Nature Creates We Refine Feed enzyme development Enzymes for
poultry and piglets feeds in Finland Biological silage
preservatives International business activities, silage
preservatives Export of Progut 1980ies Suomen Rehu has long
experience from functional feed ingredients Special feeds for
better rumen function International business activities, enzymes
Export to Scandinavia, Baltic countries, Russia, Taiwan Development
of antibiotic replacement in piglet feeds Progut yeast hydrolysate
Progut Rumen Progres Expansion of product range and export areas
1994 1999
Slide 3
Nature Creates We Refine Drivers and targets for feed and
ingredient development Production performance Animal health and
wellbeing Food quality and safety Environment Feeding costs
Antimicrobial resistance Animal welfare Production structure and
disease challenge Animal health and productivity starts in the gut
Utilization of industry side-streams
Slide 4
Nature Creates We Refine Screening tube research model Product
with desired functional properties Animal models and clinical
trials Simulators Test tubes Compounds from industry side-streams
Purpose, potential functions Availability, high volume, low price
Development of new methods
Slide 5
Nature Creates We Refine Development of Progut and Progres Rat
trials, performance and challenge trials Simu- lators Bacterial
growth inhibition and attachment assays Compounds to prevent E.coli
growth and stimulate immunity Blood, larch tree extract Peat
Brewery yeast waste Prevention of weaning diarrhea Prevention of
Gram+ pathogens Compounds to prevent Gram + growth and improve feed
efficiency Bark, knot-wood, tall oil other forest industry side
streams
Slide 6
Nature Creates We Refine A naturally occurring product from
coniferous forests which is extracted as a by-product of the pulp
manufacturing industry. The final refined product contains modified
tall oil fatty acids and standardized amount of resin acids. We
have develop this by-product into a specific concentration of resin
acids and tall oil fatty acids which have never before been used in
animal feeds Potential To improve efficiency of meat production
systems To reduce reliance on antibiotics Patent protected product
and applications.
Slide 7
Nature Creates We Refine Market Need Global meat production
will need to double by 2050 to cater for a rising population (FAO).
Need for improved feed efficiency and environmental sustainability
As production systems intensify, so does the pressure from
pathogenic bacteria. Reliance on antibiotic solutions is
unsustainable. Demand for effective natural solutions. The global
feed additive market for natural additives is currently 3bn and
rising. The need of antibiotic free meat production is consumer
driven. Antimicrobial resistance is one of our most serious health
threats The Lancet 2013 Half of the raw chicken meat carried
antibiotic-resistant superbug bacteria in USA Reuters
19.12.2013
Slide 8
Nature Creates We Refine Rosin, containing resin acids, has
been used in traditional medicine in Finland for centuries The
antimicrobial and antiprotozoal effects of resin acids are proven
by scientific trials (Ali et al. 2012, Sipponen A. 2013) We are the
first to develop the resin acids into a form that optimizes their
efficacy in animal feeding (patents) 1. Naturally
Slide 9
Nature Creates We Refine 2 Active: ProgRes supports the health
and productivity of animals In trials Progres has: Prevented the
growth of pathogenic Gram + bacteria Such as clostridium
perfringens and streptococcus suis Reduced the development of
necrotis enteritis Modified the composition of intestinal
microflora to beneficial direction Lead to decreased mortality,
better health and growth performance in broilers and turkeys
Slide 10
Nature Creates We Refine The effect of ProgRes on the growth of
different pathogenic Gram+ bacteria (Alimetrics 2014)
Slide 11
Nature Creates We Refine NE challenge trial with broiler chicks
Alimetrics 2012 Wheat based starter diet without coccidiostat
Progres inclusion at 0, 0.1, 0.5, 1 and 3 kg/tn 1-day-old Male Ross
508 broiler chickens 6 chickens/pen, 8 pens/diet
Slide 12
Nature Creates We Refine Progres at high dose decreased
mortality due to necrotis enteritis Alimetrics 2012 **, p < 0.01
(H. Kettunen et al. 2015 J. Applied Animal Sci)
Slide 13
Nature Creates We Refine Challenge trial in broilers at
Schothorst Feed Research 2014 96 male broilers per treatment (6 *16
birds) Eimeria maxima challenge at day 9, Clostridium perfringens
challenge at day 14 Progres additions 0, 1, 2 and 3 kg per ton The
challenge caused a sub-clinical infection without affecting
mortality
Slide 14
Nature Creates We Refine Broiler trial at Schothorst Feed
Research 2014 a,b p < 0.05
Nature Creates We Refine Progres Trials in broilers 2014 CC +
feedsDifference in end weight to the control g Difference in FCR, g
France+ 41+-0 UK+ 32-60 Denmark+ 10-10 The Netherlands+ 49-20 CC
feeds France+ 118+-0 The Netherlands+ 195+- 0 Finland+ 226-60
Slide 17
Nature Creates We Refine Other potential applications Trials
with calves, piglets, fish and ruminants are going on Other feed
applications (other poultry species, rabbits, sheep, pets etc.)
Non-feed applications
Slide 18
Nature Creates We Refine Thank you for your interest!