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JANUARY 1990 VOL 53 NO 1
Journal of
1N LU#tROJLOGYgNEUROSUJRGERY
; &PSYCHIATRYEditorialannouncement 1 History of the journal and change of style
Editorial 2 Tropical spastic paraparesis and human T-cell lymphotropic virus type 1 P Rudge
Papers 4 A cluster ofHTLV-1 associated tropical spastic paraparesis in Equateur (Zaire): ethnic and familialdistribution K Kayembe, P Goubau, J Desmyter, R Vlietinck, H Carton
11 CT, MR and SPECT imaging in temporal lobe epilepsy Roderick Duncan, James Patterson,DonaldM Hadley, Peter Macpherson, Martin J Brodie, Ian Bone, Anne P McGeorge, David J Wyper
16 A prospective study of acute cerebrovascular disease in the community: the Oxfordshire ComrmunityStroke Project 1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebralinfarction, primary intracerebral and subarachnoid haemorrhage J Bamford, P Sandercock, M Dennis,J Burn, C Warlow
23 Frontal lobe dementia and motor neuron disease D Neary, J S Snowden, D M A Mann, B Northen,P J Goulding,N Macdermott
33 Measurements of regional cerebral blood flow and cognitive performance in Alzheimer's diseaseD Montaldi, D N Brooks, J H McColl, D Wyper, J Patterson, E Barron, J McCulloch
39 Scoliosis in rats with experimentally-induced hemiparkinsonism: dependence upon striatal dopaminedenervation Mario Herrera-Marschitz, Hiroya Utsumi, Urban Ungerstedt
44 Pain-related somatosensory evoked potentials in cortical reflex myoclonus Ryusuke Kakigi,Hiroshi Shibasaki, Ryuji Neshige, Akio Ikeda, Kousuke Mamiya, Yasuo Kuroda
49 Jitter in the muscle fibre J V Trontelj, E Stdlberg,M Mihelin55 EMG responses in leg muscles to postural perturbations in Huntington's disease J Huttunen, V Homberg63 Is the EEG really normal in lacunar stroke? L J Kappelle, A C van Huffelen, J van Gijn67 Vertical gaze palsy and selective unilateral infarction of the rostral interstitial nucleus of the medial
longitudinal fasciculus (riMLF) J Bogousslavsky, J Miklossy, F Regli, R Janzer72 Herpes simplex virus 1 infection upregulates stress protein expression in cultured retinal neurons
P G E Kennedy,M Wakakura, W S Foulds, G B Clements
Short reports 76 Cerebrotendinous xanthomatosis: clinical and MRI study (a case report) Marco Fiorelli, Vittorio Di Piero,Stefano Bastianello, Luigi Bozzao, Antonio Federico
79 A case of progressive aphasia without dementia: "temporal" Pick's disease? Ph Scheltens, G J Hazenberg,J Lindeboom, J Valk, E Ch Wolters
81 The blood/cerebrospinal fluid partitioning of pyrazinamide: a study during the course of treatment oftuberculous meningitis Prida Phuapradit, K Supmonchai, S Kaojarern, C Mokkhavesa
83 Persistent periodic hiccups following brain abscess: a case report P H P Jansen, EM G Joosten,HM Vingerhoets
85 Congenital Homer's syndrome with unilateral facial flushing H Saito
Letters 87 Spasms C Pallis87 Pontine myelinolysis presenting with acute parkinsonism as a sequel of corrected hyponatraemia R Tinker,
M G Anderson, P Anand, A Kermode, A E Harding88 Visual hallucinations and the cholinergic system in dementia EK Perry, J Kerwin, R H Perry, G Blessed,
A F Fairbairn88 Type 1 Arnold-Chiari malformation in a 77 year old woman D M G Halpin, P Trend, L Symon,
A E Harding89 Matters arising90 Book reviews92 Notice
BRITISH MEDICAL ASSOCIATION TAVISTOCK SQUARE LONDON WC1H 9JR
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VOLUME 53 CONTENTS
No 1 JANUARY 1990 Page Editorial announcement1 History of the journal and change of style
Editorial2 Tropical spas\tic paraparesis and human T-cell lymphotropic virus type 1 P Rudge
Papers4 A cluster ofHTLV-1 associated tropical spastic paraparesis in Equateur (Zaire): ethnic and familial distribution
K Kayembe, P 6oubau, J Desmyter, R Vlietinck, H Carton11 CT, MR and SPECT imaging in temporal lobe epilepsy Roderick Duncan, James Patterson, Donald M Hadley,
Peter Macpherson, Martin J Brodie, Ian Bone, Anne P McGeorge, David J Wyper16 A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project
1981-86. 2. Incidence, case fatality rates and overall outcome at one year of cerebral infarction, primaryintracerebral and subarachnoid haemorrhage J Bamford, P Sandercock, M Dennis, J Burn, C Warlow
23 Frontal lobe dementia and motor neuron disease D Neary, J S Snowden, DM A Mann, B Northen, P J Goulding,N Macdermott
33 Measurements of regional cerebral blood flow and cognitive performance in Alzheimer's disease D Montaldi,D N Brooks, J H McColl, D Wyper, J Patterson, E Barron, J McCulloch
39 Scoliosis in rats with experimentally-induced hemiparkinsonism: dependence upon striatal dopamine denervationMario Herrera-Marschitz, Hiroya Utsumi, Urban Ungerstedt
44 Pain-related somatosensory evoked potentials in cortical reflex myoclonus Ryusuke Kakigi, Hiroshi Shibasaki,Ryuji Neshige, Akio Ikeda, Kousuke Mamiya, Yasuo Kuroda
49 Jitter in the muscle fibre J V Trontelj, E Stclberg,M Mihelin55 EMG responses in leg muscles to postural perturbations in Huntington's disease J Huttunen, V Homberg63 Is the EEG really normal in lacunar stroke? L J Kappelle, A C van Huffelen, J van Gijn67 Vertical gaze palsy and selective unilateral infarction of the rostral interstitial nucleus of the medial longitudinal
fasciculus (riMLF) J Bogousslavsky, J Miklossy, F Regli, R Janzer72 Herpes simplex virus 1 infection upregulates stress protein expression in cultured retinal neurons P G E Kennedy,
M Wakakura, W S Foulds, G B Clements
Short reports76 Cerebrotendinous xanthomatosis: clinical and MRI study (a case report) Marco Fiorelli, Vittorio Di Piero,
Stefano Bastianello, Luigi Bozzao, Antonio Federico79 A case of progressive aphasia without dementia: "temporal" Pick's disease? Ph Scheltens, G J Hazenberg,
J Lindeboom, J Valk, E Ch Wolters81 The blood/cerebrospinal fluid partitioning of pyrazinamide: a study during the course of treatment of tuberculous
meningitis Prida Phuapradit, K Supmonchai, S Kaojarern, C Mokkhavesa83 Persistent periodic hiccups following brain abscess: a case report P H P Jansen, EM G Joosten,HM Vingerhoets85 Congenital Horner's syndrome with unilateral facial flushing H Saito
Letters87 Spasms C Pallis87 Pontine myelinolysis presenting with acute parkinsonism as a sequel of corrected hyponatraemia R Tinker,
M G Anderson, P Anand, A Kermode, A E Harding88 Visual hallucinations and the cholinergic system in dementia EK Perry, J Kerwin, R H Perry, G Blessed,
A F Fairbairn88 Type 1 Arnold-Chiari malformation in a 77 year old woman D M G Halpin, P Trend, L Symon, A E Harding89 Matters arising90 Book reviews92 Notice
No 2 FEBRUARY 1990 Editorial93 The modern management of Parkinson's disease Niall Quinn
Papers96 Subcutaneous apomorphine in the treatment of Parkinson's disease J P Frankel, A J Lees, P A Kempster,
G M Stern102 Nasogastric and intravenous infusions of ( + )-4-propyl-9-hydroxynaphthoxazine (PHNO) in Parkinson's disease
R J Coleman, N P Quinn,M Traub, C D Marsden106 Syringomyelia and arachnoiditis L R Caplan, A B Norohna, L L Amico114 Simultaneous VEP and PERG investigations in early Parkinson's disease S Calzetti, A Franchi, G Taratufolo,
. Groppi118 A cerebral hemisphere influence on cutaneous vasomotor reflexes in humans A-G Herbaut, J D Cole,
EM Sedgwick121 Disturbances in ocular sympathetic function and facial blood flow in unilateral migraine headache
Peter D Drummond126 Recovery of elbow function in voluntary positioning of the hand following hemiplegia due to
stroke Alan M Wing, Sinclair Lough, Ailie Turton, Carole Fraser, John R Jenner135 Somatosensory findings in postherpetic neuralgia Turo Nurmikko, David Bowsher142 Neuropsychological assessment in patients with relapsing-remitting multiple sclerosis and mild functional
impairment: correlation with magnetic resonance imaging G P Anzola, L Bevilacqua, S F Cappa, R Capra,L Faglia, E Farina, G Frisoni, C Mariani,M P Pasolini, L A Vignolo
146 Some clinical and pathological observations on chronic myelopathy: a variant of multiple sclerosisB G Weinshenker, J J Gilbert, G C Ebers
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150 Lateralisation of cortical function during cognitive tasks: regional cerebral blood flow studies of normal individualsand patients with schizophrenia K F Berman, D R Weinberger
161 A quantitative study of the neurofibrillary tangles and the choline acetyltransferase activity in the cerebral cortexand the amygdala in Alzheimer's disease Margaret M Esiri, R C A Pearson, Janet E Steele, D M Bowen,T P S Powell
Short reports166 Magnetic resonance imaging of the brain and spinal cord in cerebrotendinous xanthomatosis K S Bencze,
D R Vande Polder, L D Prockop168 Oral dyskinesias associated with bilateral thalamo-capsular infarction 0 Combarros, A Gutiirrez, J Pascual,
J Berciano170 HLA antigens in chronic inflammatory demyelinating polyneuropathy D J Feeney, J D Pollard, J G McLeod,
G J Stewart, T J Doran
Letters173 Numb chin syndrome in the elderly Tetsuo Furukawa173 Methylprednisolone therapy in tropical spastic paraparesis John Duncan, Peter Rudge174 Trunkal myoclonus with spontaneous priapism and seminal ejaculation in Wilson's disease K Rajasekharan Nair,
P Gopala Pillai174 Increased amplitude of F-response in Lambert-Eaton myasthenic syndrome M Henriet, J Jacquy174 Subarachnoid haemorrhage related to a lumbosacral fusion - a case report A B Jamjoom, J B L Tan175 Spinal arteriovenous malformation unmasked during intravenous urography H J Willison, P Trend, P K Thomas,
L Symon, B E Kendall, D Thrush177 Proceedings of the meeting of the Association of British Neurologists, London, 28-30 September 1989183 Book reviews184 Notices
No 3 MARCH 1990 Editorial185 Ticlopidine, a new antithrombotic drug: but is it better than aspirin for longterm use? Charles Warlow
The Cairns Memorial Lecture188 The Cairns Tradition Peter H Schurr
Papers194 Abnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. I Abducens
palsy A M Bronstein, Joan Morris, G du Boulay,M A Gresty, P Rudge200 Abnormalities of horizontal gaze. Clinical, oculographic and magnetic resonance imaging findings. II Gaze palsy
and internuclear ophthalmoplegia A M Bronstein, P Rudge,M A Gresty, G du Boulay, Joan Morris208 Pathological stretch reflexes on the "good" side of hemiparetic patients A F Thilmann, S J Fellows, E Garms215 Observations on the reflex effects seen in Parkinson's disease on terminating a period of tendon vibration
P B C Matthews, F W J Cody, Helen C Richardson, N MacDermott220 A comparison of the effects of controlled-release levodopa (Madopar CR) with conventional levodopa in late
Parkinson's disease D G MacMahon, D Sachdev, H G Boddie, C J K Ellis, B R Kendal, N A Blackburn224 Severity of Parkinson's disease is a risk factor for peak-dose dyskinesia M W I M Horstink, J C M Zijlmans,
J W Pasman, H J C Berger,M A van't Hof227 Peripheral nerve functions in chronic alcoholic patients on disulfiram: a six month follow up Sarala K Palliyath,
Barry D Schwartz, Linda Gant231 Abnormality in the cavernous sinus in three patients with Tolosa-Hunt syndrome: MRI and CT findings
Yoshinobu Goto, Shinichi Hosokawa, Ikuo Goto, Ryousuke Hirakata, Kanehiro Hasuo235 Stroke risk and critical carotid artery stenosis J W Norris, C Z Zhu238 Feasibility of percutaneous transluminal angioplasty for carotid artery stenosis Martin M Brown, Paul Butler,
Jeremy Gibbs, Michael Swash, John Waterston244 Disappearing brain lesions, psychosis and epilepsy: a report of two cases Anthony Feinstein, Maria Ron,
Simon Wessely247 Sensory and cognitive event-related potentials in myalgic encephalomyelitis Deepak Prasher, Alison Smith,
Leslie Findley254 Pseudodementia twelve years on Perminder S Sachdev, J Sydney Smith, Heather Angus-Lepan, Paul Rodriguez
Short reports260 Onset and offset of electromyographic (EMG) silence in asterixis Yoshikazu Ugawa, Kieko Genba,
Tomoyuki Shimpo, Toru Mannen263 Pure agraphia after deep left hemisphere haematoma B Croisile, B Laurent, D Michel,M Trillet
Letters266 Persistent segmental cerebral artery constrictions in coital cephalgia R Kapoor, B E Kendall,M J G Harrison267 Resolution of a severe sensorimotor neuropathy following resection of an associated asymptomatic gastric
lymphoma T P Enevoldson, J A Ball, JM McGregor268 Dysphagia due to a pharyngeal mucocoele mimicking myasthenia Sylvain S Junger, Robert B Wright268 Trazodone is ineffective in essential tremor Lynn Cleeves, Leslie J Findley269 Low prevalence of HTLV-1 antibodies in the serum of patients with tropical spastic paraplegia from the Ivory
Coast J Hugon, J M Vallat, M Dumas, M Verdier, F Denis, F Akani, Y F Boa, C Giordano269 Wegener's granulomatosis presenting as peripheral neuropathy: diagnosis confirmed by serum
anti-neutrophil antibodies W Dickey, W J Andrews270 Matters Arising271 Book Reviews
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No 4 APRIL 1990
No 5 MAY 1990
Editorial273 Progress in the treatment of epilepsy C D Binnie
Papers275 The pattern of depressive symptoms varies with progression of Parkinson's disease Steven J Huber,
Donald L Freidenberg, George W Paulson, Edwin C Shuttleworth, Jeffrey A Christy279 Movement amplitude choice reaction time performance in Parkinson's disease may be independent of dopaminergic
status Seth L Pullman, Ray L Watts, Jorge L Juncos, Jerome N Sanes284 Antisaccades and remembered saccades in Parkinson's disease C J Lueck, S Tanyeri, T J Crawford, L Henderson,
C Kennard289 Oxidative polymorphism of debrisoquine in Parkinson's disease J Benitez, JM Ladero, F J Jimenez-Jimenez,
C Martinez, A M Puerto,M J Valdivielso, A Llerena, J Cobaleda, J J Mufioz293 Neuropsychological deficits in symptomatic minor head injury patients after concussion and mild concussion
Bruce E Leininger, Sandy E Gramling, Albert D Farrell, Jeffrey S Kreutzer, Edward A Peck III297 Idiopathic cerebellar ataxia of late onset: natural history and MRI morphology T Klockgether, G Schroth,
H-C Diener, J Dichgans306 Disturbances in human arm movement trajectory due to mild cerebellar dysfunction S H Brown,H Hefter,
M Mertens, H-J Freund314 Excitatory amino acid binding sites in the hippocampal region of Alzheimer's disease and other dementias
J B Penney, W F Maragos, J T Greenamyre, D L Debowey, Z Hollingsworth, A B Young321 Enhancement of recurrent inhibition by intravenous administration of L-acetylcarnitine in spastic patients
Riccardo Mazzocchio, Marco Schieppati, Chiara Scarpini, Alessandro Rossi327 Cyclosporin A in the treatment of chronic demyelinating polyradiculoneuropathy S J Hodgkinson, J D Pollard,
J G McLeod331 Relationship between electrical and mechanical properties of motor units T Vogt, WA Nix, B Pfeifer335 Pure agraphia of kanji due to thrombosis of the Labbe vein Takanori Yokota, Sumio Ishiai, Tetsuo Furukawa,
Hiroshi TsukagoshiShort reports
339 Bitemporal hypoperfusion in transient global amnesia: 99m-Tc-HM-PAO SPECT and neuropsychologicalfindings during and after an attack Georg Stillhard, Theodor Landis, Regula Schiess, Marianne Regard,Gregorio Sialer
343 Episodic paroxysmal hemicrania: a further case and review of the literature JN Blau, H Engel345 Circadian rhythms in the body temperatures of intensive care patients with brain lesions W A Dauch, S Bauer348 Diaphragmatic weakness in hereditary motor and sensory neuropathy R Hardie, A E Harding, N Hirsch,
C Gelder, A D Macrae, P K Thomas351 Short latency evoked potentials: new criteria for brain death? E Facco, M Casartelli Liviero,M Munari,
F Toffoletto, F Baratto, G P Giron354 Progression of acute hydrocephalus in subarachnoid haemorrhage: a case report documented by serial CT scanning
Gabriel J E Rinkel, Eelco FM Wijdicks, Lino M P Ramos, Jan van Gijn356 Acute triphenyltin intoxication: a case report R-M Wu, Y-C Chang, H-C Chiu
Letters358 An unusual complication of mourning A W Harrop-Griffiths, NP Hirsch, B Kendall, L Symon358 Chronic polyradiculoneuropathy associated with human T-cell lymphotropic virus type I infection
Kenji Arakawa, Hirotoshi Umezaki, Shousaku Noda, Hiroaki Itoh359 Carotid gustatory syndrome in a patient with Holmes-Adie syndrome Hiroshi Shibasaki, Hideaki Tomi359 The relationship of memory and cognition in Parkinson's disease to lateralisation of motor symptoms
Manuel Riklan, Constance Reynolds, Stanley Stellar360 Pseudotumour cerebri with focal neurological deficit Sally B Zachariah, Lissette Jimenez, Babu Zachariah,
Leon D Prockop361 Matters Arising362 Book Reviews364 Notice
Occasional Review365 The diagnosis of subarachnoid haemorrhage M Vermeulen, J van Gijn
Papers373 The occult aftermath of boxing Gareth W Roberts, David Allsop, Clive Bruton379 Dissection of the cervical internal carotid artery. The role of Doppler/Duplex studies and conservative management
M S M Eliamel, P R D Humphrey,MDM Shaw384 Laboratory testing of muscle function in the management of neuromuscular disease CM Wiles, Y Karni,
J Nicklin388 Multivariate analyses of factors associated with unemployment in people with multiple sclerosis Marit Gronning,
Einar Hannisdal, Svein Ivar Mellgren391 Electrocutaneous reflexes and multimodality evoked potentials in multiple sclerosis W G Friedli, P Fuhr398 First pain event related potentials to argon laser stimuli: recording and quantification L Arendt-Neilsen405 Second pain event related potentials to argon laser stimuli: recording and quantification L Arendt-Nielsen411 An empirical model for analysing and interpreting ventricular measures Campbell Clark, Randy Marbeck,
David Li416 Morphometry of the corpus callosum in monozygotic twins discordant for schizophrenia: a magnetic resonance
imaging study Manuel F Casanova, Richard D Sanders, Terry E Goldberg, Llewellyn B Bigelow, George Christison,E Fuller Torrey, Daniel R Weinberger
422 Contralateral and ipsilateral disorders of visual attention in patients with unilateral brain damage Guido Gainotti,Laura Giustolisi, Ugo Nocentini
427 Stereotaxic thalamotomy-experiences from the levodopa era K Wester, E Hauglie-Hanssen
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Short reports431 Multiple brain abscesses from isolated cerebral mucormycosis Alfonso Escobar, Oscar H Del Brutto434 HLA antigens in multiple sclerosis of Northern Spanish population C L6pez-Larrea, D F Uria, Eliecer Coto
Letters436 Marijuana for Parkinsonian tremor J P Frankel, A Hughes, A J Lees, G M Stern436 Unilateral cerebellar damage in focal epilepsy Roderick Duncan, James Patterson, Donald M Hadley, Ian Bone437 Syringomyelia with spontaneous resolution Kazumasa Sudo, Shizuki Doi, Yasunori Maruo, Kunio Tashiro,
Satoshi Terae, Kazuo Miyasaka, Toyohiko Isu438 Syringomyelia associated with a spinal schwannoma: a case report A B Jamjoom, K G Davies439 Cervical cord compression and femoral neuropathy in hereditary multiple exostoses D A Nunez, H K Graham,
J A Fixsen440 Stuttering pituitary apoplexy resembling meningitis J B Winer, G Plant440 Intracranial haemorrhages occurring in the idiopathic hypereosinophilic syndrome S Roche, S Cross, B Kaufman441 Meningitis and spinal subdural empyema as a complication of sinusitis R Harries-Jones, M Hernandez-Bronchud,
P Anslow, C J Davis441 Familial cerebellar ataxia and possible cosegregation with an inversion in chromosome 4 I D Young, D P Duckett442 Matters arising443 Proceedings of the meeting of the Society of British Neurological Surgeons450 Book reviews
No 6 JUNE 1990 Editorial453 Choosing cases and controls in neurological research C N Martyn
Occasional review455 Norman Dott's contribution to aneurysm surgery Nicholas V Todd, Jane E Howie, J Douglas Miller
Papers459 Geographical distribution of cases of Creutzfeldt-Jakob disease in England and Wales 1970-84 S N Cousens,
R Harries-Jones, R Knight, R G Will, P G Smith, W B Matthews466 The influence of the extent of surgery on the neurological function and survival in malignant glioma.
A retrospective analysis in 243 patients Ch J Vecht, C J J Avezaat, W L J van Putten, WM H Eijkenboom,S Z Stefanko
472 Management of focal intracranial infections: is medical treatment better than surgery? D Leys, J L Christiaens,Ph Derambure, J P Hladky, F Lesoin,M Rousseaux,M Jomin, H Petit
476 Cerebral radiation necrosis complicating stereotactic radiosurgery for arteriovenous malformation P Statham,P Macpherson, R Johnston, D M Forster, J Hume Adams, N V Todd
480 Sexual function in patients with Parkinson's disease and their partners R G Brown,M Jahanshahi, N Quinn,C D Marsden
487 Do visual field deficits exacerbate visuo-spatial neglect? P W Halligan, J C Marshall, D T Wade492 Mesolimbocortical dementia: clinico-pathological studies on two cases M Anthony Verity, B Roitberg, J J Kepes496 Saccadic function in spasmodic torticollis R Stell, A M Bronstein,M Gresty, D Buckwell, C D Marsden502 Neuromuscular function and plasma drug levels in pyridostigmine treatment of myasthenia gravis U Breyer-
Pfaff, A Schmezer, U Maier, A Brinkmann, F Schumm507 Acute effects of electromagnetic stimulation of the brain on cortical activity, cortical blood flow, blood pressure and
heart rate in the cat: an evaluation of safety J A Eyre, P A Flecknell, B R Kenyon, T H H G Koh, S MillerShort reports
514 Neuroleptic malignant syndrome A V Srinivasan,M Murugappan, S G Krishnamurthy, Zaheer Ahmed Sayeed517 Neuroleptic malignant syndrome and hypothyroidism A P Moore, I A Macfarlane, L D Blumhardt519 Vermal infarct with pursuit eye movement disorders Charles Pierrot-Deseilligny, Pierre Amarenco,
Etienne Roullet, Reni Marteau522 Restless legs syndrome and nocturnal myoclonus: initial clinical manifestation of familial amyloid polyneuropathy
F Salvi, P Montagna, R Plasmati, G Rubboli, F Cirignotta, M Veilleux, E Lugaresi, C A Tassinari526 Blink reflexes and magnetic resonance imaging in focal, unilateral central trigeminal pathway demyelination
L Kiers, WM CarrollLetters
530 Treatment of bruxism with botulinum toxin injections Michel van Zandijcke, Marcel M B Marchau530 Internal carotid artery dissection and ipsilateral hypoglossal nerve palsy Alain Vighetto, Fabrice Lisovoski,
Anne Revol, Marc Trillet, Gilbert Aimard531 Development of multifocal haemorrhage in a cerebral infarct during computed tomography C L Franke,
L M P Ramos, J van Gijn532 Internuclear ophthalmoplegia in giant-cell arteritis P Trend, E Graham533 Periodic fever: an unusual manifestation of a recurrent Rathke's cleft Bob J van Hilten, Raymund A C Roos,
Henri M de Bakker, Frits C de Beer534 Opsoclonus as a presenting symptom in thymic carcinoma M Schwartz, B Sharf, J Zidan534 Standard neurodiagnostic tests in Sydenham's chorea R F Gledhill, P D Thompson535 Matters arising536 Book reviews540 Notice
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No 7 JULY 1990
No 8 AUGUST 1990
Editorial541 Focal brain radiotherapy P N Plowman
Papers542 Complications of cerebral angiography for patients with mild carotid territory ischaemia being considered for
carotid endarterectomy Graeme J Hankey, Charles P Warlow, Andrew J Molyneux549 Non-invasive radiological investigation for oculomotor palsy Evelyn Teasdale, Patrick Statham, John Straiton,
Peter Macpherson554 Double blind study of intrathecal beta-interferon in multiple sclerosis: clinical and laboratory results C Milanese,
A Salmaggi, L La Mantia, A Campi,M Eoli,M Savoiardo, G Bianchi, A Nespolo558 Peripheral neuropathy profile in various groups of diabetics Pamela M Le Quesne, Clare J Fowler,
Nicholas Parkhouse564 Normal pressure hydrocephalus: did publications alter management? Jan Vanneste, Rob van Acker569 L-3, 4-dihydroxyphenylalanine (levodopa) lowers central nervous system S-adenosylmethionine concentrations in
humans R Surtees, K Hyland573 High incidence of endogenous depression in migraine: confirmation by tyramine test Joan Jarman,
Margaret Fernandez, P T G Davies, Vivette Glover, T J Steiner, C Thompson, F Clifford Rose,M Sandler576 Assessing motor impairment after stroke: a pilot reliability study Christine Collin, Derick Wade580 Parkinson's disease and driving ability P Madeley, J L Hulley, H Wildgust, R H S Mindham583 Motor set in Parkinson's disease C Robertson, K A Flowers593 Covert orienting attention in Parkinson's disease Tatsuo Yamada, Mutsuo Izyuuinn, Michael Schulzer,
Keizo Hirayama597 Cognitive impairments and depression in Parkinson's disease: a follow up study Sergio E Starkstein,
Paula L Bolduc, Helen S Mayberg, Thomas J Preziosi, Robert G Robinson603 Selective deficits in cognition and memory in high-functioning Parkinsonian patients Erich Mohr, Jorge Juncos,
Christiane Cox, Irene Litvan, Paul Fedio, Thomas N Chase607 Comprehension of prosody in Huntington's disease Lynn J Speedie, Nancy Brake, Susan E Folstein,
Dawn Bowers, Kenneth M Heilman611 Assessment of anomalous sentences repetition test G S Rai, K Stewart, L C Scott
Short reports613 Renal cell carcinoma presenting as Garcin's syndrome S I Mubaidin, J B Sunna,M A Beiruti,MM Shennak,
M S Ayoub615 Miller Fisher syndrome associated with Q fever Antonio Diaz Ortufio, Concepccion Maeztu, Jose A Mufnoz,
Rosa Reigadas, Tomds Rodriguez, Mariano Valdes617 Unusual MRI appearance of diffuse subcortical heterotopia or "double cortex" in two children J H Livingston,
J Aicardi
Letters621 Recurrent spontaneous accessory neuropathy C Chalk,H Isaacs621 Pesticide toxicity and motor neuron disease G B Steventon, R H Waring, A C Williams622 (+ )-PHNO: a new anti-Parkinsonian agent which does not induce chorea in MPTP-treated squirrel monkeys
NM J Rupniak, S Boyce,M J Steventon, S D Iversen623 Delayed onset posthemiplegic dystonia and imitation synkinesia Cheng-Yang Chiang, Chin-Song Lu623 Magnetic resonance imaging in adrenoleukodystrophy presenting as spinocerebellar degeneration I Miyai,
H Fujimura, T Umekage, K Watase, S Ueno, S Yorifuji,M Takahashi, S Tarui624 Myasthenia gravis and thymoma in multiple endocrine neoplasia (MEN-1) syndrome L JHM Vroegindeweij-
Claessens, C C Tijssen, G JM Creemers, J HM Lockefeer, J L JM Teepen625 Matters arising626 Book reviews628 Notices
Editorial629 The widening spectrum of infectious neurological disease P G E Kennedy
Papers633 Botulinum toxin treatment of cranial-cervical dystonia, spasmodic dysphonia, other focal dystonias and hemifacial
spasm J Jankovic, K Schwartz, D T Donovan640 Botulinum toxin treatment in spasmodic torticollis J D Blackie, A J Lees644 Central nervous system haemangioblastoma: a clinical and genetic study of 52 cases A M Boughey,NA Fletcher,
A E Harding649 Vesicular changes in the myopathies of AIDS. Ultrastructural observations and their relationship to zidovudine
treatment P K Panegyres, JM Papadimitriou, PN Hollingsworth, J A Armstrong, B A Kakulas656 The relationship of antibody levels to the clinical spectrum ofhuman neurocysticercosis D Zini, V J R Farrell,
A A Wadee662 Intrathecal synthesis of anti-mycobacterial antibodies in patients with tuberculous meningitis. An immunoblotting
study C JM Sindic, D Boucquey,M P Van Antwerpen, M C Baelden, C Laterre, C Cocito667 Clinical and genetic heterogeneity in early onset cerebellar ataxia with retained tendon reflexes A Filla,
G De Michele, F Cavalcanti, A Perretti, L Santoro, F Barbieri, G D'Arienzo, G Campanella671 Low plasma iron status and akathisia A Barton, J Bowie,K Ebmeier675 Hemiparetic multiple sclerosis J Cowan, I E C Ormerod, P Rudge681 Extradural implantation of sacral anterior root stimulators D Sauerwein, W lngunza, J Fischer, H Madersbacher,
C E Polkey, G S Brindley, P Colombel, P Teddy685 Bimanual simultaneous motor performance and impaired ability to shift attention in Parkinson's disease
M W I M Horstink, H J C Berger, K PM van Spaendonck, JH L van den Bercken, A R Cools
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Short reports691 The treatment of Gilles de la Tourette syndrome by limbic leucotomy M Robertson, M Doran, M Trimble,
A J Lees695 Stiffmnan syndrome: a rare paraneoplastic disorder? D E Bateman, R 0 Weller, P Kennedy697 LDH isoenzymes in cerebrospinal fluid in various brain tumours Y Lampl, Y Paniri, Y Eshel, I Sarova-Pinhas700 Misperceptions of comprehension difficulties of stroke patients by doctors, nurses and relatives R McClenahan,
M Johnston, Y Densham702 Practice effects on the preprogramming of discrete movements in Parkinson's disease C J Worringham,
G E Stelmach705 Transcranial magnetic stimulation can influence the selection of motor programmes K Ammon, S C Gandevia
Letters708 Occupational meralgia paraesthetica E Garcia-Albea, F Palomo, J Tejeiro, F Cabrera708 Vertical gaze palsy due to a resolving midbrain lesion P StJ Trend, B D Youl,MD Sanders, R S Kocen,
W I McDonald709 Mumps and Guillain-Barre syndrome S Duncan, R G Will, J Catnach709 The role of combined valve prolapses in the prognosis of cerebro-vascular ischaemic attacks associated with mitral
valve prolapse J Matias-Guiu, R Martin, R Insa, J M Molto, J Alvarez, A Codina, J Candell,JM Martinez- Vazquez
710 MRI of thoracic cord in tropical spastic paraparesis A G Kermode, P Rudge, A J Thompson, E P G H du Boulay,W I McDonald
710 Lewy bodies and subacute sclerosing panencephalitis WR G Gibb, F Scaravilli, J Michaud711 Combined neuroleptic malignant syndrome and the central anticholinergic syndrome D A Bennett711 Intraoperative aneurysms rupture during the predissection stage R A Beatty
Proceedings713 Association of British Neurologists, Hammersmith Hospital, London, 27-29 October 1988
Miscellaneous721 Matters arising721 Book reviews724 Notices
No 9 SEPTEMBER 1990 Editorial725 The brain in schizophrenia M A Ron, I Harvey
Papers727 Prosodic comprehension and expression in schizophrenia D Murphy, J Cutting731 Infarction in the territory of the medial branch of the posterior inferior cerebellar artery P Amarenco, E Roullet,
M Hommel, P Chaine, R Marteau736 Microneurography in relation to intraneural topography: somatotopic organisation of median nerve fascicles in
humans R G Hallin745 Transcranial electrical motor evoked potentials as a prognostic indicator for motor recovery in stroke patients
M Dominkus, W Grisold, V Jelinek749 Parkinsonian tremor loses its alternating aspect during non-REM sleep and is inhibited by REM sleep
J JM Askenasy,M D Yahr754 The effects of cyproheptadine on locomotion and on spasticity in patients with spinal cord injuries M Wainberg,
H Barbeau, S Gauthier764 Motor unit discharge characteristics and short term synchrony in paraplegic humans N J Davey, P H Ellaway,
C L Friedland, D J Short770 Magnetic and electrical stimulation of cervical motor roots: technique, site and mechanisms of excitation
U D Schmid, G Walker, C W Hess, J Schmid778 Eosinophilic meningitis: cause of a chronic pain syndrome P D Clouston, A J Corbett, D S Pryor, R Garrick782 Rigid spine syndrome with respiratory failure H Morita, K Kondo, K Hoshino, K Maruyama, N Yanagisawa785 Learning a unimanual skill by partial ccrnmissurotomy patients Y P Chen, R Campbell, J C Marshall,
D W Zaidel789 Involvement of the central nervous system in chronic inflammatory demyelinating polyneuropathy: a clinical,
electrophysiological and magnetic resonance imaging study I E C Ormerod,HM Waddy, A G Kermode,NM F Murray, P K Thomas
Short reports794 Cranial magnetic resonance imaging in chronic demyelinating polyneuropathy S H B Hawke, J M Hallinan,
J G McLeod797 Paramedian thalamic and midbrain infarcts associated with palilalia Y Yasuda, I Akiguchi,M Ino, H Nabatabe,
M Kameyama800 Sulpiride in tardive dyskinesia M Schwartz, L Moguillansky, G Lanyi, B Sharf
Letters803 Ferritin in the cerebrospinal fluid of patients with Parkinson's disease H S Pall, S Brailsford, A C Williams,
J Lunec, D R Blake803 The effects of repeated administration of a long acting TRH analogue (RX77368), on TSH, T4, T, and prolactin in
patients with motor neuron disease D J A Eckland, H Modarres-Sadeghi, S L Lightman, R J Guiloff804 Carotid dissection: a new false localising sign D C Hess, K D Sethi, F T Nichols805 Pure optic ataxia associated with a right parieto-occipital tumour S Ando, K Moritake806 Palatal myoclonus successfully treated with clonazepam A M 0 Bakheit, P 0 Behan806 Body building and rhabdomyolysis C Doriguzzi, L Palmucci, T Mongini
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Proceedings808 Association of British Neurologists and the Society of British Neurological Surgeons, Bristol, 4-6 April 1990
Miscellaneous818 Matters arising820 Book reviews
No 10 OCTOBER 1990 Editorial821 Risk factors for multiple sclerosis: race or place? Alastair Compston
Papers824 The frequency, causes and timing of death within 30 days of a first stroke: the Oxfordshire Community Stroke
Project J Bamford,M Dennis, P Sandercock, J Burn, C Warlow830 The natural history of non-arteritic anterior ischaemic optic neuropathy G V Sawle, C B James, R W Ross Russell834 Syndromes of transient amnesia: towards a classification. A study of 153 cases J R Hodges, C P Warlow844 Effect of nicardipine on somatosensory evoked potentials in patients with acute cerebral infarction L Yao, D Ding847 Insulin protects cognitive function in experimental stroke A J Strong, J E Fairfield, E Monteiro,M Kirby,
A R Hogg,M Snape, L Ross-Field854 Platelet monoamine oxidase B activity in Parkinsonian patients U Bonuccelli, P Piccini, P Del Dotto,
G M Pacifici, G U Corsini, A Muratorio856 Changes in the basal dendrites of cortical pyramidal cells from alcoholic patients-a quantitative Golgi study
C Harper, D Corbett862 Temporal movement control in patients with Parkinson's disease N Teasdale, J Phillips, G E Stelmach869 Specificity of affective and autonomic symptoms of depression in Parkinson's disease S E Starkstein, T J Preziosi,
A W Forrester, R G Robinson874 Neurophysiological observations on corticospinal projections to the upper limb in subjects with Rett syndrome
J A Eyre, A M Kerr, S Miller,M C O'Sullivan, V Ramesh880 Motor units in incomplete spinal cord injury: electrical activity, contractile properties and the effects of biofeedback
R B Stein, B S Brucker, D R Ayyar886 A clinico-pathological and follow up study of 10 cases of essential type II cryoglobulinaemic neuropathy
G Cavaletti, M G Petruccioli, V Crespi, P Pioltelli, P Marmiroli, G Tredici890 Visual evoked potential monitoring of optic nerve function during.surgery G F A Harding, J D P Bland,
V H Smith896 Determination of ventricular fluid outflow resistance in patients with ventriculomegaly T Lundar, H Nornes899 Do nurses or doctors have an increased risk of developing multiple sclerosis? G Dean, R Gray903 Multiple sclerosis in Australia and New Zealand: are the determinants genetic or environmental? D H Miller,
S R Hammond, J G McLeod, G Purdie, D C G Skegg906 Multiple sclerosis among United Kingdom-born children of immigrants from the Indian subcontinent, Africa and
the West Indies M Elian, S Nightingale, G Dean
Short reports912 Assessment of pupillary light reflex latency and darkness adapted pupil size in control subjects and in diabetic
patients with and without cardiovascular autonomic neuropathy P Lanting, J E Bos, J Aartsen, L Schuman,J Reichert- Thoen, J J Heimans
915 Neuropsychological profile linked to low dopamine: in Alzheimer's disease, major depression, and Parkinson'sdisease N Wolfe, D I Katz, M L Albert, A Almozlino, R Durso,M C Smith, L Volicer
918 Fulminant monophasic multiple sclerosis, Marburg's type M D Johnson, P Lavin, W 0 Whetsell Jr922 A case of amnesia after excision of the septum pellucidum A Berti, C Arienta, C Papagno
Letters925 Unilateral proptosis secondary to partially thrombosed giant carotid ophthalmic artery aneurysm R K Gupta,
V S Mehta, N K Misra926 Pituitary abscess. A case with recurrent aseptic meningitis D Guillaume, A Stevenaert, T Grisar, P Doyen,
M Reznik926 Transient global amnesia following ingestion of chloroquine P Cras, J-J Martin927 Iliac aneurysms J L A Eekhof, B J J Ansink, G Davies927 "Disconnected" integral ventriculo-peritoneal shunt systems J Walker, R CM Cook, R E Cudmore
Miscelianeous928 Book reviews928 Short Notices
No 11 NOVEMBER 1990 Editorial929 Non Alzheimer's disease forms of cerebral atrophy D Neary
Papers932 Early-onset dementia and extrapyramidal disease: clinicopathological variant of Gerstmann-Straussler-Scheinker
or Alzheimer's disease? J Hart Jr, B Gordon935 Touch and surgical division of the anterior quadrant of the spinal cord P W Nathan940 Diagnostic value of anti-neuronal antibodies for paraneoplastic disorders of the nervous system J WB Moll,
S C Henzen-Logmans, T A W Splinter, M E L van der Burg, Ch J Vecht944 Comparative efficacy and safety of intravenous and oral administration of a TRH analogue (RX77368) in motor
neuron disease H Modarres-Sadeghi, R J Guiloff948 Diurnal differences in response to oral levodopa J P Frankel, Z Pirtosek, P A Kempster, M Bovingdon, R Webster,
A J Lees, G M Stern
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951 Vitamin B12 and folate concentrations in serum and cerebrospinal fluid of neurological patients with specialreference to multiple sclerosis and dementia T Q Nijst, R A Wevers, H C Schoonderwaldt, 0 R Hommes,A F J de Haan
955 Electrophysiology of motor pathways for sphincter control in multiple sclerosis S E Mathers, D A Ingram,M Swash
961 Clinical diagnosis of Binswanger's disease D A Bennett, R S Wilson, D W Gilley, J H Fox966 A simple method to improve the accuracy of non-invasive ultrasound in selecting TIA patients for cerebral
angiography P Humphrey, P Sandercock, J Slattery972 The accuracy of predictions about progress of patients on a stroke unit N B Lincoln, JM Jackson, J A Edmans,
M F Walker, VM Farrow, A Latham, K Coombes976 Spectral analysis of tremor: understanding the results M Gresty, D Buckwell982 Lumbosacral evoked potentials and vesicourethral function in patients with chronic suprasacral spinal cord injury
M G Lucas, D G Thomas987 Slowly progressive aphasia: three cases with language, memory, CT and PET data D Kempler, E J Metter,
WH Riege, C A Jackson, D F Benson, WR Hanson994 Shy-Drager syndrome. Effect of fludrocortisone and L-threo-3,4-dihydroxyphenylserine on the blood pressure and
regional cerebral blood flow S Matsubara, Y Sawa, H Yokoji, M Takamori998 Contracturing granulomatous myositis: a separate entity N J Simmonds, B I Hoffbrand1001 Multiple spinal epidural metastases; an unexpectedly frequent finding J J van der Sande, R Kroger, W Boogerd
Short reports1004 Comparison of motor response to apomorphine and levodopa in Parkinson's disease P A Kempster, J P Frankel,
G M Stern, A J Lees1008 Evaluation of vigabatrin as an add-on drug in the management of severe epilepsy J W A S Sander,
P C Trevisol-Bittencourt, Y M Hart, S D Shorvon1011 Neuropsychological deficits in myotonic muscular dystrophy P Malloy, S K Mishra, S H Adler
Letters1014 A case of Pourfour Du Petit syndrome following parotidectomy P Byrne, C Clough1014 Hypothermia in a mesodiencephalic haematoma G Gaymard, H Cambon, D Dormont, A Richard, C Derouesne1015 Intranasal apomorphine: a new treatment in Parkinson's disease R Kapoor, N Turjanski, J Frankel, B Kleedorfer,
A Lees, G Stern, M Bovingdon, R Webster1015 Somatostatin in cerebrospinal fluid after generalised convulsions or cerebral infarction in humans H Cramer,
KM Heitzelmann1016 Autoscopy in hemianopic field R Bhaskaran, A Kumar, P C K K Nayar1017 Reoperation related to graft complication following anterior cervical fusion A B Jamjoom, J N Rawlinson,
J N Kirkpatrick
Miscellaneous1017 Matters arising1018 Book reviews
No 12 DECEMBER 1990 Editorial1021 Spinal Surgery Robin Johnston
Papers1024 Life events and difficulties preceding stroke A House,M Dennis, L Mogridge, K Hawton, C Warlow1029 Transient ischaemic attacks in young patients: a thromboembolic or migrainous manifestation? A 10 year follow up
study of 46 patients B Holt Larsen, P Soelberg Sorensen, J Marquardsen1034 Idiopathic and symptomatic trigeminal pain G Cruccu,M Leandri,M Feliciani, M Manfredi1043 Clinical features and associations of 560 cases of motor neuron disease TM Li, E Alberman, M Swash1046 Progressive degeneration of the right temporal lobe studied with positron emission tomography P J Tyrrell,
E K Warrington, R S J Frackowiak,MN Rossor1051 Vigabatrin: rational treatment for chronic epilepsy H A Ring, A J Heller, I N Farr, EH Reynolds1056 Symptomatic polyneuropathy in human immunodeficiency virus antibody seropositive men with and without
immune deficiency: a comparative electrophysiological study T Smith, J Jakobsen, J Gaub, W Trojaborg1060 Correlation between essential tremor and migraine headache N Biary, W Koller, P Langenberg1063 Neuronal ceroid-lipofuscinosis: preferential metabolic alterations in thalamus and posterior association cortex
demonstrated by PET A G De Volder, S Cirelli, Th de Barsy, JM Brucher, A Bol, Ch Michel, A M Goffinet1068 Cyclosporin-associated akinetic mutism and extrapyramidal syndrome after liver transplantation G L A Bird,
J Meadows, J Goka, R Polson, Roger Williams1072 Digital subtraction cisternography: a new approach to fistula localisation in cerebrospinal fluid rhinorrhoea
J V Byrne, C E Ingram, D Mac Vicar, F M Sullivan, D Uttley1076 Cauda equina syndrome associated with multiple lumbar arachnoid cysts in ankylosing spondylitis: improvement
following surgical therapy P J Shaw, D A Allcutt, D Bates, P J Crawford1080 Grading white matter lesions on CT and MRI: a simple scale J C van Swieten, A Hijdra, P J Koudstaal,
J van Gijn1084 Paraneoplastic limbic encephalitis: clinico-pathological correlations A M 0 Bakheit, P G E Kennedy, P 0 Behan1089 Differential impairment of semantic and episodic memory in Alzheimer's and Huntington's diseases: a controlled
prospective study John R Hodges, David P Salmon, Nelson Butters1096 Cerebrospinal fluid S-adenosylmethionine in depression and dementia: effects of treatment with parenteral and oral
S-adenosylmethionine T Bottliglieri, P Godfrey, T Flynn,M W P Carney, B K Toone, E H ReynoldsShort reports
1099 Multiple system degeneration with glutamate dehydrogenase deficiency: pathology and biochemistryS Chokroverty, W Nicklas, D C Miller, J Goldberg, J Choe, C Banner, J Thomas, R Duvoisin
1102 Hypothalamic obesity due to hydrocephalus caused by aqueductal stenosis N Suzuki,M Shinonaga, K Hirata,S Inoue, T Kuwabara
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Letters1104 "Alice in Wonderland" syndrome and infectious mononucleosis in children E Lahat, C Eshel, A Arlazoroff1104 Infarct in the territory of the medial branch of the pica C Masson, F Cheron1105 Efficacy of sublingual apomorphine in Parkinson's disease F Durif, D Deffond,M Tournilhac1105 CSF somatostatin-like immunoreactivity in dementia of Parkinson's disease W Poewe, T Benke, E Karamat,
L Schelosky,M Wagner1106 Multifocal astrocytoma presenting as action myoclonus P St J Trend,MM Pires, C J Earl1107 Cryptococcal granuloma of the brain C Keohane, R J Galvin, T F Buckley1108 A simple method for localisation and removal of small subcortical brain tumours E Fiumara, C de Grandi,
M Ferrara, C Corona, V D'Angelo,M Collice1109 Mononeuropathy associated with hyperthyroidism S Ijichi, N Ijichi, K Niina,M Tara, P Nakamura, S Izumo,
M Osame1110 MRI of thoracic cord in tropical spastic paraparesis A G Kermode, R Rudge, A J Thompson, E P G H du Boulay,
W I McDonald
Miscellaneous1112 Matters arising Book reviews * Notices1117 Listi of Assessors1119 List of Reviewers1120 Index to volume 53
Contents 1990
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