RRSL_02196 o c Hypothetical Protein638721017 7.476304869 7.556197449 1.043 up 0.843 RRSL_03127 o c NAD(P) transhydrogenase alpha subunit( EC:1.6.1.2 )638721018 10.27192987 8.793447449 3.074 up 0.0577 RRSL_03126 o c NAD(P) transhydrogenase alpha subunit( EC:1.6.1.2 )638721037 9.045304869 9.606597449 1.337 down 0.115 RRSL_03104 o c prhA PrhA638721082 7.047229869 7.893897449 1.63 down 0.0296 RRSL_03136 o c Biotin carboxylase( EC:6.3.4.14 )638721116 11.59635487 11.75237245 1.009 down 0.949 RRSL_03175 o c Secretion ATPase; CpaF2638721134 9.014079869 10.08007245 1.897 down 0.0546 RRSL_02114 o c morphinone reductase( EC:1.3.1.- )638721135 11.97075487 11.36059745 1.683 up 0.217 RRSL_02115 o c Quinone oxidoreductase( EC:1.6.5.5 )638721136 11.91955487 12.58354745 1.436 down 0.0675 RRSL_02116 o c Acid phosphatase surE( EC:3.1.3.2 )638721137 11.61662987 12.12507245 1.289 down 0.151 RRSL_02117 o c Protein-L-isoaspartate O-methyltransferase( EC:2.1.1.77 )638721138 13.71812987 14.11849745 1.196 down 0.327 RRSL_02118 o c nlpD NlpD638721139 11.80577987 12.24847245 1.231 down 0.499 RRSL_02119 o c rpoS RpoS638721140 10.50537987 10.98759745 1.266 down 0.245 RRSL_02121 o c dioxygenase( EC:1.13.11.- )638721141 9.805379869 10.40369745 1.372 down 0.0692 RRSL_02120 o c 23S rRNA m(5)U 1939 methyltransferase( EC:2.1.1.- )638721143 15.36572987 15.84207245 1.261 down 0.0457 RRSL_02123 o c Nucleoside diphosphate kinase( EC:2.7.4.6 )638721144 10.74650487 11.84762245 1.944 down 0.112 RRSL_02124 o c Radical SAM family enzyme638721145 12.15880487 12.51532245 1.16 down 0.451 RRSL_02125 o c PilF protein638721146 10.34712987 11.16749745 1.6 down 0.0954 RRSL_02126 o c Transcriptional regulator638721147 11.00110487 11.75679745 1.53 down 0.211 RRSL_02127 o c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase638721148 10.32670487 11.46387245 1.993 down 0.0129 RRSL_02128 o c Histidyl-tRNA synthetase( EC:6.1.1.21 )638721149 12.66952987 13.32592245 1.428 down 0.108 RRSL_02129 o c Hypothetical Protein638721150 11.02190487 12.12849745 1.951 down 0.0682 RRSL_02130 o c quinoprotein dehydrogenase638721151 9.496379869 10.41329745 1.711 down 0.0525 RRSL_02131 o c GTP-binding protein638721152 16.30595487 16.08624745 1.284 up 0.00224 RRSL_02132 o c Hypothetical Protein638721153 12.51132987 13.29837245 1.564 down 0.12 RRSL_02133 o c hflX HflX638721155 11.90775487 12.77449745 1.652 down 0.0418 RRSL_02135 o c Protease activity modulator HflC638721156 10.64967987 11.01309745 1.166 down 0.184 RRSL_02136 o c Hypothetical Protein638721158 13.34985487 13.69414745 1.15 down 0.372 RRSL_02138 o c Adenylosuccinate synthetase( EC:6.3.4.4 )638721159 13.37467987 13.66484745 1.108 down 0.415 RRSL_02139 o c Xanthine-guanine phosphoribosyltransferase( EC:2.4.2.22 )

638721161 12.66032987 12.42787245 1.296 up 0.174 RRSL_02140 o c Ribonuclease R( EC:3.1.- )638721162 10.06570487 11.03154745 1.77 down 0.076 RRSL_02141 o c 23S rRNA Gm2251 methyltransferase( EC:2.1.1.- )638721163 9.880454869 10.79804745 1.712 down 0.0774 RRSL_02142 o c SIR2 family protein638721164 11.92410487 12.74189745 1.597 down 0.0639 RRSL_02143 o c Transaldolase( EC:2.2.1.2 )638721166 11.67545487 10.68287245 2.195 up 0.177 RRSL_02145 o c Cytosine/uracil/thiamine/allantoin permease family protein638721167 8.076279869 7.318672449 1.865 up 0.0774 RRSL_02147 o c Probable transmembrane methyl-accepting chemotaxis protein638721168 12.04512987 12.79294745 1.522 down 0.0554 RRSL_02148 o c yggX YggX638721188 10.53427987 10.81519745 1.101 down 0.659 RRSL_02168 o c Amino-acid acetyltransferase( EC:2.3.1.1 )638721201 10.05447987 10.47612245 1.214 down 0.245 RRSL_02527 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638721209 14.15490487 14.76517245 1.383 down 0.0249 RRSL_02537 o c Agmatinase( EC:3.5.3.11 )638721222 8.192504869 8.264097449 1.049 up 0.79 RRSL_02552 o c hypothetical protein638721223 8.941454869 8.767497449 1.244 up 0.337 RRSL_02553 o c hypothetical protein638721224 8.573679869 8.350447449 1.287 up 0.11 RRSL_02554 o c Serine protease( EC:3.4.21.- )638721225 7.048679869 7.636072449 1.361 down 0.0198 RRSL_02555 o c rtcR RtcR638721227 9.380704869 9.913847449 1.311 down 0.2 RRSL_02557 o c hypothetical protein638721228 8.962004869 9.767747449 1.584 down 0.161 RRSL_02558 o c Hypothetical cytosolic protein638721229 7.095079869 7.441972449 1.152 down 0.323 RRSL_02559 o c RNA 3'-terminal phosphate cyclase( EC:6.5.1.4 )638721231 10.00347987 11.03077245 1.847 down 0.00224 RRSL_02561 o c Transcriptional regulatory protein638721233 8.491554869 8.369347449 1.2 up 0.0856 RRSL_02563 o c Low temperature requirement protein A638721234 10.47402987 9.708897449 1.874 up 0.0734 RRSL_02564 o c Transmembrane (Homoserine/ Homoserine Lactone) Efflux protein638721238 10.37577987 10.07154745 1.362 up 0.192 RRSL_02568 o c hypothetical protein638721239 8.995179869 10.04514745 1.876 down 0.032 RRSL_02569 o c hypothetical protein

638721240 9.278529869 9.013472449 1.325 up 0.0229 RRSL_02570 o cMethylmalonyl-CoA mutase coenzyme B12-binding subunit / LAO/AO transport system kinase / Methylmalonyl-CoA mutase alpha subunit( EC:2.7.-,EC:5.4.99.2 )

638721242 9.594679869 9.205522449 1.444 up 0.264 RRSL_02573 o c hypothetical protein638721265 9.923304869 10.15697245 1.065 down 0.689 RRSL_02471 o c Glutathione-S-transferases638721266 9.772154869 10.51054745 1.512 down 0.00652 RRSL_02472 o c Aspartate aminotransferase( EC:2.6.1.1 )638721267 12.02162987 10.31972245 3.589 up 0.0861 RRSL_02473 o c yaaA YaaA638721268 9.465054869 10.43044745 1.769 down 0.00509 RRSL_02475 o c Zinc-carboxypeptidase precursor( EC:3.4.17.- )638721269 10.96495487 12.04354745 1.914 down 0.0126 RRSL_02476 o c probable transmembrane lipoprotein638721273 9.980129869 11.00927245 1.849 down 0.0564 RRSL_02481 o c 2-methylcitrate dehydratase / 2-methylisocitrate dehydratase( EC:4.2.1.79,EC:4.2.1.99 )638721276 8.624479869 9.403322449 1.555 down 0.0865 RRSL_02484 o c Methylisocitrate lyase( EC:4.1.3.30 )638721277 10.21052987 10.53387245 1.134 down 0.467 RRSL_02485 o c Malate--CoA ligase alpha chain( EC:6.2.1.9 )638721278 13.71780487 14.73564745 1.835 down 0.0402 RRSL_02486 o c Malate dehydrogenase( EC:1.1.1.37,EC:1.1.1.82 )638721279 9.305379869 9.774222449 1.254 down 0.239 RRSL_02487 o c Transcriptional regulator, GntR family638721280 15.76610487 16.15807245 1.189 down 0.0289 RRSL_02488 o c Hypothetical Protein638721281 14.14717987 14.85499745 1.48 down 0.0858 RRSL_02489 o c Succinate dehydrogenase membrane anchor subunit( EC:1.3.99.1 )638721285 13.47455487 14.44939745 1.781 down 0.038 RRSL_02493 o c Citrate synthase( EC:2.3.3.1,EC:4.1.3.7 )638721286 9.853779869 10.91724745 1.894 down 0.0468 RRSL_02494 o c leuC LeuC( EC:4.2.1.33 )638721287 12.33297987 12.93914745 1.379 down 0.0624 RRSL_02495 o c 3-isopropylmalate dehydratase small subunit( EC:4.2.1.33 )638721288 10.92370487 11.78779745 1.649 down 0.057 RRSL_02496 o c 3-isopropylmalate dehydrogenase( EC:1.1.1.85 )638721291 10.50297987 10.83159745 1.138 down 0.204 RRSL_02500 o c tRNA pseudouridine synthase A( EC:4.2.1.70 )638721292 10.87300487 11.31627245 1.232 down 0.105 RRSL_02501 o c N-(5'-phosphoribosyl)anthranilate isomerase( EC:5.3.1.24 )638721293 11.51845487 12.09467245 1.351 down 0.0137 RRSL_02502 o c Tryptophan synthase beta chain( EC:4.2.1.20 )638721294 11.84222987 12.39214745 1.327 down 0.0185 RRSL_02504 o c Tryptophan synthase alpha chain( EC:4.2.1.20 )638721295 13.43287987 14.23727245 1.583 down 0.0297 RRSL_02505 o c Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta( EC:6.4.1.2 )638721296 10.58397987 11.10247245 1.298 down 0.0893 RRSL_02506 o c folylpolyglutamate synthase / dihydrofolate synthase( EC:6.3.2.12,EC:6.3.2.17 )638721297 9.873379869 10.95564745 1.919 down 0.0155 RRSL_02507 o c probable transmembrane protein638721298 12.62167987 12.67309745 1.064 up 0.442 RRSL_02508 o c Colicin V production protein638721300 10.98267987 11.08447245 1.028 up 0.804 RRSL_02510 o c ABC transporter transmembrane permease protein638721301 10.13987987 10.79887245 1.431 down 0.0123 RRSL_02511 o c Putative bacteriocin export ATP-binding protein638721340 8.149254869 7.719072449 1.486 up 0.248 RRSL_01770 o c DNA polymerase III alpha subunit( EC:2.7.7.7 )638721346 15.64990487 16.25652245 1.38 down 0.00862 RRSL_01832 o c LSU ribosomal protein L3P638721347 14.89552987 15.79792245 1.694 down 0.00574 RRSL_01833 o c LSU ribosomal protein L1E (= L4P)638721348 16.04682987 16.61647245 1.345 down 0.00388 RRSL_01834 o c LSU ribosomal protein L23P638721349 14.86730487 15.75874745 1.681 down 0.00917 RRSL_01835 o c LSU ribosomal protein L2P638721350 15.78322987 16.46782245 1.456 down 0.00953 RRSL_01836 o c SSU ribosomal protein S19P

638721351 15.60440487 16.15874745 1.331 down 0.0204 RRSL_01837 o c LSU ribosomal protein L22P638721353 15.12087987 15.90787245 1.564 down 0.0133 RRSL_01839 o c LSU ribosomal protein L16P638721354 15.78227987 16.20909745 1.218 down 0.0646 RRSL_01840 o c LSU ribosomal protein L29P638721355 15.01572987 15.66162245 1.418 down 0.0131 RRSL_01841 o c SSU ribosomal protein S17P638721360 14.42550487 15.42702245 1.814 down 0.0157 RRSL_01846 o c SSU ribosomal protein S8P638721361 14.44657987 15.14859745 1.474 down 0.0377 RRSL_01847 o c LSU ribosomal protein L6P638721362 14.63987987 15.57074745 1.728 down 0.0218 RRSL_01848 o c LSU ribosomal protein L18P638721363 15.50332987 16.11062245 1.38 down 0.000652 RRSL_01849 o c SSU ribosomal protein S5P638721364 15.86057987 16.39564745 1.313 down 0.0125 RRSL_01850 o c LSU ribosomal protein L30P638721365 13.16775487 14.39847245 2.127 down 0.0569 RRSL_01851 o c LSU ribosomal protein L15P638721366 16.65260487 16.72137245 1.051 up 0.641 RRSL_01852 o c Protein translocase subunit secY638721367 16.06892987 15.95504745 1.193 up 0.0939 RRSL_01853 o c Bacterial Protein Translation Initiation Factor 1 (IF-1)638721369 16.20945487 16.50359745 1.111 down 0.102 RRSL_01855 o c SSU ribosomal protein S13P638721371 15.27327987 15.64482245 1.172 down 0.184 RRSL_01857 o c SSU ribosomal protein S4P638721372 14.31137987 15.18202245 1.657 down 0.0295 RRSL_01858 o c DNA-directed RNA polymerase alpha chain( EC:2.7.7.6 )638721373 16.15065487 16.60992245 1.246 down 0.0329 RRSL_01859 o c LSU ribosomal protein L17P638721374 11.86400487 12.09867245 1.066 down 0.615 RRSL_01860 o c Cu(2+)-binding protein CutA638721375 11.32592987 11.95074745 1.397 down 0.00241 RRSL_01861 o c Thiol:disulfide interchange protein DsbD638721376 11.00785487 12.02804745 1.838 down 0.0463 RRSL_01862 o c Delta-aminolevulinic acid dehydratase hemB( EC:4.2.1.24 )638721377 11.27550487 12.00834745 1.506 down 0.118 RRSL_01863 o c GTP-binding protein YihA638721379 9.635579869 10.16562245 1.308 down 0.000906 RRSL_01866 o c Heme export protein ResB638721380 11.94357987 12.07017245 1.01 up 0.931 RRSL_01867 o c Heme export protein ResC / Apocytochrome heme-lyase638721381 11.52602987 12.19064745 1.436 down 0.133 RRSL_01868 o c ATP/GTP binding protein638721382 7.322254869 8.315372449 1.804 down 0.0212 RRSL_01869 o c RNA polymerase ECF-type sigma factor638721383 9.805104869 10.03699745 1.064 down 0.468 RRSL_01870 o c Transcriptional regulator638721384 11.77150487 11.83744745 1.053 up 0.814 RRSL_01871 o c Transmembrane hypothetical protein638721385 9.832079869 9.465022449 1.422 up 0.204 RRSL_01872 o c Bicyclomycin resistance protein638721389 10.00040487 11.05272245 1.879 down 0.00389 RRSL_01876 o c Multimodular transpeptidase-transglycosylase PBP 1A638721390 13.17687987 13.56649745 1.187 down 0.225 RRSL_01877 o c pilM PilM638721391 10.90570487 11.45294745 1.324 down 0.0553 RRSL_01878 o c pilN PilN638721392 12.86610487 13.05912245 1.036 down 0.806 RRSL_01879 o c pilO PilO638721393 12.86060487 13.55459745 1.466 down 0.00555 RRSL_01880 o c pilP PilP638721394 11.62355487 12.68814745 1.895 down 0.0181 RRSL_01881 o c pilQ PilQ638721395 12.20510487 12.56679745 1.164 down 0.365 RRSL_01884 o c 3-dehydroquinate synthase( EC:4.2.3.4,EC:4.6.1.3 )638721396 11.10615487 10.82594745 1.339 up 0.116 RRSL_01885 o c Deoxyguanosinetriphosphate triphosphohydrolase( EC:3.1.5.1 )638721398 10.00557987 9.633572449 1.427 up 0.211 RRSL_01887 o c Hypothetical cytosolic protein638721399 10.53337987 10.80644745 1.095 down 0.625 RRSL_01888 o c Glutamate synthase [NADPH] large chain( EC:1.4.1.13 )638721400 10.47402987 10.50117245 1.082 up 0.647 RRSL_01889 o c Glutamate synthase [NADPH] small chain( EC:1.4.1.13 )638721401 8.468079869 7.902122449 1.633 up 0.0649 RRSL_01890 o c Plasmid pENH91 DNA, SacI-KpnI region containing chlorocatechol degradative operon638721403 11.41775487 11.81754745 1.195 down 0.0659 RRSL_01892 o c toluene tolerance protein TTG2B638721404 14.15390487 14.24422245 1.036 up 0.845 RRSL_01893 o c toluene tolerance protein TTG2C638721405 13.83945487 14.28932245 1.238 down 0.0375 RRSL_01894 o c Lipoprotein638721408 11.19847987 11.85119745 1.425 down 0.0651 RRSL_01897 o c ABC transporter ATP-binding protein638721409 10.85212987 11.34217245 1.273 down 0.0531 RRSL_01898 o c ABC transporter permease protein638721410 12.44160487 13.13919745 1.47 down 0.00634 RRSL_01899 o c BolA protein638721411 12.01805487 12.76609745 1.522 down 0.0209 RRSL_01900 o c UDP-N-acetylglucosamine 1-carboxyvinyltransferase( EC:2.5.1.7 )638721414 10.41500487 11.40112245 1.795 down 0.0196 RRSL_01903 o c Histidinol-phosphate aminotransferase( EC:2.6.1.9 )638721417 9.421529869 8.950922449 1.528 up 0.0351 RRSL_01906 o c tRNA(Ile)-lysidine synthetase TilS638721418 12.82905487 13.16484745 1.144 down 0.0837 RRSL_01907 o c Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha( EC:6.4.1.2 )638721419 10.89432987 11.39112245 1.279 down 0.105 RRSL_01908 o c DNA-3-methyladenine glycosylase II( EC:3.2.2.21 )638721420 11.77555487 12.44632245 1.443 down 0.117 RRSL_01909 o c Cysteinyl-tRNA synthetase( EC:6.1.1.16 )638721421 11.50975487 10.72442245 1.901 up 0.228 RRSL_01910 o c Tetratricopeptide repeat family protein638721422 14.97775487 15.24949745 1.094 down 0.198 RRSL_01911 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638721423 13.63767987 14.29849745 1.433 down 0.0265 RRSL_01912 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638721424 9.766629869 10.08714745 1.131 down 0.447 RRSL_01913 o c UDP-2,3-diacylglucosamine hydrolase( EC:3.6.1.- )638721425 9.856354869 10.74077245 1.673 down 0.0616 RRSL_01914 o c Serine acetyltransferase( EC:2.3.1.30 )638721426 11.10410487 11.56357245 1.246 down 0.0849 RRSL_01916 o c RRNA methylase, SpoU family

638721428 9.021479869 9.939497449 1.712 down 0.0114 RRSL_01917 o c Transcriptional regulator, MerR family638721429 10.18715487 11.28454745 1.939 down 0.024 RRSL_01918 o c GMP synthase (glutamine-hydrolyzing)( EC:6.3.5.2 )638721431 9.501629869 10.42539745 1.719 down 0.0306 RRSL_01920 o c Hypothetical cytosolic protein638721433 8.276704869 7.703172449 1.641 up 0.132 RRSL_01922 o c Probable transmembrane methyl-accepting chemotaxis protein638721437 10.35282987 11.49364745 1.998 down 0.00609 RRSL_01926 o c mutS MutS638721439 13.34620487 13.69442245 1.153 down 0.482 RRSL_01929 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638721440 11.14400487 11.77569745 1.404 down 0.0404 RRSL_01928 o c Hypothetical cytosolic protein638721443 12.27402987 13.30179745 1.848 down 0.00853 RRSL_01933 o c Dihydrodipicolinate synthase( EC:4.2.1.52 )638721445 10.81572987 11.84212245 1.846 down 0.0297 RRSL_01935 o c Tryptophanyl-tRNA synthetase( EC:6.1.1.2 )638721446 12.05067987 11.82912245 1.286 up 0.18 RRSL_01936 o c Membrane metalloprotease638721447 9.350729869 10.12967245 1.555 down 0.00019 RRSL_01937 o c Sua5/YciO/YrdC/YwlC family protein638721451 10.43840487 9.324897449 2.387 up 0.0727 RRSL_01942 o c Esterase( EC:3.1.1.1 )638721452 9.582129869 10.04779745 1.251 down 0.04 RRSL_01944 o c Hypothetical protein638721453 11.44645487 11.77299745 1.136 down 0.274 RRSL_01943 o c Putative acetyltransferase/acyltransferase638721454 11.24495487 11.78292245 1.316 down 0.0446 RRSL_01945 o c 33 kDa chaperonin638721455 10.81900487 11.05967245 1.071 down 0.401 RRSL_01946 o c Hypothetical Protein638721456 13.87962987 13.16592245 1.809 up 0.00724 RRSL_01947 o c ftsB FtsB638721457 12.55812987 13.19234745 1.406 down 0.124 RRSL_01948 o c Enolase( EC:4.2.1.11 )638721458 10.91490487 11.82379745 1.701 down 0.0651 RRSL_01949 o c Hypothetical cytosolic protein638721459 12.11520487 12.93082245 1.595 down 0.0656 RRSL_01950 o c 2-dehydro-3-deoxyphosphooctonate aldolase( EC:2.5.1.55,EC:4.1.2.16 )638721460 12.18190487 12.93499745 1.527 down 0.118 RRSL_01951 o c CTP synthase; pyrG( EC:6.3.4.2 )638721461 8.972504869 9.245397449 1.095 down 0.653 RRSL_01952 o c Putative hydrolase638721462 11.94102987 11.83994745 1.183 up 0.0266 RRSL_01953 o c Hypothetical protein638721463 9.200704869 10.13999745 1.738 down 0.0218 RRSL_01954 o c Transglutaminase-like enzymes, putative cysteine proteases638721464 10.30612987 10.64329745 1.145 down 0.167 RRSL_01955 o c Hypothetical protein638721465 9.745429869 10.26379745 1.298 down 0.0429 RRSL_01956 o c Hypothetical cytosolic protein638721466 7.926479869 7.982247449 1.061 up 0.726 RRSL_01957 o c DNA translocation competence protein ComA638721467 8.975629869 9.878472449 1.694 down 0.04 RRSL_01958 o c Sec-independent protein translocase protein tatD( EC:3.1.21.- )638721470 9.049954869 9.862472449 1.591 down 0.0163 RRSL_01960 o c Single-stranded-DNA-specific exonuclease recJ( EC:3.1.- )638721476 12.57490487 12.53104745 1.137 up 0.272 RRSL_02580 o c hypothetical protein638721477 9.086554869 9.885072449 1.576 down 0.0399 RRSL_02581 o c FAD/FMN-containing dehydrogenases638721479 10.93697987 11.59072245 1.426 down 0.0239 RRSL_02583 o c Ribonuclease BN( EC:3.1.- )638721480 11.96582987 11.69187245 1.333 up 0.113 RRSL_02584 o c hypothetical protein638721481 8.387454869 8.826672449 1.229 down 0.28 RRSL_02586 o c O-acetylhomoserine sulfhydrylase / O-acetylserine sulfhydrylase( EC:4.2.99.10,EC:4.2.99.8 )638721482 12.96305487 13.36112245 1.194 down 0.416 RRSL_02587 o c CBS domain containing protein638721483 10.38340487 11.34472245 1.764 down 0.000568 RRSL_02588 o c Macrolide-efflux protein / 1-acyl-sn-glycerol-3-phosphate acyltransferase( EC:2.3.1.51 )638721484 11.87760487 12.72607245 1.632 down 0.0512 RRSL_02589 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638721486 9.894529869 10.68354745 1.566 down 0.0112 RRSL_02591 o c Electron transfer flavoprotein-ubiquinone oxidoreductase( EC:1.5.5.1 )638721487 12.00900487 12.43899745 1.221 down 0.123 RRSL_02592 o c Gluconate 5-dehydrogenase( EC:1.1.1.69 )638721488 9.119279869 9.687372449 1.343 down 0.12 RRSL_02593 o c hypothetical protein638721489 12.62550487 12.70769745 1.042 up 0.798 RRSL_02594 o c hypothetical protein638721490 12.63855487 12.57064745 1.156 up 0.389 RRSL_02595 o c hypothetical protein638721491 10.16712987 10.77502245 1.381 down 0.273 RRSL_02596 o c D-beta-hydroxybutyrate dehydrogenase( EC:1.1.1.30 )

638721493 9.687429869 10.67842245 1.801 down 0.0621 RRSL_02598 o cGTP pyrophosphokinase / Guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase( EC:2.7.6.5,EC:3.1.7.2 )

638721495 12.08312987 13.18092245 1.94 down 0.0415 RRSL_02599 o c Threonyl-tRNA synthetase( EC:6.1.1.3 )638721496 15.59277987 15.35912245 1.297 up 0.0265 RRSL_02601 o c Bacterial Protein Translation Initiation Factor 3 (IF-3)638721497 16.55077987 16.77204745 1.056 down 0.0761 RRSL_02602 o c LSU ribosomal protein L35P638721498 14.36732987 14.73622245 1.17 down 0.598 RRSL_02603 o c LSU ribosomal protein L20P638721499 12.34072987 13.16617245 1.606 down 0.0819 RRSL_02604 o c Phenylalanyl-tRNA synthetase alpha chain( EC:6.1.1.20 )638721500 13.93557987 14.57967245 1.416 down 0.0208 RRSL_02605 o c Phenylalanyl-tRNA synthetase beta chain( EC:6.1.1.20 )638721502 10.84070487 11.76604745 1.721 down 0.158 RRSL_02607 o c Transcriptional regulator, MerR family638721527 12.31542987 13.21964745 1.696 down 0.00119 RRSL_01675 o c Hypothetical membrane spanning protein638721529 8.632429869 9.709047449 1.911 down 0.0197 RRSL_01677 o c Glutamate racemase( EC:5.1.1.3 )638721530 11.95597987 12.55159745 1.369 down 0.185 RRSL_01678 o c C4-dicarboxylate transport protein638721531 9.509779869 9.316247449 1.261 up 0.21 RRSL_01679 o c Hypothetical Protein638721532 10.43555487 10.28897245 1.221 up 0.121 RRSL_01680 o c Transcriptional regulator, ArsR family

638721533 7.715979869 7.140122449 1.644 up 0.0198 RRSL_01681 o c ATP-dependent Zn proteases638721534 13.81560487 14.02592245 1.048 down 0.686 RRSL_01682 o c TonB protein638721535 11.43100487 12.45669745 1.845 down 0.0318 RRSL_01683 o c TolQ protein638721536 11.25832987 11.98954745 1.504 down 0.0578 RRSL_01684 o c Hypothetical Protein638721537 13.64315487 14.74074745 1.939 down 0.0101 RRSL_01685 o c Hypothetical Protein638721538 11.82242987 12.42842245 1.379 down 0.00148 RRSL_01686 o c glcG GlcG638721539 9.665729869 9.983922449 1.13 down 0.596 RRSL_01687 o c Integral membrane protein638721540 12.32520487 11.56424745 1.869 up 0.0294 RRSL_01688 o c Hypothetical Protein638721541 8.688029869 8.121472449 1.633 up 0.0901 RRSL_01689 o c Hypothetical Protein638721551 15.77370487 15.70157245 1.159 up 0.487 RRSL_01699 o c Peroxiredoxin( EC:1.11.- )638721552 11.46990487 11.83649745 1.168 down 0.305 RRSL_01700 o c Peroxiredoxin reductase (NAD(P)H)( EC:1.6.4.- )638721553 9.692729869 9.704422449 1.094 up 0.534 RRSL_01702 o c Ferric uptake regulation protein638721557 9.050004869 9.696447449 1.418 down 0.0218 RRSL_01706 o c Ferrous iron transport protein B638721565 9.226054869 8.838172449 1.443 up 0.318 RRSL_01714 o c Pyrrolidone-carboxylate peptidase( EC:3.4.19.3 )638721582 10.60725487 11.46272245 1.64 down 0.109 RRSL_01779 o c paaA PaaA638721583 7.295579869 8.078797449 1.559 down 0.143 RRSL_01781 o c paaC PaaC638721584 9.130104869 9.028247449 1.183 up 0.417 RRSL_01782 o c Phenylacetyl-CoA 2-monooxygenase electron transfer component( EC:1.14.13.- )638721630 12.48392987 12.34324745 1.216 up 0.00918 RRSL_01145 o c CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase( EC:2.7.8.5 )638721631 9.290329869 9.664547449 1.174 down 0.289 RRSL_01146 o c Excinuclease ABC subunit C638721632 10.43360487 10.78884745 1.159 down 0.366 RRSL_01147 o c Hypothetical cytosolic protein638721633 14.25170487 14.77162245 1.299 down 0.167 RRSL_01148 o c Protein Translation Elongation Factor P (EF-P)638721634 9.650229869 10.71794745 1.9 down 0.0372 RRSL_01149 o c Anhydromuramoyl-peptide exo-beta-N-acetylglucosaminidase( EC:3.2.1.-,EC:3.2.1.52 )638721637 9.736679869 10.29767245 1.337 down 0.0427 RRSL_01152 o c recO RecO638721638 11.49462987 12.36452245 1.656 down 0.135 RRSL_01153 o c era Era638721639 11.18235487 11.51534745 1.141 down 0.607 RRSL_01154 o c Ribonuclease III( EC:3.1.26.3 )638721640 13.50307987 13.94642245 1.232 down 0.196 RRSL_01155 o c Hypothetical Protein638721641 12.89200487 13.54609745 1.426 down 0.0028 RRSL_01156 o c Signal peptidase I( EC:3.4.21.89 )638721642 12.09305487 12.54739745 1.241 down 0.247 RRSL_01157 o c lepA LepA638721643 11.08652987 11.95379745 1.653 down 0.0702 RRSL_01158 o c Glutaredoxin638721644 12.83922987 13.71529745 1.663 down 0.0852 RRSL_01159 o c Protease Do( EC:3.4.21.- )638721645 13.24260487 13.66807245 1.217 down 0.235 RRSL_01160 o c Sigma-E factor regulatory protein rseB precursor638721646 13.81832987 14.33494745 1.296 down 0.169 RRSL_01161 o c Hypothetical Protein638721647 12.94102987 13.51727245 1.351 down 0.229 RRSL_01162 o c RNA polymerase sigma-E factor638721648 14.77917987 14.97807245 1.04 down 0.716 RRSL_01165 o c 3-oxoacyl-[acyl-carrier-protein] synthase( EC:2.3.1.41 )638721649 14.15327987 15.20389745 1.877 down 0.0143 RRSL_01166 o c 3-oxoacyl-[acyl-carrier protein] reductase( EC:1.1.1.100 )638721653 14.53622987 15.03084745 1.277 down 0.239 RRSL_01170 o c LSU ribosomal protein L32P638721654 15.45570487 15.75864745 1.118 down 0.653 RRSL_01171 o c Hypothetical Protein638721657 10.47070487 11.50117245 1.851 down 0.000587 RRSL_01174 o c protease IV( EC:3.4.- )638721658 11.85122987 12.02667245 1.023 down 0.896 RRSL_01175 o c Rieske (2Fe-2S) domain protein638721659 8.616004869 9.596347449 1.788 down 0.0253 RRSL_01176 o c Hypothetical Protein638721660 10.17172987 11.12787245 1.758 down 0.0364 RRSL_01177 o c Ribosomal large subunit pseudouridine synthase C( EC:4.2.1.70 )638721661 11.18085487 12.49902245 2.26 down 0.0895 RRSL_01178 o c Ribonuclease E( EC:3.1.4.- )638721662 10.03767987 10.52884745 1.274 down 0.206 RRSL_01179 o c Molybdenum cofactor biosynthesis protein A638721663 9.836704869 10.24557245 1.203 down 0.193 RRSL_01180 o c Molybdopterin-guanine dinucleotide biosynthesis protein A638721664 10.04900487 9.981097449 1.156 up 0.11 RRSL_01181 o c Molybdopterin biosynthesis MoeA protein638721665 13.38667987 13.39777245 1.094 up 0.794 RRSL_01182 o c Hypothetical Protein638721666 10.41155487 10.71199745 1.116 down 0.312 RRSL_01183 o c RmuC family protein638721667 9.557829869 9.965022449 1.202 down 0.36 RRSL_01185 o c 2-hydroxyacid dehydrogenase( EC:1.1.1.- )638721668 9.635279869 10.01267245 1.177 down 0.347 RRSL_01186 o c Hypothetical protein638721670 10.43590487 11.07792245 1.414 down 0.042 RRSL_01188 o c Nicotinate phosphoribosyltransferase( EC:2.4.2.11 )638721674 12.90220487 13.87497245 1.779 down 0.0025 RRSL_01192 o c Lysyl-tRNA synthetase( EC:6.1.1.6 )638721676 11.73437987 11.70242245 1.127 up 0.57 RRSL_01194 o c Hypothetical cytosolic protein638721677 10.73612987 11.52144745 1.562 down 0.0073 RRSL_01195 o c Ferredoxin, 2Fe-2s638721678 8.252279869 9.166222449 1.707 down 0.00829 RRSL_01196 o c hscA HscA638721679 9.403754869 10.08614745 1.454 down 0.0475 RRSL_01197 o c hscB HscB638721680 10.19610487 11.19109745 1.806 down 0.0408 RRSL_01198 o c Hypothetical Protein638721681 12.39735487 12.64627245 1.077 down 0.71 RRSL_01199 o c HesB protein family

638721682 14.01607987 14.03742245 1.086 up 0.497 RRSL_01200 o c IscU protein638721684 11.07965487 11.75247245 1.445 down 0.214 RRSL_01202 o c Cysteine desulfhydrase / Selenocysteine lyase( EC:4.4.1.16 )638721689 9.638779869 9.066922449 1.639 up 0.0237 RRSL_01626 o c hypothetical Transmembrane protein638721691 10.13112987 9.663922449 1.525 up 0.207 RRSL_01628 o c Hypothetical Protein638721692 8.706129869 9.175547449 1.255 down 0.118 RRSL_01629 o c Transcriptional regulator638721693 8.768429869 9.011647449 1.072 down 0.722 RRSL_01630 o c Hypothetical exported protein638721694 9.637704869 9.896622449 1.084 down 0.517 RRSL_01631 o c ABC transporter ATP-binding protein638721695 9.169579869 10.07219745 1.694 down 0.00615 RRSL_01633 o c ABC transporter permease protein638721698 10.06527987 10.42849745 1.165 down 0.0604 RRSL_01635 o c Hypothetical Protein638721699 8.934004869 9.269897449 1.144 down 0.189 RRSL_01636 o c D-glycero-D-manno-heptose-1-phosphate adenylyltransferase( EC:2.7.7.- )638721700 12.60900487 13.33574745 1.5 down 0.0095 RRSL_01637 o c Hypothetical Protein638721701 8.907154869 8.856872449 1.142 up 0.543 RRSL_01638 o c Glutathione peroxidase( EC:1.11.1.9 )638721702 9.326979869 9.904297449 1.352 down 0.0522 RRSL_01639 o c Serine protease( EC:3.4.21.- )638721703 13.70092987 13.35447245 1.402 up 0.307 RRSL_01640 o c Hypothetical Protein638721704 11.84770487 11.99474745 1.003 down 0.984 RRSL_01641 o c Enoyl-CoA hydratase( EC:4.2.1.17 )638721706 10.43730487 10.17032245 1.327 up 0.322 RRSL_01644 o c Transcriptional regulator, IclR family638721708 8.430829869 8.791072449 1.163 down 0.112 RRSL_01647 o c 3-oxoadipate enol-lactonase( EC:3.1.1.24 )638721709 11.95645487 12.05552245 1.029 up 0.907 RRSL_01648 o c Hypothetical Protein638721710 9.140054869 9.488347449 1.153 down 0.554 RRSL_01649 o c sulfide dehydrogenase precursor638721711 11.23402987 12.20929745 1.782 down 0.00232 RRSL_01650 o c 5-methyltetrahydrofolate--homocysteine methyltransferase homocysteine-binding subunit( EC:2.1.1.13 )638721712 11.21795487 11.80199745 1.358 down 0.00084 RRSL_01651 o c 5-methyltetrahydrofolate--homocysteine methyltransferase cobalamin-binding subunit( EC:2.1.1.13 )638721713 13.47975487 13.51537245 1.076 up 0.754 RRSL_01652 o c Hypothetical Protein638721716 12.81215487 13.34184745 1.308 down 0.0734 RRSL_01655 o c Hypothetical Protein638721717 12.33915487 12.38532245 1.068 up 0.216 RRSL_01656 o c Hypothetical Protein638721718 10.26197987 10.75029745 1.271 down 0.0523 RRSL_01657 o c Sensory transduction protein kinase( EC:2.7.3.- )638721720 12.53200487 13.34307245 1.59 down 0.0166 RRSL_01659 o c Hypothetical Protein638721722 11.49090487 12.46892245 1.785 down 0.000661 RRSL_01661 o c ftsN FtsN638721723 14.56590487 15.58484745 1.836 down 0.00224 RRSL_01662 o c dsbA DsbA638721726 8.821404869 9.652947449 1.613 down 0.0264 RRSL_01665 o c JemB638721727 8.706504869 9.402772449 1.468 down 0.064 RRSL_01666 o c zinc metallohydrolase, glyoxalase ii family638721728 9.289029869 9.488272449 1.04 down 0.878 RRSL_01667 o c probable transcriptional regulator638721729 11.49875487 10.61577245 2.034 up 0.0763 RRSL_01668 o c Isovaleryl-CoA dehydrogenase( EC:1.3.99.10 )638721731 11.44810487 10.88447245 1.63 up 0.0727 RRSL_01670 o c Isocitrate dehydrogenase kinase/phosphatase (IDH kinase/phosphatase)( EC:2.7.1.116,EC:3.1.3.- )638721735 10.32795487 11.15252245 1.605 down 0.0136 RRSL_01532 o c Threonine synthase( EC:4.2.3.1 )638721736 10.17225487 10.23202245 1.058 up 0.778 RRSL_01533 o c Uracil DNA glycosylase superfamily protein638721737 10.88887987 11.20329745 1.127 down 0.324 RRSL_01534 o c Molybdopterin biosynthesis MoeA protein638721738 7.539204869 8.283022449 1.517 down 0.0782 RRSL_01535 o c Molybdopterin converting factor, small subunit638721739 10.91385487 11.27779745 1.166 down 0.0218 RRSL_01536 o c Molybdopterin converting factor, large subunit638721740 10.84307987 10.84334745 1.102 up 0.681 RRSL_01537 o c CrcB family protein638721741 9.241779869 9.793272449 1.328 down 0.18 RRSL_01538 o c hydroxybutyrate-dimer hydrolase( EC:3.1.1.22 )638721751 11.07540487 10.35834745 1.813 up 0.0192 RRSL_01548 o c Hypothetical Protein638721755 9.008929869 8.378772449 1.707 up 0.0398 RRSL_01553 o c Transcriptional regulator cbl638721760 10.02555487 10.15929745 1.005 up 0.96 RRSL_01558 o c Acetolactate synthase large subunit( EC:2.2.1.6 )638721761 8.112479869 8.845547449 1.506 down 0.0344 RRSL_01560 o c Butirosin biosynthesis protein BtrG638721762 8.436479869 7.806822449 1.706 up 0.216 RRSL_01561 o c Leucine-rich repeat family protein638721766 9.401754869 8.853772449 1.612 up 0.00364 RRSL_01565 o c Universal stress protein family638721767 8.591779869 8.873997449 1.102 down 0.218 RRSL_01566 o c Transcriptional regulators, LysR family638721768 10.83277987 10.99577245 1.014 down 0.952 RRSL_01567 o c 2-haloalkanoic acid dehalogenase( EC:3.8.1.2 )638721769 9.983104869 10.82994745 1.63 down 0.00758 RRSL_01568 o c Malate synthase( EC:4.1.3.2 )638721770 11.16370487 11.84104745 1.449 down 0.0256 RRSL_01569 o c Hypothetical Protein638721771 9.008754869 9.575197449 1.342 down 0.0815 RRSL_01570 o c Acyl-CoA-binding protein homolog638721772 11.07440487 10.91619745 1.231 up 0.057 RRSL_01571 o c Hypothetical Protein638721773 8.840279869 9.400247449 1.336 down 0.238 RRSL_01572 o c Ribosomal-protein-S18-alanine acetyltransferase( EC:2.3.1.128 )638721774 10.35300487 10.55682245 1.044 down 0.598 RRSL_01573 o c Uracil DNA glycosylase superfamily protein638721775 11.66997987 11.82999745 1.012 down 0.899 RRSL_01574 o c Transporter638721778 13.46777987 14.07967245 1.385 down 0.382 RRSL_01577 o c Disulfide bond formation protein B638721782 9.516854869 9.046197449 1.528 up 0.0396 RRSL_01583 o c Hypothetical Protein

638721783 7.084004869 7.546672449 1.249 down 0.183 RRSL_01584 o c Iron-sulfur cluster assembly/repair protein ApbE638721784 8.511054869 7.770372449 1.843 up 0.0732 RRSL_01585 o c Hypothetical Protein638721792 10.13497987 10.99019745 1.639 down 0.0645 RRSL_01595 o c Lysine-specific permease638721793 9.961704869 10.40482245 1.232 down 0.201 RRSL_01596 o c Lysine-specific permease

638721794 8.994254869 9.732497449 1.512 down 0.00802 RRSL_01597 o cEnoyl-CoA hydratase / Delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase( EC:1.1.1.35,EC:4.2.1.17,EC:5.1.2.3,EC:5.3.3.8 )

638721795 8.277029869 8.765097449 1.271 down 0.0943 RRSL_01598 o c Pyrazinamidase / Nicotinamidase( EC:3.5.1.-,EC:3.5.1.19 )638721796 9.254504869 9.537547449 1.102 down 0.615 RRSL_01599 o c 3-ketoacyl-CoA thiolase( EC:2.3.1.16 )638721797 8.360579869 8.528147449 1.018 down 0.908 RRSL_01600 o c Acyl-CoA dehydrogenase( EC:1.3.99.- )638721798 8.859054869 8.679772449 1.249 up 0.341 RRSL_01601 o c Short chain dehydrogenase638721799 8.192429869 8.953522449 1.536 down 0.0102 RRSL_01602 o c Hypothetical cytosolic protein638721801 8.146379869 8.332472449 1.031 down 0.91 RRSL_01604 o c 6-aminohexanoate-dimer hydrolase( EC:3.5.1.46 )638721802 9.418829869 10.28829745 1.656 down 0.0112 RRSL_01605 o c Hypothetical Protein638721803 10.20062987 10.70614745 1.286 down 0.0887 RRSL_01606 o c Class II Aldolase and Adducin proteins638721804 9.386229869 9.902522449 1.296 down 0.0977 RRSL_01607 o c Glutathione S-transferase( EC:2.5.1.18 )638721805 9.065954869 9.898547449 1.614 down 0.0297 RRSL_01608 o c Hypothetical Protein638721806 9.952779869 10.55547245 1.376 down 0.0386 RRSL_01609 o c Epoxide hydrolase( EC:3.3.2.3 )638721807 8.302504869 8.246822449 1.146 up 0.164 RRSL_01611 o c 1,3-propanediol dehydrogenase( EC:1.1.1.202 )638721808 12.54687987 10.73382245 3.876 up 0.113 RRSL_01610 o c Acetyl-hydrolase( EC:3.1.1.- )638721809 8.221079869 9.169472449 1.749 down 0.000604 RRSL_01613 o c Acetyltransferase( EC:2.3.1.- )638721811 8.811454869 9.278447449 1.252 down 0.328 RRSL_01615 o c signal peptide638721812 7.593004869 8.559847449 1.771 down 0.0159 RRSL_01616 o c Hypothetical Protein638721813 10.46370487 11.47344745 1.825 down 0.0121 RRSL_01617 o c Aminomethyltransferase homolog638721814 10.22285487 9.069672449 2.453 up 0.166 RRSL_01618 o c Hypothetical protein638721815 10.15990487 10.97969745 1.6 down 0.0203 RRSL_01619 o c Thymidylate kinase( EC:2.7.4.9 )638721816 11.96137987 12.34239745 1.18 down 0.152 RRSL_01620 o c DNA polymerase III, delta subunit( EC:2.7.7.7 )638721817 11.34895487 12.42262245 1.907 down 0.0425 RRSL_02001 o c Hypothetical Protein638721818 10.58125487 11.23017245 1.421 down 0.104 RRSL_02002 o c Nitrogen regulation protein ntrY( EC:2.7.3.- )638721819 9.980879869 10.47669745 1.278 down 0.0468 RRSL_02003 o c probable signal peptide, proline rich protein638721820 11.33977987 9.476347449 4.014 up 0.0689 RRSL_02004 o c 16S rRNA m(5)C 967 methyltransferase( EC:2.1.1.- )638721821 12.05887987 13.01109745 1.753 down 0.0404 RRSL_02005 o c Heat shock protein HtpX638721822 8.911354869 8.607347449 1.361 up 0.0187 RRSL_02006 o c Hypothetical Protein638721823 8.352429869 8.641272449 1.107 down 0.456 RRSL_02007 o c Methionyl-tRNA formyltransferase( EC:2.1.2.9 )638721824 9.948454869 9.910122449 1.132 up 0.467 RRSL_02008 o c Hypothetical Protein638721825 12.05502987 12.46457245 1.204 down 0.0768 RRSL_02009 o c Peptide deformylase( EC:3.5.1.88 )638721827 11.09617987 11.49654745 1.196 down 0.232 RRSL_02011 o c Smf protein638721828 10.68767987 11.17637245 1.271 down 0.0118 RRSL_02012 o c Thiol-disulfide isomerase and thioredoxins638721829 11.57687987 12.31392245 1.51 down 0.0526 RRSL_02013 o c DNA topoisomerase I( EC:5.99.1.2 )638721830 9.299679869 9.326672449 1.082 up 0.649 RRSL_02014 o c Transcriptional regulators, LysR family638721831 10.46055487 11.07869745 1.391 down 0.121 RRSL_02015 o c AMP-(fatty)acid ligases638721832 11.79200487 11.58212245 1.275 up 0.111 RRSL_02016 o c rodA RodA638721833 9.650379869 9.730272449 1.043 up 0.674 RRSL_02017 o c Cell elongation specific D,D-transpeptidase638721834 12.00512987 11.26149745 1.847 up 0.0338 RRSL_02018 o c mreD MreD638721835 10.56670487 10.90857245 1.148 down 0.344 RRSL_02019 o c mreC MreC638721836 12.51050487 12.69097245 1.027 down 0.902 RRSL_02020 o c mreB MreB638721838 11.99947987 12.99324745 1.805 down 0.00885 RRSL_02022 o c Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C( EC:6.3.5.- )638721839 11.48267987 12.22827245 1.519 down 0.00518 RRSL_02023 o c probable Glu-tRNA (Gln) amidotransferase subunit A( EC:6.3.5.- )638721840 9.725629869 10.57609745 1.634 down 0.0337 RRSL_02024 o c Hypothetical Protein638721841 7.378279869 8.300647449 1.717 down 0.039 RRSL_02025 o c Hypothetical Protein638721842 12.41357987 12.97954745 1.341 down 0.0694 RRSL_02026 o c Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B( EC:6.3.5.- )638721843 10.54110487 10.46494745 1.162 up 0.316 RRSL_02028 o c Integrase/recombinase (XerC/CodV family)638721844 9.294429869 9.826797449 1.311 down 0.0357 RRSL_02029 o c Methyltransferase( EC:2.1.1.- )638721846 12.42305487 12.46544745 1.071 up 0.785 RRSL_02031 o c Carboxy-cis,cis-muconate cyclase( EC:5.5.1.5 )638721849 10.43452987 11.54514745 1.957 down 0.0195 RRSL_02033 o c Ferric uptake regulation protein638721850 11.59370487 12.30419745 1.483 down 0.0202 RRSL_02034 o c Low-affinity zinc transport protein638721852 10.43447987 10.83882245 1.199 down 0.34 RRSL_02036 o c Low-affinity zinc transport protein638721853 9.424029869 8.926497449 1.557 up 0.0831 RRSL_02037 o c substrate binding periplasmic protein

638721858 13.01527987 13.58499745 1.345 down 0.19 RRSL_01390 o c N utilization substance protein A638721859 14.90000487 14.79252245 1.188 up 0.135 RRSL_01391 o c Hypothetical cytosolic protein638721860 12.59965487 13.37702245 1.553 down 0.145 RRSL_01392 o c Ribosomal large subunit pseudouridine synthase B( EC:4.2.1.70 )638721861 11.45327987 12.18912245 1.509 down 0.173 RRSL_01393 o c scpB ScpB638721862 10.54675487 9.967997449 1.647 up 0.0394 RRSL_01394 o c Hypothetical Protein638721863 13.52845487 13.23764745 1.349 up 0.0229 RRSL_01395 o c Hypothetical Protein638721864 10.74547987 10.01417245 1.831 up 0.0529 RRSL_01396 o c Hypothetical Protein638721872 8.818779869 8.241197449 1.646 up 0.134 RRSL_01404 o c 2-phosphosulfolactate phosphatase( EC:3.1.3.- )638721873 10.32152987 11.15059745 1.61 down 0.00237 RRSL_01405 o c ATPase638721877 7.777604869 8.296722449 1.299 down 0.224 RRSL_01409 o c Glycerophosphoryl diester phosphodiesterase( EC:3.1.4.46 )638721878 9.552904869 9.462447449 1.174 up 0.141 RRSL_01410 o c ugpC UgpC638721879 9.832754869 9.037272449 1.914 up 0.142 RRSL_01411 o c ugpE UgpE638721880 8.881704869 8.337597449 1.608 up 0.238 RRSL_01412 o c ugpA UgpA638721883 10.38255487 10.33579745 1.139 up 0.432 RRSL_01415 o c Glycerol-3-phosphate-binding protein638721884 9.470879869 9.209697449 1.322 up 0.15 RRSL_01416 o c Hydrolase (HAD superfamily)638721886 10.82620487 11.43477245 1.382 down 0.0536 RRSL_01418 o c Nitrogen regulation protein NR(I)638721887 10.65805487 11.02282245 1.167 down 0.0186 RRSL_01419 o c Nitrogen regulation protein ntrB( EC:2.7.3.- )638721888 13.10982987 13.75782245 1.42 down 0.113 RRSL_01420 o c Hypothetical Protein638721891 11.17637987 11.42184745 1.074 down 0.759 RRSL_01423 o c Putative competence-damage protein638721892 11.14067987 11.31847245 1.025 down 0.755 RRSL_01424 o c Hypothetical Protein638721893 11.05742987 10.65534745 1.457 up 0.00555 RRSL_01425 o c C-5 sterol desaturase( EC:1.3.- )638721894 10.60805487 11.40037245 1.569 down 0.0429 RRSL_01426 o c Hypothetical Protein638721895 12.81950487 13.18942245 1.171 down 0.173 RRSL_01427 o c PGRS-subfamily of Gly-rich proteins638721896 9.664004869 10.09262245 1.22 down 0.0351 RRSL_01428 o c hrpA HrpA638721897 15.11252987 14.94319745 1.24 up 0.118 RRSL_01355 o c xpsR XpsR638721898 15.01470487 15.04447245 1.08 up 0.674 RRSL_01356 o c tek Tek638721900 13.84110487 13.44507245 1.451 up 0.111 RRSL_01358 o c tek2 Tek2638721930 11.40327987 11.56472245 1.013 down 0.957 RRSL_01965 o c dppB DppB638721931 9.549579869 9.947522449 1.194 down 0.272 RRSL_01966 o c dppC DppC638721932 8.357129869 9.195622449 1.62 down 0.00505 RRSL_01967 o c dppD DppD638721933 9.715279869 9.842422449 1.01 up 0.937 RRSL_01968 o c hypothetical protein638721939 9.653179869 10.34714745 1.466 down 0.354 RRSL_01975 o c Transcriptional regulatory protein638721943 10.90312987 10.03924745 2.007 up 0.168 RRSL_01979 o c Transporter, MFS superfamily638721944 11.13155487 10.25122245 2.03 up 0.151 RRSL_01980 o c Outer membrane porin protein 32 precursor638721946 10.87897987 11.16942245 1.108 down 0.341 RRSL_01982 o c 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase( EC:1.14.13.- )638721947 12.07885487 13.00162245 1.718 down 0.00953 RRSL_01983 o c mraZ MraZ638721948 12.58735487 12.87462245 1.106 down 0.38 RRSL_01984 o c S-adenosyl-methyltransferase mraW( EC:2.1.1.- )638721949 11.09750487 11.45572245 1.161 down 0.372 RRSL_01985 o c hypothetical protein638721950 10.30767987 10.95929745 1.423 down 0.0373 RRSL_01986 o c Division specific D,D-transpeptidase / Cell division protein ftsI638721951 10.22802987 10.76614745 1.316 down 0.0128 RRSL_01987 o c UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase( EC:6.3.2.13 )

638721952 11.85677987 12.30329745 1.235 down 0.204 RRSL_01988 o c UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase( EC:6.3.2.15 )638721953 12.07137987 12.61359745 1.319 down 0.115 RRSL_01989 o c Phospho-N-acetylmuramoyl-pentapeptide- transferase( EC:2.7.8.13 )638721955 13.46560487 13.07157245 1.449 up 0.227 RRSL_01991 o c ftsW FtsW

638721956 9.872604869 10.39202245 1.299 down 0.039 RRSL_01992 o cUDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase( EC:2.4.1.227 )

638721957 11.97377987 12.55509745 1.356 down 0.0595 RRSL_01993 o c UDP-N-acetylmuramate--alanine ligase( EC:6.3.2.8 )638721958 10.06170487 10.98009745 1.713 down 0.0163 RRSL_01994 o c D-alanine--D-alanine ligase( EC:6.3.2.4 )638721959 11.37325487 11.73672245 1.166 down 0.239 RRSL_01995 o c ftsQ FtsQ638721960 14.53317987 14.58084745 1.067 up 0.406 RRSL_01996 o c ftsA FtsA638721961 13.97350487 14.59444745 1.394 down 0.266 RRSL_01997 o c ftsZ FtsZ638721963 11.83860487 11.95454745 1.018 up 0.86 RRSL_01999 o c Probable peroxiredoxin638721964 10.28987987 10.92199745 1.404 down 0.0117 RRSL_02000 o c UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase( EC:3.5.1.- )638721966 8.062679869 8.496097449 1.224 down 0.376 RRSL_01116 o c Assimilatory nitrate reductase catalytic subunit( EC:1.7.1.2 )638721995 14.57182987 15.22764745 1.428 down 0.0307 RRSL_01323 o c SSU ribosomal protein S2P638721996 11.65122987 12.41772245 1.541 down 0.113 RRSL_01324 o c Methionine aminopeptidase( EC:3.4.11.18 )638721997 9.085504869 9.893722449 1.587 down 0.0165 RRSL_01325 o c [protein-PII] uridylyltransferase( EC:2.7.7.59 )

638721998 9.595879869 10.39224745 1.574 down 0.0942 RRSL_01326 o c Ribosomal large subunit pseudouridine synthase F( EC:4.2.1.70 )638721999 10.15930487 9.998372449 1.233 up 0.337 RRSL_01327 o c Hypothetical Protein638722000 9.771854869 10.07277245 1.116 down 0.499 RRSL_01329 o c NAD-dependent DNA ligase( EC:6.5.1.2 )638722001 10.50040487 11.16132245 1.433 down 0.0327 RRSL_01330 o c zipA ZipA638722003 9.869479869 10.28557245 1.209 down 0.426 RRSL_01332 o c 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase( EC:3.7.1.- )638722004 9.040354869 9.031472449 1.11 up 0.696 RRSL_01333 o c rarD RarD638722007 11.53362987 12.25267245 1.492 down 0.0278 RRSL_01337 o c Hypothetical Protein638722008 10.34445487 11.27824745 1.731 down 0.00155 RRSL_01338 o c Succinyl-diaminopimelate desuccinylase( EC:3.5.1.18 )638722009 10.26777987 11.22022245 1.754 down 0.000708 RRSL_01340 o c Ribosomal protein L3P methyltransferase( EC:2.1.1.- )638722017 10.63180487 11.98537245 2.316 down 0.0875 RRSL_01348 o c dppB DppB638722022 9.593804869 10.26729745 1.445 down 0.0216 RRSL_01353 o c ABC transporter ATP-binding protein638722034 13.92662987 14.15472245 1.061 down 0.678 RRSL_01057 o c epsF EpsF638722035 13.25255487 13.97637245 1.497 down 0.128 RRSL_01058 o c epsE EpsE638722036 14.16152987 14.86954745 1.48 down 0.145 RRSL_01059 o c espD EspD( EC:1.1.1.- )638722037 14.99130487 15.29724745 1.12 down 0.167 RRSL_01060 o c epsC EpsC( EC:5.1.3.14 )638722038 14.23257987 14.91699745 1.456 down 0.145 RRSL_01061 o c epsB EpsB638722040 15.48220487 15.82769745 1.151 down 0.253 RRSL_01063 o c epsA EpsA638722058 9.152279869 9.813197449 1.433 down 0.0962 RRSL_01255 o c XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase)638722060 8.900029869 9.490797449 1.365 down 0.0265 RRSL_01257 o c Guanine deaminase( EC:3.5.4.3 )638722061 8.490379869 8.949947449 1.246 down 0.054 RRSL_01258 o c Integral membrane protein638722062 8.140429869 7.247897449 2.048 up 0.0699 RRSL_01260 o c Hypothetical Protein638722069 8.456454869 9.285347449 1.61 down 0.00131 RRSL_01267 o c Hypothetical membrane spanning protein638722070 9.428004869 9.857022449 1.22 down 0.292 RRSL_01268 o c Urate oxidase( EC:1.7.3.3 )638722071 13.67007987 13.23964745 1.486 up 0.183 RRSL_01269 o c Transcriptional regulator, GntR family638722074 8.731829869 8.916122449 1.029 down 0.902 RRSL_01272 o c Chitooligosaccharide deacetylase( EC:3.5.1.- )638722075 9.222129869 9.608722449 1.185 down 0.278 RRSL_01273 o c Conserved Hypothetical Protein638722079 10.93980487 11.61104745 1.443 down 0.0197 RRSL_01278 o c Hypothetical Protein638722084 10.76420487 10.56317245 1.268 up 0.0308 RRSL_01282 o c Poly(3-hydroxyalkanoate) depolymerase( EC:3.1.1.- )638722086 9.654929869 10.27332245 1.391 down 0.173 RRSL_01284 o c Hypothetical Protein638722087 11.67362987 11.78287245 1.022 up 0.863 RRSL_01285 o c greB GreB638722100 10.90565487 11.41034745 1.286 down 0.0704 RRSL_01026 o c pehC PehC( EC:3.2.1.15 )638722103 9.158879869 8.754447449 1.46 up 0.00642 RRSL_01029 o c D-galactarate dehydratase( EC:4.2.1.42 )638722128 11.35292987 12.02637245 1.445 down 0.0348 RRSL_01213 o c Serine protease( EC:3.4.21.- )638722129 13.08407987 14.17427245 1.929 down 0.000098 RRSL_01214 o c Hypothetical cytosolic protein638722131 11.49305487 12.50694745 1.83 down 0.0362 RRSL_01216 o c Ornithine carbamoyltransferase( EC:2.1.3.3 )638722132 11.88322987 11.86384745 1.118 up 0.481 RRSL_01217 o c PhnO protein638722134 11.04225487 11.68604745 1.416 down 0.0308 RRSL_01219 o c Virulence factor mviN homolog638722135 11.58665487 12.31439745 1.501 down 0.0068 RRSL_01220 o c Transcriptional regulator638722136 11.80280487 12.76139745 1.761 down 0.00619 RRSL_01221 o c DedA family protein638722137 12.05182987 12.90099745 1.632 down 0.00592 RRSL_01222 o c Transcriptional regulator, TetR family638722138 9.670779869 9.035872449 1.713 up 0.183 RRSL_01223 o c Hypothetical Protein638722139 7.792654869 7.828897449 1.075 up 0.83 RRSL_01224 o c Paraquat-inducible protein B638722140 9.163829869 9.980897449 1.597 down 0.0323 RRSL_01225 o c mutL MutL638722141 9.852704869 10.51907245 1.438 down 0.0602 RRSL_01226 o c tRNA delta(2)-isopentenylpyrophosphate transferase( EC:2.5.1.8 )638722142 8.131829869 8.724447449 1.366 down 0.166 RRSL_01227 o c Diamine acetyltransferase( EC:2.3.1.57 )638722143 9.310379869 9.499972449 1.033 down 0.86 RRSL_01228 o c Hypothetical Protein638722144 9.101654869 8.526097449 1.644 up 0.0593 RRSL_01229 o c AlkB protein638722145 9.560579869 9.666572449 1.025 up 0.878 RRSL_01230 o c alkB AlkB638722146 8.127304869 8.264347449 1.003 up 0.993 RRSL_01231 o c DNA-3-methyladenine glycosylase II( EC:3.2.2.21 )

638722147 7.414729869 7.806247449 1.189 down 0.491 RRSL_01233 o cProbable ADA regulatory protein of adaptive response / O6-methylguanine-DNA methyltransferase( EC:2.1.1.63 )

638722148 9.114504869 10.11884745 1.818 down 0.00424 RRSL_01234 o c Hypothetical Protein638722150 11.68495487 11.92979745 1.074 down 0.782 RRSL_01236 o c Hypothetical Protein638722152 12.05300487 12.99219745 1.738 down 0.0123 RRSL_01238 o c Phosphoserine phosphatase( EC:3.1.3.3 )638722154 10.22952987 11.08959745 1.645 down 0.0386 RRSL_01240 o c 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase( EC:2.7.6.3 )638722155 9.296854869 10.18352245 1.675 down 0.0209 RRSL_01241 o c Deoxyguanosine kinase( EC:2.7.1.113 )638722156 11.42397987 12.17277245 1.523 down 0.0147 RRSL_01242 o c 3-methyl-2-oxobutanoate hydroxymethyltransferase( EC:2.1.2.11 )

638722157 10.72955487 11.11552245 1.184 down 0.585 RRSL_01243 o c Hypothetical Protein638722158 8.634279869 9.468147449 1.615 down 0.00737 RRSL_01244 o c Transporter638722159 8.504929869 9.119097449 1.387 down 0.0259 RRSL_01245 o c Para-aminobenzoate synthetase component I /4-amino-4-deoxychorismate lyase( EC:4.-,EC:4.1.3.- )638722164 11.40550487 11.54137245 1.004 up 0.983 RRSL_01492 o c Hypothetical Protein638722165 9.740329869 10.07002245 1.139 down 0.45 RRSL_01493 o c ABC type uncharacterized transport system permease component638722166 11.65507987 10.86059745 1.913 up 0.000675 RRSL_01495 o c Hypothetical Protein638722168 13.36850487 13.98519745 1.389 down 0.0453 RRSL_01497 o c Hypothetical Protein638722169 12.69107987 13.66227245 1.777 down 0.0597 RRSL_01498 o c ElaB protein638722170 14.13040487 13.98269745 1.222 up 0.196 RRSL_01499 o c Peroxiredoxin( EC:1.11.1.7 )638722171 8.132129869 7.770022449 1.417 up 0.278 RRSL_01500 o c Guanine-hypoxanthine permease638722173 8.030629869 8.380972449 1.155 down 0.237 RRSL_01502 o c Glutaryl-CoA dehydrogenase( EC:1.3.99.7 )638722174 7.708304869 7.649722449 1.148 up 0.503 RRSL_01503 o c Transcriptional regulator, IclR family638722177 11.20575487 7.931447449 10.673 up 0.0725 RRSL_01507 o c Metal-dependent hydrolase638722178 9.909504869 8.747372449 2.468 up 0.104 RRSL_01506 o c Hypothetical Protein638722180 10.51650487 10.64172245 1.011 up 0.97 RRSL_01509 o c FMN reductase( EC:1.5.1.29 )638722181 10.76432987 10.51482245 1.311 up 0.0651 RRSL_01510 o c Peptide methionine sulfoxide reductase msrA( EC:1.8.4.6 )638722182 9.226379869 9.238197449 1.094 up 0.491 RRSL_01511 o c Hypothetical Protein638722183 12.78145487 12.66802245 1.193 up 0.242 RRSL_01512 o c Cyclopropane-fatty-acyl-phospholipid synthase( EC:2.1.1.79 )638722190 9.523929869 10.61399745 1.929 down 0.00287 RRSL_01519 o c probable transmembrane638722191 8.771779869 9.666047449 1.684 down 0.0333 RRSL_01520 o c Molybdopterin biosynthesis MoeB protein638722192 11.08832987 11.52369745 1.225 down 0.284 RRSL_01521 o c peroxidase / catalase( EC:1.11.1.6,EC:1.11.1.7 )638722194 9.249104869 9.987697449 1.512 down 0.0185 RRSL_01523 o c Thioredoxin638722195 12.50860487 11.99322245 1.576 up 0.501 RRSL_01524 o c Thioredoxin638722196 10.51152987 8.681772449 3.921 up 0.073 RRSL_01525 o c Long-chain-fatty-acid--CoA ligase( EC:6.2.1.3 )638722197 9.719204869 9.328972449 1.445 up 0.0774 RRSL_01526 o c ankyrin repeat harboring protein638722198 11.04695487 11.04079745 1.107 up 0.279 RRSL_01527 o c chaC ChaC638722200 11.47620487 12.21217245 1.509 down 0.0108 RRSL_01528 o c Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638722201 11.41285487 12.49154745 1.914 down 0.00168 RRSL_01529 o c Cellulose synthase operon C protein638722205 8.397304869 8.362147449 1.13 up 0.536 RRSL_01288 o c livF LivF638722206 9.027179869 9.116647449 1.036 up 0.747 RRSL_01289 o c livG LivG638722207 10.06550487 10.14617245 1.043 up 0.677 RRSL_01290 o c livM LivM638722208 9.898104869 8.834097449 2.306 up 0.0505 RRSL_01291 o c livH LivH638722210 9.964279869 10.04284745 1.044 up 0.522 RRSL_01293 o c Medium-chain-fatty-acid--CoA ligase( EC:6.2.1.- )638722211 9.205354869 10.06407245 1.643 down 0.0266 RRSL_01294 o c Hypothetical cytosolic protein638722212 11.07367987 11.88839745 1.594 down 0.00266 RRSL_01295 o c Peptide methionine sulfoxide reductase msrB( EC:1.8.4.6 )638722213 12.88217987 13.57249745 1.462 down 0.00305 RRSL_01296 o c Intracellular septation protein638722214 15.03452987 16.03972245 1.819 down 0.0235 RRSL_01297 o c Signal Peptide isomerase rotamase638722215 9.481329869 10.29344745 1.591 down 0.0468 RRSL_01298 o c ABC transporter substrate-binding protein638722216 9.531279869 10.57924745 1.874 down 0.0089 RRSL_01299 o c Hypothetical Protein638722217 9.199454869 10.09057245 1.681 down 0.00218 RRSL_01300 o c ABC transporter ATP-binding protein638722218 9.002879869 9.566322449 1.339 down 0.422 RRSL_01301 o c Outer membrane porin protein 32 precursor638722219 8.392079869 8.231422449 1.233 up 0.0844 RRSL_01302 o c Two component system histidine kinase( EC:2.7.3.- )638722223 9.176304869 8.286922449 2.043 up 0.0686 RRSL_01308 o c Short-chain type dehydrogenase/reductase( EC:1.- )638722225 13.34257987 12.78504745 1.623 up 0.141 RRSL_01310 o c Hypothetical Protein638722226 16.73212987 16.31269745 1.475 up 0.00264 RRSL_01311 o c Hypothetical Protein638722229 11.56270487 12.53824745 1.782 down 0.0817 RRSL_01314 o c Phosphoribosylformylglycinamidine synthase( EC:6.3.5.3 )638722230 12.13120487 12.57307245 1.231 down 0.0574 RRSL_01316 o c Hypothetical protein638722231 7.801729869 8.718022449 1.71 down 0.00302 RRSL_01315 o c Nitric-oxide reductase subunit C( EC:1.7.99.7 )638722232 9.783929869 10.72409745 1.739 down 0.0429 RRSL_01317 o c Glucose-6-phosphate isomerase / Glucose-6 phosphate 1-epimerase( EC:5.1.3.15,EC:5.3.1.9 )638722234 9.040854869 9.575322449 1.312 down 0.0886 RRSL_01318 o c Acyl-CoA thioesterase I / Lysophospholipase( EC:3.1.1.5,EC:3.1.2.- )638722236 9.166429869 10.02872245 1.647 down 0.00782 RRSL_01450 o c Exodeoxyribonuclease VII large subunit( EC:3.1.11.6 )638722239 9.000554869 8.777397449 1.287 up 0.359 RRSL_01453 o c Hypothetical Protein638722240 9.832654869 9.867872449 1.076 up 0.446 RRSL_01454 o c Hypothetical cytosolic protein638722243 8.855979869 9.073047449 1.053 down 0.598 RRSL_01457 o c hypothetical protein638722244 10.05852987 9.697522449 1.416 up 0.151 RRSL_01458 o c D-beta-hydroxybutyrate permease638722246 9.683654869 9.790822449 1.024 up 0.942 RRSL_01460 o c possible transmembrane conserved hypothetical protein638722247 7.885304869 7.530722449 1.41 up 0.0159 RRSL_01461 o c Transporter

638722249 13.37665487 14.13137245 1.529 down 0.204 RRSL_01463 o c Hypothetical Protein638722250 9.628679869 9.580222449 1.14 up 0.142 RRSL_01464 o c Hypothetical Protein638722251 10.16712987 10.72949745 1.338 down 0.0148 RRSL_01465 o c Cyclohexadienyl dehydratase precursor( EC:4.2.1.51 )638722252 12.33382987 12.33014745 1.106 up 0.325 RRSL_01466 o c C4-dicarboxylate-binding protein638722253 15.52472987 15.69572245 1.02 down 0.724 RRSL_01467 o c Hypothetical Protein638722255 10.36705487 9.867972449 1.559 up 0.209 RRSL_01469 o c Transporter, drug/metabolite exporter family638722257 7.883004869 7.467072449 1.471 up 0.18 RRSL_01471 o c ADA regulatory protein / O6-methylguanine-DNA methyltransferase( EC:2.1.1.63 )638722259 8.466729869 8.779322449 1.125 down 0.602 RRSL_01473 o c Hypothetical Protein638722260 12.34645487 11.68834745 1.74 up 0.128 RRSL_01474 o c Neutral zinc metallopeptidase family638722263 8.611379869 8.897772449 1.105 down 0.441 RRSL_01477 o c putative gamma-glutamyltranspeptidase( EC:2.3.2.2 )638722267 9.344754869 9.342997449 1.104 up 0.677 RRSL_01479 o c Transcriptional regulators, LysR family638722268 8.331654869 9.003797449 1.444 down 0.0476 RRSL_01481 o c Transcriptional regulators, LysR family638722270 11.02535487 11.98502245 1.762 down 0.00177 RRSL_01483 o c Metal-dependent hydrolase( EC:3.- )638722271 8.088204869 8.984247449 1.686 down 0.00795 RRSL_01485 o c Calcineurin-like phosphoesterase638722272 16.68672987 16.94019745 1.08 down 0.0665 RRSL_01486 o c hypothetical signal peptide protein638722274 10.75227987 11.61104745 1.643 down 0.00692 RRSL_01080 o c Arogenate dehydrogenase / Prephenate dehydrogenase( EC:1.3.1.12,EC:1.3.1.43 )638722275 8.565579869 9.506322449 1.739 down 0.0363 RRSL_01081 o c Hypothetical Protein638722276 12.31700487 12.75394745 1.227 down 0.175 RRSL_01082 o c chorismate mutase / prephenate dehydratase( EC:4.2.1.51,EC:5.4.99.5 )638722277 11.45495487 12.35677245 1.693 down 0.0645 RRSL_01083 o c Phosphoserine aminotransferase( EC:2.6.1.52 )638722278 15.29735487 15.96889745 1.443 down 0.0111 RRSL_01084 o c Hypothetical Protein638722279 14.17635487 14.73467245 1.334 down 0.0386 RRSL_01085 o c DNA gyrase subunit A( EC:5.99.1.3 )638722280 16.48452987 16.78444745 1.115 down 0.14 RRSL_01086 o c Outer membrane protein638722281 13.69162987 13.78564745 1.033 up 0.891 RRSL_01087 o c Hypothetical Protein638722282 11.93317987 12.97904745 1.871 down 0.0071 RRSL_01088 o c 3-demethylubiquinone 3-methyltransferase( EC:2.1.1.64 )638722283 10.14850487 10.42902245 1.101 down 0.417 RRSL_01090 o c probable transmembrane638722292 8.754879869 9.486997449 1.505 down 0.155 RRSL_01100 o c UDP-N-acetylenolpyruvoylglucosamine reductase( EC:1.1.1.158 )638722293 11.36560487 12.23719745 1.658 down 0.02 RRSL_01101 o c yajQ YajQ638722294 12.15712987 12.74679745 1.364 down 0.0516 RRSL_01102 o c Hypothetical membrane spanning protein638722295 8.636829869 8.850597449 1.051 down 0.798 RRSL_01103 o c Regulatory protein638722296 8.848929869 9.723422449 1.661 down 0.0149 RRSL_01104 o c Integrase/recombinase (XerD/RipX family)638722297 10.61490487 10.53269745 1.167 up 0.202 RRSL_01106 o c Hypothetical Protein638722298 10.03995487 10.23244745 1.035 down 0.86 RRSL_01109 o c iron-sulfur cluster-binding protein638722300 8.858729869 8.718997449 1.215 up 0.178 RRSL_01111 o c Transporter, Sodium/bile acid symporter family638722301 8.097479869 8.180972449 1.041 up 0.833 RRSL_01112 o c Transcriptional regulatory protein638722321 8.754854869 9.756472449 1.814 down 0.038 RRSL_00938 o c mexD MexD638722322 7.715429869 8.811597449 1.937 down 0.000843 RRSL_00939 o c Type I secretion outer membrane protein638722334 16.01627987 15.42429745 1.662 up 0.00123 RRSL_00810 o c Cold shock protein638722337 7.923629869 8.563997449 1.412 down 0.0544 RRSL_00813 o c FdhD protein (fdsC)638722369 9.232779869 10.19312245 1.763 down 0.0889 RRSL_00961 o c Hypothetical Protein638722370 11.71472987 12.18644745 1.257 down 0.285 RRSL_00962 o c Outer-membrane lipoproteins carrier protein638722371 9.476679869 9.999197449 1.302 down 0.134 RRSL_00963 o c ftsK FtsK638722372 11.80452987 12.93787245 1.988 down 0.00132 RRSL_00964 o c Thioredoxin reductase( EC:1.8.1.9 )638722373 10.22027987 10.68554745 1.251 down 0.0465 RRSL_00965 o c SMR/MUTS family protein638722374 11.30217987 11.63669745 1.142 down 0.127 RRSL_00966 o c Hypothetical Protein638722375 13.03122987 13.18454745 1.008 down 0.95 RRSL_00967 o c Hypothetical Protein638722376 12.87827987 12.71302245 1.237 up 0.202 RRSL_00968 o c Hypothetical Protein638722377 12.24535487 12.12649745 1.197 up 0.0238 RRSL_00969 o c Glutamine-dependent NAD(+) synthetase( EC:6.3.5.1 )638722380 10.37265487 10.75947245 1.185 down 0.14 RRSL_00972 o c Aldehyde dehydrogenase( EC:1.2.1.3 )638722381 8.952554869 9.072222449 1.015 up 0.906 RRSL_00973 o c Hypothetical Protein638722384 10.08530487 10.54419745 1.245 down 0.0823 RRSL_00976 o c HemY protein638722399 7.926379869 7.293397449 1.71 up 0.0254 RRSL_00777 o c Galactarate/altronate dehydratase family protein638722401 9.393804869 10.07724745 1.455 down 0.0299 RRSL_00779 o c 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase( EC:4.1.2.-,EC:4.1.2.20 )638722402 9.172954869 8.897372449 1.335 up 0.0254 RRSL_00780 o c Tartrate dehydrogenase( EC:1.1.1.93 )638722403 8.198804869 8.454572449 1.082 down 0.63 RRSL_00781 o c Succinate-semialdehyde dehydrogenase (NADP+)( EC:1.2.1.16 )638722411 10.94215487 10.46074745 1.54 up 0.00513 RRSL_00683 o c Hypothetical Protein638722412 10.32525487 10.55577245 1.063 down 0.595 RRSL_00684 o c Aldehyde dehydrogenase( EC:1.2.1.3 )638722413 9.437504869 9.994572449 1.333 down 0.101 RRSL_00685 o c Hypothetical Protein

638722414 8.346954869 8.176472449 1.241 up 0.21 RRSL_00686 o c Glucoamylase( EC:3.2.1.3 )638722415 10.10267987 10.42162245 1.13 down 0.454 RRSL_00687 o c Hypothetical protein638722420 8.156254869 7.684397449 1.53 up 0.031 RRSL_00693 o c CoxE protein638722422 8.004229869 7.329422449 1.761 up 0.0118 RRSL_00695 o c Carbon monoxide oxygenase (cytochrome b-561) medium subunit( EC:1.2.2.4 )638722427 10.62402987 10.77824745 1.008 down 0.931 RRSL_00700 o c CreA protein638722428 8.283354869 9.323922449 1.864 down 0.0183 RRSL_00701 o c Transcriptional regulators, LysR family638722429 9.624479869 8.837247449 1.903 up 0.122 RRSL_00702 o c Probable transmembrane multi-drug resistance -like protein, MFS family638722461 11.49960487 10.97754745 1.584 up 0.121 RRSL_00912 o c Transglycosylase associated protein638722462 11.41580487 10.86049745 1.621 up 0.024 RRSL_00913 o c Transcriptional regulatory protein638722463 8.462079869 8.913947449 1.239 down 0.056 RRSL_00915 o c Phosphate regulon sensor protein phoR( EC:2.7.3.- )638722464 9.947529869 10.61857245 1.443 down 0.188 RRSL_00916 o c Hypothetical Protein638722465 13.34420487 13.64862245 1.119 down 0.507 RRSL_00917 o c Transcriptional regulatory protein638722481 10.10782987 10.57017245 1.248 down 0.237 RRSL_01436 o c Phosphatidylserine decarboxylase( EC:4.1.1.65 )638722482 8.937779869 9.301197449 1.166 down 0.392 RRSL_01437 o c Nitropropane dioxygenase / Trans-enoyl-CoA reductase family638722483 8.610204869 8.847997449 1.068 down 0.433 RRSL_01438 o c Haloacetate dehalogenase H-1( EC:3.8.1.3 )638722486 7.121279869 8.015897449 1.685 down 0.0838 RRSL_01441 o c Hypothetical Protein638722487 8.028929869 8.704097449 1.447 down 0.115 RRSL_01442 o c Hypothetical Protein638722488 9.090954869 9.876772449 1.562 down 0.101 RRSL_01443 o c Hydroxymethylglutaryl-CoA lyase( EC:4.1.3.4 )638722489 8.780154869 9.695822449 1.709 down 0.0106 RRSL_01444 o c Putative 2-hydroxyacid dehydrogenase638722492 10.67067987 10.67749745 1.097 up 0.633 RRSL_01447 o c Methylcrotonyl-CoA carboxylase biotin-containing subunit( EC:6.4.1.4 )638722493 7.591229869 7.438397449 1.226 up 0.104 RRSL_01448 o c Sensor protein kdpD( EC:2.7.3.- )638722495 16.63155487 16.85884745 1.061 down 0.0582 RRSL_00979 o c LSU ribosomal protein L13P638722496 16.01260487 16.46817245 1.243 down 0.0177 RRSL_00980 o c SSU ribosomal protein S9P638722497 11.22055487 11.50089745 1.1 down 0.186 RRSL_00981 o c Hypothetical Protein638722498 12.98935487 13.17242245 1.029 down 0.787 RRSL_00982 o c Hypothetical cytosolic protein638722499 13.22222987 13.47997245 1.083 down 0.499 RRSL_00983 o c HesB protein family638722500 11.47035487 11.82627245 1.16 down 0.261 RRSL_00984 o c Hypothetical protein638722501 11.70590487 12.13412245 1.219 down 0.00858 RRSL_00985 o c Tyrosyl-tRNA synthetase tyrS( EC:6.1.1.1 )638722504 10.32015487 11.31629745 1.808 down 0.00259 RRSL_00990 o c ruvB RuvB638722505 9.901354869 10.91812245 1.834 down 0.00629 RRSL_00991 o c ruvA RuvA638722506 11.13105487 10.54882245 1.651 up 0.154 RRSL_00992 o c Glycerophosphoryl diester phosphodiesterase( EC:3.1.4.46 )638722507 10.27747987 10.48992245 1.05 down 0.776 RRSL_00993 o c Crossover junction endodeoxyribonuclease ruvC( EC:3.1.22.4 )638722509 10.90847987 11.45754745 1.326 down 0.0403 RRSL_00995 o c fis Fis638722510 11.46545487 12.39759745 1.729 down 0.0149 RRSL_00996 o c tRNA-dihydrouridine synthase638722514 8.555229869 9.546897449 1.802 down 0.0516 RRSL_01000 o c 2-polyprenyl-6-methoxyphenol hydroxylase( EC:1.14.13.- )638722515 9.995329869 10.73784745 1.516 down 0.00361 RRSL_01001 o c Xaa-Pro aminopeptidase( EC:3.4.11.9 )638722516 8.839954869 8.955947449 1.017 up 0.928 RRSL_01002 o c Hypothetical Protein638722517 9.777204869 10.24179745 1.25 down 0.0829 RRSL_01003 o c Mannose-1-phosphate guanyltransferase( EC:2.7.7.13 )638722518 9.739254869 10.22239745 1.267 down 0.035 RRSL_01004 o c azlD AzlD638722519 11.05237987 11.85757245 1.583 down 0.0168 RRSL_01005 o c Organic solvent tolerance protein638722522 10.41597987 11.05484745 1.411 down 0.0439 RRSL_01009 o c Dimethyladenosine transferase( EC:2.1.1.- )638722523 8.222429869 9.026272449 1.582 down 0.022 RRSL_01010 o c Transporter, drug/metabolite exporter family638722524 12.20167987 13.16822245 1.771 down 0.00126 RRSL_01011 o c Lactoylglutathione lyase( EC:4.4.1.5 )638722527 15.54917987 16.09092245 1.319 down 0.0249 RRSL_00867 o c SSU ribosomal protein S12P638722529 8.569629869 9.338922449 1.544 down 0.0286 RRSL_00869 o c Methyltransferase( EC:2.1.1.- )638722530 8.479804869 9.317772449 1.62 down 0.0154 RRSL_00870 o c Hypothetical Protein638722531 12.50905487 12.69917245 1.034 down 0.887 RRSL_00871 o c Hypothetical Protein638722533 7.668779869 8.485822449 1.596 down 0.0322 RRSL_00873 o c signal peptide638722534 10.86062987 10.76109745 1.181 up 0.672 RRSL_00874 o c Conserved Hypothetical Protein638722537 13.38842987 14.27039745 1.67 down 0.0936 RRSL_00877 o c DNA-directed RNA polymerase beta chain( EC:2.7.7.6 )638722538 15.51187987 16.02257245 1.291 down 0.078 RRSL_00878 o c LSU ribosomal protein L12P (L7/L12)638722539 16.49875487 16.85824745 1.162 down 0.103 RRSL_00879 o c LSU ribosomal protein L10P638722541 14.51055487 15.28467245 1.55 down 0.0735 RRSL_00881 o c LSU ribosomal protein L1P638722542 13.62202987 14.81369745 2.07 down 0.063 RRSL_00882 o c LSU ribosomal protein L11P638722543 14.63000487 14.79907245 1.019 down 0.929 RRSL_00883 o c nusG NusG638722544 14.74465487 15.21424745 1.255 down 0.192 RRSL_00884 o c Protein translocase subunit secE638722553 12.20042987 13.00964745 1.588 down 0.108 RRSL_00659 o c Formyltetrahydrofolate deformylase( EC:3.5.1.10 )

638722554 9.325829869 10.42854745 1.946 down 0.024 RRSL_00660 o c Thiamin pyrophosphokinase( EC:2.7.6.2 )638722555 13.01252987 13.46782245 1.242 down 0.22 RRSL_00661 o c Hypothetical Protein638722556 12.40847987 12.64992245 1.071 down 0.837 RRSL_00662 o c Hypothetical Protein638722557 12.35567987 12.65212245 1.113 down 0.719 RRSL_00663 o c lipid A-myristate beta-hydroxylase( EC:1.14.11.- )638722559 10.19220487 10.25724745 1.054 up 0.534 RRSL_00665 o c Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638722560 9.055204869 9.503897449 1.237 down 0.0796 RRSL_00666 o c syrB SyrB638722561 7.999004869 8.173472449 1.022 down 0.873 RRSL_00667 o c Thioredoxin reductase( EC:1.6.4.5 )638722563 8.677929869 8.089422449 1.658 up 0.0615 RRSL_00669 o c dppC DppC638722564 7.346729869 7.823622449 1.261 down 0.0931 RRSL_00670 o c dppD DppD638722565 8.553504869 8.210272449 1.399 up 0.173 RRSL_00671 o c dppF DppF638722566 10.49897987 10.50139745 1.101 up 0.681 RRSL_00672 o c Dipeptide-binding protein638722567 8.833354869 8.847097449 1.092 up 0.568 RRSL_00673 o c Hypothetical Protein638722568 7.928504869 7.974197449 1.068 up 0.729 RRSL_00674 o c Hypothetical Protein

638722569 7.622854869 7.890097449 1.09 down 0.429 RRSL_00675 o cOxidoreductase transmembrane probable isoquinolone 1-oxidoreductase (Beta-subunit) (E.C.1.3.99.16) (iorB2)

638722570 8.428729869 8.573397449 1.002 down 0.993 RRSL_00676 o c Membrane-bound aldehyde dehydrogenase iron-sulfur protein( EC:1.2.99.3 )638722571 8.233254869 8.559572449 1.136 down 0.13 RRSL_00677 o c Hypothetical Protein638722572 14.01235487 14.63682245 1.397 down 0.158 RRSL_00678 o c Transcriptional regulatory protein638722639 8.776079869 8.990597449 1.051 down 0.871 RRSL_00842 o c Potassium-transporting ATPase C chain( EC:3.6.3.12 )638722640 8.497029869 8.302297449 1.262 up 0.502 RRSL_00843 o c Potassium-transporting ATPase B chain( EC:3.6.3.12 )638722641 10.16317987 8.949222449 2.559 up 0.178 RRSL_00844 o c Potassium-transporting ATPase A chain( EC:3.6.3.12 )638722643 10.68352987 9.212847449 3.057 up 0.0919 RRSL_00847 o c Hypothetical Protein638722644 8.686504869 9.410947449 1.497 down 0.35 RRSL_00848 o c Hypothetical Protein638722645 10.42892987 10.70467245 1.097 down 0.79 RRSL_00850 o c ABC transporter permease protein638722646 10.00330487 10.25397245 1.078 down 0.4 RRSL_00851 o c Hypothetical Protein638722647 10.95920487 10.63949745 1.376 up 0.0488 RRSL_00852 o c Hypothetical Protein638722648 10.32920487 11.22404745 1.685 down 0.0249 RRSL_00853 o c Hypothetical Protein638722649 8.583354869 9.112522449 1.308 down 0.258 RRSL_00854 o c probable COG1804, CaiB, predicted acyl-CoA transferases/carnitine dehydratase638722650 12.61560487 12.83762245 1.057 down 0.796 RRSL_00855 o c Cell division inhibitor MinE638722651 12.16182987 12.82304745 1.433 down 0.113 RRSL_00856 o c Cell division inhibitor MinD638722652 11.76325487 12.62599745 1.648 down 0.0147 RRSL_00857 o c Cell division inhibitor MinC638722655 8.400254869 8.011522449 1.444 up 0.0408 RRSL_00860 o c 2-dehydropantoate 2-reductase( EC:1.1.1.169 )638722656 9.416779869 9.665497449 1.077 down 0.71 RRSL_00861 o c Hypothetical Protein638722660 11.81320487 11.65929745 1.227 up 0.204 RRSL_00529 o c Transcriptional regulator, AraC family638722664 7.846054869 7.890897449 1.069 up 0.696 RRSL_00533 o c Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex( EC:2.3.1.12 )638722669 8.728154869 8.323822449 1.46 up 0.246 RRSL_00539 o c 3',5'-cyclic-nucleotide phosphodiesterase( EC:3.1.4.17 )638722677 10.47387987 10.50977245 1.076 up 0.724 RRSL_00547 o c Ankyrin homolog precursor638722678 11.26455487 12.32087245 1.885 down 0.0179 RRSL_00548 o c Hypothetical Protein638722684 9.956579869 11.09939745 2.001 down 0.0881 RRSL_00746 o c Hypothetical membrane spanning protein638722691 8.384829869 8.055722449 1.385 up 0.103 RRSL_00753 o c Probable chemotaxis phosphataze (cheZ2)638722715 13.15915487 13.63979745 1.264 down 0.00266 RRSL_00789 o c Zinc finger protein638722718 11.02420487 11.62267245 1.372 down 0.054 RRSL_00792 o c Pterin-4-alpha-carbinolamine dehydratase( EC:4.2.1.96 )638722719 10.74950487 11.06777245 1.13 down 0.231 RRSL_00794 o c Phenylalanine-4-hydroxylase( EC:1.14.16.1 )638722721 8.863254869 9.167672449 1.119 down 0.519 RRSL_00795 o c Ornithine cyclodeaminase( EC:4.3.1.12 )638722723 11.03295487 12.09502245 1.892 down 0.000594 RRSL_00797 o c Heavy Metal Binding Protein638722724 7.993354869 8.402672449 1.203 down 0.277 RRSL_00798 o c Copper-exporting ATPase( EC:3.6.3.4 )638722725 11.24542987 11.33179745 1.039 up 0.788 RRSL_00799 o c Lysophospholipase L2( EC:3.1.1.5 )638722726 8.844229869 9.485897449 1.414 down 0.113 RRSL_00800 o c Oxidoreductase, GMC family( EC:1.1.99.1 )638722732 8.416379869 8.933272449 1.297 down 0.244 RRSL_00807 o c Hypothetical Protein638722739 9.959204869 8.924622449 2.259 up 0.144 RRSL_00599 o c Outer membrane protein638722742 14.93057987 15.00037245 1.051 up 0.695 RRSL_00601 o c Signal peptide protein638722745 10.38040487 10.23787245 1.217 up 0.0495 RRSL_00604 o c transmembrane protein638722746 10.44297987 10.09729745 1.401 up 0.193 RRSL_00605 o c hypothetical protein638722747 9.137629869 9.533822449 1.192 down 0.12 RRSL_00606 o c hypothetical protein638722749 9.413104869 10.01392245 1.374 down 0.013 RRSL_00608 o c hypothetical protein638722750 8.583829869 8.546797449 1.131 up 0.367 RRSL_00609 o c hypothetical protein638722762 10.59750487 11.40222245 1.583 down 0.0581 RRSL_00428 o c Hypothetical Protein

638722764 9.607804869 9.304547449 1.361 up 0.0986 RRSL_00430 o c Hypothetical Protein638722765 9.050954869 9.451922449 1.196 down 0.0717 RRSL_00431 o c Hypothetical Protein638722766 8.547479869 9.286972449 1.513 down 0.0346 RRSL_00432 o c Dethiobiotin synthetase( EC:6.3.3.3 )638722767 9.047654869 9.994072449 1.746 down 0.00663 RRSL_00433 o c 8-amino-7-oxononanoate synthase( EC:2.3.1.47 )638722768 8.969529869 10.01227245 1.867 down 0.00084 RRSL_00434 o c Adenosylmethionine-8-amino-7-oxononanoate aminotransferase( EC:2.6.1.62 )638722789 7.760379869 8.192697449 1.223 down 0.413 RRSL_00381 o c Hypothetical Protein638722794 8.027004869 7.793372449 1.297 up 0.022 RRSL_00387 o c FMN-dependent NADH-azoreductase( EC:1.6.99.2,EC:3.1.4.14 )638722804 8.385704869 8.646497449 1.086 down 0.649 RRSL_00399 o c Transmembrane Protein; tadG1638722805 8.041754869 7.837197449 1.271 up 0.408 RRSL_00400 o c TRANSMEMBRANE TIGHT ADHERENCE TADC-RELATED PROTEIN; tadC1638722806 9.024429869 7.836747449 2.512 up 0.124 RRSL_00401 o c TRANSMEMBRANE TIGHT ADHERENCE TADB-RELATED PROTEIN; tadB1638722807 7.633629869 7.294747449 1.395 up 0.337 RRSL_00402 o c SECRETION ATPASE; cpaF1638722808 8.017804869 7.648422449 1.425 up 0.198 RRSL_00403 o c PILUS ASSEMBLY PROTEIN; cpaE1638722809 8.187029869 8.325397449 1.002 up 0.996 RRSL_00404 o c lipoprotein638722810 9.080979869 7.465172449 3.381 up 0.0995 RRSL_00406 o c GspD-related protein; cpaC1638722811 8.478579869 7.944847449 1.597 up 0.057 RRSL_00407 o c TRANSMEMBRANE PILUS ASSEMBLY PROTEIN; cpaB1638722812 9.992754869 8.857197449 2.423 up 0.167 RRSL_00409 o c Prepilin Peptidase; cpaA1638722813 9.752629869 8.159247449 3.328 up 0.157 RRSL_00410 o c Putative Pilin Protein638722825 10.80727987 11.61434745 1.585 down 0.00572 RRSL_00342 o c Replicative DNA helicase( EC:3.6.1.- )638722826 13.52462987 14.52639745 1.815 down 0.0265 RRSL_00343 o c LSU ribosomal protein L9P638722827 14.62810487 15.65217245 1.843 down 0.00135 RRSL_00344 o c SSU ribosomal protein S18P638722828 16.50145487 16.93307245 1.222 down 0.0416 RRSL_00345 o c Primosomal replication protein N638722829 14.36892987 15.22424745 1.639 down 0.0209 RRSL_00346 o c SSU ribosomal protein S6P638722831 11.20152987 11.30879745 1.024 up 0.825 RRSL_00349 o c LexA repressor( EC:3.4.21.88 )638722834 9.344504869 9.636422449 1.109 down 0.382 RRSL_00352 o c Xaa-His dipeptidase( EC:3.4.13.3 )638722835 9.845954869 9.545272449 1.358 up 0.0993 RRSL_00353 o c Hypothetical Protein638722837 10.54765487 10.72564745 1.025 down 0.756 RRSL_00354 o c NIFR3-like protein638722840 11.96480487 12.88484745 1.715 down 0.0333 RRSL_00357 o c GTP-binding protein TypA/BipA638722841 11.73980487 10.05969745 3.535 up 0.0945 RRSL_00358 o c Transcriptional regulator, MarR family638722865 13.77907987 14.15797245 1.178 down 0.268 RRSL_00613 o c parA ParA638722866 10.91772987 11.71817245 1.578 down 0.101 RRSL_00614 o c parB ParB638722870 9.216829869 8.601672449 1.689 up 0.109 RRSL_00618 o c Transporter638722871 10.71977987 10.17139745 1.613 up 0.0847 RRSL_00619 o c dctD DctD638722900 11.66927987 11.93117245 1.086 down 0.66 RRSL_00307 o c dnaA DnaA638722901 13.45917987 13.87612245 1.21 down 0.111 RRSL_00308 o c DNA polymerase III, beta chain638722903 13.27915487 13.19264745 1.171 up 0.0832 RRSL_00310 o c DNA gyrase subunit B( EC:5.99.1.3 )638722921 10.76645487 10.08237245 1.772 up 0.0648 RRSL_00292 o c Na+ driven multidrug efflux pump (MATE family)638722922 10.08007987 10.40889745 1.138 down 0.287 RRSL_00293 o c Hypothetical Protein638722923 14.57527987 15.56907245 1.805 down 0.0104 RRSL_00294 o c LSU ribosomal protein L31P638722924 9.820204869 10.23487245 1.208 down 0.116 RRSL_00295 o c Hypothetical Protein638722926 7.775929869 7.234772449 1.605 up 0.00509 RRSL_00298 o c Transcriptional regulatory protein638722927 13.72142987 14.02582245 1.119 down 0.443 RRSL_00299 o c rho Rho638722928 13.22137987 13.83549745 1.387 down 0.109 RRSL_00300 o c Thioredoxin638722929 9.079679869 8.885872449 1.261 up 0.0336 RRSL_00301 o c Hypothetical cytosolic protein638722930 8.832279869 9.059197449 1.06 down 0.501 RRSL_00302 o c ATP-dependent nuclease subunit A638722932 12.28365487 13.29634745 1.828 down 0.038 RRSL_00304 o c Hypothetical transcriptional regulatory protein638722934 10.28425487 11.20397245 1.714 down 0.111 RRSL_00306 o c recR RecR638722952 8.502679869 8.974022449 1.256 down 0.188 RRSL_00223 o c 23S rRNA methyltransferase( EC:2.1.1.- )638722953 9.450254869 10.40407245 1.755 down 0.0419 RRSL_00224 o c Ribonuclease HII( EC:3.1.26.4 )638722954 10.00607987 11.00842245 1.815 down 0.0742 RRSL_00225 o c Lipid-A-disaccharide synthase( EC:2.4.1.182 )638722956 11.87400487 12.76419745 1.68 down 0.0387 RRSL_00227 o c (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase( EC:4.2.1.- )638722957 12.18160487 13.04974745 1.654 down 0.0128 RRSL_00228 o c UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase( EC:2.3.1.- )638722958 12.07605487 12.94607245 1.656 down 0.135 RRSL_00229 o c Hypothetical Protein638722959 11.70297987 12.29324745 1.364 down 0.308 RRSL_00230 o c Outer membrane protein638722960 13.39390487 13.26887245 1.203 up 0.0845 RRSL_00231 o c Membrane metalloprotease638722961 10.12687987 10.95562245 1.609 down 0.142 RRSL_00232 o c 1-deoxy-D-xylulose 5-phosphate reductoisomerase( EC:1.1.1.267 )638722962 12.64595487 12.92487245 1.099 down 0.657 RRSL_00233 o c Phosphatidate cytidylyltransferase( EC:2.7.7.41 )638722963 10.99240487 12.12542245 1.988 down 0.0535 RRSL_00234 o c Undecaprenyl pyrophosphate synthetase( EC:2.5.1.31 )

638722964 14.24355487 14.56029745 1.129 down 0.448 RRSL_00235 o c Ribosome Recycling Factor (RRF)638722965 11.79712987 12.87222245 1.909 down 0.0248 RRSL_00236 o c Uridylate kinase( EC:2.7.4.- )638722973 11.25825487 11.04632245 1.277 up 0.133 RRSL_00258 o c corB CorB638722974 11.15330487 11.76214745 1.382 down 0.236 RRSL_00259 o c PilB, Type IV pilus protein638722975 12.30902987 12.65029745 1.148 down 0.352 RRSL_00260 o c PilC638722976 10.38105487 10.70632245 1.135 down 0.383 RRSL_00261 o c PilD, Type 4 prepilin peptidase( EC:3.4.99.- )638722977 10.28292987 10.57852245 1.112 down 0.323 RRSL_00262 o c Dephospho-CoA kinase( EC:2.7.1.24 )638722978 11.36302987 12.30974745 1.747 down 0.0771 RRSL_00263 o c Hypothetical protein638722979 12.57605487 13.08529745 1.29 down 0.0577 RRSL_00264 o c Hypothetical Protein638722980 11.02567987 11.91297245 1.676 down 0.0219 RRSL_00265 o c MutT638722984 8.312054869 9.077522449 1.54 down 0.176 RRSL_00269 o c Cell wall endopeptidase, family M23/M37638722985 11.83077987 12.28394745 1.24 down 0.529 RRSL_00270 o c Hypothetical Protein638722986 11.93545487 12.68887245 1.528 down 0.00611 RRSL_00177 o c ABC transporter ATP-binding protein638722987 9.234604869 9.915047449 1.452 down 0.00887 RRSL_00178 o c Muramoyltetrapeptide carboxypeptidase( EC:3.4.17.13 )638722988 11.31507987 12.28492245 1.775 down 0.0117 RRSL_00179 o c queD QueD638722989 11.84242987 12.56124745 1.491 down 0.00471 RRSL_00181 o c Queuosine biosynthesis protein QueE638722992 8.841854869 9.152272449 1.124 down 0.559 RRSL_00183 o c HIPA protein638722993 8.814204869 8.024397449 1.907 up 0.0198 RRSL_00184 o c Arabinose efflux permease (AraJ)638722996 9.301404869 9.863597449 1.338 down 0.0861 RRSL_00187 o c Thioredoxin638722997 8.243954869 8.779172449 1.313 down 0.198 RRSL_00188 o c 2'-5' RNA ligase638722998 8.555004869 9.088422449 1.311 down 0.268 RRSL_00189 o c Protocatechuate 3,4-dioxygenase alpha chain( EC:1.13.11.3 )638723018 10.22672987 11.35604745 1.982 down 0.0143 RRSL_00205 o c Hypothetical Protein( EC:2.5.1.19 )638723019 10.16937987 11.18404745 1.831 down 0.0356 RRSL_00206 o c Cytidylate kinase( EC:2.7.4.14 )638723020 15.85422987 16.23142245 1.177 down 0.0118 RRSL_00207 o c SSU ribosomal protein S1P638723022 13.62345487 13.89219745 1.092 down 0.449 RRSL_00209 o c Hypothetical Protein638723023 10.95247987 11.62587245 1.445 down 0.136 RRSL_00210 o c Tetratricopeptide repeat family protein638723024 9.460804869 10.74922245 2.214 down 0.0592 RRSL_00211 o c UDP-glucose 6-dehydrogenase( EC:1.1.1.22 )638723025 12.56522987 13.53322245 1.773 down 0.102 RRSL_00212 o c D-glycero-D-manno-heptose-7-phosphate 1-kinase( EC:2.7.1.- )638723026 12.25162987 13.14349745 1.681 down 0.05 RRSL_00213 o c ADP-L-glycero-D-manno-heptose-6-epimerase( EC:5.1.3.20 )638723028 11.57247987 12.07517245 1.284 down 0.0527 RRSL_00215 o c Cysteine synthase( EC:2.5.1.47,EC:4.2.99.8 )638723029 10.22872987 11.13812245 1.702 down 0.0589 RRSL_00217 o c Membrane-bound lytic murein transglycosylase B( EC:3.2.1.- )638723054 11.81335487 11.92052245 1.024 up 0.849 RRSL_00142 o c oppB OppB638723055 11.55290487 11.45182245 1.183 up 0.254 RRSL_00143 o c oppC OppC638723056 9.582129869 10.47934745 1.688 down 0.0611 RRSL_00144 o c oppF OppF638723057 14.06630487 14.46789745 1.197 down 0.113 RRSL_00145 o c Hypothetical Protein638723058 9.770104869 10.62497245 1.639 down 0.0288 RRSL_00146 o c Serine protease( EC:3.4.21.- )638723060 14.74710487 15.25747245 1.291 down 0.00708 RRSL_00133 o c UDP-glucuronate 4-dehydrogenase (decarboxylating)( EC:1.1.1.- )638723061 11.35875487 12.45344745 1.935 down 0.0212 RRSL_00134 o c Chitooligosaccharide deacetylase( EC:3.5.1.- )638723062 11.42662987 12.10394745 1.449 down 0.0814 RRSL_00135 o c oxidoreductase, bacterioferritin co-migratory protein638723063 12.77072987 12.02542245 1.849 up 0.0387 RRSL_00136 o c probable conserved hypothetical protein638723064 8.335104869 8.634922449 1.115 down 0.749 RRSL_00137 o c Hypothetical Protein638723065 9.284229869 10.15907245 1.662 down 0.0555 RRSL_00138 o c invasion-associated protein, p60638723083 9.416854869 9.360997449 1.146 up 0.33 RRSL_00127 o c ATP synthase epsilon chain( EC:3.6.3.14 )638723091 7.495329869 7.583622449 1.037 up 0.705 RRSL_00109 o c phnT PhnT( EC:3.6.3.25 )638723093 11.20682987 11.60942245 1.198 down 0.257 RRSL_00071 o c Hypothetical Protein638723094 10.22010487 10.30297245 1.041 up 0.743 RRSL_00072 o c Hypothetical membrane spanning protein638723095 8.832679869 8.705747449 1.204 up 0.232 RRSL_00073 o c Undecaprenyl-phosphate-4-amino-L-arabinose-- lipid A 4-amino-L-arabinosyltransferase( EC:2.4.2.- )638723096 13.41450487 13.81872245 1.199 down 0.469 RRSL_00074 o c transmembrane small multi-drug resistance protein638723097 11.04110487 12.03382245 1.803 down 0.00155 RRSL_00075 o c UDP-4-amino-L-arabinose synthase( EC:2.6.1.- )638723104 11.37642987 11.98847245 1.385 down 0.263 RRSL_00097 o c Phosphoenolpyruvate synthase( EC:2.7.9.2 )638723105 10.14845487 10.81714745 1.44 down 0.0157 RRSL_00098 o c Hypothetical Protein638723106 12.48545487 12.57762245 1.034 up 0.555 RRSL_00099 o c stomatin like protein638723107 11.51617987 11.99714745 1.265 down 0.0824 RRSL_00100 o c SsrA-binding protein638723108 11.33172987 11.56174745 1.063 down 0.702 RRSL_00101 o c Hypothetical cytosolic protein638723109 8.955129869 9.437497449 1.266 down 0.196 RRSL_00102 o c Hypothetical Protein638723113 10.02395487 10.77097245 1.521 down 0.0742 RRSL_00085 o c lpxK LpxK( EC:2.7.1.130 )638723114 13.58760487 13.77854745 1.034 down 0.677 RRSL_00086 o c conserved cytosolic protein

638723115 9.362004869 10.14739745 1.562 down 0.0526 RRSL_00087 o c 3-deoxy-manno-octulosonate cytidylyltransferase( EC:2.7.7.38 )638723116 11.85842987 12.28324745 1.216 down 0.183 RRSL_00088 o c Adenylate kinase / Nucleoside-diphosphate kinase( EC:2.7.4.3,EC:2.7.4.6 )638723120 9.902854869 9.495997449 1.462 up 0.129 RRSL_00062 o c Gamma-glutamyltranspeptidase( EC:2.3.2.2 )638723133 12.62942987 13.47852245 1.632 down 0.0399 RRSL_00048 o c GMP synthase (glutamine-hydrolyzing)( EC:6.3.5.2 )638723134 13.39465487 14.05934745 1.436 down 0.0694 RRSL_00050 o c Inosine-5'-monophosphate dehydrogenase( EC:1.1.1.205 )638723139 9.249254869 9.364872449 1.018 up 0.922 RRSL_00035 o c Malate:quinone oxidoreductase( EC:1.1.99.16 )638723145 8.905929869 8.653372449 1.314 up 0.177 RRSL_00037 o c Hypothetical membrane spanning protein638723146 7.649579869 8.084472449 1.225 down 0.275 RRSL_00038 o c Transcriptional regulators, LysR family638723150 10.38687987 10.54412245 1.01 down 0.929 RRSL_00045 o c Glutamate/aspartate-binding protein638718744 12.13757987 11.43432245 1.796 up 0.0157 RRSL_04595 o 1-acyl-sn-glycerol-3-phosphate acyltransferase( EC:2.3.1.51 )638718764 7.860504869 8.449947449 1.363 down 0.157 RRSL_04615 o Hypothetical Protein638718765 8.979229869 8.922572449 1.147 up 0.435 RRSL_04616 o ABC transporter ATP-binding protein638718766 11.10890487 10.29592245 1.938 up 0.219 RRSL_04617 o ABC transporter permease protein638718767 9.334329869 8.996297449 1.394 up 0.0858 RRSL_04618 o ABC transporter substrate-binding protein638718771 8.460404869 7.989572449 1.528 up 0.236 RRSL_04622 o Hypothetical Protein638718772 8.994554869 7.288022449 3.6 up 0.105 RRSL_04624 o Hypothetical Protein638718773 8.814554869 8.707172449 1.188 up 0.586 RRSL_04623 o Hypothetical Protein638718774 9.614529869 9.612947449 1.104 up 0.523 RRSL_04625 o Translation initiation inhibitor638718776 10.31552987 11.52244745 2.092 down 0.109 RRSL_04626 o Hypothetical Protein638718777 9.540354869 10.07717245 1.315 down 0.0949 RRSL_04628 o Sulfate transporter638718778 9.475829869 9.414822449 1.15 up 0.445 RRSL_04629 o Hypothetical Protein638718779 9.025279869 8.606672449 1.474 up 0.0131 RRSL_04630 o Virulence protein638718780 8.226654869 8.327622449 1.028 up 0.843 RRSL_04631 o oxacillin resistance-associated protein FmtC638718782 7.453879869 7.684472449 1.063 down 0.721 RRSL_04633 o Hypothetical Protein638718783 8.151754869 7.527422449 1.7 up 0.0232 RRSL_04634 o transmembrane hypothetical638718784 13.23877987 12.88664745 1.408 up 0.019 RRSL_04635 o Hypothetical Protein638718785 9.296179869 9.744472449 1.236 down 0.279 RRSL_04636 o Hypothetical Protein638718787 12.36275487 11.75514745 1.68 up 0.00994 RRSL_04638 o 1-aminocyclopropane-1-carboxylate oxidase( EC:1.- )638718788 12.68590487 13.19727245 1.292 down 0.148 RRSL_04639 o probable oxidoreductase L-ascorbate oxidase (ascorbase)638718789 8.935729869 9.063447449 1.009 up 0.956 RRSL_04640 o Protein U precursor638718790 8.109254869 8.550647449 1.23 down 0.446 RRSL_04641 o sefC SefC638718791 8.886454869 9.877447449 1.801 down 0.143 RRSL_04642 o ecpD EcpD638718792 13.10360487 13.27119745 1.018 down 0.913 RRSL_04643 o Protein U precursor638718799 8.471129869 8.886222449 1.208 down 0.192 RRSL_04651 o Hypothetical Protein638718805 8.694904869 8.359522449 1.391 up 0.0915 RRSL_04657 o Hypothetical Protein638718806 9.116304869 8.958897449 1.23 up 0.167 RRSL_04658 o Na+ driven multidrug efflux pump638718811 11.66285487 12.80459745 2 down 0.00634 RRSL_04663 o Hypothetical Protein638718812 7.614779869 7.181422449 1.489 up 0.105 RRSL_04664 o Probable transmembrane methyl-accepting chemotaxis protein638718813 8.532404869 8.616647449 1.04 up 0.848 RRSL_04665 o Sensor protein FixL( EC:2.7.3.- )638718816 9.493804869 9.191297449 1.36 up 0.0756 RRSL_04668 o Hypothetical Protein638718819 13.32672987 12.99712245 1.386 up 0.127 RRSL_04671 o Hypothetical Protein638718820 11.82477987 11.81594745 1.109 up 0.573 RRSL_04672 o Hypothetical Protein638718821 13.42110487 14.50619745 1.923 down 0.000769 RRSL_04673 o Hypothetical Protein638718822 8.289529869 9.285547449 1.807 down 0.00896 RRSL_04675 o Type I secretion outer membrane protein638718823 9.503454869 10.19937245 1.468 down 0.0404 RRSL_04676 o Transmembrane drug efflux pump638718824 8.196129869 9.092097449 1.686 down 0.04 RRSL_04677 o Transmembrane drug efflux pump638718826 10.23132987 10.55729745 1.136 down 0.214 RRSL_04679 o ompR OmpR638718827 9.152554869 9.374297449 1.057 down 0.602 RRSL_04680 o Osmolarity sensor protein envZ( EC:2.7.3.- )638718828 13.14960487 13.09242245 1.147 up 0.118 RRSL_04681 o Hypothetical Protein638718829 9.563529869 10.26972245 1.478 down 0.00271 RRSL_04682 o Undecaprenyl-phosphate-4-amino-L-arabinose-- lipid A 4-amino-L-arabinosyltransferase( EC:2.4.2.- )638718830 10.09837987 8.864072449 2.595 up 0.144 RRSL_04683 o Hypothetical Protein638718833 10.29062987 10.03259745 1.319 up 0.113 RRSL_04687 o DfrA protein638718835 8.363279869 9.002847449 1.412 down 0.0591 RRSL_04689 o Transcriptional regulator, RpiR family638718837 8.681579869 9.215497449 1.312 down 0.0863 RRSL_04691 o 2-dehydro-3-deoxygluconokinase( EC:2.7.1.45 )638718838 10.88910487 11.75164745 1.648 down 0.00241 RRSL_04692 o Type I secretion adaptor protein (HlyD family)638718840 11.47097987 11.94404745 1.258 down 0.32 RRSL_04694 o Transmembrane type 1 secretion system outer membrane efflux protein638718850 8.235254869 8.417547449 1.028 down 0.795 RRSL_04705 o Two component system histidine kinase / Two component response regulator( EC:2.7.3.- )

638718851 9.049104869 8.818822449 1.294 up 0.219 RRSL_04706 o Macrolide-efflux protein638718852 10.86717987 10.67192245 1.263 up 0.197 RRSL_04708 o Hypothetical Protein638718856 10.27765487 10.51259745 1.066 down 0.79 RRSL_04712 o integral membrane protein / hemolysin638718857 9.202929869 9.444022449 1.071 down 0.832 RRSL_04713 o Hypothetical Protein638718858 7.802504869 8.611722449 1.588 down 0.218 RRSL_04714 o Hypothetical Protein638718859 9.440454869 9.342947449 1.18 up 0.599 RRSL_04715 o Transcriptional regulator, TetR family638718860 9.020279869 8.607397449 1.468 up 0.144 RRSL_04716 o Hypothetical Protein638718861 8.899404869 9.347397449 1.236 down 0.135 RRSL_04717 o Sensor protein baeS( EC:2.7.3.- )638718862 11.74790487 11.23127245 1.578 up 0.0633 RRSL_04718 o Hypothetical Protein638718863 11.02122987 10.72859745 1.351 up 0.0133 RRSL_04719 o Hypothetical Protein638718864 10.88237987 10.25342245 1.706 up 0.00313 RRSL_04720 o Universal stress protein family638718865 12.55877987 12.09564745 1.52 up 0.0237 RRSL_04721 o Hypothetical Protein638718866 10.06750487 10.23462245 1.017 down 0.878 RRSL_04722 o Transcriptional regulator, AraC family638718867 7.744004869 7.602547449 1.216 up 0.0955 RRSL_04723 o Hypothetical Protein638718870 8.324379869 7.508322449 1.942 up 0.169 RRSL_04727 o Sensory box/GGDEF family protein638718872 9.487754869 9.825622449 1.145 down 0.286 RRSL_04729 o Transporter638718873 7.673179869 7.815647449 1 down 0.996 RRSL_04730 o modC ModC638718874 12.31062987 11.02474745 2.689 up 0.196 RRSL_04731 o modB ModB638718876 9.310704869 9.116097449 1.262 up 0.394 RRSL_04733 o Hypothetical Protein638718878 12.17842987 12.86139745 1.455 down 0.0327 RRSL_04735 o Glutamate/aspartate-binding protein638718879 11.15025487 10.36627245 1.899 up 0.0029 RRSL_04736 o Hypothetical Protein638718882 7.416454869 7.911272449 1.277 down 0.252 RRSL_04739 o Probable outer membrane drug efflux protein638718885 7.329579869 8.363297449 1.855 down 0.0286 RRSL_04742 o Hypothetical Protein638718886 11.04810487 11.83637245 1.565 down 0.0906 RRSL_04743 o Transcriptional regulators, LysR family638718887 15.35235487 15.27342245 1.165 up 0.0834 RRSL_04744 o Membrane-bound lytic murein transglycosylase B( EC:3.2.1.- )638718888 7.322354869 7.503247449 1.027 down 0.877 RRSL_04745 o Zinc finger protein638718895 11.05650487 11.18692245 1.007 up 0.941 RRSL_04753 o Hypothetical Protein638718896 8.655254869 9.301972449 1.419 down 0.0322 RRSL_04754 o Hypothetical Protein638718899 8.891629869 7.643772449 2.619 up 0.0928 RRSL_04757 o Probable transmembrane methyl-accepting chemotaxis protein638718900 11.93580487 12.14224745 1.045 down 0.901 RRSL_04758 o H-NS-like proteins638718901 10.75862987 10.31487245 1.5 up 0.00765 RRSL_04759 o Hypothetical Protein638718903 9.595304869 9.287572449 1.365 up 0.0672 RRSL_04761 o Transcriptional regulators, LysR family638718904 10.10790487 9.945197449 1.234 up 0.182 RRSL_04762 o Hypothetical Protein638718905 10.47110487 10.70837245 1.068 down 0.6 RRSL_04763 o Hypothetical Protein638718911 9.299704869 8.488997449 1.935 up 0.0159 RRSL_04770 o Hypothetical Protein638718912 8.973929869 9.585322449 1.384 down 0.0356 RRSL_04771 o Hypothetical Protein638718913 14.22712987 14.68199745 1.242 down 0.165 RRSL_04772 o Universal stress protein family638718919 6.813179869 6.786047449 1.124 up 0.575 RRSL_04779 o Hypothetical Protein638718920 8.453279869 8.929547449 1.261 down 0.0975 RRSL_04780 o Sensor protein qseC( EC:2.7.3.- )638718921 8.901779869 8.537597449 1.419 up 0.0651 RRSL_04782 o Protease Do( EC:3.4.21.- )638718922 8.993154869 9.780897449 1.564 down 0.0147 RRSL_04783 o 1,3-propanediol dehydrogenase( EC:1.1.1.202 )638718923 11.02177987 11.88362245 1.647 down 0.0119 RRSL_04784 o Transporter638718925 14.49007987 14.84017245 1.155 down 0.0881 RRSL_04786 o Hypothetical Protein638718927 11.48835487 11.90714745 1.211 down 0.567 RRSL_04788 o Hypothetical Protein638718932 7.676029869 7.562822449 1.193 up 0.53 RRSL_04793 o Hemolysin638718937 8.436804869 8.381272449 1.146 up 0.433 RRSL_04392 o Ribokinase( EC:2.7.1.15 )638718954 9.033779869 7.805697449 2.584 up 0.26 RRSL_04410 o Transcriptional regulator, ArsR family638718955 9.749529869 9.840322449 1.035 up 0.815 RRSL_04411 o Glutathione S-transferase( EC:2.5.1.18 )638718959 8.801254869 8.835222449 1.077 up 0.505 RRSL_04415 o Metal-dependent hydrolase related to alanyl-tRNA synthetase638718971 9.978454869 10.01032245 1.079 up 0.185 RRSL_04427 o hypothetical protein638718979 10.14530487 10.33699745 1.035 down 0.773 RRSL_04434 o DNA integration/recombination/invertion protein638718980 9.321529869 9.618347449 1.113 down 0.48 RRSL_04435 o hypothetical protein638718981 7.068454869 7.806122449 1.511 down 0.0125 RRSL_04436 o hypothetical protein638718984 6.977954869 7.934647449 1.759 down 0.0546 RRSL_04441 o hypothetical protein638718985 12.97057987 12.76102245 1.275 up 0.259 RRSL_04443 o hypothetical protein638718986 12.51150487 12.58639745 1.047 up 0.833 RRSL_04444 o hypothetical protein638718987 12.23097987 12.36759745 1.003 up 0.992 RRSL_04445 o VgrG protein

638719024 11.57960487 13.18974745 2.767 down 0.0591 RRSL_04484 o Lysine-specific permease638719025 8.332529869 7.594322449 1.84 up 0.0356 RRSL_04485 o probable DNA damage inducible protein F638719027 9.563804869 9.593647449 1.08 up 0.789 RRSL_04487 o hypothetical protein638719028 8.090279869 8.423697449 1.142 down 0.553 RRSL_04489 o HmsH638719029 8.594154869 8.301172449 1.351 up 0.261 RRSL_04490 o HmsF protein638719030 8.642554869 8.030247449 1.686 up 0.178 RRSL_04491 o HmsR638719031 8.037154869 8.296397449 1.084 down 0.587 RRSL_04492 o hypothetical protein638719032 9.312254869 9.821922449 1.29 down 0.262 RRSL_04493 o Type I secretion outer membrane protein638719033 9.776529869 10.46544745 1.461 down 0.109 RRSL_04494 o Type I secretion adaptor protein (HlyD family)

638719034 8.678679869 9.621322449 1.742 down 0.178 RRSL_04495 oType I protein secretion ATP-binding protein / Type I protein secretion transmembrane protein subunit / Type I secretion processing peptidase

638719035 11.60655487 11.28079745 1.382 up 0.00749 RRSL_04496 o Hemolysin-type Calcium-binding protein - RTX toxin638719037 12.94272987 12.90377245 1.133 up 0.032 RRSL_04497 o GspF-related protein638719038 7.066254869 7.151047449 1.04 up 0.721 RRSL_04499 o GspE-related protein638719039 8.033704869 7.970972449 1.152 up 0.303 RRSL_04500 o hypothetical protein638719040 8.442604869 8.631722449 1.033 down 0.909 RRSL_04501 o hypothetical protein638719112 13.33575487 12.73459745 1.673 up 0.0375 RRSL_04575 o hypothetical protein638719131 8.354329869 9.155172449 1.579 down 0.053 RRSL_04278 o Hypothetical Protein638719134 13.12810487 13.25072245 1.013 up 0.973 RRSL_04281 o Hypothetical Protein638719135 9.946554869 9.741847449 1.271 up 0.192 RRSL_04282 o Hypothetical Protein638719137 10.52885487 9.774047449 1.861 up 0.0266 RRSL_04285 o Antibiotic/siderophore biosynthesis protein638719138 8.861704869 9.333422449 1.257 down 0.153 RRSL_04286 o Probable Na+ driven multidrug efflux pump638719139 11.00597987 11.59839745 1.366 down 0.427 RRSL_04287 o 4'-phosphopantetheinyl transferase( EC:2.7.8.- )638719148 7.896604869 7.941597449 1.069 up 0.667 RRSL_04298 o 2-dehydropantoate 2-reductase( EC:1.1.1.169 )638719149 9.168504869 9.446397449 1.099 down 0.611 RRSL_04299 o UbiA prenyltransferase family protein638719150 8.779929869 9.771072449 1.801 down 0.00435 RRSL_04300 o L-gulonolactone oxidase( EC:1.1.3.8 )638719151 10.30102987 10.90829745 1.38 down 0.223 RRSL_04301 o NADH-ubiquinone oxidoreductase 39-40 kDa subunit homolog638719152 9.743404869 10.56014745 1.596 down 0.0398 RRSL_04302 o NADPH-dependent glutamate synthase beta chain and related oxidoreductases638719153 10.04862987 10.19539745 1.003 down 0.978 RRSL_04303 o Hypothetical Protein638719170 9.936929869 9.821197449 1.195 up 0.659 RRSL_04321 o Hypothetical Protein638719174 9.855329869 9.363172449 1.551 up 0.134 RRSL_04325 o Transcriptional regulators, LysR family638719175 9.228654869 7.863622449 2.841 up 0.192 RRSL_04326 o Hypothetical Protein638719182 11.99647987 11.89589745 1.182 up 0.323 RRSL_04334 o Lipid A biosynthesis (KDO) 2-(lauroyl)-lipid IVA acyltransferase( EC:2.3.1.- )638719184 10.37200487 9.831422449 1.604 up 0.0803 RRSL_04336 o Hypothetical Protein638719189 9.585454869 9.224722449 1.416 up 0.125 RRSL_04342 o Leucine-responsive regulatory protein638719191 8.638654869 7.818347449 1.948 up 0.106 RRSL_04344 o probable haemagglutinin-related protein638719192 13.68345487 12.88389745 1.92 up 0.0125 RRSL_04345 o Hypothetical Protein638719193 10.88967987 10.57499745 1.372 up 0.299 RRSL_04346 o putative DNA-binding protein638719194 12.73420487 11.86717245 2.012 up 0.101 RRSL_04347 o Hypothetical protein638719200 12.31335487 13.17794745 1.65 down 0.00316 RRSL_04353 o Hypothetical Protein638719201 10.91897987 11.78132245 1.647 down 0.0656 RRSL_04354 o probable conserved hypothetical protein638719202 13.04952987 13.25797245 1.047 down 0.663 RRSL_04355 o Hypothetical Protein638719203 13.56460487 13.70422245 1.001 up 0.988 RRSL_04356 o Hypothetical Protein638719210 9.385404869 9.441122449 1.061 up 0.567 RRSL_04366 o Hypothetical Protein638719211 9.731079869 10.82432245 1.933 down 0.0127 RRSL_04367 o phosphomethylpyrimidine kinase / hydroxymethylpyrimidine kinase( EC:2.7.1.49,EC:2.7.4.7 )638719231 11.56380487 11.24019745 1.38 up 0.0629 RRSL_04387 o Hypothetical Protein638719248 8.995929869 9.707422449 1.484 down 0.243 RRSL_04066 o Glutathione S-transferase( EC:2.5.1.18 )638719253 8.376279869 8.981197449 1.378 down 0.0149 RRSL_04071 o Paraquat-inducible protein A638719275 10.91035487 10.15274745 1.865 up 0.275 RRSL_04094 o mosC MosC638719334 8.068479869 9.151022449 1.919 down 0.0234 RRSL_04158 o signal peptide638719338 7.953529869 8.331972449 1.178 down 0.344 RRSL_04162 o hypothetical protein638719343 9.426229869 9.421197449 1.107 up 0.764 RRSL_04168 o probable hypothetical protein638719405 10.37382987 11.29119745 1.711 down 0.00718 RRSL_04232 o Aspartate aminotransferase( EC:2.6.1.1 )638719412 9.398479869 9.462522449 1.055 up 0.736 RRSL_04239 o probable conserved hypothetical protein638719476 10.45397987 11.12619745 1.444 down 0.0474 RRSL_03854 o rdgC RdgC638719486 10.59252987 9.989747449 1.675 up 0.0177 RRSL_03865 o Probable transmembrane theornine efflux protein.638719526 8.895279869 8.769197449 1.203 up 0.205 RRSL_03906 o Hypothetical Protein

638719529 8.211404869 7.780797449 1.486 up 0.0228 RRSL_03909 o (R)-specific enoyl-CoA hydratase( EC:4.2.1.- )638719531 11.30912987 10.98059745 1.385 up 0.0172 RRSL_03911 o amide-urea binding protein precursor638719533 10.00247987 8.987472449 2.229 up 0.136 RRSL_03913 o amide-urea transport system permease protein638719536 8.074279869 8.840872449 1.542 down 0.0448 RRSL_03916 o ureD UreD638719540 9.853829869 9.290647449 1.63 up 0.195 RRSL_03921 o Shikimate kinase( EC:2.7.1.71 )638719545 8.459204869 8.658747449 1.04 down 0.896 RRSL_03926 o CHRB protein638719546 9.394954869 9.235847449 1.231 up 0.144 RRSL_03927 o Chromate transport protein638719547 7.215004869 7.790647449 1.35 down 0.117 RRSL_03928 o CHRB protein638719548 9.126754869 9.159872449 1.078 up 0.729 RRSL_03929 o Histidine-rich glycoprotein precursor.638719549 9.985754869 10.88269745 1.687 down 0.0642 RRSL_03930 o Icc protein638719561 9.934879869 9.756047449 1.248 up 0.502 RRSL_03942 o Putative lactonase638719572 12.82302987 13.56404745 1.515 down 0.0535 RRSL_03953 o L-phenylalanine oxidase( EC:1.13.12.9 )638719583 9.893779869 10.66317245 1.545 down 0.0357 RRSL_03964 o hypothetical protein638719584 10.11975487 9.596947449 1.585 up 0.177 RRSL_03965 o Protease Do( EC:3.4.21.- )638719586 10.51875487 10.60077245 1.042 up 0.852 RRSL_03967 o Short chain dehydrogenase638719587 10.51445487 9.485122449 2.251 up 0.133 RRSL_03968 o hypothetical protein638719601 8.126204869 8.219347449 1.034 up 0.922 RRSL_03983 o 5-nitroimidazole antibiotic resistance protein638719604 12.71485487 11.88069745 1.966 up 0.0595 RRSL_03986 o putative transmembrane protein638719605 11.21907987 10.59814745 1.696 up 0.0625 RRSL_03987 o putative transmembrane protein638719617 13.19965487 13.73282245 1.311 down 0.086 RRSL_03999 o gspG GspG638719619 12.62982987 12.63424745 1.099 up 0.721 RRSL_04001 o putative calcium-binding protein638719632 8.801554869 9.296672449 1.277 down 0.16 RRSL_04015 o GspE-related protein638719633 11.04767987 11.23289745 1.03 down 0.893 RRSL_04016 o Transmembrane protein638719634 10.73640487 11.24482245 1.289 down 0.166 RRSL_04017 o proline-rich signal peptide638719635 8.008804869 8.539772449 1.309 down 0.272 RRSL_04018 o GspG-related protein638719636 8.338854869 8.594347449 1.082 down 0.775 RRSL_04019 o GspG-related protein638719637 9.921029869 10.28739745 1.168 down 0.575 RRSL_04020 o Transmembrane protein638719638 11.85017987 12.17024745 1.131 down 0.686 RRSL_04021 o GspG-related protein638719640 10.34752987 11.55464745 2.092 down 0.334 RRSL_04023 o hypothetical protein transmembrane protein638719641 8.787679869 8.713597449 1.161 up 0.239 RRSL_04024 o hypothetical protein638719643 15.05017987 14.22207245 1.958 up 0.00226 RRSL_04026 o hypothetical protein638719644 13.85177987 13.31854745 1.596 up 0.0319 RRSL_04027 o Cysteine desulfurase638719645 14.71910487 14.05529745 1.747 up 0.00879 RRSL_04028 o putative methyltransferase638719647 9.780479869 11.07869745 2.229 down 0.0525 RRSL_04030 o hypothetical protein638719648 10.64960487 11.15682245 1.288 down 0.459 RRSL_04031 o hypothetical protein638719658 13.16445487 13.12357245 1.134 up 0.35 RRSL_04044 o Biotin synthase( EC:2.8.1.6 )638719669 9.410279869 10.01749745 1.38 down 0.00581 RRSL_03450 o Hypothetical Protein638719682 11.78937987 12.49947245 1.482 down 0.00938 RRSL_03464 o hypothetical protein638719683 12.82135487 13.28084745 1.246 down 0.0023 RRSL_03465 o Hypothetical Protein638719684 12.01860487 12.67002245 1.423 down 0.0088 RRSL_03467 o Hypothetical Protein638719685 12.59317987 13.14732245 1.33 down 0.0115 RRSL_03468 o Hypothetical Protein638719748 9.108654869 9.511197449 1.198 down 0.534 RRSL_03533 o 4-hydroxybenzoate 3-monooxygenase( EC:1.14.13.2 )638719773 10.42342987 10.50862245 1.039 up 0.865 RRSL_03732 o hypothetical protein638719793 11.53442987 11.02809745 1.567 up 0.085 RRSL_03754 o Transcriptional regulator, AraC family638719794 10.17115487 9.960372449 1.276 up 0.148 RRSL_03755 o low-specificity threonine aldolase( EC:4.1.2.5 )638719799 9.442129869 9.384497449 1.148 up 0.368 RRSL_03761 o Transporter638719807 11.99732987 12.73387245 1.51 down 0.0223 RRSL_03770 o gene II and X proteins638719813 11.57515487 12.61959745 1.869 down 0.0327 RRSL_03776 o hypothetical protein638719820 7.859029869 8.113322449 1.081 down 0.58 RRSL_03783 o hypothetical protein638719857 10.78352987 10.94862245 1.016 down 0.933 RRSL_03555 o Potassium channel protein638719858 9.989554869 9.631597449 1.413 up 0.131 RRSL_03556 o Hypothetical Protein638719890 8.755379869 9.192072449 1.226 down 0.0552 RRSL_03588 o ABC transporter periplasmic protein.638719929 15.55710487 16.23467245 1.449 down 0.00414 RRSL_03628 o Hypothetical Protein638719985 9.915129869 10.83622245 1.716 down 0.0419 RRSL_02695 o PhnB protein638719993 10.54885487 11.10299745 1.33 down 0.00927 RRSL_02685 o czcD CzcD638720014 15.71082987 15.63149745 1.165 up 0.093 RRSL_02664 o Hypothetical Protein638720018 8.952154869 8.224472449 1.826 up 0.231 RRSL_02658 o Probable transmembrane methyl-accepting chemotaxis protein

638720056 12.72115487 12.01392245 1.801 up 0.125 RRSL_03286 o Hypothetical Protein638720068 14.29372987 14.65529745 1.164 down 0.268 RRSL_03297 o Hypothetical Protein638720076 14.83062987 15.45717245 1.399 down 0.00516 RRSL_03305 o Protein translocase subunit secB638720089 11.05247987 11.49664745 1.233 down 0.0495 RRSL_03319 o Ammonium transporter / Methylammonium transporter638720090 11.66357987 12.56039745 1.687 down 0.0451 RRSL_03320 o Nitrogen regulatory protein GlnK638720091 10.89780487 11.97314745 1.91 down 0.059 RRSL_03321 o Hypothetical Protein638720138 9.089779869 9.366397449 1.098 down 0.527 RRSL_03658 o oligopeptide transporter638720140 10.94325487 11.28657245 1.149 down 0.028 RRSL_03660 o Hypothetical Protein638720150 8.131029869 8.029722449 1.183 up 0.365 RRSL_03671 o Transcriptional regulators, LysR family638720151 11.15935487 10.40587245 1.859 up 0.0225 RRSL_03672 o Glutathione S-transferase( EC:2.5.1.18 )638720164 15.92155487 16.42212245 1.282 down 0.0278 RRSL_03685 o ATP synthase C chain( EC:3.6.3.14 )638720172 9.813629869 7.746222449 4.623 up 0.0937 RRSL_03693 o short chain dehydrogenase638720176 9.923304869 8.616322449 2.729 up 0.086 RRSL_03696 o NADPH-dependent glutamate synthase beta chain and related oxidoreductases638720182 8.808204869 8.029397449 1.892 up 0.0168 RRSL_03704 o Sensor protein luxN( EC:2.7.3.- )638720184 7.596904869 7.585622449 1.111 up 0.523 RRSL_03706 o Transcriptional regulators, LysR family638720187 9.952529869 9.310772449 1.721 up 0.0915 RRSL_03709 o Transcriptional regulator, MarR family638720193 8.262629869 8.143172449 1.198 up 0.337 RRSL_03715 o Benzaldehyde dehydrogenase (NAD+)( EC:1.2.1.28 )638720194 7.770804869 7.265022449 1.566 up 0.112 RRSL_03716 o Hypothetical Protein638720195 8.780554869 7.130272449 3.462 up 0.0601 RRSL_03718 o Hypothetical Protein638720196 9.490679869 8.543797449 2.126 up 0.105 RRSL_03719 o Lipase( EC:3.1.1.3 )638720198 9.167554869 9.247497449 1.043 up 0.493 RRSL_03721 o Putative lactonase638720199 9.906054869 8.878322449 2.249 up 0.119 RRSL_03722 o Transporter, MFS superfamily638720200 7.617754869 8.312172449 1.466 down 0.111 RRSL_03723 o maltooligosyltrehalose synthase( EC:5.4.99.16 )638720202 7.814979869 7.589072449 1.29 up 0.0386 RRSL_03725 o maltooligosyltrehalose trehalohydrolase( EC:3.2.1.141 )638720203 9.099004869 9.504322449 1.2 down 0.193 RRSL_03726 o glgX GlgX638720205 9.416579869 8.988772449 1.484 up 0.0966 RRSL_03365 o Transcriptional regulator, GntR family / TYROSINE AMINOTRANSFERASE( EC:2.6.1.5 )638720207 10.56100487 10.70307245 1 RRSL_03368 o D-beta-hydroxybutyrate dehydrogenase( EC:1.1.1.30 )638720208 11.50827987 11.42334745 1.17 up 0.363 RRSL_03369 o Serine protease( EC:3.4.21.- )638720218 8.097529869 8.187672449 1.036 up 0.877 RRSL_03381 o Hypothetical Protein638720219 12.66360487 12.32999745 1.39 up 0.00649 RRSL_03383 o Transcriptional regulator, MerR family638720220 10.81167987 10.59869745 1.278 up 0.223 RRSL_03384 o Hypothetical membrane associated protein638720232 11.20822987 11.74882245 1.318 down 0.0833 RRSL_03396 o Hypothetical Protein( EC:2.3.3.5 )638720234 8.692404869 9.689272449 1.808 down 0.0153 RRSL_03398 o FldA protein638720235 8.869729869 9.350097449 1.264 down 0.193 RRSL_03399 o Hypothetical Protein638720236 12.60200487 13.44947245 1.631 down 0.0641 RRSL_03400 o Hypothetical Protein638720239 13.66365487 13.93414745 1.093 down 0.653 RRSL_03403 o Hypothetical Protein638720240 7.639154869 7.998122449 1.162 down 0.448 RRSL_03404 o Transglutaminase-like enzymes, putative cysteine proteases638720241 7.971829869 8.130072449 1.011 down 0.948 RRSL_03406 o Hypothetical Protein638720242 10.96505487 11.24299745 1.099 down 0.514 RRSL_03407 o MoxR protein638720243 9.878829869 9.779447449 1.181 up 0.41 RRSL_03408 o Transcriptional regulator, TetR family638720244 9.678154869 9.940297449 1.087 down 0.473 RRSL_03409 o Probable transmembrane transporter protein, MFS family638720251 6.944154869 7.293847449 1.155 down 0.605 RRSL_03416 o Hypothetical Protein638720252 8.612254869 8.000397449 1.685 up 0.199 RRSL_03417 o Ferrichrome-iron receptor638720253 9.617904869 8.071422449 3.222 up 0.0582 RRSL_03418 o Hypothetical Protein638720256 9.880854869 9.508047449 1.428 up 0.463 RRSL_03422 o 6-carboxyhexanoate--CoA ligase( EC:6.2.1.14 )638720257 10.49370487 10.36347245 1.207 up 0.26 RRSL_03423 o Transcriptional regulator, GntR family638720258 8.589354869 8.423047449 1.237 up 0.355 RRSL_03424 o Arabinose efflux permease638720259 9.737129869 10.22622245 1.272 down 0.151 RRSL_03425 o Hypothetical cytosolic protein638720260 9.820004869 10.01934745 1.04 down 0.847 RRSL_03426 o Hypothetical cytosolic protein638720262 8.527904869 8.816947449 1.107 down 0.579 RRSL_03428 o Translation initiation inhibitor638720263 9.314329869 9.689072449 1.175 down 0.358 RRSL_03429 o Thioesterase( EC:3.1.2.- )638720264 8.120279869 8.749222449 1.401 down 0.0706 RRSL_03430 o benzoate-coenzyme A ligase( EC:6.2.1.25 )638720265 7.060379869 7.666072449 1.379 down 0.0353 RRSL_03431 o Acyl-CoA dehydrogenase, short-chain specific( EC:1.3.99.2 )638720266 8.280229869 8.797047449 1.296 down 0.00435 RRSL_03432 o 1,4-dihydroxy-2-naphthoate synthase/carnithine racemase/enoyl-CoA hydratase638720267 9.065479869 8.971047449 1.177 up 0.447 RRSL_03433 o Transcriptional regulator, MarR family638720268 8.063879869 8.998772449 1.732 down 0.00461 RRSL_03434 o Short chain dehydrogenase

638720269 7.910554869 8.552322449 1.414 down 0.0555 RRSL_03435 oprotein with COG1902, NADH: flavin oxidoreductase and COG0654, 2-polyprenyl-6-methoxyphenol hydroxylase & related FAD-dependent oxidoreducatse domains

638720270 8.414029869 8.334022449 1.166 up 0.245 RRSL_03436 o Hypothetical Protein638720271 9.836454869 9.320122449 1.577 up 0.233 RRSL_03437 o Beta-lactamase( EC:3.5.2.6 )638720277 11.48057987 11.81237245 1.14 down 0.543 RRSL_03018 o Hypothetical membrane spanning protein638720278 10.38787987 10.03387245 1.41 up 0.25 RRSL_03020 o Fosmidomycin resistance protein638720279 8.073879869 8.280422449 1.045 down 0.708 RRSL_03021 o Hypothetical Protein638720280 8.202129869 8.332647449 1.007 up 0.979 RRSL_03024 o putative sigma factor638720292 8.630904869 9.225697449 1.368 down 0.237 RRSL_03036 o Hypothetical Protein638720301 11.35925487 12.29692245 1.736 down 0.142 RRSL_03046 o Probable transporter, drug/metabolite (DMT) superfamily638720302 8.716354869 9.139672449 1.215 down 0.224 RRSL_03047 o Transcriptional regulator, AraC family638720311 11.88285487 12.51857245 1.408 down 0.107 RRSL_03056 o Hypothetical Protein638720312 8.416704869 7.880522449 1.599 up 0.126 RRSL_03057 o Probable outer membrane cation efflux protein638720313 8.439604869 8.076372449 1.419 up 0.208 RRSL_03058 o Probable transmembrane cation efflux system protein638720314 9.333404869 8.217347449 2.391 up 0.103 RRSL_03059 o Transmembrane cation efflux system638720315 10.70860487 10.64034745 1.156 up 0.585 RRSL_03060 o Hypothetical Protein638720316 9.308379869 8.410547449 2.055 up 0.0525 RRSL_03061 o Hypothetical Protein638720318 7.694604869 8.207547449 1.293 down 0.127 RRSL_03063 o Hypothetical membrane spanning protein638720320 8.123104869 8.652147449 1.307 down 0.216 RRSL_03066 o transcriptional regulator638720325 9.057554869 8.669822449 1.443 up 0.0899 RRSL_03071 o pilK PilK( EC:2.1.1.80 )638720326 10.53002987 9.743022449 1.903 up 0.0656 RRSL_03073 o Hypothetical Protein638720327 8.692954869 8.789297449 1.031 up 0.747 RRSL_03074 o RNA polymerase ECF-type sigma factor638720330 12.37395487 13.42119745 1.873 down 0.00765 RRSL_03077 o Hypothetical Protein638720340 13.83495487 14.89574745 1.89 down 0.0541 RRSL_03089 o Hypothetical Protein638720343 9.863304869 10.97854745 1.963 down 0.00403 RRSL_03092 o probable transmembrane lipoprotein638720347 7.417279869 8.293497449 1.663 down 0.014 RRSL_03095 o Hypothetical Protein638720348 10.79592987 11.28819745 1.275 down 0.255 RRSL_03098 o Guanine-hypoxanthine permease638720349 12.64902987 13.93812245 2.215 down 0.0904 RRSL_02927 o LSU ribosomal protein L34P638720353 10.62930487 11.13239745 1.284 down 0.093 RRSL_02931 o tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase638720355 8.492554869 8.400922449 1.175 up 0.581 RRSL_02934 o Protein tyrosine phosphatase( EC:3.1.3.48 )638720359 13.07902987 14.15907245 1.916 down 0.023 RRSL_02939 o SSU ribosomal protein S21P638720363 10.62760487 10.78772245 1.012 down 0.932 RRSL_02943 o AcrAB operon repressor638720398 8.761854869 8.214472449 1.612 up 0.053 RRSL_02979 o Folate transporter638720400 8.646404869 8.768347449 1.013 up 0.931 RRSL_02981 o Hypothetical Protein638720408 8.994654869 10.11189745 1.966 down 0.00241 RRSL_02990 o Low-affinity zinc transport protein638720414 9.338829869 10.14917245 1.589 down 0.0113 RRSL_02996 o CbiX protein / Precorrin-8X methylmutase( EC:5.4.1.2 )638720415 10.25192987 11.14462245 1.682 down 0.00287 RRSL_02997 o Hypothetical Protein638720425 9.883154869 10.53724745 1.426 down 0.0356 RRSL_03009 o Polysaccharide acetyltransferase( EC:2.3.1.- )638720429 11.62405487 12.58004745 1.758 down 0.00192 RRSL_03191 o Thiol-disulfide isomerase and thioredoxins638720431 14.08112987 13.84557245 1.298 up 0.212 RRSL_03193 o transposase remnant protein638720431 14.08112987 13.84557245 1.298 up 0.212 RRSL_03193 o transposase remnant protein638720431 14.08112987 13.84557245 1.298 up 0.212 RRSL_03193 o transposase remnant protein638720431 14.08112987 13.84557245 1.298 up 0.212 RRSL_03193 o transposase remnant protein638720448 10.16775487 10.97419745 1.585 down 0.0212 RRSL_03211 o Beta-ureidopropionase( EC:3.5.1.6 )638720464 11.34362987 11.18439745 1.231 up 0.154 RRSL_03229 o Hypothetical Protein638720465 8.327604869 8.772997449 1.234 down 0.144 RRSL_03230 o Hypothetical Protein638720466 10.49990487 10.59217245 1.034 up 0.799 RRSL_03231 o Hypothetical Protein638720467 10.12162987 10.42027245 1.114 down 0.465 RRSL_03232 o Hypothetical Protein638720468 12.24807987 12.36992245 1.013 up 0.892 RRSL_03233 o pilE PilE638720476 10.48530487 11.33817245 1.637 down 0.0324 RRSL_03242 o Hydrogen peroxide-inducible genes activator638720479 8.161454869 8.792647449 1.403 down 0.0406 RRSL_03245 o Outer membrane porin protein 32 precursor638720480 10.76752987 11.30002245 1.311 down 0.0197 RRSL_03246 o Transporter, drug/metabolite exporter family638720481 8.205004869 8.729922449 1.304 down 0.208 RRSL_03247 o Aldehyde dehydrogenase( EC:1.2.1.3 )638720482 7.812829869 8.177547449 1.167 down 0.493 RRSL_03248 o Dihydrodipicolinate synthase( EC:4.2.1.52 )638720483 7.756004869 7.573797449 1.251 up 0.585 RRSL_03249 o Transporter, MFS superfamily638720484 7.672354869 7.611597449 1.15 up 0.571 RRSL_03250 o Oxidoreductase( EC:1.- )638720486 10.82002987 11.55359745 1.507 down 0.0233 RRSL_03252 o Transcriptional regulator, GntR family

638720491 7.650054869 7.181097449 1.526 up 0.3 RRSL_03257 o Transcriptional regulators, LysR family638720492 7.470004869 7.277572449 1.26 up 0.506 RRSL_03258 o Alanine racemase( EC:5.1.1.1 )638720501 8.358529869 8.571122449 1.05 down 0.725 RRSL_02240 o Hypothetical Protein638720502 11.76590487 10.92772245 1.972 up 0.0981 RRSL_02241 o Hypothetical Protein638720503 11.11097987 10.76719745 1.4 up 0.272 RRSL_02242 o Hypothetical Protein638720504 10.78117987 11.01824745 1.068 down 0.659 RRSL_02243 o 1-aminocyclopropane-1-carboxylate deaminase( EC:3.5.99.7,EC:4.1.99.4 )638720505 7.829754869 7.628122449 1.268 up 0.106 RRSL_02244 o 3-hydroxyisobutyryl-CoA hydrolase( EC:3.1.2.4 )638720506 8.184079869 7.540097449 1.723 up 0.021 RRSL_02245 o 3-hydroxybutyryl-CoA dehydratase( EC:4.2.1.55 )638720510 8.628254869 8.315047449 1.37 up 0.0663 RRSL_02249 o Transcriptional regulator, AraC family638720515 9.488954869 9.954747449 1.251 down 0.141 RRSL_02254 o Transcriptional regulator, MarR family638720516 9.377629869 9.434897449 1.06 up 0.511 RRSL_02255 o corA CorA638720517 8.817254869 9.211247449 1.191 down 0.0417 RRSL_02256 o DNA-3-methyladenine glycosylase( EC:3.2.2.20 )638720518 9.836804869 9.379097449 1.515 up 0.208 RRSL_02257 o Transporter, MFS superfamily638720519 8.213129869 8.131897449 1.167 up 0.445 RRSL_02258 o Hypothetical cytosolic protein638720521 7.916979869 8.987722449 1.904 down 0.00568 RRSL_02260 o oprM OprM638720522 8.716054869 8.906222449 1.034 down 0.833 RRSL_02262 o Acriflavin resistance plasma membrane protein638720523 7.189229869 7.983122449 1.571 down 0.0672 RRSL_02263 o Enoyl-CoA hydratase( EC:4.2.1.17 )638720525 6.269004869 6.903747449 1.407 down 0.0337 RRSL_02265 o Hypothetical exported protein638720526 9.713354869 7.963897449 3.709 up 0.073 RRSL_02266 o Putative periplasmic protein638720527 7.738804869 7.442447449 1.354 up 0.168 RRSL_02267 o Putative periplasmic protein638720529 10.29030487 10.45617245 1.016 down 0.941 RRSL_02269 o metR MetR638720530 9.822729869 9.863772449 1.072 up 0.749 RRSL_02270 o Pyridoxamine 5'-phosphate oxidase( EC:1.4.3.5 )638720531 9.703429869 9.890722449 1.032 down 0.902 RRSL_02271 o Hypothetical Protein638720534 8.959004869 9.904347449 1.745 down 0.0271 RRSL_02274 o Trimethylamine dehydrogenase( EC:1.5.8.2 )638720536 10.13412987 10.27212245 1.002 up 0.991 RRSL_02276 o Transporter, drug/metabolite exporter family638720543 8.603104869 7.857672449 1.849 up 0.0276 RRSL_02283 o nahR NahR638720544 8.282329869 9.086997449 1.583 down 0.0289 RRSL_02285 o RtcB protein638720547 10.01120487 10.10617245 1.032 up 0.833 RRSL_02289 o Transcriptional regulator, IclR family638720555 11.99252987 11.27999745 1.807 up 0.0374 RRSL_02865 o Disulfide bond formation protein B638720556 8.457979869 9.239022449 1.557 down 0.000239 RRSL_02867 o polyl aminopeptidase( EC:3.4.11.5 )638720557 9.536179869 9.780347449 1.073 down 0.701 RRSL_02868 o hypothetical protein638720558 10.04137987 10.58749745 1.323 down 0.0971 RRSL_02870 o 3-oxoacyl-[acyl-carrier-protein] synthase III( EC:2.3.1.41 )638720559 10.63730487 11.23294745 1.369 down 0.118 RRSL_02872 o Putative permease638720560 9.440729869 10.03444745 1.367 down 0.111 RRSL_02873 o Fimbriae V protein638720562 8.888679869 8.847822449 1.134 up 0.628 RRSL_02876 o oxidoreductase, aldo/keto reductase family638720563 9.560379869 8.860422449 1.792 up 0.0667 RRSL_02877 o Bicyclomycin resistance protein638720565 8.654454869 8.629797449 1.122 up 0.644 RRSL_02879 o ABC transport system substrate-binding protein638720566 7.682704869 7.960647449 1.099 down 0.613 RRSL_02882 o Aconitate hydratase( EC:4.2.1.3 )638720567 7.456079869 8.257947449 1.58 down 0.0882 RRSL_02881 o hypothetical protein638720571 10.19145487 10.75879745 1.343 down 0.261 RRSL_02886 o hypothetical protein638720579 8.952054869 9.715572449 1.538 down 0.0319 RRSL_02893 o hypothetical protein638720580 11.43385487 11.80029745 1.168 down 0.169 RRSL_02894 o hypothetical protein638720598 10.40185487 10.71964745 1.129 down 0.555 RRSL_02914 o Transcriptional regulator, AraC family638720602 10.90015487 10.21764745 1.77 up 0.0353 RRSL_02918 o Mannose-6-phosphate isomerase( EC:5.3.1.8 )638720604 9.897229869 10.20329745 1.12 down 0.307 RRSL_02920 o hypothetical protein638720605 9.965104869 9.938047449 1.124 up 0.248 RRSL_02921 o hypothetical protein638720612 9.332529869 10.00967245 1.449 down 0.0475 RRSL_02787 o ATP-dependent DNA helicase rep( EC:3.6.1.- )638720617 10.02727987 9.278672449 1.853 up 0.0293 RRSL_02792 o solI SolI638720618 8.767904869 8.004622449 1.872 up 0.147 RRSL_02793 o Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638720620 8.515954869 7.973597449 1.606 up 0.119 RRSL_02795 o Pyruvate kinase( EC:2.7.1.40 )638720621 7.488329869 7.137797449 1.406 up 0.168 RRSL_02796 o Glycerate dehydrogenase / Hydroxypyruvate reductase( EC:1.1.1.29,EC:1.1.1.81 )638720622 8.609204869 7.739322449 2.016 up 0.103 RRSL_02797 o 2-hydroxy-3-oxopropionate reductase( EC:1.1.1.60 )638720623 9.016579869 7.974447449 2.271 up 0.119 RRSL_02798 o Hydroxypyruvate isomerase( EC:5.3.1.22 )638720624 8.405654869 7.730547449 1.761 up 0.184 RRSL_02799 o Glyoxylate carboligase( EC:4.1.1.47 )638720626 9.658054869 9.801122449 1 down 0.998 RRSL_02801 o Hypothetical Protein638720627 10.51010487 10.14899745 1.416 up 0.334 RRSL_02802 o Transcriptional regulator638720654 8.919679869 9.808097449 1.677 down 0.0295 RRSL_02832 o Hypothetical Protein

638720656 10.98182987 11.41674745 1.225 down 0.248 RRSL_02835 o Hypothetical membrane spanning protein638720664 12.59755487 13.06489745 1.253 down 0.266 RRSL_02844 o Hypothetical membrane spanning protein638720665 8.039054869 8.476197449 1.227 down 0.0688 RRSL_02845 o Hypothetical Protein638720666 10.00260487 9.979347449 1.121 up 0.508 RRSL_02846 o Hypothetical Protein638720667 11.02567987 11.28674745 1.086 down 0.631 RRSL_02847 o Hypothetical Protein638720668 9.330729869 9.467447449 1.003 up 0.983 RRSL_02848 o putative type-4 fimbrial pilin related signal peptide protein638720671 7.853529869 7.766872449 1.171 up 0.523 RRSL_02850 o pilX PilX638720672 9.183079869 9.118422449 1.153 up 0.475 RRSL_02851 o PILI ASSEMBLY PROTEIN, PilY1638720675 8.824629869 8.575947449 1.31 up 0.202 RRSL_02854 o Multidrug resistance protein B638720676 7.273804869 7.246747449 1.124 up 0.515 RRSL_02855 o Hypothetical Protein638720682 11.46302987 12.34347245 1.668 down 0.00698 RRSL_02715 o ApaG protein638720708 11.39497987 11.70019745 1.12 down 0.539 RRSL_02741 o Hypothetical transmembrane protein638720765 8.183679869 9.094522449 1.704 down 0.121 RRSL_02055 o Hypothetical Protein638720774 16.67472987 16.32957245 1.401 up 0.000593 RRSL_02065 o cbhA CbhA638720783 9.804104869 10.18362245 1.179 down 0.329 RRSL_02076 o Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638720789 8.089679869 8.091497449 1.101 up 0.474 RRSL_02082 o Hypothetical protein638720790 9.568829869 9.307622449 1.322 up 0.0966 RRSL_02083 o probable two-component response regulator638720791 7.964779869 8.312447449 1.153 down 0.595 RRSL_02084 o Two component system histidine kinase( EC:2.7.3.- )638720799 10.99980487 11.56219745 1.338 down 0.244 RRSL_02093 o putative acyl-CoA transferases/carnitine dehydratase638720801 9.428629869 8.931822449 1.556 up 0.134 RRSL_02096 o Hypothetical membrane associated protein638720802 8.770654869 8.690422449 1.166 up 0.292 RRSL_02097 o Hypothetical Protein638720810 8.401579869 7.826547449 1.643 up 0.0556 RRSL_02105 o Probable transmembrane methyl-accepting chemotaxis protein638720817 8.680354869 8.105147449 1.643 up 0.0719 RRSL_02298 o Hypothetical Protein638720821 10.39965487 11.37069745 1.776 down 0.0539 RRSL_02302 o Hypothetical Protein638720822 11.22512987 11.13152245 1.177 up 0.118 RRSL_02303 o Hypothetical Protein638720823 12.44825487 11.59939745 1.986 up 0.00191 RRSL_02304 o Hypothetical Protein638720826 10.42920487 10.45332245 1.084 up 0.821 RRSL_02307 o Hypothetical Protein638720827 9.783504869 9.323922449 1.517 up 0.104 RRSL_02308 o Thiosulfate sulfurtransferase( EC:2.8.1.1 )638720828 8.065704869 8.020247449 1.138 up 0.198 RRSL_02309 o fliK FliK638720829 8.110154869 7.839647449 1.33 up 0.146 RRSL_02310 o fliI FliI( EC:3.6.3.14 )638720832 8.957829869 8.279697449 1.765 up 0.097 RRSL_02313 o fliF FliF638720835 7.632929869 7.383697449 1.311 up 0.217 RRSL_02316 o Hypothetical protein638720836 7.823604869 8.051347449 1.061 down 0.815 RRSL_02317 o Transcriptional regulator, MarR family638720841 9.749429869 10.26137245 1.292 down 0.00611 RRSL_02322 o Transcriptional regulator, luxR family638720842 9.375879869 9.005297449 1.426 up 0.0555 RRSL_02323 o Signal transduction protein EAL638720844 9.760654869 9.153872449 1.68 up 0.136 RRSL_02325 o fliM FliM638720845 9.059004869 8.375397449 1.771 up 0.00182 RRSL_02326 o fliN FliN638720849 8.563104869 7.723347449 1.974 up 0.0129 RRSL_02330 o fliR FliR638720850 10.83017987 10.82682245 1.105 up 0.343 RRSL_02333 o Hypothetical protein638720852 8.999279869 8.358647449 1.719 up 0.0392 RRSL_02335 o flgK FlgK638720855 8.544929869 8.450822449 1.177 up 0.364 RRSL_02338 o flgH FlgH638720857 11.01607987 10.28504745 1.831 up 0.0519 RRSL_02340 o flgF FlgF638720858 11.80267987 11.21819745 1.654 up 0.0901 RRSL_02341 o flgE FlgE638720861 9.693279869 9.269272449 1.48 up 0.0338 RRSL_02344 o flgB FlgB638720862 9.255054869 8.993722449 1.322 up 0.183 RRSL_02345 o flgA FlgA638720863 10.88835487 10.34559745 1.607 up 0.061 RRSL_02346 o flgM FlgM638720864 10.41322987 9.687222449 1.824 up 0.013 RRSL_02347 o flgN FlgN638720865 9.389854869 8.673572449 1.812 up 0.0558 RRSL_02348 o narP NarP638720867 10.72267987 11.07094745 1.153 down 0.529 RRSL_02350 o Transcriptional regulator, GntR family638720868 12.73880487 12.58247245 1.229 up 0.45 RRSL_02351 o H-NS-like proteins638720871 10.73552987 10.36887245 1.422 up 0.291 RRSL_02354 o Hypothetical Protein638720874 9.311329869 10.12467245 1.592 down 0.151 RRSL_02358 o Hypothetical Protein638720875 7.815804869 7.617522449 1.265 up 0.42 RRSL_02359 o Hypothetical Protein638720876 9.520504869 8.914622449 1.678 up 0.0553 RRSL_02360 o Hypothetical Protein638720879 7.594254869 8.238347449 1.416 down 0.0977 RRSL_02365 o Hypothetical Protein638720889 10.53697987 10.21067245 1.383 up 0.168 RRSL_02377 o Hypothetical cytosolic protein638720904 9.445504869 10.29662245 1.635 down 0.0571 RRSL_02392 o Oxidoreductase sulfite:cytrochrome C oxidoreductase subunit A (sorAa)

638720908 8.916004869 9.217872449 1.117 down 0.757 RRSL_02396 o Hypothetical Protein638720974 11.06895487 11.78759745 1.491 down 0.00336 RRSL_02192 o Membrane-bound lytic murein transglycosylase D precursor( EC:3.2.1.- )638720993 7.884129869 8.702997449 1.599 down 0.0492 RRSL_02212 o Alpha,alpha-trehalose-phosphate synthase (UDP-forming)( EC:2.4.1.15 )638720994 8.196529869 8.205172449 1.096 up 0.597 RRSL_02213 o Hypothetical Protein638720995 10.87302987 11.11979745 1.075 down 0.541 RRSL_02214 o C-5 sterol desaturase( EC:1.3.- )638720997 9.304754869 8.727872449 1.645 up 0.103 RRSL_02217 o Hypothetical Protein638720999 8.968129869 9.245747449 1.098 down 0.479 RRSL_02219 o putative dinucleotide-utilizing enzyme638721000 9.205229869 10.00787245 1.581 down 0.0828 RRSL_02220 o Hypothetical Protein638721002 8.521354869 8.779697449 1.084 down 0.663 RRSL_02222 o Hypothetical Protein638721003 9.211279869 9.224422449 1.093 up 0.738 RRSL_02223 o Hypothetical Protein638721004 7.165254869 7.209222449 1.07 up 0.635 RRSL_02224 o Methylamine utilization protein mauG precursor638721005 11.57315487 12.89419745 2.264 down 0.0552 RRSL_02225 o Hypothetical Protein638721009 8.501404869 8.279222449 1.286 up 0.0391 RRSL_02229 o Hypothetical Protein638721010 9.301779869 10.33974745 1.861 down 0.0321 RRSL_02230 o Sensor protein glpS( EC:2.7.3.- )638721012 9.629779869 10.04237245 1.206 down 0.132 RRSL_02232 o Hypothetical Protein638721013 10.16162987 11.11259745 1.752 down 0.00225 RRSL_02233 o livF LivF638721014 9.071904869 9.963797449 1.682 down 0.0583 RRSL_02234 o livG LivG638721015 10.88320487 11.65559745 1.548 down 0.114 RRSL_02235 o livH LivH638721016 7.288479869 7.363797449 1.047 up 0.83 RRSL_03128 o L-idonate 5-dehydrogenase( EC:1.1.1.264 )638721020 9.113354869 9.169922449 1.06 up 0.779 RRSL_03123 o Outer membrane porin protein 32 precursor638721025 8.196779869 8.589822449 1.19 down 0.404 RRSL_03118 o Transcriptional regulator, MerR family638721027 9.074729869 8.292872449 1.896 up 0.0611 RRSL_03116 o L-threonine 3-dehydrogenase( EC:1.1.1.103 )638721032 8.829979869 8.099072449 1.83 up 0.0838 RRSL_03110 o Hypothetical Protein638721033 8.957529869 8.507597449 1.506 up 0.067 RRSL_03109 o Hypothetical Protein638721034 9.334579869 9.070172449 1.325 up 0.0953 RRSL_03108 o probable transmembrane glycosyl hydrolase638721038 7.538654869 7.632997449 1.033 up 0.892 RRSL_03103 o Transcriptional regulatory protein638721039 8.520079869 8.357322449 1.234 up 0.325 RRSL_03102 o hypothetical protein rs03064638721072 9.212104869 9.315972449 1.026 up 0.828 RRSL_00503 o prhR PrhR638721075 9.653679869 8.583697449 2.316 up 0.179 RRSL_03129 o Gluconate 5-dehydrogenase( EC:1.1.1.69 )638721076 6.977929869 7.340397449 1.165 down 0.423 RRSL_03130 o Gluconokinase( EC:2.7.1.12 )638721077 9.571879869 9.284822449 1.346 up 0.0616 RRSL_03131 o 2-hydroxyacid dehydrogenase( EC:1.1.1.- )638721078 9.231804869 8.905497449 1.383 up 0.191 RRSL_03132 o Demethylmenaquinone methyltransferase family638721079 9.389404869 8.747522449 1.721 up 0.149 RRSL_03133 o Aspartate aminotransferase( EC:2.6.1.1 )638721083 7.435179869 7.950247449 1.295 down 0.198 RRSL_03138 o Regulator of kinase autophosphorylation inhibitor638721084 7.601754869 8.123972449 1.301 down 0.153 RRSL_03139 o Hypothetical Protein638721085 7.984079869 8.937047449 1.754 down 0.00757 RRSL_03140 o Lactam utilization protein LAMB638721086 10.42037987 10.79982245 1.179 down 0.518 RRSL_03141 o Short chain dehydrogenase638721087 7.242629869 7.436172449 1.036 down 0.876 RRSL_03142 o Hypothetical Protein638721088 8.596554869 8.748572449 1.007 down 0.976 RRSL_03143 o Hypothetical Protein638721089 9.683379869 10.50447245 1.601 down 0.0191 RRSL_03144 o glnQ GlnQ638721090 10.97577987 11.65539745 1.451 down 0.0109 RRSL_03145 o ABC transporter amino acid-binding protein638721091 8.006954869 8.763247449 1.531 down 0.0125 RRSL_03146 o Hypothetical Protein638721092 8.447229869 8.936522449 1.272 down 0.264 RRSL_03147 o Formate acetyltransferase( EC:2.3.1.54 )638721095 13.91062987 13.48977245 1.476 up 0.249 RRSL_03151 o hpiS HpiS638721098 15.70950487 16.67229745 1.766 down 0.00157 RRSL_03154 o Outer membrane porin protein 32 precursor638721099 11.12930487 10.35789745 1.883 up 0.0434 RRSL_03155 o Hypothetical Protein638721100 9.094854869 9.817022449 1.495 down 0.245 RRSL_03156 o Carboxypeptidase G2 precursor( EC:3.4.17.11 )638721103 11.02362987 10.63717245 1.442 up 0.00593 RRSL_03161 o Probable hemagglutinin-related protein638721104 7.850854869 8.027997449 1.024 down 0.927 RRSL_03162 o putative hemolysin activating-like protein638721105 8.906804869 8.326347449 1.649 up 0.132 RRSL_03164 o Hemolysin activator protein precursor638721109 10.96532987 11.33104745 1.167 down 0.332 RRSL_03168 o Hypothetical Protein638721111 10.14302987 10.02369745 1.198 up 0.469 RRSL_03170 o Transcriptional regulatory protein638721112 9.611879869 9.952447449 1.147 down 0.331 RRSL_03171 o transmembrane protein, hypothetical638721113 9.497229869 9.985172449 1.271 down 0.319 RRSL_03172 o TRANSMEMBRANE LIPOPROTEIN, tadD2638721114 10.74370487 10.81507245 1.049 up 0.708 RRSL_03173 o TRANSMEMBRANE TIGHT ADHERENCE TADC RELATED PROTEIN; tadC2638721115 9.637729869 9.991147449 1.158 down 0.431 RRSL_03174 o TRANSMEMBRANE PILUS ASSEMBLY PROTEIN: TadB2638721117 10.83355487 11.23942245 1.2 down 0.395 RRSL_03176 o PUTATIVE PILUS ASSEMBLY PROTEIN: CpaE2

638721118 11.72520487 11.79779745 1.049 up 0.793 RRSL_03177 o GspD-related protein; CpaC2638721119 10.54827987 11.34147245 1.57 down 0.134 RRSL_03178 o SIGNAL PEPTIDE HYPOTHETICAL; CpaB2638721120 12.33605487 12.87599745 1.317 down 0.252 RRSL_03179 o TRANSMEMBRANE HYPOTHETICAL; TadG2638721121 16.00472987 15.52992245 1.533 up 0.00508 RRSL_03180 o PROBABLE PREPILIN PEPTIDASE TRANSMEMBRANE PROTEIN; CpaA2638721122 15.85547987 15.09129745 1.873 up 0.000188 RRSL_03181 o putative pilin protein638721123 8.645879869 8.913047449 1.09 down 0.536 RRSL_03182 o putative hemagglutinin-related transmembrane protein638721125 11.77702987 11.90977245 1.006 up 0.982 RRSL_03185 o heme:hemopexin-binding protein638721126 13.24755487 13.21104745 1.131 up 0.465 RRSL_03186 o putative transcription regulator protein638721128 9.053454869 9.094247449 1.072 up 0.697 RRSL_02107 o Porin638721170 11.07322987 10.55269745 1.582 up 0.103 RRSL_02150 o Transcriptional regulator, RpiR family638721182 10.20857987 9.427547449 1.895 up 0.17 RRSL_02162 o 5-dehydro-2-deoxygluconokinase( EC:2.7.1.92 )638721189 10.90305487 10.33452245 1.636 up 0.0134 RRSL_02514 o hypothetical protein638721194 9.841629869 10.22999745 1.186 down 0.624 RRSL_02519 o probable transmembrane638721195 8.373354869 8.698922449 1.135 down 0.428 RRSL_02520 o Probable outer membrane drug efflux lipoprotein638721196 7.375129869 7.340447449 1.13 up 0.534 RRSL_02521 o Acriflavin resistance periplasmic protein638721197 7.788429869 7.630572449 1.23 up 0.437 RRSL_02522 o transmembrane transport protein638721198 7.641729869 7.156272449 1.544 up 0.069 RRSL_02523 o Aromatic compound transporter, MFS family638721199 8.236129869 7.813722449 1.478 up 0.112 RRSL_02525 o Outer membrane porin protein 32 precursor638721200 9.227829869 9.172622449 1.146 up 0.062 RRSL_02526 o Transcriptional regulators, LysR family638721202 9.230829869 9.690897449 1.246 down 0.0399 RRSL_02528 o piperideine-6-carboxylate dehydrogenase( EC:1.2.1.- )638721203 8.602054869 8.708022449 1.025 up 0.875 RRSL_02529 o Oxidoreductase( EC:1.1.1.- )638721204 11.60582987 12.08864745 1.266 down 0.329 RRSL_02531 o O-acetylhomoserine sulfhydrylase / O-acetylserine sulfhydrylase( EC:4.2.99.10,EC:4.2.99.8 )638721206 11.68035487 12.77192245 1.931 down 0.0297 RRSL_02534 o hypothetical protein638721208 11.87545487 12.91974745 1.869 down 0.0104 RRSL_02536 o hypothetical protein638721210 11.09950487 12.01722245 1.712 down 0.0319 RRSL_02538 o asparagine transport system permease protein638721211 11.37390487 11.74144745 1.169 down 0.151 RRSL_02539 o Transporter638721212 11.71010487 12.33462245 1.397 down 0.00723 RRSL_02540 o ABC Transporter Amino Acid binding protein638721214 7.785779869 8.424622449 1.411 down 0.029 RRSL_02542 o Translation initiation inhibitor638721215 11.07785487 10.73812245 1.396 up 0.307 RRSL_02543 o Transporter638721226 10.17502987 9.141647449 2.258 up 0.164 RRSL_02556 o hypothetical protein638721235 8.641979869 7.802822449 1.973 up 0.0265 RRSL_02565 o transmembrane integral membrane protein638721236 7.520179869 8.079447449 1.335 down 0.043 RRSL_02566 o Transcriptional regulator, AraC family638721243 9.515379869 10.28462245 1.544 down 0.0311 RRSL_02449 o Urease gamma subunit( EC:3.5.1.5 )638721244 9.406879869 10.40892245 1.815 down 0.0218 RRSL_02450 o High-affinity nickel transport protein638721250 14.48902987 13.92239745 1.633 up 0.00592 RRSL_02456 o Hypothetical Protein638721254 11.47317987 11.27462245 1.265 up 0.0777 RRSL_02460 o Hypothetical protein638721255 13.58952987 13.98329745 1.19 down 0.167 RRSL_02461 o Glutathione S-transferase( EC:2.5.1.18 )638721256 8.474504869 8.642622449 1.018 down 0.887 RRSL_02462 o Acyl-CoA dehydrogenase( EC:1.3.99.- )638721257 10.27620487 9.160047449 2.391 up 0.0701 RRSL_02464 o paaI PaaI638721258 7.353429869 8.224622449 1.658 down 0.044 RRSL_02463 o Transcriptional regulators, LysR family638721260 8.656954869 8.139947449 1.578 up 0.0609 RRSL_02466 o Hypothetical Protein638721261 9.516904869 9.348472449 1.239 up 0.344 RRSL_02467 o Phosphotransferase638721262 8.416679869 8.691422449 1.096 down 0.532 RRSL_02468 o Phosphoglycerate mutase( EC:5.4.2.1 )638721263 9.380804869 9.749597449 1.17 down 0.121 RRSL_02469 o Enoyl-CoA hydratase( EC:4.2.1.17 )638721264 8.655054869 8.866247449 1.049 down 0.803 RRSL_02470 o 3-hydroxybutyryl-CoA dehydrogenase( EC:1.1.1.157 )638721303 10.80545487 11.10804745 1.117 down 0.366 RRSL_01731 o Hypothetical protein638721304 10.37067987 11.44039745 1.902 down 0.151 RRSL_01732 o Hypothetical Protein638721305 13.51010487 13.80239745 1.11 down 0.697 RRSL_01733 o Hypothetical cytosolic protein638721306 11.69187987 12.19269745 1.282 down 0.422 RRSL_01734 o Hypothetical cytosolic protein638721307 15.62912987 15.59534745 1.129 up 0.344 RRSL_01735 o Hypothetical Protein638721308 10.14965487 10.85399745 1.476 down 0.299 RRSL_01736 o Hypothetical protein638721309 9.882829869 10.61172245 1.502 down 0.104 RRSL_01737 o Hypothetical protein638721310 8.079154869 8.771922449 1.465 down 0.169 RRSL_01738 o quinoprotein dehydrogenase638721311 9.573679869 10.41277245 1.621 down 0.0898 RRSL_01739 o ClpB protein638721312 9.695029869 10.33489745 1.412 down 0.00379 RRSL_01740 o VgrG protein638721313 9.848929869 10.25269745 1.199 down 0.348 RRSL_01741 o Hypothetical Protein638721322 10.15270487 11.33839745 2.061 down 0.0646 RRSL_01750 o FenI

638721323 10.94000487 12.01757245 1.913 down 0.053 RRSL_01751 o Hypothetical protein638721325 11.07012987 11.97339745 1.695 down 0.0187 RRSL_01753 o Hypothetical Protein638721327 9.920629869 10.82784745 1.699 down 0.0247 RRSL_01755 o Hypothetical Protein638721328 10.26637987 11.27997245 1.83 down 0.108 RRSL_01756 o L-alanyl-D-glutamate peptidase( EC:3.4.- )638721329 11.22200487 12.26669745 1.869 down 0.0907 RRSL_01757 o Hypothetical Protein638721330 11.50815487 11.75917245 1.078 down 0.706 RRSL_01758 o VgrG protein638721336 8.362254869 9.462347449 1.943 down 0.0468 RRSL_01766 o Aspartate aminotransferase( EC:2.6.1.1 )638721339 6.826854869 7.471872449 1.417 down 0.0571 RRSL_01769 o Hypothetical cytosolic protein638721341 13.44442987 13.11107245 1.389 up 0.26 RRSL_01772 o Hypothetical Protein638721342 13.95952987 13.75064745 1.275 up 0.0761 RRSL_01773 o Cation transporters638721344 11.80347987 11.91554745 1.02 up 0.848 RRSL_01775 o Protein Translation Elongation Factor G (EF-G)638721345 15.82910487 16.52852245 1.471 down 0.000587 RRSL_01831 o SSU ribosomal protein S10P638721352 15.23480487 15.86492245 1.402 down 0.0278 RRSL_01838 o SSU ribosomal protein S3P638721356 16.00700487 16.55407245 1.324 down 0.0035 RRSL_01842 o LSU ribosomal protein L14P638721357 16.39122987 16.89529745 1.285 down 0.00433 RRSL_01843 o LSU ribosomal protein L24P638721358 16.25965487 16.65227245 1.189 down 0.00262 RRSL_01844 o LSU ribosomal protein L5P638721359 14.79807987 15.47757245 1.451 down 0.0229 RRSL_01845 o SSU ribosomal protein S14P638721368 16.50157987 16.68949745 1.032 down 0.266 RRSL_01854 o LSU ribosomal protein L36P638721370 16.14635487 16.60954745 1.249 down 0.00649 RRSL_01856 o SSU ribosomal protein S11P638721388 8.536029869 9.404422449 1.654 down 0.0146 RRSL_01875 o Frataxin family protein638721427 13.87027987 13.92347245 1.063 up 0.26 RRSL_01915 o Myo-inositol-1(or 4)-monophosphatase( EC:3.1.3.25 )638721434 9.809754869 10.34647245 1.314 down 0.0581 RRSL_01923 o 2,5-diketo-D-gluconic acid reductase( EC:1.1.1.274 )638721435 8.168454869 7.497172449 1.756 up 0.233 RRSL_01924 o Transmembrane efflux protein638721436 7.509779869 7.273247449 1.299 up 0.212 RRSL_01925 o Transcriptional regulators, LysR family638721438 9.525904869 10.39579745 1.656 down 0.00723 RRSL_01927 o Hypothetical Protein638721449 8.730854869 9.031022449 1.116 down 0.552 RRSL_01940 o Lipoprotein638721450 7.170879869 7.405447449 1.066 down 0.655 RRSL_01941 o Hypothetical Protein638721501 12.28807987 13.24339745 1.757 down 0.0725 RRSL_02606 o Integration host factor alpha-subunit638721526 9.193504869 9.491122449 1.114 down 0.692 RRSL_01674 o Transporter, drug/metabolite exporter family638721544 9.838679869 10.55527245 1.489 down 0.042 RRSL_01692 o 1,4-alpha-glucan branching enzyme( EC:2.4.1.18 )638721549 7.453129869 7.149722449 1.361 up 0.393 RRSL_01697 o hmuS HmuS638721550 8.574404869 7.929422449 1.725 up 0.24 RRSL_01698 o Hemin receptor638721555 9.501054869 8.895422449 1.678 up 0.0679 RRSL_01704 o Hypothetical Protein638721556 7.611104869 8.708897449 1.94 down 0.00758 RRSL_01705 o probable transmembrane638721559 9.865504869 9.793972449 1.159 up 0.28 RRSL_01708 o Sensory transduction protein kinase( EC:2.7.3.- )638721560 10.44390487 9.925072449 1.58 up 0.0141 RRSL_01709 o Hypothetical Protein638721561 7.156679869 7.030422449 1.204 up 0.275 RRSL_01710 o Probable aerotaxis receptor (aer2)638721562 8.257779869 8.738197449 1.264 down 0.105 RRSL_01711 o Hypothetical Protein638721563 10.30297987 10.50234745 1.04 down 0.748 RRSL_01712 o Siderophore-interacting protein638721564 11.63582987 11.27294745 1.418 up 0.114 RRSL_01713 o Transcriptional regulator638721566 7.285529869 7.572872449 1.106 down 0.543 RRSL_01715 o Hypothetical Protein638721570 8.669379869 9.180197449 1.291 down 0.0634 RRSL_01719 o Acetyltransferase( EC:2.3.1.- )638721571 8.959554869 9.169997449 1.048 down 0.724 RRSL_01720 o Carboxypeptidase G2 precursor( EC:3.4.17.11 )638721576 8.655979869 8.223972449 1.488 up 0.412 RRSL_01725 o Hypothetical Protein638721577 7.929554869 7.436147449 1.553 up 0.23 RRSL_01726 o Hypothetical Protein638721579 9.639329869 9.505447449 1.21 up 0.654 RRSL_01728 o Hypothetical Protein638721586 9.115629869 9.610572449 1.277 down 0.317 RRSL_01784 o Hypothetical Protein638721594 11.03580487 11.23877245 1.043 down 0.854 RRSL_01793 o ABC transporter ATP-binding protein638721595 11.76557987 12.01024745 1.073 down 0.797 RRSL_01794 o Amino acid ABC transporter permease protein638721596 11.74697987 12.04119745 1.111 down 0.729 RRSL_01795 o ABC transporter amino acid-binding protein638721597 8.302804869 9.197572449 1.685 down 0.0224 RRSL_01796 o Transcriptional regulator, AsnC family638721598 13.35932987 12.51389745 1.982 up 0.113 RRSL_01797 o Ornithine cyclodeaminase( EC:4.3.1.12 )638721599 10.33805487 10.13954745 1.265 up 0.46 RRSL_01798 o Hypothetical protein638721600 10.34370487 10.41927245 1.046 up 0.83 RRSL_01799 o Phosphoglycolate phosphatase( EC:3.1.3.18 )638721601 7.264004869 7.999097449 1.508 down 0.0719 RRSL_01800 o Hypothetical Protein638721602 14.41375487 13.73284745 1.768 up 0.00651 RRSL_01801 o Hypothetical Protein

638721605 8.743229869 8.945022449 1.042 down 0.731 RRSL_01804 otranscriptional regulator transmembrane sensory transduction histidine kinase for Co, Zn, Cd resistance czcS( EC:2.7.3.- )

638721606 10.26775487 11.12004745 1.636 down 0.0486 RRSL_01806 o czcR CzcR638721611 11.46042987 12.66677245 2.091 down 0.0536 RRSL_01810 o Hypothetical protein638721612 9.444404869 10.26102245 1.596 down 0.159 RRSL_01812 o Probable Cobalt-zinc-cadmium outer membrane resistance protein (czcC)638721613 9.321779869 9.812422449 1.273 down 0.356 RRSL_01813 o czcB CzcB638721614 9.908104869 10.86342245 1.757 down 0.0145 RRSL_01814 o Cobalt-zinc-cadmium resistance protein (czcA)638721617 9.844629869 10.17039745 1.136 down 0.233 RRSL_01817 o Oxidoreductase D-3-phosphoglycerate dehydrogenase (ldhA)638721618 10.09195487 9.202522449 2.043 up 0.0625 RRSL_01818 o Hypothetical Protein638721620 8.870879869 8.214147449 1.739 up 0.247 RRSL_01820 o Bacteriophage N4 adsorption protein B638721621 7.548554869 7.448347449 1.182 up 0.478 RRSL_01821 o Hypothetical Protein638721623 8.338704869 8.244972449 1.177 up 0.37 RRSL_01823 o Probable UDP-N-acetylglucosamine 2-epimerase( EC:5.1.3.14 )638721624 7.909329869 8.042747449 1.005 up 0.975 RRSL_01824 o Hypothetical Protein638721625 10.68167987 10.29729745 1.44 up 0.0884 RRSL_01825 o Hypothetical Protein638721687 9.435654869 10.16084745 1.498 down 0.2 RRSL_01624 o Hypothetical Protein638721690 9.757554869 9.291297449 1.524 up 0.142 RRSL_01627 o plcN PlcN( EC:3.1.4.3 )638721696 10.85282987 8.451372449 5.828 up 0.0552 RRSL_01632 o Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase( EC:6.3.4.15 )638721697 7.964354869 8.435147449 1.256 down 0.414 RRSL_01634 o Bvg accessory factor638721715 13.07632987 13.30379745 1.061 down 0.398 RRSL_01654 o transcriptional regulator/response regulator, LuxR638721725 9.657879869 10.70937245 1.878 down 0.0052 RRSL_01664 o Iron(III) dicitrate-binding protein638721742 12.29112987 13.26542245 1.78 down 0.0266 RRSL_01539 o ClpB protein638721743 9.263629869 8.163997449 2.364 up 0.154 RRSL_01540 o Sulfate-binding protein638721744 11.41765487 10.20607245 2.554 up 0.0881 RRSL_01541 o FMN reductase( EC:1.5.1.29 )638721746 7.476879869 7.178097449 1.357 up 0.251 RRSL_01543 o Alkanesulfonates-binding protein638721747 7.926129869 7.624047449 1.36 up 0.324 RRSL_01544 o Alkanesulfonate monooxygenase( EC:1.14.14.5 )638721749 7.295804869 7.207847449 1.172 up 0.425 RRSL_01546 o Alkanesulfonates transport ATP-binding protein638721752 9.043704869 8.405497449 1.717 up 0.0266 RRSL_01549 o Hypothetical protein638721758 10.04080487 8.770497449 2.661 up 0.09 RRSL_01556 o Two-component sensor histidine kinase( EC:2.7.3.- )638721759 7.982579869 7.674897449 1.365 up 0.243 RRSL_01557 o Transcriptional regulatory protein638721780 9.157079869 8.546022449 1.685 up 0.0464 RRSL_01581 o AvrA homolog638721781 7.117954869 7.162897449 1.069 up 0.75 RRSL_01582 o Hypothetical Protein638721845 11.05187987 11.21162245 1.012 down 0.946 RRSL_02030 o DnrW638721851 14.32477987 14.65304745 1.138 down 0.355 RRSL_02035 o DnaK suppressor protein638721856 9.996604869 10.30432245 1.121 down 0.471 RRSL_02040 o Hypothetical Protein638721899 15.52622987 15.50374745 1.12 up 0.0563 RRSL_01357 o Hypothetical Protein638721901 13.55335487 12.86859745 1.773 up 0.0705 RRSL_01359 o Integral membrane protein (Rhomboid family)638721915 7.625254869 8.682022449 1.885 down 0.0173 RRSL_01376 o tlpA TlpA638721916 9.232904869 9.808172449 1.35 down 0.0564 RRSL_01377 o Chloride channel protein638721928 10.22210487 10.30574745 1.041 up 0.798 RRSL_01963 o Metal-dependent amidase/aminoacylase/carboxypeptidase638721972 8.138629869 7.590122449 1.613 up 0.0712 RRSL_01122 o Isopentenyl transferase (Dimethylallyl transferase)638721974 9.449254869 9.043197449 1.461 up 0.143 RRSL_01124 o Luciferase-like monooxygenase( EC:1.14.- )638721976 8.285304869 7.451222449 1.966 up 0.184 RRSL_01126 o Lipoprotein638721977 8.478979869 7.995897449 1.541 up 0.106 RRSL_01127 o Hypothetical Protein638721979 8.086054869 7.934822449 1.225 up 0.259 RRSL_01130 o Lactoylglutathione lyase family protein638721980 7.421504869 7.232047449 1.258 up 0.263 RRSL_01131 o Hypothetical Protein638721981 7.619354869 7.761972449 1 down 0.997 RRSL_01132 o Aspartate aminotransferase( EC:2.6.1.1 )638721982 7.634179869 7.393497449 1.303 up 0.0592 RRSL_01133 o Demethylmenaquinone methyltransferase family638721983 7.825254869 7.878572449 1.063 up 0.784 RRSL_01134 o Demethylmenaquinone methyltransferase family638721984 8.096504869 8.222622449 1.01 up 0.94 RRSL_01135 o Transcriptional regulators, LysR family638722006 13.51112987 14.01102245 1.281 down 0.104 RRSL_01336 o Hypothetical Protein638722023 9.879804869 10.78147245 1.693 down 0.0115 RRSL_01354 o Predicted acyl-CoA transferases/carnitine dehydratase

638722024 14.70052987 14.61427245 1.171 up 0.0673 RRSL_01046 oUDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase( EC:1.1.1.-,EC:4.2.1.- )

638722026 13.77730487 14.57197245 1.572 down 0.0468 RRSL_01048 o probable transmembrane protein638722027 12.73892987 13.62519745 1.675 down 0.198 RRSL_01049 o UDP-bacillosamine synthetase( EC:2.6.1.- )638722028 14.11767987 14.84797245 1.503 down 0.129 RRSL_01050 o UDP-N-acetylbacillosamine 4-acetyltransferase( EC:2.3.1.- )638722029 15.78555487 16.14672245 1.164 down 0.4 RRSL_01051 o probable glycosyl transferase transmembrane protein

638722030 13.62402987 14.29467245 1.442 down 0.183 RRSL_01053 o putative acyl transferase protein638722031 13.17450487 13.89364745 1.492 down 0.163 RRSL_01054 o Oxidoreductase( EC:1.1.1.- )638722032 13.64085487 14.32999745 1.461 down 0.115 RRSL_01055 o Probable maltose O-acetyltransferase( EC:2.3.1.79 )638722033 13.52032987 13.83847245 1.13 down 0.567 RRSL_01056 o Glycosyltransferase( EC:2.4.1.- )638722039 13.63475487 14.55497245 1.715 down 0.0496 RRSL_01062 o epsP EpsP638722042 10.98045487 10.40382245 1.645 up 0.0434 RRSL_01066 o Hypothetical Protein638722043 12.03302987 11.24492245 1.905 up 0.0676 RRSL_01067 o Transcriptional regulatory protein638722046 11.74065487 12.29267245 1.328 down 0.466 RRSL_01071 o AWR family protein638722047 15.06047987 14.89004745 1.241 up 0.0238 RRSL_01072 o Transmembrane amino acid efflux protein638722050 7.631379869 7.110672449 1.582 up 0.0837 RRSL_01075 o Possible FyuA precursor638722052 7.027604869 7.287597449 1.085 down 0.784 RRSL_01078 o hypothetical protein638722065 8.906654869 9.312697449 1.201 down 0.379 RRSL_01263 o Alcohol dehydrogenase (NADP+)( EC:1.1.1.2,EC:1.1.1.255 )638722072 7.800954869 7.924397449 1.012 up 0.921 RRSL_01270 o Xanthine permease638722073 8.838129869 8.867297449 1.081 up 0.674 RRSL_01271 o Hydroxyatrazine hydrolase( EC:3.5.99.3 )638722083 11.21377987 11.95937245 1.519 down 0.262 RRSL_01281 o peptidoglycan binding protein (LysM domain)638722090 9.786429869 9.161222449 1.701 up 0.0573 RRSL_01015 o Hypothetical Protein638722098 10.39885487 10.67552245 1.098 down 0.729 RRSL_01023 o Nicotinamide phosphoribosyltransferase( EC:2.4.2.12 )638722099 10.61000487 11.20969745 1.373 down 0.00434 RRSL_01024 o nicotinamide-nucleotide adenylyltransferase / Nudix hydrolase( EC:2.7.7.1 )638722102 9.113004869 8.456722449 1.738 up 0.00346 RRSL_01028 o dTDP-glucose 4,6-dehydratase( EC:4.2.1.46 )638722106 7.772254869 7.191922449 1.649 up 0.0483 RRSL_01032 o oxoglutarate semialdehyde dehydrogenase( EC:1.2.1.-,EC:1.2.1.4 )638722111 11.28735487 11.20797245 1.165 up 0.383 RRSL_01037 o Transcriptional regulators, LysR family638722112 13.13482987 13.17679745 1.071 up 0.294 RRSL_01038 o Hypothetical Protein638722113 8.848254869 9.421672449 1.348 down 0.127 RRSL_01040 o Transporter, drug/metabolite exporter family638722114 8.156054869 8.131972449 1.121 up 0.663 RRSL_01041 o Probable drug efflux lipoprotein638722115 7.564154869 7.249147449 1.372 up 0.271 RRSL_01042 o Transmembrane drug efflux protein638722116 7.883429869 7.925997449 1.071 up 0.749 RRSL_01043 o Probable outer membrane drug efflux lipoprotein638722117 7.138104869 7.279722449 1 RRSL_01044 o Hypothetical Protein638722118 7.822079869 7.949147449 1.01 up 0.957 RRSL_01045 o Transcriptional regulator, TetR family638722163 7.939904869 7.780097449 1.232 up 0.255 RRSL_01491 o TauD / TfdA family dioxygenase638722184 10.66912987 10.85702245 1.032 down 0.859 RRSL_01513 o Pyridoxamine 5'-phosphate oxidase( EC:1.4.3.5 )638722187 10.35897987 10.52027245 1.013 down 0.925 RRSL_01516 o possible oxidoreductase transmembrane dehydrogenase638722188 10.90082987 10.38292245 1.579 up 0.0298 RRSL_01517 o dehydrogluconate dehydrogenase, large subunit( EC:1.1.99.4 )638722189 9.135029869 9.161897449 1.082 up 0.659 RRSL_01518 o dehydrogluconate dehydrogenase, cytochrome c subunit( EC:1.1.99.4 )638722224 10.34155487 10.35352245 1.094 up 0.68 RRSL_01309 o Transcriptional regulators, LysR family638722233 11.10242987 11.47992245 1.177 down 0.121 RRSL_01319 o ABC transporter ATP-binding protein638722269 10.82120487 11.08017245 1.084 down 0.492 RRSL_01482 o glycoprotein/polysaccharide metabolism638722284 9.540179869 10.25317245 1.485 down 0.00568 RRSL_01091 o Transcriptional regulator, ArsR family638722285 9.284504869 10.26877245 1.793 down 0.00303 RRSL_01092 o Hypothetical Protein638722286 8.361079869 8.686647449 1.135 down 0.363 RRSL_01093 o Transcriptional regulators, LysR family638722287 7.551879869 7.784722449 1.065 down 0.819 RRSL_01094 o Oxidoreductase( EC:1.1.1.- )638722288 8.262379869 8.456147449 1.036 down 0.855 RRSL_01095 o NADH:flavin oxidoreductases, Old Yellow Enzyme family638722289 7.999354869 8.264347449 1.089 down 0.721 RRSL_01096 o Pirin638722306 7.721704869 7.951772449 1.063 down 0.799 RRSL_00922 o Membrane-bound aldehyde dehydrogenase, large subunit( EC:1.2.99.3 )638722307 6.429854869 7.018797449 1.363 down 0.149 RRSL_00923 o Membrane-bound aldehyde dehydrogenase iron-sulfur protein( EC:1.2.99.3 )638722311 9.311104869 9.901947449 1.365 down 0.0167 RRSL_00928 o 2-isopropylmalate synthase( EC:4.1.3.12 )638722312 10.16952987 9.964747449 1.271 up 0.382 RRSL_00929 o Cadmium resistance regulatory protein638722313 8.212929869 9.040747449 1.608 down 0.112 RRSL_00930 o Lead, cadmium, zinc and mercury transporting ATPase( EC:3.6.3.- )638722315 8.657729869 9.057247449 1.195 down 0.307 RRSL_00932 o Universal stress protein family638722316 9.234354869 9.444072449 1.048 down 0.516 RRSL_00933 o Hypothetical Protein638722317 9.184279869 9.453097449 1.092 down 0.721 RRSL_00934 o Nitropropane dioxygenase / Trans-enoyl-CoA reductase family638722318 8.708304869 8.789747449 1.042 up 0.71 RRSL_00935 o Sensor protein baeS( EC:2.7.3.- )638722319 9.156254869 9.552722449 1.193 down 0.325 RRSL_00936 o Transcriptional regulator, two component response regulator638722323 9.758079869 10.59157245 1.615 down 0.0267 RRSL_00940 o Macrolide-efflux protein638722325 13.39532987 13.83469745 1.229 down 0.329 RRSL_00942 o Transcriptional repressor PadR638722326 9.555529869 10.23067245 1.447 down 0.101 RRSL_00943 o Transcriptional regulators, LysR family638722327 9.620804869 10.51769745 1.687 down 0.018 RRSL_00944 o Nitropropane dioxygenase / Trans-enoyl-CoA reductase family638722328 10.18777987 8.123822449 4.612 up 0.0708 RRSL_00945 o Hypothetical Protein

638722329 6.696604869 7.280247449 1.358 down 0.0343 RRSL_00946 o Hypothetical Protein638722331 8.959004869 8.444322449 1.576 up 0.0329 RRSL_00948 o Probable transmembrane methyl-accepting chemotaxis protein638722332 9.229829869 9.801247449 1.346 down 0.167 RRSL_00949 o Acetyltransferase( EC:2.3.1.- )638722333 10.06867987 10.78894745 1.493 down 0.275 RRSL_00950 o Hypothetical Protein638722336 8.659329869 8.422372449 1.3 up 0.322 RRSL_00812 o Hypothetical Protein638722338 8.524654869 9.622547449 1.94 down 0.0242 RRSL_00814 o Hypothetical Protein638722343 9.006379869 8.497197449 1.57 up 0.125 RRSL_00820 o Hypothetical Protein638722348 7.964229869 8.735272449 1.546 down 0.00833 RRSL_00825 o Hypothetical Protein638722349 9.683279869 8.813197449 2.016 up 0.0762 RRSL_00826 o Hypothetical protein638722350 9.247529869 8.870147449 1.433 up 0.0606 RRSL_00827 o Hypothetical Protein638722351 9.642504869 9.992922449 1.155 down 0.322 RRSL_00828 o Hypothetical protein638722352 10.67310487 10.69252245 1.088 up 0.796 RRSL_00829 o Hypothetical protein638722353 14.08530487 14.08412245 1.104 up 0.271 RRSL_00830 o Hypothetical Protein638722355 9.348029869 10.02619745 1.45 down 0.05 RRSL_00832 o Hypothetical cytosolic protein638722378 10.28712987 10.52954745 1.072 down 0.435 RRSL_00970 o Hypothetical cytosolic protein638722388 9.875779869 9.814822449 1.15 up 0.611 RRSL_00766 o Transcriptional regulators, LysR family638722389 7.662654869 8.197397449 1.313 down 0.105 RRSL_00767 o esterase( EC:3.1.- )638722390 9.391654869 9.948172449 1.333 down 0.0729 RRSL_00768 o NAD(P)H-dependent quinone reductase( EC:1.- )638722395 8.124579869 7.960347449 1.236 up 0.262 RRSL_00773 o Cell surface protein638722396 8.324104869 7.765172449 1.625 up 0.361 RRSL_00774 o Co-activator of prophage gene expression IbrA638722397 8.932804869 8.605722449 1.383 up 0.131 RRSL_00775 o Co-activator of prophage gene expression IbrB638722398 7.413354869 8.151197449 1.511 down 0.0369 RRSL_00776 o Transcriptional regulator, LacI family638722400 11.57482987 10.82304745 1.857 up 0.0511 RRSL_00778 o Glucarate/galactarate transporter638722431 8.740304869 8.313147449 1.483 up 0.255 RRSL_00704 o Hypothetical Protein638722444 10.84897987 10.93009745 1.042 up 0.754 RRSL_00891 o Hypothetical Protein638722445 9.050904869 9.361397449 1.124 down 0.647 RRSL_00892 o Transporter638722446 8.310854869 8.418097449 1.024 up 0.838 RRSL_00894 o Transcriptional regulators, LysR family638722447 8.329129869 8.756172449 1.218 down 0.522 RRSL_00895 o 4-hydroxybenzoate transporter638722448 9.315154869 9.749122449 1.224 down 0.261 RRSL_00896 o nahR NahR638722449 8.367454869 9.447347449 1.916 down 0.00987 RRSL_00897 o Ferredoxin--NAD(+) reductase( EC:1.18.1.3 )638722450 10.41070487 11.02529745 1.387 down 0.236 RRSL_00898 o Salicylate-5-hydroxylase large oxygenase component( EC:1.14.15.- )638722451 10.11067987 11.00902245 1.689 down 0.0962 RRSL_00899 o Hypothetical Protein638722452 9.562254869 10.52489745 1.766 down 0.0315 RRSL_00900 o Rieske-type ferredoxin638722453 9.905029869 10.85862245 1.755 down 0.0024 RRSL_00901 o Gentisate 1,2-dioxygenase( EC:1.13.11.4 )638722455 8.340404869 8.510172449 1.019 down 0.832 RRSL_00904 o Outer membrane porin protein 32 precursor638722478 8.820504869 9.938122449 1.966 down 0.0307 RRSL_01433 o phzF PhzF638722485 7.531479869 7.736697449 1.045 down 0.774 RRSL_01440 o Hypothetical Protein638722491 12.54527987 12.62679745 1.042 up 0.863 RRSL_01446 o Hypothetical Protein638722503 7.996779869 8.731272449 1.508 down 0.0141 RRSL_00988 o Phosphoglycerate mutase638722513 10.37152987 10.83322245 1.248 down 0.0725 RRSL_00999 o D-amino acid dehydrogenase small subunit( EC:1.4.99.1 )638722525 14.50735487 15.38984745 1.671 down 0.0124 RRSL_00865 o Protein Translation Elongation Factor G (EF-G)638722526 16.24072987 16.56024745 1.131 down 0.07 RRSL_00866 o SSU ribosomal protein S7P638722532 8.478904869 8.778897449 1.115 down 0.56 RRSL_00872 o Hypothetical exported protein638722546 16.72400487 16.97354745 1.077 down 0.118 RRSL_00885 o Protein Translation Elongation Factor Tu (EF-TU)638722550 10.07875487 10.85417245 1.551 down 0.107 RRSL_00657 o DNA integration/recombination/invertion protein638722573 10.92385487 10.23897245 1.773 up 0.00593 RRSL_00679 o Hypothetical Protein638722575 8.173679869 8.046722449 1.204 up 0.234 RRSL_00570 o Alkanesulfonates-binding protein (ssuA2)638722577 12.12617987 12.14699745 1.087 up 0.654 RRSL_00572 o Integral membrane protein638722578 8.764104869 8.901347449 1.003 up 0.987 RRSL_00573 o Putative lipoprotein638722581 8.855529869 8.701872449 1.227 up 0.0798 RRSL_00577 o romA RomA638722583 9.182504869 8.364047449 1.945 up 0.0675 RRSL_00579 o Probable flagellar protein (fleN)638722584 8.594354869 8.130572449 1.521 up 0.0252 RRSL_00580 o Probable flagellar biosynthesis protein (flhF)638722586 8.260754869 7.703722449 1.623 up 0.109 RRSL_00582 o Probable transmembrane flagellar biosynthetic protein (flhB)638722588 9.016679869 7.867822449 2.446 up 0.0632 RRSL_00584 o Transporter638722590 7.732804869 8.189947449 1.244 down 0.178 RRSL_00586 o Shikimate 5-dehydrogenase( EC:1.1.1.25 )638722591 9.581004869 8.992097449 1.659 up 0.0645 RRSL_00587 o Outer membrane porin protein 32 precursor638722592 8.188154869 7.996547449 1.259 up 0.218 RRSL_00588 o 3-dehydroshikimate dehydratase / 4-hydroxyphenylpyruvate dioxygenase( EC:1.13.11.27,EC:4.2.1.- )

638722601 9.288104869 10.37922245 1.931 down 0.0297 RRSL_00445 o Hypothetical Protein638722605 9.089779869 9.435122449 1.151 down 0.302 RRSL_00449 o Stringent starvation protein A638722608 8.917004869 10.05519745 1.995 down 0.00492 RRSL_00453 o Hypothetical Protein638722609 8.131929869 8.964322449 1.614 down 0.0123 RRSL_00454 o Chemotaxis motB protein638722610 10.50660487 11.03117245 1.303 down 0.2 RRSL_00455 o Hypothetical Protein638722611 9.913829869 10.57919745 1.437 down 0.211 RRSL_00456 o Hypothetical Protein638722612 12.52735487 12.48182245 1.138 up 0.242 RRSL_00457 o Hypothetical Protein638722613 12.06200487 12.72364745 1.433 down 0.215 RRSL_00458 o Hypothetical protein638722614 13.32030487 13.87427245 1.33 down 0.115 RRSL_00459 o 3'-hydroxymethylcephem-O-carbamoyltransferase( EC:2.1.3.- )638722615 11.38957987 11.98372245 1.368 down 0.0692 RRSL_00460 o Hypothetical Protein638722616 10.75040487 11.41447245 1.436 down 0.218 RRSL_00462 o carbamoyl transferase638722617 11.24535487 11.77629745 1.309 down 0.364 RRSL_00463 o Hypothetical Protein638722619 10.69372987 10.93062245 1.068 down 0.703 RRSL_00465 o Oxidoreductase( EC:1.1.1.- )638722621 9.899904869 10.02309745 1.012 up 0.933 RRSL_00468 o Two-component sensor histidine kinase( EC:2.7.3.- )638722622 10.24595487 10.30429745 1.059 up 0.721 RRSL_00469 o Transporter, drug/metabolite exporter family638722623 8.552904869 8.857472449 1.119 down 0.407 RRSL_00470 o Integral membrane protein638722624 7.699029869 8.292222449 1.367 down 0.0647 RRSL_00471 o Putative lactonase638722626 7.737379869 8.076147449 1.146 down 0.389 RRSL_00473 o NADH oxidase( EC:1.- )638722627 8.606429869 9.390972449 1.561 down 0.0278 RRSL_00474 o Mercuric resistance operon regulatory protein638722628 9.615629869 9.442322449 1.244 up 0.145 RRSL_00475 o pme Pme( EC:3.1.1.11 )638722629 11.96430487 11.72737245 1.3 up 0.122 RRSL_00476 o General secretion pathway protein D638722630 7.369529869 7.320522449 1.141 up 0.567 RRSL_00477 o Hypothetical Protein638722631 8.987779869 7.520622449 3.05 up 0.0863 RRSL_00478 o Hypothetical Protein638722632 7.287729869 7.797722449 1.29 down 0.157 RRSL_00479 o Hypothetical Protein638722633 6.940404869 7.048097449 1.023 up 0.879 RRSL_00480 o Hypothetical Protein638722634 7.576004869 7.597072449 1.087 up 0.795 RRSL_00481 o General secretion pathway protein E638722635 8.015779869 7.704147449 1.369 up 0.136 RRSL_00482 o General secretion pathway protein F638722636 9.358654869 8.620447449 1.84 up 0.164 RRSL_00483 o General secretion pathway protein G638722642 10.10885487 9.276997449 1.963 up 0.257 RRSL_00846 o Hypothetical Protein638722653 8.752029869 8.015122449 1.838 up 0.145 RRSL_00858 o 2',3'-cyclic-nucleotide 2'-phosphodiesterase / 3'-nucleotidase( EC:3.1.3.6,EC:3.1.4.16 )638722654 8.334429869 8.275872449 1.148 up 0.44 RRSL_00859 o Hypothetical Protein638722658 9.865329869 10.39419745 1.307 down 0.182 RRSL_00527 o Hypothetical Protein638722670 8.114429869 8.244197449 1.008 up 0.957 RRSL_00540 o Transporter638722671 10.28955487 8.321872449 4.315 up 0.0599 RRSL_00541 o ABC transporter permease protein638722673 9.465804869 8.829472449 1.714 up 0.109 RRSL_00543 o ABC transporter substrate-binding protein638722674 7.269879869 7.349372449 1.044 up 0.86 RRSL_00544 o Transcriptional regulator, LacI family638722675 9.217679869 9.647672449 1.221 down 0.0394 RRSL_00545 o Hypothetical protein638722680 10.17330487 10.40374745 1.063 down 0.508 RRSL_00742 o Spherulin 4 precursor638722681 8.382304869 8.357522449 1.122 up 0.375 RRSL_00743 o ATP/GTP binding protein638722689 8.087679869 7.662247449 1.481 up 0.0632 RRSL_00751 o oprM OprM638722693 13.55692987 13.93104745 1.174 down 0.445 RRSL_00755 o H-NS-like proteins638722705 7.513679869 7.900847449 1.185 down 0.445 RRSL_00644 o Hypothetical protein638722706 10.34637987 10.19364745 1.226 up 0.33 RRSL_0644_1 o Hypothetical Protein638722707 7.950054869 8.878222449 1.724 down 0.0362 RRSL_00645 o Hypothetical Protein638722712 7.878854869 7.544247449 1.391 up 0.0895 RRSL_00652 o Probable protein-glutamate methylesterase (cheB)( EC:3.1.1.61 )638722713 7.718604869 7.608747449 1.19 up 0.221 RRSL_00653 o Probable chemotaxis diamidase (cheD)638722714 8.559629869 7.959172449 1.672 up 0.0586 RRSL_00654 o Probable chemotaxis protein methyltransferase (cheR)638722722 11.90685487 12.37572245 1.254 down 0.0663 RRSL_00796 o signal peptide outer membrane protein W638722748 8.573429869 9.090947449 1.297 down 0.095 RRSL_00607 o ragA RagA638722775 11.26610487 11.92489745 1.431 down 0.244 RRSL_00367 o Glycine cleavage system transcriptional activator638722780 11.17065487 10.41072245 1.868 up 0.0419 RRSL_00372 o Cytochrome d ubiquinol oxidase subunit II( EC:1.10.3.- )638722781 7.908254869 8.075272449 1.017 down 0.901 RRSL_00373 o 2-dehydropantoate 2-reductase( EC:1.1.1.169 )638722782 7.460029869 7.941722449 1.265 down 0.264 RRSL_00374 o Hypothetical Protein638722783 9.498704869 8.164797449 2.78 up 0.109 RRSL_00375 o Translation initiation inhibitor638722784 9.551079869 9.370622449 1.25 up 0.357 RRSL_00376 o Right origin-binding protein638722785 7.568354869 7.803672449 1.067 down 0.604 RRSL_00377 o Hypothetical exported protein638722786 10.66370487 10.18857245 1.533 up 0.112 RRSL_00378 o Fosfomycin resistance protein

638722787 8.424279869 9.285547449 1.646 down 0.0513 RRSL_00379 o Hypothetical Protein638722788 9.628254869 9.921247449 1.11 down 0.33 RRSL_00380 o Hypothetical Protein638722791 7.745179869 8.125947449 1.18 down 0.47 RRSL_00383 o Sensory transduction protein kinase( EC:2.7.3.- )638722792 10.55275487 9.694222449 2 up 0.0981 RRSL_00384 o Multidrug resistance protein B638722793 11.01905487 10.37499745 1.723 up 0.154 RRSL_00386 o Transcriptional regulators, LysR family638722795 12.77667987 12.68534745 1.175 up 0.305 RRSL_00389 o Hypothetical Protein638722797 10.35275487 9.157197449 2.526 up 0.0947 RRSL_00391 o Hypothetical Protein638722800 11.28382987 11.75424745 1.255 down 0.0166 RRSL_00395 o Hypothetical Protein638722803 9.317454869 8.681747449 1.714 up 0.231 RRSL_00398 o hypothetical transmembrane protein638722818 7.186229869 7.141222449 1.138 up 0.445 RRSL_00415 o Dihydrodipicolinate synthetase/N-acetylneuraminate lyase (partial ORF)638722821 9.934404869 9.472522449 1.519 up 0.104 RRSL_00491 o Regulatory protein638722822 10.37467987 8.654522449 3.634 up 0.113 RRSL_00493 o Probable transmembrane methyl-accepting chemotaxis protein638722823 8.410954869 7.703672449 1.801 up 0.069 RRSL_00494 o Hypothetical Protein638722824 7.374929869 6.888022449 1.546 up 0.00906 RRSL_00495 o Hypothetical Protein638722838 11.34465487 11.21867245 1.203 up 0.0373 RRSL_00356 o 3-hydroxyisobutyryl-CoA hydrolase( EC:3.1.2.4 )638722842 8.055404869 7.802622449 1.314 up 0.0966 RRSL_00359 o Hypothetical Protein638722844 9.006304869 8.749922449 1.317 up 0.353 RRSL_00361 o Probable multidrug resistance protein A (emrA) MLYD family638722845 8.371904869 7.623722449 1.853 up 0.138 RRSL_00362 o Multidrug resistance protein B (emrB) MFS family638722846 9.229729869 10.07732245 1.631 down 0.0596 RRSL_00363 o tRNA pseudouridine synthase B( EC:4.2.1.70 )638722847 11.89497987 12.18507245 1.108 down 0.346 RRSL_00364 o Ribosome-binding factor A638722850 9.137179869 9.252597449 1.018 up 0.798 RRSL_00553 o Puromycin-sensitive aminopeptidase( EC:3.4.11.- )638722851 6.910079869 7.084672449 1.023 down 0.798 RRSL_00554 o Nitrogen regulatory protein P-II638722852 8.675479869 8.798872449 1.012 up 0.953 RRSL_00555 o Probable transmembrane cation efflux system638722853 7.804329869 7.825547449 1.087 up 0.655 RRSL_00556 o cation efflux protein638722854 6.688829869 6.967747449 1.099 down 0.244 RRSL_00557 o Probable outer membrane cation efflux system638722860 11.34785487 11.61384745 1.089 down 0.46 RRSL_00564 o Molecular chaperones (DnaJ family)638722861 7.847604869 8.772947449 1.721 down 0.0119 RRSL_00566 o hscC HscC638722862 9.405329869 9.179772449 1.289 up 0.0561 RRSL_00565 o mntH MntH638722863 11.28195487 12.23307245 1.752 down 0.115 RRSL_00567 o Hypothetical Protein638722872 8.401429869 8.186947449 1.28 up 0.169 RRSL_00620 o Hypothetical membrane spanning protein638722873 12.68855487 12.02962245 1.741 up 0.0312 RRSL_00621 o Hypothetical Protein638722874 8.418804869 7.813672449 1.678 up 0.0329 RRSL_00623 o Sensor protein( EC:2.7.3.- )638722875 9.589929869 9.114197449 1.534 up 0.0924 RRSL_00625 o Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638722876 9.801304869 8.123122449 3.53 up 0.0709 RRSL_00626 o livH LivH638722877 10.09322987 8.522072449 3.278 up 0.108 RRSL_00627 o livM LivM638722878 8.283254869 7.622872449 1.743 up 0.165 RRSL_00628 o livG LivG638722879 8.661579869 8.267322449 1.449 up 0.067 RRSL_00629 o livF LivF638722880 7.897254869 8.304822449 1.202 down 0.216 RRSL_00630 o Transcriptional regulators, LysR family638722881 9.120004869 8.562297449 1.623 up 0.0725 RRSL_00631 o Hypothetical protein638722882 8.793329869 8.710222449 1.168 up 0.449 RRSL_00632 o Chloride channel protein638722925 11.31215487 11.30389745 1.109 up 0.596 RRSL_00296 o Transcriptional regulator638722936 8.384929869 8.120047449 1.325 up 0.196 RRSL_00327 o ATP-dependent DNA helicase pcrA( EC:3.6.1.- )638722937 9.342079869 9.342097449 1.103 up 0.701 RRSL_00328 o Transporter638722938 9.166954869 8.831422449 1.392 up 0.236 RRSL_00329 o Hypothetical membrane spanning protein638722939 8.370754869 8.670847449 1.116 down 0.473 RRSL_00331 o Hypothetical Protein638722941 7.804504869 8.603472449 1.577 down 0.0278 RRSL_00333 o probable signal peptide638722942 9.277104869 9.660147449 1.182 down 0.441 RRSL_00334 o Hypothetical Protein638722944 7.979304869 8.240297449 1.086 down 0.53 RRSL_00337 o Transcriptional regulators, LysR family638722945 10.29872987 10.32034745 1.086 up 0.536 RRSL_00338 o Hypothetical Protein638722946 9.461304869 8.791647449 1.754 up 0.0132 RRSL_00339 o Acetyl-coenzyme A synthetase( EC:6.2.1.1 )638722947 8.789429869 9.057647449 1.091 down 0.536 RRSL_00340 o Hypothetical membrane spanning protein638722999 10.26860487 10.43509745 1.017 down 0.956 RRSL_00190 o Protocatechuate 3,4-dioxygenase beta chain( EC:1.13.11.3 )638723000 9.023404869 9.442672449 1.212 down 0.219 RRSL_00191 o Hypothetical Protein638723004 8.678054869 8.424497449 1.315 up 0.144 RRSL_00168 o Hypothetical Protein638723006 11.90647987 12.11909745 1.05 down 0.686 RRSL_00170 o Hypothetical Protein638723009 8.339804869 9.114372449 1.55 down 0.145 RRSL_00248 o Methyltransferase( EC:2.1.1.- )638723010 8.653479869 7.935697449 1.814 up 0.112 RRSL_00249 o Sensor protein uhpB( EC:2.7.3.- )

638723011 8.593979869 8.303472449 1.349 up 0.19 RRSL_00250 o Transcriptional regulatory protein638723012 8.461804869 7.803347449 1.741 up 0.116 RRSL_00251 o Hemagglutinin-related protein638723013 8.448004869 8.234922449 1.278 up 0.414 RRSL_00252 o Tetratricopeptide repeat family protein638723014 7.418429869 7.556272449 1.002 up 0.991 RRSL_00253 o Tetratricopeptide repeat family protein638723015 6.912204869 6.981497449 1.051 up 0.765 RRSL_00254 o Hypothetical Protein638723016 7.844979869 7.531647449 1.37 up 0.191 RRSL_00255 o Adenylylsulfate kinase( EC:2.7.1.25 )638723031 8.901729869 7.506947449 2.9 up 0.0832 RRSL_00193 o Hypothetical Protein638723032 7.985679869 8.235847449 1.078 down 0.752 RRSL_00194 o Acetylornithine aminotransferase( EC:2.6.1.11 )638723068 12.22592987 11.73279745 1.552 up 0.206 RRSL_00121 o 1,4-alpha-glucan branching enzyme( EC:2.4.1.18 )638723069 8.739504869 9.691497449 1.753 down 0.0057 RRSL_00122 o Trehalose synthase638723072 12.19290487 12.44997245 1.083 down 0.509 RRSL_00094 o VgrG protein638723073 10.03290487 10.93084745 1.689 down 0.177 RRSL_00095 o Hypothetical Protein638723074 10.30650487 11.15309745 1.63 down 0.146 RRSL_00096 o Hypothetical protein638723076 9.070654869 9.618222449 1.324 down 0.257 RRSL_00113 o Mercuric reductase( EC:1.16.1.1 )638723079 7.490854869 7.913397449 1.214 down 0.138 RRSL_00119 o Hypothetical Protein638723081 8.713404869 7.726622449 2.186 up 0.0652 RRSL_00125 o Hypothetical Protein638723082 7.818279869 7.508547449 1.367 up 0.217 RRSL_00126 o Vitamin B12 receptor638723087 11.40057987 11.00814745 1.448 up 0.0468 RRSL_00105 o Hypothetical protein638723101 9.777929869 10.83342245 1.884 down 0.00737 RRSL_00067 o Peptide synthetase638723102 9.238829869 9.845072449 1.379 down 0.107 RRSL_00068 o Hypothetical Protein638723103 9.611029869 9.810922449 1.041 down 0.837 RRSL_00069 o Hypothetical Protein638723118 9.645179869 8.832672449 1.937 up 0.0492 RRSL_00061 o Glycine cleavage system transcriptional activator638723126 7.758604869 8.791647449 1.854 down 0.0268 RRSL_00056 o Hypothetical Protein638723127 10.80257987 11.76697245 1.768 down 0.0793 RRSL_00051 o Hypothetical Protein638723128 6.789154869 6.808497449 1.088 up 0.595 RRSL_00052 o Hypothetical Protein638723130 9.925904869 10.64037245 1.487 down 0.242 RRSL_00080 o Hypothetical Protein638723137 10.63637987 10.93244745 1.112 down 0.736 RRSL_00040 o PhoP/Q-regulated protein PqaA638723147 11.56035487 12.35204745 1.569 down 0.00686 RRSL_00018 o Methyltransferase( EC:2.1.1.- )638723149 7.733254869 8.272147449 1.316 down 0.197 RRSL_00044 o D-amino acid dehydrogenase small subunit( EC:1.4.99.1 )638723151 9.647629869 9.848172449 1.041 down 0.876 RRSL_00011 o Hemolysin activator protein precursor638723152 10.92965487 10.31392245 1.69 up 0.00567 RRSL_00008 o integral membrane acetyltransferase638718741 7.608054869 8.263422449 1.427 down 0.0684 RRSL_04592 2-hydroxychromene-2-carboxylate isomerase( EC:5.3.99.- )638718742 9.258779869 8.853022449 1.461 up 0.152 RRSL_04593 Hypothetical Protein638718753 9.860254869 8.835522449 2.244 up 0.0561 RRSL_04604 Hypothetical Protein638718775 9.827079869 10.05737245 1.063 down 0.691 RRSL_04627 Serine racemase( EC:5.1.1.- )638718786 9.861979869 9.505597449 1.412 up 0.184 RRSL_04637 Hypothetical Protein638718795 13.85590487 14.71189745 1.64 down 0.0245 RRSL_04647 Hypothetical Protein638718796 11.35152987 12.26459745 1.706 down 0.108 RRSL_04648 Superfamily I DNA helicase638718800 7.868329869 7.616072449 1.313 up 0.2 RRSL_04652 Hypothetical Protein638718801 8.014879869 8.015247449 1.102 up 0.192 RRSL_04653 Hypothetical Protein638718802 16.31730487 16.44294745 1.011 up 0.897 RRSL_04654 Hypothetical Protein638718803 9.967854869 9.628847449 1.395 up 0.133 RRSL_04656 Hypothetical Protein638718807 9.603979869 9.060797449 1.607 up 0.0433 RRSL_04659 Hypothetical Protein638718817 7.418929869 7.930647449 1.292 down 0.224 RRSL_04669 Hypothetical Protein638718841 12.58207987 13.60417245 1.84 down 0.0232 RRSL_04695 Hypothetical Protein638718842 14.12757987 14.38902245 1.086 down 0.474 RRSL_04696 Hypothetical Protein638718843 13.77697987 14.22747245 1.238 down 0.188 RRSL_04697 Hypothetical Protein638718844 14.75232987 15.16667245 1.208 down 0.0397 RRSL_04698 Hypothetical Protein638718845 13.40847987 14.16597245 1.532 down 0.0211 RRSL_04699 Hypothetical Protein638718848 13.32517987 14.24197245 1.711 down 0.0253 RRSL_04702 Hypothetical Protein638718849 13.29117987 14.35867245 1.899 down 0.0071 RRSL_04703 Hypothetical Protein638718869 7.266479869 7.681547449 1.208 down 0.367 RRSL_04726 Hypothetical Protein638718880 6.763879869 6.994422449 1.063 down 0.761 RRSL_04737 Hypothetical Protein638718881 8.304879869 7.924222449 1.436 up 0.117 RRSL_04738 Arginine exporter638718894 11.06392987 10.88732245 1.246 up 0.288 RRSL_04752 Hypothetical Protein638718943 9.090129869 9.557222449 1.253 down 0.0265 RRSL_04398 Endonuclease III( EC:4.2.99.18 )638718960 12.41097987 12.99564745 1.359 down 0.0216 RRSL_04416 Aminotransferase class I family

638718964 9.851079869 9.231922449 1.694 up 0.243 RRSL_04420 Serine protease( EC:3.4.21.- )638718977 9.449179869 9.369797449 1.165 up 0.096 RRSL_04433 hypothetical protein638718978 11.78355487 12.85009745 1.898 down 0.0911 RRSL_RNA039 ( tRNA )638718988 12.83815487 11.98632245 1.991 up 0.00565 RRSL_04446 hypothetical protein638718989 12.53847987 11.77867245 1.868 up 0.0181 RRSL_04447 hypothetical protein638719023 9.461229869 10.29527245 1.615 down 0.0421 RRSL_04482 Predicted O-linked N-acetylglucosamine transferase638719026 10.78877987 10.38314745 1.461 up 0.184 RRSL_04486 hypothetical protein638719041 7.958129869 8.044797449 1.038 up 0.767 RRSL_04502 transposase COG4584638719042 12.08380487 11.76394745 1.377 up 0.11 RRSL_04503 putative transposase638719043 11.98177987 11.84857245 1.209 up 0.138 RRSL_04504 Putative transposase638719044 10.35097987 10.58604745 1.066 down 0.778 RRSL_04505 hypothetical protein638719045 11.01247987 10.27079745 1.844 up 0.00877 RRSL_04506 hypothetical protein638719046 9.434454869 10.08904745 1.426 down 0.00917 RRSL_04507 hypothetical protein638719047 9.424279869 9.013072449 1.467 up 0.202 RRSL_04508 hypothetical protein638719048 9.246504869 9.117322449 1.206 up 0.074 RRSL_04509 Transcriptional regulator, AraC family638719049 8.712304869 8.531297449 1.25 up 0.183 RRSL_04510 4-carboxymuconolactone decarboxylase638719071 12.34407987 12.41777245 1.048 up 0.74 RRSL_04532 Transporter, drug/metabolite exporter family638719082 14.31267987 14.75612245 1.232 down 0.254 RRSL_RNA043 ( tRNA )638719103 10.88657987 11.51324745 1.399 down 0.00869 RRSL_04564 hypothetical protein638719119 9.813104869 8.680497449 2.418 up 0.111 RRSL_04581 hypothetical protein638719127 14.11722987 15.35167245 2.132 down 0.0515 RRSL_RNA041 ( tRNA )638719130 8.971779869 9.214347449 1.072 down 0.625 RRSL_04277 Hypothetical Protein638719132 16.15812987 16.30512245 1.003 down 0.975 RRSL_04279 Hypothetical Protein638719133 16.58060487 16.82062245 1.07 down 0.218 RRSL_04280 Hypothetical Protein638719142 13.39300487 13.08442245 1.366 up 0.00114 RRSL_04290 Hypothetical Protein638719143 10.47905487 10.70612245 1.06 down 0.798 RRSL_04292 Hypothetical Protein638719144 13.42310487 13.93667245 1.294 down 0.0424 RRSL_04294 probable transcription regulator protein638719185 9.679929869 9.322797449 1.413 up 0.0646 RRSL_04337 Hypothetical Protein638719190 8.422779869 7.554397449 2.014 up 0.189 RRSL_04343 RNA polymerase sigma factor SigJ638719196 7.600229869 8.566247449 1.77 down 0.0256 RRSL_04349 Hypothetical Protein638719219 9.079154869 9.167072449 1.037 up 0.845 RRSL_04375 Phosphohydrolase (MutT/nudix family protein)638719223 8.753104869 7.761072449 2.194 up 0.0966 RRSL_04379 Hypothetical Protein638719233 7.953129869 8.558972449 1.379 down 0.172 RRSL_04047 Core protein638719234 8.192254869 7.585872449 1.679 up 0.0552 RRSL_04048 Transposase638719235 8.439154869 8.434022449 1.107 up 0.732 RRSL_04049 Transposase638719236 13.43405487 13.01697245 1.473 up 0.000912 RRSL_04050 Hypothetical Protein638719238 11.06087987 10.25482245 1.928 up 0.0361 RRSL_04053 Hypothetical Protein638719240 16.35180487 16.60867245 1.083 down 0.383 RRSL_04058 Hypothetical Protein638719241 16.18592987 16.21347245 1.082 up 0.614 RRSL_04059 Hypothetical Protein638719242 14.23195487 14.24777245 1.091 up 0.499 RRSL_04060 Hypothetical Protein638719243 12.01405487 12.94372245 1.726 down 0.0107 RRSL_04061 Hypothetical Protein638719245 11.36980487 12.01722245 1.419 down 0.00517 RRSL_04063 Short chain dehydrogenase638719246 8.507279869 9.343347449 1.618 down 0.00472 RRSL_04064 Hypothetical Protein638719247 9.224104869 8.591397449 1.71 up 0.105 RRSL_04065 Hypothetical Protein638719260 13.26332987 14.34552245 1.919 down 0.0216 RRSL_04079 Hypothetical Protein638719268 8.212854869 8.684322449 1.256 down 0.238 RRSL_04088 Salicylate hydroxylase( EC:1.14.13.1 )638719271 8.296629869 8.665622449 1.17 down 0.288 RRSL_04090 PhnM protein638719272 9.203004869 9.223697449 1.087 up 0.518 RRSL_04091 Hypothetical Protein638719321 8.766179869 8.258997449 1.567 up 0.0852 RRSL_04142 MaoC-like protein638719322 8.587379869 8.686122449 1.03 up 0.845 RRSL_04144 3-ketoacyl-CoA thiolase( EC:2.3.1.16 )638719323 10.61655487 9.443022449 2.488 up 0.125 RRSL_04146 Long-chain-fatty-acid--CoA ligase( EC:6.2.1.3 )638719324 14.73940487 13.74084745 2.204 up 0.101 RRSL_04147 Outer membrane protein638719330 7.866429869 7.892247449 1.083 up 0.845 RRSL_04153 Hypothetical Protein638719339 6.602079869 6.880572449 1.099 down 0.57 RRSL_04163 Zinc metalloprotease( EC:3.4.24.- )638719342 9.422829869 9.581147449 1.011 down 0.931 RRSL_04167 Isochorismatase( EC:3.3.2.1 )638719347 8.928204869 8.564922449 1.419 up 0.00877 RRSL_04172 Hypothetical Protein638719355 9.521554869 8.738947449 1.897 up 0.0399 RRSL_04181 Hypothetical Protein

638719368 7.998279869 8.337297449 1.146 down 0.388 RRSL_04194 Hypothetical Protein638719371 11.42660487 11.64209745 1.052 down 0.843 RRSL_04197 Hypothetical Protein638719372 11.61820487 11.74902245 1.007 up 0.958 RRSL_04198 Hypothetical Protein638719408 9.918629869 10.08174745 1.014 down 0.922 RRSL_04235 Succinate-semialdehyde dehydrogenase (NADP+)( EC:1.2.1.16 )638719418 10.55165487 8.642722449 4.142 up 0.108 RRSL_04244 nhaC NhaC638719434 9.862029869 11.34754745 2.538 down 0.0661 RRSL_04260 Hypothetical Protein638719443 8.738779869 8.693072449 1.138 up 0.326 RRSL_04268 Deoxyribodipyrimidine photolyase( EC:4.1.99.3 )638719452 13.39410487 14.46414745 1.903 down 0.0734 RRSL_RNA034 ( tRNA )638719454 9.709304869 9.533422449 1.246 up 0.433 RRSL_03829 Hypothetical Protein638719473 9.840929869 10.27527245 1.224 down 0.325 RRSL_03850 Hypothetical Protein638719474 8.871279869 9.217772449 1.152 down 0.502 RRSL_03852 Core protein638719477 8.996504869 9.409522449 1.206 down 0.208 RRSL_03855 Hypothetical Protein638719482 6.704254869 7.445897449 1.515 down 0.0224 RRSL_03860 Hypothetical Protein638719509 14.65067987 14.37082245 1.339 up 0.115 RRSL_RNA035 ( tRNA )638719538 10.35025487 10.41427245 1.055 up 0.793 RRSL_03919 Transcriptional regulators, LysR family638719543 8.707429869 8.764922449 1.06 up 0.855 RRSL_03924 Transcriptional regulators, LysR family638719544 8.836279869 8.895647449 1.058 up 0.738 RRSL_03925 Hypothetical Protein638719552 9.383354869 9.630572449 1.075 down 0.734 RRSL_03933 (partial?) integrase638719553 10.67210487 10.95497245 1.102 down 0.615 RRSL_03934 Hypothetical Protein638719554 10.44687987 10.53764745 1.035 up 0.88 RRSL_03935 Hypothetical Protein638719557 8.074404869 7.560897449 1.574 up 0.325 RRSL_03938 RTX family calcium-binding cytotoxins and bacteriocins638719558 15.94240487 16.21569745 1.095 down 0.554 RRSL_03939 hypothetical protein638719559 9.794279869 10.43769745 1.415 down 0.0433 RRSL_03940 hypothetical protein638719560 10.87507987 11.71734745 1.625 down 0.00312 RRSL_03941 hypothetical protein638719563 9.847279869 9.649847449 1.264 up 0.202 RRSL_03944 Transcriptional regulator, MarR family638719575 11.49462987 10.96667245 1.59 up 0.0369 RRSL_03956 hypothetical protein638719603 11.08190487 10.93159745 1.224 up 0.0646 RRSL_03985 hypothetical protein638719607 10.61070487 10.94397245 1.142 down 0.0159 RRSL_03989 putative MFS transporter638719627 9.091379869 8.701847449 1.445 up 0.121 RRSL_04009 hypothetical protein638719630 9.454454869 9.168922449 1.344 up 0.197 RRSL_04013 RHS-related protein638719631 10.54670487 10.06824745 1.537 up 0.0633 RRSL_04014 RHS-related protein638719642 10.73562987 10.11587245 1.695 up 0.112 RRSL_04025 hypothetical protein638719646 9.297604869 10.56837245 2.187 down 0.0708 RRSL_04029 VGR-related protein638719649 9.876929869 10.10804745 1.063 down 0.798 RRSL_04032 hypothetical protein638719689 10.51640487 11.08997245 1.348 down 0.0796 RRSL_03472 Hypothetical Protein638719719 12.94455487 13.58884745 1.416 down 0.152 RRSL_03502 rpoD RpoD638719720 14.29165487 14.54907245 1.083 down 0.382 RRSL_03503 RNA polymerase sigma factor rpoD638719726 13.73412987 14.08332245 1.154 down 0.265 RRSL_03508 Hypothetical Protein638719744 11.05812987 11.75937245 1.473 down 0.18 RRSL_03529 Hypothetical Protein638719795 8.951679869 9.124197449 1.021 down 0.871 RRSL_03756 hypothetical protein638719804 14.17375487 13.20329745 2.161 up 0.103 RRSL_03766 hypothetical protein638719829 10.61917987 10.51704745 1.184 up 0.226 RRSL_03794 ubiB UbiB638719830 8.813629869 8.994222449 1.027 down 0.904 RRSL_03795 hypothetical protein638719859 8.111804869 8.228772449 1.017 up 0.938 RRSL_03557 Hypothetical Protein638719863 7.499354869 7.696472449 1.039 down 0.76 RRSL_03561 Hypothetical Protein638719864 7.457129869 7.512947449 1.061 up 0.827 RRSL_03562 Hypothetical Protein638719865 9.718579869 8.495872449 2.574 up 0.118 RRSL_03563 Hypothetical Protein638719873 9.738104869 9.481072449 1.318 up 0.117 RRSL_03571 Peptidyl-prolyl cis-trans isomerase( EC:5.2.1.8 )638719947 11.65835487 10.94319745 1.811 up 0.195 RRSL_03649 Transcriptional regulators, LysR family638719948 8.715729869 8.305572449 1.465 up 0.203 RRSL_03648 Hypothetical Protein638719949 15.72372987 16.01287245 1.107 down 0.433 RRSL_00715 Protein translocase subunit YajC638719982 9.172279869 9.599772449 1.219 down 0.103 RRSL_02698 Hypothetical Protein638720050 10.03115487 10.73007245 1.471 down 0.0267 RRSL_03279 fumarylpyruvate hydrolase( EC:3.7.1.5 )638720100 7.699754869 7.913872449 1.051 down 0.826 RRSL_03330 Transposase638720111 12.44282987 12.07572245 1.422 up 0.00661 RRSL_03341 Hypothetical Protein638720113 10.18812987 9.983722449 1.271 up 0.433 RRSL_03343 Hypothetical Protein638720114 9.500154869 8.722722449 1.89 up 0.0966 RRSL_03344 Hypothetical Protein

638720115 9.459754869 8.510672449 2.129 up 0.0703 RRSL_03345 Hypothetical Protein638720116 7.182004869 6.836047449 1.402 up 0.16 RRSL_03346 Hypothetical Protein638720117 10.27617987 10.29157245 1.091 up 0.532 RRSL_03347 Hypothetical Protein638720118 8.122804869 8.036922449 1.17 up 0.557 RRSL_03348 Hypothetical Protein638720119 8.373879869 7.526597449 1.984 up 0.136 RRSL_03349 Hypothetical Protein638720120 9.108029869 9.334022449 1.06 down 0.792 RRSL_03350 Hypothetical Protein638720121 9.598654869 9.868472449 1.092 down 0.631 RRSL_03351 Hypothetical Protein638720122 10.92992987 10.93694745 1.097 up 0.351 RRSL_03352 Rep protein638720123 12.85962987 12.20374745 1.738 up 0.00252 RRSL_03353 Hypothetical Protein638720127 14.64650487 14.98747245 1.148 down 0.133 RRSL_03357 Hypothetical Protein638720128 12.38625487 12.90767245 1.301 down 0.0109 RRSL_03359 DNA modification methyltransferase-related protein638720129 10.68167987 11.64604745 1.768 down 0.0168 RRSL_03360 Hypothetical cytosolic protein638720130 12.05455487 12.25359745 1.04 down 0.735 RRSL_03361 Hypothetical cytosolic protein638720131 10.70570487 10.62112245 1.169 up 0.495 RRSL_03362 Hypothetical Protein638720135 10.04825487 11.03314745 1.794 down 0.00537 RRSL_03655 Hypothetical Protein638720136 10.93855487 11.38452245 1.234 down 0.358 RRSL_03656 Hypothetical protein638720137 12.37650487 12.20667245 1.241 up 0.222 RRSL_03657 Hypothetical Protein638720149 11.66145487 11.51647245 1.219 up 0.246 RRSL_03670 Hypothetical Protein638720177 9.333829869 9.604472449 1.093 down 0.754 RRSL_03698 Hypothetical Protein638720179 12.11752987 11.69554745 1.478 up 0.0757 RRSL_03700 Hypothetical Protein638720180 13.36337987 13.07909745 1.343 up 0.00285 RRSL_03702 Hypothetical Protein638720191 8.091254869 7.560322449 1.593 up 0.0394 RRSL_03713 Feruloyl-CoA synthetase638720197 9.460229869 8.762622449 1.789 up 0.0133 RRSL_03720 SAM-dependent methyltransferase638720201 7.054654869 7.982447449 1.724 down 0.00764 RRSL_03724 Hypothetical Protein638720221 6.991204869 7.437122449 1.234 down 0.0527 RRSL_03385 Transposase638720222 7.125329869 7.899022449 1.549 down 0.0271 RRSL_03386 Hypothetical Protein638720224 8.291579869 9.367047449 1.91 down 0.032 RRSL_03388 Serine/threonine protein phosphatase( EC:3.1.3.16 )638720226 12.42980487 12.82544745 1.192 down 0.284 RRSL_03390 DNA-damage-inducible protein J638720227 12.07777987 12.14342245 1.054 up 0.651 RRSL_03391 yafQ YafQ638720228 9.291704869 9.537397449 1.074 down 0.639 RRSL_03392 virulence gene repressor RsaL638720229 11.08877987 10.56837245 1.582 up 0.134 RRSL_03393 Hypothetical Protein638720246 11.85747987 11.18474745 1.758 up 0.0274 RRSL_03411 Hypothetical protein638720247 8.463129869 7.798847449 1.748 up 0.00191 RRSL_03412 Hypothetical Protein638720248 7.680029869 7.971347449 1.109 down 0.257 RRSL_03413 Hypothetical Protein638720249 8.373754869 7.962297449 1.467 up 0.0239 RRSL_03414 Hypothetical Protein638720254 7.997129869 7.723347449 1.333 up 0.179 RRSL_03419 Transcriptional regulators, LysR family638720255 10.72517987 10.13752245 1.657 up 0.226 RRSL_03420 Hypothetical Protein638720273 11.76867987 11.43352245 1.391 up 0.0742 RRSL_03011 Hypothetical Protein638720275 7.538704869 7.290347449 1.31 up 0.183 RRSL_03015 Poly(3-hydroxyalkanoate) polymerase( EC:2.3.1.- )638720276 8.643229869 7.796722449 1.983 up 0.104 RRSL_03016 Poly(3-hydroxyalkanoate) polymerase( EC:2.3.1.- )638720303 11.96745487 11.14532245 1.95 up 0.138 RRSL_03048 Hypothetical Protein638720304 9.517904869 8.705697449 1.937 up 0.216 RRSL_03049 Oxidoreductase( EC:1.1.1.- )638720305 9.549704869 8.146147449 2.918 up 0.103 RRSL_03050 Transcriptional regulators, LysR family638720306 7.734054869 7.758197449 1.084 up 0.467 RRSL_03051 Hypothetical Protein638720307 7.876254869 8.017697449 1 RRSL_03052 Hypothetical Protein638720308 7.450029869 7.901822449 1.239 down 0.288 RRSL_03053 Transposase638720309 10.73355487 9.093797449 3.437 up 0.0774 RRSL_03054 Hypothetical Protein638720310 10.15715487 10.46304745 1.12 down 0.523 RRSL_03055 Bacitracin resistance protein (Putative undecaprenol kinase)( EC:2.7.1.66 )638720323 8.479854869 9.195972449 1.489 down 0.00276 RRSL_03069 Transcriptional regulator, AraC family638720324 8.857279869 9.031897449 1.023 down 0.904 RRSL_03070 Hypothetical Protein638720331 8.221854869 8.432197449 1.048 down 0.845 RRSL_03078 Hypothetical Protein638720334 10.67977987 11.58477245 1.697 down 0.0388 RRSL_03082 Hypothetical Protein638720346 10.67570487 10.66524745 1.111 up 0.806 RRSL_03096 Hypothetical Protein638720354 12.09655487 11.77254745 1.38 up 0.0143 RRSL_02932 Hypothetical Protein638720356 8.919729869 8.812397449 1.188 up 0.426 RRSL_02935 Hypothetical Protein638720357 10.15817987 9.301722449 1.997 up 0.0141 RRSL_02937 Hypothetical Protein638720358 7.638954869 8.478047449 1.621 down 0.0155 RRSL_02938 Hypothetical Protein

638720372 9.835204869 9.431922449 1.458 up 0.0139 RRSL_02952 Two-component response regulator638720395 9.533054869 10.67204745 1.996 down 0.0209 RRSL_02976 Hypothetical Protein638720397 11.25867987 11.83742245 1.353 down 0.255 RRSL_02978 Hypothetical Protein638720399 8.180604869 7.923672449 1.318 up 0.33 RRSL_02980 Hypothetical Protein638720401 11.79440487 11.52117245 1.333 up 0.35 RRSL_02983 Hypothetical Protein638720402 10.15435487 9.835147449 1.376 up 0.224 RRSL_02982 FMN-dependent NADH-azoreductase( EC:1.6.99.2 )638720403 10.06667987 10.16892245 1.027 up 0.841 RRSL_02984 Transcriptional regulator, TetR family638720404 7.719604869 8.045097449 1.135 down 0.581 RRSL_02985 Thiosulfate sulfurtransferase( EC:2.8.1.1 )638720405 7.048704869 7.669747449 1.394 down 0.143 RRSL_02986 Cystathionine beta-lyase( EC:4.4.1.8 )638720420 6.687279869 6.900472449 1.05 down 0.489 RRSL_03003 Hypothetical Protein638720421 8.865229869 8.217497449 1.728 up 0.137 RRSL_03004 Amino acid ABC transporter permease protein638720422 7.755654869 7.816572449 1.057 up 0.817 RRSL_03006 Hypothetical Protein638720423 11.86830487 9.267272449 6.693 up 0.0612 RRSL_03008 Hypothetical Protein638720485 7.858479869 7.751822449 1.187 up 0.708 RRSL_03251 Hypothetical Protein638720487 9.202004869 9.415847449 1.051 down 0.829 RRSL_03253 Hypothetical Protein638720488 9.440079869 9.258222449 1.251 up 0.231 RRSL_03254 Hypothetical Protein638720489 7.480029869 7.661947449 1.028 down 0.857 RRSL_03255 N-carbamoyl-L-amino acid amidohydrolase( EC:3.5.1.- )638720490 9.663254869 9.175947449 1.546 up 0.275 RRSL_03256 Putative diaminopropionate ammonia-lyase( EC:4.3.1.15 )638720497 14.69382987 15.57102245 1.664 down 0.00416 RRSL_03265 Protein translocase subunit YajC638720498 7.894054869 7.174072449 1.817 up 0.138 RRSL_02236 Peptide synthetase638720499 11.23620487 10.29674745 2.115 up 0.0914 RRSL_02238 Phage protein638720500 11.79987987 10.07517245 3.646 up 0.0596 RRSL_02239 Hypothetical Protein638720509 8.328579869 7.874622449 1.511 up 0.061 RRSL_02248 Acetyl-coenzyme A synthetase( EC:6.2.1.1 )638720511 8.121179869 8.079147449 1.135 up 0.281 RRSL_02250 NAD-specific glutamate dehydrogenase( EC:1.4.1.2 )638720512 11.14717987 10.85177245 1.353 up 0.183 RRSL_02251 Hypothetical Protein638720513 10.11742987 10.71442245 1.371 down 0.0732 RRSL_02252 Hypothetical Protein638720520 12.03000487 11.57007245 1.517 up 0.175 RRSL_02259 Hypothetical Protein638720561 8.006954869 8.080097449 1.048 up 0.764 RRSL_02875 Transcriptional regulators, LysR family638720564 8.670279869 9.117897449 1.236 down 0.0944 RRSL_02878 hypothetical protein638720568 9.247454869 10.04772245 1.578 down 0.0512 RRSL_02883 hypothetical protein638720570 8.913104869 9.622497449 1.482 down 0.0879 RRSL_02885 hypothetical protein638720572 11.83400487 11.93882245 1.025 up 0.871 RRSL_02887 hypothetical protein638720574 10.96015487 11.60604745 1.418 down 0.0512 RRSL_02889 hypothetical protein638720575 11.54627987 12.49209745 1.746 down 0.162 RRSL_RNA028 ( tRNA )638720581 9.562329869 8.884672449 1.764 up 0.144 RRSL_02895 hypothetical protein638720582 8.088079869 8.433947449 1.152 down 0.562 RRSL_02896 Lipase( EC:3.1.1.3 )638720583 9.736904869 9.162047449 1.643 up 0.268 RRSL_02897 Short chain dehydrogenase638720584 9.877329869 9.131797449 1.849 up 0.286 RRSL_02898 Cyclohexanone monooxygenase( EC:1.14.13.22 )638720588 8.745704869 8.249372449 1.556 up 0.143 RRSL_02902 hypothetical protein638720596 10.32370487 12.03592245 2.97 down 0.203 RRSL_02911 hypothetical protein638720632 8.603129869 8.637547449 1.077 up 0.332 RRSL_02808 Ureidoglycolate hydrolase( EC:3.5.3.19 )638720652 11.39475487 10.65144745 1.846 up 0.245 RRSL_RNA027 ( tRNA )638720655 9.419754869 9.216347449 1.27 up 0.401 RRSL_02834 Hypothetical Protein638720660 8.120079869 8.440497449 1.131 down 0.708 RRSL_02839 livF LivF638720661 9.502029869 7.717622449 3.8 up 0.0717 RRSL_02841 livM LivM638720712 11.16277987 11.34379745 1.027 down 0.761 RRSL_02745 Signal peptide protein638720726 12.46787987 12.94504745 1.261 down 0.239 RRSL_RNA026 ( tRNA )638720750 12.41300487 12.62612245 1.05 down 0.641 RRSL_02782 Amidotransferase hisH( EC:2.4.2.- )638720752 10.99670487 11.68017245 1.455 down 0.00325 RRSL_02784 Histidinol-phosphate aminotransferase( EC:2.6.1.9 )638720753 12.37855487 12.85039745 1.257 down 0.422 RRSL_02043 Core protein638720754 10.57762987 10.62639745 1.066 up 0.654 RRSL_02044 Hypothetical Protein638720766 9.812604869 10.96469745 2.014 down 0.0817 RRSL_02056 Hypothetical Protein638720769 10.10280487 9.957847449 1.219 up 0.436 RRSL_02059 Hypothetical Protein638720770 7.906254869 8.537847449 1.404 down 0.2 RRSL_02060 drug/metabolite transporter (DMT) permease638720771 9.870529869 10.86219745 1.802 down 0.0571 RRSL_02061 Transcriptional regulators, LysR family638720773 9.299479869 9.486147449 1.031 down 0.912 RRSL_02064 Hypothetical Protein638720775 11.08745487 10.50117245 1.656 up 0.236 RRSL_02066 Hypothetical Protein

638720778 11.42600487 11.50554745 1.044 up 0.858 RRSL_02070 Hypothetical Protein638720779 11.52442987 11.44954745 1.161 up 0.374 RRSL_02071 Deoxyuridylate hydroxymethyltransferase( EC:2.1.2.- )638720781 7.908104869 7.823147449 1.17 up 0.357 RRSL_02074 probable hemagglutinin-related signal peptide protein638720782 7.766154869 7.751072449 1.114 up 0.44 RRSL_02075 Hemolysin activator protein precursor638720784 7.818804869 7.705797449 1.193 up 0.348 RRSL_02077 Hypothetical Protein638720785 10.34847987 10.22149745 1.204 up 0.199 RRSL_02078 hypothetical638720786 10.28290487 10.08689745 1.263 up 0.219 RRSL_02079 transposase remnant638720787 8.483004869 8.940672449 1.244 down 0.2 RRSL_02080 Cyclopropane-fatty-acyl-phospholipid synthase( EC:2.1.1.79 )638720788 7.344054869 7.391972449 1.067 up 0.77 RRSL_02081 Hypothetical Protein638720792 9.039254869 8.966422449 1.16 up 0.425 RRSL_02085 FldX protein638720793 7.506504869 7.664422449 1.011 down 0.921 RRSL_02086 Outer membrane porin protein 32 precursor638720794 6.996629869 7.212297449 1.052 down 0.54 RRSL_02087 4-carboxy-4-hydroxy-2-oxoadipate aldolase( EC:4.1.3.17 )638720795 7.937279869 7.724397449 1.278 up 0.308 RRSL_02088 4-oxalomesaconate hydratase( EC:4.2.1.- )638720796 7.880604869 8.139822449 1.084 down 0.712 RRSL_02089 Transcriptional regulators, LysR family638720797 9.573904869 9.258572449 1.372 up 0.107 RRSL_02091 4-hydroxybenzoate transporter638720798 9.321104869 9.491672449 1.02 down 0.869 RRSL_02092 Hypothetical protein638720811 11.25675487 10.72394745 1.596 up 0.0229 RRSL_02291 Hypothetical Protein638720818 9.560204869 9.037447449 1.584 up 0.0142 RRSL_02299 Hypothetical Protein638720820 7.427754869 6.964097449 1.521 up 0.0431 RRSL_02301 Hypothetical Protein638720824 8.575704869 8.672722449 1.031 up 0.878 RRSL_02305 Hypothetical Protein638720825 9.582529869 8.348372449 2.595 up 0.115 RRSL_02306 Hypothetical Protein638720870 11.37410487 11.47809745 1.026 up 0.936 RRSL_02353 Hypothetical Protein638720872 13.41845487 12.57014745 1.986 up 0.0221 RRSL_02355 Bacterial Protein Translation Initiation Factor 1 (IF-1)638720878 7.531129869 7.711072449 1.026 down 0.86 RRSL_02363 2-hydroxymuconic semialdehyde hydrolase( EC:3.7.1.9 )638720888 11.15015487 10.56789745 1.651 up 0.202 RRSL_02376 Zinc metalloprotease( EC:3.4.24.- )638720890 12.66410487 12.36902245 1.353 up 0.341 RRSL_02378 Hypothetical Protein638720906 7.931104869 7.820672449 1.19 up 0.303 RRSL_02394 Universal stress protein family638720911 8.299054869 9.123222449 1.604 down 0.0225 RRSL_02399 Shikimate kinase( EC:2.7.1.71 )638720912 7.913279869 7.777272449 1.212 up 0.291 RRSL_02400 Hypothetical Protein638720913 7.625179869 7.744647449 1.015 up 0.929 RRSL_02401 Hypothetical Protein638720914 7.574729869 8.104372449 1.308 down 0.154 RRSL_02402 Mu-like prophage FluMu protein gp29638720915 8.900829869 9.134322449 1.065 down 0.773 RRSL_02403 Phage protein638720916 7.124129869 7.292622449 1.018 down 0.869 RRSL_02404 Hypothetical Protein638720917 6.650354869 7.737472449 1.925 down 0.0499 RRSL_02405 Hypothetical Protein638720918 10.30755487 10.41549745 1.023 up 0.939 RRSL_02406 Hypothetical Protein638720919 8.074279869 8.378022449 1.118 down 0.67 RRSL_02408 Phage protein638720920 13.64937987 14.06517245 1.209 down 0.0748 RRSL_02409 Hypothetical Protein638720921 9.272804869 9.935372449 1.434 down 0.18 RRSL_02410 conserved hypothetical protein638720922 7.262404869 7.477997449 1.052 down 0.777 RRSL_02411 hypothetical protein638720923 8.426679869 8.756822449 1.139 down 0.549 RRSL_02412 Transposase638720924 7.645754869 8.464222449 1.598 down 0.0823 RRSL_02413 DNA transposition protein638720925 9.103679869 9.629397449 1.304 down 0.451 RRSL_02415 Hypothetical Protein638720926 8.894379869 9.419547449 1.304 down 0.0573 RRSL_02414 Conserved hypothetical protein638720927 9.162129869 9.684997449 1.302 down 0.0715 RRSL_02416 Conserved hypothetical protein638720929 7.319804869 7.561822449 1.072 down 0.7 RRSL_02418 Conserved hypothetical protein638720932 7.698504869 8.276872449 1.353 down 0.164 RRSL_02422 Possible Mu-like prophage FluMu I protein638720933 7.409104869 7.941772449 1.311 down 0.0207 RRSL_02423 Possible Mu-like prophage FluMu major head subunit638720934 9.480154869 9.951047449 1.256 down 0.243 RRSL_02424 Hypothetical protein638720935 7.014304869 7.640722449 1.399 down 0.0258 RRSL_02425 Conserved hypothetical protein638720936 7.566079869 8.217347449 1.423 down 0.201 RRSL_02426 Hypothetical Protein638720937 8.456304869 9.194497449 1.512 down 0.0214 RRSL_02427 gpl Gpl638720938 7.182579869 7.646547449 1.25 down 0.234 RRSL_02428 Conserved hypothetical protein638720939 7.315779869 7.837322449 1.301 down 0.0297 RRSL_02429 probable gene 66 protein638720940 6.705754869 7.613397449 1.7 down 0.0428 RRSL_02430 Hypothetical protein638720941 9.006554869 8.524947449 1.54 up 0.298 RRSL_02431 Conserved hypothetical protein638720942 7.649079869 7.856647449 1.046 down 0.855 RRSL_02432 Putative phage FluMu DNA circulation protein638720943 8.389704869 8.157447449 1.295 up 0.252 RRSL_02433 putative bacteriophage tail protein (gpP)

638720944 12.23835487 11.99814745 1.303 up 0.147 RRSL_02434 phage baseplate assembly protein V subfamily638720945 7.588504869 8.220272449 1.404 down 0.0392 RRSL_02435 Hypothetical Protein638720946 8.024104869 8.828122449 1.582 down 0.0538 RRSL_02436 Putative bacteriophage protein638720947 11.00552987 11.24592245 1.07 down 0.586 RRSL_02437 Hypothetical protein638720948 7.644254869 8.436497449 1.569 down 0.105 RRSL_02438 Hypothetical protein638720950 10.23360487 10.09937245 1.21 up 0.0731 RRSL_02440 Hypothetical Protein638720951 10.06645487 10.43939745 1.173 down 0.421 RRSL_RNA022 ( tRNA )638720987 7.108079869 7.513447449 1.2 down 0.298 RRSL_02206 Hypothetical Protein638720988 7.317179869 7.313522449 1.105 up 0.817 RRSL_02207 Hypothetical Protein638720989 9.080404869 8.888197449 1.26 up 0.245 RRSL_02209 Hypothetical Protein638720990 10.32510487 11.26489745 1.738 down 0.173 RRSL_02208 Hypothetical Protein638720992 10.52660487 11.16779745 1.413 down 0.0978 RRSL_02211 Hypothetical Protein638720998 8.849754869 8.543597449 1.364 up 0.184 RRSL_02218 Hypothetical Protein638721001 7.195304869 7.009597449 1.254 up 0.0575 RRSL_02221 Hypothetical Protein638721019 8.397504869 7.881247449 1.577 up 0.0996 RRSL_03125 NAD(P) transhydrogenase subunit beta( EC:1.6.1.2 )638721021 11.02095487 11.75922245 1.512 down 0.0878 RRSL_03122 Hypothetical Protein638721022 10.21077987 11.57204745 2.328 down 0.0653 RRSL_03121 Hypothetical Protein638721023 8.942554869 8.555672449 1.442 up 0.0804 RRSL_03120 Hypothetical Protein638721024 10.50347987 10.08294745 1.476 up 0.0242 RRSL_03119 Hypothetical Protein638721030 8.301229869 9.316447449 1.832 down 0.0111 RRSL_03112 ftsK FtsK638721031 12.35452987 12.21874745 1.212 up 0.57 RRSL_03111 Hypothetical Protein638721040 10.35787987 9.547647449 1.934 up 0.0232 RRSL_03101 Lactoylglutathione lyase638721041 7.765929869 7.619722449 1.22 up 0.228 RRSL_03100 transcriptional regulator, LysR family638721043 8.288379869 8.384397449 1.032 up 0.799 RRSL_02447 conserved hypothetical protein638721044 9.262054869 9.900672449 1.411 down 0.161 RRSL_02445 Conserved hypothetical protein638721045 8.767479869 8.527447449 1.302 up 0.318 RRSL_02444 Hypothetical Protein638721074 8.145679869 8.140447449 1.107 up 0.604 RRSL_00500 Hypothetical Protein638721106 11.28815487 10.69654745 1.662 up 0.161 RRSL_03165 Hypothetical Protein638721107 9.270204869 8.508747449 1.87 up 0.089 RRSL_03166 JemB638721127 16.23860487 16.30302245 1.055 up 0.628 RRSL_03187 Transposase638721169 9.588404869 9.309272449 1.338 up 0.405 RRSL_02149 Hypothetical protein638721171 10.45472987 10.03487245 1.475 up 0.313 RRSL_02151 Hypothetical Protein638721174 10.80755487 10.68924745 1.197 up 0.39 RRSL_02154 Hypothetical protein638721175 12.38700487 12.21224745 1.245 up 0.0835 RRSL_02155 Hypothetical cytosolic protein638721176 8.259754869 7.576297449 1.771 up 0.00214 RRSL_02156 Rieske-type ferredoxin638721177 10.36985487 9.883197449 1.545 up 0.0295 RRSL_02157 Hypothetical protein638721178 7.989029869 7.737497449 1.313 up 0.242 RRSL_02158 Hypothetical protein638721187 9.135654869 8.614547449 1.583 up 0.237 RRSL_02167 Hypothetical protein638721191 10.30130487 9.537047449 1.873 up 0.0242 RRSL_02515 hypothetical protein638721192 9.672654869 7.156122449 6.312 up 0.0612 RRSL_02517 hypothetical protein638721217 8.420954869 8.193922449 1.291 up 0.0689 RRSL_02546 hypothetical protein638721219 7.507979869 8.135272449 1.4 down 0.0404 RRSL_02548 ferric siderophore receptor638721221 12.28072987 11.67417245 1.679 up 0.0177 RRSL_02550 hypothetical protein638721230 10.78257987 11.10954745 1.137 down 0.659 RRSL_02560 Conserved hypothetical protein638721232 9.467279869 9.307497449 1.232 up 0.396 RRSL_02562 chrA ChrA638721237 8.447529869 8.002197449 1.502 up 0.242 RRSL_02567 hypothetical protein638721251 15.38722987 14.71444745 1.758 up 0.0121 RRSL_02457 Hypothetical Protein638721253 12.60715487 12.60754745 1.102 up 0.71 RRSL_02459 Hypothetical Protein638721259 7.511679869 8.041722449 1.308 down 0.181 RRSL_02465 Transcriptional regulators, LysR family638721275 10.98330487 11.64757245 1.436 down 0.04 RRSL_02483 2-methylcitrate synthase( EC:2.3.3.5,EC:4.1.3.31 )638721302 11.09802987 11.68267245 1.359 down 0.186 RRSL_02512 Putative osmotically inducible lipoprotein B1 transmemberane-related protein638721314 11.92105487 11.85402245 1.155 up 0.173 RRSL_01742 Hypothetical Protein638721315 11.33045487 11.86167245 1.309 down 0.00906 RRSL_01743 Hypothetical Protein638721316 10.77910487 11.33649745 1.333 down 0.0594 RRSL_01744 Hypothetical Protein638721318 9.817254869 9.910672449 1.034 up 0.891 RRSL_01746 Hypothetical Protein638721319 7.636279869 8.064872449 1.22 down 0.245 RRSL_01747 Hypothetical Protein638721320 11.34207987 10.55074745 1.909 up 0.0419 RRSL_01748 Hypothetical Protein

638721321 8.949579869 9.922072449 1.778 down 0.0706 RRSL_01749 Atypical orf638721331 11.45830487 11.21102245 1.309 up 0.0935 RRSL_01759 possible Phospholipase D638721332 12.25867987 11.79659745 1.519 up 0.00469 RRSL_01760 Hypothetical Protein638721333 10.81965487 10.87292245 1.063 up 0.823 RRSL_01761 Hypothetical Protein638721334 11.85297987 12.17439745 1.132 down 0.514 RRSL_01763 Hypothetical Protein638721335 13.59722987 14.13214745 1.313 down 0.0199 RRSL_01764 hypothetical conserved secreted protein638721337 7.423204869 7.836722449 1.207 down 0.345 RRSL_01767 Transcriptional regulators, LysR family638721338 7.168529869 7.720797449 1.329 down 0.185 RRSL_01768 argC ArgC( EC:1.2.1.38 )638721441 13.37227987 14.59069745 2.109 down 0.0582 RRSL_01930 Hypothetical Protein638721469 12.00362987 12.16864745 1.016 down 0.925 RRSL_01961 lolC LolC638721471 9.720804869 8.599747449 2.399 up 0.0893 RRSL_02576 hypothetical protein638721472 10.10052987 10.30642245 1.045 down 0.834 RRSL_02577 Conserved hypothetical protein638721473 9.332379869 9.273047449 1.149 up 0.563 RRSL_02578 putative chromosome segregation ATPases638721474 10.53785487 10.54727245 1.096 up 0.749 RRSL_02579 hypothetical protein638721494 12.22617987 13.09707245 1.657 down 0.153 RRSL_RNA023 ( tRNA )638721503 9.887179869 10.82919745 1.741 down 0.129 RRSL_RNA024 ( tRNA )638721504 11.56217987 11.77477245 1.05 down 0.769 RRSL_02608 hypothetical protein638721505 10.70867987 10.67242245 1.131 up 0.436 RRSL_02609 hypothetical protein638721508 10.15672987 9.889172449 1.327 up 0.25 RRSL_02612 hypothetical protein638721509 8.191729869 8.736797449 1.322 down 0.312 RRSL_02613 Conserved hypothetical protein638721511 12.81322987 12.64559745 1.239 up 0.294 RRSL_02615 hypothetical protein638721512 11.63740487 11.41154745 1.29 up 0.367 RRSL_02617 hypothetical protein638721513 12.93377987 13.06109745 1.01 up 0.964 RRSL_02618 VgrG protein638721514 11.10137987 11.80517245 1.476 down 0.219 RRSL_02619 hypothetical protein638721515 11.65735487 11.97414745 1.129 down 0.705 RRSL_02620 hypothetical protein638721516 10.83762987 11.43274745 1.369 down 0.405 RRSL_02621 hypothetical protein638721517 12.98067987 13.01077245 1.08 up 0.701 RRSL_02622 hypothetical protein638721518 13.56435487 12.79922245 1.874 up 0.00155 RRSL_02623 hypothetical protein638721519 13.64265487 13.38744745 1.316 up 0.0111 RRSL_02624 hypothetical protein638721520 13.39715487 12.78272245 1.688 up 0.0224 RRSL_02625 hypothetical protein638721521 10.85412987 11.28829745 1.224 down 0.6 RRSL_02626 hypothetical protein638721522 8.258954869 8.509472449 1.078 down 0.832 RRSL_02627 hypothetical protein638721523 11.45442987 11.33327245 1.199 up 0.448 RRSL_02628 hypothetical protein638721524 12.67787987 12.23594745 1.498 up 0.0417 RRSL_02630 hypothetical protein possibly involved in aromatic compound catabolism638721546 7.679679869 7.321697449 1.413 up 0.0538 RRSL_01694 Hypothetical Protein638721547 7.449329869 7.125297449 1.381 up 0.168 RRSL_01695 hmuU HmuU638721548 7.556354869 7.580197449 1.085 up 0.689 RRSL_01696 Hemin-binding periplasmic protein hmuT precursor638721554 11.95597987 10.94587245 2.221 up 0.0848 RRSL_01703 Hypothetical Protein638721569 8.499229869 8.105822449 1.449 up 0.342 RRSL_01718 6-aminohexanoate-dimer hydrolase( EC:3.5.1.46 )638721572 8.654804869 7.463322449 2.519 up 0.116 RRSL_01721 Phosphatidylserine decarboxylase( EC:4.1.1.65 )638721573 13.15090487 12.80339745 1.403 up 0.0329 RRSL_01722 Tetracycline resistance protein638721574 7.566054869 7.736547449 1.02 down 0.918 RRSL_01723 Tetracycline resistance protein638721578 7.517804869 7.578697449 1.057 up 0.872 RRSL_01727 DNA-binding protein638721580 9.034154869 7.705897449 2.77 up 0.067 RRSL_01729 Hypothetical Protein638721581 8.588029869 8.054397449 1.596 up 0.202 RRSL_01730 Hypothetical Protein638721588 12.49937987 13.20922245 1.482 down 0.0434 RRSL_01786 Hypothetical Protein638721589 12.17347987 12.94412245 1.546 down 0.0398 RRSL_01787 Hypothetical Protein638721590 10.56710487 11.11574745 1.325 down 0.224 RRSL_01788 Hypothetical Protein638721592 13.71775487 14.36554745 1.42 down 0.176 RRSL_01790 Hypothetical Protein638721593 7.409479869 8.196997449 1.564 down 0.0847 RRSL_01791 Hypothetical Protein638721607 8.781479869 8.386372449 1.45 up 0.218 RRSL_01805 Hypothetical Protein638721609 8.075004869 8.323997449 1.077 down 0.677 RRSL_01807 OM efflux protein (porin)638721610 9.541154869 9.130597449 1.466 up 0.208 RRSL_01809 putative multicoper oxidase638721616 7.574454869 8.592397449 1.835 down 0.0164 RRSL_01816 Hypothetical Protein638721622 6.760804869 7.305197449 1.321 down 0.0801 RRSL_01822 Hypothetical Protein638721628 10.30062987 10.68319745 1.181 down 0.447 RRSL_01828 Hypothetical Protein638721629 10.72087987 10.55887245 1.234 up 0.532 RRSL_01829 Hypothetical Protein

638721683 12.38332987 12.67372245 1.108 down 0.562 RRSL_01201 Cysteine desulfhydrase / Selenocysteine lyase( EC:4.4.1.16 )638721685 14.58127987 14.71109745 1.008 up 0.967 RRSL_01622 Hypothetical Protein638721686 11.09895487 11.05967245 1.133 up 0.55 RRSL_01623 Hypothetical Protein638721705 8.724004869 8.618047449 1.187 up 0.559 RRSL_01642 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein638721707 11.63712987 11.07279745 1.631 up 0.325 RRSL_01646 Fumarylacetoacetase( EC:3.7.1.2 )638721714 10.17952987 10.43974745 1.085 down 0.641 RRSL_01653 Hypothetical Protein638721733 10.07755487 10.56227245 1.268 down 0.13 RRSL_01672 Transcriptional regulator638721745 11.56440487 9.240647449 5.522 up 0.0721 RRSL_01542 Alkanesulfonates-binding protein638721787 8.397554869 8.416547449 1.088 up 0.628 RRSL_01589 Hypothetical Protein638721788 9.592129869 9.473197449 1.197 up 0.468 RRSL_01590 Hypothetical Protein638721790 16.15317987 16.40674745 1.08 down 0.51 RRSL_01593 Hypothetical Protein638721800 9.804454869 10.00307245 1.04 down 0.839 RRSL_01603 6-aminohexanoate-dimer hydrolase( EC:3.5.1.46 )638721810 10.59507987 11.20337245 1.381 down 0.0152 RRSL_01614 3-oxoacyl-[acyl-carrier protein] reductase( EC:1.1.1.100 )638721837 11.79532987 12.17392245 1.178 down 0.499 RRSL_02021 Hypothetical Protein638721847 14.19615487 13.60249745 1.664 up 0.0454 RRSL_02032 Hypothetical Protein638721848 11.32370487 11.01627245 1.365 up 0.0522 RRSL_02032_5 Hypothetical Protein638721857 12.47820487 13.27449745 1.574 down 0.199 RRSL_01389 Bacterial Protein Translation Initiation Factor 2 (IF-2)638721882 13.28810487 13.21719745 1.158 up 0.16 RRSL_01413 Hypothetical Protein638721885 12.99025487 12.97389745 1.115 up 0.556 RRSL_01417 Hypothetical Protein638721902 10.05650487 10.65584745 1.373 down 0.0671 RRSL_01362 DNA helicase638721903 10.94062987 11.69017245 1.523 down 0.0719 RRSL_01363 Predicted hydrolases or acyltransferases638721907 11.71412987 13.27842245 2.68 down 0.117 RRSL_01367 Bile acid-inducible operon protein F638721909 8.402504869 9.836422449 2.449 down 0.0599 RRSL_01369 Acyl-CoA dehydrogenase( EC:1.3.99.- )638721910 8.183204869 8.736947449 1.33 down 0.546 RRSL_01370 Transporter, MFS superfamily638721918 7.173929869 7.716047449 1.319 down 0.0325 RRSL_01379 Hypothetical Protein638721919 7.357329869 7.492222449 1.004 up 0.984 RRSL_01380 possible Phage replication protein CRI.638721920 7.990254869 8.413947449 1.215 down 0.0909 RRSL_01381 Hypothetical Protein638721921 8.454479869 8.588972449 1.005 up 0.985 RRSL_01382 Vpf77-like protein638721922 8.921854869 8.029372449 2.047 up 0.0808 RRSL_01383 Hypothetical Protein638721923 9.852804869 8.701122449 2.451 up 0.0672 RRSL_01384 Hypothetical Protein638721924 7.302429869 7.812347449 1.29 down 0.0948 RRSL_01385 Possible Zonular occludens toxin (Zot).638721925 13.36620487 14.10424745 1.511 down 0.0319 RRSL_01387 Hypothetical protein638721926 9.832279869 10.78904745 1.759 down 0.0431 RRSL_01388 Hypothetical Protein638721927 16.84622987 17.07837245 1.064 down 0.202 RRSL_RNA048 5S ( rRNA )638721934 8.942054869 9.356347449 1.207 down 0.15 RRSL_01969 Acetylornithine deacetylase( EC:3.5.1.16 )638721945 10.66330487 10.60674745 1.147 up 0.0924 RRSL_01981 Outer membrane porin protein 32 precursor638721975 8.475279869 8.347172449 1.205 up 0.311 RRSL_01125 Hypothetical Protein638721978 11.24020487 11.07412245 1.237 up 0.113 RRSL_01129 Hypothetical Protein638721986 9.497154869 9.826997449 1.139 down 0.268 RRSL_01137 hypothetical protein638721987 9.339779869 9.707772449 1.169 down 0.489 RRSL_01138 hypothetical protein638721988 8.473704869 7.968072449 1.566 up 0.139 RRSL_01139 Possible pyrimidine reductase638721989 8.476754869 8.944197449 1.253 down 0.286 RRSL_01140 Possible GTP cyclohydrolase II( EC:3.5.4.25 )638721990 9.618404869 10.16814745 1.326 down 0.0867 RRSL_01141 hypothetical protein638721991 8.450579869 9.380247449 1.726 down 0.0151 RRSL_01142 possible transcriptional regulator638721992 8.800954869 8.276247449 1.587 up 0.021 RRSL_01143 Dihydrodipicolinate synthase( EC:4.2.1.52 )638721993 12.15885487 10.17904745 4.351 up 0.0979 RRSL_01144 Hypothetical Protein638722002 11.23577987 11.43997245 1.044 down 0.63 RRSL_01331 smc Smc638722010 9.736829869 10.71257245 1.782 down 0.000189 RRSL_01341 Hypothetical Protein638722012 9.607529869 10.47314745 1.651 down 0.0311 RRSL_01343 Acriflavin resistance plasma membrane protein638722025 10.66977987 10.80402245 1.005 up 0.979 RRSL_01047 possible transposase638722041 15.28625487 15.49452245 1.047 down 0.737 RRSL_01065 Hypothetical Protein638722048 7.519704869 7.346497449 1.243 up 0.0481 RRSL_01073 ybtQ YbtQ638722051 8.958504869 7.878947449 2.331 up 0.0585 RRSL_01077 Hypothetical Protein638722053 9.541054869 8.762322449 1.892 up 0.0615 RRSL_01249 adenine DNA methyltransferase-like protein638722054 7.950479869 7.581597449 1.424 up 0.207 RRSL_01250 Hypothetical Protein638722063 10.20280487 10.01039745 1.26 up 0.148 RRSL_01261 Transcriptional regulators, LysR family638722064 9.259729869 10.03037245 1.546 down 0.135 RRSL_01262 hypothetical protein

638722066 8.802354869 8.881347449 1.044 up 0.876 RRSL_01264 Antibiotic biosynthesis monooxygenase638722068 9.577979869 10.36327245 1.562 down 0.0146 RRSL_01266 Hypothetical Protein638722076 6.685004869 7.552997449 1.654 down 0.00601 RRSL_01274 Outer membrane porin protein 32 precursor638722077 12.42782987 13.26054745 1.614 down 0.0609 RRSL_01275 Outer membrane porin protein 32 precursor638722082 12.59385487 13.60012245 1.82 down 0.263 RRSL_RNA016 ( tRNA )638722109 11.07530487 10.52307245 1.617 up 0.0213 RRSL_01035 hypothetical protein638722110 11.27297987 11.10534745 1.239 up 0.0829 RRSL_01036 hypothetical protein638722121 9.223354869 8.541097449 1.77 up 0.0115 RRSL_01206 parB ParB638722125 10.19580487 10.53559745 1.147 down 0.282 RRSL_01210 Hypothetical Protein638722126 11.85850487 12.11884745 1.085 down 0.678 RRSL_01211 Hypothetical Protein638722162 8.643279869 8.567972449 1.162 up 0.383 RRSL_01490 Dibenzothiophene desulfurization enzyme C638722172 9.319104869 8.769372449 1.614 up 0.167 RRSL_01501 Hypothetical Protein638722199 13.62057987 13.36489745 1.317 up 0.232 RRSL_RNA019 ( tRNA )638722202 8.293654869 8.131497449 1.234 up 0.592 RRSL_01530 Hypothetical Protein638722203 15.47750487 15.55612245 1.044 up 0.793 RRSL_01286 Hypothetical Protein638722204 9.845104869 9.624772449 1.285 up 0.043 RRSL_01287 Hypothetical Protein638722238 9.211679869 8.857947449 1.409 up 0.128 RRSL_01452 Acetoacetyl-CoA reductase( EC:1.1.1.36 )638722241 9.059529869 8.698947449 1.416 up 0.251 RRSL_01455 Citrate-proton symporter638722242 11.61062987 10.98437245 1.702 up 0.156 RRSL_01456 Citrate-proton symporter638722245 11.41055487 12.35904745 1.749 down 0.00256 RRSL_01459 Hypothetical Protein638722248 9.311629869 8.188647449 2.402 up 0.0954 RRSL_01462 Hypothetical Protein638722254 9.978404869 10.18914745 1.049 down 0.766 RRSL_01468 Hypothetical Protein638722256 7.149029869 7.337672449 1.033 down 0.931 RRSL_01470 Hypothetical Protein638722258 7.998654869 7.671722449 1.383 up 0.143 RRSL_01472 ADA regulatory protein / O6-methylguanine-DNA methyltransferase( EC:2.1.1.63 )638722262 9.451004869 9.872947449 1.214 down 0.296 RRSL_01476 Hypothetical Protein638722290 8.067179869 8.421372449 1.158 down 0.406 RRSL_01097 Shikimate kinase( EC:2.7.1.71 )638722302 9.145204869 9.331897449 1.031 down 0.864 RRSL_01113 Hypothetical Protein638722303 13.12945487 13.29282245 1.015 down 0.781 RRSL_00918 Predicted metal-dependent hydrolase638722310 11.83652987 11.59389745 1.305 up 0.154 RRSL_00927 Hypothetical Protein638722341 8.197604869 7.412072449 1.901 up 0.173 RRSL_00818 Hypothetical Protein638722344 9.063379869 9.805647449 1.516 down 0.0154 RRSL_00821 Acriflavin resistance plasma membrane protein638722345 9.216379869 9.786747449 1.345 down 0.00351 RRSL_00822 Acriflavin resistance plasma membrane protein638722346 9.146879869 9.889872449 1.517 down 0.022 RRSL_00823 Hypothetical Protein638722347 11.08567987 11.73167245 1.418 down 0.011 RRSL_00824 Possible Outer Membrane Efflux Pump638722354 8.759029869 8.952797449 1.036 down 0.812 RRSL_00831 Possible transcriptional regulators, LysR family638722357 9.469279869 10.37647245 1.699 down 0.0137 RRSL_00834 Hypothetical protein638722358 10.17385487 10.18899745 1.091 up 0.57 RRSL_00835 Probable transglutaminase-like enzymes, putative cysteine proteases638722359 9.989604869 9.527572449 1.519 up 0.0999 RRSL_00835_1 Possible hydrolase (HAD superfamily)638722360 8.554729869 8.196722449 1.413 up 0.0118 RRSL_00836 Possible Metal dependent amidase/aminoacylase/carboxypeptidase638722363 12.79140487 11.87347245 2.084 up 0.12 RRSL_00840 Hypothetical Protein638722364 9.277379869 9.359097449 1.042 up 0.861 RRSL_00951 MobA-like protein638722365 10.66922987 10.40754745 1.322 up 0.168 RRSL_00952 Hypothetical Protein638722366 12.79752987 12.16519745 1.71 up 0.0109 RRSL_00958 Hypothetical protein638722367 12.30267987 11.87669745 1.482 up 0.0372 RRSL_00959 ATPase, AAA family638722368 9.777879869 10.50657245 1.502 down 0.144 RRSL_00960 ATPase, AAA family638722391 10.04182987 10.24604745 1.044 down 0.787 RRSL_00769 Hypothetical protein638722430 8.490179869 7.664147449 1.955 up 0.0512 RRSL_00703 Hypothetical protein638722434 10.61815487 10.33842245 1.339 up 0.176 RRSL_00707 Probable transcriptional regulator, MarR family638722435 10.58537987 10.62184745 1.075 up 0.845 RRSL_00711 Transcriptional regulators, LysR family638722436 10.01797987 7.952997449 4.616 up 0.0829 RRSL_00712 Muconate cycloisomerase( EC:5.5.1.1 )638722437 8.040454869 8.019572449 1.119 up 0.806 RRSL_00713 Muconolactone delta-isomerase( EC:5.3.3.4 )638722439 12.17805487 12.12229745 1.146 up 0.26 RRSL_00886 Hypothetical Protein638722440 11.58685487 12.27559745 1.461 down 0.118 RRSL_00887 Hypothetical Protein638722441 14.43360487 14.46534745 1.079 up 0.405 RRSL_00888 putative cytochrome P450638722442 8.425654869 8.461647449 1.076 up 0.829 RRSL_00889 Hypothetical Protein638722443 7.379204869 8.006697449 1.4 down 0.0515 RRSL_00890 Transposase638722466 13.74555487 13.98064745 1.066 down 0.845 RRSL_RNA015 ( tRNA )

638722467 13.58950487 13.77559745 1.031 down 0.916 RRSL_RNA014 ( tRNA )638722468 13.34147987 13.44532245 1.026 up 0.932 RRSL_RNA013 ( tRNA )638722469 16.85155487 17.04199745 1.034 down 0.224 RRSL_RNA044 16S ( rRNA )638722472 16.85370487 17.02472245 1.02 down 0.417 RRSL_RNA046 23S ( rRNA )638722473 16.88125487 17.08204745 1.041 down 0.0928 RRSL_RNA047 5S ( rRNA )638722474 13.79735487 14.00827245 1.049 down 0.784 RRSL_01429 Isrso10638722476 10.14960487 9.795947449 1.409 up 0.145 RRSL_01431 RTX family calcium-binding cytotoxins and bacteriocins638722477 9.875804869 9.981697449 1.025 up 0.895 RRSL_01432 RTX family calcium-binding cytotoxins and bacteriocins638722479 7.115379869 8.065422449 1.751 down 0.0139 RRSL_01434 Acetyltransferase( EC:2.3.1.- )638722480 7.962079869 8.146097449 1.029 down 0.919 RRSL_01435 Hypothetical Protein638722490 11.27895487 11.86912245 1.364 down 0.0428 RRSL_01445 Hypothetical Protein638722494 11.93735487 11.39599745 1.605 up 0.0299 RRSL_01449 ABC transporter substrate-binding protein638722502 10.66417987 11.72917245 1.896 down 0.00119 RRSL_00987 Hypothetical cytosolic protein638722512 13.34532987 12.40924745 2.11 up 0.104 RRSL_00998 Hypothetical protein638722540 14.26815487 15.18149745 1.707 down 0.0244 RRSL_00880 Hypothetical Protein638722547 15.93522987 16.31532245 1.179 down 0.18 RRSL_RNA011 ( tRNA )638722548 16.61182987 16.74074745 1.008 up 0.936 RRSL_RNA010 ( tRNA )638722551 11.42895487 12.45837245 1.85 down 0.145 RRSL_RNA009 ( tRNA )638722594 9.657579869 9.773222449 1.018 up 0.916 RRSL_00590 Hypothetical Protein638722595 9.628604869 10.12287245 1.276 down 0.0468 RRSL_00591 Hypothetical protein638722596 8.542729869 9.401622449 1.643 down 0.0272 RRSL_00592 VgrG protein638722597 10.66935487 11.49184745 1.603 down 0.0605 RRSL_00593 Hypothetical Protein638722598 11.85560487 11.37849745 1.535 up 0.173 RRSL_00442 Hypothetical protein638722599 10.94285487 10.25502245 1.777 up 0.0353 RRSL_00443 Homoserine O-acetyltransferase( EC:2.3.1.31 )638722602 11.48117987 11.45204745 1.125 up 0.57 RRSL_00446 Hypothetical Protein638722603 11.83280487 11.97872245 1.002 down 0.986 RRSL_00447 Probable methyltransferase( EC:2.1.1.- )638722604 8.851104869 10.01809745 2.035 down 0.065 RRSL_00448 Hypothetical protein638722606 9.828054869 9.926047449 1.03 up 0.912 RRSL_00450 Branched-chain amino acid aminotransferase( EC:2.6.1.42 )638722618 10.91920487 10.86037245 1.149 up 0.134 RRSL_00464 Hypothetical Protein638722637 7.838479869 7.850372449 1.094 up 0.744 RRSL_00484 Wall-associated protein precursor638722659 8.262779869 8.556372449 1.111 down 0.554 RRSL_00528 hypothetical protein638722661 11.77885487 11.48977245 1.347 up 0.111 RRSL_00530 Hypothetical protein638722668 8.831279869 8.173472449 1.74 up 0.108 RRSL_00538 Poly(3-hydroxyalkanoate) depolymerase( EC:3.1.1.- )638722676 11.15830487 10.32844745 1.96 up 0.0117 RRSL_00546 Hypothetical protein638722685 9.737679869 10.59717245 1.644 down 0.00482 RRSL_00747 Hypothetical Protein638722686 10.21675487 10.22032245 1.1 up 0.773 RRSL_00748 Transcriptional regulator638722687 9.016029869 7.924572449 2.35 up 0.172 RRSL_00749 czcA CzcA638722688 7.705154869 8.252497449 1.324 down 0.313 RRSL_00750 czcB CzcB638722694 8.875254869 8.760372449 1.194 up 0.265 RRSL_00757 Hypothetical protein638722699 9.359254869 8.900922449 1.515 up 0.0464 RRSL_00635 Hypothetical protein638722700 8.309554869 9.006647449 1.469 down 0.245 RRSL_00637 Hypothetical protein638722701 10.56372987 10.64874745 1.04 up 0.895 RRSL_00640 Core protein638722702 8.739179869 9.391072449 1.424 down 0.208 RRSL_00641 Hypothetical Protein638722703 13.45280487 12.97454745 1.536 up 0.0171 RRSL_00642 Hypothetical Protein638722704 9.820229869 10.44289745 1.395 down 0.185 RRSL_00643 Hypothetical Protein638722708 8.017904869 8.787397449 1.545 down 0.143 RRSL_00647 Hypothetical protein638722716 8.573879869 9.234422449 1.432 down 0.003 RRSL_00790 Two component system histidine kinase( EC:2.7.3.- )638722717 8.900929869 9.322097449 1.213 down 0.0684 RRSL_00791 Hypothetical Protein638722720 9.859879869 9.518422449 1.397 up 0.536 RRSL_00793 Hypothetical protein638722733 12.80500487 13.25267245 1.236 down 0.00574 RRSL_00808 Hypothetical Protein638722734 10.69075487 10.67914745 1.112 up 0.525 RRSL_00809 Hypothetical Protein638722735 12.74290487 13.24312245 1.282 down 0.0537 RRSL_00594 hypothetical protein638722736 10.23817987 9.650022449 1.658 up 0.189 RRSL_00595 hypothetical protein638722740 7.735979869 7.906647449 1.02 down 0.934 RRSL_00598 hypothetical protein638722743 10.45312987 11.33882245 1.674 down 0.00633 RRSL_00602 hypothetical protein638722744 9.592104869 10.07144745 1.263 down 0.0609 RRSL_00603 4-carboxymuconolactone decarboxylase( EC:4.1.1.44 )638722751 11.88057987 11.08954745 1.908 up 0.173 RRSL_00610 Glycosyl transferases group 1

638722753 9.385929869 9.133922449 1.313 up 0.279 RRSL_00419 Hypothetical protein638722754 12.40910487 11.94017245 1.526 up 0.00887 RRSL_00420 Integrase/Recombinase638722755 8.955979869 9.261922449 1.12 down 0.356 RRSL_00421 Hypothetical Protein638722756 6.994604869 7.586797449 1.366 down 0.0547 RRSL_00422 Hypothetical Protein638722758 8.985954869 8.839397449 1.221 up 0.388 RRSL_00424 Hypothetical Protein638722759 10.48322987 11.06517245 1.356 down 0.0542 RRSL_00425 Possible Flavoredoxin FLR638722763 10.73877987 10.91179745 1.021 down 0.906 RRSL_00429 Hypothetical protein638722769 7.426804869 7.114672449 1.369 up 0.0721 RRSL_00435 Hypothetical Protein( EC:1.3.1.55 )

638722770 6.950079869 7.211147449 1.086 down 0.683 RRSL_00437Benzoate 1,2-dioxygenase electron transfer component / Toluate 1,2-dioxygenase electron transfer component( EC:1.14.12.-,EC:1.14.12.10 )

638722771 10.66532987 8.861497449 3.851 up 0.0793 RRSL_00438 Probable benzoate 1,2-dioxygenase beta subunit( EC:1.14.12.10 )638722773 8.013954869 7.276297449 1.839 up 0.124 RRSL_00440 Catechol 1,2-dioxygenase( EC:1.13.11.1 )638722774 11.79560487 12.68414745 1.678 down 0.0689 RRSL_00441 Hypothetical Protein638722776 16.53630487 16.72307245 1.031 down 0.539 RRSL_00368 Hypothetical Protein638722777 7.328079869 7.285272449 1.136 up 0.563 RRSL_00369 transposase638722790 8.746704869 9.052922449 1.12 down 0.681 RRSL_00382 HIPA protein638722796 14.06712987 13.37512245 1.782 up 0.109 RRSL_00390 Hypothetical Protein638722798 9.069579869 9.029097449 1.134 up 0.472 RRSL_00393 Hypothetical protein638722801 7.070279869 7.580522449 1.291 down 0.168 RRSL_00396 Polyprenyl-phosphate beta-D-glucosyltransferase( EC:2.4.1.78 )638722802 9.726254869 8.207922449 3.16 up 0.0636 RRSL_00397 Hypothetical protein638722817 11.31680487 10.64902245 1.752 up 0.116 RRSL_00416 Hypothetical Protein638722819 8.151154869 7.569797449 1.65 up 0.0656 RRSL_00489 siderophore biosynthesis protein638722820 7.066879869 7.707972449 1.413 down 0.0321 RRSL_00490 2,3-dihydroxybenzoate-AMP ligase( EC:2.7.7.58 )638722832 10.62045487 10.82862245 1.047 down 0.724 RRSL_00350 Hypothetical Protein638722833 8.218604869 8.468972449 1.078 down 0.675 RRSL_00351 Probable mannose-6-phosphate isomerase638722836 13.99615487 13.68094745 1.372 up 0.231 RRSL_RNA008 ( tRNA )638722839 11.22057987 9.493647449 3.651 up 0.0521 RRSL_00355 C-5 sterol desaturase( EC:1.3.- )638722843 8.961129869 7.950072449 2.223 up 0.105 RRSL_00360 Hypothetical Protein638722848 12.71450487 12.37444745 1.396 up 0.0876 RRSL_00551 Hypothetical Protein638722864 13.64657987 14.02152245 1.175 down 0.796 RRSL_00612 Cold shock protein638722894 7.300529869 7.379022449 1.044 up 0.729 RRSL_00283 Possible histone Acetyltransferase GNAT fam.638722895 8.460154869 7.965972449 1.553 up 0.0393 RRSL_00285 D-3-phosphoglycerate dehydrogenase( EC:1.1.1.95 )638722897 8.213854869 8.627372449 1.207 down 0.0731 RRSL_00288 Hypothetical protein638722898 8.711354869 8.376997449 1.39 up 0.105 RRSL_00289 D-nopaline dehydrogenase( EC:1.5.1.19 )638722902 11.92467987 12.38309745 1.245 down 0.238 RRSL_00309 Hypothetical Protein638722905 7.298104869 8.117447449 1.599 down 0.0411 RRSL_00312 Hypothetical Protein638722906 7.740654869 8.220847449 1.264 down 0.212 RRSL_00313 Hypothetical protein638722908 11.95690487 12.85694745 1.691 down 0.121 RRSL_00315 Tryptophan synthase alpha chain( EC:4.2.1.20 )638722909 10.85845487 11.73672245 1.666 down 0.0292 RRSL_00317 Hypothetical protein638722910 10.02445487 10.14452245 1.015 up 0.922 RRSL_00319 Possible phosphohydrolases638722911 8.184754869 8.082172449 1.184 up 0.302 RRSL_00320 Acriflavin resistance plasma membrane protein638722912 7.962379869 8.131147449 1.018 down 0.899 RRSL_00321 Hypothetical Protein638722913 8.454654869 8.903897449 1.237 down 0.152 RRSL_00322 Possible outer membrane protein638722914 11.09035487 10.64372245 1.503 up 0.0626 RRSL_00324 Hypothetical protein638722915 10.56222987 10.79279745 1.063 down 0.651 RRSL_00323 phage related protein/predicted endonuclease638722918 13.05370487 13.23319745 1.026 down 0.914 RRSL_RNA005 ( tRNA )638722935 8.005404869 7.407322449 1.669 up 0.0601 RRSL_00326 hypothetical protein638722940 10.54525487 10.09517245 1.507 up 0.116 RRSL_00332 Hypothetical Protein638722950 8.619554869 8.308647449 1.368 up 0.189 RRSL_00221 Short chain dehydrogenase( EC:1.- )638722951 7.774254869 7.812747449 1.074 up 0.714 RRSL_00222 Hypothetical protein638722967 8.772954869 8.908522449 1.004 up 0.979 RRSL_00238 Hypothetical protein638722970 8.203004869 8.218797449 1.091 up 0.799 RRSL_00245 Hypothetical Protein638722990 9.823554869 8.297747449 3.176 up 0.0702 RRSL_00180 Hypothetical Protein638722994 8.540304869 8.894222449 1.158 down 0.294 RRSL_00185 Transcriptional regulators, LysR family638722995 8.001654869 8.690047449 1.46 down 0.0852 RRSL_00186 Possible beta-lactamase type II638723001 14.64847987 14.67119745 1.085 up 0.559 RRSL_00192 Transposase638723002 10.23115487 9.020647449 2.553 up 0.069 RRSL_00166 Hypothetical Protein

638723003 7.647979869 7.846072449 1.039 down 0.844 RRSL_00167 Hypothetical Protein638723033 8.830154869 9.006947449 1.024 down 0.922 RRSL_00195 3-oxoacyl-[acyl-carrier protein] reductase( EC:1.1.1.100 )638723034 8.923504869 9.222197449 1.114 down 0.331 RRSL_00196 Possible transcriptional regulator of sugar metabolism638723035 7.734004869 7.737222449 1.1 up 0.608 RRSL_00197 Hypothetical protein638723037 8.639354869 8.009697449 1.706 up 0.0505 RRSL_00199 Probable pyrodoxal phosphate biosynthesis protein638723038 7.376354869 7.411047449 1.076 up 0.64 RRSL_00200 Probable iron containing alcohol dehydrogenase II638723040 10.54335487 9.033997449 3.14 up 0.0703 RRSL_00202 Hypothetical Protein638723043 13.16125487 13.20297245 1.071 up 0.324 RRSL_00158 Core protein638723044 12.73380487 13.32679745 1.367 down 0.149 RRSL_00160 VgrG protein638723045 7.908379869 8.025672449 1.017 up 0.949 RRSL_00163 Transposase638723046 15.91932987 15.97984745 1.057 up 0.584 RRSL_00165 Hypothetical Protein638723070 15.26407987 15.44862245 1.03 down 0.855 RRSL_00092 Hypothetical Protein638723071 10.85900487 11.16099745 1.117 down 0.544 RRSL_00093 Hypothetical protein638723078 9.445029869 8.473672449 2.163 up 0.0606 RRSL_00115 Hypothetical Protein638723080 14.96342987 15.33437245 1.172 down 0.44 RRSL_00120 Hypothetical Protein638723084 7.048654869 7.335047449 1.105 down 0.479 RRSL_00128 Probable oxidoreductase638723085 10.12015487 8.755447449 2.841 up 0.0815 RRSL_00130 Possible periplasmic iron-binding protein638723086 7.869954869 7.536447449 1.39 up 0.211 RRSL_00131 Possible phosphonoacetaldehyde hydrolase( EC:3.11.1.1 )638723090 9.125629869 7.793522449 2.777 up 0.0689 RRSL_00108 Transcriptional regulators, LysR family638723092 7.188954869 7.331797449 1 down 0.997 RRSL_00110 Hypothetical protein638723099 10.11037987 11.12522245 1.831 down 0.0118 RRSL_00077 Undecaprenyl-phosphate alpha-4-amino-L-arabinosyltransferase( EC:2.7.8.- )638723123 12.04817987 11.21337245 1.967 up 0.0104 RRSL_00065 Hypothetical Protein638723124 7.748804869 7.080072449 1.753 up 0.177 RRSL_00059 hypothetical membrane protein638723125 7.589829869 7.485872449 1.185 up 0.44 RRSL_00060 Peptide synthetase638723129 8.168929869 8.238922449 1.05 up 0.648 RRSL_00043 Shikimate kinase( EC:2.7.1.71 )638723132 9.837229869 9.443522449 1.449 up 0.119 RRSL_00017 Hypothetical protein638723135 8.088354869 7.666797449 1.477 up 0.118 RRSL_00047 Hypothetical Protein638723138 8.096354869 7.841422449 1.316 up 0.239 RRSL_00041 Hypothetical Protein638723140 9.928604869 10.72284745 1.571 down 0.0479 RRSL_00026 probable enoyl-[acyl-carrier-protein] reductase (NADH)( EC:1.3.1.9 )638723141 9.327704869 10.16657245 1.621 down 0.0877 RRSL_00027 Probable acetate kinase638723142 10.36350487 11.23327245 1.656 down 0.0971 RRSL_00028 Probable phosphate acetytransferase( EC:2.3.1.19,EC:2.3.1.8 )638723143 8.935929869 10.22767245 2.219 down 0.0853 RRSL_00029 Hypothetical protein638723148 8.261579869 9.009972449 1.522 down 0.0674 RRSL_00019 NAD(FAD)-utilizing dehydrogenases638723154 6.311879869 6.891622449 1.354 down 0.0933 RRSL_00004 NAD(P)H dehydrogenase (quinone)( EC:1.6.99.2 )638723155 6.107254869 6.503247449 1.192 down 0.0297 RRSL_00005 Phosphatidylglycerophosphatase A( EC:3.1.3.27 )638723157 8.827479869 8.167197449 1.743 up 0.131 RRSL_00002 Hypothetical Protein

fc – Gene belongs to the R. solonaceraum Core Genome, as defined by Guidot et al. (19) and personal communication from B. Remenant and P. Prior

aMicroarray gene ID tag from custom-designed chipbGene absolute expression values were based on four biological replicates, normalized using the Robust Multichip Algorithm as described under Methods.cDirection of expression difference in planta relative to in bacteria at comparable cell densities in culture. Genes were considered differentially expressed if the difference in normalized gene expression values was greater than 2-fold at a P-value <0.05. Genes significantly up- and downregulated are labeled in orange and blue, respectively.dProbabilistic statistical analysis (Student’s t-test) was used to identify differentially expressed (DE) genes. After selection of candidate DE genes, a P-value was calculated for each gene. The false discovery rate (FDR, Benjamini Hochberg) adjustment for multiple testing correction was applied to the P- value to reduce the number of false positives and to increase the chances of identifying all the differentially expressed genes.

eo –Gene belongs to the set of strain UW551-GMI1000 orthologs were defined as pair-wise best BLAST hits between the UW551 and GMI1000 genomes that also have >70% amino acid identity over >70% of the protein.

Documents

Ralstonia solanacearum UW551 in planta and in rich …mbio.asm.org/content/suppl/2012/07/11/mBio.00114-12.DCSupplement… · Supplemental Table1A: Expression patterns of Ralstonia