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PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

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Page 1: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

PDT IN DERMATOLOGYRolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

Page 2: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

PDT IN DERMATOLOGY•First use in this speciality in the early 1900• surface illumination• variety of indications (cancer, infection)

Page 3: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

PDT IN DERMATOLOGY• registered drugs since the late 90ies• 5-ALA (solution, gel, patch) (for AK)• 5-ALA methyl ester (ointment) for AK, init. SCC, nod. & superf. BCC

• no restrictions for illumination (lasers, LED, lamps, sunlight)

• excellent data• high clearance rates• favorable cosmetical results

Page 4: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

Page 5: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

Page 6: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

passed

Page 7: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

WHY ISN‘T PDT A KILLER APP?

• light / drug combination – procedure – learning

curve

• side effects esp. pain

• reimbursement issues

passed

passed

can this ever be solved?

Page 8: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

EMERGING & NEW INDICATIONS

• „classical“ NMSC-PDT

Page 9: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

GROWING INCIDENCE OF NON-MELANOMA SKIN CANCER

© DermatologyWorld 3-15

Page 10: PDT IN DERMATOLOGY Rolf-Markus Szeimies M.D. Ph.D. Recklinghausen, Germany

EMERGING & NEW INDICATIONS

• „classical“ NMSC-PDT

• PDT and aesthetic medicine

• combinatoric approaches

• PDT and microbioma/colonization

• eczema, psoriasis & pilosebaceous disorders