British Journal of Urology (1998), 82, 587 POINT OF TECHNIQUE Povidone iodine used as a sclerosing agent in the treatment of chyluria T.V. SHANMUGAM, J.V.S. PRAKASH and G. SIVASHANKAR Department of Urology, Chennai Medical College, Chennai, India Cystoscopy revealed chylous eAux from the left ureteric Indications orifice in three patients and from the right in two. About 8–10 mL of povidone iodine was instilled using a ureteric Chyluria is a recurrent problem in tropical countries; the disease is characterized by remission and exacer- catheter. All five patients were free of symptoms after 6 months of follow-up. bation. The outpatient procedure commonly used is the endoscopic instillation of silver nitrate into the chylous eAuxing ureter, where it acts as a sclerosant. Although Advantages the procedure enjoys wide popularity, it is not without attendant side-eCects like pain and interstitial nephritis. Povidone iodine has the following advantages; it provides a nontoxic, non-irritating, nonvolatile and nonstaining To circumvent these problems, we used povidone iodine as a sclerosant. form of iodine; it has local sclerosant action as well as antiseptic, antibacterial and antifungal actions; it is cheap and easily available; and it is easy to dilute to the Methods required concentration. There were no complications after instillation, e.g. pain, fever, sepsis and interstitial Povidone iodine is an iodine complex with the non-ionic surfactant polymer polyvinyl pyrrolidone; it is water- nephritis. soluble and releases iodine slowly. Povidone iodine 0.2% (0.02% iodine w/v) for use as a sclerosant in treating chyluria is prepared as a 155 dilution of stock solution (2 mL of 5% povidone iodine plus 8 mL of distilled water) Authors in distilled water. Five patients have been treated to date; T.V. Shanmugam, MS, MCh(Uro), Addl. Professor of Urology. J.V.S. Prakash, MCh, Postgraduate in Urology. all underwent a routine physical examination and all G. Sivashankar, MCh, Postgraduate in Urology. tested positively for chyle in the urine. None of the Correspondence: Professor T.V. Shanmugam, Addl. Professor patients had bacterial growth from urine samples in of Urology, Department of Urology, Chennai Medical College & culture and all had normal renal functional values, Govt. General Hospital, Chennai – 600 003, India. albumin:globulin ratio and normal findings on IVU. 587 © 1998 British Journal of Urology

Povidone iodine used as a sclerosing agent in the treatment of chyluria

Download PDF Report

Upload
shanmugam
View
216
Download
1

Embed Size (px)

Citation preview

Page 1: Povidone iodine used as a sclerosing agent in the treatment of chyluria

British Journal of Urology (1998), 82, 587

POIN T OF TECHNIQU E

Povidone iodine used as a sclerosing agent in the treatment ofchyluriaT.V. SHANMUGAM, J.V.S. PRAKASH and G. SIVASHANKARDepartment of Urology, Chennai Medical College, Chennai, India

Cystoscopy revealed chylous eAux from the left uretericIndicationsorifice in three patients and from the right in two. About8–10 mL of povidone iodine was instilled using a uretericChyluria is a recurrent problem in tropical countries;

the disease is characterized by remission and exacer- catheter. All five patients were free of symptoms after 6months of follow-up.bation. The outpatient procedure commonly used is the

endoscopic instillation of silver nitrate into the chylouseAuxing ureter, where it acts as a sclerosant. Although Advantagesthe procedure enjoys wide popularity, it is not withoutattendant side-eCects like pain and interstitial nephritis. Povidone iodine has the following advantages; it provides

a nontoxic, non-irritating, nonvolatile and nonstainingTo circumvent these problems, we used povidone iodineas a sclerosant. form of iodine; it has local sclerosant action as well as

antiseptic, antibacterial and antifungal actions; it ischeap and easily available; and it is easy to dilute to theMethodsrequired concentration. There were no complicationsafter instillation, e.g. pain, fever, sepsis and interstitialPovidone iodine is an iodine complex with the non-ionic

surfactant polymer polyvinyl pyrrolidone; it is water- nephritis.soluble and releases iodine slowly. Povidone iodine 0.2%(0.02% iodine w/v) for use as a sclerosant in treatingchyluria is prepared as a 155 dilution of stock solution(2 mL of 5% povidone iodine plus 8 mL of distilled water) Authorsin distilled water. Five patients have been treated to date; T.V. Shanmugam, MS, MCh(Uro), Addl. Professor of Urology.

J.V.S. Prakash, MCh, Postgraduate in Urology.all underwent a routine physical examination and allG. Sivashankar, MCh, Postgraduate in Urology.tested positively for chyle in the urine. None of theCorrespondence: Professor T.V. Shanmugam, Addl. Professorpatients had bacterial growth from urine samples inof Urology, Department of Urology, Chennai Medical College &culture and all had normal renal functional values,Govt. General Hospital, Chennai – 600 003, India.albumin:globulin ratio and normal findings on IVU.