April 2015 Issue 5

PREP NEWSletter

Chief Investigator

Professor Khalid Khan

Project lead

Professor Shakila

Thangaratinam

Senior Trials Manager

Dr Julie Dodds

Research Assistant

Sian Newton

Data Assistant

Malika Barakat

Welcome to the nal edion of the PREP newsleer. In

this issue, we will provide an update on the study and

outline the next steps to close out the study at sites.

Study Coordinator

John Allotey

Thank you for your outstanding contribution and for all your hard work on

the PREP study. We have had the involvement of 51 hospitals and their re-

search teams who recruited more than one thousand women to the study.

We had very little losses to follow up and are extremely pleased to announce

that data entry and data cleaning for the PREP study is now complete! It

would not have been possible without your much appreciated hard work and

co-operation. Thank you especially for helping us with the final stages of data

querying for the PREP follow-up forms and close-out calls.

The last paent was recruited on the 31st of April 2014

Data cleaning and querying completed with the help of research mid-

wives and research teams at parcipang sites

Close out teleconferences held for all parcipang sites in preparaon

for archiving

The REC and sponsor have been noed on the study end

Data analysis, model development and internal validaon has been

completed

The nal HTA report is due on 14th of May 2015

Sites can now proceed with archiving of study documents

Study update

Website: www.blizard.qmul.ac.uk/research-genera*on/324-prep

An extra special...

Womens Health Research Unit

CPCPH, Blizard Instute

Barts and The London

School of Medicine and Denstry

Yvonne Carter Building

58 Turner Street

London E1 2AB

0207 882 6048

Page 1

Page 2 PREP NEWSletter

Facts and figures

Archiving

Follow us on twitter!

PREP sites

Basingstoke

Birmingham City

Birmingham Womens

Blackpool Victoria

Bradford Royal Inrmary

Chestereld Royal

City General

Cumberland Inrmary

Derriford

Furness General

Glan Clwyd

James Cook

Kings Mill

Leeds General Inrmary

Leicester Royal Inrmary

Leighton

Lincoln County

Liverpool Womens

New Cross

Newham University

North Devon District

No>ngham City

Pilgrim

Queen Alexandra, Portsmouth

Queen Elizabeth, Gateshead

Queens, Burton

Queens, Romford

Queens Medical Centre

Royal Cornwall

Royal Free

Royal London

Royal Shrewsbury

Royal Victoria Inrmary

Russells Hall

Singleton

Southend

St. Georges

Staordshire General

Sunderland Royal

UHCW

University of Wales

Wansbeck

Warrington

Warwick

West Cumberland

West Middlesex Univ.

Wexham Park

Whipps Cross

Worcestershire Royal

York

Keep an eye out for updates on PREP and other trials at the

Womens Health research unit on Twier (using

#prepstudy) on the Katherine Twining Network Twier

page @KT_Network

We can now proceed with archiving

of study documents at site. If not

already done so, please provide the

study oce with details of where

local archiving will be.

The PREP study is the largest study on women with early onset pre-

eclampsia

53 sites open to the study with 51 sites recruing at least 1 paent

3302 paents screened for inclusion in the study

1106 eligible women recruited to the study

8 parcipants lost to follow up

PREPTASTIC Quizzes

Use the clues to think of the words that contain PREP. 1) Not in a ready enough state for a task. (13 letters) _ _ _ _ _ _ _ _ _ _ _ _ _ 2) To be of greater number or importance. (12 letters) _ _ _ _ _ _ _ _ _ _ _ _ 3) To take place before feeding. (11 letters) _ _ _ _ _ _ _ _ _ _ _ 4) A sum of money given prior to receiving the goods. (10 letters ) _ _ _ _ _ _ _ _ _ _ 5) To take on the American fashion trend associated with private universities. (6 letters) _ _ _ _ _ _

PREP hospital site anagrams. 1) Poets Win Backlash 2) Hail Moose Jackpots 3) Sly Watchdog Nip All 4) Pilgrims hot Pail 5) Pile Hot Thousands

Quiz Solutions: Underprepared, Preponderate, Preprandial, Prepayment, Preppy Wansbeck Hospital, James Cook Hospital, Glan Clwyd Hospital, Pilgrim Hospital, Southend Hospital

Thank you to Action on Pre-Eclampsia We would also like to express our thanks to APEC, a UK charity dedicated to raising awareness of pre-eclampsia and have continually supported the PREP

study. www.apec.org.uk