Neoplasia Introduction . By DR.HALA BADAWI LECTURER OF PATHOLOGY . Neoplasia. Characteristics . Gross picture. BENIGN. MALIGNANT. Not capsulated Areas of necrosis and haemorhage In solid organs : fixed irregular mass with ill defined borders - PowerPoint PPT Presentation
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Neoplasia Introduction
ByDR.HALA BADAWILECTURER OF PATHOLOGY
Neoplasia Introduction NeoplasiaCharacteristics
BENIGNMALIGNANTGross picture Spherical or ovoid in shape Mostly
capsulated No haemorrhage or necrosis Not capsulated Areas of
necrosis and haemorhage In solid organs: fixed irregular mass with
ill defined bordersIn body surfaces: Polypoid (fungating),
infiltrating or ulcerative
3NeoplasiaCharacteristics
BENIGNMALIGNANTMicroscopic pictureCytological Features
Cytological atypia (anaplasia) Change in cellular
morphologyCellular polymorphism, nuclear hyperchromatism, mitoses
& tumour giant cells Change in cellular pattern (Loss of
polarity)Cells like the original cell Microscopic Features
(ANAPLASIA) PleomorphismHyperchromatic nucleiMultiple large
nucleoliHigh N/C ratioHigh mitotic rateAbnormal mitosis Tumor giant
cells
