PROBLEM-BASED

LEARNING SIMULATION

Similar to the TV Show “House”

CASE Anyone want to read this? A 30 year-old white female lab

technician who lives in Boston, MA presents with an upper respiratory infection, fever, chills, and a rash on her thigh. A week ago, with a group, she took a trip to a camping grounds just outside Boston. She slept outdoors along with the rest of her group. She doesn’t remember being bitten by anything. She is concerned that her rash started small and during the last few days has been spreading. She has no allergies. She had tried an over-the-counter medication, Benadryl, with no rash improvement. Further questioning revealed that she slept on leaves she placed on the grass.

THE RASH

LET US DISCUSS Signs/

Symptoms??? Differential

Diagnosis??? Clinical

Diagnosis??? Treatment??? Write on the

board Why?

CASE (CONT…) She was given a minimal dose of

Tetracycline (broad spectrum). The patient went home. Why?

CASE (CONT…) Two days later, the laboratory results

came back. She was positive for Lyme Disease. Her primary care physician alerted here immediately and increased the dose of her Tetracycline to fight the infection.

WHAT IS LYME DISEASE?

CAUSED BY BACTERIA, BORRELIA Gram-negative

spirochetal bacteria from the genus Borrelia.

They need a vector to transmit itselfLiceTicks

CARRIED BY TICKS

TICK SIZE VARIES, BUT THEY ARE REALLY, REALLY SMALL

LYME DISEASE OVERVIEW

HUMAN CYCLE

LYME DISEASE OVERVIEW CONT.

LIFECYCLE

TREATMENT OUTCOME – THE GOOD Good if detected

early.

TREATMENT OUTCOME – THE BAD Untreated, can

cause many problems, affected many organs.Brain.Nerves.Eyes. Joints.Heart.

LYME DISEASE TOTAL CASES

PREVENTION

YOUR TURN FOR PROBING QUESTIONS??? Speaker: Manpreet Singh Email: msing001@ucr.edu

Speaker: Marizabel Orellana

Email: morel001@ucr.edu

Speaker: Vanessa Correa Email: vcorr001@ucr.edu