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QUICKSEE: QUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins, William E. Higgins, 1,2 1,2 Krishnan Ramaswamy, Krishnan Ramaswamy, 1 1 Geoffrey McLennan, Geoffrey McLennan, 2 2 Eric A. Hoffman, Eric A. Hoffman, 2 2 Roderick Swift Roderick Swift 1 1 1 1 Penn State University, University Park, PA 16802 Penn State University, University Park, PA 16802 2 2 University of Iowa, Iowa City, IA 52246 University of Iowa, Iowa City, IA 52246 RSNA '96 RSNA '96 -- -- infoRAD infoRAD , Chicago, IL, 1 December 1996 , Chicago, IL, 1 December 1996

QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

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Page 1: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE:QUICKSEE:Virtual-Endoscopic System for

Interactive Navigation and Detailed Quantitation

William E. Higgins,William E. Higgins,1,21,2 Krishnan Ramaswamy,Krishnan Ramaswamy,11

Geoffrey McLennan,Geoffrey McLennan,22 Eric A. Hoffman,Eric A. Hoffman,22 Roderick SwiftRoderick Swift11

11Penn State University, University Park, PA 16802Penn State University, University Park, PA 1680222University of Iowa, Iowa City, IA 52246University of Iowa, Iowa City, IA 52246

RSNA '96 RSNA '96 ---- infoRADinfoRAD, Chicago, IL, 1 December 1996, Chicago, IL, 1 December 1996

Page 2: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Acknowledgments:

Research supported by grants from:

Whitaker Foundation Whitaker Foundation ------ Biomedical Engineering GrantBiomedical Engineering Grant

National Cancer Institute of the NIH, grant CA53607.National Cancer Institute of the NIH, grant CA53607.

NSF NSF ------ Biological Instrument Devel., grant BIR9317816Biological Instrument Devel., grant BIR9317816

Page 3: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

infoRAD Exhibit Goals:1. Appreciate virtual endoscopy's 1. Appreciate virtual endoscopy's potentialpotential for 3D for 3D

thoracic image assessment thoracic image assessment

Page 4: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

infoRAD Exhibit Goals:2. Understand the “enhanced awareness” afforded by 2. Understand the “enhanced awareness” afforded by

virtualvirtual endoscopy over endoscopy over traditionaltraditional endoscopyendoscopy

Page 5: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

infoRAD Exhibit Goals:3. Realize need for 3. Realize need for automatic image analysisautomatic image analysis

to make virtual endoscopy truly usefulto make virtual endoscopy truly useful

Page 6: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE: QUICKSEE: virtualvirtual--endoscopic software systemendoscopic software system

1. 3D thoracic analysis 1. 3D thoracic analysis

Page 7: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE: QUICKSEE: virtualvirtual--endoscopic software systemendoscopic software system

2 . Provides many 2 . Provides many pictorialpictorial and and quantitativequantitative tools: tools:

a. Visualize airways a. Visualize airways

b. Get measurements (crossb. Get measurements (cross--sectional area)sectional area)

Page 8: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE: QUICKSEE: virtualvirtual--endoscopic software systemendoscopic software system

3. Automatic or manual navigation 3. Automatic or manual navigation

a. use automatically computed paths a. use automatically computed paths

b. create one yourselfb. create one yourself

Page 9: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Virtual Endoscopy Virtual Endoscopy ------ IdeaIdea

Input a highInput a high--resolution 3D radiologic image resolution 3D radiologic image

virtual copy of anatomyvirtual copy of anatomy

Use computer to explore virtual anatomy Use computer to explore virtual anatomy

permits unlimited navigation explorationpermits unlimited navigation exploration

Page 10: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE --- basic operation1. Load:1. Load:

3D radiologic image3D radiologic image(optional) 3D path data(optional) 3D path data

Page 11: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE --- basic operation

2. Automatic Mode: 2. Automatic Mode:

Automatically compute: Automatically compute: paths (axes) paths (axes)

extracted regions (airways)extracted regions (airways)

Page 12: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

QUICKSEE --- basic operation

3. Interactive Mode: 3. Interactive Mode:

View, Edit, Create pathsView, Edit, Create paths

View structures; get quantitative dataView structures; get quantitative data

Page 13: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Case 1:

Dog LungDog Lung

Page 14: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

1. View automatically computed airway axes 1. View automatically computed airway axes on reference projections.on reference projections.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 15: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

2. See Virtual Endoscopic View and 2D Slices.2. See Virtual Endoscopic View and 2D Slices.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 16: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

3. See quantitative data and local 2D 3. See quantitative data and local 2D crosscross--sections.sections.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 17: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

4. See Oblique slices along airway.4. See Oblique slices along airway.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 18: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

5. See plot of lumen diameter along 5. See plot of lumen diameter along airway extent.airway extent.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 19: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

6. See a straightened “Tube View” along 6. See a straightened “Tube View” along airway.airway.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 20: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

7. See Virtual Endoscopic movie along airway.7. See Virtual Endoscopic movie along airway.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 21: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

8. MPEG recording of Virtual Endoscopic 8. MPEG recording of Virtual Endoscopic movie along airway.movie along airway.

Case 1:Case 1:Dog Bronchial TreeDog Bronchial Tree

Page 22: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Example 2:

Lung Cancer PatientLung Cancer Patient

Page 23: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

1. Get automatically computed paths.1. Get automatically computed paths.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Page 24: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

2. See lumen diameter along airway path.2. See lumen diameter along airway path.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Page 25: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

3. View straightened “Tube View” 3. View straightened “Tube View” along airway.along airway.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Note severe narrowingNote severe narrowingdue to cancer.due to cancer.

Page 26: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

4. View oblique slices along airway.4. View oblique slices along airway.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Page 27: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

5. See local cross5. See local cross--sections at cancer site.sections at cancer site.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Note severe narrowingNote severe narrowingdue to cancer.due to cancer.

Page 28: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

6. See global 2D slice at cancer site.6. See global 2D slice at cancer site.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Note severe narrowingNote severe narrowingdue to cancer.due to cancer.

Page 29: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

7. See Endoscopic Movie along 7. See Endoscopic Movie along diseased airway.diseased airway.

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Page 30: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Case 2:Case 2:Lung Cancer PatientLung Cancer Patient

Page 31: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Case 3:Healthy HumanHealthy Human

Complete Lung ScanComplete Lung Scan

Page 32: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

1. Get automatically computed paths.1. Get automatically computed paths.

Case 3:Case 3:Healthy HumanHealthy Human

Page 33: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

2. See Tube View along airway.2. See Tube View along airway.

Case 3:Case 3:Healthy HumanHealthy Human

Page 34: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Sagittal...Sagittal...

3a. View 2D Global Slices at a site3a. View 2D Global Slices at a site

Case 3:Case 3:Healthy HumanHealthy Human

Page 35: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

3b. View 2D Global Slices at a site3b. View 2D Global Slices at a site

Coronal...Coronal...

Case 3:Case 3:Healthy HumanHealthy Human

Page 36: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

Transverse...Transverse...

3c. View 2D Global Slices at a site3c. View 2D Global Slices at a site

Case 3:Case 3:Healthy HumanHealthy Human

Page 37: QUICKSEE - LabQUICKSEE: Virtual-Endoscopic System for Interactive Navigation and Detailed Quantitation William E. Higgins,1,2 Krishnan Ramaswamy,Krishnan Ramaswamy,1 Geoffrey McLennan,2

4. If desired, navigate through lungs yourself!4. If desired, navigate through lungs yourself!