Personalized Healthcare Technology - RIT

Illustration created by Bradley Kwarta (ILLM- '18) for Tom Gaborski, PhD (KGCOE)

Creating a future where healthcare works for everyone Annual Report FY20

Personalized Healthcare TechnologyAnnual Report FY20July 2019 – June 2020

CONTENTSDirectors Statement 3

About the Initiative 4

Strategic Plan 6

A Vision of Growth 8

Accelerating Research 9

Affiliate Publications 10

PHT180 Creative Support and Resources 11

PHT180 Networking Events 12

Researchers 14

Proposals & Awards 16

Featured Research Projects 18

New Research Projects 22

Opportunities for Giving 24

PHT180: Engaging Faculty and Students 26

Publications 27

Illustration created by Evgenia Tranevskaya (VCD '19) for David Borkholder, PhD (KGCOE)

2

DIRECTOR'SSTATEMENT

Imagine if you could build non traditional networks of exceptional talent to tackle healthcare problems in unconventional ways. Could we tap into differing perspectives and different world views to change how we approach problems? Could we proactively link experts in disparate fields to leverage technology in new ways to create innovative healthcare solutions? This idea, and the answers to these questions, form the nucleus of the Personalized Healthcare Technology initiative.

With over 83 affiliated faculty members, representing 9 colleges, PHT180 is a diverse network increasing collaboration across disciplines into new research directions. A major affiliated grant from the National Institutes of Health includes a co-investigator from the College of Art and Design working together with faculty from the Kate Gleason College of Engineering and the Golisano College of Computing and Information Sciences. Faculty from the Saunders College of Business have formed a new collaboration with Engineering and the College of Health Sciences and Technology to engage in healthcare technology research.

Student talent has always been central to the research enterprise, but at PHT180 we are leveraging students from the College of Art and Design, and from the College of Health Sciences and Technology to assist our researchers in conveying concepts

and technical information to both lay and scientific audiences. Students have created over 100 elements of artwork and visualizations for affiliated faculty that are used in proposals, conference presentations, journal publications, and websites. This year our faculty disseminated 103 unique research contributions, including 3 manuscripts that featured RIT student illustrations on the journal cover.

Today we provide a breadth of services to our faculty affiliates including grant development, creative design & development, and grant management resources. This support has helped our active research projects to grow to over $17 million. With new awards in FY20 totaling $5.19 million, and a pipeline of over 54 pending proposals from a growing cadre of faculty, we are poised for explosive growth in healthcare research at RIT. Together, our extraordinary faculty and students are creating a new future where healthcare works for everyone; improved access, reduced cost, and enhanced efficacy.

An engineer, entrepreneur and researcher with expertise in drug delivery and pharmacokinetics, cardiovascular physiology and monitoring, to biosensors and devices. He receives funding from the National Institutes of Health, National Science Foundation, Department of Defense and Industry. Work from his laboratory has resulted in two spin out companies; one focused on wearable technology to aid in triage and treatment of traumatic brain injuries, and the other providing non-invasive cardiovascular assessment in the home.

Advancing Healthcare Research at RITUnconventional teams, entrepreneurial spirit, and technology innovations are transforming the landscape of healthcare access, efficacy, and cost.

David Borkholder, PhD Director, Personalized Healthcare Technology Bausch + Lomb Professor, Microsystems Engineering

3PHT180 Annual Report

Radical collaborations driving healthcare innovation

ABOUT THE INITIATIVE

Personalized Healthcare Technology

PHT180 Annual Report4

DISCOVERopportunities for new partners, sponsors, and grants while being connected with mentors, collaborators, and other talent.1SUPPORTfaculty research through all phases, from ideation to proposal development and grant execution. 2PROMOTEthe individual expertise and success through visual & web assets, media and news.3

PHT180 engaging researchers in new ways

5

STRATEGIC PLAN

6

People ProgramsWhere Creativity Begins Innovating Across the University

National healthcare expenditures are growing at a rate that outpaces that of gross domestic product, and are projected to account for nearly 20% of the US economy by 2028. This unsustainable growth will be further burdened by a doubling of the number of Americans over the age of 65 in the next four decades. The PHT180 initiative is investing in people, programs, places, and partnerships to create a new future in healthcare delivery and individually empowered health to address this national crisis.

Our people come from a wide range of research disciplines, academic programs, and populations. This diversity is central to research that leads to transformative innovations. The PHT180 initiative aims to:

As one of the signature interdisciplinary research areas at RIT, the PHT180 initiative integrates with other university programs to provide opportunities for students, and to elevate success of our faculty. We are:

� integrate student talent across programs into the research enterprise at all levels, leveraging RIT’s strengths in technology, art and design.

� invest in our faculty, providing support services that accelerate research success.

� promote networks and collaboration that lead to new and expanding research directions, and a growing extramurally funded research portfolio.

� partnering with undergraduate and graduate degree programs to integrate research opportunities with the academic experience for students.

� developing a sustainable long-term business model that enables support and services to be expanded to all faculty engaged in healthcare research.

� identifying mechanisms to seed investment in new research directions, removing financial barriers to innovation for our faculty.

PHT180 Annual Report

� defining a central space for creative collaboration and partner engagement; a physical presence that creates identity.

� exploring opportunities to centralize human subjects support including a study coordinator, HIPPA compliant data management, and testing.

7

Places PartnershipsFacilitating Creativity Extending Our Reach and Serving the World

Space creates identity, unity, and when properly designed, stimulates creativity, discovery and collaboration. As healthcare technology research at RIT expands, the PHT180 initiative is:

Partnerships create opportunities for collaborative research, expanded access to clinical study populations, and regional economic development. Expanding partnerships remain a strategic priority for PHT180, specifically to:

� leverage the RRH-RIT Alliance to provide connections and processes that advance RRH as a preferred clinical research partner.

� expand the network at the URMC to connect RIT healthcare researchers with targeted domain expertise.

� coordinate with the Simone Center and Venture Creations to provide healthcare technology expertise to entrepreneurial ventures.

� develop international research partnerships that provide global engagement opportunities for RIT faculty and students.

88

A Vision of GrowthAccelerating healthcare research at RIT

Radical collaborations driving innovation in unconventional ways across campus

Expand student engagement at all levels from undergrad to PhD

Build sustainable healthcare through technology innovations

Emerge as the preeminent institution for applied healthcare research with impact.

8

Double faculty engagement, and achieve $10MM in healthcare research expenditures by 2025

Active Awards

$4.76M

$2.52M

$7.14M

FY17 FY18 FY19 FY20

$8.92M

$24.08M

$1.82M

$4.15M

$12.53M

$29.12M

$27.39M

$17.31M

$5.19M

Proposal Submissions

New Awards

9

Grant Development Support

PHT180 Mentors

Grant Management Support

Curated Grant Opportunities List

Grant Review Committee

ACCELERATING RESEARCHPHT180 provides individual researchers with pre- and post-award resources to grow and manage their research portfolio

PHT180 has a full-time research development specialist who has a PhD in biomedical engineering and past NIH funding experience. He assists faculty members with personalized funding opportunities, establishing new collaborations within and outside of RIT, and in writing and editing of key grant proposal elements.

Experienced researchers offer their time to mentor faculty who are seeking healthcare research grant funding. Mentoring can include grant strategy development, guidance on a particular grant mechanism, refinement of concepts, review of proposals, and best practices in managing an effective research group. https://www.rit.edu/pht180/mentors

Grants management support spans pre- and post-award, and is structured to minimize the program management burden on the PI. The broad scope of these services includes serving as an SRS and SPA collaborative liaison, project financial projections, sponsor reporting, and maintenance of the NIH My Bibliography for the investigator.

A searchable, curated grant opportunities list hosted on the PHT180 website https://www.rit.edu/pht180/grant-opportunities providing faculty with a comprehensive listing of healthcare related funding opportunities.

A committee of established, successful researchers that assists faculty through a pre submission critique with the goal of increasing the quality and scientific rigor of submitted healthcare proposals. https://www.rit.edu/pht180/grant-review-committee

9

Foundations and Development

Biomedical Core Infrastructure

Members of the PHT180 Leadership Team provide proposal development guidance and creative resources for faculty applying to competitive foundation funding opportunities. They also connect RIT Development resources with the right affiliated faculty for site visits and external presentations in support of RIT’s Capital Campaign.

PHT180 provided $80,000 in matching funds towards a $110,000 NYS Empire State Development grant to establish a biomedical research core facility providing centralized, new laboratory equipment to enhance capabilities and accelerate growth in healthcare and biomedical research.


https://www.rit.edu/pht180/mentors

https://www.rit.edu/pht180/grant-opportunities

https://www.rit.edu/pht180/grant-opportunities

https://www.rit.edu/pht180/grant-review-committee

https://www.rit.edu/pht180/grant-review-committee

To view the full list of publications beginning on page 26.

Faculty researchers affiliated with PHT180 and their students have published 69 journal articles, 9 preprints, 23 conference proceedings & abstracts, 1 book chapter, and had 1 utility patent issued in FY20 in the healthcare research domain.

10

PUBLICATIONS AFFILIATE

69Journal articles

23Conferences

1Patent

Design and development teams work on projects for research lab websites, publications, conference materials and proposals. These teams include 13 undergraduate and 8 graduate students from New Media Design, 3D Digital Design, Medical Illustration, Computing & Information Technology, Visual Communication Design and Interactive Games and Media programs. Our students help us to support the research mission of PHT180 across the campus while being exposed to a broad range of research areas.

School of Design and Graduate Visual Communication Design students have worked on over 60 design projects including data visualizations, logos, conference posters, presentation slides, journal article figures, UI designs, web page design changes, diagrams, flow charts, brochures and flyers.

The MAGIC Center, a hub of collaborative spaces and resources at RIT, has provided computer work stations and IT support to the PHT180 student workers and co-ops. The center also provides meeting and event space to PHT180 faculty and staff.

PHT180 provides design, application development, access to an apple developer account and cloud-based services to streamline and advance application development for affiliated faculty members.

Caroline Easton’s avatar application for cognitive behavioral therapy outside the clinic was supported by PHT180 UX/UI resources and provided essential preliminary data which resulted in three proposal submissions totaling over $7.4MM, with one of these awarded at $1.3MM.

PHT180 provides resources to meet the growing need for faculty researchers to have a professional online presence to promote their research. At the close of FY20 PHT180 has created and launched 12 new faculty research lab websites, with another 12 in active development. These websites are actively curated by the student developers, with faculty leveraging the PHT180 resources for content updates, maintenance and technical issues. These websites promote individual faculty and their healthcare technology research.

Website Design and Development Communication Design

Partner Organization

UX/UI Design & Development and Cloud Support

11

PHT180 Creative Support and Resources

Medical Illustration

Medical Illustration students have worked on 20 large illustration projects over the last year which were used in journal articles, websites, promotional materials, videos and three journal covers for faculty Ke Du, and David Borkholder. (see opposite page)

PHT180 initiated a formal relationship with the graduate Medical Illustration program to proactively partner students with PHT180 researchers for development of their thesis portfolio. Five students have partnered with PHT180 in FY20 working on research projects that focus on scoliosis, behavioral drug intervention and therapy, back pain, CRISPR gene editing, and biomechanical imaging of a murine flexor tendon repair model.


PHT180 NETWORKING EVENTS

Healthcare Research Networking Events in FY2020

PHT180 hosts Research Vitals events that provide an informal environment for scientific exchange and networking. During FY20 PHT180 hosted 9 research vitals talks.

We hosted a major Fall event in collaboration with the VP of Research to introduce new faculty and healthcare researchers to the initiative, and to provide an opportunity to establish new research collaborations.

Fundamental to the mission of the initiative is to facilitate collaborative, interdisciplinary networks that grow the healthcare research enterprise at RIT. PHT180 proactively assists affiliated faculty in finding research collaborators to meet specific needs. This includes hosting networking events to facilitate informal interactions with internal and external researchers.

2018 PHT180 networking event with Ben Fry 12

2020 Event Planning & SupportThe Fifth Annual Effective Access Technology Conference

Global Health Conference

The Cerebrovasculature: From Pathophysiology to ModelingDr. Nicola Marchi, CNRS France

OCT 22, 2019

Connecting Healthcare Technology ResearchersRyne Raffelle, RIT OVPR

OCT 1, 2019

PHT180 Research Development SupportTerry Koo, RIT PHT180

NOV 5, 2019

Moving Towards Personalized Therapies for Disc-Related Back PainKarin Wuertz-Kozak, RIT KGCOE

NOV 19, 2019

Human-Machine Interaction for Mental Health CareZhi (Jenny) Zheng, RIT KGCOE

JAN 21, 2019

Quantitative Audio-Visual Sentiment Understanding for in-the-moment Emotion ModulationYu Kong, RIT GCCIS

SEP 17, 2019

PHT180 helped to organize the 2020 Access Technology Conference originally planned for March 17th with Leadership team member Dan Philips.

PHT180 provided support to John Oliphant for the Innovations in Global Health Conference on February 22, 2020.

Mitochondrial Dysfunction in Orthopedic Soft Tissues: New Insights and Opportunities for InterventionMichelle Delco, Cornell University

FEB 4, 2020

Naval Force Health Protection and Other Research Opportunities at the Office of Naval ResearchDr. Timothy Bentley, Office of Naval Research

DEC 3, 2020

Nonparametric Bayesian Modeling Approach and its ApplicationsRui Li, RIT GCCIS

FEB 18, 2020

Ex Vivo Genome Editing as a Therapeutic Approach for Genetic DiseasesRenee Cottle, Clemson University

MAR 3, 2020


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RESEARCHERS

College of Engineering TechnologyHochgraf, ClarkLi, YangmingO'Neil, JenniferRice, Brian

College of Liberal ArtsBaschnagel, JoeEdlund, JohnGodleski, StephanieKothari, AmminaOvesdotter Alm, CeciliaRantanen, EsaStack Whitney, KaitlynWorrell, Tracy

College of ScienceCahill, NathanCraig, Paul Das, MoumitaFerran, MaureenGleghorn, MichaelMalik, NishantMunoz, LauraSchmitthenner, HansSkuse, Gary

Golisano College of Computing and Information SciencesGolen, ErikHoman, ChristopherHu, PeizahoJacobs, StephenKong, YuLi, RuiMkaouer, Mohamed WiemOh, TaeReznik, LeonShi, PengchengWang, LinweiYu, Qi

College of Health Sciences and TechnologyBerbary, CassandraDoolittle, RichardEaston, CarolineOliphant, JohnOrnt, DanielRuder, ElizabethSugarman, LaurenceTrabold, NicoleLohse, Barbara

College of Art and DesignGolden, MaryNae, Hye-JinRemington, Roger

Wood, TimSmith, Adam

PHT180 Leadership Team members are highlighted in orange

83Affiliates

9Colleges

15

National Technical Institute for the DeafBehm, GarySamar, Vincent

ExternalSchwarz, KarlDombovy, Mary

Saunders College of BusinessAkdevelioglu, DuyguBui, QuangHansen, SeanHull, ClydeLiu, ManluMoriuchi, EmiPerotti, Victor JTu, Qiang

Kate Gleason College of EngineeringAbhyankar, VinayBorkholder, DavidBroderick, GordonCarter, BobDay, StevenDu, KeFard, Nasibeh AzadehGaborski, TomKolodziej, JasonKuhl, MichaelLamkin Kennard, KathleenLiberson, AlexLyshevski, Sergey

Proano, RubenPtucha, RaymondPuchades, IvanRashedi, EhsanRichards, MichaelTsouri, GillWuertz-Kozak, KarinZheng, Zhi

Phillips, Dan

MS Students9

18 PhD Students

15 Undergrad Students

CAD, CHST, CLA, COS, GCCIS, KGCOE, SCB

Student Engagement


PROPOSALS & AWARDSThe following metrics are based on people, projects, and proposals formally affiliated with PHT180 in FY20.

Total Active Projects

Projects Total Award Value FY20 Expenditures31 $17.3M $2.37M


Award amount

$250,000

$500,000

$750,000

$1M

$1.25M

$2.25M

$1.5M

$2.5M

$1.75M

$2.75M

$2M

$3M

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PROPOSALS & AWARDSPersonalized Healthcare Technology affiliated new awards total $5.19 Million.

AMO

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Principal Investigator (PD/PI)

0

$400,000

$800,000

$1,200,000

$1,600,000

$2,000,000

$2,400,000

$2,800,000

New Awards in FY20

17

New Proposals Submitted in FY20

54 totaling $27.4M

Wuertz-Kozak

$256

K

Easton

$1.3

M

Abhyankar

$79K

Du

$89K

Borkholder

$2.9

M

Schmitthenner

$95K

Day$3

37K

Swiss National Science Foundation

US Department of Health and Human Services (HRSA).

American Heart Association (AHA) National Aeronautics and Space Administration (NASA)

National Institutes of Health (NIH) National Science Foundation (NSF)

New York State Department of Health (NYSDOH)

Israel Binational Science Foundation

Office of Naval Research

New York State Empire State Development (NYSESD)

Personalized Healthcare Technology Affiliated Projects

Active affiliated awards in FY20 come from a diverse group of healthcare research areas and sponsors.

FEATURED RESEARCH PROJECTS

REU Site: Computational Sensing

Undergraduate researchers will be challenged to make sense of human behaviors and cognitive processes with hardware, software, and complex thinking, exploring the link between computational science, technology, and the human experience.

PI: Cecilia AlmCo-PI: Bailey Reynold

NSF$359K

A shared lab space for technologies related to the Life Sciences benefiting regional companies and encouraging interaction between academic researchers and the private sector.

Cell and Tissues Technology Laboratory

NYSESD$110K

Developing a nanopore based biosensor for high-throughput DNA sequencing.

Fabrication of Integrated Nanopore Platform for High-Throughput Sequencing

Corporate$68K

PI: Steven DayCo-PI: Vinay Abhyankar, Tom Gaborski

PI: Ke DuCo-PI: Yangming Li, Yunbo Zhang



19

Developing novel micropumps for inner ear drug delivery by determining pump parameters, functional characteristics and testing new micropumps by attenuating noise damage to the cochlea.

Enabling Microsystem Technologies for Advanced Drug Delivery

NIH$2.7M

RIT and NTID partner with the University of Rochester to train deaf/hard-of-hearing postdoctoral fellows from disciplines in biomedical sciences while promoting their growth as researchers and educators.

Rochester Partnership to Advance Research and Academic Careers in Deaf Scholars

NIH$197K

Upgrades microscope enable researchers to study in realtime with high-resolution cellular transmigration across the endothelial barrier and three-dimensional crawling through the underlying extracellular matrix.

PI: Tom Gaborski

Transparent Ultrathin Nanomembranes for Barrier Cell Models and Novel Co-Culture Systems

NIH$1.5M

PI: David BorkholderCo-PI: Denis Cormier, Martin K. Anselm

PI: Richard DoolittleCo-PI: Matthew Dye

Development and validation of ultrasound based elastography method to measure spatially resolved strain fields in mouse tendons.

PI: Michael Richards

Ultrasound elastography for non-invasive assessment of tendon healing

NIH$32K

RIT is increasing the number and quality of psychology interns who are trained to provide access to quality substance use services.

Training Clinical Psychology Interns to use Evidence Based Care Models and Tele-Behavioral Health Technology to Treat OUD and SUD in Monroe County

HRSA$1.3M

PI: Caroline EastonCo-PI: Cassandra Berbary, Cory Crane

Providing clear and definitive means of imaging prostate cancer (PCa) using magnetic resonance imaging (MRI).

High Relaxivity PSMA-Targeted Contrast Agents for MRI of Prostate Cancer

NIH$569K

PI: Hans SchmitthennerCo-PI: Irene Evans, Joseph Hornak



This project, we will evaluate the use of non-contact video recording technology to detect the presence of AF and deliver an estimation of AF burden.

PI: Gill Tsouri

Home-based videoplethysmographic detection of atrial fibrillation

NIH/UR$896K

This research will develop a new noninvasive electrical imaging system to provide an effective identification of potential ablation targets with a potential to improve the standard of care and clinical outcomes of VT ablation.

PI: Linwei Wang

Peri-procedural transmural electrophysiological imaging of scar-related ventricular tachycardia

NIH$3.1M

Identifying miRNA candidates that are associated with TLR2 signaling in human nucleus pulposus and annulus fibrosus cells by next generation sequencing, and establishing their functional role in DDD.

PI: Karin Wuertz-Kozak

Functional role of Toll-like receptor associated microRNAs in intervertebral disc pathophysiology

SNSF$257K

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NEW RESEARCH PROJECTS$5.19 MM in new awards for FY2020

NIH$2.9M

Inconspicous Daily Monitoring to Reduce Heart Failure Hospitalizations

PI: David Borkholder


Colgate PalmoliveUofR

$10K$5K

Bio-Fluids Movement in Biomemetic Microchannels

CRISPR-Cas13a Enabled Sensitive Optofluidics Platform for Zika RNA Sensing

PI: Ke DuPI: Ke Du

$6K

Preparation of Gold-DNA and quantum dot-DNA probes for photonic detection of SARS-CoV-2

PI: Ke Du

SiPhox$68K

Fabrication of Integrated Nanopore Platform for High-Throughput Sequencing

PI: Ke Du

Shenzhen Ruhan Gene Tech Co Ltd

NIH/Drexel$337K

Multifunctional VAD Technology for High-Risk Pediatric Patients

PI: Steven Day

NIH/SiMPore$79K

A Modular Platform for the Development and Analysis of Barrier Tissue Models

PI: Vinay Abhyankar

DHHS$1.3M

Training Clinical Psychology Interns to use Evidence Based Care Models and Tele-Behavioral Health Technology to Treat OUD and SUD in Monroe County

PI: Caroline Easton

$256K

Functional role of Toll-like receptor associated microRNAs in intervertebral disc pathophysiology

PI: Karin Wuertz-Kozak

Swiss National Science Foundation

23

NIH$95K

Supplement to High Relaxivity PSMA-Targeted Contrast Agents for MRI of Prostate Cancer

PI: Hans Schmitthenner

Help to dramatically reduce the cost of healthcare

Discover, invent, and produce life-changing health technologies and systems

Create new companies that will alter economic and personal health landscapes

Enable populations across the globe – both economically marginalized and geographically removed – to access healthcare that is currently unavailable to them

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OPPORTUNITIESFOR GIVING


Support of RIT’s PHT180 initiatives is the key to addressing the wide-ranging opportunities in health diagnosis and treatment. Investments in this area will make it possible for RIT to harness the unique expertise of our university: design, engineering, data analytics, computing and technology, behavioral health and healthcare systems.

The impact potential of this signature research is immeasurable. Through generous support of PHT180, RIT will be able to:

RIT’s PHT180 initiatives are helping create a world in which everyone can lead healthier lives. Support of PHT180 can help to change the largely unsustainable models of healthcare currently in place and move us more quickly toward better health, supporting new ways for healthcare providers to treat patients, improving outcomes, and creating a higher quality of life.

Harnessing RIT’s Specific Expertise Will Drive Success Support

That Changes Lives

ENDOWED PROFESSORSHIPSOutstanding faculty members are a key element to research quality. For PHT180, they bring much needed research reputations, help to establish RIT’s stature in the field, and attract the graduate degree candidates critical for research success. Demand for outstanding faculty members in technology-driven fields is fierce, and endowed professorships help to recruit top faculty to RIT.

POST-DOCTORAL FELLOWSPost-doc fellowships are the front door to a research career, and an important part of the PHT180 initiative. Postdoctoral work creates domain experts that are able to apply what they’ve learned to identify and solve new problems in healthcare technology and systems. Like faculty members, post-doctoral fellows are in high demand, competitive research support packages are an important part of bringing the best to RIT.

UNDERGRADUATE STUDENT RESEARCH

In addition to driving new knowledge, research at RIT provides experience for undergraduate students pursuing research-intensive careers and graduate school admission. RIT brings undergraduates into advanced research projects as full members of the team so they may grow as scientists and build a published research portfolio. Few universities other than RIT expose undergraduate students to this level of research work.

DIRECT RESEARCH SUPPORTPHT180 research projects have a wide impact range. Supporters have the opportunity to drive new knowledge and problem solving in areas that matter to them by funding research initiatives in specific areas. Investments in the research programs of specific PHT180 faculty can support that researcher’s achievements, or a supporter may choose to establish a research fund with defined parameters for a specific discipline or industry issue.

GRADUATE STUDENT RESEARCHGraduate students are essential to research teams in PHT180, and the research opportunities afforded them to have a tremendous impact on the overall quality of the initiative. In addition, graduate research helps to drive new knowledge and academic quality into the undergraduate programs that are connected to PHT180. A strong graduate research program, with support for affiliated research projects is critical to attracting highly-qualified master’s and Ph.D. students to RIT.

25

PHT180 Engaging faculty and students in new ways

DISCOVER SUPPORT PROMOTE26

"

"

PHT180 was my first job as a medical illustrator/ graphic designer and was a great platform for me to understand how to work more efficiently and professionally. Many of my artworks were published in research journals and as cover art, which was an exciting and unique experience for me. Getting my works noticed on social media helps me to build a stronger portfolio/ resume. It has been a very cool experience to work with students and professors from different programs at RIT. I was so inspired by an interesting research topic with a professor that I ended up using the topic for my graduate thesis.

MFA Student, Medical IllustrationWenrong He

"

"

When I began working at RIT in fall 2019, PHT180 not only helped me to create a professional website to display my research internally and externally, it has also supported me in creating outreach material for back pain patients. Furthermore, knowing little about the US funding system upon my arrival, PHT180 has guided me through the application process and has been crucial in being able to submit several grant proposals.

Professor, KGCOEKarin Wuertz-Kozak

"

"

The PHT180 team provides dedicated mentorship for my healthcare-based research. From website design and administrative support to assisting with identifying and writing grants their expertise is invaluable. My affiliation with PHT 180 helps in making interdisciplinary connections on campus and provides access to unique funding opportunities to support my scholarly agendas.

Assistant Professor, CADMary Golden

"

"

PHT180 is a great platform to elevate the research of the faculty members at RIT. The mentors and grant editor are willing to spend time helping me to polish my research proposals. PHT180 is helping faculty members to design the schematics in manuscripts and grant proposals. With this great support, some of our works at RIT have been selected as cover stories by top international journals such as ACS Sensor, ACS Infectious Diseases, ACS Applied Materials & Interfaces, and Advanced Functional Materials and are widely covered by media such as Yahoo, Science Daily, EurekAlert!, and RIT News.

Assistant Professor, KGCOEKe Du

PUBLICATIONSAccess Technology

Pariti, J., Tibdewal, V., & Oh, T. (2020). Intelligent Mobility Cane-Lessons Learned from Evaluation of Obstacle Notification System using a Haptic Approach. Case Study of the 2020 CHI Conference on Human Factors in Computing Systems, 1–8.https://doi.org/10.1145/3334480.3375217

Suresh, M., Pariti, J., & Oh, T. (2019). Dynamic Sensor Orientation Unit for the Intelligent Mobility Cane. The 21st International ACM SIGACCESS Conference on Computers and Accessibility, 548–550. https://doi.org/10.1145/3308561.3354627

Artificial Intelligence

Abdollahi, M., Ashouri, S., Abedi, M., Azadeh-Fard, N., Parnianpour, M., Khalaf, K., & Rashedi, E. (2020). Using a Motion Sensor to Categorize Nonspecific Low Back Pain Patients: A Machine Learning Approach. Sensors, 20(12), 3600. https://doi.org/10.3390/s20123600

Chen, J., Hao, H., Hong, H., & Kong, Y. (2020). RIT-18: A Novel Dataset for Compositional Group Activity Understanding. In Proceedings of the IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (pp. 362-363). https://openaccess.thecvf.com/content_CVPRW_2020/papers/w22/Chen_RIT-18_A_Novel_Dataset_for Compositional_Group_Activity_Understanding_CVPRW_2020_paper.pdf

Dhamala, J., Bajracharya, P., Arevalo, H. J., Sapp, J. L., Horácek, B. M., Wu, K. C., Trayanova, N. A., & Wang, L. (2020). Embedding high-dimensional Bayesian optimization via generative modeling: Parameter personalization of cardiac electrophysiological models. Medical Image Analysis, 62, 101670. https://doi.org/10.1016/j.media.2020.101670

Gyawali, P., Li, Z., Knight, C., Ghimire, S., Horacek, B. M., Sapp, J., & Wang, L. (2019). Improving Disentangled Representation Learning with the Beta Bernoulli Process. 2019 IEEE International Conference on Data Mining (ICDM), 1078–1083. https://doi.org/10.1109/ICDM.2019.00127

Gyawali, Prashnna Kumar, Li, Z., Ghimire, S., & Wang, L. (2019). Semi-supervised Learning by Disentangling and Self-ensembling over Stochastic Latent Space. In D. Shen, T. Liu, T. M. Peters, L. H. Staib, C. Essert, S. Zhou, P.-T. Yap, & A. Khan (Eds.), Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 (pp. 766–774). Springer International Publishing. https://doi.org/10.1007/978-3-030-32226-7_85

Gyawali, Prashnna Kumar., Horacek., B. M., Sapp., J. L., & Wang, L. (2020). Sequential Factorized Autoencoder for Localizing the Origin of Ventricular Activation From 12-Lead Electrocardiograms. IEEE Transactions on Biomedical Engineering, 67(5), 1505–1516. https://doi.org/10.1109/TBME.2019.2939138

Gyawali, Prashnna Kumar., Ghimire, S., Bajracharya, P., Li, Z., & Wang, L. (2020). Semi-supervised Medical Image Classification with Global Latent Mixing. ArXiv:2005.11217 [Cs, Eess, Stat]. http://arxiv.org/abs/2005.11217

27PHT180 Annual Report

Behavioral Health

Eiden, R. D., Godleski, S. A., Colder, C. R., Livingston, J. A., Leising, M. C., & Leonard, K. E. (2020). Early Childhood Risk and Protective Factors Predicting Resilience against Adolescent Substance Use. Adversity and Resilience Science. https://doi.org/10.1007/s42844-020-00007-5

Eiden, R., Zhao, J., Ettekal, I., Schuetze, P., Nickerson, A., Ostrov, J., Godleski, S., & Granger, D. (2020). Prenatal cocaine exposure and other substance exposure: Pathways to individual differences in stress reactivity in adolescence. 60th Annual Meeting of the Society for Birth Defects Research and Prevention. Abstract in Neurotoxicology and Teratology, 79. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252070/

Gilchrist, G., Landau, S., Radcliffe, P., McMurran, M., Feder, G., Easton, C., Parrott, S., Kirkpatrick, S., Henderson, J., Potts, L., Stephens-Lewis, D., Johnson, A., Love, B., Halliwell, G., Dheensa, S., Berbary, C., Li, J., Strang, J., & Gilchrist, E. (2020). A study protocol to assess the feasibility of conducting an evaluation trial of the ADVANCE integrated intervention to address both substance use and intimate partner abuse perpetration to men in substance use treatment. Pilot and Feasibility Studies, 6(1), 62. https://doi.org/10.1186/s40814-020-00580-7

Godleski, S. A., Eiden, R. D., Shisler, S., & Livingston, J. A. (2020). Parent socialization of emotion in a high-risk sample. Developmental Psychology, 56(3), 489–502. https://doi.org/10.1037/dev0000793

Li, K., Kong, Y., & Fu, Y. (2020). Visual Object Tracking Via Multi-Stream Deep Similarity Learning Networks. IEEE Transactions on Image Processing, 29, 3311–3320. https://doi.org/10.1109/TIP.2019.2959249

Murkute, J. V., Damania, R. J., Nair, N. R., Kotecha, N. R., Wicks, C., Phipps, R., Ptucha, R., & Papier, A. (2020). Adding uncertainty to dermatological assistance. Medical Imaging 2020: Image Processing, 11313, 113131H. https://doi.org/10.1117/12.2549769

Qi, Y., Jin, L., Li, H., Li, Y., & Liu, M. (2020). Discrete Computational Neural Dynamics Models for Solving Time-Dependent Sylvester Equations with Applications to Robotics and MIMO Systems. IEEE Transactions on Industrial Informatics, 1–1. https://doi.org/10.1109/TII.2020.2966544

Wang, Han, Hong, Y., Kong, Y., & Vaidya, J. (2020) Publishing Video Data with Indistinguishable Objects. 23rd International Conference on Extending Database Technology. In EDBT (pp. 323-334). http://cs.iit.edu/~yhong/pub/edbt20.pdf

Zang, C., Pei, M., & Kong, Y. Few-shot Human Motion Prediction via Learning Novel Motion Dynamics. International Joint Conference on Artificial Intelligence (IJCAI), 2020.https://www.ijcai.org/Proceedings/2020/0118.pdf

Zhang, Y., Tian, Y., Kong, Y., Zhong, B., & Fu, Y. (2020). Residual Dense Network for Image Restoration. IEEE Transactions on Pattern Analysis and Machine Intelligence, 1–1. https://doi.org/10.1109/TPAMI.2020.2968521'

Zheng, Z., Li, X., Barnes, J., Park, C.-H., & Jeon, M. (2019). Facial Expression Recognition for Children: Can Existing Methods Tuned for Adults Be Adopted for Children? International Conference on Human-Computer Interaction, 201–211.https://doi.org/10.1007/978-3-030-22643-5_16


Godleski, S. A., & Ostrov, J. M. (2020). Parental influences on child report of relational attribution biases during early childhood. Journal of Experimental Child Psychology, 192, 104775. https://doi.org/10.1016/j.jecp.2019.104775

Godleski, S. A., Shisler, S., Eiden, R. D., & Schuetze, P. (2020). Maternal Smoking and Psychosocial Functioning: Impact on Subsequent Breastfeeding Practices. Breastfeeding Medicine, 15(4), 246–253. https://doi.org/10.1089/bfm.2019.0148

Godleski, S., Lohse, B., & Krall, J. S. (2019). Satter Eating Competence Inventory Subscale Restructure After Confirmatory Factor Analysis. Journal of Nutrition Education and Behavior, 51(8), 1003–1010. https://doi.org/10.1016/j.jneb.2019.05.287

Grom, J. L., Crane, C., Leone, R. M., Parrott, D. J., & Eckhardt, C. (2019). Sexual Violence Perpetration Within Intimate Relationships: An I3 Model Analysis of the Effects of Sexual Violence Victimization and Psychological Flexibility. Sexual Abuse, 1079063219877176. https://doi.org/10.1177/1079063219877176

Hansen, S., & Baroody, A. J. (2019). Electronic Health Records and the Logics of Care: Complementarity and Conflict in the U.S. Healthcare System. Information Systems Research, 31(1), 57–75. https://doi.org/10.1287/isre.2019.0875

Nickerson, A. B., Shisler, S., Eiden, R. D., Ostrov, J. M., Schuetze, P., Godleski, S. A., & Delmerico, A. M. (2020). A Longitudinal Study of Gun Violence Attitudes: Role of Childhood Aggression and Exposure to Violence, and Early Adolescent Bullying Perpetration and Victimization. Journal of School Violence, 19(1), 62–76. https://doi.org/10.1080/15388220.2019.1703716

Nowalis, S. Godleski, S. A., & Schenkel, L. S., (n.d.). Attachment as a Moderator in the Relation Between Child Maltreatment and Symptoms of Depression. Retrieved June 24, 2020, https://doi.org/10.1177%2F0886260520933050

Oh, H., Lee, Y., Choi, W., & Zheng, Z. (2019). Challenges in Self-management among Older Adults with Hypertension and Diabetes. Innovation in Aging, 3(Supplement_1), S316-S317.https://doi.org/10.1093/geroni/igz038.1155

Perry, K. J., Ostrov, J. M., Shisler, S., Eiden, R. D., Nickerson, A. B., Godleski, S. A., & Schuetze, P. (2020). Pathways from Early Family Violence to Adolescent Reactive Aggression and Violence Victimization. Journal of Family Violence. https://doi.org/10.1007/s10896-019-00109-4

Shisler, S., Godleski, S., Molnar, D. S., & Eiden, R. D. (2020). Salivary Bioscience Research Related to Prenatal Adversity. In D. A. Granger & M. K. Taylor (Eds.), Salivary Bioscience: Foundations of Interdisciplinary Saliva Research and Applications (pp. 611–639). Springer International Publishing. https://doi.org/10.1007/978-3-030-35784-9_25

Stein, K. F., Trabold, N., & Connelly, K. (2019). Unhealthy weight control strategies: An outcome of body image and eating tensions in women of Mexican origin living in rural farming communities. Journal of Health Psychology, 24(9), 1293–1304. https://doi.org/10.1177/1359105317694490

Trabold, N., McMahon, J., Alsobrooks, S., Whitney, S., & Mittal, M. (2020). A systematic review of intimate partner violence interventions: State of the field and implications for practitioners. Trauma, Violence, & Abuse, 21(2), 311–325.https://doi.org/10.1177/1524838018767934

Trabold, N., Swogger, M., McMahon, J., Cerulli, C., & Poleshuck, E. (2020). A Brief Motivational Intervention to Address Intimate Partner Violence Victimization: A Pilot Study. Research on Social Work Practice, 1049731519900652.https://doi.org/10.1177/1049731519900652

Zheng, Z., Nie, G., Swanson, A., Weitlauf, A., Warren, Z., & Sarkar, N. (2020). A Randomized Controlled Trial of an Intelligent Robotic Response to Joint Attention Intervention System. Journal of Autism and Developmental Disorders, 1–13.https://doi.org/10.1007/s10803-020-04388-5

29

https://doi.org/10.1093/geroni/igz038.1155

Ahmed, A., Joshi, I. M., Larson, S., Gholizadeh, S., Forouzandeh, F., Borkholder, D. A., Gaborski, T. R., & Abhyankar, V. V. (2020). Microengineered three-dimensional collagen fiber landscapes with independently tunable anisotropy and directionality. BioRxiv, 2020.06.12.148346. https://doi.org/10.1101/2020.06.12.148346

Allahyari, Z., Casillo, S., Perry, S., Peredo, A., & Gaborski, T "Disrupted Surfaces Reduce Nuclear YAP Localization through Diminished Cell Spreading in ADSCs" Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019

Admed, A., Mylott, J., Lee, N., Larson, S., Gaborski, T., & Abjuamlar. V.. "TMicrofluidic Shear Based Approach to Fabricate Physically Distinct Tissue Interfaces" Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019

Allahyari, Z., Gholizadeh, S., Chung, H. H., Delgadillo, L. F., & Gaborski, T. R. (2020). Micropatterned Poly(ethylene glycol) Islands Disrupt Endothelial Cell–Substrate Interactions Differently from Microporous Membranes. ACS Biomaterials Science & Engineering, 6(2), 959–968. https://doi.org/10.1021/acsbiomaterials.9b01584

Cambria, E., Brunner, S., Heusser, S., Fisch, P., Hitzl, W., Ferguson, S. J., & Wuertz-Kozak, K. (2020). Cell-laden agarose-collagen composite hydrogels for mechanotransduction studies. Frontiers in Bioengineering and Biotechnology, 8. https://dx.doi.org/10.3389%2Ffbioe.2020.00346

Cazzanelli, P., & Wuertz-Kozak, K. (2020). MicroRNAs in Intervertebral Disc Degeneration, Apoptosis, Inflammation, and Mechanobiology. International Journal of Molecular Sciences, 21(10), 3601. https://doi.org/10.3390/ijms21103601

Chen, X., Falzon, L., Zhang, J., Zhang, X., Wang, R.-Q., & Du, K. (2019). Experimental and theoretical study on the microparticle trapping and release in a deformable nano-sieve channel. Nanotechnology, 31(5), 05LT01. https://doi.org/10.1088/1361-6528/ab2279

Chen, X., Miller, A., Cao, S., Gan, Y., Zhang, J., He, Q., Wang, R.-Q., Yong, X., Qin, P., Lapizco-Encinas, B. H., & Du, K. (2020). Rapid Escherichia coli Trapping and Retrieval from Bodily Fluids via a Three-Dimensional Bead-Stacked Nanodevice. ACS Applied Materials & Interfaces, 12(7), 7888–7896. https://doi.org/10.1021/acsami.9b19311

Davoudi, M., Shokouhyan, S. M., Abedi, M., Meftahi, N., Rahimi, A., Rashedi, E., Hoviattalab, M., Narimani, R., Parnianpour, M., & Khalaf, K. (2020). A Practical Sensor-Based Methodology for the Quantitative Assessment and Classification of Chronic Non Specific Low Back Patients (NSLBP) in Clinical Settings. Sensors, 20(10), 2902. https://doi.org/10.3390/s20102902

Dehghani, M., Gulvin, S. M., Flax, J., & Gaborski, T. R. (2020). Systematic Evaluation of PKH Labelling on Extracellular Vesicle Size by Nanoparticle Tracking Analysis. Scientific Reports, 10(1), 9533. https://doi.org/10.1038/s41598-020-66434-7

Dehghani, M., Lucas, K., Flax, J., McGrath, J., & Gaborski, T. (2019). Tangential Flow Microfluidics for the Capture and Release of Nanoparticles and Extracellular Vesicles on Conventional and Ultrathin Membranes. Advanced Materials Technologies, 4(11), 1900539. https://doi.org/10.1002/admt.201900539

Forouzandeh, F., Zhu, X., Alfadhel, A., Ding, B., Walton, J. P., Cormier, D., Frisina, R. D., & Borkholder, D. A. (2019). A nanoliter resolution implantable micropump for murine inner ear drug delivery. Journal of Controlled Release, 298, 27–37. https://doi.org/10.1016/j.jconrel.2019.01.032

Forouzandeh F., Abhyankar, V., Borkholder, D.A. "A Miniature Zero-power Plug-and-play Pump for Perfusion Applications." Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019

Biomedical micro/nano technologies


Gholizadeh, S., Allahyari, Z., Carter, R., Delgadillo, L. F., Blaquiere, M., Nouguier-Morin, F., Marchi, N., & Gaborski, T. R. (2020). Robust and Gradient Thickness Porous Membranes for In Vitro Modeling of Physiological Barriers. BioRxiv, 2020.05.07.083188. https://doi.org/10.1101/2020.05.07.083188

Hass, K. N., Bao, M., He, Q., Park, M., Qin, P., & Du, K. (2020). Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection (IMPACT) System for Rapid Viral DNA Sensing. BioRxiv, 2020.03.17.994137. https://doi.org/10.1101/2020.03.17.994137

He, Q., Bao, M., Hass, K., Lin, W., Qin, P., & Du, K. (2019). Perspective of Molecular Diagnosis in Healthcare: From Barcode to Pattern Recognition. Diagnostics, 9(3), 75. https://doi.org/10.3390/diagnostics9030075

He, Q., Yu, D., Bao, M., Korensky, G., Chen, J., Shin, M., Kim, J., Park, M., Qin, P., & Du, K. (2020). High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection us-ing CRISPR-Cas12a and fluorescence based point-of-care system. Biosensors and Bioelectronics, 154, 112068. https://doi.org/10.1016/j.bios.2020.112068

Hill, K., Walker, S. N., Salminen, A., Chung, H. L., Li, X., Ezzat, B., Miller, J. J., DesOrmeaux, J.-P. S., Zhang, J., Hayden, A., Burgin, T., Piraino, L., May, M. N., Gaborski, T. R., Roussie, J. A., Taylor, J., DiVincenti, L., Shestopalov, A. A., McGrath, J. L., & Johnson, D. G. (2020). Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis. Advanced Healthcare Materials, 9(4), 1900750. https://doi.org/10.1002/adhm.201900750

Inyang, E., Abhyankar, V., Chen, B., & Cho, M. (2020). Modulation of in vitro Brain Endothelium by Mechanical Trauma: Structural and Functional Restoration by Poloxamer 188. Scientific Reports, 10(1), 3054. https://doi.org/10.1038/s41598-020-59888-2

Khire, T. S., Salminen, A. T., Swamy, H., Lucas, K. S., McCloskey, M. C., Ajalik, R. E., Chung, H. H., Gaborski, T. R., Waugh, R. E., Glading, A. J., & McGrath, J. L. (2020). Microvascular Mimetics for the Study of Leukocyte–Endothelial Interactions. Cellular and Molecular Bioengineering, 13(2), 125–139. https://doi.org/10.1007/s12195-020-00611-6

Korensky, G., Chen, X., Bao, M., Miller, A., Lapizco-Encinas, B., Park, M., & Du, K. (2020). Single Chlamydomonas reinhardi (C. reinhardtii) cell separation from bacterial cells and auto-fluorescence tracking with a nano-sieve device. BioRxiv, 2020.02.14.949867. https://doi.org/10.1101/2020.02.14.949867

Krupkova, O., Greutert, H., Boos, N., Lemcke, J., Liebscher, T., & Wuertz-Kozak, K. (2020). Expression and activity of hyaluronidases HYAL-1, HYAL-2 and HYAL-3 in the human intervertebral disc. European Spine Journal, 29(3), 605–615. https://doi.org/10.1007/s00586-019-06227-3

Loepfe, M., Duss, A., Zafeiropoulou, K.-A., Björgvinsdóttir, O., D’Este, M., Eglin, D., Fortunato, G., Klasen, J., Ferguson, S. J., Wuertz-Kozak, K., & Krupkova, O. (2019). Electrospray-Based Microencapsulation of Epigallocatechin 3-Gallate for Local Delivery into the Intervertebral Disc. Pharmaceutics, 11(9), 435. https://doi.org/10.3390/pharmaceutics11090435

Mehren, C., Wuertz-Kozak, K., Sauer, D., Hitzl, W., Pehlivanoglu, T., & Heider, F. (2019). Implant Design and the Anchoring Mechanism Influence the Incidence of Heterotopic Ossification in Cervical Total Disc Replacement at 2-year Follow-up. Spine, 44(21), 1471–1480. https://doi.org/10.1097/BRS.0000000000003098

Forouzandeh, Farzad, Zhu, Xiaoxia, Ahamed, Nuzhet N., Walton, Joseph P., Frisina, Robert D., Borkholder, David A., "An Implantable, Refillable, And Scalable Microsystem For Chronic Murine Inner Ear Drug Delivery." Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2020).

Forouzandeh, F., Ahamed, N. N., Hsu, M. C., Walton, J. P., Frisina, R. D., & Borkholder, D. A. (2020). A 3D-Printed Modular Microreservoir for Drug Delivery. Micromachines, 11(7), 648.https://doi.org/10.3390/mi11070648

Miller, J. J., Carter, J. A., Hill, K., DesOrmeaux, J.-P. S., Carter, R. N., Gaborski, T. R., Roussie, J. A., McGrath, J. L., & Johnson, D. G. (2020). Free Standing, Large-Area Silicon Nitride Membranes for High Toxin Clearance in Blood Surrogate for Small-Format Hemodialysis. Membranes, 10(6), 119. https://doi.org/10.3390/membranes10060119

31

Mireles, M., Soule, C. W., Delgadillo, L. F., & Gaborski, T. R. (2019). Nanopatterned Thermoresponsive Functionalization of Substrates via Nanosphere Lithography. BioRxiv, 796268. https://doi.org/10.1101/796268

Mireles, M., Soule, C., Delgadillo, L., &, Gaborski, T,. "TSurface-Specific Thermoresponsive Coating of Membranes" Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019

Mireles, M., W. Soule, C., Dehghani, M., & R. Gaborski, T. (2020). Use of nanosphere self-assembly to pattern nanoporous membranes for the study of extracellular vesicles. Nanoscale Advances. https://doi.org/10.1039/D0NA00142B

Moudgalya, Sanketh S., Cahill, Nathan D., Borkholder, David A., "Deep Volumetric Segmentation of Murine Cochlear Compartments from Micro-Computed Tomography Images." 42nd Annual International Conferences of the IEEE Engineering in Medicine and Biology Society (EMBC 2020), Montreal, Canada, July (2020).

Moudgalya, S. S., Wilson, K., Zhu, X., Budzevich, M. M., Walton, J. P., Cahill, N. D., Frisina, R. D., & Borkholder, D. A. (2019). Cochlear pharmacokinetics—Micro-computed tomography and learning-prediction modeling for transport parameter determination. Hearing Research, 380, 46–59. https://doi.org/10.1016/j.heares.2019.05.009

Moudgalya, Sanketh S., Zhu, Xiaoxia, Budzevich, Mikalai M., Walton, Joseph P., Cahill, Nathan D., Frisina, Robert D., Borkholder, David A., "Cochlear Pharmacokinetics – Impact of 3D Segmentation using Convolutional Neural Networks.” Association for Research in Otolaryngology (ARO) Midwinter meeting, February (2020).

Piazza, N., Dehghani, M., Gaborski, T. R., & Wuertz-Kozak, K. (2020). Therapeutic Potential of Extracellular Vesicles in Degenerative Diseases of the Intervertebral Disc. Frontiers in Bioengineering and Biotechnology, 8, 311. https://doi.org/10.3389/fbioe.2020.00311

Qin, P., Park, M., Alfson, K. J., Tamhankar, M., Carrion, R., Patterson, J. L., Griffiths, A., He, Q., Yildiz, A., Mathies, R., & Du, K. (2019). Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a. ACS Sensors, 4(4), 1048–1054. https://doi.org/10.1021/acssensors.9b00239

Rode, R. P., Chung, H. H., Miller, H. N., Gaborski, T. R., & Moghaddam, S. (2020). Bilayer graphene oxide membranes for a wearable hemodialyzer. BioRxiv, 2020.05.26.116863. https://doi.org/10.1101/2020.05.26.116863

Sadowska, A., Hitzl, W., Karol, A., Jaszczuk, P., Cherif, H., Haglund, L., Hausmann, O. N., & Wuertz-Kozak, K. (2019). Differential regulation of TRP channel gene and protein expression by intervertebral disc degeneration and back pain. Scientific Reports, 9(1), 18889. https://doi.org/10.1038/s41598-019-55212-9

Salminen, A, Tithof,J, McCloskey, M, Ishiman, Y, Waugh, R, Gaborski, T, & McGrath, J. "The Role of Endothelial Cell Apicobasal Polarity in Sepsis Associated Neutrophil Dysfunction" Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019

Wippert, P.-M., Block, A., Mansuy, I. M., Peters, E. M., Rose, M., Rapp, M. A., Huppertz, A., & Wuertz-Kozak, K. (2019). Alterations in bone homeostasis and microstructure related to depression and allostatic load. Psychotherapy and Psychosomatics, 88(6), 383–385. https://doi.org/10.1159/000503640

Schmid, B., Hausmann, O., Hitzl, W., Achermann, Y., & Wuertz-Kozak, K. (2020). The Role of Cutibacterium acnes in Intervertebral Disc Inflammation. Biomedicines, 8(7), 186.https://doi.org/10.3390/biomedicines8070186

Karvekar, S., Abdollahi, M., & Rashedi, E. (2019). A Data-Driven Model to Identify Fatigue Level Based on the Motion Data from a Smartphone. 2019 IEEE Western New York Image and Signal Processing Workshop (WNYISPW), 1–5. https://doi.org/10.1109/WNYIPW.2019.8923100

Williams, M., Lee, N., Mylott, J., Mazzola, N., Ahmed, A., & Abhyankar, V. "A Low-Cost, Rapidly Integrated Debubbler (RID) Module for Microfluidic Cell Culture Applications." Biomedical Engineering Society (BMES) annual meeting, Philadelphia, PA, Oct. 2019


33

Das, Moumita. (n.d.). APS -APS March Meeting 2020—Event—Time varying mechanical response of cytoskeletal networks. Bulletin of the American Physical Society, Volume 65, Number 1. Retrieved June 24, 2020, from http://meetings.aps.org/Meeting/MAR20/Session/J20.2

Farhadi, L., Ricketts, S. N., Rust, M. J., Das, M., Robertson-Anderson, R. M., & Ross, J. L. (2020). Actin and microtubule crosslinkers tune mobility and control co-localization in a composite cytoskeletal network. Soft Matter. https://doi.org/10.1039/C9SM02400J

Farhadi, Leila, Rust, Michael, Das, Moumita, Robertson-Anderson, Rae, & Ross, Jennifer. (n.d.-b). APS -APS March Meeting 2020—Event—Actin crosslinking controls mobility, microtubule crosslinkers control co-localization in a composite cytoskeletal network. Bulletin of the American Physical Society, Volume 65, Number 1. Retrieved July 9, 2020, from https://meetings.aps.org/Meeting/MAR20/Session/L20.6

Francis, M. L., Ricketts, S. N., Farhadi, L., Rust, M. J., Das, M., Ross, J. L., & Robertson-Anderson, R. M. (2019). Non-monotonic dependence of stiffness on actin crosslinking in cytoskeleton composites. Soft Matter, 15(44), 9056–9065. https://doi.org/10.1039/C9SM01550G

Gurmessa, B., Francis, M., Rust, M. J., Das, M., Ross, J. L., & Robertson-Anderson, R. M. (2019). Counterion crossbridges enable robust multiscale elasticity in actin networks. Physical Review Research, 1(1), 013016. https://doi.org/10.1103/PhysRevResearch.1.013016

Kornick, K., Bogner, B., Sutter, L., & Das, M. (2019). Population Dynamics of Mitochondria in Cells: A Minimal Mathematical Model. Frontiers in Physics, 7. https://doi.org/10.3389/fphy.2019.00146

Lee, G., Rust, M. J., Das, M., McGorty, R. J., Ross, J. L., & Robertson-Anderson, R. M. (2020). Myosin-driven actin-microtubule networks exhibit self-organized contractile dynamics. BioRxiv, 2020.06.11.146662. https://doi.org/10.1101/2020.06.11.146662

Lee, G., Rust, M. J., Das, M., Ross, J. L., & Anderson, R. (2020). Microrheology of Active Actin-microtubule Networks. Biophysical Journal, 118(3), 125a. https://doi.org/10.1016/j.bpj.2019.11.816

Lwin, Pancy, Franklin, Scott, Thurston, George, Ross, David, & Das, Moumita. (n.d.). APS -APS March Meeting 2020 - Event - Mechanical response of the vitreous gel in our eyes: Results from an inhomogeneous two-fluid model. Bulletin of the American Physical Society, Volume 65, Number 1. Retrieved June 24, 2020, from http://meetings.aps.org/Meeting/MAR20/Session/L26.4

Melcher, Lauren, Rennert, Elisabeth, Ross, Jennifer, Rust, Michael, Robertson-Anderson, Rae, & Das, Moumita. (n.d.). APS -APS March Meeting 2020—Event—Computational study of autonomous mechanical oscillations in a colloidal network crosslinked via clock proteins. Bulletin of the American Physical Society, Volume 65, Number 1. Retrieved June 24, 2020, from http://meetings.aps.org/Meeting/MAR20/Session/R25.13

Ricketts, S. N., Francis, M. L., Farhadi, L., Rust, M. J., Das, M., Ross, J. L., & Robertson-Anderson, R. M. (2019). Varying crosslinking motifs drive the mesoscale mechanics of actin-microtubule composites. Scientific Reports, 9(1), 12831. https://doi.org/10.1038/s41598-019-49236-4

Ricketts, S. N., Khanal, P., Rust, M. J., Das, M., Ross, J. L., & Robertson-Anderson, R. M. (2020). Triggering Salt-Induced Contraction of Cytoskeletal Networks with Microfluidics. Biophysical Journal, 118(3), 350a. https://doi.org/10.1016/j.bpj.2019.11.2021

Ross, J. L., Ricketts, S. N., Farhadi, L., Das, M., Rust, M., & Anderson, R. (2020). Actin Controls the Dynamics and Microtubule Crosslinkers Tune Co-localization in Crosslinked Composite Actin-microtubule Networks. Biophysical Journal, 118(3), 125a. https://doi.org/10.1016/j.bpj.2019.11.819

Biophysics

Cardiovascular Health

Dhamala, J., Ghimire, S., Sapp, J. L., Horáček, B. M., & Wang, L. (2019). Bayesian Optimization on Large Graphs via a Graph Convolutional Generative Model: Application in Cardiac Model Personalization. MICCAI 2019. Springer International Publishing https://doi.org/10.1007/978-3-030-32245-8_51

Dhamala, J., Bajracharya, P., Arevalo, H. J., Sapp, J. L., Horácek, B. M., Wu, K. C., Trayanova, N. A., & Wang, L. (2020). Embedding high-dimensional Bayesian optimization via generative modeling: Parameter personalization of cardiac electrophysiological models. Medical Image Analysis, 62, 101670. https://doi.org/10.1016/j.media.2020.101670

Gyawali, Prashnna Kumar, Horacek, B. M., Sapp, J. L., & Wang, L. (2020). Sequential Factorized Autoencoder for Localizing the Origin of Ventricular Activation From 12-Lead Electrocardiograms. IEEE Transactions on Biomedical Engineering, 67(5), 1505–1516. https://doi.org/10.1109/TBME.2019.2939138

Sapp John L., Zhou Shijie, & Wang Linwei. (2020). Mapping Ventricular Tachycardia With Electrocardiographic Imaging. Circulation: Arrhythmia and Electrophysiology, 13(2), e008255. https://doi.org/10.1161/CIRCEP.120.008255

Xie, S., Wang, L., Zhang, H., & Liu, H. (2019). Non-invasive reconstruction of dynamic myocardial transmembrane potential with graph-based total variation constraints. Healthcare Technology Letters, 6(6), 181–186. https://doi.org/10.1049/htl.2019.0065

Healthcare Systems and Bioinformatics

Azadeh-Fard, N., Megahed, F. M., & Pakdil, F. (2019). Variations of length of stay: A case study using control charts in the CRISP-DM framework. International Journal of Six Sigma and Competitive Advantage, 11(2–3), 204–225. https://doi.org/10.1504/IJSSCA.2019.101418

Pakdil, F., Azadeh-Fard, N., & Esatoglu, A. E. (2019). Monitoring length of stay through control charts: A comparative study of diabetic patients. Hospital Practice, 47(4), 196–202. https://doi.org/10.1080/21548331.2019.1664883

Pehlivanoglu, T., Wuertz-Kozak, K., Heider, F., Sauer, D., Wanke-Jellinek, L., Mayer, M., & Mehren, C. (2019). Clinical and Radiographic Outcome of Patients With Cervical Spondylotic Myelopathy Undergoing Total Disc Replacement. Spine, 44(20), 1403–1411. https://doi.org/10.1097/BRS.0000000000003079

Zikri, Y. K. B., Helguera, M., Cahill, N. D., Shrier, D., & Linte, C. A. (2019). Toward an Affine Feature-Based Registration Method for Ground Glass Lung Nodule Tracking. In J. M. R. S. Tavares & R. M. Natal Jorge (Eds.), VipIMAGE 2019 (pp. 247–256). Springer International Publishing. https://doi.org/10.1007/978-3-030-32040-9_26


Anto-Ocrah, M., Maxwell, N., Cushman, J., Acheampong, E., Kodam, R.-S., Homan, C., & Li, T. (2020). Public knowledge and attitudes towards bystander cardiopulmonary resuscitation (CPR) in Ghana, West Africa. International Journal of Emergency Medicine, 13(1), 29. https://doi.org/10.1186/s12245-020-00286-w

Liu, T., & Homan, C. M. (2019). Twitter Job/Employment Corpus: A Dataset of Job-Related Discourse Built with Humans in the Loop. ArXiv:1901.10619 [Cs]. http://arxiv.org/abs/1901.10619

Saraf, M., Roberts, T., Ptucha, R., Homan, C., & Alm, C. O. (2019). Multimodal Anticipated versus Actual Perceptual Reactions. Adjunct of the 2019 International Conference on Multimodal Interaction, 1–5. https://doi.org/10.1145/3351529.3360663

Social and Human Computing

Choi, W., Wang, S., Lee, Y., Oh, H., & Zheng, Z. (2020). A systematic review of mobile health technologies to support self-management of concurrent diabetes and hypertension. Journal of the American Medical Informatics Association, 27(6), 939–945.https://doi.org/10.1093/jamia/ocaa029

Forouzandeh, F., Ahamed, N. N., Hsu, M. C., Walton, J. P., Frisina, R. D., & Borkholder, D. A. (2020). A 3D-Printed Modular Microreservoir for Drug Delivery. Micromachines, 11(7), 648.https://doi.org/10.3390/mi11070648

Rode, R. P., Chung, H. H., Miller, H. N., Gaborski, T. R., & Moghaddam, S. (2020). Bilayer graphene oxide membranes for a wearable hemodialyzer. BioRxiv, 2020.05.26.116863. https://doi.org/10.1101/2020.05.26.116863

Sullivan, C., DeBartolo, E., & Lamkin-Kennard, K. (2020). Method and system for monitoring terrain and gait and predicting upcoming terrain (United States Patent No. US10524699B2). https://patents.google.com/patent/US10524699B2/en?patents=false

Mobile Health

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