Prof John Connell, Head of TAHSCProf Jill Belch, R&D DirectorDr Keith Gillon, Senior R&D Manager

Scottish Academic Health Sciences

Collaboration(SAHSC)

• Scottish Government initiative• Four nodes: East, West, South and North• Aim to raise international research profile, excellence & competitiveness

• Focus for clinical academic development• Streamlining pathway for high quality research: Industry and Council/Charity funded

TAyside medical Sciences Centre(TASC)

•Joint development between NHS Tayside and University of Dundee

•Scope/expectation to include other Boards and institutions. Could include eg

• NHS Fife

• St Andrew’s University

• Abertay

• NHS Forth Valley

• Stirling University

• Scottish Crop Research Unit

NHS Academics CommitteeChair: James Ferguson

TASC BoardUoD:PrincipalVPDean, MedicineHead of Planning, CMDNNHS Tayside:CEOCOOFinance Director

• Research strategy of TAHSC Node• Research Governance• MHRA Inspections• National Targets and Opportunities

TASC Executive Group

• Implementation of strategy• Operational Management• Financial Governance

SAHSC• National Oversight Board• Rapid Response Group

Research Governance

Research Governance CommitteeChair: Margaret Smith

University of DundeeCourt

Clinical Trials Unit Collaboration

CRC/Training & StaffTrial ManagementData Management (in collaboration with Health Informatics/DEBU)

R&D office

Governance ApprovalsRisk Assessment

BDM/CommercialLegalIPFinance/CostingsCSO Liaison

TASC Operational

Managers Team

Imaging

NHS Tayside Board

Biorepository/Tissue Bank

Networks/Speciality Groups

Quality Assurance

AuditStandardsPharmacovigilanceIMP Handling

Scientific Steering CommitteeChair: Allan Struthers

Trial Management

• Tayside Clinical Trials Unit (TCTU)– Start up (SOPs/Guidelines, Contracts &

Agreements, Insurance)– Venue (CRC and other)– Running (Trial Management, Data, Stats)– Close down (notifications, archiving etc)

• UKCRF Registered CRC

Experience & own infrastructure

Information and training. Mentoring and support of trial managers as required. Facilitation and support. Potential funding sources.

Advice on design and execution. Network of Trialists. Programming, statistical guidance, randomisation etc

Experience & limited

infrastructure

Full trial management, data management etc

No experience & no infrastructure

Potential funding sources.

Infomatics/Data Management***

•Dundee Epidemiolgy and Biostatistics Unit (DEBU)•Health Infomatics Centre (HIC)

•Tayside Clinical Trials Unit•Data processors n=2•Statisticians n=2

TASC• Costings• Research Governance• Training• CRC• CTU• Imaging• Tissue management• Ethics• Sponsorship

Funders• Industry• Charities• Councils etc

One stop shop

Investigators

TASC Offices

•School of Nursing

•Level 3, Residency ‘C’ Block

•Move in middle of April

•Advice/help for all areas of clinical research

Polyclinics

Main Wards

LaboratoriesTheatre

block

SouthBlock

Polyclinics

Main Wards

LaboratoriesTheatre

block

SouthBlock

We are here!

Research Resource Centre•Wireless internet connections

•Some desk tops for ‘hot desking’

•Will evolve:• Specialist literature• Specialist software

+ + TASC =

Research ‘Clinics’ from May 2010

•Jointly organised TASC, Tayside REC, SHIL

• Representatives from R&D office, TCTU, DEBU, REC and other groups

• Advice on regulations, scientific design, data management, approvals, ethical issues, IP

•Last Wednesday of every month

•TASC offices, Level 3 Residency Block

•Combination appointments and ‘drop-in’

•Research clinics outwith Ninewells

–Dental Hospital–Perth Royal Infirmary–Stracathro

•One Outreach clinic per month on rotational basis

•Combination appointments and ‘drop-in’

Outreach Research Clinics

TASC Research Training Programme

•Training events advertised on website

•Already established: - GCP training, GLP training, TCTU Seminars with SOP training

•New courses coming soon- GMP for IMP- IRAS

•Principal information source for TASC–Web pages for all TASC functions–Research clinics–Training programmes–SOPs

• ‘Live’ at 5pm 3rd March 2010

•Evolving–Suggestions for content welcome

Website www.tasc-research.org.uk

How TASC Operates:

TAyside medical Sciences

CentreCollaboration

Providing service to

clinical researchers and Funding

Partners

University of Dundee NHS Tayside

Data handling & management.

Statistical advice

Imaging, CVDDiabetes, Cancer

NeuroscienceInflammation,

Populations etc

Statistics/clinical trial

design/methdology***

Trial Management Governance ***

Sponsorship

HIC/DEBU**

Imaging***Tissue Bank***

*** CSO Scottish Lead/Co-Lead

New Frontiers in Research and Teaching

TASC

To boldly go