8
Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen, Taija M Kiviharju, Päivi M Ojala, David Meek, Marikki Laiho Cancer Cell Volume 5, Issue 5, Pages 465-475 (May 2004) DOI: 10.1016/S1535-6108(04)00110-2

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Embed Size (px)

Citation preview

Page 1: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation 

Sari Kurki, Karita Peltonen, Leena Latonen, Taija M Kiviharju, Päivi M Ojala, David Meek, Marikki Laiho 

Cancer Cell Volume 5, Issue 5, Pages 465-475 (May 2004)

DOI: 10.1016/S1535-6108(04)00110-2

Page 2: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 1

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 3: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 2

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 4: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 3

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 5: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 4

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 6: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 5

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 7: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 6

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)

Page 8: Nucleolar protein NPM interacts with HDM2 and protects tumor suppressor protein p53 from HDM2-mediated degradation Sari Kurki, Karita Peltonen, Leena Latonen,

Figure 7

Cancer Cell 2004 5, 465-475DOI: (10.1016/S1535-6108(04)00110-2)