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Gruppo Prof. Anna Maria Papini e Prof. Paolo Rovero
Unità di ricerca interdipartimentaleLaboratorio di Chimica e Biologia di Peptidi e Proteine
Email: [email protected], [email protected]
Purification of biomolecules, peptides,
proteins
Screening and
biological
characterization
Autism Spectrum
Disorders
In Collaboration with:
AUTOIMMUNE MEDIATE DISEASES
Department of Pharmaceutical and Toxicological Chemistry, University of Naples ‘‘Federico II’’ (A. Carotenuto, E. Novellino)Department of Pharmaceutical Sciences, University of Salerno (AM. D’Ursi)Toscana Biomarkers Srl, Siena (MC. Alcaro)Istituto di Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia, Neuroimmunology Unit (L Battistini, G Borsellino)Department of Neurological Sciences and Vision, University of Verona, Ospedale Policlinico (G.B. Rossi, B. Bonetti, L. Lovato)Laboratory of BioMolecules, UPMC- CNRS-ENS, Paris (F. Burlina, S Lavielle)Institut de Chimie Moleculaire (ICMUB, UMR CNRS 5260), University of Burgundy (S. Jugè)University of Milan Clinical Immunology, Humanitas Clinical and Research Center and University of California (C. Selmi)CNR ISTM, Padova (P.Traldi)University of Padova, Department of Sci. Med. & Chirurg. (A. Lapolla)Laboratory for Translational Research, Harvard Medical School and Department of Medicine, Brigham and Women’s Hospital, Boston (M. Chorev)Neurologie, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, and LINC, Université de Strasbourg-CNRS (J.de Seze and É. Trifilieff)MIT Massachusetts Institute of Technology (B. Imperiali)
METABOLIC DISORDERS and AUTISM SPECTRUM DISORDERS
Child Neuropsychiatry Unit, University Hospital AOUS of Siena (J. Hayke)Neonatal Intensive Care Unit, University Hospital AOUS of Siena (C. De Felice)Clinical Physiology Institute (IFC-CNR), National Research Council of Italy, Lecce Section, & Division of Neonatology, Perrino Hospital (Giuseppe Latini)Clinica Pediatrica e Dipartimento età evolutiva, University Hospital of Parma, Italy (S. Bernasconi, ME. Street) Bracco Foundation (E.Grossi)
CULTURAL HERITAGE
Chemistry Department University of Florence (L Dei, M.Potenza, L. Rosi)Earth Sciences Department University of Siena (A. Atrei, E. Gaggelli, I. Memmi, N. Marchettini, D. Valensin, G. Valensin)
MOLECULAR STRUCTURES TO TARGETING TUMOR CELLSEuropean Institute of Oncology
Optimized strategies for the
synthesis of bio molecules
PeptLab
Metabolic
disorders
This infrastructure is characterized by a strong know-how in organic and medicinal chemistry, in
chemical biology, in synthesis as well as purification of small biomolecules, peptides, proteins and
molecular and biological characterization
Multi-disciplinary technology
platform for research in
life science
Molecular structures to
targeting tumor cells
Microwave Synthesizer Explorer S Class (CEM) for organic synthesis
Automated microwave peptide synthesizer Liberty (CEM)
Multiple-Peptide Automatic Synthesizer APEX 396 (Advanced
ChemTech)
Ultra Fast HPLC + ESI-MS
AktaBasic Liquid Chromatography System
(GE Healthcare) for protein purification
ACQUITY™ UPLC system (Waters) coupled with aMicromass® Q-Tof MICROTM mass spectrometer(Waters) equipped with an ESI source
FACS per analisi di cellule
Biacore T100 (GE Healthcare)
EspiKem S.r.l.
c/o Polo Scientifico
Via Ugo Schiff n.6
Tel: 055 4573724
Fax: 055 4573584
e-mail: [email protected]
ESPIKEM S.R.L.EspiKem Srl is a Contract Research Organization, founded in2003 as a spin-off of the University of Florence, specialized inthe field of design, synthesis, purification andcharacterization of peptides (also from natural sources) andtheir analogues of biomedical interest.
TECHNOLOGY TRANSFER
TOSCANA BIOMARKERS S.R.L.Toscana Biomarkers S.r.l. is aresearch and development companydedicated to the discovery andvalidation of new tests for diagnosisand follow-up of autoimmunediseases.
Cultural
Heritage
Cosmeceutical
peptides
Autoimmune
mediate
diseases
As a proof-of-concept we started organising two Research Units:PeptLab@UCP, a platform of the University of Cergy-Pontoise, located in the Laboratory of Chemical Biology EA4505 of the Department of
Chemistry of the University of Cergy-Pontoise (France);PeptLab@Unifi, located in the Department of Chemistry "Ugo Schiff" and the Department NEUROFARBA (Department of Neurosciences,
Psychology, Drug Research and Child Health) of the University of Florence (Italy)