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This continuing medical education activity is jointly provided by the NCOA and the Southern Regional Area Health Education Center
2015 Annual MeetingSpine/Basic Science/Education/Foot & Ankle/Trauma Sunday, October 11
October 9-11, 2015 • Kiawah Island Golf Resort Kiawah Island, South Carolina
North Carolina Orthopaedic Association
9/24/2015
1
THE EFFECT OF COMPUTER-
ASSISTED SURGERY TRAINING
IN THE PLACEMENT OF
ILIOSACRAL SCREWS
Elizabeth W. Hubbard, MD
NCOA October 11, 2015
Funding
OREF
Piedmont Orthopedic Society
DUMC Department of Orthopaedic Surgery
Surgical Skills Acquisition
Classic Education:
“See one, do one, teach one…”
The changing healthcare system
80 hour workweek
Reimbursement based on outcomes
The Dilemma—creating competent surgeons when
1. Trainees have less hands-on training
2. Need to teach skills in a way that is safe for patients
Computer Navigation Assisted Training
Goften et al JBJS 2007
Acetabular cup position
Computer navigation trained group:
Better accuracy
Better precision throughout training
Nousianen et al JOT 2013
Guidewire placement for femoral neck fractures
Computer navigation trained group:
Faster
Fewer attempts
No evidence of dependence on computer navigation
Goal of Study
Determine the effect of computer navigation
assisted training on learning a complex surgical skill
Overall Structure
1. Pre-test
Instructional video
All participants place S1 and S2 guidewires using
fluoroscopy
2. Randomization (Post-test)
Repeat instructional video
Expert instruction provided during guidewire placement
21 subjects: fluoroscopy; 20 subjects: computer navigation
3. Retention test—4 weeks after pre-test
4. Transfer test—4 weeks after pre-test
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Methods
41 Subjects
Surgical trainees
Senior medical students
40 completed full study (97.5% follow-up)
Data Analyzed
Total time to wire placement
Total fluoroscopy time used
Attempts at wire placement
Perforation
Overall rate
Grade of perforation (Hinsche et al CORR 2002, Zwingmann et al CORR 2009)
Set-Up
Based off a design created by Riehl
& Widmaier J Surg Ed 2011.
Fluoroscopy Computer Navigation
BrainLab Trauma (BrainLab,
Westchester, IL)
Computer Navigation (Cont.)
Set-up based off a design created by
Riehl & Widmaier J Surg Ed 2011.
BrainLab Trauma (BrainLab,
Westchester IL)
Computer Navigation (Cont.)
9/24/2015
3
Time to Wire Placement
Time to Wire
Placement
Fluoroscopy Time
Fluoroscopy Time
(min)
Perforation Grade: SI Guidewires
Perforation Grade:
S1 Guidewires
Perforation Grade: S2 Guidewires
Perforation Grade:
S2 Guidewires
Discussion
Trends towards improved accuracy regardless of training tool
Computer Navigation
Performed faster, even when using fluoroscopy
Less radiation exposure
Trend towards more accurate S1 placement
Retention and transfer test results
Lasting memory of motor skills
Subjects did not seem to develop a dependency on computer navigation
Limitations
Simulated environment
Does not account for individual patient factors that
affect surgery (body habitus, etc)
Technical issues with pelvi
Variation in fluoroscopic images between pelvi
Design of some sawbones interfered with wire
placement
Subject knowledge/skill level
Variation between medical students and surgical
trainees
9/24/2015
4
Conclusions
Computer navigation is a potential tool for teaching
complex surgical tasks
Efficient
Safe
Less radiation exposure
Performed in a controlled environment rather than on a
patient in the OR
Results suggest that trainees can transfer skills
No evidence of dependence on navigation
Thank you
Co-Authors:
Erika Templeton, MD
William C. Eward, DVM, MD
Cindy L. Green, PhD
Markku T. Nousiainen, MS, Med, MD, FRCS(C)
Robert D. Zura, MD
North Carolina Orthopaedic Association
References
1. Gofton W, Dubrowski A, Tabloie F, Backstein D: The effect of computer navigation on trainee learning of surgical skills. The Journal of bone and joint surgery American volume 2007;89:2819-2827.
2. Nousiainen MT, Omoto D, Zingg P, Weil YA, Mardam-Bey SW, Eward WC: Training Femoral Neck Screw Insertion Skills to Surgical Trainees: Computer-Assisted Surgery Versus Conventional Fluoroscopic Technique. Journal of orthopaedic trauma 2012.
3. Hinsche AF, Giannoudis PV, Smith RM: Fluoroscopy-based multiplanarimage guidance for insertion of sacroiliac screws. Clinical orthopaedics and related research 2002:135-144.
4. Zwingmann J, Konrad G, Kotter E, Sudkamp NP, Oberst M: Computer-navigated iliosacral screw insertion reduces malposition rate and radiation exposure. Clinical orthopaedics and related research 2009;467:1833-1838.
5. Riehl J, Widmaier J: A simulator model for sacroiliac screw placement. Journal of Surgical Education 2011;xx:1-4.
9/24/2015
1
A NOVEL LOCAL CANCELLOUS
AUTOGRAFT SOURCE FOR ANTERIOR
CERVICAL DISCECTOMY AND FUSION: A TECHNIQUE DESCRIPTION AND COMPARATIVE STUDY
Conor O’Neill1,2, Zakk Walterscheid1,2, Dr. Caleb Behrend1,2, Dr. Jonathan Carmouche1,2
1Virginia Tech Carilion School of Medicine2Carilion Clinic Orthopaedics-Musculoskeletal Education and Research Center
DISCLOSURES
» Conor O’Neill: None
» Zakkary Walterscheid: None
» Caleb Behrend: None
» Jonathan Carmouche:
» Member, Exhibits Committee, AAOS
» Member, Education Committee, Scoliosis Research Society
INDICATIONS FOR ACDF HISTORICAL PERSPECTIVE
Smith GW, Robinson RA. The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion. J Bone Joint Surg Am. 1958;40:607–624.
ILIAC CREST BONE GRAFT
» Donor Site Morbidity reported as high as 49%
Peelle, Michael. "A Novel Source of Cancellous Autograft for ACDF Surgery: The Manubrium." J Spinal Disord Tech 20.1 (Feb 2007): 36-41. Print.
Banwart, J. C., M. A. Asher and R. S. Hassanein (1995). "Iliac crest bone graft harvest donor site morbidity. A statistical evaluation." Spine (Phila Pa 1976) 20(9): 1055-1060.
ALTERNATIVE GRAFTS
» Alternative graft materials
» Allograft
» Demineralized Bone matrix
» Mineralized Bone matrix
» Xenograft
» Synthetic Bone Graft
» Ceramics
» Hydroxyapatite
» Bioactive Materials
» Bone Morphogenic Protein
» Bone Marrow Aspirate
Anderson, DG and Albert, TJ. “Bone grafting, implants, and plating options for anterior cervical fusion.” Orthop Clin North Am (2002) 33:317-328. Print.
Chau, Anthony and Mobbs, Ralph. “Bone graft substitutes in anterior cervical discectomy and fusion.” Eur Spine J (2009) 18:449-464. Print.
» Alternative graft Sites
» Manubrium
» Clavicle
» Rib
» Patella
9/24/2015
2
META-ANALYSIS FUSION RATES
» Range of Autograft Fusion Rate 90-100%
» Range of Allograft fusion ranges from:
» 32-100%
» Meta-Analysis Allograft Fusion Rate 78%» Floyd, Timothy. “A meta-analysis of autograft versus allograft in
anterior cervical fusion.” Eur. Spine J (2000) 9: 398-403.
Peelle, Michael. "A Novel Source of Cancellous Autograft for ACDF Surgery: The Manubrium." J Spinal Disord Tech 20.1 (Feb 2007): 36-41. Print.
Floyd, Timothy. “A meta-analysis of autograft versus allograft in anterior cervical fusion.” Eur Spine J (2000) 9: 398-403. Print.
» Graft Materials
» Alternative Graft Sites
NOVEL GRAFT SITE
9/24/2015
3
RESULTS
Pre-Op
Post-Op
0
1
2
3
4
5
6
7
8
9
10
Average Neck VAS Score
Pre-Op
Post-Op
0
1
2
3
4
5
6
7
8
9
10
Average Arm VAS Score
RESULTS
95100
0
10
20
30
40
50
60
70
80
90
100
ICBG Adjacent Vertebra
Percent Fusion following ACDF
*Fusion based upon x-ray and resolution of clinical symptoms
RESULTS
49
00
10
20
30
40
50
60
70
80
90
100
ICBG Adjacent Vertebra
Percent Reported Iliac Crest Morbidity
Banwart, J. C., M. A. Asher and R. S. Hassanein (1995). "Iliac crest bone graft harvest donor site morbidity. A statistical evaluation." Spine (Phila Pa 1976) 20(9): 1055-1060.
RESULTS
Complications Percentage
Infection 0%
Fracture 0%
Implant Subsidence 0%
Pseudoarthroses 0%
Revision Operation 0%
CONCLUSIONS
» The present study demonstrates:
» Similar rates of reduction of neck and arm pain in the published literature
» Safety and Efficacy of New Technique
» Maintenance of high fusion rate characteristic of autologous bone graft
» Technique avoids morbidity associated with second surgical site
LIMITATIONS
» Pilot study
» Small Sample Size
» Short follow-up
» Average follow-up = 10.79 months
» Fusion based upon x-ray and resolution of clinical symptoms
9/24/2015
4
REFERENCES» An, H. S., J. M. Simpson, J. M. Glover and J. Stephany (1995). "Comparison between allograft plus demineralized bone matrix versus autograft in anterior
cervical fusion. A prospective multicenter study." Spine (Phila Pa 1976) 20(20): 2211-2216.
» Anderson, DG and Albert, TJ. “Bone grafting, implants, and plating options for anterior cervical fusion.” Orthop Clin North Am (2002) 33:317-328. Print.
» Banwart, J. C., M. A. Asher and R. S. Hassanein (1995). "Iliac crest bone graft harvest donor site morbidity. A statistical evaluation." Spine (Phila Pa 1976)
20(9): 1055-1060.
» Berven, S., B. K. Tay, F. S. Kleinstueck and D. S. Bradford (2001). "Clinical applications of bone graft substitutes in spine surgery: consideration of mineralized and demineralized preparations and growth factor supplementation." Eur Spine J 10 Suppl 2: S169-177.
» Chau, A. M. and R. J. Mobbs (2009). "Bone graft substitutes in anterior cervical discectomy and fusion." Eur Spine J 18(4): 449-464.
» Cloward, R. B. (1988). "The anterior surgical approach to the cervical spine: the Cloward Procedure: past, present, and future. The presidential guest
lecture, Cervical Spine Research Society." Spine (Phila Pa 1976) 13(7): 823-827.
» Floyd, T. and D. Ohnmeiss (2000). "A meta-analysis of autograft versus allograft in anterior cervical fusion." Eur Spine J 9(5): 398-403.
» Iwasaki, K., T. Ikedo, H. Hashikata and H. Toda (2014). "Autologous clavicle bone graft for anterior cervical discectomy and fusion with titanium interbodycage." J Neurosurg Spine 21(5): 761-768.
» Jacobs, W. C., P. G. Anderson, J. Limbeek, P. C. Willems and P. Pavlov (2004). "Single or double-level anterior interbody fusion techniques for cervical
degenerative disc disease." Cochrane Database Syst Rev(4): CD004958.
» Lied, B., P. A. Roenning, J. Sundseth and E. Helseth (2010). "Anterior cervical discectomy with fusion in patients with cervical disc degeneration: a prospective outcome study of 258 patients (181 fused with autologous bone graft and 77 fused with a PEEK cage)." BMC Surg 10: 10.
» Lu, D. C., L. M. Tumialan and D. Chou (2013). "Multilevel anterior cervical discectomy and fusion with and without rhBMP-2: a comparison of dysphagia rates and outcomes in 150 patients." J Neurosurg Spine 18(1): 43-49.
» Matz, P. G., L. T. Holly, M. W. Groff, E. J. Vresilovic, P. A. Anderson, R. F. Heary, M. G. Kaiser, P. V. Mummaneni, T. C. Ryken, T. F. Choudhri, D. K. Resnick, S. Joint Section on Disorders of the, S. Peripheral Nerves of the American Association of Neurological and S. Congress of Neurological (2009). "Indications for anterior cervical decompression for the treatment of cervical degenerative radiculopathy." J Neurosurg Spine 11(2): 174-182.
» Peelle, M. W., B. A. Rawlins and P. Frelinghuysen (2007). "A novel source of cancellous autograft for ACDF surgery: the manubrium." J Spinal Disord Tech
20(1): 36-41.
» Pollock, R., I. Alcelik, C. Bhatia, G. Chuter, K. Lingutla, C. Budithi and M. Krishna (2008). "Donor site morbidity following iliac crest bone harvesting for cervical fusion: a comparison between minimally invasive and open techniques." Eur Spine J 17(6): 845-852.
» Radhakrishnan, K., W. J. Litchy, W. M. O'Fallon and L. T. Kurland (1994). "Epidemiology of cervical radiculopathy. A population-based study from
Rochester, Minnesota, 1976 through 1990." Brain 117 ( Pt 2): 325-335.
» Schnee CL, Freese A, Weil RJ, Marcotte PJ (1997) Analysis of harvest morbidity and radiographic outcome using autograft for anterior cervical fusion. Spine 22:2222–2227.
» Smith, G. W. and R. A. Robinson (1958). "The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody
fusion." J Bone Joint Surg Am 40-A(3): 607-624.
Figure 1
Figure 3 Figure 4
Figure 2
Pre-Op
Post-Op
0
2
4
6
8
10
Average Neck VAS Score
Pre-Op
Post-Op
0
2
4
6
8
10
Average Arm VAS Score
9/24/2015
1
Impact of Bone MorphogenicProtein-7 (BMP-7) on Cell Migration
on the MeniscusVictor Taylor II, Ph.D.Ian Hutchinson, M.D.Kerry Danelson, Ph.D.Cristin Ferguson, M.D.
Introduction
• Osteoarthritis is the most frequent cause of disability among adults in the United States
• Damage or loss of meniscus tissue is associated with degeneration of the joint
Normal
OA
Meniscus Repair
• Interluekin-1 is a pro-inflammatory cytokine
– Inhibits repair processes
• BMP-7 is an anabolic growth factor
– Supports matrix synthesis in articular cartilage even in the presence of IL-1
• Limited research involving BMP-7 and meniscus repair
Objective of the Study
• Examine the effects of BMP-7 on cell migration in an in vitro meniscus repair model
• Evaluating the potential of BMP-7 to augment meniscus repair
Method
• Tissue: Porcine knees from local abattoir– Female, >/= 3 years old– 6mm meniscus explants created with a
biopsy punch• Collagen type 1 scaffold sandwiched
between meniscus explants in a cloning tube to create a one-dimensional growth factor diffusion gradient– Control– Treated scaffold
• BMP-7• PDGF-AB• IL-1a• BMP-7+ IL-1a
• Incubation for 28 days in Dulbecco Modified Eagle Medium with 10% fetal bovine serum– In untreated scaffolds- meniscus cells
migrate toward media as source of nutrition (away from scaffold Adapted from: Can platelet-rich plasma enhance anterior cruciate
ligament and meniscal repair? J Knee Surg. 2015 Feb; 28(1): 19-28.Hutchinson ID, Rodeo SA, Perrone GS, and Murray MM.
Method
• 4',6-diamidino-2-phenylindole (DAPI) histology Stain
• Cell Count between 3 zones– Inner– Middle– Outer
• Five groups– Control (n=7)– BMP-7 (n=8)– PDGF-AB (n=2)– IL-1 alpha (n=4)– BMP-7 + IL-1 (n=4)
Outer
Middle
Inner
Inner
Middle
Outer
Media
9/24/2015
2
Results
BMP-7
• Inner zone- 26%
• Middle zone- 40%
• Outer zone- 35%
PDGF• Inner zone- 23%• Middle zone- 37%• Outer zone- 40%
Control• Inner zone- 26%• Middle zone- 29%• Outer zone- 45%
Results
IL-1 alpha
• Inner zone- 23%
• Middle zone- 32%
• Outer zone- 45%
BMP-7 + IL-1 alpha
• Inner zone- 17%
• Middle zone- 25%
• Outer zone- 58%
Discussion
• Preliminary results suggest BMP-7 may induce cell migration in meniscus tissue
• Impact of local BMP-7 on proteoglycan production will be analyzed
• Additional cell culture based studies will compare local proliferation versus migration effects
Acknowledgements
• Cristin Ferguson M.D. (mentor)
• Kerry Danelson, Ph.D.
• Ian Hutchinson, M.D.
• Institutional Research and Academic Career Development Awards (IRACDA) (NIH/NIGMS K12 PAR-13-290)
Questions
9/24/2015
1
Whole Body Vibration Increases Cartilage Thicknessand Cancellous Bone Strength, but Not Femoral
Neck Strength or Bone MineralDensity.
William Runge, MS1, Laurence Dahners, MD1, Denis Marcellin-Little, DEDV2, Ola Harryson, PhD2, David Ruppert,
MS1,2, Paul Weinhold, PhD1
1University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
2North Carolina State University, Raleigh, NC, USA.
Introduction
• Whole body vibration (WBV) has been proposed as a non-pharmaceutical intervention for osteoporosis
• WBV provides mechanical stimulation that may drive bone growth
• Previous studies on WBV have shown modest changes in bone mineral density1, but few have assessed changes in bone strength or cartilage properties
• Optimal parameters for whole body vibration are unknown2
Hypothesis
• Short duration exposure to WBV can produce measurable changes in– Bone mineral density
– Cancellous bone strength
– Femur neck strength
– Medial epicondyle cartilage thickness
• Studying a range of treatment amplitudes might identify optimal parameters for the application of this therapy
Methods
• 80 adult Sprague-Dawley rats, divided into 5 groups of 16 animals each
• Each group was assigned to 0, 0.15, 0.3, 0.6, or 1.2g of sinusoidal vibration at 45 Hz, using an electromagnetic shaker
• 15 minutes of vibration therapy per day, for 6 weeks• Animals sacrificed at end of 6 weeks, and femurs isolated• Mechanical tests conducted at constant displacement rate on a load
cell as described 3
• Bone mineral density measured on Hologic QDR Disovery A DXA machine, using regions of interested modeled after those used in vitro4
• Cartilage thickness measured based on histologic sections of a subset of animals, using an ImageJ processing routine that averages the thickness of the cartilage across the weight-bearing area
Methods Results: Bone mineral density
No significant difference in bone mineral density between individual groups or when vibrated animals are lumped and compared to control
9/24/2015
2
Results: Mechanical strenth
• 70% increase in cancellous bone strength in the vibrated animals versus the control
• No change in femur neck strength between groups
Results: Cartilage thickness
• Vibrated animals had significantly thicker (30%) cartilage on the medial condyle compared to the control
Conclusion
• WBV over a 6-week treatment period causes a large improvement (70% increase) in strength of the distal femoral cancellous bone
• WBV also significantly increases the cartilage thickness at the medial epicondyle of the femur
• WBV does not alter bone mineral density on this treatment timeline
• WBV also does not alter femur neck strength on this treatment timeline
• No clearly optimal amplitude for vibration therapy
References
1. Verschueren et al. (2004). Journal of Bone and Mineral Research, 19(3), 352-359.
2. Wysocki et al. (2011). Annals of Internal Medicine, 155(10), 680-686, W206-13.
3. Ke et al. (1998). Bone, 23(3), 249-255.
4. Sievanen et al. (1994). Journal of Bone
and Mineral Research, 9(4), 473-478.
9/24/2015
1
A Prospective Evaluation of Three Serum Biomarkers in Hip Arthroscopy Patients and Matched Controls
Austin V. Stone MD, PhD* | Elizabeth A Howse MD‡
Christopher Stem* | Allston J. Stubbs MD, MBA*
North Carolina Orthopaedic Association 2015 Annual Meeting, Kiawah Island, SC
*Department of Orthopaedic SurgeryWake Forest School of Medicine, Winston-Salem, NC USA‡Department of Emergency Medicine, Kaiser Permanente, San Francisco, CA USA
DisclosuresAllston J. Stubbs MD, MBAFinancial relationships with the following companies:
• Consultant: Smith & Nephew
• Stock: Johnson & Johnson
• Research Support: Bauerfeind
• Department Support: Smith & Nephew Endoscopy, Depuy, Mitek
• Boards/Committees: AOSSM, ISHA, AANA
Austin V. Stone MD, PhD• Research Support: Smith & Nephew
Dr. Howse and Mr. Stem have nothing to disclose.
This study funded by the Department of Orthopaedic Surgery, Wake Forest School of Medicine.
Introduction
• Unknown predicative value of serum biomarkers
• FAI and hip dysplasia are implicated in articular cartilage destruction
• Vascular cell adhesion molecule-1 (VCAM-1) predictive of progressing to hip or knee replacement surgery
• IL-6 and cartilage oligomeric matrix protein (COMP)
Hip Arthroscopy Surgical Candidates
(n=20)
Age and Gender Matched Controls
(n=10)
Serum Biomarkers VCAM, COMP, IL-6
Serum Biomarkers VCAM, COMP, IL-6
Hip Arthroscopy
Serum Biomarkers
The serum biomarkers increased together.
R = 0.579; p=0.007
9/24/2015
2
Age, BMI, VCAM-1 and COMP were significant predictors of the Vail functional Hip Score (p=0.012). Most significant predictors were VCAM-1 level (p=0.016) and the BMI (p=0.011).
Vail Hip Score
significant correlations
modified Harris hip score (R = 0.671; p<0.001)
SF-36 (R = 0.702; p=0.007)
NHS (R = 0.880; p<0.001)
MHOT total score (R=0.765; p<0.001)
Discussion
VCAM-1, IL-6, and COMP were not different between pre-arthritic hip pain patients and matched controls.
Elevated pre-arthritic markers may predict patient functional outcomes reported in the Vail Hip Score.
Acknowledgements
Wake Forest School of Medicine Hypertension and Vascular CenterDr. Bridget Brosnihan
Hypertension Core Laboratory
Funding provided by a Wake Forest School of Medicine Medical Student Research Grant and the Department of Orthopaedic Surgery.
9/24/2015
1
The July Effect:
Does Time During the Academic Year and
Level of Resident Involvement Affect
Complication Rates in Lower Extremity
Orthopaedic Trauma?
Aaron J. Casp MD1, Brendan M. Patterson, MD2,
Benjamin R. Parker MD2, Joshua N. Tennant MD2
1University of Virginia Department of Orthopaedic Surgery2University of North Carolina Department of Orthopaedics
Introduction
• Surgical complications are becoming more
important in the current regulatory
landscape
• The “July effect”: is it real?
Edelstein et al., Impact of Resident Involvement on Orthopaedic Surgery Outcomes. JBJS. 2014 96(15):e131.
Schoenfeld et al., The Impact of Resident Involvement on Post-Operative Morbidity and Mortality Following Orthopaedic
Procedures. Arch Orthop Trauma Surg 2013 133(11):1483-91.
• July effect in orthopaedic trauma has not
been previously investigated
• Association between level
of resident and complication
rates is unknown
Introduction
Edelstein et al., Impact of Resident Involvement on Orthopaedic Surgery Outcomes. JBJS. 2014 96(15):e131.
Schoenfeld et al., The Impact of Resident Involvement on Post-Operative Morbidity and Mortality Following Orthopaedic
Procedures. Arch Orthop Trauma Surg 2013 133(11):1483-91.
Methods
• Identified top 2 ACGME resident case
requirements for lower extremity fractures:» Operative fixation of hip fractures
» Operative fixation of femoral fractures, or tibial shaft
fractures
• Utilized American College of Surgeons
National Quality Improvement Program
(NSQIP) database, 2005-2012
Methods – Cases Analyzed
Lower Extremity Trauma Procedures Analyzed
Procedure Description CPT code
Percutaneous Hip Pinning 27235
Hip hemiarthroplasty 27236
Sliding hip screw for hip fracture 27244
Intramedullary nail fixation of hip fracture 27245
Intramedullary nail fixation of femoral shaft fracture 27506
Plate & screw fixation of femoral shaft fracture 27507
Plate & screw fixation of tibial shaft fracture 27758
Intramedullary nail fixation of tibial shaft fracture 27759
Methods - Analysis
• Compared complication rates in the first
academic quarter with that of the rest of
the year
• Analysis was completed for all residents,
then separately for junior residents
(PGY1,2 or 3) and senior residents
(PGY4,5 or 6)
9/24/2015
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Methods – Outcome Variables Serious Adverse Events
Any Adverse Events Results – Serious Adverse Events
†P-value= 0.0324
Results – Any Adverse Events
†P-value= 0.0444
‡P-value= 0.0238
Conclusions
• There is no evidence of a July effect in lower
extremity orthopaedic trauma surgery» This holds true for all residents, and separately for junior and
senior residents
» In agreement with previous literature on elective orthopaedic
surgery
• Senior residents have a higher Any Adverse
Event rate than junior residents in the first half
of the year» More supervision at the beginning of the year?
Bohl et al., “The ‘July Effect’ in Primary Total Hip and Knee Arthroplasty.” J Arthroplasty. 2014 29(7):1332-8
Bohl et al., “‘July Effect’ in Elective Spine Surgery.” Spine 2014. 39(7):603-11.
.
9/24/2015
3
Thank You References• Bohl et al., The ‘July Effect’ in Primary Total Hip and Knee Arthroplasty. J
Arthroplasty. 2014 29(7):1332-8.
• Bohl et al., ‘July Effect’ in Elective Spine Surgery. Spine 2014. 39(7):603-11.
• Edelstein et al., Impact of Resident Involvement on Orthopaedic Surgery
Outcomes. JBJS 2014. 96(15):e131.
• Pugely et al., The Effect of Resident Participation on Short-term Outcomes
After Orthopaedic Surgery. CORR 2014 472(7):2290-2300
• Schoenfeld et al., The Impact of Resident Involvement on Post-Operative
Morbidity and Mortality Following Orthopaedic Procedures. Arch Orthop
Trauma Surg 2013. 133(11):1483-91.
9/24/2015
1
Gabriella Ode, MD; Bryan Loeffler, MD; R. Chris Chadderdon, MD; Nikkole Haines, MD; Brian Scannell, MD;
Joshua Patt, MD, MPH; Glenn Gaston, MD
Background
Wrist Arthroscopy
• Challenging discipline to gain proficiency
• Limited exposure during residency
Background
Computer Simulated Arthroscopy Training
• Shown to improve user proficiency in knee arthroscopy.
• No wrist arthroscopy simulation models are readily available.
• No studies exist which evaluate the translatability of joint-specific arthroscopy skills to other anatomic joints.
Purpose
• To investigate whether simulated knee arthroscopy training translates to improved wrist arthroscopy proficiency.
MethodsSubjects
• 26 orthopaedic residents (April 2014 – Aug 2014) participated in arthroscopy simulation training program over a 4-week period.
– 21 PGY1 to PGY5 from the 20132014 academic year
– 5 matriculating PGY1 from the 20142015 year (PGY0).
Methods• Preparation Materials
– 5 minute Demo video of test landmarks performed by experienced Hand Surgeon
– Wrist Anatomy Review
– 2 Book chapter excerpts on wrist arthroscopy• Hand Surgery, 1st Ed. “Principles of Portal Placement and Anatomy”
• Green’s Operative Hand Surgery. “Chapter 18 – Wrist Arthroscopy: Anatomy and Diagnosis”
– JAAOS Review on Wrist Arthroscopy• “ Wrist Arthroscopy: Principles and Clinical Applications – Gupta et al”
– VuMedi.com Videos
• “Wrist Arthroscopy Portal Placement”
• “Arthroscopic Anatomy of the Wrist”
9/24/2015
2
MethodsBaseline Assessment
• Subjects video-recorded performing cadaveric diagnostic wrist arthroscopy
• 10 minutes allotted to ID 23 anatomic landmarks in 4 portals
• Arthroscopy footage synchronized with video of the trainees’ de-identified hands.
MethodsTest Objectives
Test Objectives (10 min. allotted)
3, 4 portal:
Scaphoid
Scaphoid facet
RSC ligament
Long RL
ligament
RSL ligament
Short RL
ligament
Interfossal
ridge
Lunate
Lunate facet
TFCC
SL ligament
6, R portal:
Ulnar
extrinsic
ligaments
TFCC
LT ligament
Mid-carpal
ulnar portal:
Capitate
Capitohamate
joint
LT ligament
Lunate
SL ligament
Arcuate
ligament
Mid-carpal
radial
portal:
Capitate
SL
ligament
LT ligament
MethodsIntervention
Subjects given 4 weeks to complete a diagnostic knee arthroscopy module on the ArthroSim knee simulator (Touch of Life Technologies, Aurora, CO). ArthroSim:
high fidelity, virtual reality simulator that features haptic feedback and real-time manipulation of a leg to simulate the movements of the leg when performing knee arthroscopy.
Endorsed by AAOS for knee simulation training
Completion = Achieve at least 80% proficiency in all modules for a simulated diagnostic knee scope.
Methods
Post-Simulation Assessment (@ 4 weeks)
Repeat of video-recorded diagnostic arthroscopy procedure on same cadaver wrist
Pre- and Post-Simulation performance on wrist arthroscopy performance reviewed and graded in double-blinded fashion by 3 experienced hand surgeons.
ASSET (Arthroscopic Surgery Skill Evaluation Tool)
• Likert Scale:
– 1= Novice; 3 = Competent; 5 = Expert
– Range of 9-41 pts
• Domains:
– Safety (1-5pt)
– Field of View (1-5pt)
– Camera Dexterity (1-5pt)
– Instrument Dexterity (1-5pt)
– Bimanual Dexterity (1-5 pt)
– Flow of Procedure (1-5pt)
– Quality of Procedure (1-5pt)
– Autonomy (1-3pt)
– Added Complexity of Procedure (1-3pt)
Objective Data
• Composite Score
– ASSET Global Rating Scale
– Task Completion Score
– Completion Time Bonus• Max time allotted (600s) – Time spent (s) ÷ 10
Total Score = ASSET + Completion Score + Time Score
100% 75%-99% 50%-74% 25%-49% >25%
20pts 15pts 10pts 5 pts 0 pts
9/24/2015
3
Subjective Data
• Resident Pre- and Post-Simulation Surveys
– Demographics
• Age, Sex, Program year, handedness, video game experience
– Estimated Arthroscopy Case Experience
– Subjective level of comfort and proficiency
Results - ASSET
• Inter-rater Reliability
– Good to Excellent Inter-rater Reliability between graders
• Construct Validity
– Wrist arthroscopy competency no correlation with previous wrist or knee arthroscopy experience or program level
Results –Subjective OutcomesFound ArthroSim Helpful in Improving Wrist Arthroscopy Skills (Y/N)
Program Year Yes/No % Yes
All Residents
PGY-5
PGY-4
PGY-3
PGY-2
PGY-1
PGY-0
17/9
2/1
2/2
1/4
3/2
4/0
5/0
65.4%
33.3%
50%
20%
60%
100%
100%
Perceived Change in Level of Comfort Performing Wrist Arthroscopy
Improved 17 68.2%
No Change 8 27.3%
Worse 1 4.5%
Percieved Areas of Improvement in Technical Wrist Arthroscopy Skills
Camera Dexterity 16 61.5%
Flow of Procedure 13 50%
Bimanual Dexterity 9 34.6%
Instrument Dexterity 6 23.1%
Quality of Procedure 5 19.2%
None 5 19.2%
Safety 3 11.5%
65% of residents found ArthroSim intervention helpful and perceived improved wrist arthroscopy proficiency.
Greatest improvements in Camera dexterity and flow of procedure
More junior residents (PGY found the intervention helpful than senior residents
PY0 PY0 PY0 PY0 PY0 PY1 PY1 PY1 PY1 PY2 PY2 PY2 PY2 PY2 PY3 PY3 PY3 PY3 PY3 PY4 PY4 PY4 PY4 PY5 PY5 PY5Han
dSurg.
Pre-Sim 32 35 72 25 12 54 83 22 21 30 53 39 40 12 26 36 53 54 23 36 47 47 40 20 66 43 90
Post-Sim 23 40 63 40 10 43 79 20 33 32 29 25 44 26 52 41 61 50 36 50 35 62 45 17 62 36 90
0
10
20
30
40
50
60
70
80
90
100
Co
mp
osi
te S
core
Pre-Sim Post-Sim
PGY-0 PGY-1 PGY-2 PGY-3 PGY-4 PGY-5HandSurg
Results - Pre vs Post-Sim Scores
Results
• ArthroSim training no significant change for all subjects
– ASSET scores
– task completion rates
– completion times
– overall score
Discussion
– Prospective study with standardized intervention and double-blinded assessment
– ASSET validated objective measure of assessment
– Small sample size Likely affected significance
– Minimal clinically significant difference for ASSET remains unknown
– Effect of increasing duration of knee simulation training unknown
9/24/2015
4
Summary
• The ASSET Global Rating Scale is a reliable assessment tool for evaluating proficiency in wrist arthroscopy however, construct validity not demonstrated.
• A majority of subjects reported subjective improvement with greatest value among junior residents.
• Knee arthroscopy simulation training did not objectively improve wrist arthroscopy competency among orthopaedic residents.
• Wristspecific arthroscopy training exercises are needed to aid in wrist arthroscopy competency among orthopaedic residents.
References
• Gomoll AH, O’Toole RV, Czarnecki J, Warner JJP. Surgical experience correlates with performance on a virtual reality simulator for shoulder arthroscopy. Am J Sports Med. 2007;35:883-888.
• Arthroscopy Association of North America: Suggested guidelines for the practice of arthroscopic surgery. Arthroscopy 2011;5:A28.
• Hall MP, Kaplan KM, Gorczynski CT, Zuckerman JD, Rosen JE. Assessment of arthroscopic training in U.S. orthopaedic surgery residency programs: A resident self-assessment. Bull NYU Hosp Jt Dis. 2010;68:5-10.
• Modi CS, Morris G, Mukherjee R. Computer-simulation training for knee and shoulder arthroscopy. Arthroscopy. 2010;26:832-840
• Koehler RJ, Nicandri GT. Using the arthroscopic surgery skill evaluation tool as a pass-fail examination. J Bone Joint Surg Am. 2013 Dec 4;95(23):e1871-6. doi: 10.2106/JBJS.M.00340. PubMed PMID: 24306710.
• Koehler RJ, Amsdell S, Arendt EA, Bisson LJ, Braman JP, Butler A, Cosgarea AJ, Harner CD, Garrett WE, Olson T, Warme WJ, Nicandri GT. The Arthroscopic Surgical Skill Evaluation Tool (ASSET). Am J Sports Med. 2013 Jun;41(6):1229-37. PubMed PMID: 23548808.
• Coughlin RP, Pauyo R, Sutton JC, Bergeron SG. A Validated Orthopaedic Surgical Simulation Model for Training and Evaluation of Basic Arthroscopic Skills. J Bone Joint Surg Am. 2015 Sept;97:1465-71
9/24/2015
1
Differences between Various Methods of
Measuring the Size of Posterior Malleolus
Fracture Fragments
D. Landry Jarvis, MD PGY2
Wake Forest Orthopaedic Resident
October 11, 2015
Wake Forest Baptist Medical Center
Authors
Sharon N. Babcock, MD; Alejandro Marquez-Lara
MD; Kerry Danelson, PhD; Robert Morgan, BS;
Eben A. Carroll, MD; Anna N. Miller, MD;
Primary Faculty Contributor: Jason J. Halvorson, MD
2
Wake Forest Baptist Medical Center
Disclosures
I have no financial relationship with or interest in
any commercial entity that may have a direct
interest in the subject matter of this presentation.
3 Wake Forest Baptist Medical Center
BackgroundTrimalleolar Ankle Fractures
Wake Forest Baptist Medical Center
Trimalleolar Fractures• Poorer functional outcomes when compared to ankle fractures that do
not involve posterior malleolus1-3
• Generally accepted to fix posterior malleolus fragments with greater
than 25% of articular surface13
• Poor reliability and accuracy in measuring percentage involvement7-10
5 Wake Forest Baptist Medical Center
Measuring the Posterior Fragment
6
Linear Measurements
Lateral Radiograph Midpoint Sagittal CT Scan
9/24/2015
2
Wake Forest Baptist Medical Center
Measuring the Posterior Fragment
7
Surface Area Measurements
2 Dimensional 3 DimensionalAxial CT Scan Mimics Software
Wake Forest Baptist Medical Center
Study DesignRetrospective Chart Review
Wake Forest Baptist Medical Center
Subjects
• Single Hospital, Level 1 Trauma Center
• Trimalleolar fractures that underwent ORIF during a
5 year period (2009-2014)
• Inclusion criteria: Skeletally mature, acceptable
lateral radiograph, preoperative CT Scan with a
located ankle, 3 month follow up.
• 270 charts reviewed; 91 patients included
9 Wake Forest Baptist Medical Center
Methods
• A single resident obtained measurements from all 91
subjects using the 4 previously described methods
• Primary Aims: Accuracy of different measurement
methods, correlation to posterior fragment fixation
• Secondary Outcome Measures: Range of motion,
complications, pain, length of stay
• Statistical analysis using ANOVA, Pearson
correlation, and logistical regression models
10
Wake Forest Baptist Medical Center
ResultsDemographics and Outcomes
Wake Forest Baptist Medical Center
Demographics
12
52.9
Years Old
72.5%
Female
36.3%
Smokers
73.6%
Twisting injury Mechanism
91.2%
Closed
85.7%
Medial Malleolus Fracture
9/24/2015
3
Wake Forest Baptist Medical Center
Variations in Measurements by Method
13
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7
% F
ragm
ent
(Lat
eral
x-r
ay)
% Fragment (Sagittal CT)
r = 0.485, p < 0.001
Wake Forest Baptist Medical Center
Variations in Measurements by Method
14
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7
% F
ragm
en
t (S
agit
talC
T)
2D CT % Fragment Surface Area
r = 0.567, p <0.001
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0 0.1 0.2 0.3 0.4 0.5 0.6 0.7
% F
ragm
en
t (L
ate
ral
x-ra
y)
2D CT % Fragment Surface Area
r = 0.554, p < 0.001
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0 0.2 0.4 0.6 0.8
% F
ragm
en
t(S
agit
talC
T)
3D-Reconstruction % Fragment Surface Area
r = 0.476, p < 0.001
0
0.1
0.2
0.3
0.4
0.5
0.6
0.7
0 0.2 0.4 0.6 0.8
% F
ragm
en
t(L
ate
ral
x-ra
y)
3D-Reconstruction % Fragment Surface Area
r = 0.545, p < 0.001
Wake Forest Baptist Medical Center
Lateral X-Ray
• 23.9% ± 11.1
Sagittal CT
• 26.4% ± 8.6
2D Surface Area
• 16.4% ± 11.8
3D Surface Area
• 28.7% ± 12.0
Variations in Measurements by Method
15
P = 0.02 P < 0.001P < 0.001
Wake Forest Baptist Medical Center
Posterior Fragment Fixation
16
53.8% treated without fixation(n = 49)
46.2% treated with fixation(n = 42)
Wake Forest Baptist Medical Center
Size of Fragment by Decision to Fix
17
Lateral X-Ray
22.5%
25.8%
0.139
Sagittal CT
24.0%
29.1%
0.008
2D Surface Area
16.4%
17.5%
0.651
3D Surface Area
28.3%
29.5%
0.614
Not Fixed
Fixed
P-value
Wake Forest Baptist Medical Center
DiscussionAnalysis and Conclusions
9/24/2015
4
Wake Forest Baptist Medical Center
Conclusions
• Although there was a moderate positive correlation between
the 4 methods of measurement, there was a great variability
in the estimated posterior fragment size.
• Axial CT scans underestimated size, where as 3D
Reconstruction imaging overestimated size.
• There was no significant difference in the outcomes of
fractures treated with or without posterior fragment fixation.
• Sagittal CT scan and lateral radiographs appear to both be
sufficiently appropriate for measuring posterior malleolus
fragments
19 Wake Forest Baptist Medical Center
References
20
• 1.Heim UF. Trimalleolar fractures: late results after fixation of the posterior fragment. Orthopedics 1989;12:1053-1059.
• 2.Wei SY, Okereke E, Winiarsky R, Lotke PA. Nonoperatively treated displaced bimalleolar and trimalleolar fractures: a 20-year follow-
up. Foot & ankle international 1999;20:404-407.
• 3.De Vries J, Struijs PA, Raaymakers EL, Marti RK. Long-term results of the Weber operation for chronic ankle instability: 37 patients
followed for 20-30 years. Acta orthopaedica 2005;76:891-898.
• 4.Gardner MJ, Brodsky A, Briggs SM, Nielson JH, Lorich DG. Fixation of posterior malleolar fractures provides greater syndesmotic
stability. Clinical orthopaedics and related research 2006;447:165-171.
• 5.Miller AN, Carroll EA, Parker RJ, Helfet DL, Lorich DG. Posterior malleolar stabilization of syndesmotic injuries is equivalent to screw
fixation. Clinical orthopaedics and related research 2010;468:1129-1135.
• 6.van den Bekerom MP, Haverkamp D, Kloen P. Biomechanical and clinical evaluation of posterior malleolar fractures. A systematic
review of the literature. The Journal of trauma 2009;66:279-284.
• 7.Buchler L, Tannast M, Bonel HM, Weber M. Reliability of radiologic assessment of the fracture anatomy at the posterior tibial plafond
in malleolar fractures. Journal of orthopaedic trauma 2009;23:208-212.
• 8.Wang L, Shi ZM, Zhang CQ, Zeng BF. Trimalleolar fracture with involvement of the entire posterior plafond. Foot & ankle
international 2011;32:774-781.
• 9.Irwin TA, Lien J, Kadakia AR. Posterior malleolus fracture. The Journal of the American Academy of Orthopaedic Surgeons
2013;21:32-40.
• 10.Gonzalez O, Fleming JJ, Meyr AJ. Radiographic assessment of posterior malleolar ankle fractures. The Journal of foot and ankle
surgery : official publication of the American College of Foot and Ankle Surgeons 2015;54:365-369.
• 11.Haraguchi N, Haruyama H, Toga H, Kato F. Pathoanatomy of posterior malleolar fractures of the ankle. The Journal of bone and
joint surgery American volume 2006;88:1085-1092.
• 12.Mangnus L, Meijer D, Stufkens SA, et al. Posterior Malleolar Fracture Patterns. Journal of orthopaedic trauma 2015.
• 13.McDaniel WJ, Wilson FC. Trimalleolar fractures of the ankle. An end result study. Clinical orthopaedics and related research
1977:37-45.
• 14.Mingo-Robinet J, Lopez-Duran L, Galeote JE, Martinez-Cervell C. Ankle fractures with posterior malleolar fragment: management
and results. The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
2011;50:141-145.
• 15.Bartonicek J, Rammelt S, Kostlivy K, Vanecek V, Klika D, Tresl I. Anatomy and classification of the posterior tibial fragment in ankle
fractures. Arch Orthop Trauma Surg 2015;135:505-516.
• 16.Black EM, Antoci V, Lee JT, et al. Role of preoperative computed tomography scans in operative planning for malleolar ankle
fractures. Foot & ankle international 2013;34:697-704.
• 17.Ferries JS, DeCoster TA, Firoozbakhsh KK, Garcia JF, Miller RA. Plain radiographic interpretation in trimalleolar ankle fractures
poorly assesses posterior fragment size. Journal of orthopaedic trauma 1994;8:328-331.
• 18.Purnell GJ, Glass ER, Altman DT, Sciulli RL, Muffly MT, Altman GT. Results of a computed tomography protocol evaluating distal
third tibial shaft fractures to assess noncontiguous malleolar fractures. The Journal of trauma 2011;71:163-168.
Wake Forest Baptist Medical Center
Thank You
9/25/2015
1
Major Perioperative Complications Are
Higher In Ankle Fusion Than Total Ankle
Arthroplasty: Results of a Matched
Cohort Study
Susan Odum, PhDBryce Van Doren, MPA, MPH
Robert B. Anderson, MDW. Hodges Davis, MD
Introduction
• Ankle fusion is the traditional surgical treatment for end stage arthritis
• Total ankle arthroplasty (TAA) utilization is
increasing as technique and implants improve
• Evidence suggests that clinical outcomes are superior with TAA
• Little is known of the perioperative complication rate
Purpose
To compare the national rates of
perioperative (in-hospital) complications
between patients undergoing
ankle fusion and total ankle arthroplasty
Methods
• 2002-2012 releases of the Nationwide Inpatient Samples were analyzed.
• 3,638 TAA patients and 15,053 ankle fusion patients were identified using ICD-9-CM procedure codes (81.11 and 81.56, respectively).
• ICD-9-CM diagnosis codes used to identify patients that experienced major or minor perioperative complications.
Minor Complications ICD-9 Codes Conditions
Circulatory
451.11, 451.19, 451.81,
451.89, 453.40-453.42,
453.50-453.52, 453.6,
453.9
phlebitis, thrombophlebitis, venous embolism
thrombosis
Respiratory 518.5 pulmonary insufficiency
Other systems, unclassified
997.1, 997.2, 997.39, 997.4,
997.5, 997.91, 997.99
cardiac, periphera; vascular, digestive, urinary,
respiratory
Other medical care, unclassified
999.2, 999.39, 999.5, 999.6,
999.7, 999.88-999.9
vascular; serum, injection, infusion and
transfusion reactions
Other procedure, unclassified
998.11-98.13, 998.59,
998.81, 998.83, 998.89
wound, hematoma, seroma, infection,
emphysema
Major Complications ICD-9 Codes Conditions
Circulatory and Respiratory
427.5, 415.11, 415.12,
415.19
cardiac arrest, iatrgenic pulmonary embolism
and infarction; septic pulmonary embolism
Specific Procedure
996.40-996.49, 996.66,
996.67, 996.77-996.79
internal orthopedic device, implant or graft;
including infection
Other systems, unclassified
997.00-997.02, 997.09,
997.31, 997.79
nervous system, central nervous system,
iatrogenic cerebrovascular infarction or
hemorrhage, vascular, respiratory
Other medical care, unclassified 999.4 anaphylactic shock
Other procedure, unclassified
998.0, 998.30, 998.32,
998.4, 998.51, 998.7
postoperative shock, foreign body left, surgical
wound disruption, infected seroma
Methods
• Statistical matching
identified 3,424 exact
matches of ankle fusion
and TAA patients
matched on
– age
– gender
– race
– hospital type
– geographical region
– # comorbidities
– diabetes status
• Perioperative
complications (including in-
hospital mortality) were
compared between
procedures using
– bivariate statistics
(unadjusted rates)
– multivariate logistic
regression (adjusted
rates)
9/25/2015
2
Results: Mortality
Mortality
Yes No P value
Ankle Fusion 6 (0.2%) 3418 (99.8%)
0.53Total Ankle 4 (0.1%) 3420 (99.9%)
After controlling for patient demographics and case-mix, ankle fusion patients were 50% more likely to die during hospitalization than TAA patients (OR: 1.50, 95% CI: 0.42-5.35).
Results: Major Complications
Major Complications
Yes No P-value
Ankle Fusion 482 (14%) 2,942 (86%)
.01Total Ankle 220 (6%) 3,204 (94%)
After adjusting for patient demographics and case mix, ankle fusion patients were 2.43 times more likely to experience major complications (OR: 2.42, 95% CI 2.05-2.88).
Results: Minor Complications
Minor Complications
Yes No P-value
Ankle Fusion 133 (4%) 3,291 (96%)0.17
Total Ankle 156 (5%) 3,268 (95%)
After adjusting for patient demographics and case-mix, ankle fusion patients were 15.7% less likely to experience a minor complication (OR: 0.84, 95% CI 0.66-1.07).
Conclusion
• Compared to a matched cohort of TAA patients, ankle fusion patients have
significantly higher risk of a major perioperativecomplications.
• The risk of a minor perioperative complication and mortality are similar between the groups
• These findings suggest that TAA may be a safer surgery than ankle fusion.
Thank you
9/24/2015
1
Duke University Medical Center
Predictors of Failure for Delayed Surgical Management of Closed Ankle Fracture-
dislocations
Andrew P. Matson, MD, Cynthia L. Green, PhD, Shepard R. Hurwitz and Robert D. Zura, MD
Duke University Medical Center
Department of Orthopaedic Surgery
Duke University Medical Center
Disclosures
None
Duke University Medical Center
Background
Ankle fracture-dislocations require urgent reduction
Protocol for management at DUMC
1) Reduction in ED
2) If congruent, splint and then clinic follow-up to schedule surgery
3) If incongruent, ORIF vs ex-fix based on soft tissue swelling
Difficult to predict which injuries can be adequately reduced
Duke University Medical Center
Fracture 1 Fracture 2
Background
Duke University Medical Center
Fracture 1: Unstable
Duke University Medical Center
Fracture 2: Stable
9/24/2015
2
Duke University Medical Center
Hypothesis
Unstable injuries will have:
Greater initial fracture displacement
Greater radiographic syndesmotic disruption
Larger posterior malleolus fracture size
Duke University Medical Center
Methods
243 patientsOperatively treated ankle
fractures (2008-2012)
Excluded:
Open fracture
Pilon
No reduction
Polytrauma
56 patients
Included:
Supination
Pronation
Bi/trimalleolar
Isolated
36 patients 20 patients
Unstable
-delayed ORIF
Stable
-urgent ORIF or ex-fix
Duke University Medical Center
Results: CategoricalUnstable Stable P-value
N 36 20
Injury Mechanism 0.728
Supination 28 (77.8%) 17 (85.0%)
Pronation 8 (22.2%) 3 (15.0%)
Fibular Comminution 0.760
None 8 (22.2%) 6 (30.0%)
Mild-moderate 20 (55.6%) 9 (45.0%)
Severe 8 (22.2%) 5 (25.0%)
Posterior Malleolus 0.084
Fractured 31 (86.1%) 12 (63.2%)
Intact 5 (13.9%) 7 (36.8%)
Talus Displacement
(coronal plane)
0.449
None 6 (17.6%) 5 (26.3%)
0-50% 14 (41.2%) 10 (52.6%)
50-100% 10 (29.4%) 2 (10.5%)
>100% 4 (11.8%) 2 (10.5%)
Talus Displacement
(sagittal plane)
0.864
None 20 (58.8%) 11 (57.9%)
0-50% 5 (14.7%) 4 (21.0%)
50-100% 7 (20.6%) 4 (21.0%)
>100% 2 (5.9%) 0 (0%)
Medial Injury 0.443
Bony 29 (87.9%) 15 (79.0%)
Ligamentous 4 (12.1%) 4 (21.0%)Duke University Medical Center
Results: ContinuousUnstable (mm) Stable (mm) P-value
N 36 20
MM Fragment Size 12.6 ± 6.6 9.0 ± 7.0 0.073
MM Fragment Displacement 12.7 ± 9.2 8.4 ± 8.9 0.107
Medial Clear space 5.9 (4.6, 8.4) 5.7 (4.7, 7.5) 0.886
Fibular Shortening 6.5 (3.7, 13.8) 4.4 (0.0, 5.7) 0.050
Fibular Sagittal Displacement 9.9 ± 8.4 6.4 ± 3.9 0.105
PM Fragment Size 6.2 (4.2, 8.5) 3.2 (0.0, 5.1) 0.011
PM Fragment Size (no zeros) 7.2 (5.1, 9.0) 4.8 (3.7, 6.7) 0.039
PM Intact Articular Surface 26.1 (20.0, 29.2) 23.1 (0.0, 29.1) 0.264
TF Clear Space 7.6 (4.8, 13.6) 6.2 (4.9, 8.0) 0.244
TF Overlap (AP view) 5.3 ± 4.5 6.1 ± 4.3 0.574
TF Overlap (mortise view) 0.0 (0.0, 4.2) 2.3 (0.0, 4.2) 0.509
Duke University Medical Center
Results
12 (52%)
19 (73%)
11 (48%)
7 (27%)
0
5
10
15
20
25
30
≤5 > 5
Nu
mb
er
(Pa
tien
ts)
Fibular Shortening (mm)
Stable
Unstable
Duke University Medical Center
Results
10 (59%)8 (24%)
2 (14%)
7 (41%)
26 (76%)
12 (86%)
0
10
20
30
40
≤ 0.1 > 0.1 > 0.2
Nu
mb
er
of
Pa
tien
ts
Posterior Malleolus Fracture Ratio
Unstable
Stable
9/24/2015
3
Duke University Medical Center
Results
Proportion Unstable
Fibular Shortening < 5mm and PM Ratio < 0.1 55.6% (5/9)
Fibular Shortening > 5mm and PM Ratio > 0.1 88.9% (16/18)
Fibular Shortening > 5mm and PM Ratio > 0.2 100% (6/6)
Duke University Medical Center
Results
Unstable Stable
Duke University Medical Center
Conclusions
Radiographic measurements can predict injury stability:
Posterior malleolus fragment size
Fibular shortening
Medial malleolus fragment size
Syndesmotic measurements, and talar displacement did not predict
injury stability
Further investigation
Outcomes with early vs. delayed operative management
Clinical utility of radiographic criteria
9/24/2015
1
Treatment trends of clavicular
shaft fractures
Brendan M. Patterson
North Carolina Orthopaedic
Association
October 2015
Background
Neer. JAMA. 1960
“reduction is practically impossible to maintain, and
patients do well with non-operative management”
Neer, CS. Rockwood and Green. 2nd ed.
Non-op vs ORIF
COTS. JBJS, 2007
P<0.01 for each time point
Non-op vs ORIF
COTS. JBJS, 2007
P<0.01
P=0.04
P=0.05 P<0.01
Non-op vs ORIF
COTS. JBJS, 2007
• ORIF:
• Higher satisfaction
• Improved cosmetic result
• Decreased complication rate
• Improved clinical outcomes
• Decreased non-union rate (3% vs 14%)
• Decreased time to union (16 weeks vs 28 weeks)
9/24/2015
2
Trends
Yang, et al. JPO. 2015
P < 0.001
P < 0.001
P < 0.001
Trends
Yang, et al. JPO. 2015
P = 0.007
P < 0.001
P < 0.001
Purpose
• Investigate the trends of operative vs non-operative treatment
• Determine if treatment trends differ based on patient age or sex
Methods
• Data obtained from the PearlDiver patient records database
» Database queried from 2007-2011
» Patients >20 years of age
» Diagnosis of closed clavicular shaft fracture. (ICD-9 810.02).
» Treatment with open vs closed treatment. (CPT 23500 vs 23515)
Methods
• Statistical analysis
» Rates of operative and non-operative treatment calculated
» Subgroup analysis performed based on patient age and sex
• Chi-squared analysis used to compare rates from 2007-2011
Results
25%
27%
29%
31%
33%
35%
37%
39%
41%
43%
45%
2007 2008 2009 2010 2011
% t
rea
ted
wit
h O
RIF
Year
Rate of operative fixation
9/24/2015
3
Results
15%
20%
25%
30%
35%
40%
45%
20 to 24 25 to 29 30 to 34 35 to 39 40 to 44 45 to 49 50 to 54 55 to 59 60 to 64 65 to 69
% t
rea
ted
wit
h O
RIF
Patient age
Operative treatment based on patient age
Results
30%
31%
32%
33%
34%
35%
36%
37%
38%
39%
40%
Male FemalePerc
en
t u
nd
erg
oin
g o
pera
tiv
e f
ixati
on
Patient sex
Operative treatment based on patient sex
Conclusions
• Trends in the treatment of clavicle fractures have increased
from 2007-2011.
• These trends are more pronounced among a younger, male
population.
• Increased rates of surgical management likely due to recent
literature to support operative fixation.
• This data provides an example of the impact of evidence based
medicine in orthopaedic surgery.
9/24/2015
1
Radiographic Measurements of Hip Dysplasia Correlate with Decreased Size of Acetabular Posterior Wall Fractures
Jason J. Halvorson, MD | Austin V. Stone, MD, PhD
Anna N. Miller, MD | Eben A. Carroll, MD
Department of Orthopaedic SurgeryWake Forest School of Medicine, Winston-Salem, NC
North Carolina Orthopaedic Association 2015 Annual Meeting, Kiawah Island, SC
Wake Forest Baptist Medical Center
Disclosures
Austin V. Stone MD, PhD
• Research Support: Smith & Nephew, LLC
Anna N. Miller, MD
• Consultant: Depuy-Synthes, Inc.
Eben A. Carroll, MD
• Consultant: Smith & Nephew, LLC; Depuy-Synthes, Inc.
• Institutional Support: Smith & Nephew, LLC; Depuy-Synthes, Inc.
Dr. Halvorson does not have anything to disclose.
Hypothesis
To determine if radiographic hip dysplasia measurements correlates to traumatic hip dislocation and posterior wall fragment size in acetabular fractures
648 reviewed105 posterior wall fractures
21 hip dislocations
Total patients = 126
Outcome Measures
• Radiographic• Injured LCE
• Cross over sign
• Posterior wall sign
P=0.004 P=0.57
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Posterior wall fracture size with traumatic hip dislocation
0% n=21
<40% n = 44
≥40% n=58
P=0.044
Discussion
Traumatic hip dislocations with smaller posterior wall fractures are associated with increased hip dysplasia\
Classic definitions of stable posterior wall may not be reflect stability in dysplastic hips
9/24/2015
1
Older Patients Really do
Break More Easily: Patient Age is Inversely Associated with Energy
of Collision Causing Fracture
Austin Stone, MD, PhD PGY 4
Wake Forest Baptist Medical Center
Wake Forest Baptist Medical Center
CONTRIBUTING AUTHORS
Usoro AO1, Weaver AA2, Wuertzer S3, Stitzel J2,
Lenchik L3, Miller AN4
1Wake Forest School of Medicine, Winston-Salem, NC2Virginia Tech-Wake Forest University Center for Injury Biomechanics, Winston-Salem, NC3Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC4Department of Orthopedic Surgery, Wake Forest School of Medicine, Winston-Salem, NC
Wake Forest Baptist Medical Center
INTRODUCTION
Increasing Age of US Population
↓
Increasing Number of Older Drivers
↓
Increased Geriatric Trauma Involved in
Motor Vehicle Crashes
Wake Forest Baptist Medical Center 4
Crash Injury Research and
Engineering Network (CIREN)
http://www.sbes.vt.edu/ciren/cirennetwork.html
Wake Forest Baptist Medical Center
STUDY DEMOGRAPHICS
THORAX
HEAD/FACE
UPPER EXTREMITY
SPINE
PELVIS/LOWER EXTREMITY
868 PATIENTS 60+ YEARS
900 PATIENTS 20 – 50 YEARS
Wake Forest Baptist Medical Center
RESULTS
Older Age is Associated with Decreased ∆V
R2 = 0.005
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Similar Trend Across Multiple Body Regions Similar Trend Seen for ∆Energy•
Wake Forest Baptist Medical Center
Energy Levels By Age Group
Fracture Type Ages 60+
p-value
Ages 20-50
p-valueThorax
- ∆V
- ∆Energy
<0.0001
<0.0001
<0.0001
<0.0001
Spine
- ∆V
- ∆Energy
<0.0001
<0.0001
0.80
0.80
Upper Extremity
- ∆V
- ∆Energy
<0.0001
0.001
0.93
0.13
Pelvis/ Lower Extremity
- ∆V
- ∆Energy
<0.0001
<0.0001
0.002
0.84
Wake Forest Baptist Medical Center
CLINICAL IMPLICATIONS
• Geriatric drivers require less energy to
sustain the same fractures as younger
drivers
• Age is correlated with energy required to
cause fracture
• Bone density may be important contributor
to fracture (even in “high energy” motor
vehicle crashes)