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Monday, October 19, 2015
In the News:
Epps receives American Physical Society’s 2016 John H. Dillon Medal
In memorial – John J. Keyes Department Seminars:
CMET Seminar John Oakey, University of Wyoming Tuesday, October 20, 2015 2:00 pm in 366 CLB “Microfluidic Encapsulation for the Design of Intra- and Extracellular Niches”
Department Seminar Israel Wachs, Lehigh University Friday, October 23, 2015 10:00 am in 102 CLB “Heterogeneous Catalysis Research in the 21st Century: Application of Operando Molecular Spectroscopy”
Neutron Day – 2015 “Solving Real World Problems with Neutrons” Wednesday, November 4, 2015 9:30 am – 3:30 pm Perkins Student Center – Rodney Room Register Now
Other Department Seminars:
Organic Journal Club Seminar Rudi Fasan, University of Rochester Thursday, October 22, 2015 12:30 pm – 219 Brown Lab “Synthesis and Application of Macrocyclic Organo-Peptide Hybrids for Targeting Protein-Protein Interactions”
Institute for Financial Services Analytics Dr. Fiona Greig, JP Morgan Chase Institute Friday, October 23, 2015 11:00 am – Lerner Graduate Hub, Room 221 “Using Big Data for the Public Good”
Dept. of Philosophy – David Norton Memorial Lecture Jason Stanley, Yale University “The War on Thugs: Propoganda, Politics, and Mass Incarceration” Friday, October 23, 2015 3:45 pm – Mitchell Hall
John Wriston Memorial Lecture, Dept. of Chemistry David Christianson, University of Pennsylvania Friday, October 23, 2015 4:00 pm – 101 Brown Lab “Directing Biosynthesis with Modular Architecture in Terpenoid Cyclases”
Biomedical Seminar Clark Hung, Columbia University Monday, November 2, 2015 10:30 am – 322 ISEB “A Paradigm for Functional Tissue Engineering of Articular Cartilage”
Jobs/Recruiting/Fellowships:
The Department of Chemical Engineering at the University of Illinois at Chicago is seeking applications for tenure-track positions at all levels with a target start date of 16 August 2016. Applications can only be accepted through the
University of Illinois at Chicago job board link https://jobs.uic.edu/job-board/job-details?jobID=57112 We will have numerous faculty openings in Chemical Engineering at Northeastern University in Boston at all faculty
ranks. Our educational and research target areas this year are in Computational Chemical Engineering and Drug
Discovery, Delivery, and Manufacturing. Details attached.
Please see attached for details on a Purdue University faculty position announcement.
Department of Chemical & Biomolecular Engineering at the University of Houston: Assistant Professor rank, in general areas of energy and health; Associate Professor rank, with expertise in biomolecular or materials engineering and applications in energy or health; Open rank position, in area of polymer science and engineering. Details attached.
The Department of Chemical and Biomedical Engineering at Cleveland State University has two openings for assistant professor of chemical engineering. More information can be found in the attached flyer and at: https://hrjobs.csuohio.edu/postings/3921
Available positions can be found on the Chemical & Biomolecular Engineering opportunity website (http://www.che.udel.edu/biz/OppIndex.html), so be sure to check it regularly.
NOVEMBER 2, 2015
Clark Hung , Ph.D. PROFESSOR OF BIOMEDICAL ENGINEERING
DIRECTOR OF CELLULAR ENGINEERING LABORATORY
COLUMBIA UNIVERSITY
“A Paradigm for Functional Tissue Engineering
of Articular Cartilage”
A rticular cartilage is the specialized con-
nective tissue that covers the ends of the
bones that comprise our diarthrodial joints
(e.g., knee and hip), and serves a critical load
bearing and lubrication function. Absent of
blood vessels, cartilage exhibits a poor intrinsic
healing capacity after injury. The aim of our
laboratory has been to engineer clinically-
relevant articular cartilage grafts for repair of
damaged and diseased joints. In this effort,
several strategies have been employed to pro-
mote development of mechanically functional
tissue including applied dynamic loading biore-
actors and growth factor optimization. In addi-
tion to surviving the demanding physical envi-
ronment, engineered cartilage grafts implanted
in pathologic joints must often survive a harsh
chemical environment. To address the latter,
we have explored strategies to precondition
developing cartilage constructs to proinflam-
matory cytokines, as well as for co-delivery of
cells and dexamethasone-laden polymer carri-
ers in engineered cartilage. While these com-
plementary research thrusts were first devel-
oped using bovine cells, our team has made
significant strides toward translation to cells of
a large preclinical animal model (canine), and
more recently to human cells.
BIOMEDICAL ENGINEERING
College of Engineering BIOMEDICAL ENGINEERING
SEMINAR
www.bme.udel.edu
10:30am in 322 ISE Lab. 10:30am in 322 ISE Lab. Refreshments served at 10:15amRefreshments served at 10:15am . .
UNIVERSITY of DELAWARE
University of Rochester Department of Chemistry
http://www.chem.rochester.edu/ faculty/faculty.php?name=fasan
219 Brown Laboratory 12:30 pm, October 22, 2015
Synthesis and Application of Macrocyclic Organo-Peptide Hybrids for Targeting Protein-Protein Interactions
Organic Journal Club Seminarnar
Rudi Fasan Ph.d.
Protein-protein interactions (PPIs) are implicated in all cellular processes from signal transduction to gene regulation, cell proliferation and apoptosis. Chemical agents capable of targeting PPIs with high potency and selectivity can provide invaluable tools for chemical biology and drug discovery but the development of such agents has represented a fundamental challenge. This seminar will present novel methodologies developed in our group for constructing macrocycles with a hybrid peptidic/non-peptidic backbone via the embedding of non-peptidic elements into genetically encoded pep-tidic frameworks. The resulting macrocycles combine a high degree of chemical complexity with a conformationally rigid architecture, providing attractive molecular scaffolds to mediate specific and high-affinity recognition of a target protein surface. This talk will discuss the investigation of these cyclization strategies with respect to their scope, mechanism, and structure-reactivity relationships and give an overview of our recent progress in applying these methods toward the discovery of natu-ral product-like macrocycles that are capable of disrupting protein-protein complexes of biomedical relevance.
Featuring guest speaker Jason Stanley, Professor, Department of Philosophy at Yale University
History regards Stalin with horror for incarcerating such a large percentage of the population of his country in forced labor camps. Yet the current US incarceration rate rivals that of the rate of Soviet citizens sent to forced labor camps during the worst period of Stalin’s Gulag.
We learn in school that prohibition ended because the United States was incarcerating too many “ordinary” Americans. Yet currently incarceration rates are far higher than during prohibition. If we are to address the problem of mass incarceration, we must change the political culture that has allowed us to demonize and dehumanize so many of our fellow citizens. This talk is an attempt to understand the propaganda that has hidden from us a reality that history will condemn.
Refreshments immediately following lecture. Free and open to the public.
Department of Philosophy presents Fall 2015 David Norton Memorial Lecture
This lecture is supported by the David Norton Memorial Fund honoring the late UD Philosophy professor, the Makiguchi Foundation, the Class of 1955 Ethics Endowment Fund, and the American Philosophical Association.
John Wriston Memorial Lecture101 Brown LaboratoryOctober 23, 2015, 4pm
Terpenoid cyclases catalyze the most complex chemical reactions in biology, in that on average, two-thirds of the carbon atoms in an isoprenoid substrate undergo changes in bonding and/or hybridization during a multi-step cyclization cascade typically proceeding through multiple carbocation intermediates. Although the substrate pool for these enzymes is limited to only a handful of linear isoprenoids, more than 70,000 terpenoid natural products have been identi-fied to date. This exquisite chemodiversity arises in part from the promiscuity of terpenoid biosynthesis, i.e., the ability of a cyclase to generate multiple products – sometimes utilizing different active sites that have evolved in different domains of a common protein fold. Crystal structures of terpenoid cyclases reveal modular architectures and catalytic strategies for carbo-cation generation, stabilization, and manipulation. Correlation of terpenoid cyclase structures and product arrays sets the foundation for understanding the biosynthetic code that directs the chemistry of carbon-carbon bond formation. As we decipher this code, we enable synthetic biology approaches for the large-scale generation of terpenoid natural products useful as phar-maceuticals, fragrances, flavorings, and fuels. Crystal structures of taxadiene synthase and ent-copalyl diphosphate synthase reveal identical protein folds. However, the active site of taxadiene synthase is in the α domain (blue), where it catalyzes the metal-dependent ionization and cyclization of geranylgeranyl diphosphate; the active site of ent-copalyl diphosphate synthase is at the interface of the β and γ domains (green and yellow, respectively), where it catalyzes the protonation-dependent cyclization of geranyl-geranyl diphosphate.
Directing Biosynthesis with Modular Architecture in Terpenoid Cyclases
David W. Christianson Ph.D.University of PennsylvaniaDepartment of Chemistryhttp://www.chem.upenn.edu/profile/david-w-christian-son
**Refreshments 3:45
OPO3PO33–
geranylgeranyl diphosphate
OPO3PO33–
ent-copalyl diphosphate
H H
taxadiene
OPO3PO34–
SCHOOL OF CHEMICAL ENGINEERING
The School of Chemical Engineering, Purdue University, seeks outstanding individuals at Assistant, Associate, or Full Professor rank with a Ph.D. or equivalent doctoral level degree in a science or engineering discipline, in areas related to solar energy and electronic device research. Exceptional individuals in other areas will also be considered. Candidates should have a distinguished academic record, outstanding potential to conduct world-class research, and a commitment to educate and mentor students. The successful candidates will conduct original research, advise graduate students, teach undergraduate and graduate level courses, and perform service both at the School and University levels. Candidates with experience working with diverse groups of students, faculty, and staff and the ability to contribute to an inclusive climate are particularly encouraged to apply. The School of Chemical Engineering at Purdue University has experienced significant growth in the past decade and has a strong faculty core engaged in all areas of Chemical Engineering as well as significant interdisciplinary efforts across campus, with other academic institutions, and industrial partners. The College of Engineering at Purdue is currently undergoing extensive growth, with over one hundred faculty position openings being projected over a five year period. For a detailed description of research activities see https://engineering.purdue.edu/ChE/Research. Submit applications online at https://engineering.purdue.edu/Engr/AboutUS/Employment/Applications, including curriculum vitae, teaching and research plans, and names of four references. For information/questions regarding applications, contact Senem Guler, Faculty Recruitment Coordinator, College of Engineering, at [email protected]. Review of applications will begin on October 12, 2015 and will continue until the positions are filled. A background check will be required for employment in this position. Nominations may be sent to Dr. Sangtae Kim, Search Committee Chair, at [email protected]. Purdue’s main campus is located in West Lafayette Indiana, a welcoming and diverse community with a wide variety of cultural activities and events, industries, and excellent schools. Purdue and the College of Engineering have a Concierge Program to assist new faculty and their partners regarding dual career needs and facilitate their relocation.
Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply.
ASSISTANT, ASSOCIATE, OR FULL PROFFESSOR The Department of Chemical Engineering at Northeastern University invites applications for
numerous tenure track positions. We seek outstanding candidates at all levels. Research areas
with an emphasis on theoretical/computational modeling are of primary interest with applications
towards process control, electrochemical systems, and materials design and processing, etc.
These areas have been identified as strategic areas of growth within the Department to
complement existing strengths in materials engineering and biological engineering. A doctoral
degree in chemical engineering or other closely related discipline is required along with a strong
record of scholarly accomplishment. Senior-level candidates should have a demonstrated record
of interdisciplinary research with national and international collaborations in both academia and
industry, and recognition for accomplished and innovative teaching. Outstanding candidates at
the assistant professor level will also be considered.
About Northeastern University: Northeastern University is located in the heart of Boston and
benefits from the intellectual and cultural vitality of an urban environment. Northeastern has
numerous international partnerships, is a premier experiential education university, and is a
National Science Foundation ADVANCE Institutional Transformation site. Faculty enjoy
collaborations with other 12 research centers headed in the college including the NSF-funded
IGERT in Nanomedicine, the Gordon Center for Subsurface Sensing and Imaging Systems
(CenSSIS), the NSF-funded Center for High-Rate Nanomanufacturing (CHN), and several other
research centers and clusters in the College of Engineering, College of Science, Bouvé College
of Health Sciences, College of Arts, Media and Design, and the College of Social Science and
Humanities. Numerous faculty within the Department have excellent collaborations with various
hospitals, universities, companies, and research facilities in the greater Boston area.
Equal Employment Opportunity
Northeastern University is an Equal Opportunity/Affirmative Action, Title IX, and an
ADVANCE institution. Minorities, women, and persons with disabilities are strongly
encouraged to apply. Northeastern University embraces the wealth of diversity represented in our
community and seeks to enhance it at all levels. Northeastern University is an E-Verify
Employer.
How to Apply
Applications must be completely submitted on-line by visiting the College website at
http://www.coe.neu.edu/coe/ and clicking on ‘Faculty Positions’. Applications should include a
cover letter, curriculum vitae, a statement of current and future research interests, a statement of
teaching interests, and contact information for at least three references. For more information,
contact Prof. Elizabeth Podlaha-Murphy ([email protected]). Review of applications will
begin immediately and will proceed until the positions are filled.
ASSISTANT, ASSOCIATE, OR FULL PROFFESSOR The Department of Chemical Engineering at Northeastern University invites applications for
numerous tenure track positions. We seek outstanding candidates at all levels. Research areas
with an emphasis on theoretical/computational modeling are of primary interest with applications
towards process control, electrochemical systems, and materials design and processing, etc.
These areas have been identified as strategic areas of growth within the Department to
complement existing strengths in materials engineering and biological engineering. A doctoral
degree in chemical engineering or other closely related discipline is required along with a strong
record of scholarly accomplishment. Senior-level candidates should have a demonstrated record
of interdisciplinary research with national and international collaborations in both academia and
industry, and recognition for accomplished and innovative teaching. Outstanding candidates at
the assistant professor level will also be considered.
About Northeastern University: Northeastern University is located in the heart of Boston and
benefits from the intellectual and cultural vitality of an urban environment. Northeastern has
numerous international partnerships, is a premier experiential education university, and is a
National Science Foundation ADVANCE Institutional Transformation site. Faculty enjoy
collaborations with other 12 research centers headed in the college including the NSF-funded
IGERT in Nanomedicine, the Gordon Center for Subsurface Sensing and Imaging Systems
(CenSSIS), the NSF-funded Center for High-Rate Nanomanufacturing (CHN), and several other
research centers and clusters in the College of Engineering, College of Science, Bouvé College
of Health Sciences, College of Arts, Media and Design, and the College of Social Science and
Humanities. Numerous faculty within the Department have excellent collaborations with various
hospitals, universities, companies, and research facilities in the greater Boston area.
Equal Employment Opportunity
Northeastern University is an Equal Opportunity/Affirmative Action, Title IX, and an
ADVANCE institution. Minorities, women, and persons with disabilities are strongly
encouraged to apply. Northeastern University embraces the wealth of diversity represented in our
community and seeks to enhance it at all levels. Northeastern University is an E-Verify
Employer.
How to Apply
Applications must be completely submitted on-line by visiting the College website at
http://www.coe.neu.edu/coe/ and clicking on ‘Faculty Positions’. Applications should include a
cover letter, curriculum vitae, a statement of current and future research interests, a statement of
teaching interests, and contact information for at least three references. For more information,
contact Prof. Elizabeth Podlaha-Murphy ([email protected]). Review of applications will
begin immediately and will proceed until the positions are filled.
University of Houston
Department of Chemical and Biomolecular Engineering
ASSOCIATE PROFESSOR FACULTY POSITION
The Chemical and Biomolecular Engineering Department at the University of Houston seeks faculty candidates at the rank of Associate Professor. Candidates should have an established record of excellence in research, mentoring, and teaching. We are particularly interested in candidates with expertise in health or energy related areas.
Appointment to our faculty requires a PhD in Chemical Engineering or a related field.
Applications should be submitted online at http://jobs.uh.edu
You will need to provide (i) a detailed Curriculum Vitae, which should include lists of doctoral students graduated and funding received, (ii) a detailed description of research interests and accomplishments ( ≤ 5 pages), (iii) a teaching statement covering your experience, accomplishments, and interests ( ≤ 2 pages), (iv) copies of three of your publications, and (v) the names and email addresses of three references who we may contact.
The University of Houston is an Equal Opportunity/Affirmative Action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.
http://www.chee.uh.edu
University of Houston
Department of Chemical and Biomolecular Engineering
JUNIOR FACULTY POSITION
The Chemical and Biomolecular Engineering Department at the University of Houston seeks tenure track faculty candidates at the rank of Assistant Professor. The successful candidate must show exceptional promise for pioneering research and effective teaching. We are particularly interested in biomolecular or materials engineering with applications in health or energy.
Appointment to our faculty requires a PhD in Chemical Engineering or a related field.
Applications should be submitted online at http://jobs.uh.edu
You will need to provide your Curriculum Vitae, a detailed description of research interests (not to exceed 10 pages), teaching philosophy statement (2 pages), copies of three of your publications, and the names and email addresses of three references who we may contact.
The University of Houston is an Equal Opportunity/Affirmative Action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.
http://www.chee.uh.edu
University of Houston
Department of Chemical and Biomolecular Engineering
FACULTY POSITION in POLYMER SCIENCE & ENGINEERING
The Department of Chemical and Biomolecular Engineering (ChBE) at the University of Houston seeks faculty candidates (open rank) in the area of polymer science and engineering, to join a growing interdisciplinary polymer center spanning ChBE and the Department of Chemistry. The successful candidate should have demonstrated potential to conduct pioneering research in polymers that spans the fundamentals to applications. Candidates at the associate and full professor level should have an established record of excellence in scholarship and collaborative research.
Appointment to our faculty requires a PhD in Chemical Engineering or a related field.
Applications should be submitted online at http://jobs.uh.edu
Candidates should provide a Curriculum Vitae, detailed description of research interests (not to exceed 10 pages), copies of three of your publications, and the names and email addresses of three references whom we may contact.
The University of Houston is an Equal Opportunity/Affirmative Action employer. Women, minorities, veterans, and persons with disabilities are encouraged to apply.
http://www.chee.uh.edu
