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PMTCT Outcomes Enhanced by Psychosocial Support and Education for Mothers. June 19, 2012 Johannesburg, South Africa. m 2 m Goals. Reduction in early and late transmission of HIV Reduction in maternal mortality associated with HIV Improved RMNCH Empowerment of women - PowerPoint PPT Presentation
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PMTCT Outcomes Enhanced by Psychosocial Support and Education
for Mothers
June 19, 2012Johannesburg, South Africa
m2m Goals
• Reduction in early and late transmission of HIV
• Reduction in maternal mortality associated with HIV
• Improved RMNCH
• Empowerment of women
• Reduction in stigma associated with HIV
m2m Overview
• Operating for over 10 years• Trains and employs women living with HIV
from local communities to provide PMTCT peer education and support
• Serves pregnant women, new mothers & their male partners
• Employed more than 4,000 Mentor Mothers since m2m’s founding
• Employs 1519 staff, in 609 health facilities in 7 countries
Key findings from m2m 2010 and 2011 client cohorts
Gestational age at 1st visit by country: most women present late for care
Kenya Lesotho Malawi South Africa
Swaziland Uganda Zambia Overall0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
7% 8% 7% 5% 5% 6% 5% 6%
49%52% 56%
45% 49% 44% 48% 47%
44% 40% 37%
50% 46% 49% 48% 47%
3rd trimester2nd trimester1st trimester
n=3474 n=751 n=983 n=10435 n=1624 n=308 n=669 N=18244
Uptake of any ARV during pregnancy, by country, 2010 and 2011 Cohorts
Lesotho Zambia Kenya South Africa Swaziland0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
82%77% 75%
53%
65%
83%
77% 75%71%
67%
2010 Cohorts
2011 Cohorts
* UNICEF. (2011). Children and AIDS: Fifth stocktaking Report, 2010. Geneva: UNICEF, UNAIDS, WHO & UNFPA.
*53% Uptake in Low to Middle income
countries
2011: n=771 n=724 n=3568 n=11123 n=1765
2010: n= 1313 n=991 n= 2059 n=4217 n=898
m2m clients receiving more psychosocial support report higher uptake of ARV during pregnancy
m2m Kenya* m2m Lesotho**
2 m2m visits 3 m2m visits 4+ m2m visits Kenya National Comparison
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
76%
85%
94%
73%
2 m2m visits 3 m2m visits 4+ m2m visits Lesotho National Comparison0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
82%
89%
96%
64%
*X2 =399.09, p<.001 **X2 =71.33, p<.001
n-=781 n=499 n=871 n-=164 n=127 n=242
Coefficients and odds ratio from logistic regression of uptake of any antenatal ARV amongst m2m clients in 2011
B S.E. 95% C.I. for EXP(B)
Lower Odds ratios Upper
Disclosure Not yet disclosed* 1 Disclose to anyone 1.14** .04 2.89 3.14 3.40
Done CD4 testNo* 1Yes .66** .04 1.77 1.93 2.10Came as a CoupleNo* 1Yes .09 .10 0.90 1.10 1.33Knowledge of Male partner status
No* 1Yes .39** .05 1.34 1.47 1.62Gestational at 1st visit 1st Trimester* 1 2nd Trimester .38** .08 1.25 1.46 1.713rd Trimester 1.32** .08 3.19 3.75 4.40Number of m2m antenatal visits
1 m2m visit* 1 2+ m2m visits .27** .05 1.19 1.31 1.443+ m2m visits .83** .07 2.02 2.30 2.624 + m2m visits 1.39** .07 3.52 4.03 4.60*Reference categoryR Square=.17 (Cox & Snell), .25 (Nagelkerke)**P<.001
High Disclosure rates amongst clients receiving psychosocial support in 2010 and 2011 Cohorts
Lesotho Kenya South Africa Swaziland m2m overall 0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
78%
69%
61%
41%
70%
81%
72% 70%
61%
73%
2010 Cohorts2011 Cohorts
2011: n=1579 n=1250 n=5763 n=17200 n=4225 n=32120
2010: n= 1133 n= 2366 n= 4069 n= 4947 n=2573 n=15088
*Uptake of PCR testing amongst m2m clients higher amongst those enrolled earlier in psychosocial
support…
m2m client type overall pattern… m2m Country differentials…
Kenya
Lesotho
Swazila
nd0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
57%50%
32%
73% 70%
58%
seen only after deliveryseen during pregnancy and after delivery
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
37%52%
*Fishers exact test for differences within countries, p<.001
n=12842 n=7200
*Infant PCR test positivity is lower amongst m2m clients enrolled earlier in psychosocial
support…Country Program
Enrolled to m2m after delivery N (%)
Total Enrolled during pregnancy & post deliveryN (%)
Total
Kenya 124 (12) 1038 52 (4) 1306
Lesotho 20 (12) 164 7 (3) 247
Malawi 14 (23) 60 1 (7) 40
South Africa 163 (11) 1456 32 (3) 1031
Swaziland 57 (10) 574 12 (4) 278
Uganda 28 (9) 323 4 (3) 157
Zambia 27 (10) 261 9(9) 98
*m2m overall 433 (11%) 3876 117 (4%) 3157
*Fishers exact test for differences between clients enrolled during pregnancy vs. enrolled post delivery p<.001
Discussion• m2m evidence shows that retention in psychosocial care
improves outcomes• “Dose response” importance of psychosocial visits=health
facility dose• Disclosure key to uptake and adherence of services• Earlier enrolment and follow through in psychosocial
services improve outcomes• Challenges
• Late presentation of women for antenatal care• Implications for retention and initiation in care
• Retention is challenging given inter-health facility movements in health systems
m2m services:• integrated in facilities, promote referrals• generate demand for PMTCT services,
treatment, and care to keep mothers alive
• stigma reduction diminishes demand-side barriers to ARV uptake
Demand Creation and Retention
Retention Initiatives
• Let’s SOAR (Strengthening Outcomes by Analyzing Results): enables site staff to understand data/improve program
• Active Client Follow Up (ACFU): active client follow-up improves client retention in PMTCT cascade through phone calls, SMSes, and/or home visits
1) Daily site-level data collection
2) Quarterly data review and action planning
3) Improve client health!
HOW we ‘SOAR’
m2m Program Department
16
Thank you!