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Alexandre Gramfort Telecom ParisTech - CNRS LTCI - CEA Neurospin [email protected] Mining brain waves with MNE GitHub : @agramfort Twitter : @agramfort http://martinos.org/mne/stable/index.html

Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

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Page 1: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Alexandre Gramfort

Telecom ParisTech - CNRS LTCI - CEA [email protected]

Mining brain waves with MNE

GitHub : @agramfort Twitter : @agramfort

http://martinos.org/mne/stable/index.html

Page 2: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

B

NeuralCurrent(post synaptic)

EquivalentCurrentDipole

dB/dz MEG recordings

First EEG recordings

in 1929by H. Berger

ENeuralCurrent(post synaptic)

EquivalentCurrentDipole

V EEG recordings

EEG & MEG: non-invasive electrophy

First whole head MEG 1992

Page 3: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

EEG :• ≈ 100 sensors

MEG :• ≈ 150 to 300 sensors

Sampling between 250 and1000 Hz

Sample EEG measurements

M/EEG Measurements

High temporal resolution

Page 4: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

subject fsaveragemorphing

Page 5: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

The landscape of M/EEGsoftware development

eeglab(UCSD)

UCLSPM

MEEG

DondersFieldtrip

Nutmeg

(UCSF)(Konstanz)

Brainstorm(Mc Gill)

Page 6: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Development of the MNE softwarebefore 2010

Harvard

Page 7: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Development of the MNE softwarein 2014

Berkeley

ParisHarvard

NYU

Cambridge Aalto

IlmenauJuelich

Sheffield

U. Wash.

UCSF

Gratz

Page 8: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

• MNE based on C code developed for ~15 years by MSH• MNE-Python started in Dec. 2010 at MGH, Boston

About the project

Source: https://www.ohloh.net/p/MNE

Page 9: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software
Page 10: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Demo

Page 11: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Objective

https://www.kaggle.com/c/decoding-the-human-brain

Organized by: E. Olivetti, M. Kia, P. Avesani, N. Weisz (Univ. of Trento, IT),D. Wakeman (Harvard, USA), R. Henson (MRC/CBU, Cambridge, UK),O. Jensen (Donders Institute, NL), and A. Gramfort (Telecom ParisTech, CEA)

Page 12: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Objective

Every 1s or 2s

Can we classify if subject saw a face or scrambled face?

Page 13: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

MEGSensor 1 (fT)

MEGSensor 2

(fT) xi s.t. yi = 1

xi s.t. yi = -1

Objective

Page 14: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Hacking time…

Page 15: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Get inspired ...http://martinos.org/mne/auto_examples/index.html

Page 16: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Ask for helphttp://martinos.org/mne/

http://mail.nmr.mgh.harvard.edu/mailman/listinfo/mne_analysis

Mailing list:

Page 18: Mining brain waves with MNE...SPM MEEG Donders Fieldtrip Nutmeg (UCSF) (Konstanz) Brainstorm (Mc Gill) Development of the MNE software before 2010 Harvard Development of the MNE software

Alexandre [email protected]:

References

Funding:

MNE software for processing MEG and EEG data, A. Gramfort, M. Luessi, E. Larson, D. Engemann, D. Strohmeier, C. Brodbeck, L. Parkkonen, M. Hämäläinen, Neuroimage, 2014

MEG and EEG data analysis with MNE-Python, A. Gramfort, M. Luessi, E. Larson, D. Engemann, D. Strohmeier, C. Brodbeck, R. Goj, M. Jas, T. Brooks, L. Parkkonen, M. Hämäläinen, Frontiers in Neuroscience, 2013

GitHub : @agramfort Twitter : @agramfort

NIH, NSF, Google (GSOC 2013, 2014)