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Supplementary Figure 2. High magnification of the white matter (WM) located near the C2 crossroad area in a very preterm case (VPT) (25 pcw) with noncystic periventricular white matter injury (a, c, e, g, i) and a control case (26 pcw) (b, d, f, h, j). a,b: hemalun-phloxine staining (HPS). c, d: GFAP+ astrocytes (brown) and Iba1+ microglial cells (black). e, f: CD34+ vessel walls (brown) - monocarboxylate transporter 1+ (MCT1, black). g, h: Iba1 immunostaining showing increased numbers of reactive microglia-macrophages. i, j: immunolabeling for the axonal filament SMI31. Scale bar: 50 µm.

NEN_71_3_2012_01_05_VERNEY_200838_SDC2

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Supplementary Figure 2. High magnification of the white matter (WM) located near the C2 crossroad area in a very preterm case (VPT) (25 pcw) with noncystic periventricular white matter injury (a, c, e, g, i) and a control case (26 pcw) (b, d, f, h, j). a,b: hemalun-phloxine staining (HPS). c, d: GFAP+ astrocytes (brown) and Iba1+ microglial cells (black). e, f: CD34+ vessel walls (brown) - monocarboxylate transporter 1+ (MCT1, black). g, h: Iba1 immunostaining showing increased numbers of reactive microglia-macrophages. i, j: immunolabeling for the axonal filament SMI31. Scale bar: 50 µm.