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CURRICULUM VITAE Oscar A. de Leon-Casasola Revision Date: 10-14-08 Department of Anesthesiology and Critical Care Medicine Roswell Park Cancer Institute Buffalo, New York 14263 Telephone: 716-845-8804 Telecopier: 716-845-8518 e-mail: [email protected] 5100 Rockledge Drive Clarence, NY 14031 Telephone: +1-716-759-6197 Education: 1982 M.D. Universidad de San Carlos de Guatemala, Guatemala City, Guatemala 1976 Bachiller Bachelor in Arts with specialty in Piano National Conservatory of Music Guatemala City, Guatemala Postdoctoral Training: Internship and Residencies: 1981-1982 Rotating Internship Military Hospital, Guatemala 1982-1983 Senior Resident, General Surgery Military Hospital, Guatemala 1

My Patient With Rectal Cancer Does Not Have Pain ...My

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CURRICULUM VITAE

Oscar A. de Leon-Casasola

Revision Date: 10-14-08

Department of Anesthesiologyand Critical Care MedicineRoswell Park Cancer InstituteBuffalo, New York 14263Telephone: 716-845-8804Telecopier: 716-845-8518e-mail: [email protected]

5100 Rockledge DriveClarence, NY 14031

Telephone: +1-716-759-6197

Education:

1982 M.D. Universidad de San Carlos de Guatemala, Guatemala City, Guatemala

1976 Bachiller Bachelor in Arts with specialty in Piano National Conservatory of Music Guatemala City, Guatemala

Postdoctoral Training:

Internship and Residencies:

1981-1982 Rotating Internship Military Hospital, Guatemala

1982-1983 Senior Resident, General Surgery Military Hospital, Guatemala

1984-1985 House Officer, General Surgery Cedars Medical Center, Miami

1985-1986 Intern in General Surgery State University of New York Downstate-Brooklyn, New York

1986-1987 Resident in General Surgery Critical Care Fellowship Track

State University of New York Downstate-Brooklyn, New York

1987-1989 Resident in Anesthesiology State University of New York, Buffalo

1989-1990 Chief Resident, Anesthesiology

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State University of New York, Buffalo

Licensure:

1984-1991 Oklahoma License Registration1988 Florida License Registration1989 Pennsylvania License Registration1990 New York License Registration

Board Certification:

1991 American Board of Anesthesiology #19247 1993 Critical Care Medicine #562

1994 Pain Medicine #5302003 Recertification in Pain Medicine #19247

Academic Appointments:

1987 - 1990 Clinical Assistant Instructor in Anesthesia, University at Buffalo 1990 - 1991 Instructor in Anesthesia, University at Buffalo 1991 - 1996 Assistant Professor in Anesthesia, University at Buffalo

1996 - 2001 Associate Professor in Anesthesia with Tenure, University at Buffalo

2001 Professor of Anesthesiology with Tenure, University at Buffalo2006 Professor of Oncology, Roswell Park Cancer Institute

Hospital Appointments:

1990 - Anesthesiologist, Roswell Park Cancer Institute, Buffalo, New York

1991 - 1993 Director of the Acute Pain Service, Roswell Park Cancer Institute, Buffalo, New York

1991 - 1993 Staff, Critical Care UnitRoswell Park Cancer Institute, Buffalo, New York

1993 - 1994 Director, Surgical Intensive Care Unit Roswell Park Cancer Institute, Buffalo, New York

1994 - 1998 Chief, Critical Care Medicine Roswell Park Cancer Institute, Buffalo, New York

1998 - Director, Anesthesia ResearchRoswell Park Cancer Institute

1999 - Chief, Pain Medicine and Symptom ManagementRoswell Park Cancer Institute

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University of Buffalo, Department of Anesthesia Appointments:

2001 - Vice-Chairman for Clinical Affairs

University at Buffalo, School of Medicine and Biomedical Sciences Responsabilities

1992 - 1994 Representative to the Faculty Council of the School of Medicine

1992 - 1993 Alternate Senator, University Faculty Senate. 1993 - 1994 Search Committee for Chairman of the

Department of Anesthesiology of Millard Fillmore Hospital

1993 - 1994 Appointments, Promotions, Tenure and Privileges Committee

1999 - 2001 Representative to the Faculty Council of the School of Medicine

University at Buffalo, Department of Anesthesiology Committee Responsabilities:

1990 - 1994 Education Committee1993 - Research Committee1993 - Critical Care Committee1995 - Appointments, Promotions, Tenure and

Privileges Committee2000 - Academic Anesthesiology Advisory Council2006 - Executive Committee

University at Buffalo, Department of Anesthesiology Teaching Responsabilities:

1991 - Faculty lecturer in Resident Seminars, Department of Anesthesiology State University of New York at Buffalo School of Medicine, Buffalo, New York

1993 - Faculty lecturer in Graduate Students Seminars, Pathophysiology Course Roswell Park Cancer Institute

1998 - Faculty lecturer in Medical Students Selectives for Pain Management

1999 - Director, Pain Fellowship Program

Hospital Service Responsibilities:

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1991 - 2000 Critical Care Unit Team, Roswell Park Cancer Institute, Buffalo, New York

1991 - Pain Service Team, Roswell Park Cancer Institute, Buffalo, New York

Awards and Honors:

1989 - 1990 Chairman's Award, outstanding resident Department of Anesthesiology

SUNY at Buffalo.1989 - 1990 Administrative Chief Resident

Department of Anesthesiology SUNY at Buffalo.

1991 Award of Excellence, abstract presented at the Second Annual Upstate Academic Anesthesia Conference. Rochester, NY.

1992 SUNY at Buffalo Anesthesia Residents' Teaching Award in Recognition to Excellence in the Art of Academic and Clinical Anesthesia. 1992 Best abstract presented, Symposium on Visceral Pain, Ibero-American Congress of Anesthesiology. Barcelona, Spain.

1992 First Place, abstract presented at the Third Annual Upstate Academic Anesthesia Conference. Rochester, NY.

1995 First Place, abstract presented at the Sixth Annual Upstate Academic Anesthesia Conference. Rochester, NY.

1996 Western New York Business First “40 Under Forty” award.1999 Member Honoris Causa, Colombian Society of Anesthesiology2000 Annual Outstanding Physician Partner Award, Postgraduate

Institute for Medicine2003 Top Doctor – Top Pain Clinic

Good Housekeeping Magazine: Top Pain Clinics in the Country. May 2003

2004 Chair, Scientific Committee for the Fall Meeting – ASRA and Pain Management

2005 America’s Top Doctors. Castle Connolly’s Guide to Medical Specialists

2005 List, Empire Who’s Who Among Executives and Professionals in Medicine & Healthcare (“Honors Edition”)

2006 100 “Top Docs in Buffalo” Buffalo Spree Magazine, Jan-Feb 2006 (http://www.buffalospree.com/spree/archives/2006_0102/010206TopDocsList.html)

2006 M/Pfizer Visiting Professorship in Pain Medicine Award Recipient at Wayne State University, Detroit, MI

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2006 Consumers’ Research Council of America, “Guide to America’s Top Physicians”

2006 America’s Top Doctors for Cancer. Castle Connolly’s Guide to Medical Specialists

New York’s Top Doctor. Castle Connolly’s Guide to Medical Specialists

2007 List, Leading Health Professionals of the World (International Biographical Centre, Cambridge, England)

2007 List, Who’s Who Among Executives and Professionals in Medicine & Healthcare (“Honors Edition”)

2007 Pfizer Award Visiting Professor at Wayne State University

2007 Best Doctors in America 2007-2008 database2007 Castle Connolly Medical list of America’s Top

Doctors for Cancer2007 European Society of Regional Anesthesia (ESRA)

Distinguished Service Award – Spain Meeting2008 Key Note Speaker: Wayne State University Annual

Symposium on Regional Anesthesia and Pain Medicine2008 Key Note Speaker: 50th Anniversary Meeting of the

Guatemalan Society of Anesthesiology2008 Castle Connolly Medical list of America’s Top

Doctors for Cancer

Visiting Professor Appointments:

1992 Department of Anesthesiology, Universidad Catolica, Cuenca, Ecuador

1993 Department of Anesthesiology, Virginia Mason Medical Center Seattle, Washington

1994 Department of Anesthesiology, University of Wisconsin-Madison Madison, Wisconsin

1994 Department of Anesthesiology, SUNY, Health Science Center Syracuse, New York

1994 Department of Anesthesiology, Hospital for Special Surgery, Cornell University New York, New York

1994 Department of Anesthesiology Mayo Clinic, Jacksonville, Florida

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1996 Department of Anesthesiology, St. Luke's - Roosevelt Hospital New York, New York

1996 Department of Anesthesiology, Loyola University Chicago Chicago, Illinois

1996 Department of General Surgery Naval Medical Center Portsmouth, Virginia

1996 Department of AnesthesiologyMD Anderson Cancer CenterHouston, Texas

1996 Department of AnesthesiologyUniversity of West VirginiaMorgantown, West Virginia

1997 Department of AnesthesiologyMayo ClinicJacksonville, FL

1997 Department of AnesthesiologyUniversity of WisconsinMadison, WI

1997 Department of AnesthesiologyHenry Ford Medical CenterDetroit, MI

1997 Department of AnesthesiologyVirginia Mason Medical CenterSeattle, WA

1997 Department of Anesthesiology and Critical Care MedicineDartmouth-Hitchcock Medical CenterLebanon, NH

1998 Department of Anesthesiology and Critical Care MedicineMayo ClinicJacksonville, Fl

1998 Department of Anesthesiology and Critical Care MedicineUniversity of New MexicoAlbuquerque, NM

1998 Department of Anesthesiology and Critical Care MedicineSunnybrook Health Science CentreToronto, Ontario, Canada

1999 Department of AnesthesiologyBaylor Medical CollegeHouston, Texas

1999 Department of Anesthesiology and Critical Care MedicineMD Anderson Medical Center

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Houston, Texas1999 Department of Anesthesiology and Pain Medicine

University of Kentucky, Chandler Medical CenterLexington, Kentucky

1999 Department of Anesthesiology and Critical Care MedicineRush UniversityChicago, Illinois

1999 Department of Anesthesiology and Critical Care Medicine University of Maryland Baltimore, Maryland

2000 Department of Anesthesiology and Critical Care MedicineDuke University Medical CenterDurham, North Carolina

2000 Department of Anesthesiology and Critical Care MedicineThe University of Texas, Southwestern Medical Center at DallasDallas, Texas

2000 Department of Anesthesiology and Critical Care MedicineUniversity of South FloridaTampa, FL

2000 Department of AnesthesiologyUniversity of West VirginiaMorgantown, West Virginia

2000 Department of AnesthesiologyUniversity of VermontBurlington, Vermont

2000 Department of AnesthesiologyThomas Jefferson UniversityPhiladelphia, PA

2000 Department of AnesthesiologyMCP-Hahneman UniversityPhiladelphia, PA

2001 Department of UrologySUNY at Syracuse, Upstate Medical CenterSyracuse, NY

2001 Department of AnesthesiologyMayo Clinic JacksonvilleJacksonville, FL

2001 Department of AnesthesiologyUniversity of LouisianaShreveport, LA

2002 Department of AnesthesiologyLoma Linda UniversityLoma Linda, CA

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2002 Department of Anesthesiology and Pain MedicineUniversity of Kentucky, Chandler Medical CenterLexington, Kentucky

2002 Department of AnesthesiologyWayne State UniversityDetroit, Michigan

2002 Department of AnesthesiologyUniversity of LouisianaShreveport, LA

2002 Section of Pain MedicineStrong Memorial HospitalRochester, NY

2002 Department of MedicineWilliam Beaumont HospitalRoyal Oak, MI

2002 Department of AnesthesiologyWest Virginia UniversityMorgantown, WV

2003 Department of AnesthesiologyUniversity of Southern California at Los AngelesLos Angeles, CA

2003 Department of AnesthesiologyWayne State UniversityDetroit, MI

2003 Department of AnesthesiologyUMDNJ UniversityNew Brunswick, NJ

2003 Department of Medical OncologyAlleghany HospitalPittsburgh, PA

2003 Department of Pain and Palliative CareSloan Kettering Memorial HospitalNew York, NY

2003 Department of Pain MedicineCleveland Clinic FoundationCleveland, OH

2003 Department of AnesthesiologyUniversity of South FloridaTampa, FL

2003 Department of Internal MedicineMt. Vernon HospitalMt. Vernon, NY

2003 Department of SurgeryOur Lady of Mercy Medical Center

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Bronx, NY2004 Department of Anesthesiology

Brigham and Women’s HospitalBoston, Massachusetts

2004 Department of SurgeryUniversity of Rochester, Strong Memorial HospitalRochester, NY

2004 Department of AnesthesiologyUniversity of Miami, Jackson Memorial HospitalMiami, Fl

2004 Department of AnesthesiologyTufts University Boston, Massachusetts

2005 Department of AnesthesiologyIowa UniversityIowa City, Iowa

2005 Department of AnesthesiologyHenry Ford HospitalDetroit, MI

2005 Department of AnesthesiologyHarpor Hospital, Wayne State UniversityDetroit, MI

2005 Department of AnesthesiologyBowman Gray UniversityWinston-Salem, NC

2005 Department of Anesthesiology MD Anderson Cancer CenterHouston, TX

2006 Department of AnesthesiologyOhio State UniversityColombus, OH

2006 Division of Pain MedicineCornell UniversityNew York, NY

2006 Department of AnesthesiologyBeth Israel-Deaconess Medical Center Harvard Medical SchoolBoston, Massachusetts

2006 Department of AnesthesiologyHenry Ford Medical CenterDetroit, MI

2006 Department of RheumathologyAlbert Einstein Hospital, Yashida UniversityNew York NY

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2006 Department of AnesthesiologyHarpor Hospital, Wayne State UniversityDetroit, MI

2007 Department of Anesthesiology and Pain MedicineWayne State UniversityDetroit, MI

2007 Department of AnesthesiologyUniversity of Kentucky at LouisvilleLouisville, KY

2007 Department of AnesthesiologyBaylor Medical CollegeHouston, TX

2008 Department of AnesthesiologyBoston UniversityBoston, MA

2008 Department of RheumathologyAlbert Einstein Medical SchoolBronx, NY

2008 Department of Physical Medicine and RehabilitationMontfort Medical CenterBronx, NY

Editorial Appointments

1994 - 1996 Assistant Editor, American Society of Regional Anesthesia Newsletter

1994 - 2004 Board of Consulting Editors, Regional Anesthesia1994 - 2000 Associate Editor, Revista Latinoamericana de Dolor

(Latin American Journal of Pain)1995 - Associate Editor, Revista Argentina de Anestesiologia

(Argentinian Journal of Anesthesiology)1995 - 1999 Assistant Section Editor, The Pain Journal Club Journal1995 - 2000 Editorial Board, Techniques in Regional Anesthesia and Pain

Management Journal1997 - Editorial Board, International Journal of Acute Pain1997 - Associate Editor, The Journal of the Spanish Society of Pain1999 - 2001 Editor, Current Review of Pain1999 - 2000 Member, Editorial Board, Clinical Journal of Pain1999 - Member, Editorial Board, International Monitor on Regional

Anaesthesia and Pain Therapy (Journal of the European Society of Regional Anesthesia and Pain Therapy)

2000 - Editor-in-Chief, Techniques in Regional Anesthesia and Pain Management

2000 - 2007 Associate Editor, The Clinical Journal of Pain

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2003 - 2004 Member, Editorial Board, Seminars in Pain Medicine

2004 - International Board Editor, Revista Mexicana de Anestesiologia (Mexican Journal of Anesthesiology)

2004 - Editorial Board, Seminars in Pain Medicine

Guest Reviewer:

Journals:

1993 - 1994 Regional Anesthesia 1994 - Anesthesiology1994 - Journal of Clinical Anesthesia1995 - Anesthesia and Analgesia

Invited Lectures:

NY State

1990 First Annual Tri-City Anesthesiology Conference, Rochester, New York; "A Comparison of 2-Chloroprocaine infusion

with Intermittent Bolus Injections of Bupivacaine or 2-Chloroprocaine For Epidural Anesthesia in Cesarean Delivery

1990 Roswell Park Cancer Institute, Buffalo, New York; Annual Conference on Advanced Issues in Critical Care Nursing, "Pain Management in the critically ill patient"

1990 Annual Meeting of the New York Association of Nurse Anesthetists, Buffalo, New York; "Recent advances in Spinal and Epidural

Anesthesia-Analgesia"1991 Mercy Hospital, Buffalo, New York;

Surgical Grand Rounds; "Improving outcome in high risk surgical patients with epidural anesthesia and analgesia"

1991 Brooks Memorial Hospital, Dunkirk, NY "Perioperative management of cancer patients with coronary artery disease"

1991 Critical Care Rounds, SUNY-Buffalo

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"Improving outcome in high risk surgical patients, postoperative management"

1991 Genesee Hospital, Rochester, NY Anesthesia Grand Rounds; "What is new in Neuromuscular Blocking and Reversal Agents"

1991 City Wide Anesthesia Conference, Binghamton General, Wilson and Lordes Hospitals, Binghamton, NY "Current Applications of Beta-Blockade Intraoperatively and in the Intensiv Care Unit"

1991 City Wide Anesthesia Conference, Arnot-Ogden and St. Joseph Hospitals Elmira, NY "Current Applications of Beta-Blockade in the Intra- and Postoperative Periods"

1991 Albany Medical College, Department of Anesthesiology Grand Rounds, Albany, NY "Inhibition of the Neuroendocrine response with Epidural Anesthesia and Analgesia”

1991 Albany Medical College, Department of Anesthesiology Residents Teaching Day, Albany, NY "Perioperative Management of Patients with Coronary Artery Disease Undergoing Non-Cardiac Surgery"

1991 Surgical Grand Rounds, SUNY-Buffalo, NY "Perioperative Use of Beta-Blockers. Outcome Studies"

1991 Roswell Park Cancer Institute, Annual Conference in Advanced Issues in Critical Care Nursing.

Buffalo, NY "Improving Outcome in High Risk Surgical Patients with Epidural Anesthesia and Analgesia" "Pharmacological Basis for Colloid and Crystalloid Fluid Therapy"

1991 Postgraduate Assembly in Anesthesiology, Miniworkshop. New York, NY "Anesthesia for Carotid Endarterectomy. Monitoring and Preserving Cerebral and Cardiac Function"

1992 Erie County Medical Center, Anesthesia Dept Weekly Conference. Buffalo, NY

"Thoracic Epidural Anesthesia and Analgesia" 1992 South Buffalo Mercy Hospital, Anesthesia

Dept Weekly Conference. Buffalo, NY

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"Intraoperative Use of Beta-Blockers"1992 Sister's Hospital, Anesthesiology Dept.

Weekly Conference. Buffalo, NY "Perioperative Indications of Beta Blockade"

1992 Rochester General Hospital, Anesthesiology Department. Weekly Conference. Rochester, New York "What is New in Reversal of Neuromuscular Blockade"

1992 Departments of Anesthesiology and Surgery Grand Rounds, SUNY-Buffalo, "Current Advances in the Care of Critically Ill Surgical Patients:

Post Operative Myocardial Ischemia: Diagnosis Treatment and Influence in Outcome". Buffalo, New York

1992 Department of Surgery, Grand Rounds, Roswell Park Cancer Institute "Postoperative Myocardial Ischemia, Diagnosis, Treatment and Influence onOutcome".

Buffalo, NY1992 Roswell Park Cancer Institute, Oncology

Seminar Series. Total Management of the Chronic Pain Patients. "Management of Postoperative Pain in the Chronic Pain Patient". Buffalo, NY

1992 Children's Hospital of Buffalo, Pediatric Surgery and Anesthesia Grand Rounds. "Physiopathologic Basis for Acute Pain Control".

Buffalo, NY1992 Du Pont Pharmaceuticals Dinner Series

"Postoperative Myocardial Ischemia: Diagnosis, Treatment and Influence on Outcome".

Buffalo, NY1992 Sisters' Hospital of Buffalo

Anesthesia Grand Rounds. "Colloids vs Crystalloids". Buffalo, NY

1992 Erie County Medical Center, Anesthesia Weekly Conference.

"Improving Postoperative Outcome with Epidural Anesthesia and Analgesia". Buffalo, NY

1992 WAC Hospital, Medical-Surgical Grand Rounds. "Postoperative Myocardial Ischemia: Diagnosis, Treatment and Influence on Outcome”. Jamestown, NY

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1992 University of Buffalo Surgical Grand Rounds. "What is new in Improving Outcome of the

High Risk Surgical Patient". Buffalo, NY1993 Erie County Medical Center, Dept of

Anesthesiology Weekly Conference "Colloids vs Crystalloids". Buffalo, NY

1993 Buffalo General Hospital, Dept of Cardio-Thoracic Surgery Grand Rounds "Colloids vs Crystalloids". Buffalo, NY

1993 Roswell Park Cancer Institute, Dept of Surgical Oncology Grand Rounds "Perioperative Fluid Management of the Critically Ill".

Buffalo, NY1993 Erie County Medical Center, Department of Pharmacy.

"Perioperative Fluid Management"1993 Utica and Rome Anesthesia Association

"Perioperative Management of Patients with Heart Disease Undergoing Non-Cardiac Surgery".

Utica, NY1993 University of Rochester, Department of

Critical Care Medicine Grand Rounds "Fluid Optimization of the Critically Ill Patient”. Rochester, NY

1993 Buffalo General Hospital Anesthesia Grand "Does Regional Anesthesia and Analgesia Improve Clinical Outcome?". Buffalo,NY

1994 Roswell Park Cancer Institute, Department of Surgical Oncology Grand Rounds

"Hemodynamic Monitoring in the Critically Ill". Buffalo, NY

1994 Veterans Administration Medical Center, Department of Surgery Grand Rounds "Fluid Management of the Critically Ill". Buffalo, NY

1994 Millard Fillmore Hospital, Symposium inPain Management "Improving Surgical Outcome of High Risk Surgical Patients

with Epidural Anesthesia and Analgesia", Buffalo, NY1994 Millard Fillmore Hospital

Department of Surgery Rounds "Fluid Management of the Critically Ill". Buffalo, NY

1994 Buffalo General Hospital, Department of Surgery Rounds "Perioperative Fluid Management in the Critically Ill".

Buffalo, NY

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1994 Veterans Administration Hospital, Department of Anesthesiology Grand Rounds

"Pharmacokinetics of Intravenous Fluids used for Resuscitation: Clinical Implications".

Buffalo, NY 1994 Genesee Hospital, Department of Anesthesiology Grand Rounds

"Colloids vs Crystalloids in the Perioperative Period", Rochester, NY

1994 ASTRA Regional Anesthesia Workshop Complications of Regional Anesthesia Uniondale, NY

1994 St Mary's Hospital, Combined Surgical and Anesthesiology Grand Rounds.

"Preload Augmentation and Surgical Outcome. Differences Between Colloids and Crystalloids". Rochester, NY

1994 Rochester General Hospital. Department of Anesthesiology Grand Rounds.

"Epidural Anesthesia and Analgesia: Is There MoreBeyond Pain Control?".

Rochester, NY1994 Buffalo Surgical Society.

"Perioperative Fluid Management of High Risk Surgical Patients” Buffalo, NY

1994 Oncology Seminar Series. Roswell Park Pain Management Weekend "Epidural vs PCA: Is Either One Better for Postoperative Analgesia?"

1994 48th Postgraduate Assembly, NYSSA "Pain Management in Critical Care Patients" MINIWORKSHOP "The PACU Use of Epidural Local Anesthetics and Opioids"

PANEL: PAIN RELIEF IN THE PACU. Panel Chair: Joseph Seltzer, MD

1995 St. Joseph's Hospital. Department of Anesthesiology Grand Rounds. "How to Choose a Colloid for Perioperative Fluid Management" Syracuse, NY

1995 St. Joseph's Hospital. Department of Anesthesiology Grand Rounds.

"The Use of Epidural Local Anesthetics and Opioids forPostoperative Analgesia"

Syracuse, NY1995 ASRA Regional Refresher Course.

"Epidural Anesthesia and Analgesia for Thoracic and

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Abdominal Procedures" Workshop: "Cervical and Thoracic Epidural Techniques" Uniondale, New York

1995 New York Society of Anesthesiologist: 49th Post-Graduate Assembly.

"Pain Management in the Intensive Care Units" New York, New York

1996 New York Society of Anesthesiologists:50th Post-Graduate Assembly“Pain Managemtn in the Intensive Care Unit”New York, New York

1997 Roswell Park Cancer InstituteDepartment of Surgical Oncology Grand Rounds“Weaning from Mechanical Ventilation: Is It That Controversial?”Buffalo, New York

1997 Genesee HospitalDepartment of Anesthesiology Grand Rounds“Neurolytic Blocks of the Sympathetic Axis for Cancer PainManagement”Rochester, New York

1997 Veterans Administration HospitalDepartment of Anesthesiology Grand Rounds“Thoracic Epidural Anesthesia and Analgesia for Patients withCAD Undergoing non-Cardiac Surgery”

1997 New York State Society of Anesthesiologists51st Post-Graduate Assembly“Pain Management in the Intensive Care Unit”“Postoperative Myocardial Ischemia: Can PostoperativeManagement Improve Cardiac Outcome?”New York, New York

1998 Department of Gynecology-Oncology“Pitfalls in Hemodynamic Monitoring”Roswell Park Cancer Institute Buffalo, NY

1998 Eastern Pain Society Meeting“Current Advances in Diagnostic and Therapeutic Spinal

Injections”New York City, NY

1998 New York State Society of Anesthesiology, PGA Meeting“Preoperative Evaluation of Cardiac Patients for Thoracic

Surgery”Workshop: “Thoracic Epidural Anesthesia”New York City, NY

1999 The World Foundation for Pain Relief and Research Meeting

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Current Concepts in Acute, Chronic and Cancer Pain Management“Role of Regional Anesthesia Techniques: Their Efficacy and Outcome”New York City, NY

1999 The New York State Society of Anesthesiologist PGA Meeting“Postoperative Epidural Analgesia: Cardiac and Respiratory Benefits”“Epidural Techniques for Thoracic Surgery”

2000 Erie County Medical CenterGrand Rounds, AIDS service“Pain Management in Patients with AIDS”

2000 Erie County Medical CenterGrand Rounds, Department of MedicinePain Management for the Non-Pain Specialist

2000 Eastern Pain Society Meeting“Neurolysis of the Sympathetic Axis for Cancer Pain”New York, NY

2000 The New York State Society of Anesthesiologist PGA MeetingChair: Panel on Thoracic Anesthesia“Thoracic Epidural Anesthesia: The nuts and bolts”Workshop: “Epidural Techniques for Thoracic Surgery”New York, NY

2000 Department of Surgical Oncology “Meet the Professor Rounds”Cancer Pain Management: What is New?Roswell Park Cancer Institute, Buffalo, NY

2001 “Postoperative Pain Management”Department of Gynecology and ObstetricsUniversity at Buffalo, Buffalo, NY

2001 Eastern Pain Association Annual MeetingModerator: Visceral Pain PanelNew York, NY

2001 “Cancer Pain Management for a Non-Pain Practitioner”Department of MedicineUniversity at Buffalo, Buffalo, NY

2001 The New York State Society of Anesthesiologists PGA Meeting“Neurolytic Blocks for Cancer Pain”“What is New in Cancer Pain Management”PBLD: “Chronic Low Back Pain”Focus Session: Case Presentations in Thoracic AnesthesiaChair: Panel on 5th Vital SignThoracic Workshop: Thoracic Epidural Anesthesia and AnalgesiaNew York, NY

2002 The Eastern Pain Association Annual Meeting“Optimizing Intraspinal Therapy in Cancer Patients”

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New York, NY2002 The New York State Society of Anesthesiologists PGA Meeting

“Is Epidural Anesthesia Better Than General to Improve Outcome”“Perioperative Management of Patients with Opiate Tolerance”“Evaluation and Treatment of Patients with Low Back Pain”“Thoracic Epidural Workshop”

2002 New York State Society of Regional Anesthesia“Multimodal Therapy to Improve Perioperative

Outcome in Surgical Patients”2003 The New York State Society of Anesthesiologists PGA Meeting

PBLD: “Chronic Low Back Pain”Thoracic Workshop: Thoracic Epidural Anesthesia and AnalgesiaNew York, NY

2004 The New York State Society of Anesthesiologists PGA MeetingPBLD: “Chronic Low Back Pain”Thoracic Workshop: Thoracic Epidural Anesthesia and AnalgesiaNew York, NY

2005 The New York State Society of Anesthesiologists PGA MeetingConventional and Unconventional Pain Techniques Panel:“Sophistry in Pain Medicine”PBLD: “Chronic Low Back Pain”Thoracic Workshop: Thoracic Epidural Anesthesia and AnalgesiaNew York, NY

National:

1991 St. Vincent Hospital, Erie, PA Anesthesia Grand Rounds; "Perioperative Cardiac Morbidity, pre-, intra- and postoperative management"

1991 Robert Packer Hospital-Guthrie Clinic Anesthesia Grand Rounds, Sayre, PA "Clinical Applications of Beta-Blockers in the Intra- and Postoperative Periods"

1991 Robert Packer-Guthrie Clinic, Surgical Intensive Care Grand Rounds, Sayre, PA "Improving Outcome in Critically Ill Surgical Patients"

1991 Robert Packer-Guthrie Clinic, Anesthesia Grand Rounds, Sayre, PA "Perioperative Fluid Therapy, Colloids vs Crystalloids"

1991 St. Vincent Medical Center, Pharmacy Grand Rounds, Erie, PA "Pharmacological Basis for Colloid and Crystalloid Fluid Therapy"

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1992 Hamot Medical Center, Anesthesia Dept. Grand Rounds, Erie, PA "Perioperative Cardiac Morbidity. Pre- Intra- and

Postoperative Management"1992 Robert Packer-Guthrie Clinic,

Surgical Grand Rounds. Sayre, PA "Postoperative Myocardial Ischemia. Diagnosis, Therapy and Outcome Results"

1992 Robert Packer-Guthrie Clinic "Preoperative Evaluation of Patients Undergoing Non-Coronary Vascular Surgery". Sayre, PA

1992 Department of Anesthesiology Grand Rounds, UMDNJ "Indications for Beta-Blockade in the Perioperative Period". Newark, NJ

1992 Department of Anesthesiology Grand Rounds, Roger Williams Hospital "Indication for Beta-Blockade in the Perioperative Period". Providence, RI

1992 Departments of Surgery, Anesthesiology and Cardiology Grand Rounds, Hamot Medical Center "Postoperative Myocardial Ischemia, Diagnosis,

Treatment and Influence onOutcome". Erie, PA1992 Walter Reed Medical Center, Critical Care Grand Rounds

"Postoperative Myocardial Ischemia: Diagnosis, Treatment and Influence on Outcome” Washington DC

1992 ASRA Workshop: Physiologic Consequences of Epidural Anesthesia. "Metabolic Consequences of

Epidural Blockade". Burlington, VT1992 ASRA Workshop: Physiologic Consequences of

Epidural Anesthesia. Burlington, VT "Regional Anesthesia for Head and Neck Procedures and the Airway". Burlington, VT

1992 ASRA Workshop: Physiologic Consequences of Epidural Anesthesia. "Does Regional Anesthesia Improve Clinical Outcome?” Burlington, VT

1992 St. Vincent's Hospital, Anesthesia Grand Rounds. "Perioperative Management of Patients with Coronary

Artery Disease". Erie, PA1993 Hackensack Medical Center,

Department of Anesthesiology Grand Rounds

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"Colloids vs Crystalloids". 1993 ASTRA Regional Anesthesia Workshop

"Ambulatory Anesthesia and Regional Techniques". Arlington, VA

1993 American Society of Regional Anesthesia 18th Annual Meeting "Workshop on Epidural and Interpleural Techniques”. Seattle, Wa

1993 ASTRA Regional Anesthesia Workshop "Ambulatory Anesthesia and Regional Techniques”. New Orleans, LA

1993 Yale University, Department of Surgery Grand Rounds. "Perioperative Fluid Management of the Critically Ill”. New Haven, Conn

1993 ASTRA Regional Anesthesia Workshop "Postoperative Pain Management of the Surgical Patient”. Walnut Creek, CA

1993 ASTRA Regional Anesthesia Workshop "Regional Anesthesia for Ambulatory Surgical Patients”. Pittsburgh, PA

1993 Third Symposium of Home Care "Ambulatory Pain Management of Patients with Chronic Pain and Opioid Dependency" Denver, Colorado

1993 UMDNJ, Department of Surgery Grand Rounds "Perioperative Fluid Utilization in the Trauma Patient”. Newark, NJ

1993 Morristown Hospital, Critical Care Grand Rounds. "Optimizing preload in critically ill patients”. Morristown, NJ

1993 Regional Anesthesia Workshop "Does Regional Anesthesia and Analgesia Improve Clinical Outcome?" "Ambulatory Anesthesia and Regional Techniques".

Scottsdale, AZ 1993 Engelwood General Hospital,

Anesthesia Grand Rounds "Perioperative Management of Patients with Coronary Artery Disease". Engelwood, NJ

1994 East Orange VA Hospital, Internal Medicine Grand Rounds "Pharmacological Basis of Fluid Administration".

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East Orange, NJ1994 Darmouth-Hitchcock Medical Center,

Anesthesiology Department Conference "Perioperative Fluid Management in High Risk Surgical Patients". Hanover, NH

1994 American Society of Regional Anesthesia, Annual Meeting 1. Celiac and Superior Hypogastric Plexus Blocks for Cancer Pain

Management. Workshop2. Pre-emptive Analgesia. Does it Exist? Does it Matter?3. Epidural Analgesia for Patients Undergoing Non-Cardiac

Surgery: Cardiac Outcome. Chicago, Il

1994 McKean County Medical Society Pharmacological Management of Cancer Pain. Bradford, PA

1994 ASTRA Regional Anesthesia Workshop "Surgical Outcome: General Anesthesia versus Epidural Anesthesia and Analgesia". Newark, NJ

1994 New Jersey Society of Anesthesiologist Meeting "Surgical Outcome: General Anesthesia versus Epidural Anesthesia and Analgesia". Clark, NJ

1995 American Society of Regional Anesthesia, Annual Meeting Thoracic Epidural Anesthesia. Workshops

1995 Medical College of Ohio, Anesthesiology Grand Rounds "Continuous Infusions of Local Anesthetics, Opioids or

Combinations for Postoperative Analgesia" Toledo, Ohio

1995 Toledo Medical Oncology Society "Pharmacological Management of Cancer Pain" Toledo, Ohio

1995 American Society of Anesthesiology Meeting: Panel on Care of the Critically Ill Patient:

"Perioperative Myocardial Ischemia" Atlanta, Georgia 1996

Review and Update in Pain Medicine "Pharmacological Management of Cancer-Related Pain"

"Neurolytic Techniques for Cancer Pain Management” 1996 ASRA Regional Refresher Course.

"Epidural Anesthesia and Analgesia for Thoracic and Abdominal Procedures"

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"Does Regional Anesthesia and Analgesia Improve Outcome?" Epidural Anesthesia and Analgesia for Patients With CAD

Undergoing Non-Cardiac Surgery" Workshop: "Cervical and Thoracic Epidural Techniques" Atlanta, Georgia

1996 South County Hospital Staff Grand Rounds "Preoperative Anesthesia Assessment in Patients with CAD" Wakefield, Rhode Island

1996 Pain Management in the 90's Holmes Regional Medical Center "Cancer and Acute Pain Management" "Managing Cancer Pain: Pharmacological and Invasive Approaches" Melbourne, Florida

1996 American Society of Regional Anesthesia Annual Meeting "Open Forum: A Comparison of Isoflurane Anesthesia Versus Spinal Lidocaine Anesthesia on Cellular Immunity Function Using

Immunophenotypic Multiparameter Analysis and Natural Killer

Cell Cytotoxicity""Workshop: Celiac, Hypogastric, Ganglion Impar Blocks""Cancer Pain Treatment: Invasive Strategies"San Diego, California

1996 American Society of Cardiovascular Anesthesiologist's Annual Meeting"Thoracic Epidural Anesthesia in Pain Management"Workshop: "Thoracic Epidural Anesthesia"Salt Lake City, Utah

1996 Metrohealth Medical CenterDepartment of Anesthesia Grand Rounds"Choosing a Drug or Combination of Drugs for Your Acute Pain

Service: What Does the New Literature Support?"Cleveland, Ohio

1996 Meridia HospitalDepartment of Anesthesia Grand Rounds"Choosing a Drug or Combination of Drugs for Your Acute Pain Service: What Does the New Literature Support?"Cleveland, Ohio

1996 Fairview General HospitalDepartment of Anesthesia Grand Rounds"Choosing a Drug or Combination of Drugs for Your Acute Pain Service: What Does the New Literature Support?"Cleveland, Ohio

1996 Case Western Reserve University Hospital

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Department of Anesthesia Grand Rounds"Choosing a Drug or Combination of Drugs for Your Acute Pain Service: What Does the New Literature Support?"Cleveland, Ohio

1996 The Cleveland Clinic FoundationDepartment of Anesthesia Grand Rounds"Choosing a Drug or Combination of Drugs for Your Acute Pain

Service: What Does the New Literature Support?"Cleveland, Ohio

1996 American Society of Regional Anesthesia. Symposium on “Future Directions of Acute Pain Management”“Benefits of Regional Anesthesia/Analgesia: Immuno Modulation”“Special Situations in Regional Anesthesia/Analgesia: OpiateTolerant Patient”“Special Situations in Regional Anesthesia/Analgesia:

Vertificationof the Block”“Future Directions for Outcome Research in Acute Pain

ManagementHigh Risk Patients”Orlando, Florida

1996 American Society of Regional Anesthesia, Regional Meeting“Does Regional Anesthesia Influence Outcome”Workshop:” Thoracic Epidural Anesthesia”New York, New York

1996 Hamot Medical Center“What is New in Acute Pain Management”Erie, PA

1996 Department of Medicine, Division of Medical OncologyUniversity of Kansas“Pharmacological Management of Cancer Pain”Kansas City, MO

1996 Department of Anesthesiology Grand Rounds, St. Luke’s Hospital“Thoracic Epidural Techniques for the Perioperative Period”Houston, Texas

1996 Department of Neuro-Oncology Grand Rounds, MD Anderson Medical Center“Opioid Tolerance: From the Laboratory to the Clinic”Houston, Texas

1997 Multidisciplinary Review and Update in Pain MedicineAllegheny University of Health Sciences“Pharmacological and Invasive Management of Cancer Pain”Somerset, Pennsylvania

1997 American Society of Regional Anesthesia (ASRA) Annual

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MeetingWorkshop: “Neurolytic Techniques for the Celiac Plexus andThe Superior Hypogastric Plexus”Atlanta, GA

1997 American Society of Cardiovascular Anesthesia (SCVA)“Physiologic Effects of Thoraic Epidural Anesthesia and

Analgesia”Workshop:”Thoracic Epidural Anesthesia Techniques”Baltimore, MD

1997 Hands-on Workshop for Interventional Pain Management“Thoracic Epidural: Clinical Applications in Chronic PainManagement”“Interpleural Analgesia: Clinical Applications in Chronic PainManagement”Workshop: “Thoracic Epidural Techniques”

“Interpleural Techniques” “Celiac Plexus Techniques”

“Superior Hypogastric Plexus Techniques” “Ganglion Impar Block Techniques”

Houston, TX1997 Virginia Mason “Sleepless in Seattle Conference”

“Regional Anesthesia for Cancer Patients”Workshop: “Brachial Plexus Blocks: Axillary Approach”

1997 American Society of Regional Anesthesia“Regional Anesthesia: Does “Preempting Pain Improve Outcome”“Thoracic Epidural Anesthesia Workshop”Chicago, IL

1997 American College of Surgeons Annual MeetingPanel Discussion on Acute Pain ManagementChicago, IL

1997 American Society of Anesthesiologists (ASA) Annual MeetingModerator: “Novel Approaches on the Management of Acute

Pain”“Acute Pain Management in Opioid Tolerant Patients: From theBench to the Clinic”San Diego, CA

1998 Multidisciplinary Review and Update in Pain MedicineAlleghency University of Health Sciences“Pharmacological Management of Cancer Pain”“Invasive Management of Cancer Pain”Keystone, Colorado

1998 Department of Anesthesiology Grand RoundsErie Hospital“Perioperative Myocardial Ischemia”

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Erie, PA1998 American Society of Regional Anesthesia Regional Workshop

“How to Make your Acute Pain Service Effective”“Thoracic Epidural Anesthesia Techniques” Louisville, KY

1998 MD Anderson Cancer Center2nd Hands-on Interventional Pain Workshop“Chemical Sympathectomy for Cancer Pain”“Thoracic and Cervical Epidural Catheter Placement”Houston, TX

1998 Department of Internal Medicine Grand RoundsEast Tennessee State UniversityJames H. Quillen College of Medicine“Perioperative Management of the High Risk Cardiac Patient”Johnson City, TN

1998 American Society of Anesthesiology Annual MeetingWorkshop: “Celiac Plexus and Superior Hypogastric Blocks”“Morphine is the Ideal Agent for Postoperative Epidural

Analgesia: PRO”Moderator Panel on: “Regional Techniques for Cancer Pain

Management”“New Invasive Strategies for the Treatment of Cancer Pain”“How to Rescue a Patchy Postoperative Epidural: What Works and

What Doesn’t”Seattle, WA

1998 Southern New England Anesthesia Conference“Invasive Strategies for Out-Patient Pain Management”Newport, RI

1998 American Society of Anesthesiology Regional Meeting“Making your Acute Pain Service Work”“Thoracic Epidural Workshop”Chicago, IL

1999 III Hands-On Interventional WorkshopMD Anderson Cancer Center“Neurolysis of the Sympathetic Axis for Cancer Pain

Management”Workshop: “Celiac Plexus Blocks”

“Superior Hypogastric Plexus Block” “Ganglion Impar Block”

Houston, Texas1999 American Society of Regional Anesthesia Annual Meeting

“Combined Regional/General Anesthetics for Aortic Surgery: Should We Be Using Local Anesthetics”: PRO

Workshops: “Celiac and Hypogastric Plexus Blocks”

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Philadelphia, PA1999 Virgina Mason Medical Center Biannual Meeting

“Invasive Techniques in the Future for Pain Management”“Neurolytic Blocks for Cancer Pain Management”Seattle, WA

1999 Chicago Society of Anesthesiologist“Neurolytic Blocks of the Sympathetic Axis for Cancer Pain Management”“Epidural Anesthesia and Analgesia for High Risk Surgical Patients”“Invasive Techniques in the Future for Pain Management”Chicago, IL

1999 American Society of Anesthesiology Meeting“Improving Outcome in High Risk Surgical Patients with Epidural Techniques”Dallas, TX

2000 American Society of Regional Anesthesia and Pain Management MeetingWorkshop: “Hands on Cadaveric workshop on Celiac Plexus Block”Workshop: “Celiac Plexus and Superior Hypogastric Plexus Blocks”Panel Moderator: Pain Medicine“Spinal Infusion Systems for Cancer Pain”“Organization and Management of the Cancer Pain Service”Orlando, Fl

2000 Illinois Neurologic Society “Update on Cancer Pain Management: Current and Future Trends”Bloomington, Ill

2000 Philadelphia Anesthesia Society“Improving Outcome with Epidural Anesthesia and Analgesia Techniques”Philadelphia, PA

2000 American Society of Anesthesiology Meeting“Thoracic Epidural Anesthesia”San Francisco, CA

2001 MD Anderson Hands-On Workshop“Neurolytic Blocks of the Sympathetic Axis for Cancer Pain”Houston, Texas

2001 American Society of Anesthesiology Meeting“Thoracic Epidural Anesthesia for Thoracic Surgery”“What is New in Epidural Techniques and Cardiac and ICU Outcome”New Orleans, LA

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2002 MD Anderson Hands-On Workshop“Neurolytic Blocks of the Sympathetic Axis for Cancer Pain”Houston, Texas

2002 American Society of Regional Anesthesia Meeting“Multimodal Perioperative Therapy for Patients Undergoing Abdominal Surgery” Panel ModeratorChicago, IL

2002 American Society of Anesthesiology Annual MeetingThoracic Epidural Anesthesia and Analgesia WorkshopOrlando, FL

2002 American Society of Regional Anesthesia and Pain“Invasive Therapies for Advanced Disease States: Intrathecal Therapy in Cancer Patients”“PBLD: Cancer Pain Management”“Lunch with the Experts: Pancreatic Cancer Pain Management”Scottsdale, AZ

2003 American Pain Society“Emerging Knowledge of Side Effects and Complications of Analgesic Therapy” Panel ModeratorChicago, IL

2003 American Society of Regional Anesthesia Spring Meeting“Local Anesthetic Toxicity”“Multimodal Therapy for Surgical Patients”San Diego, CA

2003 American College of Physicians’ Annual Meeting“Advances in Analgesic Therapy: CINODs”San Diego, CA

2003 American Society of Family Physicians’Annual Meeting“Advances in Analgesic Therapy”New Orleans, LA

2003 American Society of Anesthesiology Annual MeetingWorkshop: “Thoracic Epidural Anesthesia”San Francisco, CA

2003 American Society of Regional Anesthesia and Pain Annual Meeting

“Pharmacological Treatment of Cancer Related Pain”Master Class: “Neurolytic Blocks”San Diego, CA

2003 New York State Society of Anesthesiology Annual MeetingPBLD: “Diagnosis and Treatment of Low Back Pain”Thoracic Anesthesia Workshop: “Thoracic Epidural Anesthesia and Analgesia

2004 American Academy of Pain Medicine Annual MeetingRefresher Sessions: “Pain Perception, Translation, and

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Modulation”Refresher Sessions: “Does Treatment of Acute Pain Prevent Chronic Pain”

2004 American Society of Regional Anesthesia and Pain Annual MeetingModerator Session: “Pain and Obstetrics for the ‘Occasional’ AnesthesiologistWorkshop: “Thoracic Epidural Anesthesia”“Acute Pain in the Opioid Tolerant Patient”Orlando, FL

2004 American Society of Anesthesiology Annual MeetingWorkshop: “Thoracic Epidural Anesthesia”Las Vegas, NV

2005 American Society of Anesthesiology Annual MeetingWorkshop: “Thoracic Epidural Anesthesia”Workshop: “Neurolytic Sympathetic Blocks”Atlanta, GA

2005 American Society of Regional Anesthesia and Pain Annual Fall Meeting“Cancer Pain”Workshop: “Intrathecal Pump Implantation”PBLD: “Pain Management in the End of Life”

2006 American Society of Regional Anesthesia and Pain Annual Spring Workshop: The Patient with Neuro-deficit After a Peripheral Block

2006 American Society of Anesthesiology Annual MeetingRefresher Course Lectures: “Treatment of Cancer Pain”Workshop: “Visceral and Sympathetic Blocks”Panel: “Differences Between Opioid-Induced Tolerance and Hyperalgesia: Optimizing Treatment With Opioids and Adjuvant Therapy”Workshop: “Thoracic Anesthesia”Chicago, ILL

2006 American Society of Regional Anesthesia and Pain Annual Fall Meeting“Neuronal Plasticity and Pain: Basic and Clinical Science”Chair: Panel in “Cancer Pain Beyond WHO“Intrathecal Therapy for Cancer Related Pain: The Nuts and Bolts”PBLD: Cancer Pain What Would You Do? Controversial Cases DiscussionSan Francisco, CA

2006 New York State Society of Anesthesiology Annual MeetingPBLD: “Diagnosis and Treatment of Low Back Pain”Thoracic Anesthesia Workshop: “Thoracic Epidural Anesthesia

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and Analgesia2007 AAPM Annual Meeting

Chair: Panel in Cancer Pain“Implementing Intratheal Therapy: The Nuts and Bolts”New Orleans, LA

2007 Cleveland Clinic Foundation Annual Meeting“Intrathecal Polyanalgesia: Pros and Cons”“Sphenopalatine Ganglion Neurolysis”“Conventional versus Pulsed Radiofrequency: PRO”Orlando, FL

2007 The 44th Annual New York Anesthesiology Review“Neurobiology of Pain”“Update on Acute Pain Management”“What is New in Chronic Pain Management”Orlando, Fl

2007 American Society of Regional Anesthesia and Pain Annual Spring Workshop: Thoracic Epidural AnesthesiaPBLD: The Patient with Opioid ToleranceVancouver, Canada

2007 American Society of Anesthesiologists Annual MeetingPoster Facilitator: Chronic and Cancer Pain - Clinical and BasicWorkshop on Thoracic AnesthesiaTreatment of Cancer Pain: Refresher Course ASANeuromodulation for Visceral Pain PanelSan Francisco, CA

2007 American Society of Regional Anesthesia and Pain Annual Fall Meeting

PBLD: Pancreatic Cancer Pain ManagementWorshop 4: Visceral/ Sympathetic BlocksPBLD Luncheon 22: Cancer Pain ManagementParallel Session 5: Celiac/Visceral NeurolysisModerator: Cancer Pain Parallel Session Implementing Intrathecal Therapy in Cancer PainBoca Raton, FL

2008 AAPM MeetingChair Panel: Comprehensive Management of Neuropathic Pain in the Elderly“Invasive Techniques for the Treatment of Neuropathic Pain in the Elderly”Orlando, Fl

2008 American Society of Regional Anesthesia and Pain Annual Spring Meeting

Worshop: Thoracic Epidural Anesthesia and Analgesia

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2009 APS MeetingChair Panel: Treatment Strategies for Patients Not Responding to Incrased Doses of Opioids: An Analgesic Roadmap for CliniciansTampa, FL

International:

1992 International Courses for Medical Update Santa Ines Medical Center "The Importance of Acute Pain Management in the High

Risk Surgical Patients" Cuenca, Ecuador

1992 Department of Anesthesiology and Surgery Grand Rounds, Universidad del Ecuador, Quito.

"The Importance of Acute Pain Management in the High Risk Surgical Patients", Quito, Ecuador

1992 Ibero-American Congress of Anesthesiology Symposium on Visceral Pain, Barcelona, Spain Moderator

1992 Ibero-American Congress of Anesthesiology Chronic Pain Abstract Presentation, Barcelona, Spain. Chairman, Roundtable Discussion

1993 Clinica Las Condes' I Symposium on Regional Anesthesia: - "Indications, Advantages and Contra-indications to Regional Anesthesia" - "Workshop on Head and Neck Blocks" - "Does Postoperative Epidural Analgesia

Improve Clinical Outcome?" - "Complications of Regional Anesthesia" - "Neurolytic Superior Hypogastric Plexus Block”. Santiago, Chile

1993 Eleventh Annual Can-Am Clinical Anaesthesia Conference "Problems Associated with the Choice ofPostoperative Pain Control Technique"Niagara on the Lake, Ontario. Canada

1993 Nuevo Leon Society of Anesthesiology Meeting "The Use of Beta-Blockers in the Perioperative Period".

Monterrey, NL Mexico1993 Jalisco Society of Anesthesiolog Meeting

"The Use of Beta-Blockers in the Perioperative Period” Guadalajara, Jalisco. Mexico

1993 District One (Brooklyn-Queens Chapter) New York State Society of Anesthesiologists and

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SUNY at Brooklyn Panel Workshop on Pain Management "The Acute Postoperative Pain Service". Elbow Beach, Bermuda

1993 Ninth Annual Anesthesiology Course Mexican Society of Anesthesiology "Clinical Utilization of Beta-Blockers" "Postoperative Myocardial Ischemia: Diagnosis, Clinical Implications and Management" Mexico City, Mexico

1993 Mexican Society of Anesthesia Annual Meeting. "What is New in Perioperative Fluid Management" "Perioperative Management of High Risk Cardiac Patients Undergoing Non-Cardiac Surgery". Puerto Vallarta, Mexico

1993 Argentinian Society of Pain. Annual Meeting "Epidural Anesthesia and Analgesia for High Risk Patients: Is there More Beyond Pain Control" "Peripheral Opioid Receptors" "Neurolytic Superior Hypogastric Plexus Block for Pelvic Pain Associated with Cancer" "Epidural Opioid Therapy for Cancer Patients with Opioid Tolerance". Buenos Aires, Argentina

1993 Mexican Society for the Study and Treatment of Pain Annual Meeting "Alternatives to the Use of Morphine for Epidural Analgesia in

Patients with Opioid Tolerance" "Postoperative Pain Management" "Interpleural Analgesia for Cancer Pain" "Oral Pharmacological Management of Patients with Cancer Pain".

Mazatlan, Mexico1994 National Institute of Health of Mexico:

"The Tenth Medical Update Symposium" "Clinical Utilization of Short-Acting Beta-Blockers" "Clinical Utilization of Colloids and Crystalloids for Fluid Replacement" Mexico City, Mexico

1994 Mexico City General Hospital "The Eleventh International Meeting" "Colloid-Osmotic Pressure and Fluid Replacement" "Anesthetic Techniques for Patients with Coronary Artery Disease" "Regional or General Anesthesia for the High Risk Surgical Patient” "Peripheral Opioid Receptors"

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"Preemptive Analgesia: Physiologic Bases and Clinical Implications" Veracruz, Mexico

1994 II Symposium in Regional Anesthesia "Workshop on Superior Hypogastric Plexus Block" “Workshop on Fiberoptic Tracheal Intubation" "Pharmacological Management of Patients with Cancer Pain” "Sympathetic Neurolytic Blocks for Cancer Pain" "Complications and Side Effects of Epidural Analgesia" "Epidural Analgesia for High Risk Patients: Outcome Results" Santiago, Chile

1994 IV International Symposium in Critical Care and Emergency Medicine "Short-Acting Beta-Blocking Adrenergic Agents in the Critical

Care and Emergency Setting" Mexico City, Mexico

1994 VI International Congress in Pain Colombian Society of Anesthesiology "Epidural Anesthesia and Analgesia in High Risk Patients:

Outcome Results" "Advantages and Disadvantages of Regional Anesthesia" "Neurolytic Blocks for Cancer Pain" Bogota, Colombia

1994 XIX Annual Caribbean Symposium in Anesthesiology andRelated Fields

"Epidural Anesthesia and Analgesia in High Risk Surgical Patients" "Neurolytic Blocks for Cancer Pain Management"

San Juan, Puerto Rico1995 XVIII Symposium in Anesthesiology. Mexican Institute

of Social Services "Epidural Anesthesia and Analgesia in High Risk Patients: Outcome Results"

“Pros and Cons of Isovolemic Hemodilution" Chairman of Roundtable Discussion

"Thoracic Epidural Anesthesia and Analgesia in Cardiac Patients Undergoing Non-Cardiac Surgery"

"Regional Anesthesia for Ambulatory Surgery" Mexico City, Mexico

1995 I International Symposium on Acute Pain Management. Salvador Zubiran National Institute.

"Epidural Techniques for Postoperative Pain Control" "Epidural Anesthesia and Analgesia in Cardiac Patients

Undergoing Non-Cardiac Surgery"

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"Epidural Anesthesia and Analgesia in High Risk Patients: Outcome Results"

"Epidural Analgesia Complications" Mexico City, Mexico

1995 I International Partership Program. Du Pont Pharmaceuticals. "The Role of Pentaspan in Perioperative Fluid Management" Lisbon, Portugal

1995 II Symposium in Pain. The American British Cowdray Hospital. "The Care of a Patient Who is Dying" Mexico City, Mexico

1995 IV Regional Symposium on Pain Management Antioquian Society of Anesthesiology "Epidural Anesthesia and Analgesia in Cardiac Patients

Undergoing Non-Cardiac Surgery" "Epidural Anesthesia and Analgesia in High Risk Patients:

Outcome Results" "Neurolytic Blocks for Cancer Pain" "Pharmacological Management of Cancer Pain" Medellin, Colombia

1995 II International Course on Pain Management. Argentinian Society of Anesthesiology.

"Epidural Opioids and Combinations of Local Anesthetics and Opioids for Postoperative Analgesia"

"Complications and Side Effects Associated with Epidural Analgesia" "Neurolytic Blocks for Cancer Pain Management I" "Neurolytic Blocks for Cancer Pain Management II"

Buenos Aires, Argentina1995 XXIX Mexican Society of Anesthesia Meeting

"Chairman Round Table Discussion on Cancer Pain Management" "Pros and Cons of Epidural Analgesia" "Premptive Analgesia" "Epidural Fentanil: Pros and Cons" "Perioperative Blood Transfusion: Pros and Cons" "Oxygen Delivery" "Critical Oxygen Delivery" Tijuana, Mexico

1995 VI International Meeting on Medical and Surgical Critical Care. Mexico City General Hospital

Fluid Replacement in the Emergency Room" Mexico City, Mexico

1995 XX Mexican Society of Oncology Meeting "The use of Controlled Release Morphine in the Treatment

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of Cancer Pain" Monterrey, Mexico

1995 II Pan American Symposium on Regional Anesthesia "Regional Anesthetic Techniques for General Surgery" "Workshop on Thoracic and Cervical Epidural Techniques" "Opioid Spinal Analgesic Agents" Epidural Analgesia for Cardiac Patients Undergoing

non-Cardiac Surgery" Member of Panel Discussion on: "The Rational Management

of Pain: The Anesthesiologists' Role" Member of Panel Discussion on: "Postoperarative Analges”

Vina del Mar, Chile1995 XV International Congress of the Mexican Society for the

Study and Treatment of Pain "Choice of Opioids for Postoperative Pain Management:

Benefits and Risks" "Pain Management in the Critically Ill" Puerto Vallarta, Mexico

1996 I International Symposium on Critical Care "Neuromuscular Blocking Agents in the Intensive Care Unit" Mexico City, Mexico

1996 XIX Congress in Anesthesiology Federation of Societies of Anesthesiology of Mexico "Neuromuscular Blocking Agents in the Intensive Care Unit" "What is new in Neuromuscular Reversal" "Indications, Advantages and Contraindications of Regional

Anesthesia" Mexico City, Mexico

1996 European Society of Regional Anesthesia“Invasive Strategies in Cancer Treatment”“Regional Anesthesia Improves Postoperative Outcome: Pro”“Epidural Opioid Therapy for the Opioid Tolerant Patient”Nice, France

1996 Latin American Society of Regional AnesthesiaIII Regional Meeting“Immunomodulation and Anesthesia”“Perioperative Management of the Patient with a Thoracic

Epidural”“Choosing a Drug for Postoperative Pain Management“Complications Associated with Postoperative Analgesia”Workshop: “Thoracic and Cervical Epidural Techniques”Santiago, Chile

1996 Mexican Society of AnesthesiologyXXX Annual Meeting

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“Coronary Blood Flow in Patients with Coronary Artery Disease and

Normovolemic Hemodilution”“Alternatives for Blood: Where are we?”“Hemodynamic Monitoring of the Patient with Severe

Preeclampsia”Workshop-Luch “Acute Postoperative Pain Management”Monterrey, Mexico

1996 Venezuelan Pain SocietyII Annual Meeting“Pharmacological Management of Cancer Pain”“What is New in Neurolytic Blocks of Sympathetic Axis for

CancerPain”Caracas, Venezuela

1997 Hospital Espanol Medical Staff Grand Rounds“Pentaspan: A New Colloid for Fluid Replacement”Mexico City, Mexico

1997 Leon College of AnesthesiologistXI Symposium in Anesthesiology“Pentaspan: A New Colloid for Fluid Replacement”“Normovolemic Hemodilution in Patients with CAD”“New Alternatives for Fluid Replacement”“Update on Acute Pain Management”Leon, Guanajuato, Mexico

1997 Review on Acute Pain ManagementSociety of Anesthesiologists of Mexico City“Thoracic Epidural Anesthesia and Analgesia for High RiskSurgical Patients: Cardiac and Pulmonary Physiologic Effects”“Thoracic Epidural Anesthesia and Analgesia for CardiacPatients Undergoing Non-Cardiac Surgery”Mexico City, Mexico

1997 European Society of Anesthesiologist (ESA) Annual Meeting“Epidural Anesthesia and Analgesia Improves Outcome inHigh Risk Surgical Patients Undergoing Abdominal Surgery”Luassane, Switzerland

1997 European Society of Medical Oncology: Focus on Pain and Cancer Pain Management

“Cancer Pain: Clinical Research and Future Treatments”“US and European Experience with Transdermal Opioids”“Treatment of Cancer Pain with Alternatives to the Oral Route:Transdermal Therapeutic Systems”“Clinical Pathways and Treatment Alternatives for Cancer PainManagement”

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Limassol, Cyprus1997 Colombian Society of Anesthesiology Meeting

“Physiologic Effects of Thoracic Epidural Anesthesia and Analgesia

on Pulmonary and Cardiac Function”“Choosing an Opioid for Epidural Analgesia”“Thoracic Epidural Anesthesia and Analgesia for Patients with Cardiac Disease Undergoing Non-Cardiac Surgery”“Preoperative Evaluation of the High Risk Patient”

1997 Hospital for Cardiovascular Disease of Bucaramanga“Postopeative Myocardial Ischemia: Diagnosis, Prophylaxis andTreatment”

1997 Argentinian Society of Anesthesiology Meeting“Epidural Anesthesia and Analgesia for the High Risk Patient”“Regional Anesthesia for Ambulatory Surgery Patients”“Perioperative Management of Thoracic Epidural Techniques forPatients Undergoing Surgery Upon the Thorax and Abdomen”Cordoba, Argentina

1997 Society of Anesthesiologist of Antioquia“What is in the Future of Invasive Techniques for Cancer PainManagement”“Neurolytic Blocks for Cancer Pain Management: Interpreting theLiterature for Better Outcomes”“Neuropathic Pain: A Physiological View and Its Applications toClinical Practice”Medellin, Colombia

1997 Mexico City Pain Society“Infusion Systems for Pain Management”Mexico City, Mexico

1997 Brazilian Society of Anesthesiologist Annual Meeting“Esmolol: Clinical Uses”Belo Horizonte, Brazil

1997 Latin American Society of Regional Anesthesia (LASRA)Chair: Panel on “Does Regional Anesthesia and Analgesia

ImproveOutcome?”“Thoracic Epidural Anesthesia and Analgesia: Nuts and Bolts”“Choosing an Opioid for Epidural Analgesia: Decisions Based onPhysico-Chemical Characteristics”Cancun, Mexico

1998 Key Note Speaker at the Sunnybrook Health Science Centre“Sixth Annual Weber Lecture”Toronto, Canada

1998 Spanish Society of Pain

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Symposium in Cancer Pain“Invasive Therapeutic Alternatives for Cancer Pain Management”Barcelona, Spain

1998 National Institute of Cancer of MexicoSymposium on Anesthetic Perspectives for the 21st Century“Future Invasive Techniques for Cancer Pain Management”“Perioperative Myocardial Ischemia in the 21st Century”Mexico City, Mexico

1998 Colombian Society of Anesthesiology and the Colombian Society for the Study of Pain Annual Meeting

“Visceral Pain: The Forgotten Area in Chronic Pain Management”“What is New in the Treatment of Neuropathic Pain”“Future Invasive Strategies for the Treatment of Cancer Pain”

1998 XIX Mexico City Society of Anesthesiology Meeting“Perioperative Myocardial Ischemia”“Cisatracurium: Clinical Utilization”Mexico City, Mexico

1998 XXVII Argentinian Society of Anesthesiology Meeting andV South American Society of Anesthesiology Meeting“Thoracic Epidural Anesthesia: The Nuts and Bolts”“Neurolytic Blocks of the SympatheticAxis”“Drug Utilization in Anesthesiology”Iguazu Falls, Argentina

1998 IV Chilean Society of Regional Anesthesia Meeting“Future Invasive Techniques for Cancer Pain Management”“Neuropathic Pain: What is new in the Physiopathology and Treatment”“Visceral Pain: The Forgotten Area in Chronic Pain Management”“Neurolytic Blocks of the Sympathetic Axis”Workshop: “Fiberoptic Tracheal Intubation”Santiago, Chile

1998 University of Toronto Fifth Annual Regional Anesthesia and Analgesia Meeting“Neurolytic Blocks for Cancer Pain”Workshop: “Neurolytic Blocks for Cancer Pain Management”Toronto, Canada

1998 Guatemalan Society of Anesthesiology Meeting“Perioperative Diagnostic and Treatment of Myocardial Ischemia”“The Use of PCA for Pain Control”“Future Invasive Techniques for Cancer Pain Management”Guatemala City, Guatemala

1998 Spanish Society of Pain II Annual Meeting “Oncologic Pain: Diagnosis and Treatmen, an updatet”“Pelvic Pain: Diagnosis and Treatment, an update”

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Palma de Mallorca, Spain1998 XLIII Meeting of the Spanish Society of Anesthesiology

“Thoracic Epidural Anesthesia and Analgesia in Thoracic Surgery”

Moderator: Panel on Thoracic SurgeryGranada, Spain

1998 XXXII Mexican Federation of Anesthesiology Meeting“Perioperative Use of ECG for Diagnosis of Ischemia”“Remifentanil in Ambulatory Surgery”“Sepsis and the Anesthesiologist”Queretaro, Mexico

1998 Latin American Society of Anesthesiology Meeting“Invasive Techniques in Future for Chronic Pain Management”“Choosing an Opioid for Epidural Anesthesia: A Rational

Approach”“Cardiopulmonary Effects of Thoracic Epidural Blockade”Workshop: “Thoracic and Cervical Epidural Techniques”Punta del Este, Uruguay

1999 PuertoRican Society of Anesthesiology Meeting“Visceral Pain: The Forgotten Area in Chronic Pain Management”“Pharmacological Therapy for Cancer Pain”San Juan, Puerto Rico

1999 Argentinian Society of Pain Meeting“Improving Outcomes with Thoracic Epidural Anesthesia and

Analgesia: What is New in the Area”“Diagnosis and Treatment of Side Effects and Complications

Associated with Postoperative Epidural Analgesia”“Diagnosis and Treatment of Side Effects and Complications

Associated with Thoracic Epidural Anesthesia”Workshop: “Thoracic Epidural Techniques for Pain Management”Mendoza, Argentina

1999 Brazilian Society of Pain Biannual Meeting“What is New in Neuropathic Pain”“Thoracic Epidural Anesthesia and Analgesia: Nuts and Bolts”“Future Invasive Techniques for Cancer Pain Management”Sao Paulo, Brazil

1999 Argentinian Society of Anesthesiology Meeting“Pain Management in the Critical Care Units”“New Development in Pain Management”“Epidural Techniques: Improving Outcome in High Risk Patients”“Ropivacaine for Colon Surgery”Buenos Aires, Argentina

1999 Colombian Society of Anesthesiology Meeting“What is New in Spinal Anesthesia?”

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“Complications of Regional Anesthesia”“Thoracic Epidural Anesthesia and Analgesia: The Nuts and

Bolts”Medellin, Colombia

1999 Brazilian Society of Anesthesiology Meeting“The Indications for Beta-Adrenergic Receptor Blockade in the Perioperative Period”Porto Alegre, Brazil

2000 Curitiba Society of Anesthesiology Meeting“The Indications for Beta-Adrenergic Receptor Blockade in the Perioperative Period”Curitiba, Brazil

2000 Bahia Society of Anesthesiology Meeting“The Indications for Beta-Adrenergic Receptor Blockade in the Perioperative Period”Salvador, Brazil

2000 International Society of Regional Anesthesia (ISRA“How to choose an opioid for epidural administration in pain management”Moderator: “Setting up an Acute Pain Service”“What is the Future of the Multidisciplinary Pain Clinic”Quebec City, Canada

2000 World Congress in AnesthesiologyWorkshop: “Thoracic Epidural Anesthesia and Analgesia”Montreal, Canada

2000 Latin American Society of Regional Anesthesia (LASRA)“Thoracic Epidural Anesthesia: With or Without Tracheal Intubation”“Managing a Thoracic Epidural Analgesia Service”Workshop: “Thoracic Epidural Anesthesia”Sao Paulo, Brazil

2000 Key Note Speaker: University of Toronto Seventh Annual“Regional Anesthesia and Pain Medicine 2000” Meeting“Invasive Techniques for Cancer Pain Management”Workshop: “Neurolysis of the Sympathetic Axis”Toronto, Canada

2001 Spanish Society of Pain Management Annual Meeting“Multi-modal Therapy to Speed-Up Recovery of Patients Undergoing Abdominal Surgery”“Neurolytic Bloks of the Sympathetic Axis for Cancer Pain”Barcelona, Spain

2001 CAN-AM Anesthesia Conference“The New Local Anesthetics: Are They Worthy of Your Clinical

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Practice”Niagara on the Lake, Canada

2001 Argentinian Society of Anesthesiology Meeting“What is New in Thoracic Epidural Anesthesia”“New Developments in Epidural Analgesia”Round Table Discussion: “Combined Epidural-General Anesthesia”Bariloche, Argentina

2001 Spanish Society of Regional Anesthesia“Epidural Techniques for Cardiac Surgery, Is it Possible?”Moderator Panel: “What is new in epidural anesthesia and analgesia”“Optimizing Intrathecal Solutions for Cancer Pain Management”“Data Management in the Pain Service”Cadiz, Spain

2001 Brazilian Pain Society Annual Meeting“Cancer Pain Management: State of the Art”“Sympathetic Blocks for Cancer Pain Management”Rio de Janeiro, Brazil

2001 Brazilian Society of Anesthesiology Meeting“Thoracic Epidural Anesthesia: Physiological Effects on the Heart, the Lungs and the Splanchnic Circulation”“Thoracic Epidural Anesthesia: Treating Side Effects”“Perioperative Treatment of Hypertension and Myocardial

Ischemia”2002 Spanish Society of Pain

“Improving Patient’s Recovery With Epidural Techniques”2002 Pain Society of Panama

“Myofascial Pain Syndrome”“Acute Pain Therapy: State of the Art”“Pharmacological Therapy for Cancer Pain”“Invasive Therapies for Cancer Pain”Colon, Panama

2002 Mexican Society of Anesthesiology Meeting“What is New in Spinal Anesthesia”“COX-2 Inhibitors for Acute Pain ManagementVeracruz, Mexico

2003 Argentinian Society of Anesthesiology“Pharmacological Treatment of Cancer Pain”“Invasive Techniques for Cancer Pain”Workshop: “Thoracic Epidural”Mendoza, Argentina

2004 Colombian Cancer Institute70th Anniversary Meeting

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“Strategies to Optimize Intrathecal Therapy in Patients with Cancer Related Pain”“Spinal Cord Stimulation for the Treatment of Cancer Related Pain”Bogota, Colombia

2004 Argentinian Medical Society Meeting“Diagnosis and Treatment of Low Back Pain”“COX-2 Inhibitors: Pitfalls in their use”Buenos Aires, Argentina

2005 European Congress of Orthopedic Anesthesia“The Management of Breakthrough Pain”CHAIR: Postoperative Pain Management SessionCHAIR: Computers in Anesthesia Session“Postoperative Pain: An Update”Barcelona, Spain

2005 World Congress of PainMember of Panel “Safety Aspects of Postoperative Pain Management”Sydney, Australia

2006 Annual Meeting of the Spanish Society of Pain“Opioids in Cancer Related Pain”Gran Canarias, Spain

2005 AOSRA Bi-Annual Meeting“Neuromodulation for Cancer Related Pain”Chiba, Japan

2006 World Congress of Regional Anesthesia and Pain“Neurolysis of the Sympathetic Axis for Cancer Pain”“Opioids for Chronic Non-Cancer Pain”“The Role of Acute Pain Services”Rio de Janeiro, Brazil

2006 Pain Society of Argentina Annual Meeting“What is New In Epidural Opioid Therapy”“Spinal Cord Stimulation for Cancer Pain”“Optimizing Results with Intrathecal Therapy”“Neurolytic Blocks of the Sympathetic Axis: Are They Still Indicated?”Buenos Aires, Argentina

2006 Spanish Rheumatology Association, Annual Meeting“Neurobiology of Neuropathic Pain”Valencia, Spain

2006 12th International Pain Clinic Congress“Invasive Techniques for Cancer Related Pain”“Improving Quality of Life in Cancer Patients”“Current Status of Pain Medicine in the US”

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“Spinal Cord Stimulation for Cancer Related Pain”Chair: “Unusual Pain Syndromes” Panel.Turin, Italy

2006 Regional ESRA Meeting“What is New in Spinal Anesthesia”“Thoracic Epidural Anesthesia: The Nuts and Bolts”Buenos Aires, Argentina

2006 35 Argentinean Congress in Anesthesiology“Fast Track Anesthesia for Colonic Surgery”“Epidural/General Anesthesia: Why”“Pain in Cancer”“Perioperative Management of the Cancer Patient”Mar de Plata, Argentina

2007 II International Congress of Pain MedicineMadrid Pain Society“Epidural Steroids: In Whom, When and How”“Iontophoretic Analgesics”“Intraspinal Adjuvant Agents”

2007 XXXIII Mexican College of Anesthesiology Meeting“Neuropathic Pain”“Epidural Steroid Injections: The Nuts and Bolts”Mexico City, Mexico

2007 3rd International Forum on Pain Medicine“Spinal and Supraspinal Gating of Pain Signals”“Outcome Results on Epidural Steroid Injections”Chair: Meet the Expert Session June 29th from 14:30 to 17:30Montreal, Canada

2007 European Society of Regional Anesthesia - Spain“Sophistry in Regional Anesthesia and Pain Management”“Extended Release Epidural Morphine: Nuts and Bolts”“Topical Analgesia: Analgesia Without Side Effects”

2007 Ibero-American Meeting of AnesthesiologySofismo en Anestesia Regional y Dolor AgudoCOMO SE ASOCIAN LA SENSIBILIDAD DEL SISTEMA NERVIOSO Y LA INFLAMACION?COMO PUEDE EL ANESTESIOLOGO INHIBIR LA SENSIBILIDAD CENTRAL?Cancun, Mexico

2008 World Congress of Anesthesia“Pharmacological Therapy for Cancer Pain”“Invasive Techniques for Cancer Pain Management”Cape Town, SA

2008 Colombian Society for the Study of Pain “Pros and Cons of Spinal Cord Stimulation”“Epidural Steroid Injections: From A to Z”

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“Controversies in Neuropathic Pain”Bogota, Colombia

2008 IberoAmerican Symposium on Pain“Neurobiology of Pain”“Epidural Steroids: From A to Z”“Cancer Pain Management”“What is new in Sodium Channel Biology and Clinical

Applications”Isla Margarita, Venezuela

2008 Guatemalan Society of Anesthesiology Annual Meeting“Sophistry in Regional Anesthesia and Pain”“Epidural Steroids: The Nuts and Bolts”“Opioids for Non-Cancer Pain”“Comprehensive Cancer Pain Management”Guatemala City, Guatemala

Research Activities:

Physiology and Pharmacology of Epidural Opioids Physiology of Epidural Anesthesia Perioperative Surgical Outcome Thoracic and Cardiac Anesthesia Perioperative Cardiac Morbidity Beta Adrenergic Blockade in Anesthesiology Peripheral Opioid Receptors Acute Pain Control Chronic Cancer Pain

Thesis Advisor for Postgraduate Trainees:

Medical Doctors

Dora Karabela 1992Gustavo Navarro 1997 Heikel Ashraff 1998

Research Electives for Medical Students:

Brian Parker 7-91 - 10-91 Elizabeth McClintick 6-92 - 9-92

Phillip Ehrlich 6-96 - 9-96

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Training of Pain Fellows:

2000 – 2001: Etienne DeMedicis, MD and Say Gundavarpu, MD2001 – 2002: Mark Mathews, MD and Kondeker Rahman, MD2002 – 2003: Alfredo Quevedo Vela, MD2003 – 2004: Salah Eldohiri, MD and Fayez Kotob, MD2004 – 2005: Julio Paez, MD and Juan Diego Harris, MD2005 – 2006: Chad Wilde, MD and Atiq Rehman, MD2006 – 2007: Joseph Ghahhari, DO and Nora Rajaee, MD2007 – 2008: Bradley Urie, MD and Rebecca Chang, MD2008 – 2009: Bernard Hsu, MD and Todd Schultz, MD

Membership in Professional Societies:

1987-1990 American Medical Association 1989-1991 American College of International Physicians 1989- American Society of Regional Anesthesia

1989-1993 American Society of Cardio-Thoracic Anesthesia1990- American Society of Anesthesiologists1990- New York State Society of Anesthesiologists1991 - American Pain Society1993 – 1999 Society of Critical Care Medicine2000 - 2006 Eastern Pain Association

Appointments at National Societies:

2002 - 2004 Treasurer. Eastern Pain Association2003 - Member, Pain Management Committee, NYSSA2005 - Member, Board of Directors of ASRA

2005 - Ad Hoc Scientific Content Subcommittee on Pain Medicine of the American Society of Anesthesiologist (ASA) 2006 ASA Task Force to Update Practice Guidelines for Chronic Pain for the year 2006 2007 ASA Task Force to Update Practice Guidelines for Chronic Pain for the year 2007 2007 ASA Committee on Regional Anesthesia

Committee Service:

National:

1992 - 1994 Advisory Committee Du Pont Pharmaceuticals1994 American Society of Regional Anesthesia.

Nineteenth Annual Meeting, Chicago, IL

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1994 Scientific Program Committee, ASRA Annual Meeting1997 American Society of Regional Anesthesia1997 Advisory Committee, Pain Section Abbott Laboratories1997 Consultant to the Anesthesia and Respiratory Therapy Devices

Panelof the Medical Devices Advisory Committee, Center for Devicesand Radiological Health, FDA.

1998 Advisory Committee, Regional Anesthesia, Abbott Laboratories2003 - American Society of Regional Anesthesia

Education Committee2004 - NCCN Pain Management Guidelines Committee2006 - NYSSA Pain Management Committee

Scientific Committees

1994 - 1995 American Society of Anesthesiologist (ASA) Subcommittee on Local Anesthesia and Pain

1994 American Society of Regional Anesthesia (ASRA) Research Committee

1995 - 1996 American Society of Anesthesiologists (ASA) Local Anesthetics and Pain subcommittee

1995 - 1997 1996 PGA Sub-Committee on Scientific Programs1996 - 1997 American Society of Anesthesiologists (ASA)

Drug Deposition and Anesthetic Action Subcommittee 1998 American Society of Regional Anesthesia (ASRA)

Scientific Program Committee 2000 Eastern Pain Association (EPA)

Scientific Program Committee 2001 Eastern Pain Association (EPA)

Chairman, Scientific Committee 2002 Eastern Pain Association (EPA)

Scientific Program Committee 2003 American Society of Regional Anesthesia (ASRA)

Scientific Program Committee 2003 – 2004 American Society of Regional Anesthesia and Pain (ASRAPM)

Chairman, Scientific Program Committee, 2004 Fall Meeting 2005 American Society of Regional Anesthesia and Pain (ASRAPM)

Member, Scientific Program Committee, 2005 Fall Meeting2005 – 2006 American Society of Anesthesiologist (ASA)

Member, Ad Hoc Scientific Content Subcommittee on Pain Medicine

State of New York:

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1992 - 1993 Alternate Delegate, District #7 NYSSA1995 - 1998 Alternate Delegate, District #7 NYSSA

Roswell Park Cancer Institute:

1991 - 1996 Scientific Review Committee of the IRB1990 - 1991 Pharmacy-Pharmacology Committee1991 - 1995 Pharmacy Drug Use Evaluation Subcommittee1990 - 1991 Drug Delivery systems subcommittee1991 - 1993 Critical Care Committee1992 - 1995 Pharmacy-Pharmacology Committee (Chairman)1992 - 1995 Executive Committee1993 - 1998 Critical Care Committee (Chairman)1993 - 1998 Critical Care QA Subcommittee (Chairman)1993 - 1998 Nutritional Advisory Committee1994 - 1998 Critical Care Utilization Subcommittee (Chairman)1998 - 1999 Critical Care Committee (member)2000 - 2001 Institutional Review Board (IRB)

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GRANT SUPPORT:

Principal Investigator

1992 - 1993 Grant Name: Bard Infusion Systems Young Investigator Award in Pain Management. (Single Center)Co - Investigator : Mark J. Lema, PhD, MDWork Title: Postoperative Epidural Bupivacaine-Morphine Therapy: Experience with 4227 Surgical Cancer PatientsAmount: $10,000. Time contributed to the project: 80%

1992 - 1993 Grant Name: Du Pont Pharma Educational Grant. (Single Center) Co - Investigator : Mark J. Lema, MD, PhDWork Title: Postoperative Epidural Bupivacaine-Morphine Therapy: Experience with 4227 Surgical Cancer Patients

Amount: $15,000. Time contributed to the project: 80%

1994 Grant Name : Cobe Laboratories Educational Grant. (Single Center) Co - Investigator : Basab K. Mookerjee, MDWork Title: Epidural Analgesia versus Intravenous PCA: Differences in the Postoperative Course of Cancer PatientsAmount: $5000. Time contributed to the project: 80%

1994 Grant Name : Amicon, Inc Educational Grant. (Single Center)Co - Investigator : Basab K. Mookerjee, MDWork Title: Epidural Analgesia versus Intravenous PCA: Differences in the Postoperative Course of Cancer PatientsAmount: $5000.Time contributed to the project: 80%

1994 Grant Name : Quinton Co. Educational Grant. (Single Center)Co - Investigator s: none

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Work Title: Epidural Analgesia versus Intravenous PCA: Differences in the Postoperative Course of Cancer PatientsAmount: $3000. Time contributed to the project: 80%

1995 - 1999 Grant Name: Carl Koller Memorial Research Grant. (Single Center) Co - Investigators : Miguel A. Reina, MD, Andres Lopez, MD. Jose A. de Andres, MD.Work Title: An in Vitro Study of Dural Lesions Produced by 25-gauge Quincke and Whitacre Needles Evaluated by Scanning Electron MicroscopyAmount: $10,000. Time contributed to the project 40%

1995 - 1996 Grant Name: Abbott Infusion Systems Research Educational Grant. (Single Center)Co-Investigator: Mark J. Lema, MD, PhDWork Title: Randomised, Double-Blind Comparison of Epidural

and Intravenous Fentanyl Therapy for Postoperative PainAmount: $20,000. Time contributed to the project: 70%

1996 -1997 Grant Name: Knoll Pharmaceuticals Educational Grant. (Single Center) Co-Investigators: Robert P. Sands, MD, Anthony Yarussi, MD, Mark J. Lema, MD, PhDWork Title: Peripheral Morphine Analgesia for Postoperative Pain Following Axillary Node Dissection for Breast Cancer: A Controlled, Randomized, Double-Blind StudyAmount: $30,000. Time contributed to the project: 80%

1997 - 1998 Grant Name: Baxter Technologies Educational Grant. (multi-center)

Co-Investigators: Ricardo Plancarte, MD, Mai El Helely, MDWork Title: Neurolytic Superior Hypogastric Plexus Block for Chronic Pelvic Pain Associated with CancerAmount: $5000. Time contributed to the project: 60%

1998 - 2000 Grant Name: ASTRA Pharmaceuticals Educational Grant (multi-center)Co-investigators: Myriam Hincapie, MD, Omar Gomezese, MD,

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Jaime Martina, MD, Jorge Castro, MDWork Title: Perioperative Myocardial Ischemia in Patients Undergoing Abdominal Aortic Surgery: The Cardioprotective Effects of Perioperative Epidural Anesthesia and AnalgesiaAmount: $30,000. Time contributed to the project: 40%

2001 - Grant Name: Astra-Zeneca Research Grant. (Single Center) (DS-01-06)Co-investigators: Anthony Yarussi, MD, Lorraine Howard, RN, Satish Velagapudi, MDProtocol Title: A Multi-Modal Rehabilitation Program for Patients Undergoing Radical Prostatectomies”

Amount: $40,000. Time spent on project: on-going

2001 - Grant Name: Roxane Laboratories Research Grant. (Single Center) (DS-01-06)Co-investigators: Anthony Yarussi, MD, Lorraine Howard, RN, Satish Velagapudi, MDProtocol Title: A Multi-Modal Rehabilitation Program for Patients Undergoing Radical Prostatectomies”

Amount: $2,000. Time spent on project: on-going

2002 - Grant Name: Janssen Laboratories Research Grant (Single Center)Co-investigators: noneProtocol Title: Cancer Pain Education in the CommunityAmount: $7000Time spent on the project: on-going

Co-Investigator

1993 - 1994 Grant Sponsor: Glaxo Postoperative Emesis Study Group (Multi-center)Co - Investigators : 91 across the countryWork Title: Ondansetron for postoperative emesis prophylaxisAmount: $4500Time contributed to the project: 1.09%

1998 – 2001 Grant Sponsor: Fund of Investigation of the Ministry of Health of Spain, project # 98/0628

Principal Investigator: Miguel A. Reina, MD

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Co-Investigators: Oscar A. de Leon-Casasola, MD, Andres Lopez, MD, Jose A. de Andres, MD, Miguel Mora, MD, Agustin Fernandez, MD

Project Title: Ultrastructure Definition of the of the Spinal Membranes by Transmission and Scanning Electron MicroscopyAmount: $85,345Time contributed to the project: 20%

2000 - 2001 Grant Sponsor: Scirex Corporation. (multi-center) (DS-99-22)Co-investigators at RPCI: Mark J. Lema, MD, PhD, Pauline Cole, NP, Lorraine Howard, RNProtocol Title: A Phase III Study of Oral Numorphan in Cancer Patients.

Budget: $21,890. Time contributed to project: 20%

2000 - 2001 Grant Sponsor: Scirex Corporation. (multi-center) (DS-99-24)Co-investigators at RPCI: Mark J. Lema, MD, PhD, Pauline Cole, NP, Lorraine Howard, RNProtocol Title: A Cross-over Study of Oral Numorphan versus Oral MS-Contin and Oxy-Contin in Cancer Patients.

Budget: $47,844. Time contributed to project: 10%

2000 - 2001 Grant Sponsor: Quintiles/Searle (multi-center) (DS-00-09)Co-investigators at RPCI: Mark J. Lema, MD, PhD, Pauline Cole, NP, Lorraine Howard, RNProtocol Title: A Phase III Study of Valdecoxib in Cancer Patients Receiving Oral Opioid Therapy.

Budget: $72,060Time contributed to project: 20%

2004 - Grant Sponsor: Elan (multi-center)Co-investigators at RPCI: Mirjana Lovrincevic, MDProtocol Title: A Phase III Study of Ziconotide in Cancer PatientsBudget: $25,000Time contributed to project: 1%

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BOOKS PUBLISHED

1. Cancer Pain – Pharmacological, Interventional, and Palliative Care Approaches. De Leon-Casasola OA, ed.Philadelphia, Saunders Elsevier, 2006.

PUBLICATIONS:

Original Articles: Refereed Journals

1. de Leon-Casasola OA, Lema MJ, Emrich L, Syed N: Continuous 2-Chloroprocaine Infusion Versus Intermittent Bolus Injections of Bupivacaine or2-Chloroprocaine for Epidural Anesthesia in Cesarean Delivery. Regional Anesthesia 1991; 16:154-160

2. de Leon-Casasola OA, Lema MJ: Anesthesia for Patient With Sturge-Weberand Klippel-Trenaunay Syndrome . J of Clin Anesth 1991; 3:409-413

3. de Leon-Casasola OA, Lema MJ: Atrioventricular Dissociation Resulting From Combined Thoracic Epidural and General Anesthesia. Acta Anaesthesiol Scand 1992 36:165-169

4. de Leon-Casasola OA, Lema MJ: Epidural Sufentanil for Acute Pain Control in a Patient with Extreme Opioid Dependency. Anesthesiology 1992; 76:853-856

5. Lema MJ, Myers DP, de Leon-Casasola OA. Interpleural Phenol Therapy for the Treatment of Chronic Esophageal Cancer Pain. Regional Anesthesia 1992;17:166-170

6. de Leon-Casasola OA, Weiss A, Lema MJ: Anaphylactic Shock Due to Propofol.Anesthesiology 1992 77:384-386

7. de Leon-Casasola OA, Myers DP, Lema MJ, et al.A Comparison of Postoperative Epidural Analgesia between Patients with Chronic

Cancer Taking High Doses of Oral Opioids versus Opioid-naive Patients.

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Anesth and Analg 1993;76:302-307

8. de Leon-Casasola OA, Kent E, Lema MJ: Neurolytic Superior Hypogastric Plexus Block for Chronic Pelvic Pain Associated with Cancer. Pain 1993;54:145-151

9. Myers DP, Lema MJ, de Leon-Casasola OA, Bacon DR: Interpleural Analgesia for the Treatment of Cancer Pain in Terminal Patients. J of Pain and Symptom Management 1993;8:505-510

10. de Leon-Casasola OA, Lema MJ: Postoperative Pain Management in Patients with Opioid Dependency. Pain Digest 1993; 3:110-111

11. de Leon-Casasola OA, Lema MJ: Epidural Bupivacaine/Sufentanil Therapy for Postoperative Pain Control in Patients Tolerant to Opioid and Unresponsive to Epidural

Bupivacaine/Morphine. Anesthesiology 1993; 80:303-309

12. de Leon-Casasola OA: Postoperative Pain Management for Surgical Cancer Patients: Give Me The Top Shelf Stuff Doctor.

Seminars in Anesthesiology 1993;12:103-108

13. de Leon-Casasola OA: Postoperative Pain Management in Cancer Patients. Is There More Beyond Pain Control? Problems in Anesthesia. 1993;7:474-485

14. Myers DP, de Leon-Casasola OA, Bacon DP, et al: Bilateral Pneumothoraces from a Malfunctioning Resuscitation Valve. J of Clin Anesth 1993;5:433-435

15. de Leon-Casasola OA, Parker B, Lema MJ, et al: Epidural Analgesia versus Intravenous PCA: Differences in the Postoperative Course of Cancer Patients. Regional Anesthesia 1994;19:307-315

16. de Leon-Casasola OA, Parker B, Lema MJ, et al: Postoperative Epidural Bupivacaine-Morphine Therapy: Experience with 4227

Surgical Cancer Patients. Anesthesiology 1994;81:368-375 17. de Leon-Casasola OA, Piver MS: Epidural Anesthesia and Analgesia for Postoperative Pain Control in Patients

with Gynecologic Cancer. The Female Patient 1995;20:35-45

18. de Leon-Casasola OA, Lema MJ, Karabella D, et al:

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Postoperative Myocardial Ischemia: Epidural versus Intravenous PCA Analgesia: Pilot Study. Regional Anesthesia 1995; 20:105-112

19. Nader-Djalal N, de Leon-Casasola OA, Peer GL, et al: The Influence of Preoperative Concentrations of B-Endorphin and Met-Enkephalin

on the Duration of Analgesia after Transurethral Resection of Prostate Anesthesia and Analgesia 1995;81:591-595

20. de Leon-Casasola OA, Karabella D, Lema MJ:Bowel Function Recovery after Radical Hysterectomies: Thoracic EpiduralBupivacaine/Morphine versus Intravenous PCA Morphine: A Pilot Study. J of Clinical Anesthesia 1996;8:87-92

21. de Leon-Casasola OA, Lema MJ: Postoperative Epidural Opioid Analgesia: What are the Choices? Anesthesia and Analgesia 1996;83:867-875

22. de Leon-Casasola OAImmunomodulation and Epidural Anesthesia and AnalgesiaRegional Anesthesia 1996;21(6S):24-25

23. de Leon-Casasola OAPostoperative Pain Management in Opioid-Tolerant PatientsRegional Anesthesia 1996;21(6S):114-116

24. de Leon-Casasola OAVerification of Sensory Block During Regional AnesthesiaRegional Anesthesia 1996;21(6S):126-128

25 de Leon-Casasola OA New concepts in postoperative pain management: is there more beyond pain control? Journal of the Florida Medical Association 1996;83:695-700

26. de Leon-Casasola OASuperior Hypogastric Plexus Block and Ganglion Impar Neurolysis for Pain Associated

withCancer.Techniques in Regional Anesthesia and Pain Management 1997;1:27-31

27. Sands R, de Leon-Casasola OA, Harrison P, et al: Randomised, Double-Blind Comparison of Epidural and Intravenous Fentanyl

Therapy for Postoperative Pain.Acute Pain 1997;1:7-14

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28. Plancarte R, de Leon-Casasola OA, El-Helaly M, et al.: Neurolytic Superior Hypogastric Plexus Block for Chronic Pelvic Pain Associated with

Cancer.Regional Anesthesia 1997;22:562-569

29. Sands R, Yarussi T, de Leon-Casasola OA:Complications and Side Effects Associated with Epidural Bupivacaine/Morphine

AnalgesiaAcute Pain 1998;1:43-50

30. de Leon-Casasola OAThoracic Epidural Anesthesia and Analgesia for Thoracic Surgery in High Risk Surgical Patients: A Physiological Appraisal of Pulmonary and Cardiac Function and Its Influence

on Patient Outcome.Techniques in Regional Anesthesia and Pain Management 1998;2:35-40

31. de Leon-Casasola, OAPostoperative Pain Management in Patient Who Are Opioid TolerantProblems in Anesthesia 1998;10:103-106

32. de Leon-Casasola OAThe Use of Low Molecular Weight Heparin and Other Deep Venous Thrombosis

Prophylaxis With Regional Anesthesia.Revista Argentina de Anestesiologia (Argentinian Society of Anesthesiology Journal) 1998;56:317-322

33. Yarussi A, Sands R, Edge S, Lema MJ, de Leon-Casasola OAPeripheral Morphine Analgesia for Postoperative Pain Following Axillary Node

Dissection for Breast Cancer: A Controlled, Randomized, Double-Blind Study. Regional Anesthesia 1999;24:142-145

34. Stevens R, de Leon-Casasola OA.Combined Thoracic Epidural and General Anesthesia: When is it Indicated?Acute Pain Journal 1999;2:89-96

35. de Leon-Casasola, OANeurolytic Blocks of the Sympathetic Axis for the Treatment of Visceral Pain in Cancer. Current Review of Pain 1999;3:173-177

36. de Leon-Casasola, OACritical Evaluation of Chemical Neurolysis of the Sympathetic Axis for Cancer Pain.Cancer Control 2000;7:142-148

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37. de Leon-Casasola OA, Stevens RomThoracic Epidural Anesthesia and Analgesia for Cancer Surgery: The Importance of the Anesthetic TechniqueTechniques in Regional Anesthesia and Pain Management 2000;4:69-76

38. de Leon-Casasola, OAThoracic Epidural Anesthesia and Analgesia for Colon Cancer Surgery: A Multimodal Approach to Favor Early Hospital Discharge. Argentinian Society of Anesthesiology Journal 2000;58:25-29

39. de Leon-Casasola, OAHow To Make Thoracic Epidural Anesthesia and Analgesia a Safe Technique: Issues in Patient Management. Anesthesiology News (Special Report), January 2000

40. de Leon-Casasola OA, Yarussi A Pathophysiology of Opioid Tolerance and Clinical Approach to the Opioid-Tolerant Patient. Current Review in Pain 2000;4:203-205

41. Reina MA, de Leon-Casasola OA, Lopez A, De Andres J, Martin S, Mora M.An in Vitro Study of Dural Lesions Produced by 25-gauge Quincke and Whitacre Needles Evaluated by Scanning Electron Microscopy. Reg Anesth Pain Med 2000;25:393-402

42. Magimbi AS, de Leon-Casasola OASpinal Cord Stimulation. Techniques in Regional Anesthesia and Pain Management 2000;4:132-136

43. De Medicis E, de Leon-Casasola OAReversible Paraplegia Associated with Lumbar Epidural Analgesia and Thoracic Vertebral MetastasisAnesthesia Analgesia 2001;92:1316-1318

44. de Leon-Casasola OA, de Medicis E.My Patient With Rectal Cancer Does Not Have Pain Control Despite High Doses of Opioids and Optimal Doses of Gabapentin and Desipramine. Now What? Advanced Strategies for Cancer Pain ManagementTechniques in Regional Anesthesia and Pain Management 2000; 4:167-173

46. de Leon-Casasola OA, Zevon MSuccess with JCAHO Pain Management StandardsAnesthesiology News (Special Report), October 2000

47. De Medicis E, de Leon-Casasola OACritical Evaluation of the Ganglion Impar Block

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Techniques in Regional Anesthesia and Pain Management 2001;5:120-122

48. Reina MA, de Leon-Casasola OAThe Origin of the Spinal Subdural Space: Ultrastructure FindingsAnesthesia and Analgesia 2002;94:991-995

49. de Leon-Casasola OAHow should I treat refractory metastatic cancer pain? International Monitor on Regional Anesthesia and Pain Therapy 2002;13:4:3-6

50. de Leon-Casasola OA, Rahman KMAdvanced Strategies for Cancer Pain Management With Intraspinal Therapy.Seminars in Pain Medicine. In press

51. de Leon-Casasola OACellular Mechanisms of Opioid Tolerance and The Clinical Approach To The Opioid Tolerant Patient in the Postoperative PeriodBest Practice and Research in Clinical Anaesthesiology 2002;16:521-525

52. Reina MA, Lopez A, Maches F, de Leon-Casasola OA, de Andres JA.Electron Microscopy and the Expansion of Regional Anesthesia KnowledgeTechniques in Regional Anesthesia and Pain Management 2002;6:165-171

53. Lopez A, Reina MA, Maches F, de Leon-Casasola OA, de Andres JA, Garcia JElectron Microscopy in Quality Control of Equipment Used in Regional AnesthesiaTechniques in Regional Anesthesia and Pain Management 2002;6:172-179

54. Chaparro LE, Santos X, de Leon-Casasola OA. The Effects of Perioperative Epidural Techniques on the Incidence of Postoperative Complications: Analysis of conflicting Results. Revista Argentina de Anestesiologia 2002;60:299-308

55. de Leon-Casasola OA, Rahman K.Invasive Strategies for Cancer Pain ManagementSeminars in Pain Medicine 2003;1:1-6

56. de Leon-Casasola OA.Using a Multi-Modal Rehabilitation Program for Patients Undergoing Open Sigmoidectomy.Surgical Technology International 2003;49-52

57. de Leon-Casasola OA, Quevedo-Vela AIntraspinal Drug Delivery for Chronic Pain. Cancer Patients: Special ConsiderationsSeminars in Pain Medicine 2004;2:27-35

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58. Reina MA, deLeon-Casasola OA, Villanueva MC, et al.Ultrastructural Findings in Human Spinal Pia Mater in Relation to Subarachnoid AnesthesiaAnesthesia and Analgesia 2004;98:1479-1485

59. Vallejo R, de Leon-Casasola OA, Ramsim BenyaminOpioid Therapy and Immunosuppresion: A reviewAmerican Journal of Therapeutics 2004;11:1-12

60. Vanderah TW, de Leon-Casasola OA, Viscusi ERAnesthesiology News (Special Report) July, 2004

61. de Leon-Casasola OAInterventional Procedures for Cancer Pain Management: When are they indicated?Cancer Investigation 2004;22:630-642

62. De Andres J, Valıa JC, Cerda-Olmedo G, Quiroz C, Villanueva V, Martinez-Sanjuan V, de Leon-Casasola OA

Magnetic Resonance Imaging in Patients with Spinal Neurostimulation Systems Anesthesiology 2007; 106:779–86

63. de Leon-Casasola OA.Multimodal approaches to the management of neuropathic pain: the role of topical analgesia. Journal of Pain & Symptom Management 2007;33:356-64

64. de Leon-Casasola OASpecial Article – Bonica LecturerReg Anesth Pain Med 2008;32:240-241

65. de Leon-Casasola OACurrent Developments in Opioid Therapy for the Management of Cancer PainClin J Pain 2008;24:S3-7

66. de Leon-Casasola OAImplementing Therapy with Opioids in Patients with Cancer. Oncology Nursing Forum 2008;35(6): S1-6

Guest Editor:

1998 Guest Editor of Techniques in Regional Anesthesia and Pain Management. Issue on “Regional Anesthesia for Thoracic

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Surgery”, January, Vol. 2, Number 1.

1999 Guest Editor of Current Review of Pain issue on “Cancer Pain”,Volume 4, Number 3.

2000 Guest Editor of Techniques in Regional Anesthesia and Pain Management. Issue on “Problems Encountered During

Regional Anesthesia and Pain Management”October, Vol 4, Number 4.

2001 Guest Editor of Techniques in Regional Anesthesia and Pain Management. Issue on “Ropivacaine for Clinical Practie”April, Vol 5, Number 2.

2002 Guest Editor of Techniques in Regional Anesthesia and Pain Management. Issue on “Technology in Regional Anesthesia”October, Vol 6, Number 4.

Editorials:

1. de Leon-Casasola OA,Analgesia Subaracnoidea Postoperatoria con Opioides: Balanceando riesgos y beneficios(Postoperative Analgesia with Opioids: A Balance of Risks and Benefits) Revista Espanola de Dolor (Journal of the Spanish Society of Pain) 1997;4:91-93

2. de Leon-Casasola OA,When it comes to outcome, we need to define what constitutes an epidural anesthesia and analgesia technique.Anesthesia and Analgesia 2003;96:315-318

3. Gebhardt R, de Leon-Casasola OA.Should we use air for the loss of resistance technique when finding the epidural space?Revista Espanola de Anestesiologia 2005;

Commentaries:

1. de Leon-Casasola, OAComparison of three solutions of ropivacaine/fentanyl for postoperative patient controlled epidural analgesiaThe International Monitor of Regional Anesthesia and Pain Therapy 1999;11:4:17

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2. de Leon-Casasola, OAStatistical differences do not always equal clinical differences. The International Monitor of Regional Anesthesia and Pain Therapy 2000;12:2:30

3. de Leon-Casasola, OAIs it fair to compare two different drugs administered via different techniques?The International Monitor of Regional Anesthesia and Pain Therapy 2000;12:4:19

4. de Leon-Casasola, OAGood sample size plus good study design equals good dataThe International Monitor of Regional Anesthesia and Pain Therapy 2001;13:1:7-8

5. de Leon-Casasola, OAIn the search of new drugs for intraspinal analgesia……and the treatment of their side effects.The International Monitor of Regional Anesthesia and Pain Therapy 2001;13(2)27

6. de Leon-Casasola OARespiratory Monitoring in the perioperative period in patients with chronic obstructive pulmonary disease.The International Monitor of Regional Anesthesia and Pain Therapy 2001;13(4)19-20

7. de Leon-Casasola, OAMore on the efficacy and safety issue of local anaesthetics: is the epidural route a good study model to answer these questions.The International Monitor of Regional Anesthesia and Pain Therapy 2002;14(3) 19

8. de Leon-Casasola, OAGabapentin: Everything you need to know about this drugThe International Monitor of Regional Anesthesia and Pain Therapy 2002;14:4

9. de Leon-Casasola, OAA Recipe to Obtain Results Beyond Adequate Pain Control: Thoracic Epidural Perioperatively Plus a Local Anaesthetic, Early Ambulation and Forced Enteral Nutrition.The International Monitor of Regional Anesthesia and Pain Therapy 2003;15(1):7

10. de Leon-Casasola, OAEffects of Epidural Anesthesia on Intestinal Oxygenation: The last piece of the puzzle.The International Monitor of Regional Anesthesia and Pain Therapy 2003;15(2):28

11. de Leon-Casasola, OA

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Cost and Analgesic Effectiveness: good outcome parameters in analgesic trials, provided that equianalgesic doses are used.The International Monitor of Regional Anesthesia and Pain Therapy 2003;15(3):18

12. de Leon-Casasola, OA To Block or not to Block: That is the question

The International Monitor of Regional Anesthesia and Pain Therapy 2004;16(3):20-21

Original Articles: Non-refereed Journals

1. de Leon-Casasola OA, Lema MJ: Pain in the Cancer Patient: Acute Postoperative Pain Services for Cancer Patients. The Solution. Option Care Inc. May-June 1991

2. de Leon-Casasola OA, Lema MJ: Establishing an Acute Postoperative Pain Service. Roswell Park Journal 1992; 3:6-7

3. de Leon-Casasola OA, Lema MJ: Postoperative Pain Management in Patients with Opioid Dependency. Solution.

Option Care Inc. December 1992

Letters to Editors:

1. Curletta JD, de Leon-Casasola OA: Epidural anesthesia in patients with coronary artery disease. Anesthesiology 1990; 72:214

2. de Leon-Casasola OA, Bacon D: Alternative approaches for insertion of Swan-Ganz catheters.

J of Cardiovasc Anesth 1990; 4:780-781

3. de Leon-Casasola OA, Lema MJ: Epidural opioid requirements. Anesthesiology 1991; 74:1158-1159

4. de Leon-Casasola OA, Lema MJ: Epidural anesthesia in patients with Klippel-Trenaunay syndrome. Anesthesia Analgesia 1992; 74:470-471

5. de Leon-Casasola OA, Lema MJ: Intensive Analgesia Reduces Postoperative Myocardial Ischemia? Anesthesiology 1992; 77:404-405

6. de Leon-Casasola OA, Plancarte R, Patt R, et al. Superior Hypogastric Plexus Block Using a Single Needle and CT Guidance.

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Regional Anesthesia 1993; 18:63

7. de Leon-Casasola OA, Lema MJ: Postoperative Pulmonary Complications: II. Anesthesiology 1993;79:1149

8. de Leon-Casasola OA, Lema MJ: Reply to G. Orlandini's Letter to the Editor. Pain 1994; 56:122

9. de Leon-Casasola OA, Lema MJ: Reply to M. Visentin's Letter to the Editor. 1994; 57:132-133

10. de Leon-Casasola OA, Lema MJ: Regional versus General Anesthesia for Peripheral Vascular Surgery. Anesthesiology, 1996;85:224-225

11. de Leon-Casasola OA, Lema MJ: Postoperative Epidural Analgesia: What are the Choices?Reply to do Santos’ Letter to the Editor. Anesthesia and Analgesia 1997;85:463

12. de Leon-Casasola OA, Lema MJ: Thoracic Epidural Anesthesia and Analgesia and Postoperative Myocardial IschemiaAnesthesia and Analgesia 1998;87:745-746

12. de Medicis E. de Leon-Casasola OA. MRI Diagnosis of Intracranial Hypotension.Canadian Journal of Anaesthesia. 2001;48:830

13. Harris JD, de Leon-Casasola OA. Oral erythromycin and the risk of sudden death. N. Eng J Med 2005;352:301-304

14. Kotob F, de Leon-Casasola OA, Lema MJ.NSAIDs and cardiovascular risk.Cell Metab. 2005;2:339

15. Kotob F, Harris JD, de Leon-Casasola OA.Methadone in the Management of Intractable Non-malignant Pain.Can J Neurol Sci. 2006; 33:116

16. de Leon-Casasola OATansforaminal Epidural Steroid Injections.Regional Anesthesia and Pain Medicine 2008;33:190-191

Book Chapters:

1. de Leon-Casasola OA, Lema MJ.

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Spinal Opioid Analgesia: Influence on Clinical Outcome.In: Sinatra RS, Hord AH, Ginsberg B, Preble LM, eds. Acute Pain: Mechanisms and Management. St. Louis, Mosby Year Book, 1992:293-303

2. de Leon-Casasola OA.Critical Care in Gynecology Oncology. In: Piver S, ed. Handbook of Gynecology Oncology. Boston, Little, Brown and Co. 1996;323-344

3. de Leon-Casasola OA. Improved Surgical Outcome After Epidural Anesthesia and Analgesia. In: Brown D, ed.

Textbook of Regional Anesthesia and Analgesia. Philadelphia, W.B. Saunders Company, 1996;658-670

4. Ditonto E, de Leon-Casasola OA, Plancarte R. Neurolytic Blockade for the Management of Pain. In: Ashburn MA and Rice LJ, ed.

The Management of Pain. New York, Churchill Livingstone, Inc. 1998;489-518

5. de Leon-Casasola OA, Ditonto E. Visceral Pain. In: Abrams S, ed. Atlas of Anesthesia, Volume IV, Pain Management.

Philadelphia, Churchill Livingstone, Inc. 1998;7.1-7.11

6. de Leon-Casasola OASuperior Hypogastric Plexus Block Neurolysis for Cancer PainIn: Benzon H, Raja SN, Molloy R, Borsook D, Strichartz G, eds. Essentials of Pain Medicine and Regional Anesthesia. New York, Churchill Livingstone, 1999 pp 325-328

7. Xue B, Lema MJ, de Leon-Casasola OAGanglion Impar Block In: Benzon H, Raja SN, Molloy R, Borsook D, Strichartz G, eds. Essentials of Pain Medicine and Regional Anesthesia. New York, Churchill Livingstone, 1999 pp 329-331

8. de Leon-Casasola OA,Complicaciones y Efectos Secundarios de la Analgesia Epidural en el Tratamiento del Dolor Postoperatorio(Complications and Side Effects Associated with Postoperative Epidural Analgesia)In: Aliaga L, ed. Regional Anestesia Hoy (Regional Anesthesia Today). Barcelona, Permanye, 1999;467-473.

9. Joseph PN, de Leon-Casasola OAThe use of Neurolytic Blocks and Other Neuroablative Techniques in Cancer PainManagement. In: Abram S, Haddox D, eds. The Pain Clinic Manual, 2nd editionPhiladelphia, Lippincott Williams and Wilkins 1999;375-392

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10. de Leon-Casasola OA, Ditonto EDrugs Commonly Used for Nerve Blocking: Neurolytic Agents. In: Raj PP, eds.Practical Management of Pain, 3rd editionPhiladelphia, Mosby 2000;575-578

11. de Leon-Casasola, OASympathetic Nerve Blocks: Pelvic. In Raj PP, eds.Practical Management of Pain, 3rd editionPhiladelphia, Mosby 2000;683-688

12. De Medicis E, de Leon-Casasola OARecent Advances in Regional AnesthesiaRegional Anesthesia for Cardiothoracic Surgery. ed Chaney MA. Lippincott, Williams and Wilkins, 2002, pp 1-20

13. De Medicis E, de Leon-Casasola OANeurolytic BlocksClinical Pain Management – Practical Applications and Procedures. Ed Breivik H, Campbell W, and Eccleston C. Arnold, 2003, pp 247-254

14. Rauck R, de Leon-Casasola OASympathetic Nerve BlockPain Medicine – A Comprehensive Review. Ed. Raj P. Mosby 2003, pp 250-271

15. de Leon-Casasola OA, Lema MJ

Cancer Pain. In, Healy TEJ and Knight PR eds,Wylie and Churchill-Davidson’s A Practice of Anaesthesia, 7th EditionLondon, Arnold. 2003. pp 1255-1265

16. de Leon-Casasola OA, Molloy RE, Lema MJNeurolytic Visceral Sympathetic Blocks. Celiac Plexus Block, Superior Hypogastric Block, Ganglion Impar Block. In: Benzon H, Raja SN, Molloy R, Borsook D, Strichartz G, eds. Essentials of Pain Medicine and Regional Anesthesia. 2nd Edition New York, Elsevier, 2004 pp 542-549

17. De Medicis E, de Leon-Casasola OALocal Anesthetic Toxicity in the Ambulatory Setting. In: Steele SM, Nielsen KC, Klein SM, eds. Ambulatory Anesthesia – Perioperative Analgesia. 1st Edition New York, McGraw Hill Medical, 2005 pp 207-213

18. de Leon-Casasola OACancer Pain Management in the Opioid Tolerant Patient. In de Leon-Casasola OA, ed. Cancer Pain: Pharmacological, Interventional and Palliative Care Approaches. 1st Edition Philadelphia. Saunders/Elsevier, 2006 pp 231-234

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18. Deschner C, Allen M, de Leon-Casasola OAEpidural Blockade. In: Hadzic A, ed. Textbook of Regional Anesthesia and Acute Pain Management. 1st Edition New York, McGraw Hill Medical, 2007 pp 229-267

19. de Leon-Casasola OAComplications Associated with Superior Hypogastric and Ganglion Impar Blocks. In Neal JM, Rathmell JP, eds Complications in Regional Anesthesia & Pain Medicine. 1st Edition Philadelphia. Saunders/Elsevier, 2007 pp221-226

20. Harris JD, Leon-Casasola OA, Chejne GF. Manejo del Dolor cronico agudizado y postoperatorio en el paciente con cancer dependiente de opioides. In: Plancarte SR, Clinicas Oncologicas de Iberoamerica, Manejo del dolor y cuidados Paliativos en el paciente con Cancer. Mexico. Intersistemas, S.A: de C.V. 2006, 189:204 ISBN 9706559116

AUDIO-VISUAL PRESENTATIONS:

1992 Audio-Visual Program. Seventeenth Annual Meeting of the American Society of Regional Anesthesia March 1992. Tunneled Thoracic Epidural Catheter Placement.

1992 Basic Lecture/Video. ASRA Workshop, Physiologic Consequences of Epidural Anesthesia. "Regional Anesthesia for

Head and Neck Procedures and the Airway".

1998 Audio-Digest“The Opioid Tolerant Patient: No Longer a Problem in Postoperative Pain

Management”

ABSTRACT PRESENTATIONS:

1. de Leon-Casasola OA, Lema MJ, Emrich L, Syed N: Comparison of continuous 2-chloroprocaine infusion with procaine for epidural anesthesia in cesarean delivery and the influence on postoperative pain management. Presented at The Meeting of the Society of Obstetric Anesthesia

and Perinatology. Madison, WI 1990

2. de Leon-Casasola OA, Myers DP, Doniparthi S, Bacon DR, Peppriell J, Rempel J, Lema MJ. Postoperative epidural analgesia for chronic cancer patients taking oral narcotics.

Anesthesiology 1991; 75:A665

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3. de Leon-Casasola OA, Myers DP, Rempel J, Bacon DR, Peppriell J, Lema MJ. A prospective analysis of epidural catheter

migration in 1598 surgical cancer patients. Anesthesiology 1991; 75:A730

4. de Leon-Casasola OA, Myers DP, Doniparthi S, Bacon DR, Peppriell J, Rempel J, Lema MJ. A Comparison of Post-operative Epidural Analgesia Between Chronic Cancer Patients Taking High Doses of Oral

Narcotics and Narcotic Naive Patients. Award of Excellence at the Second Annual Upstate Academic Anesthesia Conference. Rochester, NY., 1991 and at the Postgraduate Assembly in Anesthesiology. New York, NY

5. Kent E, de Leon-Casasola OA, Lema MJ. Neurolytic Superior Hypogastric Plexus Block for Cancer Related Pelvic Pain. Regional Anesthesia 1992; 17:S19

6. de Leon-Casasola OA, Kirch D, Karas P, Syed N, Blumenson L, Lema MJ. A Comparison of Epidural Bupivacaine-Fentanyl and Bupivacaine Sufentanil infusions for Relieving Labor Pain. Regional Anesthesia 1992; 17:S39

7. de Leon-Casasola OA, Myers DP, Rempel J, et al. Analisis Prospectivo de Migracion de Cateteres Epidurales en 2220 Pacientes Quirurgicos con Cancer. Rev Esp Anest y Reanim 1992; 32:S41-42

8. de Leon-Casasola OA, Kent E, Lema MJ. Bloque Neurolitico del Plexo Hipogastrico Superior para Dolor Pelvico Cronico Asociado con Cancer Rev Esp Anest y Reanim 1992; 32:S57

9. de Leon-Casasola OA, Myers DP, Donaparthi S, et al. Estudio Comparativo de Analgesia Epidural Postoperatoria entre Pacientes con Cancer en Tratamiento Cronico deOpioides y

Pacientes sin Uso Preoperatorio de Opioides. Rev Esp Anest y Reanim 1992; 32S42

10. de Leon-Casasola OA, Lema MJ. Epidural Sufentanil Provides Superior Analgesia for Opioid Tolerant Patients Unresponsive to Epidural Morphine. Anesthesiology 1992; 77:A855

11. de Leon-Casasola OA, Parker B, Schwartz C, et al. Postoperative Epidural Analgesia Decreases Length of Hospitalization and ICU

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Stays in High Risk Surgical Cancer Patients. Anesthesiology 1992; 77:A899

12. de Leon-Casasola OA, Parker B, Myers DP, et al. Experience Using Epidural Bupivacaine-Morphine Infusions for Postoperative Analgesia in 2843 Cancer Surgical Patients. Anesthesiology 1992; 77:A856. First Place at the Third Annual Upstate Academic Anesthesia Conference, 1992.

Rochester, NY

13. de Leon-Casasola OA, Kirch D, Karas P, et al. The Influence of Birthweight and Oxytocin in the Quality of Epidural Analgesia During Labor. Anesth Analg 1993;76:S73

14. de Leon-Casasola OA, Karabela T, Lema MJ: The Effect of Epidural Bupivacaine-Morphine and Intravenous PCA Morphine on Bowel Function and Pain After Radical Hysterectomies. Anesth Analg 1993;76:S74

15. de Leon-Casasola OA, McClintick E, Harrison P, et al. The Addition of Intramuscular Ketorolac to Epidural Morphine-Bupivacaine

for Post-Thoracotomy Analgesia. Regional Anesthesia 1993; 18:2S-74

16. de Leon-Casasola OA, Karabela T, Harrison P, et al. A Decrease in Postoperative Myocardial Ischemia and Infarction by Epidural

Bupivacaine-Morphine in Upper Abdominal Surgery. Regional Anesthesia 1993; 18:2S-66

17. Bacon DR, de Leon-Casasola OA, Myers DP, et al. Minutes of the American Society of Regional Anesthesia: 1924-1939.

Anesthesiology 1993; 79:A1028

18. Bacon DR, de Leon-Casasola OA, Lema MJ. Society Seals: Symbols of Organized Anesthesia. Anesthesiology 1993; 79:A1029

19. Nader-Djalal N, Peer G, de Leon-Casasola OA, et al: Preoperative Levels of B-Endorphin and Met-Enkephalin and the Duration of Analgesia After TURP Under Spinal Anesthesia. Anesthesiology 1994; 81:A1056

20. Sands R, de Leon-Casasola OA, Harrison P, et al: Epidural Fentanyl Action, Like Intravenous Fentanyl, Occurs Primarily at the

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Supraspinal Level. Regional Anesthesia 1995; 20:2S-40

21. O'Leary K, de Leon-Casasola OA, Lema MJ: Thoracic Epidural Anesthesia for the Repair of Bronchopleural Fistulas. Regional Anesthesia 1995; 20:2S-100

22. Plancarte R, de Leon-Casasola OA, Lema MJ: Alternative Approaches for Superior Hypogastric Plexus Block. Regional Anesthesia 1995; 20:2S-90

23. Sands R, de Leon-Casasola OA, Harrison P, et al: A Randomized, Double-Blind Compariso of Epidural and Intravenous Fentanyl

Therapy for Postoperative Pain: Epidural Administration Induces Acute Tolerance. Anesthesiology 83:A:844, 1995

24. Plancarte R, de Leon-Casasola OA, Allende S, et al: Neurolytic Superior Hypogastric Plexus Block for Pelvic Pain Associated with Cancer:

A Multicenter Experience with 159 patients. Anesthesiology 83:A843, 1995

25. Reina MA, Lopez A, de Andrers JA, de Leon-Casasola OA: Anatomic Correlation of the Subarachnoid Space and Its Membranes with the CaudaEquina Syndrome Via Scanning Electron Microscopy. Anesthesiology 1997;87:A740

26. Reina MA, Lopez A, de Andres JA, de Leon-Casasola OA: Electron Microscope Evaluation of the Dural Lesions Produced by Two Types ofSpinal Needles. Anesthesiology 1997;87:A783

27. Bashaw H, Barrick C, de Leon-Casasola OA, Zevon MA.Gender and Response to Cancer Related versus Non-cancer PainAmerican Association of Behavioral Therapy. 2006 Meeting

28. Kotob F, de Leon-Casasola OA, Lema MJIntrathecal Infusion Rates of 1 mL/day Improve Narrow Analgesia With Infusion Rates of 0.5 mL/day. Anesthesiology 2006; 105: A347

29. Demmy T, de Leon-Casasola OAInterpleural Bupivacaine Delivered by Chest Tube Improves Pain Control and Decreases 24 h Opioid Use After VATS.Southern Thoracic Surgical Association 2008; Abstract ID 34610

NEWS INTERVIEWS:

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1992 "Migration of Epidural Catheters into Subdural or Subarachnoid Space Called a Rare Event". Anesthesiology News 1992; 18(1):31

1993 "Bupivacaine Morphine Mixture Proves Efficacious for Pain Relief and Recovery from Hysterectomy"

Anesthesiology News 1993; 19(6):20

1993 "Epidurals Found to Decrease Postoperative Ischemia andTachycardia in High-Risk Abdominal Surgeries”Anesthesiology News 1993; 19(9):17-18

1994 "New Anesthesia Procedure Proves Heart-Saving" Internal Medicine World Report 1994, February 1-14, page 44

1994 "New Anesthesia Regime Reduces High-Risk Cardiac Complications” Buffalo Physician, Summer 1994, page 2

1994 "Clinicians Remain Hopeful About Preemptive Analgesia Despite Lack of Definitive Data on Improved Outcomes"

Anesthesiology News 1994; 20(7):1 and 16-17

1995 "Higher Levels of Endogenous Peptides in CSF Found to Correlate with Less Patient Pain"

Anesthesiology News 1995; 21(2):29

1996 "Neurolytic Superior Hypogastric Plexus Blocks Shown Effective in Treating Pelvic Cancer Pain"

Anesthesiology News 1996; 22(2):20

2000 “New Pain Guidelines”WBEN News RadioBuffalo, NY

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