Neuro 14 Ascending Tracts Student

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    ASCENDING PATHWAYS

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    Ascending Pathways

    Three-neuron pathways:

    Primary sensory neurons:

    From external receptors

    Travel through dorsal roots of spinal cord

    Secondary neurons:

    Make up tracts in spinal cord and brainstem

    Tertiary neurons:From thalamus to primary sensory cortex

    Travel through internal capsule

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    Ascending Pathways

    For conscious perception:

    Spinothalamic system

    Medial Lemniscal system

    For unconscious perception:

    Spinocerebellar

    Spino-olivary

    SpinotectalSpinoreticular

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    Spinothalamic System

    Lateral spinothalamic tract

    Anterior spinothalamic tract

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    Lateral Spinothalamic Tract

    Carries pain and temperature

    Primary fibers ascend or descend 1-2spinal cord segments before synapsingwith secondary fibers.

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    Lateral Spinothalamic Tract

    Secondary axons decussate throughanterior gray and white commissures.

    Secondary axons make up the lateralspinothalamic tract traveling in the lateralcolumn of the spinal cord.

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    Lateral Spinothalamic

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    Lateral Spinothalamic Tract

    Secondary fibers are joined in brainstemby fibers of the trigeminothalamic tract:

    (Pain and temperature from face and teeth.)

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    Lateral Spinothalamic Tract

    Secondary fiber collaterals project toreticular formation:

    Stimulate wakefulness and consciousness.

    Secondary fibers project to ventralposterolateral (VPL) nucleus of thalamus.

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    Lateral Spinothalamic Tract

    Secondary fibers synapse with tertiaryfibers in VPL.

    Tertiary fibers (corticopetal fibers) synapsein postcentral gyrus:

    Somatic sensory areas 3, 1, 2

    Tertiary fibers form part of internalcapsule.

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    Anterior Spinothalamic Tract

    Carries light touch (crude touch), pressure,tickle, itch

    Primary neurons may ascend 8-10 spinal

    cord segments before synapsing withsecondary neurons.

    Secondary fibers decussate in anterior

    gray or white commissures.

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    Anterior Spinothalamic Tract

    Secondary fibers ascend to synapse withtertiary fibers in VPL nucleus of thalamus.

    Tertiary fibers ascend through internal

    capsule to primary sensory cortex.

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    Lateral Spinothalamic Tract

    Red

    1

    Blue

    2

    Green

    3

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    Lateral Spinothalamic Tract

    Red

    1

    Blue

    2

    Green

    3

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    Anterior Spinothalamic

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    Anterior Spinothalamic Tract

    Red:

    1

    Blue

    2

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    Anterior Spinothalamic Tract

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    Medial Lemniscus System

    Also called posterior column system.

    Carries sensations for two-point sensation(fine touch), pressure, and vibration.

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    Medial Lemniscus System

    Primary fibers ascend entire length ofspinal cord and synapse with secondaryneurons in medulla:

    Fasciculus gracilis

    Fasciculus cuneatus

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    Medial Lemniscus

    Red:

    Gracilis

    Blue

    cuneatus

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    Medial Lemniscus System

    Fibers of fasciculus gracilis synapse innucleus gracilis:

    Convey sensations from below midthoracic level.

    Fibers of fasciculus cuneatus synapse innucleus cuneatus:

    Convey sensations from above midthoracic level.

    Also conveys proprioceptive sensation from arms tocerebellum.

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    Medial Lemniscus System

    Secondary fibers decussate.

    Secondary fibers ascend to synapse inVPL of thalamus.

    Tertiary fibers ascend through internalcapsule to primary sensory cortex.

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    Medial Lemniscus

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    Medial Lemniscus

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    Posterior Spinocerebellar Tract

    Originates in thoracic and upper lumbarregions.

    Consists of uncrossed fibers that entercerebellum through inferior cerebellarpeduncles.

    Transmits ipsilateral proprioceptiveinformation to cerebellum.

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    Anterior Spinocerebellar Tract

    Originates in lower trunk and lower limbs.

    Consists of crossed fibers that recross inpons and enter cerebellum throughsuperior cerebellar peduncles.

    Transmits ipsilateral proprioceptiveinformation to cerebellum.

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    Spinocerebellar Tracts

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    Spino-Olivary Tracts

    Project to accessory olivary nuclei andcerebellum.

    Contribute to movement coordinationassociated primarily with balance.

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    Spinotectal Tracts

    Project to superior colliculi of midbrain.

    Involved in reflexive turning of the headand eyes toward a point of cutaneousstimulation.

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    Spinoreticular Tracts

    Involved in arousing consciousness in thereticular activating system throughcutaneous stimulation.

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    Stretch (myotactic) Reflex

    Muscle spindle = receptor:

    3-10 small, specialized intrafusal muscle fibers:

    Contractile only at ends.

    Non-contractile center.

    Afferent neurons from center of intrafusal fiberstravel through dorsal root of spinal nerve tosynapse directly with alpha motor neurons of

    extrafusal fibers in which muscle spindle isembedded.

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    Stretch (myotactic) Reflex

    Afferent neurons from muscle spindle alsosynapse with ascending fibers withinspinal cord.

    Gamma motor neurons supply intrafusalfibers of muscle spindle:

    Regulate sensitivity of intrafusal fibers.

    Gamma neurons are modulated by

    descending fibers within spinal cord. Refer to syllabus for specific stretch

    reflexes.

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    Golgi-Tendon Reflex

    Golgi tendon organs:

    Encapsulated nerve endings:

    End with numerous terminal branches with

    small swellings associated with individualtendon fascicles.

    Lie within tendons near the muscle-tendon

    junction.Stimulated when tendon is stretched.

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    Golgi-Tendon Organs/Reflex

    Afferent neurons from Golgi organs passthrough dorsal root of spinal nerve andsynapse with inhibitory association

    neurons in posterior gray matter of spinalcord.

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    Golgi-Tendon Organs/Reflex

    Association neurons synapse with alphamotor neurons that innervate muscle fibersassociated with tendon.

    Causes relaxation of associated musclesand prevents damage to the tendon due toexcessive tension.