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Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded by the Department of Health and Human Services, Office of the National Coordinator for Health Information Technology under Award Number IU24OC000013.

Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

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Page 1: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Quality Improvement

Decision Support for Quality Improvement

Lecture b

This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded by the Department of Health and Human Services, Office of the National Coordinator for Health Information Technology under Award Number IU24OC000013.

Page 2: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Decision Support for Quality Improvement

Learning Objective─Lecture b

• Analyze the benefits and shortfalls of alerts and clinical reminders.

2Health IT Workforce Curriculum Version 3.0/Spring 2012

Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 3: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Reminders and Alerts

“…the burden of reminders and alerts must not be too high…or alert fatigue may cause clinicians to override both important and unimportant alerts, in a manner that compromises the desired safety effect of integrating decision support into CPOE.” (Van der Sijs, et al., 2006)

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Improvement Lecture b

Page 4: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Alerts and Reminders

Nuisance Alert• “…provides little

perceived benefit to the prescriber at the time of the alert”

Alert Fatigue• “…arise when clinicians,

either consciously or unconsciously, begin to systematically bypass CDS alerts without regard to their importance, enabling the possibility that a clinically important alert is missed” (Chaffee, B.W., 2010)

4Health IT Workforce Curriculum Version 3.0/Spring 2012

Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 5: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Responses to Clinical Reminders

5Health IT Workforce Curriculum Version 3.0/Spring 2012

Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 6: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Responses to Clinical Reminders

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Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 7: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Four Types of Alerts/Reminders

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Improvement Lecture b

Page 8: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Basic Drug Alerts

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Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 9: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Advanced Drug Alerts

9Health IT Workforce Curriculum Version 3.0/Spring 2012

Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 10: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Evidence to Support Drug Alerts

• Systematic review examined 20 studies that evaluated the impact of efficacy of computerized drug alerts and prompts– 23 of 27 alert types identified demonstrated

benefit • Improving prescribing behavior• Reducing error rates

– Greatest potential for affecting prescribing• Drug-drug interaction alerts• Drug-disease contraindication alerts• Dosing guidelines based on age

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Improvement Lecture b

Page 11: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Improving Adoption of Drug Alerts

• Shah & colleagues studied improving clinician acceptance of drug alerts in ambulatory care– Designed a selective set of drug alerts for the ambulatory

care setting using a criticality leveling system– Minimized workflow disruptions by designating only critical

to high-severity alerts to be interruptive to clinician workflow

• Alert levels: – 1: clinician could not proceed with the prescription without

eliminating the contraindication– 2: clinician could proceed if provided an override reason – 3: alert displayed at top of screen in red; did not hinder

workflow

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Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 12: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Basic Laboratory Alerts

12Health IT Workforce Curriculum Version 3.0/Spring 2012

Quality Improvement Decision Support for Quality

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Page 13: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Evidence to Support Lab Alerts

• Research examined the impact of a CDDS that generated reminders of previous lab test results

• Found that the proportion of unnecessarily repeated tests dropped significantly

• Features of the Alert– Alert was automatically prompted and was part of the

clinician workflow– User could not deactivate the alert output– Most recent laboratory result for viral serology test and its

date was automatically retrieved from the patient’s EHR– Alert was displayed at the time and location of decision

making (before the user ordered an unnecessarily repeated test)

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Page 14: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Practice Reminders

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Page 15: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Practice RemindersChallenges

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Page 16: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Administrative Reminders

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Page 17: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Decision Support for Quality Improvement

Summary—Lecture b• Alerts/reminders have the potential to improve

patient safety.

• Types include drug and lab test alerts, practice reminders, and administrative reminders.

• Nuisance alerts provide little perceived benefit to the prescriber at the time of the alert, causing clinician frustration and alert fatigue.

• Successful alerts are specific, sensitive, clear, concise and support clinical workflow, allowing for safe, efficient responses.

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Page 18: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Decision Support for Quality Improvement

References—Lecture bReferences• Chaffee, B.W. Future of clinical decision support in computerized prescriber order entry. American Journal of

Health System Pharmacists. 67: 932-935. 2010. • De Clercq, P.A., Blom, J.A., Hasman, A., Korsten, H.H.M. A strategy for developing practice guidelines for the ICU

using automated knowledge acquisition techniques. Journal of Clinical Monitoring. 15:109-117. 1999. • Kuperman, G,J,, Bobb, A., Payne, T.H., et al. Medication-related clinical decision-support in computerized

provider order entry systems: a review. Journal of the American Medical Informatics Association. 14(1), 29-40. 2007.

• Lami, J.B., Ebrahiminia ,V., Riou C., et al. (2010). How to translate therapeutic recommendations in clinical practice guidelines into rules for critiquing physician prescriptions. Methods and application to five guidelines. BMC Medical Informatics and Decision Making. 2010 May 28;10:31.

• Metzger, J., Macdonald, K. Clinical decision support for the independent physician practice. Health Reports, California Health Care Foundation. 2002.

• Nies, J., Colombet, I., Zapleta,l E., et al. Effects of automated alerts on unnecessarily repeated serology tests in cardiovascular surgery department: a time series analysis. BMC Health Services Research. 10:70. 2010

• Porter, S. Primary care associations release joint principles for accountable care organizations. Available from:

http://www.aafp.org/online/en/home/publications/news/news-now/professional-issues/20101118acojointprinciples.html

• Schedlbauer, A., Prasad, V, Mulvaney, C, et al. What evidence supports the use of computerized alerts and prompts to improve clinicians' prescribing behavior? Journal of the American Medical Informatics Association. 16(4):531-8. 2009.

• Shah, N.R., Seger, A.C., Seger, D.L., et al. Improving Acceptance of Computerized Prescribing Alerts in Ambulatory Care. Journal of the American Medical Informatics Association 2006; 13(1): 5–11. 2006. 18Health IT Workforce Curriculum

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Page 19: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Decision Support for Quality Improvement

References─Lecture bReferences• Shah, N.R., Seger, A.C., Seger, D.L., et al. Improving Acceptance of Computerized Prescribing Alerts in

Ambulatory Care. Journal of the American Medical Informatics Association 2006; 13(1): 5–11. 2006.• Teich, J.M., Merchia, P.R., Schmiz, J.L., et al. Effects of computerized physician order entry on prescribing

practices. Arch Intern Med. 2000 Oct 9; 160 (18):2471-7)• Van Der Sijs, H., Aarts, J., Vulto, A., Berg, M. Overriding of drug safety alerts in computerized physician order

entry. Journal of the American Medical Informatics Association. 2006; 13(2), 138-147. • Vashitz, G., Meyer, J., Parmet, Y., Peleq, R., et al. Defining and measuring physicians' responses to clinical

reminders. Journal of Biomedical Informatics. 2009; 42(2):317-26. • Zanetti, G., Flanagan, H.L. Cohn, L.H. et al. Improvement of intraoperative antibiotic prophylaxis in prolonged

cardiac surgery by automated alerts in the operating room, Infect Control Hosp Epidemiol 24 (1) (2003), pp. 13–16.

Images

Slide 5: Responses to Clinical Reminders. Adapted by Dr. Anna Maria Izquierdo-Porrera from Vashitz, G., Meyer J, Parmet, Y, et al. (2009). Defining and measuring physicians' responses to clinical reminders. Journal of Biomedical Informatics 42(2):317-26. Epub 2008 Oct 26

Slide 6: Responses to Clinical Reminders. Adapted by Dr. Anna Maria Izquierdo-Porrera from Vashitz, G., Meyer J, Parmet, Y, et al. (2009). Defining and measuring physicians' responses to clinical reminders. Journal of Biomedical Informatics 42(2):317-26. Epub 2008 Oct 26

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Quality Improvement Decision Support for Quality

Improvement Lecture b

Page 20: Quality Improvement Decision Support for Quality Improvement Lecture b This material (Comp12_Unit5b) was developed by Johns Hopkins University, funded

Decision Support for Quality Improvement

References─Lecture b

Images

Slide 7: Four Types of Alerts/Reminders. Dr. Anna Maria Izquierdo-Porrera

Slide 8: Basic Drug Alerts. Adapted by Dr. Anna Maria Izquierdo-Porrera from Kuperman, G.J., Bobb, A., Payne, T.H., et al. Medication-related clinical decision-support in computerized provider order entry systems: a review. Journal of the American Medical Informatics Association 14(1), 29-40. 2007.

Slide 9: Advanced Drug Alerts. Dr. Anna Maria Izquierdo-Porrera

Slide 12: Basic laboratory Alerts. Dr. Anna Maria Izquierdo-Porrera

Slide 14: Practice Reminder Challenges. Adapted by Dr. Anna Maria Izquierdo-Porrera from Lami, J.B., Ebrahiminia, V., Riou, C., et al. (2010). How to translate therapeutic recommendations in clinical practice guidelines into rules for critiquing physician prescriptions. Methods and application to five guidelines. BMC Medical Informatics and Decision Making. 2010 May 28;10:31.

Slide 15: Practice Reminders. Dr. Anna Maria Izquierdo-Porrera

Slide 16: Administrative Reminders. Dr. Anna Maria Izquierdo-Porrera

20Health IT Workforce Curriculum Version 3.0/Spring 2012

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Improvement Lecture b